Silver Patents (Class 424/618)
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Patent number: 8383674Abstract: Silver nanoclusters were synthesized by reducing silver nitrate with ethylene glycol at a certain temperature in the presence of zeolite. A one-pot procedure rendered uniform size distributions of quasi-spherical silver clusters synthesized on the surfaces of cubic-like zeolite.Type: GrantFiled: July 1, 2010Date of Patent: February 26, 2013Assignee: University of Puerto RicoInventor: Yury Posada
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Patent number: 8383696Abstract: A water-absorbent resin composition having an antimicrobial property, which suppresses the generation of dust of the antimicrobial agent. A water-absorbent resin composition comprising a water-absorbent resin and an antimicrobial agent comprising an inorganic compound carrying an antimicrobial metal, the water-absorbent resin composition being characterized in that the degree of generated dust of the water-absorbent resin composition is at most 100 CPM. The water-absorbent resin composition of the present invention can be suitably used as hygienic materials such as disposable diaper, sanitary napkin and incontinence pad; urine-absorbent materials for pets; materials for civil engineering and construction such as packing materials; drip absorbents; food freshness retaining materials such as cold-reserving agents; horticultural articles such as water-retaining materials for soils; and the like.Type: GrantFiled: November 23, 2011Date of Patent: February 26, 2013Assignee: Sumitomo Seika Chemicals Co., Ltd.Inventors: Takayasu Taniguchi, Tatsuya Oida, Yasuhiro Nawata
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Publication number: 20130045281Abstract: Disclosed is a process for preparing silver ions (Ag+) comprising treating element metal silver (Ag0) under high temperature and high pressure, and quickly cooling to directly obtain the silver ions (Ag+).Type: ApplicationFiled: November 6, 2009Publication date: February 21, 2013Inventor: Raymond CHIN
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Publication number: 20130045252Abstract: An apparatus for adsorption of body odour comprising: an activated carbon layer for adsorbing body odour; a first material layer; and wherein the activated carbon layer is coupled to the first material layer.Type: ApplicationFiled: April 6, 2011Publication date: February 21, 2013Inventors: Thomas Douglas Rawlings, Stephen Anthony Rawlings, Robert Holmquist
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Publication number: 20130039953Abstract: A method for treating a surface with a therapeutic agent is disclosed. The method comprises precipitating a therapeutic agent from a hydrophilic polymeric base layer with which the therapeutic agent has been complexed, to form a layer comprising microparticles of the therapeutic agent on the hydrophilic polymeric base layer, the hydrophilic polymeric base layer being grafted to the surface. Devices comprising a surface having a hydrophilic polymeric base layer comprising a hydrophilic polymer grafted to the surface and a layer comprising microparticles of a therapeutic agent disposed on and complexed with the hydrophilic polymeric base layer are also disclosed.Type: ApplicationFiled: July 6, 2012Publication date: February 14, 2013Applicant: Covalon TechnologiesInventors: Vyacheslav Dudnyk, Valerio DiTizio
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Patent number: 8367089Abstract: Nanosilver coated bacterial cellulose nanofiber and a method of producing the nanosilver coated bacterial cellulose nanofiber. The nanosilver coated bacterial cellulose nanofiber is produced by preparing a suspension of bacterial cellulose fibers, oxidizing bacterial cellulose fibers; adding the thio-group to the polymer backbone; reacting the resulting product with silver proteinate and enhancing the nanosilver particle size. The nanosilver coated bacterial cellulose nanofibers exhibit antimicrobial properties.Type: GrantFiled: April 24, 2007Date of Patent: February 5, 2013Assignee: Axcelon Biopolymers CorporationInventors: Wankei Wan, Ganesh Guhados
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Publication number: 20130028984Abstract: Tissue fillers derived from decellularized tissues are provided. The tissue fillers can include acellular tissue matrices that have reduced inflammatory responses when implanted in a body. Also provided are methods of making and therapeutic uses for the tissue fillers.Type: ApplicationFiled: July 27, 2012Publication date: January 31, 2013Inventors: Hui Xu, Wenquan Sun, Hua Wan, Rick Owens
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Publication number: 20130025764Abstract: Methods for increasing the effectiveness of one or more antimicrobial agents incorporated in polymeric films are described. The methods involve adding an antimicrobial agent promoter to the polymer prior to or when forming the film. The antimicrobial agent promoter is a blowing agent, a hydrophilic wetting agent, and/or both. Also described are polymeric films comprising antimicrobial agents and such promoters, and multilayer barrier assemblies using such films. The multilayer barrier assemblies find wide application in the medical field. Also described are multilayered polymeric films comprising a first skin layer that includes at least one gas and vapor barrier organic polymer, a core layer that comprises at least one elastomeric organic polymer, and a second skin layer that comprises at least one sealable organic polymer and at least one antimicrobial agent. Articles comprising the film are useful in various applications to include medical and health care applications.Type: ApplicationFiled: March 25, 2011Publication date: January 31, 2013Applicant: AVERY DENNISON CORPORATIONInventor: Kevin O. Henderson
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Publication number: 20130029029Abstract: Compositions for bath aids and other hard surfaces having silver-based antimicrobial efficacy are disclosed. A variety of hard surfaces are suitable for use of the invention. Methods for reducing or eliminating bacterial growth using a silver-based antimicrobial additives in a hard surface are also disclosed. Preferably, the silver-based antimicrobial additive according to the invention may be formed into any desired shape for its desired uses.Type: ApplicationFiled: July 26, 2012Publication date: January 31, 2013Applicant: BRIGGS MEDICAL SERVICE COMPANYInventor: William Davis
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Patent number: 8361513Abstract: The present invention herein provides antimicrobial zeolite which hardly causes any color change with the elapse of time even when it is incorporated into a resin to form an antimicrobial resin composition. The present invention thus relates to antimicrobial zeolite which comprises zeolite whose ion-exchangeable ions are partially or wholly replaced with hydrogen ions and silver ions; and an antimicrobial resin composition which comprises the foregoing antimicrobial zeolite in an amount ranging from 0.05 to 80% by mass.Type: GrantFiled: April 22, 2011Date of Patent: January 29, 2013Assignee: Sinanen Zeomic Co., Ltd.Inventors: Akio Taniguchi, Kumiko Miyake, Yasuo Kurihara
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Publication number: 20130022658Abstract: Embodiments relate to depositing a layer of antimicrobial material such as silver on a permeable substrate using atomic layer deposition (ALD). A deposition device includes two injectors that inject source precursor, reactant precursor, purge gas or a combination thereof onto the permeable substrate that passes between the injectors. Part of the gas injected by an injector penetrates the permeable substrate and is discharged by the other injector. The remaining gas injected by the injector moves in parallel to the surface of the permeable substrate and is discharged via an exhaust portion formed on the same injector. While penetrating the substrate or moving in parallel to the surface, the source precursor or the reactant precursor becomes absorbed on the substrate or react with precursor already present on the substrate to deposit the antimicrobial material on the substrate.Type: ApplicationFiled: June 27, 2012Publication date: January 24, 2013Applicant: SYNOS TECHNOLOGY, INC.Inventor: Sang In LEE
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Publication number: 20130011490Abstract: This invention relates to a “high lower alcohol content” (>40% v/v of a C1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise an alcohol, C1-4 (>40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and moisturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.Type: ApplicationFiled: September 10, 2012Publication date: January 10, 2013Applicant: DEB WORLDWIDE HEALTHCARE INC.Inventors: Maria Teresa Fernandez de Castro, Bruce Michael Koivisto, Francisco Munoz
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Publication number: 20130011492Abstract: A method of electrochemical deposition includes submerging a stainless steel surface of an object in a chitosan solution and applying a first electric potential between the submerged stainless steel surface and the chitosan solution for a predetermined time to form a chitosan surface coating. After rinsing and dehydrating, the chitosan coated surface is submerged in a solution having a predetermined concentration of a noble metal nitrate and a second electric potential is applied between the chitosan coated surface and the solution of the noble metal nitrate to deposit noble metal particles on the chitosan surface coating.Type: ApplicationFiled: August 24, 2012Publication date: January 10, 2013Applicant: The Research Foundation of State University of New YorkInventors: Gary HALADA, Michael A. CUIFFO, Prashant JHA
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Publication number: 20130004586Abstract: Compositions, solid polymeric compositions, and/or articles of manufacture are provided that can include a polymer matrix having a plurality of ion-exchange particles distributed therein. Products by process are provided that can include prior to solidifying the polymeric precursors, blending the precursors with ion-exchange particles to form a mixture, and solidifying the mixture to form a solid polymeric composition product. Solid polymeric composition production methods are also provided that can include providing a plurality of ion-exchange particles, prior to solidifying the polymeric precursors, blending the precursors with the ion-exchange particles to form a mixture, and solidifying the mixture to form a solid polymeric composition. Article of manufacture production methods are provided that can include incorporating a solid polymeric composition into an article of manufacture, the solid polymeric composition including a polymer matrix and a plurality of ion-exchange particles distributed therein.Type: ApplicationFiled: June 25, 2012Publication date: January 3, 2013Inventors: David J. Vachon, Nathan Knapp
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Publication number: 20130004585Abstract: Methods of fabricating implantable medical devices, preferably with PEEK, having antimicrobial properties, are disclosed. The antimicrobial effect is produced by incorporating ceramic particles containing antimicrobial metal cations into molten PEEK resin, which is subsequently allowed to cool and set in its final shape achieved by injection molding, cutting and machining or other techniques.Type: ApplicationFiled: December 10, 2010Publication date: January 3, 2013Applicant: DIFUSION TECHNOLOGIES, INC.Inventors: Joseph J. Crudden, Jami Hafiz, James E. Deaton, John R. Pepper, Derrick Johns
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Publication number: 20130004587Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.Type: ApplicationFiled: September 14, 2012Publication date: January 3, 2013Applicant: SCIESSENT LLCInventor: Joseph J. Crudden
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Patent number: 8343535Abstract: Disclosed are a hydrogel dressing for covering or treating a wound and a method for preparing the same. The hydrogel dressing includes a matrix structure of a cross-linked mixture, and an elastic sheet coated with an elementary metal or ionic metal embodied in the matrix structure. The mixture comprises a hydrophilic polymer, about 0.5 to about 5 wt % of a photocatalyst agent and at least 80 wt % of water based on the total weight of the mixture.Type: GrantFiled: February 25, 2008Date of Patent: January 1, 2013Assignee: The Chinese University of Hong KongInventors: Andrew Burd, Michael Wing Wai Tsang
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Publication number: 20120330210Abstract: Antimicrobial silicone-based dressings, such as wound dressings, are disclosed. An example dressing comprises a transparent and self-adhesive gel sheet cured from a liquid containing silicone, the sheet having dispersed therein (i) particulates of a chlorhexidine compound that is not soluble in the liquid; and (ii) at least one other antimicrobial. Methods of making the silicone-based dressings and methods of use are also disclosed.Type: ApplicationFiled: August 30, 2012Publication date: December 27, 2012Applicant: Covalon Technologies Inc.Inventors: Liu Yang, Valerio DiTizio
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Publication number: 20120328713Abstract: The invention pertains to methods and compositions for preventing or reducing microbial contamination using a silver (III) periodate as antimicrobial active hi a preferred embodiment the silver (III) periodate is used in a coating upon a medical device or implant to confer coating uniformity and antimicrobial efficacy. Also provided is a method of synthetising a silver (III) periodate in high yield by heating a source of single valency silver ions in water and subsequently combining it with a heated solution comprising persulfate, a by droxide, and a periodate.Type: ApplicationFiled: December 14, 2010Publication date: December 27, 2012Inventors: Merle E Olson, Nick Allan, Amin Mousa Omar, Justin J Anderson, Patricia L Nadworny, Michael W Harding
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Publication number: 20120321686Abstract: The present invention relates to antifungal materials, particularly to nanoparticles comprising or consisting of a non-persistent inorganic support material such as Tricalciumphosphate (TCP) and copper as a dopant in the form of Cu+/?0, Cu+1 and or Cu+2; to composite materials or liquid formulations containing such nanoparticles. Further, the invention relates to the manufacture of such nanoparticles, composites, liquid formulations and to the use of such nanoparticles, composites, liquid formulations as an antifungal component.Type: ApplicationFiled: December 24, 2009Publication date: December 20, 2012Applicants: ETH Zurich, PERLEN CONVERTING AGInventors: Stefan Bokorny, Tobias Maienfisch, Stefan Loher, Wendelin J. Stark
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Publication number: 20120321603Abstract: A composition and treatment method are disclosed for one or more of alpha, beta, and gamma-Cyclodextrin and a natural molecule or fragment thereof wherein the natural molecule is sometimes Glutathione, is non-acetylated, non-Esterified, and non-fatty acid attached, and the composition is administered parenterally and non-interveneously.Type: ApplicationFiled: June 18, 2012Publication date: December 20, 2012Inventors: Nayan Patel, Chinh Tran
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Publication number: 20120322903Abstract: An antimicrobial polyurethane foam that is formed from: a multi-functional isocyanate component; an aqueous polyol component reactive with the multi-functional isocyanate component; an antimicrobial metallic compound; and a complexing agent. The complexing agent is used to form a stable blend of the antimicrobial metallic compound with the polyol component. Exemplary complexing agents include amine compounds, ammonium-containing compounds and ammonia as well as combinations these compounds. The antimicrobial metallic compound can be a silver, zinc or copper compound. Desirably, the antimicrobial metallic compound is silver saccharinate. A process of making the antimicrobial polyurethane foam and stable blends used in the manufacture of the antimicrobial polyurethane foam are also disclosed.Type: ApplicationFiled: June 11, 2012Publication date: December 20, 2012Inventors: Bhalchandra M. Karandikar, Bruce Lance Gibbins
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Publication number: 20120321691Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.Type: ApplicationFiled: August 23, 2012Publication date: December 20, 2012Applicant: Z-medica CorporationInventors: Raymond J. Huey, Denny Lo, Daniel J. Burns, Giacomo Basadonna, Francis X. Hursey
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Publication number: 20120321689Abstract: The present invention relates to an antibacterial resin composition derived from a master batch, an antibacterial fiber, an antibacterial film, and a producing method of an antibacterial resin composition therefrom, comprising a polyethylene terephthalate resin as the component (A), and a polybutylene terephthalate resin as the component (B), an antibacterial glass which elutes silver ions as a component (C), which is characterized by having a composition formulated below. (A) a polyethylene terephthalate resin: 100 pbw (B) a polybutylene terephthalate resin: 0.5 to 25 pbw (C) an antibacterial glass: 0.1 to 10 pbw.Type: ApplicationFiled: October 20, 2011Publication date: December 20, 2012Applicant: KOA GLASS CO., LTD.Inventor: Yoshinao Kobayashi
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Publication number: 20120316259Abstract: This invention relates to a process for the co-encapsulation of biocidally active ingredients in a clay mineral, the process comprising the step of bringing the clay mineral into contact with a biocidally active nitrogen compound that contains at least one hydrocarbon group with 6 to 20 carbon atoms, and at the same time or subsequently with at least one biocidally active compound selected from the group consisting of 2-n-octyl-4-isothiazoline-3-one, 3-iodopropenylbutyl-carbamate and tetrahis(hydroxymethyl)phosphonium sulfate. And the use of such encapsulated product in water based paints, coatings and varnishes.Type: ApplicationFiled: February 15, 2011Publication date: December 13, 2012Applicant: CLARIANT S.A. BRAZILInventors: Antonio Pedro de Oliveira Filho, Wagner Claudio Da Silva, Manlio Gallotti, Alexandra Paschoalin Menezes, Karine Framesqui Righi, Marcia Regina Da Silva Rios
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Publication number: 20120315340Abstract: Methods of post-loading ceramic particles with antimicrobial metal cations are disclosed. In certain embodiments, the post-loaded particles are zeolites, wherein the zeolites have been incorporated into a resin and the combination is used as an implantable device. In certain embodiments, the polymer is a thermoplastic polymer such as polyaryletheretherketone (PEEK). In certain embodiments, the source of antimicrobial activity includes ion-exchangeable cations contained in a zeolite. In certain embodiments, disclosed are methods of imparting antimicrobial activity to devices by controlling the delivery of certain cations through ion-exchange via a zeolite incorporated in the device.Type: ApplicationFiled: November 24, 2010Publication date: December 13, 2012Applicant: DIFUSION TECHNOLOGIES, INC.Inventors: Joseph J. Crudden, Derrick Johns
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Publication number: 20120308666Abstract: Silica nanopowders with biocidal properties, especially for polymer composites, are produced by sol-gel method. The silica sol is produced from the aqueous mixture containing tetraalkoxysilane, in which alkoxy group contains from C1 to C4 carbon atoms, an alcohol or the mixture of aliphatic alcohols from C1 to C4, in the mole ratio of 1:5 to 1:35, in the presence of ammonium compound, used in an amount of from 0.001 to 0.05 mol per 1 mol of tetraalkoxysilane, with introducing, after thorough mixing of components, the silver salt in the form of aqueous solution in an amount from 0.02 to 1 mol per 1 mol of tetraalkoxysilane, and subsequently the aqueous solution of alkali metal hydroxide in an amount from 0.02 to 1 mol of hydroxide per 1 mol of tetraalkoxysilane.Type: ApplicationFiled: January 21, 2011Publication date: December 6, 2012Applicant: Instytut Chemii Przemyslowej Im. Prof Ignacego MoscickeigoInventors: Maria Zielecka, Elzbieta Bujnowska, Magdalena Wenda, Regina Jeziórska, Krystyna Cyruchin, Anna Pytel, Blanka Kepska
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Publication number: 20120301553Abstract: A colloidal dispersion having carrier particles of silica having a particle size from 3 nm to 100 nm to which silver ions have been adsorbed, preferably in an amount of 0.0005-5 silver ions per nm2 of silica particle surface. The surface of the carrier particles of silica suitably contains aluminumsilicate sites. It also relates to a process for making a colloidal dispersion comprising providing a silica sol, adding a solution of silver nitrate to the silica sol under agitation yielding a colloidal dispersion with silver ions adsorbed on the surface of the silica particles. The dispersion is usable as a biocide in e.g. coatings, adhesives and sealants, in surface treatment and impregnation of organic materials, in surface treatment and impregnation of inorganic materials, in textiles, garments and shoes, in medical disposables, in plastics and rubbers, in water and air purification, and in crop protection.Type: ApplicationFiled: September 20, 2010Publication date: November 29, 2012Applicant: PREBONA ABInventor: Jan-Erik Otterstedt
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Publication number: 20120301528Abstract: Embodiments of the invention are directed to a composition having antimicrobial activity comprising particles comprising at least one inorganic copper salt; and at least one functionalizing agent in contact with the particles, the functionalizing agent stabilizing the particle in a carrier such that an antimicrobially effective amount of ions are released into the environment of a microbe. The average size of the particles ranges from about 1000 nm to about 4 nm. Preferred copper salts include copper iodide, copper bromide and copper chloride. Preferred functionalizing agents include amino acids, thiols, hydrophilic polymers, emulsions of hydrophobic polymers and surfactants.Type: ApplicationFiled: May 24, 2012Publication date: November 29, 2012Inventors: Donald R. Uhlmann, Anoop Agrawal, Murat Akarsu, John P. Cronin, Juan Carlos Lopez-Tonazzi, Ryan J. Reeser
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Publication number: 20120301533Abstract: Embodiments of the invention are directed to a composition having antimicrobial activity comprising particles comprising at least one inorganic copper salt; and at least one functionalizing agent in contact with the particles, the functionalizing agent stabilizing the particle in a carrier such that an antimicrobially effective amount of ions are released into the environment of a microbe. The average size of the particles ranges from about 1000 nm to about 4 nm. Preferred copper salts include copper iodide, copper bromide and copper chloride. Preferred functionalizing agents include amino acids, thiols, hydrophilic polymers emulsions of hydrophobic polymers and surfactants.Type: ApplicationFiled: June 20, 2012Publication date: November 29, 2012Inventors: Donald R. Uhlmann, Anoop Agrawal, Juan Carlos Lopez-Tonazzi, Ryan J. Reeser
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Publication number: 20120301530Abstract: Embodiments of the invention are directed to a composition having antimicrobial activity comprising particles comprising at least one inorganic copper salt; and at least one functionalizing agent in contact with the particles, the functionalizing agent stabilizing the particle in a carrier such that an antimicrobially effective amount of ions are released into the environment of a microbe. The average size of the particles ranges from about 1000 nm to about 4 nm. Preferred copper salts include copper iodide, copper bromide and copper chloride. Preferred functionalizing agents include amino acids, thiols, hydrophilic polymers emulsions of hydrophobic polymers and surfactants.Type: ApplicationFiled: June 14, 2012Publication date: November 29, 2012Inventors: Donald R. Uhlmann, Anoop Agrawal, Murat Akarsu, John P. Cronin
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Publication number: 20120294919Abstract: The invention is directed to an antimicrobial metal composite formed by vaporizing an antimicrobial metal or antimicrobial metal salt such as silver, copper or salts thereof using an plasma system and cooling the formed vapor in the presence of a fluidized gas of filler powder. Alternatively, the filler or a filler precursor is entrained with the antimicrobial metal or antimicrobial metal precursor and vaporized and then upon cooling the antimicrobial metal vapor and filler vapor condense to form the composite. The composite shows high antimicrobial activity and can be incorporated into or onto polymers, coatings, textiles, paper, gels (for example for wound care), lubricants, adhesives and cosmetics or pharmaceutical, especially medical devices.Type: ApplicationFiled: May 14, 2012Publication date: November 22, 2012Applicant: BASF SEInventors: Bingham Scott Jaynes, Matthew Edward Gande, Ryan James Fenton, Urs Leo Stadler, Marc Mamak, Sungyeun Choi
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Publication number: 20120288488Abstract: Compositions and methods for preventing or controlling bacteria, viruses and parasitic growths that cause diarrhea, pneumonia and septicemia in animals comprising a biocidal system comprised of a primary biocide and a pH buffer component; a cationic or ionic surfactant having an HLB of from about 5 to about 30; a thickening agent; and an aqueous based carrier.Type: ApplicationFiled: January 9, 2012Publication date: November 15, 2012Applicant: NOBLE ION, LLCInventors: Burt R. Sookram, John W. Veenstra
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Publication number: 20120288553Abstract: The present invention provides a method for controlling toxicity of metallic particles and a low-toxicity composite of metallic nanoparticles and inorganic clay. The metallic nanoparticles are effective in preventing infection and in skinning over, and thus suitable for treating scalds/burns. In the composite, the weight ratio of metallic nanoparticles to inorganic clay preferably ranges 0.1/99.9 to 6.0/94.0 in a size of about 5 to 100 nm. Preferably, the metal is silver and the inorganic clay is nano silicate platelets.Type: ApplicationFiled: July 14, 2012Publication date: November 15, 2012Applicant: NATIONAL TAIWAN UNIVERSITYInventors: Jiang-Jen Lin, Hong-Lin Su, Fu-Chuo Peng, Chia-Yu Chu, Ying-Fang Chiu, Pei-Ru Li, Hsi-Tai Sun
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Patent number: 8309117Abstract: The present invention provides a method for preparing a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating on a medical device, wherein the antimicrobial metal-containing LbL coating comprises at least one layer of a negatively charged polyionic material having —COOAg groups and/or silver nanoparticles formed by reducing Ag+ ions associated with the —COO? groups of the negatively charged polyionic material. In addition, the present invention provides a medical device prepared according to a method of the invention.Type: GrantFiled: December 10, 2003Date of Patent: November 13, 2012Assignee: Novartis, AGInventors: Michael F. Rubner, Sung Yun Yang, Yongxing Qiu, Lynn Cook Winterton, John Martin Lally
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Publication number: 20120282348Abstract: An antimicrobial therapeutic hydrogel composition comprises a pharmaceutical and/or medical grade silver salt, and an Aloe vera gel or extract. The composition could also include stabilizing agents, a non-ionic surfactant, polyol, and hydrophilic hygroscopic polymers. The resulting product has potent antimicrobial activity against bacteria, protozoa, fungi and viruses. The antimicrobial therapeutic composition can serve as a treatment for burns and as a wound/lesion dressing that either donates or receives moisture to provide a physiologic environment for accelerated wound healing and the relief of pain.Type: ApplicationFiled: May 5, 2011Publication date: November 8, 2012Inventors: Kenneth M. Yates, Celia A. Proctor, Dan H Atchley
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Publication number: 20120282347Abstract: Disclosed is a process for preparing silver ions (Ag+) comprising treating element metal silver (Ag0) under high temperature and high pressure, and quickly cooling to directly obtain the silver ions (Ag+).Type: ApplicationFiled: November 6, 2009Publication date: November 8, 2012Inventor: Raymond Chin
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Patent number: 8303970Abstract: The present invention relates to a method of covering a metal article with a film formed from the melting of a thin layer of powder comprising: physically blending 99.8 to 97% by weight of at least one polyamide and 0.2 to 3% by weight of an inorganic biocide species consisting of a soluble ceramic in which silver ions are encapsulated to form a powder blend composition; contacting the metal article with said powder composition blend to form a thin layer of said powder on the article; melting the powder blend composition onto the metal article to form a thin coating film; and cooling the coated article; where the powder blend composition is free of zinc compounds.Type: GrantFiled: April 15, 2010Date of Patent: November 6, 2012Assignee: Arkema FranceInventors: Adrien Lapeyre, Christian Gancet
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Publication number: 20120276183Abstract: An absorbent product intended particularly for use as a wound dressing comprises an admixture of carboxymethyl chitosan and chitosan wherein the chitosan incorporates at least one antimicrobial agent. Absorbency is provided by the carboxymethyl chitosan and antimicrobial properties by the antimicrobial agent incorporated in the chitosan.Type: ApplicationFiled: December 23, 2010Publication date: November 1, 2012Inventor: Colin Bradford
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Publication number: 20120276205Abstract: A formulation including at least one silver oxide including a silver(II) oxide, the silver(II) oxide having an irregular macrocrystal structure, the silver oxide having an average particle size (D50) below 8 micrometers, the irregular macrocrystal structure characterized by a diffraction peak in a {111} diffraction plane having at least one of the following structural properties: (i) a measured full width half maximum (FWIIM) of the peak being at least 0.24 degrees of 2?; and (ii) a net full width half maximum (net FWHM) of the peak being at least 0.14 degrees of 2?.Type: ApplicationFiled: November 7, 2010Publication date: November 1, 2012Applicant: AIDANCE SKINCARE & TOPICAL SOLUTIONS LLCInventors: Aharon Weissman, Perry Antelman, Shalom Lampert
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Patent number: 8293267Abstract: There is provided a method for preparing a natural cellulose-OAg matrix having antimicrobial activity without leaching silver from the cellulose-OAg matrix. The method comprises: introducing silver ions (Ag+) into a natural cellulose matrix by dipping the natural cellulose matrix in an AgCl-dissolved NH4OH solution; and substituting hydrogen (H) of hydroxyl group (—OH) in natural cellulose with Ag+ by drying the silver ion-infused natural cellulose matrix, thus to form a natural cotton-OAg complex. The cellulose-OAg matrix prepared in the method may be useful to continuously maintain antimicrobial activity by maintaining an effective concentration of silver, which does not have cytotoxicity to human skin, and chemically bonded silver is not leached during the rehydration due to the chemical bond between the silver and the cellulose matrix.Type: GrantFiled: June 12, 2009Date of Patent: October 23, 2012Assignee: AG Biotech, LLCInventor: Ju Young Kim
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Publication number: 20120261054Abstract: The invention relates to a covering (1) for objects, in particular in public facilities and/or means of transportation, for preventing the transmission of infections, the covering being made of covering material, in particular having a virucidal and/or virostatic and/or bactericidal and/or bacteriostatic and/or fungicidal and/or fungistatic effect, wherein the covering material is intended to be applied externally to surfaces (2) of objects. According to the invention, the covering material is flexible and can be adapted to the outer shape of the object.Type: ApplicationFiled: August 27, 2010Publication date: October 18, 2012Inventor: Hasso von Blücher
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Patent number: 8287893Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.Type: GrantFiled: May 19, 2008Date of Patent: October 16, 2012Assignee: Sciessent LLCInventor: Joseph J. Crudden
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Publication number: 20120258179Abstract: Provided is an antibacterial water treatment agent using polyethylene containing silver zeolite which offers various benefits such as being very safe, wherein such antibacterial water treatment agent is characterized in that the silver zeolite has a type-A crystalline structure and is contained by 10 to 60 percent by weight, and the antibacterial water treatment agent is a porous body having continuous holes formed from the silver zeolite to the surface of the antibacterial water treatment agent, wherein the continuous holes are created by vaporization of crystallization water contained in the silver zeolite.Type: ApplicationFiled: December 7, 2011Publication date: October 11, 2012Inventor: Kenji Nakamura
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Patent number: 8282951Abstract: Antimicrobial coatings to protect surfaces and a method of applying such a coating are disclosed. An antimicrobial coating may be applied to a surface, such as the interior surface of a building's exterior wall. The interior surface must be accessed, and then an antimicrobial coating is provided and applied. The antimicrobial coating includes an inorganic antimicrobial additive and a colloidal polymeric medium. The inorganic antimicrobial additive may be silver, platinum, gold, palladium, copper, zinc, boron, or a compound of any of those elements. By including an ultraviolet tracer or color dye additive in the coating, it is possible to detect the coating at any time, provided that the surface is accessed.Type: GrantFiled: January 4, 2010Date of Patent: October 9, 2012Assignee: EnviroCare CorporationInventor: Bryan M. Redler
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Patent number: 8282949Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising metal-acid solutions.Type: GrantFiled: May 19, 2008Date of Patent: October 9, 2012Assignee: Sciessent LLCInventor: Joseph J. Crudden
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Publication number: 20120251627Abstract: The present invention is directed to an antimicrobial composition, comprising pyrithione or a pyrithione complex; and a zinc or copper or silver source selected from the group consisting of zinc or copper or silver salts, oxides, hydroxides, sulfates, chlorides, metals, and combinations thereof; wherein the weight ratio of the zinc or copper or silver source to the pyrithione or the pyrithione complex is in the range from about 1:300 to about 50:1, and wherein the antimicrobial composition has an enhanced biocidal effect against a variety of free-living microorganisms or biofilms. Also disclosed is a method of inhibiting the growth of free-living microorganisms or biofilm utilizing the above antimicrobial composition, as well as use of such antimicrobial compositions in various products including fuels, fluids, lubricants, coatings, adhesives, sealants, elastomers, soaps, cosmetics, plastic or woven or non-woven fibers, pharmaceuticals, and as preservatives for the above products.Type: ApplicationFiled: June 14, 2012Publication date: October 4, 2012Inventors: John D. Nelson, Thomas J. Palys, Jon R. Geiger
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Publication number: 20120251450Abstract: Of the many compositions and methods provided herein, one composition includes a nanoparticle having a first oxide of a first metal and a dopant that includes an ion or an atom of a second metal. A method includes a method comprising providing a plurality of nanoparticles comprising a first oxide of a first metal and a dopant that comprises an ion or an atom of a second metal; providing a diseased cell and a healthy cell; contacting the diseased cell and the healthy cell with the nanoparticle; and allowing the nanoparticle to preferentially associate with the diseased cell.Type: ApplicationFiled: April 4, 2011Publication date: October 4, 2012Inventors: Alex Punnoose, Denise Wingett
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Publication number: 20120244225Abstract: Disclosed are: Au—Ag core-shell nanorod particles wherein a cationic surfactant such as CTAB is substituted by an other compound; and a method for producing the Au—Ag core-shell nanorod particles. Specifically disclosed are Au—Ag core-shell nanorod particles which are characterized in that each of the nanorod particles comprises a gold nanorod particle that serves as the core, a shell layer that covers the surface of the gold nanorod particle and is formed from silver, and a copolymer that adsorbs on the surface of the shell layer. The Au—Ag core-shell nanorod particles are also characterized in that the copolymer is a block copolymer or graft copolymer that is obtained by polymerizing at least a polymerizable monomer (A) that has a group represented by general formula (I). In the formula, Ra represents an alkylene group having 2-7 carbon atoms.Type: ApplicationFiled: December 10, 2010Publication date: September 27, 2012Inventors: Hidenori Otsuka, Toshihiko Kurosawa, Yoshihiro Saito
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Publication number: 20120245540Abstract: According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a topical composition is provided, which can be formulated as a homogenous mixture, such as a spray, mist, aerosol, lotion, cream, solution, oil, gel, ointment, paste, emulsion or suspension or applied on a carrier material, such as a bandage, gauze, foam, sponge, hydrogel, hydrocolloid, hydrofiber, occlusive dressing, adhesive composition or scaffold. Methods for producing such a topical composition and carrier material with the topical composition applied thereto are also disclosed.Type: ApplicationFiled: March 24, 2011Publication date: September 27, 2012Inventors: Dmitry Zimnitsky, Jenny Finkbiner