Abstract: A method of inducing mineralization in a bone cell is described. The method comprises contacting a bone cell with a composition comprising nanoparticles. The nanoparticles can be single-walled carbon nanotubes, hydroxyapatite nanoparticles, TiO2 nanoparticles or silver nanoparticles. The bone cell can be an osteoblast cell. A method for increasing bone mass, bone healing or bone formation is also described which comprises administering to a subject in need thereof an effective amount of a composition comprising nanoparticles. The subject can suffer from a bone disease such as osteoporosis. The subject can suffer from a bone fracture and the method can comprise contacting bone cells near the bone fracture site with the composition. The composition can further comprise a pharmaceutically acceptable carrier.

Abstract: Ultrasound gels and methods for making ultrasound gels are disclosed herein. According to one embodiment, a gel for use with an ultrasound machine comprises glycerol and a composition. The composition in-turn comprises chlorhexidine gluconate and propylene glycol.

Abstract: A silver composition comprising silver sulfate, methods of making antimicrobial articles, particularly packaged antimicrobial articles, methods of whitening antimicrobial articles, and packaged antimicrobial articles.

Abstract: An embodiment relates to a composition comprising a noble-metal containing nanoparticle and a polymer located on a surface of the nanoparticle, wherein the polymer is a polycondensation product of a halogenated monomer. Other embodiments relate to the method of making a composition and providing antimicrobial treatment using the composition.

Abstract: A method for producing a silver-bonded antimicrobial moist wound dressing. A silver-containing compound is added to a 0.1-30% aqueous solution of an alkaline solvent to dissociate silver ions from the silver-containing compound, dissolving CMC in water or an organic solvent to obtain a CMC solution, the silver ion-containing solution is mixed with the CMC solution so that the hydrogen ions (H+) of the hydroxyl groups of the CMC are replaced by the silver ions to prepare a silver-CMC compound, the silver-CMC compound is dispersed and absorbed in a medium, and the medium is dried.

Abstract: A method of producing a hydrophilic polyurethane foam structure containing a silver salt, chosen from the group of silver sulphate, silver citrate, silver acetate, silver carbonate, silver lactate and silver phosphate, or a mixture of these salts includes the steps of (a) providing a water phase containing a surfactant, and at least one silver salt, wherein the at least one silver salt is dispersed in the water phase; (b) providing a isocyanate-terminated polyether having functionality of more than (2); (c) mixing the water phase and the isocyanate-terminated polyether, immediately transferring the resulting mixture to a mould whereby a foam structure is obtained; and (d) drying the foam structure until it has a moisture content of at most 10% (wt). The hydrophilic polyurethane foam structure produced by the method and a wound dressing containing the foam structure are also described.

Abstract: Disclosed are a solid state synthesis method of silver nanoparticles, and silver nanoparticles synthesized thereby. The method includes mixing a silver salt and a water soluble polymer acting as both a reducing agent and a protecting agent to produce a solid mixture, and milling the solid mixture by a high-speed vibration milling process to form silver nanoparticles within the water soluble polymer. According to the present invention, silver nanoparticles can be easily and simply produced in a solid state through high speed vibration milling, thereby reducing costs for industrial production and transportation of silver nanoparticles. In addition, the synthesized silver nanoparticles can be used for a long time since the silver nanoparticles are stable in a solid state for 1 year or more.

Abstract: The present invention includes antimicrobial silver-containing compositions that are effective in treating Erwinia species bacteria. These compositions are particularly effective for treating plants susceptible to Erwinia species infections.

Abstract: A composition for promoting the formation of clots in blood comprises a zeolite and a binder. The zeolite is adjusted to have a specific moisture content. Processes by which the moisture content is adjusted include drying, re-hydrating, and combinations of drying and re-hydrating. A method of forming the composition comprises the steps of providing a zeolite and adjusting the moisture content such that upon application of the composition to a wound, a heat of hydration is reduced and heat transferred to the wound is reduced. A method of clotting blood flowing from a wound comprises the steps of applying the zeolite to the wound and maintaining the zeolite in contact with the wound for a predetermined amount of time, the zeolite having an adjusted moisture content and being capable of producing a controllable exothermic effect on the wound.

Abstract: A method for producing a complex of metallic nanoparticles and inorganic clay and an organic promoter, wherein the organic promoter is ethanolamine, for example, monoethanolamine (MEA), diethanolamine (DEA) or triethanolamine (TEA). The metallic nanoparticles produced by this method can be stably and uniformly dispersed without adding other reducing agent or dispersant.

Abstract: A liquid mixture that forms a film on a surface which inhibits the life functions of bacteria. In particular the film may include copper or silver, or a combination thereof, to provide an environment hostile to bacteria and other infectious organisms.

Abstract: A method of forming and resulting nano-structured composite includes atomizing a mixture of an amount of each of aminopropyltriethoxysilane, AgNO3, DI water, and ethanol in a carrier gas; heating the atomized droplets at a selected temperature for a time sufficient to reduce the Ag to its elemental form in a silica matrix; and outputting the nano structured composite particles. A predetermined heating time is from about 0.01 to about 40 seconds and a selected heating temperature is from about 200 to about 800° C. The nano structured composite includes a plurality of nano particles at a contact surface of the composite, dispersed throughout and at a contact surface of the composite, or dispersed throughout the composite.

Abstract: A biocompatible putty formulation suitable for insertion within chronic and acute wounds of humans and animals, the formulation containing a topical antibiotic, a biocompatible humectant, a biocompatible viscosity-building agent, and at least 5% water, by weight, the humectant and the viscosity-building agent intimately mixed within the formulation, the formulation adapted whereby the formulation remains a solid over the entire temperature range of 20° C. to 35° C.

Abstract: The present invention relates to a preservative or antimicrobial compositions which comprise low concentrations of botanical extracts, in synergistic combinations with alkanediols in a solvent system, optionally with fruit acids. Additionally, the present invention relates to a preservative or antimicrobial compositions which comprise a silver compound, an essential oil or individual constituent, one or more zinc salts, and one or more alkanediol. The compositions of the invention may be used in personal care products including wound care products or in veterinary use. Preferably, the compositions of the invention have little or no human-detectable fragrance.

Abstract: In one embodiment, an antiviral material includes at least one microparticles selected from tungsten oxide microparticles and tungsten oxide composite microparticles. The microparticles have an inactivation effect R of 1 or more expressed by [R=logC?logA], when there is evaluated a virus titer by inoculating on a specimen to which the microparticles are adhered, at least one virus selected from a low pathogenic avian influenza virus (H9N2), a high pathogenic avian influenza virus (H5N1) and a swine influenza virus, and irradiating the specimen with visible light having a wavelength of 380 nm or more and illuminance of 6000 1× for 24 hours.

Abstract: Extracorporeal systems and methods for treating blood-borne diseases in a subject or for developing drugs to treat blood-borne diseases include various environmental and treatment modules that can be tailored to a specific disease or infection. In certain embodiments of the systems and methods, a blood sample is treated with hydrostatic pressure, a pulsed electrical field, a pharmaceutical agent, microwave, centrifugation, sonification, radiation, or a combination thereof, under environmental conditions that are effective for the treatment.

Abstract: The present invention relates to pesticidal mixtures, compositions and uses thereof comprising a component (A) and a component (B), wherein components (A) and (B) are: (A) a carboxylic acid amide fungicide; and (B) a benzamide fungicide; with the proviso that the mixture does not comprise: 1). fluopicolide and mandipropamid and clothianidin; or 2). fluopicolide and mandipropamid and imidacloprid; or 3). fluopicolide and mandipropamid and thiamethoxam. The invention also relates to mixtures, compositions and uses thereof wherein component (A) is metalaxyl-M and component (B) is a benzamide fungicide.

Abstract: A wound dressing comprising one or more absorbent elements capable of absorbing wound exudates, a non-steroid anti-inflammatory pain-killing agent and a complex of silver ion and a transitional element of group IV of the periodic system of elements.

Abstract: The invention concerns antiseptic ointments for external application comprising, as a basis, pharmaceutical Vaseline or a mix of pharmaceutical Vaseline with lanoline, and, as the antiseptic agent, a dispersed bentonite powder intercalated by one or more metal ions selected in the group consisting of Ag+, Cu2+, Zn2+. In addition the ointment contains an etheric vegetable oil. More precisely the active antiseptic agent may be: a dispersed bentonite powder intercalated by ions of Ag+ or by ions of Cu2+ or by a mix of said bentonites. According to an anternative the antiseptic dispersed bentonite powder may be intercalated by ions of Ag+ and Zn2+ or by ions of Cu2+ and Zn2+ or by ions of Ag+, Cu+ and Zn+. In any case the total content of metals in the composition of ointment is comprised between 0.05-0.5%. The ointments according to the invention are biologically compatible with various integuments of humans and animals and provide a prolonged antiseptic action at low expenses.

Abstract: The invention relates to a method of managing a tumor of an animal subject comprising imaging the tumor by delivering a dosage of imaging nanoparticles to the tumor site, the imaging nanoparticles consisting of positively charged chitosan, optionally a zero-charge substance or bioactive agent, and a negatively charged substrate having gadolinium (Gd) chelated to the negatively charged substrate.

Abstract: A new composite comprises (a) 10.1-99.9% by weight of elemental Ag and (b) 0.1-89.9% by weight of ZnO, wherein the sum of (a) and (b) makes 90% or more by weight of the composite and wherein the elemental Ag has a primary particle size of 10-200 nm and/or the ZnO has a primary particle size of 0.1 to below 50 ?m and/or the composite has a particle size distribution of 0.1-50 ?m and/or a BET surface area of 10-100 m2/g. The novel composite may be obtained by the steps (i) mixing a first mixture of at least one Ag-salt with a second mixture of at least one Zn-salt thereby forming a third mixture of Ag- and Zn-salts, (ii) adding the third mixture to a mixture of a carbonate source, (iii) co-precipitating of the Ag- and Zn-carbonates formed in step (ii), (iv) washing of the Ag- and Zn-carbonates and (v) thermal decompositing of the Ag- and Zn-carbonates.

Abstract: A virus inactivating sheet is provided that can inactivate viruses adhering thereto even in the presence of lipids and proteins regardless of whether or not the viruses have an envelope. The virus inactivating sheet can inactivate viruses adhering thereto and includes a sheet body, and monovalent copper compound fine particles and/or iodide fine particles that are held by the sheet body. The virus inactivating sheet can inactivate various viruses. These viruses can be inactivated even in the presence of lipids and proteins.

Abstract: A composition is able to treat plant and animal diseases and includes a therapeutically effective amount of an encapsulated ionic mineral complex and a pharmaceutically acceptable carrier. The composition may also include other inert ingredients, botanical extracts and vitamin and mineral supplements.

Abstract: The present invention relates to an antimicrobial material consisting of particles comprising an antimicrobial agent (A) and a carrier (B), wherein: the antimicrobial material is a granular material; at least 90% w/w of the particles have a particle size in the range of from 1.0 mm up to and including 8.0 mm measured according to the method DIN 66165-1/-2; at least 90% w/w of the particles have an aspect ratio R, equal to or lower than 8; the antimicrobial agent (A) comprises elemental silver nanoparticles; the antimicrobial agent (A) is present in an amount in the range of from 0.001% w/w up to and including 2% w/w on antimicrobial material; the carrier (B) is a polymer comprising a polyamide; the carrier (B) is present in an amount in the range of from 98% w/w up to and including 99.999% w/w on antimicrobial material. The invention further relates to an article comprising the granular antimicrobial material, a device comprising the granular antimicrobial material or the article.

Abstract: Nanoparticles such as nanosilver or nanocopper are used for the construct of anti-microbial articles and accessories for vehicles, trains, and/or airplanes. The anti-microbial articles include a distal section, proximal section and a primary section. The primary section further comprises nanosilver or nanocopper. In one embodiment the nanoparticles comprise a plurality of nanosilver fibers braided, woven or otherwise interwoven to form at least a portion of the primary section. Alternatively, the nanosilver is comprised of a coating over the primary section. The entire article may include the nanosilver composite. The anti-microbial article for vehicles, train, and/or airplanes includes steering wheels, steering wheel covers, gear shifts, gear shift covers, head rests, head rest covers, seats, seat covers, infant seats, infant seat covers, rugs or mats, neck pillows, door handles, door handle covers and travel blankets.

Abstract: The present invention relates to antibacterial composition containing silver complexes, antibacterial treatment methods using the same and antibacterial formed article, in which the antibacterial composition containing silver complexes is economical, not wearing off due to washing, cleaning, rubbing, etc., firmly combined to improve durability and antibacterial effect, and applicable to various products due to great solubility and stability.

Abstract: Gelatinous foam, coated paper, fabric, and polymer materials combined with the Colloidal Silver or Gold additive to formulate products with anti-microbial surfaces which will then be installed through a process determined by the owner/operator of a multi-person/multi-use facility (with input from the end user) to create anti-microbial areas within the facility. Embodiments of the present invention can be formed from polymer materials with silver or gold additives for creating bacteria-free anti-microbial areas, known as a Clean Zone™, in multi-use or multi-person facilities, such as gyms, hotels, hospitals, doctors' offices, food courts, restaurants, cruise ships, buses, and airplanes. The various embodiments include coated polymer sheets, polymer trays, bamboo and/or cotton towels, rugs and fabric, polymer foam, or polymer mats containing nano-silver or nano-gold in an scheduled and organized manner (with input/requests from the customer) to create permanent or semi-permanent anti-microbial surfaces.

Abstract: Gelatinous foam, coated paper, fabric, and polymer materials combined with the Colloidal Silver or Gold additive to formulate products with antimicrobial surfaces. Some embodiments of the present invention can include gelatinous materials selected from a group consisting of thermosetting polymer, Styrene-Ethylene-Butadiene-Styrene polymer (SEBS), Thermoplastic Elastomer (TPE), and Polyurethane (PU) gelatin with and without a raised geometry on an outer surface and in any shape. The various embodiments include coated polymer sheets, polymer trays, bamboo and/or cotton towels and fabric, polymer foam, or polymer mats containing nano-silver or nano-gold in an scheduled and organized manner (with input/requests from the customer) to create permanent or semi-permanent anti-microbial surfaces.

Abstract: The present invention is directed to an antimicrobial composition, comprising pyrithione or a pyrithione complex; and a zinc or copper or silver source selected from the group consisting of zinc or copper or silver salts, oxides, hydroxides, sulfates, chlorides, metals, and combinations thereof; wherein the weight ratio of the zinc or copper or silver source to the pyrithione or the pyrithione complex is in the range from about 1:300 to about 50:1, and wherein the antimicrobial composition has an enhanced biocidal effect against a variety of free-living microorganisms or biofilms. Also disclosed is a method of inhibiting the growth of free-living microorganisms or biofilm utilizing the above antimicrobial composition, as well as use of such antimicrobial compositions in various products including fuels, fluids, lubricants, coatings, adhesives, sealants, elastomers, soaps, cosmetics, plastic or woven or non-woven fibers, pharmaceuticals, and as preservatives for the above products.

Abstract: Unique methods for preparing and producing non-toxic, liquid customized preservative substance formulations that may be used as embalming, sterilizing, disinfectant, preservative, mold destroying and fungus extermination solutions. These substances can: (a) safely resist or retard natural destructive processes; (b) save or keep things from decaying, decomposition, deterioration, spoiling, putrefication or fermentation; (c) continually prevent or inhibit unwanted microbial growth; and, (d) be used as embalming medical devices to significantly retard the carious destructive processes of nature with anti-microbial properties. These formulations forestall, prevent and inhibit undesirable chemical/biological changes, microbial/bacterial actions, plus retard decomposition or other negative changes. The formulations are comprised of ultra-fine minute nano-sized colloidal silver particles in pure distilled water resulting in stable suspended preparations.

Abstract: The present invention relates to galvanic particulates, their methods of manufacture and uses in treatments are described. The galvanic particulates may be binary or tertiary galvanic particulates, for example, containing multiple layers or phases of conductive materials.

Abstract: According to one embodiment, a coagulant comprising calcium nitrate and an antimicrobial agent is disclosed. The coagulant may be used in the molding process to releasably bond the substrate material to the mold and to bond to the antimicrobial to the substrate material.

Abstract: Medical implants such as bone graft substitutes that include one or more cations are delivered in a local environment to promote osteogenesis. Zeolite loaded with a metal cation in combination with an implant such as a bone graft substitute can be used as an implant in the body to regulate protein transcription and translation. Also disclosed are methods of promoting osteogenesis in a patient in need thereof, methods for modulating bone formation and mineralization by implanting in a patient a medical implant comprising ion-exchangeable cations, and methods of regulating BMP gene expression in bone cells in a patient by controlling the delivery of certain cations through ion-exchange via a zeolite incorporated in a bone substitute implanted in a patient so that BMP gene expression can be upregulated or downregulated appropriately.

Abstract: A silver composition comprising silver sulfate, methods of making antimicrobial articles, particularly packaged antimicrobial articles, methods of whitening antimicrobial articles, and packaged antimicrobial articles.

Abstract: An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same.

Abstract: The present invention relates to topical compositions containing choline alfoscerate for use in maintaining and restoring the integrity of the mucous membranes.

Abstract: [Object] The object of the invention is to provide a granular antimicrobial agent for water processing which has sufficient water permeability and antimicrobial effect, and the effective duration of which can be readily ascertained when used as a water-processing antimicrobial agent in the home. [Means for Solving the Problems] A granular antimicrobial agent for water processing which has a solubility at 25° C. of preferably 0.1 mg/g·L·hour to 1 mg/g·L·hour, comprises 0.5 wt % to 4 wt % of Ag2O, 2 wt % to 10 wt % of K2O, 35 wt % to 50 wt % of SiO2, and 40 wt % to 55 wt % of B2O3, and has a semispherical or conical shape in part was found. In addition, the inventors found that the antimicrobial agent is highly suitable for use in various kinds of water processing, particularly, the antimicrobial treatment of water used for washing, and completed the invention.

Abstract: Anti-spoilage inserts and methods are provided for inhibiting the spoilage of liquid foods.

Abstract: The invention is related to compositions which can be used as dermal formulations for supporting the skin to restore normal conditions in case of e.g. irritated skin, or to support medical therapy of skin with atopic dermatitis symptoms, atopic dermatitis, psoriasis or related diseases (e.g. accompanied by distorted barrier function of the skin and microbial load). The compositions of the invention can be used for dermo-cosmetic products but also for pharmaceutical/-medical products, depending on the composition and the additional actives incorporated (cosmetic actives or drugs). The invention is based on the synergistic effect of metallic particles, in particular silver particles (such as microsilver, nanosilver) and lipid particles (lipid nanoparticles or lipid microparticles). As alternatives to silver particles, other metallic particles (e.g. zinc, copper) or nanocrystalline actives can be incorporated (e.g.

Abstract: This invention relates to high surface area materials, such as nanoparticles, that are coated with metal ions. These modified nanoparticles have active sites that bind various gases and/or odorous compounds, thereby removing these compounds from a medium such as air or water. Metal ions are adsorbed onto the surface of the nanoparticle and bound strongly to the surface. By selection of the metal ion, specific gaseous compounds and/or odorous compounds can be targeted and removed efficiently and effectively from both aqueous phase and from the air. The modified nanoparticles are useful in numerous article of manufacture for industrial and consumer use.

Abstract: Methods for processing substrate surfaces carrying coatings comprising a metal are disclosed. The methods involve providing a substrate surface having a coating comprising a metal, and exposing the substrate surface to a mixture including an oxidizing agent and an anion.

Abstract: Transdermal compositions containing castor oil are described. The compositions comprise ricinoleic acid and a transdermal vehicle with optional additional agents. One optional additional agent is an adrenergic drug which may cause the ricinoleic acid to penetrate the skin more deeply and have a longer lasting effect. The compositions can be used for treating a variety of ailments traditionally treated with castor oil or castor oil packs, without the mess and inconvenience of using castor oil packs.

Abstract: A method of preparing antimicrobial-containing polymeric products is provided, the method involving electrospinning a dispersion comprising a dispersible polymer, a fiberizing polymer, and one or more antimicrobial agents. The electrospun material is heated to remove solvent and the fiberizing polymer, giving a nonwoven polymeric material having antimicrobial agent incorporated therein. The material can be in the form of, for example, a non-woven sheet, tube, or covering.

Abstract: A method and compositions for wound care management comprising a dressing comprising a three-dimensional body of glass-based fibers comprising 40 to 80 weight % B2O3, wherein at least 25 wt. % of the fibers have a diameter between 200 nm and 4000 nm, and a length:width aspect ratio of at least 10. The glasses may also be used for wound care as fibers formed into sutures, as particles in surgical glue to close a wound, or as particles in an ointment or cream to apply to a wound. The compositions may comprise glass formers P2O5 and/or SiO2; alkali oxides selected from Li2O, Na2O, K2O, and Rb2O; and/or alkaline earth oxides selected from MgO, SrO, BaO and CaO. The compositions may further comprise 0.05 to 10 wt. % of one or more trace elements selected from Ag, Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn.

Abstract: A new, novel and useful disinfection and purification system comprised of organic compounds in synergistic action with selected metal ions and method of manufacture and use. One of the benefits that is derived from this system is the ability to quickly and easily treat a surface, fluid or medium for disinfection of bacteria, fungi, viruses, algae and protozoans, with a non-toxic, non-chlorinated mixture that effectively kills all such organisms in minutes or hours. The disinfection and purification system remains effective for long periods of time maintaining its disinfection capacity making it highly effective for stored or transported mediums such as potable drinking water. The disinfection and purification system may be incorporated with carbon block or membrane filters to disinfect filtered liquids such as water to render it potable.

Abstract: The use of microbial nanoparticles to stabilize antifungal activity is described. The preferred silver and gold nanoparticles are formed from various categories of microbes like bacteria, fungi and actinomycetes. The silver and gold nanoparticles synthesized from microbes, which can efficiently work as biocontrol/biofertilizer agent in field. The stabilized antagonistic activities of the microbes can be used for many other purposes with respect to the microbe selected for nanoparticle synthesis. Here the selected microbes were an indigenous organisms isolated from the tea fields that can control various diseases, individually and in combination with other microbe as biofertilizer.

Abstract: A method for producing fibers with improved color and anti-microbial properties is described. One embodiment includes a method for generating a halogen stable anti-microbial synthetic fiber, the method comprising creating a mixture that includes a polymer, an anti-microbial agent, and a cationic pigment, and extruding the mixture to form an anti-microbial synthetic fiber.

Abstract: The present invention provides a composite of spherical silver nanoparticles and layered inorganic clay. This composite can effectively inhibit the growth of silver-resistant bacteria. The layered inorganic clay serves as carriers of the silver nanoparticles and disperses them. The composite has a particle size of about 5 nm to 100 nm. The silver nanoparticles can be dispersed in an organic solvent or water.

Abstract: There is provided an artificial marble that includes antimicrobial substance, wherein the antimicrobial substance comprises less that about 0.002% (dry weight) of the artificial marble composition.

Abstract: A method and kit for eliminating a psoriatic lesion involves removal of loose psoriatic scales if present, and moistening remaining scales to a depth to or just above epidermal tissue underlying the scales. The hydrated scales are then contacted with a dry composition of from about 50% to about 95% silver nitrate using a specially configured applicator such that a portion of the moisture of the hydrated psoriatic scales will be absorbed into the dry composition so as to dissolve an outer layer of the silver nitrate into a solution. The solution will then be absorbed into the psoriatic scales to the depth of the moistening thereof to chemically cauterize the moistened scales. The method can be repeated until elimination is achieved. Cauterization of surrounding and underlying tissue is undesirable, and if contacted by moisture, dehydration can be allowed, and the lesion rehydrated as necessary.