Abstract: There is provided a treatment product (1) comprising a patch (3), said patch (3) comprising a polysiloxane as a treatment agent, and wherein the patch (3) is arranged such that it can be removeably adhered to a user's skin. Also provided are other treatment products, the use of polysiloxane for manufacturing a medicament and the use of polysiloxane to treat a cutaneous condition.

Abstract: The present invention is directed to a composition containing: (a) at least one tackifier component having a glass transition temperature (Tg) of greater than about 20° C.; (b) at least one film former chosen from a propylphenylsilsesquioxane resin having a molecular weight of from about 2,000 to about 30,000 and comprising at least about 70 mole % propyl siloxy units and at most about 30 mole % phenyl siloxy units, and a propylsilsesquioxane wax substituted with alkyl units having at least 30 carbons; (c) a liquid fatty phase comprising at least one volatile hydrocarbon compound; (d) at least one colorant; (e) optionally, water; and (f) optionally, at least one emulsifier. Also disclosed is a method of making up keratinous substrates involving applying the above composition onto the keratinous substrates.

Abstract: The invention relates to polysiloxanes of the general formula (I) [M?Dn]3T, ??(I) in which: M? is XSiY2O1/2 D is SiY2O2/2 T is SiZO3/2 and a process for the preparation thereof and their use as additives in aqueous surfactant-containing formulations.

Abstract: [Problems to be Solved] To provide an oily solid cosmetic having superior shaping property as well as skin repair effect, skin moisturizing effect and cosmetic persistence as compared to the prior art products. [Solution means] An oily solid cosmetic comprising a polyamide resin, a branched alcohol and a divalent alcohol.

Abstract: Novel biodegradable phosphoester polyamines are disclosed. The biodegradable phosphoester polyamines may be utilized as cross-linkers for sprayable compositions which may be used as tissue adhesives or sealants.

Abstract: Disclosed herein is a dermal filler composition. The composition includes polymethylmethacrylate (PMMA), cross-linked dextran, hydroxypropyl methylcellulose (HPMC), and physiological saline or distilled water. The composition rapidly restores volume at application sites by injection, does not require pre-testing, such as allergic skin testing, because it does not cause severe allergic reactions, is cheap, and is not easily degraded or absorbed in the body, thus ensuring a long-lasting volume augmentation effect. Due to the characteristics described above, the composition facilitates volume correction requiring a large amount (20 cc or greater) of dermal filler such as in augmentation phalloplasty.

Abstract: The present invention relates to a cosmetic composition intended for the care and/or make-up of keratinous substance(s) comprising, in a physiologically acceptable medium, at least one compound X, one compound Y and at least one catalyst, with at least one of the compounds X or Y being a polyorganosiloxane, and said compounds X and Y being capable of reacting together by a hydrosilylation reaction in the presence of a catalyst, with at least one compound from the compounds X and Y being present in said composition in an encapsulated form, said catalyst being combined with at least one of said encapsulated compound X or Y.

Abstract: The use of terpolymers, obtainable by free radical copolymerization of (a) at least one anhydride of a C3-C10-dicarboxylic acid, (b) at least one 1,1-di-(C1-C3-alkyl)-substituted C4-C8-olefin, (c) polyisobutene having an average molecular weight Mn in the range of from 200 to 10 000 g/mol and, if appropriate hydrolysis, for the preparation of aqueous emulsions or dispersions of hydrophobic substances with the use of not more than 2% by weight of further emulsifier, based on the total aqueous emulsion or dispersion.

Abstract: Novel compositions comprising minoxidil, a thickening agent, and a pharmaceutically acceptable solvent are presented. Also presented is a process for making a novel gel composition comprising minoxidil, and methods for using the novel compositions for treating and preventing hair loss in a region of a patient.

Abstract: The present invention relates to a hyaluronidase inhibitor containing poly-gamma-glutamic acid (PGA) as an active ingredient, a composition for maintaining skin elasticity and a composition for improving allergy, wherein each of the compositions contains PGA as an active ingredient. The inventive compositions containing PGA are effective in maintaining skin moisturization and skin elasticity by effectively inhibiting the activity of hyaluronidase which is an enzyme that degrades hyaluronic acid present in the skin dermis. Also, the compositions can relieve allergic symptoms by inhibiting the permeability of inflammatory cells.

Abstract: The invention describes DOPA functionalized, branched, polyalkylene oxide materials that are useful as adhesives.

Abstract: An adhesive composite composition is provided including one or more polymerizable monomers and one or more metal stearates. The one or more polymerizable monomers may be a cyanoacrylate monomer. The adhesive composite composition may further comprise a plasticizer, an initiator, a rate modifier, a stabilizer, a colorant, a heat dissipating agent, or other additives. Methods for the application of the adhesive composite compositions to living tissue are also provided. The adhesive composite composition provides an adhesive composite material upon polymerization which is a polymer matrix entrapping the metal stearate. Polymerization of the adhesive composite composition at a site on living tissue provides an adhesive composite material which promotes microcirculation and tissue growth at the site of application of the adhesive composite composition.

Abstract: A process for manufacturing polymers of glycerin and hydroxyl fatty acids, for example, polyglycerol polyricinoleates, which mix a polyglycerol with a hydroxyl fatty acid directly to form a reaction mixture, and then heat the reaction mixture to a temperature sufficient to cause it to polymerize through an esterification mechanism until the reaction mixture reaches a desired acid value.

Abstract: A composition for dry cow udder protection includes a bimodal interpenetrating polymer system having both cationic and anionic functionalities and capable of forming a stable aqueous solution and ionic bonds between polar chains. The bimodal inter-penetrating polymer system, preferably, includes two acrylate copolymers, Polyacrylate-18 and Polyacrylate-19. The bimodal interpenetrating polymer system is approximately 20% to approximately 40%, by weight, of the aqueous solution, and preferably has a thixotropic viscosity of from approximately 500 cps to approximately 5,000 cps, as measured with a Brookfield Viscometer at 20 rpm with a #3 spindle. The composition, as part of an aqueous solution, is applied to the region of a cow teat to be protected and allowed to dry, resulting in a water-insoluble protecting film.

Abstract: An object of the present invention is to provide products composed of a biodegradable raw material(s). The present invention provides a biodegradable oil absorbing film containing polyhydroxyalkanoate.

Abstract: A responsive polymeric system including a responsive polymeric component capable of undergoing a transition that results in a sharp increase in viscosity in response to a triggering effected at a predetermined body site. The system includes a solid non-ceramic reinforcing component which reinforces the polymeric component, and an aqueous-based solvent wherein the viscosity of the responsive polymeric component increases by at least about 2 times upon exposure to a predetermined trigger.

Abstract: Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.

Abstract: The present invention relates to novel amphoteric polysaccharide compounds containing aldehyde function(s) corresponding to the formula (I): P—(O—(Y)p-CAT)m in which: P represents a polysaccharide chain, the said chain hearing one or more aldehyde functions and optionally one or more groups —COOV, this group possibly being obtained during the oxidation of certain carbon atoms of a saccharide unit, Y represents a linear or branched, saturated or unsaturated, optionally hydroxylated divalent C1-C8 divalent hydrocarbon-based group comprising at least one ether and/or amine function in the hydrocarbon-based chain, or a group —Si(R)2—[O—Si(R)2]q-Z-; p is O or 1, and CAT represents an ammonium group or a cationic polymer chain obtained by grafting and polymerization of ethylenic monomers bearing an ammonium function. The invention also relates to their use in cosmetics and to compositions comprising them.

Abstract: The invention concerns polyamino and/or polyammonium/polysiloxane copolymer compounds with polyalkylene oxide units in comb-shaped arrangement, a method for producing said compounds and their use, in particular for treating textiles and other natural or synthetic textile materials.

Abstract: The invention relates to agents that are used to improve optical properties such as opacity and/or brightness of dry products based on mineral matter containing said agents. More specifically, the invention relates to a method of producing dry products based on mineral matter, in which the agents used to improve the opacity and/or brightness of said dry products take the form of controlled-structure water-soluble polymers which are obtained using a controlled radical polymerisation method employing a particular alkoxyamine as a polymerisation initiator. The invention also relates to the use of aqueous suspensions and/or dispersions of mineral matter containing said polymers for the same purpose. The aforementioned dry products comprise plastics, filled paper, dry films produced by drying a coating slip, dry films produced by drying an aqueous paint formulation or dry films produced by drying an aqueous cosmetic formulation, which contain mineral matter as well as said polymers.

Abstract: The invention relates to novel cosmetic preparations comprising an O/W emulsion, where the O/W emulsion comprises at least one amphiphilic polymer comprising one or more hydrophobic units A and one or more hydrophilic units B, where the hydrophobic units A are formed from polyisobutenes modified with terminal, polar groups, at least one component with an HLB value in the range from 8 to 20, and at least one oil and/or fat phase and water.

Abstract: A composition is disclosed comprising a particle comprising the produce produced by the contacting of a silicate and a titanium containing compound, and at least one of a peroxide containing polymer, a cosmetically acceptable carrier, or a combination thereof. Also disclosed is a method for preparing a composition, comprising a) contacting an aluminum containing compound, an alkali metal silicate, and optionally a base to provide an aluminum silicate containing solution; b) contacting the solution prepared in a) with a titanium containing compound to provide a titanium aluminum silicate; c) exposing the solution produced in a) and/or the titanium aluminum silicate produced in b) to UV radiation; and then at least one of contacting at least a portion of the product of c) with at least one peroxide containing polymer, and/or contacting at least a portion of the product of c) with a cosmetically acceptable carrier.

Abstract: A system for preparing a polyphenol containing formulation includes a first component which is a polyphenol and a second component which is the solvent system for the polyphenol. The solvent system includes water and a surfactant which is an ester of a dicarboxylic acid. The components are maintained separately from one another and are mixed prior to use. Specific compositions prepared through the use of the system include polyphenols and a solvent system based upon diaryl sulfosuccinate salts, water and optional glycols together with ancillary ingredients such as buffers, preservatives, coloring agents, fragrances, and thickeners.

Abstract: Disclosed herein is a composition for make-up and/or care of the skin comprising a fatty phase, comprising: at least one resin of number average molecular weight less than or equal to 10,000 g/mol, selected from rosin, derivatives of rosin, and hydrocarbon resins, at least one hydrocarbon block copolymer, at least one fatty substance whose melting point is greater than 25° C. chosen from waxes and pasty fatty substances, wherein said composition comprises less than 5% of volatile oil.

Abstract: A composition for use on the skin includes a carbomer, a starch, vitamins, moisturizers, an astringent, a Pluronic, dimethicone, and an aluminum compound. The composition may further include water, glycerin, emulsifiers, and surfactants. The composition provides therapeutic, conditioning, and other benefits to the skin, particularly when used on the hands, and is compatible with the use of gloves, including latex gloves.

Abstract: The invention provides decorative cosmetic and dermatological compositions comprising at least one copolymer obtained by free-radical copolymerization of A) acryloyld imethyltaurine and/or acryloyld imethyltaurates, B) optionally, one or more further olefinically unsaturated, noncationic comonomers, C) optionally, one or more olefinically unsaturated, cationic comonomers, D) optionally, one or more silicon-containing components capable of free radical polymerization, E) optionally, one or more fluorine-containing components, F) optionally, one or more macromonomers, G) optionally, the copolymerization taking place in the presence of at least one polymeric additive, H) with the proviso that component A) is copolymerized with at least one component selected from one of the groups D) to G).

Abstract: Organosilicon fine particles with polysiloxane network structure made of siloxane units of specified kinds at specified ratios and having a circular ring shape as a whole and average outer and inner diameters within specified ranges such that their difference is also within a specified range can provide antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained.

Abstract: A method for treatment or prevention of skin lesions, e.g., blisters, comprising: a) applying a liquid polymerizable foundation composition to a selected location on skin, e.g., an existing lesion or an area to be protected from formation of a lesion, b) at least partially polymerizing the foundation composition in situ to form a foundation layer, and c) applying a liquid cap formulation to the foundation layer. Also a kit for carrying out such method.

Abstract: The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.

Abstract: An eraser composition for de-flakes is disclosed. The composition comprises (i) a SEBS copolymer (styrene-ethylene-butylene-styrene) and SBS copolymer (styrene-butadiene-styrene) and TPE ethane's rubber and other compositions, and the weight percentage being 10 to 35%; (ii) organic fillers of sodium carbonate, and pearl powder, and the weight percentage being about 30 to 60%; (iii) paraffin oil of weight percentage of about 35 to 55%; (iv) palm oil, jojoba oil, linolein oil, moisturizer, deep cleanser, olive oil and weight percentage of 5 to 15%; and (v) edible food pigments, edible colorants and the weight percentage of 0.1 to 0.5%.

Abstract: Methods for stimulating proliferation of cells in the epidermis and dermis of mammalian skin are disclosed. The methods comprise the step of administering to an area of the skin a composition comprising a therapeutically effective amount of human placental alkaline phosphatase, or an active derivative. The composition can be administered topically or by injection. The invention also provides a regimen for restoring or maintaining the strength and thickness of aging skin, comprising periodically administering a composition by topical application. The invention further provides methods for stimulating proliferation of cells in the epidermis and dermis of transplanted skin. A composition for topical application is also provided by the invention.

Abstract: The invention provides a delivery system for a biologically active agent comprising a gemini surfactant in admixture with the biologically active agent in a topical formulation for treatment of skin disorders or metabolic diseases. The invention also provides pharmaceutical compositions in topical formulations comprising the delivery system as set out above, in admixture with pharmaceutically acceptable carriers, diluents, excipients, or supplements suitable for application to the skin or mucosal membrane. Methods of preparation and use are also described.

Abstract: Provided are compositions comprising a low molecular weight, non-crosslinked, linear acrylic copolymer and at least one surfactant selected from the group consisting of anionic surfactants, amphoteric surfactants, and combinations of two or more thereof, and methods of using such compositions.

Abstract: This invention relates to a highly stable, dense interpenetrated crosslinked polymer network (ICPN) containing (a) a crosslinked, network-forming primary polymer containing vinyl lactam and/or acrylic acid moieties, and (b) a secondary, optionally crosslinked, distinctly different polymer interpenetrated into the network of (a) and derived from a monomer selected from the group consisting of an acrylate and/or acrylamide monomer. The invention also relates to the oil-suspension, sequential polymerization of (a) and (b) for producing the above described interpenetrated polymeric network.

Abstract: An animal-derived lipid is disclosed that is useful as a carrying agent for anti-microbial formulations. Pharmaceutical and other preparations including Emu Oil are also described as profoundly useful components in anti-bacterial, anti-fungal, and anti-viral treatments. This lipid material is extracted from the Emu (Dromais Novae-Hollandiae), an indigenous bird of Australia and New Zealand. Therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain, comprising a supernatant or filtrate of said culture suitable for topical application to the skin or mucosal membranes of a mammal are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. Additionally, the aforementioned therapeutic composition may also include an anti-microbial, anti-mycotic, and/or anti-viral agent.

Abstract: The invention relates to the preparation of placental growth factor (PLGF)-comprising therapeutic and cosmetic compositions capable of increasing angiogenesis of the cutaneous, subcutaneous and internal organ connective tissue. Such compositions are suitable for the treatment of pathological or natural states benefiting from the formation or regeneration of new vessels of the cutaneous compartment, such as scleroderma, its various manifestations, skin aging or loss of hair.

Abstract: A cosmetic composition is provided which includes a high level of glycerin, a copolymer which is preferably a C10-C18 acrylates crosspolymer, and a crystalline gel structurant comprising a surfactant and co-surfactant, the structurant having an enthalpy ranging from about 2 to about 15 Joule per gram, wherein the composition has a normal force of from about +5 to about +50 grams thereby achieving a silky sensory feel on skin, the glycerin to copolymer being present in a weight ratio ranging from about 350:1 to about 10:1. Advantageously, the composition has a SkiCon Value ranging from about 10 to about 80.

Abstract: The invention relates to compounds for topically influencing the activity of dipeptidyl peptidase of the general formula wherein A is an amino acid having at least one functional group in the side chain; B is a chemical compound covalently bound to a functional group of the side chain of A, chosen from the group consisting of (a) oligopeptides having a chain length of up to 20 amino acids, (b) homopolymers of glycine consisting of up to 6 glycine monomers, and (c) polyethylene glycols having molar masses of up to 20 000 g/mol; and C is a group amide-bonded to A chosen from the group consisting of thiazolidine, pyrrolidine, cyanopyrrolidine, hydroxyproline, dehydroproline or piperidine.

Abstract: The use of collectins and/or surfactant proteins for the treatment and prevention of ocular disease.

Abstract: Film-forming compositions, as well as methods of making and using, wherein the compositions include an optional active agent, water, a surfactant, and a water-soluble or water-dispersible vinyl polymer comprising amine group-containing side-chains and a copolymerized hydrophobic monomer; wherein the amine equivalent weight of the polymer is at least about 300 grams polymer per equivalent of amine group.

Abstract: Dried hemoactive materials comprise both a cross-linked biologically compatible polymer and a non-cross-linked biologically compatible polymer. The cross-linked polymer is selected to form a hydrogel when exposed to blood. The non-cross-linked polymer is chosen to solubilize relatively rapidly when exposed to blood. The non-cross-linked polymer serves as a binder for holding the materials in desired geometries, such as sheets, pellets, plugs, or the like. Usually, the cross-linked polymer will be present in a particulate or fragmented form. The materials are particularly suitable for hemostasis and drug delivery.

Abstract: The invention concerns the use in a cosmetic composition of at least a poly-aminoacid of general formula (I) in which X is —O—, —S— or —NR3; R1 represents in particular a hydrogen atom or a C1-C40 alkyl radical; R2 represents in particular a hydrogen atom or an optionally substituted alkyl radical; R3 represents a hydrogen atom or an alkyl radical; R4 represents a hydrogen atom or a radical such as NH2, OH, SH, —CHOHCH3, —CONH2; n is a number greater than 1 such that the poly-aminoacid derivative molecular weight ranges between 200 and 200000.

Abstract: The invention relates to a physiologically acceptable composition, in particular a cosmetic composition, containing at least one liquid fatty phase comprising at least one structuring polymer comprising a polymer skeleton having hydrocarbon-based repeating units containing at least one hetero atom, and and at least one gelling agent for the said fatty phase, the liquid fatty phase, the structuring polymer and the gelling agent forming a physiologically acceptable medium. This composition may be in the form of a stick of lipstick which is stable, which does not exude and whose application produces a glossy deposit with good staying power over time.

Abstract: The invention concerns an active principle with instant skin-tightening effect useable in cosmetics, the method for obtaining same and compositions comprising said active principle. The source material consists of a white almond press cake.

Abstract: The invention relates to methods and materials involved in diagnosing and treating autoimmune conditions. In particular, the invention relates to methods and materials involved in diagnosing arthritis conditions that are accompanied by an NADPH oxidase deficiency, methods and materials involved in treating, preventing, or delaying the onset of arthritis conditions that are accompanied by an NADPH oxidase deficiency, and methods and materials involved in identifying agonists and antagonists of NADPH oxidase activity.

Abstract: A method for convenient, controlled wound closure of an eye, the skin, internal organs and other soft tissue which comprises administering to the wound a sterile, body compatible photopolymerizable acrylate or methacrylate adhesive, and exposing the applied adhesive to light.

Abstract: A gel composition and cosmetic composition and the like that can excel in pigment and/or filler uniformity and stability and can have a good outer appearance even when further comprising a relatively large amount of pigments. A gel composition is formed by combining at least one ingredient chosen from pigments and fillers, wherein the at least one ingredient has been surface-treated by at least one water-repellent oil-repellent agent, and at least one gelling agent comprising at least one polyacrylamide-based polymer.

Abstract: The invention encompasses bodywashes containing an additive. The additive may contain a sunscreen. The additive may contain 2, 3, or more than three sunscreens. Optionally, one or more of the sunscreens may be encapsulated. The invention further encompasses methods of making and using bodywashes containing an additive, e.g., an additive containing a sunscreen.

Abstract: The invention encompasses additives for addition to a bodywash, where the additives contain one or more sunscreens, and where a bodywash which contains the additive imparts to the skin an SPF of at least about 2, in some cases at least about 5, or 10, or 15. Also described are methods of making and using the additives.

Abstract: A topical composition comprising an antiinflammatory glucocorticoid and a nucleoside analogue antiviral agent in a pharmaceutical carrier characterized in that the carrier comprises about 15 to about 25 weight % propylene glycol and about 10 to about 25 weight percent isopropyl C12–C22 alkanoic ester. The compositions have utility in the treatment or prophylaxis of herpesvirus infections and exhibit superior antiviral and therapeutic efficacy and an improved shelf life.