Abstract: A ferulic acid derivative represented by the general formula (1); a process for preparing a ferulic acid derivative represented by the general formula (1), comprising reacting ferulic acid or an ester thereof represented by the general formula (2) with a dihalomethane represented by the general formula CH2X2, wherein X is a halogen atom; and an ultraviolet light-absorbent composition comprising the ferulic acid derivative. Since the ultraviolet light absorbent composition is not only excellent in the ultraviolet light absorption but also very stable against heat, the ultraviolet light absorbent composition can be suitably used as cosmetics which especially require long-term stability.

Abstract: Resin modified elastomers, methods of making them and their uses. The method for making the elastomers comprises reacting in a diluent an ?SiH functional siloxane; a diene, diyne or ene-yne compound, a resin having the formula (R13SiO1/2)x(SiO4/2)y(R1SiO3/2)z where each R1 is independently a monovalent hydrocarbon group having 1 to 30 carbon atoms or an unsaturated hydrocarbon group having 2 to 30 carbon atoms x is ?1, y?0, z?0 and y+z?1.

Abstract: In a system for coating human skin, a chemical composition, such as a cosmetic or medical formulation, is uniformly coated over the entire body or selected parts of the body of the person being coated. The system includes atomization of the coating composition, containment of the atomized spray, and residual recovery which together yield a novel method for applying chemical compositions. An improved self-tanning composition is useful in conjunction with the system is also disclosed. Also disclosed is a plural component self-tanning system.

Abstract: A pearlescent composition containing: (a) a dialkyl ether corresponding to formula (I): R1—O—R2??(I) wherein R1 and R2 independently of one another represent linear or branched alkyl and/or alkenyl groups having from 12 to 22 carbon atoms; (b) a cationic polymer; and (c) an emulsifier selected from the group consisting of a fatty acid-N-alkyl polyhydroxyalkyl amide, an alkyl ether sulfate, a betaine, and mixtures thereof.

Abstract: The use of plant extracts, especially plant extracts with an anti-radical-type action, and a cosmetic or dermo-pharmaceutical composition containing extracts of this type. The use of at least one plant extract whose botanical genus belongs to the group formed by the following: Clidemia, Inga, Sabicea, Astrocaryum, Siparuna, Eperua, Byrsonima, Priva, Coutoubea and Goupia genera; as an active substance which has especially anti-radical-type activities, for preparing a cosmetic or dermopharmaceutical product for local, external use for the skin, the mucous membranes and/or the epithet or appendage structures.

Abstract: The present invention is directed to a method for treating symptoms associated with Restless Legs Syndrome (RLS). The method includes administering to a warm-blooded animal in need of such treatment a dose of ketamine sufficient to alleviate symptoms associated with RLS.

Abstract: A herbal healing lotion in the form of a topical composition for relieving dermatological skin conditions encountered by animals. The composition is topically applied to an affected area of skin of the animal. The topical composition contains a vehicle for distributing the active ingredients to the affected skin. The vehicle is comprised of water, carboxymethylcellulose, and colostrum which allows for the active ingredients to be received by the skin on surface and deep tissue layers. The herbal healing lotion contains no steroid or antibiotic component thereby preventing immunosuppression generally associated therewith. The herbal healing lotion combines natural ingredients in a topical composition to successfully treat dermatological conditions previously held as untreatable.

Abstract: Film-forming compositions, as well as methods of making and using, wherein the compositions include an optional active agent, water, a surfactant, and a water-soluble or water-dispersible vinyl polymer comprising amine group-containing side-chains and a copolymerized hydrophobic monomer; wherein the amine equivalent weight of the polymer is at least about 300 grams polymer per equivalent of amine group.

Abstract: The object of the present invention is to find new effects of natriuretic peptides in an ophthalmological field. The present invention provides eyedrops for promoting lacrimal secretion or for treating keratoconjunctival disorders containing the natriuretic peptide as active ingredient. The natriuretic peptides are atrial natriuretic peptides (ANP), brain natriuretic peptides (BNP) and C-type natriuretic peptides (CNP). Typical examples of the keratoconjunctival disorder are dry eye, corneal erosion and corneal ulcer.

Abstract: A method of tissue repair is provided using a biocompatible nonimmunogenic adhesive composition. The adhesive composition comprises collagen and a plurality of crosslinkable components having reactive functional groups thereon, with the functional groups selected so as to enable inter-reaction between the components, i.e., crosslinking. Kits for use in carrying out the method of the invention are also provided, as are pretreated surgically acceptable patches that have been coated with the aforementioned adhesive composition.

Abstract: The subject-matter of the present invention is a transfer-free composition comprising (a) at least one of a di-block, tri-block, multi-block and/or radial block copolymer and optionally (b) a film former or a mixture of film formers. The composition may comprise any one of a di-block, tri-block, multi-block or radial block copolymer or any mixture or blend of co-polymers. Cosmetic and pharmaceutical compositions of the invention result in a film with very good retention, good transfer resistant properties, and which does not migrate over time. The compositions have cosmetic properties which are improved in relation to those of the “transfer free” products of the prior art.

Abstract: Bioerodible poly(orthoesters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents contain hydrogen bonding groups and &agr;-hydroxy acid-containing groups.

Abstract: A cosmetic composition containing a flavonoid extract of ginko biloba leaves comprising 28 to 35% by weight of flavonoid glycosides and a maximum of 1% by weight of terpenes.

Abstract: A process for treating balding spots and a composition which when applied to areas of thinning or balding hair increases the width and visibility of the hairs within the thinning or balding area and thus obscures visibility of the scalp or skin underlying the hairs. A bonding agent helps make the spray more efficient in application, decreases undesirable overspray, and increases formula adherence to hair shafts.

Abstract: The invention relates to agents with UV radiation-absorbing and/or reflecting action comprising solid, polymorphic, crystal-line or partially crystalline lipid and/or polymer particles, for application to the skin, mucous membranes, scalp, and hair for protection against health-damaging UV radiation and for strengthening the natural skin barrier.

Abstract: An antiperspirant and/or deodorant stick composition is disclosed comprising (a) 10-60 weight % of a volatile silicone such as cyclomethicone; (b) 2-30 weight % of a low melting point wax gelling agent (particularly stearyl alcohol); (c) 1-10 weight % of a high melting point wax (such as hydrogenated castor oil); (d) 0-15 weight % of an emollient which is different from (b) and (c); (e) 0.1-10 weight % of a superabsorbent powder with little or no tack upon wetting such as starch graft homopolymers and copolymers of poly(2-propenamide-co-2-propenioic acid) sodium salt; (f) 0-30 weight % of an antiperspirant active; (g) 0-1 weight % of a dimethicone copolyol; (h) 0.01-0.5 weight % of a selected cooling agent; and (i) 0-5 weight % (particularly 0.1-5 weight %) of a fragrance; wherein the ratio of cooling agent to superabsorbent polymer is in the range of 1:50-1:2.

Abstract: The invention relates to the cosmetic use of block ethylenic copolymers of elastic nature comprising at least one rigid block having a glass transition temperature (Tg) of greater than or equal to 20° C. and at least one flexible block having a glass transition temperature (Tg) which is less than 20° C., said compolymers making it possible to obtain a film having an instantaneous recovery of between 5% and 100%. The invention also relates to cosmetic compositions containing these block ethylenic polymers of elastic nature.

Abstract: Hydrolase polypeptides having amidase activity and products capable of modulating the activity thereof are well suited for the treatment of, inter alia, dry skins and/or the signs of skin aging and/or for combating skin desquamation.

Abstract: A stable, high efficacy, low residue surfactant-free, soft solid cosmetic composition (especially an antiperspirant and/or deodorant) comprising: (a) 40-75 weight % of a volatile silicone; (b) 0.5-20 weight % of a non-emulsifying silicone elastomer; (c) 0.1-10 weight % of a of a superabsorbent powder with little or no tack upon wetting; (d) 0.01-0.

Abstract: Three solution application method for tattoo removal.

Abstract: This invention is directed to an elastomer composition produced by crosslinking a high molecular weight ≡Si—H containing polysiloxane and a diene, diyne or ene-yne compound in the presence of a diluent. The elastomer composition is suitable for use in forming personal care compositions.

Abstract: A composition containing a peripheral benzodiazepine receptor ligand for topical use in the treatment of cutaneous stress.

Abstract: A method for treating a microbial infection in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising an amino group or an ammonium group attached to the polymer backbone via an aliphatic spacer group. The polymer can be a homopolymer or a copolymer. In one embodiment, the polymer is a copolymer comprising a monomer having a pendant ammonium group and a hydrophobic monomer.

Abstract: The invention described herein relates to a therapeutic, moisturizing coating composition for elastomeric articles which is applied directly onto the skin-contacting surface of the article as part of the manufacturing process. The coating composition is thermally stable and subsequently hydrates when contacted with a moisturized skin surface to convert into a liquid “lotion” form during wearing of the article. The coating composition provides therapeutic benefits to the wearer's skin as a result of wearing the article, such as improved skin moisturization, softness of feel, improved skin elasticity and firmness, and reduced redness and irritation. The invention is particularly useful in medical gloves, including examination and surgical gloves.

Abstract: The mastitis control teat dip composition of the invention provides rapid initial kill, a useful highly pseudoplastic rheology, a barrier/film-forming capacity, a unique antimicrobial composition that is stable over an extended period of time, and unexpected long term microbial control when compared to the prior art materials disclosed in patents and used in the marketplace. The compositions of the invention are made by combining an aqueous thickened liquid composition containing the organic components which can be combined with a simple aqueous solution of a salt of chlorous acid, preferably an alkali metal chlorite. The materials can be combined, blended into a smooth viscous material and can be immediately contacted with the target animals. The compositions of the invention provide rapid initial kill, consistent long term kill and chemical and rheological stability.

Abstract: A magnetic fluid is provided comprising a block copolymer stabilizer, magnetic particles and a fluid polysiloxane medium. The stabilizer comprises an anchor block which chelates magnetic metal particles, and at least one end block which is compatible with the polysiloxane medium.

Abstract: A method of reducing the flyaway effect occurring during treatment of hair with a cosmetic composition is disclosed. According to this method an effective amount of an electrically conductive polymer is added to the cosmetic composition prior to treatment of the hair. Preferably the cosmetic composition is a shampoo or hair care composition, which contains from 0.001 to 5% of the electrically conductive polymer.

Abstract: A composition for treatment of bacterial infections of burns and wounds of the skin, comprising an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria, and a carrier for delivering said at least one lytic enzyme to the skin. The carrier may be, but is not limited to, a liquid solution applied to a bandage.

Abstract: The present invention relates to compositions and methods for administering compositions in solutions for killing adult lice and the ova comprising water, PVM/MA Decadiene crosspolymers, propylene glycol, a mixture of cetyl and stearyl alcohols, Ceteareth-20; stearalkonium chloride; benzyl alcohol; hexylene glycol; pentylene glycol, isopropyl alcohol; a mixture of spinosyn A and spinosyn D in a weight ratio of 80:20, BHT; and sodium hydroxide.

Abstract: The present invention relates to a method for treating obesity, a method for reducing the absorption of dietary fat, and a method for treating hypertriglyceridemia in a patient and to particular polymers for use in the methods or in a manufacture of a medicament. The methods comprise the step of orally administering to a mammal, such as a human, a therapeutically effective amount of one or more fat-binding polymers. The administration of the fat-binding polymer of the invention facilitates the removal of fat from the body prior to digestion, with minimal side effects and low toxicity. In a preferred embodiment, the one or more fat-binding polymers are administered in combination with one or more lipase inhibitors, for example, lipstatin and tetrahydrolipstatin.

Abstract: An antiperspirant/deodorant composition which includes a homogeneous wax-liquid matrix, minimizes syneresis or “creep,” provides smooth skin emolliency and skin conditioning, minimizes white residue left on the skin, and promotes easier shaving with less irritation, is disclosed. The compositions include an antiperspirant or deodorant active selected from antiperspirant actives, deodorant actives, perfumes, and combinations thereof, a volatile fluid (such as dodecene or cyclomethicone), a wax structurant (such as behenyl alcohol), a C6-C45 alkyl-substituted polydimethylsiloxane, and a botanical extract (preferably a water-based botanical extract, such as ginger root extract). Preferred compositions are in the form of a semi-solid composition or a solid stick composition.

Abstract: A homogeneous, transparent microemulsion comprises

Abstract: Cosmetic and personal care compositions can be manufactured using the multifunctional-additive compositions of the present invention. Such an additive preferably contains one or more particulate-based thickeners, such as a smectite clay, colloidal silica, laponite, and/or alumina, and most preferably one or more smectite clays. According to one important embodiment of the present invention, the thickener particles are co-dispersed with particles of one or more particulate UVR-filters such as titanium dioxide, zinc oxide, or SUNSPHERE (available from International Specialty Chemicals, ISP), and most preferably with the natural particulate sunscreens such as the metal oxides. Another important component of the multifunctional-additive compositions is a dispersant or surface-modifier for the foregoing particulate materials, selected from the family of polyphenolic, natural polymers such as lignosulfonates, lignins, humates, tannates, and derivatives thereof.

Abstract: Method for eradicating fleas in domestic or accommodation premises of a domestic or laboratory mammal is provided. The method involves topically applying, at least monthly, to the domestic or laboratory mammal, a parasitically effective amount of compound of Formula I.

Abstract: The invention relates to a cosmetic composition containing at least one 15-hydroxyprostaglandin dehydrogenase inhibitor and cosmetically acceptable excipients. It also relates to a method of cosmetic treatment for promoting the growth and/or preventing or delaying the loss of hair, and the use of a 15-hydroxyprostaglandin dehydrogenase inhibitor for the preparation of a composition intended for controlling hair loss and/or for promoting hair regrowth.

Abstract: A wound-covering agent containing a polymer having a group represented by formula (I) (wherein R1, R2 and R3 are the same or different and each represents hydrogen atom or C1-4 alkyl, and m is an integer of 2 to 4); a wound-covering material containing the preparation; and a method of wound healing which comprises the step of covering the wound of a subject with the wound-covering material to protect the wound.

Abstract: Dried hemoactive materials comprise both a cross-linked biologically compatible polymer and a non-cross-linked biologically compatible polymer. The cross-linked polymer is selected to form a hydrogel when exposed to blood. The non-cross-linked polymer is chosen to solubilize relatively rapidly when exposed to blood. The non-cross-linked polymer serves as a binder for holding the materials in desired geometries, such as sheets, pellets, plugs, or the like. Usually, the cross-linked polymer will be present in a particulate or fragmented form. The materials are particularly suitable for hemostasis and drug delivery.

Abstract: Pickering emulsions, which are finely disperse systems of the water-in-oil or oil-in-water type, comprising (1) an oil phase, (2) a water phase, (3) at least one type of microfine particles which a) have an average particle size of less than 200 nm, which b) display both hydrophilic and lipophilic properties, i.e. which have amphiphilic character, and are dispersible both in water and in oil and which c) have optionally been coated on the surface, (4) at least one cyclodextrin and (5) at most 0.5% by weight of one or more emulsifiers.

Abstract: Rinsable skin conditioning compositions comprising high internal phase emulsions and being substantially free of surfactant provide superior deposition on skin of conditioning agents, skin benefit agents and/or other conventional cosmetic or skin care ingredients. Such rinsable skin conditioning compositions have much improve aesthetics as well.

Abstract: The mastitis control teat dip composition having a visible indicator aspect of the invention provides a softening, soothing, smoothing, relaxing property, a rapid initial kill, a useful highly pseudoplastic rheology, a barrier/film-forming capacity, a unique antimicrobial composition that is stable over an extended period of time, and unexpected long term microbial control when compared to the prior art materials disclosed in patents and used in the marketplace. The indicator aspect provides ease of visually detecting the material on the animal skin and can indicate efficacy of the material. The compositions of the invention are made by combining an aqueous liquid composition containing the visual indicator combined with the organic components which can be combined with a simple aqueous solution of a salt of chlorous acid, preferably an alkali metal chlorite.

Abstract: Antimicrobial compositions containing one or more topically active antibiotics (e.g., Natamycin) and one or more amidoamines are described. The amidoamines enhance or supplement the antimicrobial activity of natamycin or other topically active antibiotics. The compositions are particularly useful in treating or preventing fungal infections of the eye, ear, nose and throat, as well as sterilizing these tissues prior to surgery or other medical procedures.

Abstract: The invention relates to an agent for the treatment, prophylaxis and metaphylaxis of functional and structural disorders of the skin caused by external factors. The agent contains a hyaluronic acid partially digested with a microbiological hyaluronate lyase. The hyaluronic acid fragment mixture is incorporated in different galenic formulations to which other hydrophilic and/or lipophilic active substances and/or auxiliary substances can be added. Fields of application of the invention in human and veterinary medicine relate to the treatment and/or the prophylaxis of skin damage caused by environmental factors including UV, dry skin conditions and skin ageing.

Abstract: A care or make-up composition for keratin substances such as the skin, the lips or superficial body growths, this composition containing fibers and particles of an at least partially crosslinked solid elastomeric polyorganosiloxane suspended in an aqueous phase, giving a homogeneous deposit on these keratin substances, while at the same time providing softness and a sensation of freshness; methods of using the composition; and methods of making the composition.

Abstract: A composition suitable for topical application, which contains: a liquid fatty phase, at least one coloring agent, at least 2% by weight, with respect to the total weight of the composition, of a polymer which is dispersible in the liquid fatty phase, and a polymer which is soluble in the liquid fatty phase. In preferred embodiments, the composition may be provided in the form of a cast product or of a gel containing at least one coloring material, in particular pulverulent coloring material, a dispersion of polymer particles which are stabilized at the surface in a liquid fatty phase and a fat-soluble polymer of the vinylpyrrolidone copolymer type. In addition, according to the amount of polymer, it is possible to obtain, on the lips or skin, a supple film having notable transfer-free properties while being extremely comfortable. The invention also relates to the use of this dispersion in such a composition.

Abstract: A cosmetic composition which provides a semi-permanent, crosslinked film on a keratinous substrate, comprising a film-forming polymer having functional groups capable of cross-linking upon exposure to a cross-linking agent reactive with the functional groups; a cross-linking agent reactive with the functional groups of the film-forming polymer; a dissipatable blocking agent which is operable prior to dissipation, to block the cross-linking agent from cross-linking the functional groups of the film-forming polymer, and which, after dissipation, leaves the cross-linking agent free to cross-link the functional groups of the film-forming polymer.

Abstract: A lip care moisturizing product in the form of a water-in-oil emulsion, containing at least one fatty acid ester, at least one wax, the total of said at least one fatty acid ester and said at least one wax being at least about 1.0%, liposomes containing water therein, and an emulsifier. The emulsifier is preferably a mixture of behenoyl stearate and sodium borate, and the liposomes preferably contain a mixture of water and glycerin.

Abstract: Powders treated with silicones represented by the following formula (1): R1aR2bR3cSiO(4−a−b−c)/2  (1) wherein R1, R2, R3 a, b and c are as defined herein, are suitable for use in cosmetic materials.

Abstract: The present invention relates to aqueous gel compositions comprising an odor controlling agent for deodorizing skin surfaces. Articles of manufacture and methods of deodorizing the skin using disclosed compositions are also disclosed.

Abstract: In a system for coating human skin, a chemical composition, such as a cosmetic or medical formulation, is uniformly coated over the entire body or selected parts of the body of the person being coated. The system includes atomization of the coating composition, containment of the atomized spray, and residual recovery which together yield a novel method for applying chemical compositions. An improved self-tanning composition is useful in conjunction with system is also disclosed. Also disclosed is a plural component self-tanning system.

Abstract: The invention relates to a composition containing fibers and a copolymer comprising carboxylate groups and polydimethylsiloxane groups. The composition according to the invention may especially constitute a care or make-up composition for keratin materials such as the skin, including the scalp, the lips of the face and integuments, for instance the eyelashes, the eyebrows, the nails and the hair. The invention also relates to the use of a copolymer comprising carboxylate groups and polydimethylsiloxane groups in a composition containing fibers to ensure a homogeneous dispersion of the fibers in the composition and to stabilize the composition.