Fat; Fatty Oil; Ester-type Wax; Higher Fatty Acid (i.e., Having At Least Seven Carbon Atoms In An Unbroken Chain Bound To A Carboxyl Group); Oxidized Oil Or Fat Patents (Class 435/134)
  • Lipid Production
    Publication number: 20140322771
    Abstract: The invention relates to methods for producing lipids and in particular methods for producing glycerolipids suitable for use in generating biofuels. The glycerolipids are produced through the modification of a cell so as to increase phosphatidic acid via the inhibition of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway. The invention further relates to genetically modified plants and microorganisms in which the production of glycerolipids/oil is increased.
    Type: Application
    Filed: December 9, 2011
    Publication date: October 30, 2014
    Applicant: THE UNIVERSITY OF QUEENSLAND
    Inventors: (Robert) Hongyuan Yang, Junmin Pan, Jacqueline Batley
  • MICROBIAL OILS ENRICHED IN POLYUNSATURATED FATTY ACIDS
    Publication number: 20140323569
    Abstract: The present invention is directed to microbial oils that are enriched in their content of polyunsaturated fatty acids, their esters, their acid salts, alcohols formed therefrom, and/or aldehydes formed therefrom. The present invention is further directed to compositions containing the enriched microbial oils and methods of making and using the enriched microbial oils. The present invention is also directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: July 20, 2012
    Publication date: October 30, 2014
    Inventor: Krishna Raman
  • Polypeptides Having Peroxygenase Activity And Polynucleotides Encoding Same
    Publication number: 20140322768
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: November 28, 2012
    Publication date: October 30, 2014
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Over-production of dihomo linolenic acid by a mutant strain of
    Patent number: 8871808
    Abstract: The present invention is primarily directed to a mutant strain of Parietochloris incisa, characterized in comprising a substantially reduced intracellular concentration of arachidonic acid (AA) together with a substantially increased intracellular concentration of dihomo-gamma-linolenic acid 20:3?6 (DGLA).
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: October 28, 2014
    Assignee: Ben-Gurion University of the Negev Research and Development Authority et al.
    Inventors: Zvi Cohen, Inne Khozin-Goldberg, Sammy Boussiba, Avigad Vonshak
  • ACCELERATED PROCESS FOR THE ENERGY CONVERSION OF CARBON DIOXIDE
    Publication number: 20140315266
    Abstract: The present invention relates to a process for the energy conversion of carbon dioxide, comprising the steps of culturing phytoplankton in electromagnetic bioaccelerators, producing oxygen and biomass made up of lipids, hydrocarbons and sugars from the previous step, oxidizing the hydrocarbons produced in the previous step to generate carbon dioxide and NOx and collecting the carbon dioxide and NOx from the previous step until the cultures of the first step.
    Type: Application
    Filed: March 12, 2014
    Publication date: October 23, 2014
    Inventor: Bernard A. J. Stroiazzo-Mougin
  • SYNTHESIS OF LONG-CHAIN POLYUNSATURATED FATTY ACIDS BY RECOMBINANT CELL
    Publication number: 20140314727
    Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desatorase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.
    Type: Application
    Filed: July 3, 2014
    Publication date: October 23, 2014
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Surinder Pal Singh, Stanley Suresh Robert, Peter David Nichols, Susan Irene Ellis Blackburn, Xue-Rong Zhou, James Robertson Petrie, Allan Graham Green
  • Tailored Oils Produced from Recombinant Heterotrophic Microorganisms
    Publication number: 20140315267
    Abstract: Methods and compositions for the production of oil, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants.
    Type: Application
    Filed: May 13, 2014
    Publication date: October 23, 2014
    Applicant: Solazyme, Inc.
    Inventors: Scott Franklin, Aravind Somanchi, Janice Wee, George Rudenko, Jeffrey L. Moseley, Walt Rakitsky
  • PROCESS OF PRODUCING OIL FROM ALGAE USING BIOLOGICAL RUPTURING
    Publication number: 20140315265
    Abstract: A process for production of biofuels from algae can include cultivating an oil-producing algae, extracting the algal oil, and converting the algal oil to form biodiesel. Extracting the algal oil from the oil-producing algae can include biologically rupturing cell wall and oil vesicles of the oil-producing algae using at least one enzyme such as a cellulose or glycoproteinase, a structured enzyme system such as a cellulosome, a virus, or combination of these materials.
    Type: Application
    Filed: January 27, 2014
    Publication date: October 23, 2014
    Applicant: Genifuel Corporation
    Inventor: James R. Oyler
  • Increased oil content by increasing Yap1 transcription factor activity in oleaginous yeasts
    Patent number: 8865429
    Abstract: Transgenic oleaginous yeast having increased oil content comprising increased Yap1 transcription factor activity, wherein the increased oil content is compared to the oil content of a non-transgenic oleaginous yeast, are described herein. The increased Yap1 transcription factor activity results from overexpressing a Yap1 transcription factor, by increasing the interaction between the transcription factor and a protein that is capable of activating the transcription factor, or by a combination thereof. Methods of using these yeast strains are also described.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: October 21, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Seung-Pyo Hong, Zhixiong Xue, Quinn Qun Zhu
  • PALM OIL ENRICHED IN UNSATURATED FATTY ACIDS
    Publication number: 20140303389
    Abstract: A process for producing a food oil containing at least 50% monounsaturated fatty acids from palm oil is disclosed. Fatty acids are released from palm oil glycerides, such as by fat-splitting. The free fatty acids (FFA) are separated to obtain a fraction enriched in unsaturated palm fatty acid. This fraction is subject to a condensation reaction with glycerol to form an oil comprising mainly triglycerides (triacylglycerols). The condensation reaction is catalyzed by an enzyme.
    Type: Application
    Filed: November 20, 2012
    Publication date: October 9, 2014
    Inventors: Thomas George Crosby, Marianne Linde Damstrup, John Inmok Lee, Per Munk Nielson, Craig Jordan Weitz
  • METHOD AND SYSTEM FOR PROCESSING A BIOMASS FOR PRODUCING BIOFUELS AND OTHER PRODUCTS
    Publication number: 20140302570
    Abstract: The present invention provides methods of processing a biomass, e.g., for producing lipid and non-lipid materials, by inducing autolysis of a biomass. The biomass may be generated using any species of microorganism and any available biodegradable substrate, including waste materials. The lipid and non-lipid materials are present in two separate layers of the autolysate, and they can be used to generate valuable products such as biofuels and nutritional supplements. The present invention further provides a processing apparatus useful for practicing the methods of the present invention.
    Type: Application
    Filed: June 19, 2014
    Publication date: October 9, 2014
    Inventor: Moustafa Ahmed El-Shafie
  • ALGAE STRAIN FOR BIODIESEL FUEL PRODUCTION
    Publication number: 20140302569
    Abstract: Use of an algal for biodiesel fuel selected for growing strain of production, the genus Desmodesmus wherein said strain was under high nutrient conditions and is characterized as having a determined fatty by acid nuclear methyl ester content of 2.6% magnetic resonance analysis, nitrogen content of 11.3% and a carbon content of 46.3%. Given the growth and elemental composition of this strain t the instant algal strain is of particular use as a biomass source for biofuel lipids and/or biodiesel fuel production.
    Type: Application
    Filed: July 24, 2012
    Publication date: October 9, 2014
    Applicant: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Andrew S. Gordon, Patrick G. Hatcher
  • COMPOSITIONS AND METHODS FOR ENHANCING LIPID PRODUCTION IN MICROALGAE VIA INDUCTION OF CELL CYCLE ARREST
    Publication number: 20140303386
    Abstract: Methods for enhancing lipid production in marine algae and compositions comprising lipids obtained therefrom are provided.
    Type: Application
    Filed: August 24, 2012
    Publication date: October 9, 2014
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Paul G. Falkowski, Joomi Kim
  • Production of hydroxylated fatty acids in
    Patent number: 8852885
    Abstract: Methods and compositions for the production of oil, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty acid hydroxylase, a desaturase enzyme, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: October 7, 2014
    Assignee: Solazyme, Inc.
    Inventors: Scott Franklin, Aravind Somanchi, Janice Wee, George Rudenko, Jeffrey L. Moseley, Walt Rakitsky, Xinhua Zhao, Riyaz Bhat
  • Processing biomass
    Patent number: 8852901
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, methods are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce an intermediate or product, e.g., by fermentation.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: October 7, 2014
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman, Seul-a Bae, Kelly Wallick
  • DESATURASES AND METHODS OF USING THEM FOR SYNTHESIS OF POLYUNSATURATED FATTY ACIDS
    Publication number: 20140298502
    Abstract: The amino acid and nucleic acid sequences of a ?5-desaturase enzyme and a ?8-desaturase enzyme are disclosed. The nucleic acid sequences can be used to design recombinant DNA constructs and vectors. These vectors can then be used to transform various organisms, including for example, plants and yeast. The transformed organisms will then produce polyunsaturated fatty acids. The amino acid sequences are useful for generating enzyme-specific antibodies that are useful for identifying the desaturases.
    Type: Application
    Filed: June 18, 2014
    Publication date: October 2, 2014
    Applicant: Washington State University Research Foundation
    Inventors: John A. Browse, James G. Wallis, Jennifer L. Watts
  • SUPPRESSION OF TLA2-CpFTSY GENE EXPRESSION FOR IMPROVED SOLAR ENERGY CONVERSION EFFICIENCY AND PHOTOSYNTHETIC PRODUCTIVITY IN ALGAE
    Publication number: 20140295448
    Abstract: The invention provides method and compositions to minimize the chlorophyll antenna size of photosynthesis by decreasing TLA2 gene expression, thereby improving solar conversion efficiencies and photosynthetic productivity in green microalgae, under bright sunlight conditions.
    Type: Application
    Filed: October 24, 2012
    Publication date: October 2, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Anastasios Melis, Henning Kirst
  • Genetically engineered microorganisms comprising 4-hydroxybenzoyl-coa thioesterases and methods of using the same for producing free fatty acids and fatty acid derivatives
    Patent number: 8846370
    Abstract: The described invention provides genetically engineered microorganisms, including photosynthetic microorganisms, expressing 4-hydroxybenzoyl-CoA thioesterases and methods of using the genetically engineered microorganisms for producing free fatty acids and/or fatty acid derivatives.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: September 30, 2014
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Robert Christopher Brown, Rekha Seshadri, Carlos Chavez-Torres, Weidong Xu, Toby Richardson
  • Method for lipid extraction from biomass
    Patent number: 8845765
    Abstract: A method for recovering lipids from microbial biomass, the method including providing wet microbial biomass which contains lipids to extraction without disrupting the biomass cell walls, and subsequently, extracting the wet microbial biomass with a liquid extractant at elevated temperature of at least 170° C. and elevated pressure. The combination of the temperature and pressure is such that the lipids in the cells are contacted with the extractant. Subsequently the extracted lipids are recovered from or with the extractant.
    Type: Grant
    Filed: November 8, 2011
    Date of Patent: September 30, 2014
    Assignee: Neste Oil Oyj
    Inventors: Annika Malm, Reijo Tanner, Mervi Hujanen
  • Genetically engineered microorganisms that metabolize xylose
    Patent number: 8846352
    Abstract: The invention provides methods of cultivating oil-bearing microbes using xylose as a fixed carbon source. Also provided are microorganisms that have been genetically engineered to metabolize xylose as a fixed carbon source allowing them to convert xylose into oils. Particular advantages of the processes provided herein include production of oils rather than alcohols through the microbial fermentation processes utilizing xylose.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: September 30, 2014
    Assignee: Solazyme, Inc.
    Inventors: Penelope Chua, Aravind Somanchi
  • THIOESTERASES AND CELLS FOR PRODUCTION OF TAILORED OILS
    Publication number: 20140288320
    Abstract: The invention features plant acyl-ACP thioesterase genes of the FatB class and proteins encoded by these genes. The genes are useful for constructing recombinant host cells having altered fatty acid profiles. Oleaginous microalga host cells with the new genes or previously identified FatB genes are disclosed. The microalgae cells produce triglycerides with useful fatty acid profiles.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 25, 2014
    Applicant: Solazyme, Inc.
    Inventors: George N. Rudenko, Jason Casolari, Scott Franklin
  • PROCESSING BIOMASS
    Publication number: 20140287467
    Abstract: Feedstocks, obtained at least in part from a plant material that has been modified with respect to its wild type, are processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems are described that can treat such feedstock materials, e.g., to reduce the recalcitrance of the feedstock, and use the treated feedstock materials to produce an intermediate or product, e.g., by saccharification and/or fermentation.
    Type: Application
    Filed: June 5, 2014
    Publication date: September 25, 2014
    Inventors: Marshall MEDOFF, Thomas Craig MASTERMAN
  • PHOTOSYNTHETIC PROCESS
    Publication number: 20140287458
    Abstract: The present invention provides a method of producing a photosynthetic product, the method comprising maintaining a photosynthetic plant or algal cell suspension culture, in the presence of water, light and a carbonic acid-enriched growth medium. The carbonic acid may, for example be provided by feeding the photosynthetic plant cell suspension culture with a carbonic acid solution, a solid or liquid precursor thereof, or a gaseous mixture of carbon dioxide and one or more other gases. The invention also provides a method for producing a photosynthetic product, the method comprising maintaining a photosynthetic plant or algal cell suspension culture, in the presence of water, light and a carbon source selected from carbon dioxide and carbonic acid, wherein the culture is maintained at a pH of less than 7.0, preferably 4.5 to 5.5.
    Type: Application
    Filed: May 18, 2012
    Publication date: September 25, 2014
    Applicant: NATURALLY SCIENTIFIC TECHNOLOGIES LIMITED
    Inventor: Peter Andrew Whitton
  • Process for producing unsaturated fatty acid-containing oils
    Patent number: 8841097
    Abstract: An edible oil obtained by culturing a microorganism belong to the genus Mortierella subgenus Mortierella in a medium containing a nitrogen source derived from soybean is discussed. The oils obtained have a low 24,25-methylenecholest-5-en-3?-ol content.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: September 23, 2014
    Assignee: Suntory Holdings Limited
    Inventors: Kenichi Higashiyama, Kengo Akimoto, Sakayu Shimizu
  • METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION
    Publication number: 20140273112
    Abstract: Aspects of the invention relate to methods of producing small molecules for industrial application using natural organisms and engineered organisms.
    Type: Application
    Filed: March 15, 2014
    Publication date: September 18, 2014
    Applicant: Kiverdi, Inc.
    Inventors: John S. Reed, Itzhak Kurek, Henrik Fyrst, Lisa Dyson
  • CHLOROPHYLL DEFICIENT ALGAL CELL WITH IMPROVED GROWTH AND PRODUCTION
    Publication number: 20140273113
    Abstract: Chlorophyll deficient algal strains, methods of making chlorophyll deficient algal strains, and methods of their use are provided.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 18, 2014
    Applicant: Aurora Algae, Inc.
    Inventors: Bertrand Vick, Yuen Yee Tam
  • BACTERIA AND METHOD FOR SYNTHESIZING FATTY ACIDS
    Publication number: 20140273114
    Abstract: The present invention discloses a process for increasing the production of free fatty acids at high yield (close to maximum theoretical yield), with various fatty acid compositions and various percentage of fatty acids accumulated intracellularly. This invention will enable the efficient production of other products derived from free fatty acids and/or products that can be branched out from the fatty acid synthesis pathways.
    Type: Application
    Filed: October 16, 2012
    Publication date: September 18, 2014
    Inventors: Ka-Yiu San, Mai Li
  • SYSTEM AND METHODS FOR TREATMENT OF BIOMASS PRODUCTS OR RESIDUES AND RESULTING COMPOSITION
    Publication number: 20140261075
    Abstract: The present invention is directed to a system and methods for treatment of biomass products or residues to obtain valuable adhesives and composite materials. Certain embodiments require no purification of a biomass product or residue to produce an adhesive. Certain embodiments include a treatment of post extraction algae residue configured to produce an adhesive. Advantageously, such use of post extraction algae residue adds value to alternative energy produced by extracting oil from algae.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Inventor: William Chirdon
  • THIOESTERASES AND CELLS FOR PRODUCTION OF TAILORED OILS
    Publication number: 20140275586
    Abstract: The invention features plant acyl-ACP thioesterase genes of the FatB class and proteins encoded by these genes. The genes are useful for constructing recombinant host cells having altered fatty acid profiles. Oleaginous microalga host cells with the new genes or previously identified FatB genes are disclosed. The microalgae cells produce triglycerides with useful fatty acid profiles.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Inventors: George N. Rudenko, Jason Casolari, Scott Franklin
  • Modified photosynthetic microorganisms with reduced glycogen and their use in producing carbon-based products
    Patent number: 8835137
    Abstract: This disclosure describes genetically modified photosynthetic microorganisms, including Cyanobacteria, that contain one or more mutations or deletions in a glycogen biosynthesis or storage pathway, which accumulate a reduced amount of glycogen as compared to a wild type Cyanobacterium, and which are capable of producing an increased amount of lipids and/or fatty acids. In certain embodiments, the genetically modified photosynthetic microorganisms also contain one or more exogenous genes encoding a diacyglycerol acyltransferase, a phosphatidate phosphatase, and/or an acetyl-CoA carboxylase, and which are capable of producing increased amounts of lipids or fatty acids and/or synthesizing triglycerides.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: September 16, 2014
    Assignee: Matrix Genetics, LLC
    Inventors: James Roberts, Fred Cross, Paul Warrener, Kimberly Marie Kotovic, Margaret Mary McCormick
  • INCREASING THE LIPID CONTENT IN MICROALGAE BY GENETICALLY MANIPULATING A TRIACYLGLYCEROL (TAG) LIPASE
    Publication number: 20140256927
    Abstract: The present invention relates to a method of increasing the lipid content in an organism, in particular a micro algae by modulating the activity of a triacylglycerol (TAG) lipase. The invention also concerns organisms produced by this method, or microalgae, with increased lipid content, as well as their use in industry and medicine; in particular to obtain omega-3 unsaturated fatty acids. The invention relates furthermore to a nucleic acid from Phaeodactylum tricornutum, which encodes a new TAG lipase, and its use in influencing the proportion of fatty acids, in particular the content of polyunsaturated fatty acids in biomass.
    Type: Application
    Filed: September 6, 2012
    Publication date: September 11, 2014
    Inventors: Helge Bode, Claudia Buechel, Frederik Barka, Wolfram Lorenzen
  • BIOTECHNOLOGICAL SYNTHESIS PROCESS OF OMEGA-FUNCTIONALIZED CARBON ACIDS AND CARBON ACID ESTERS FROM SIMPLE CARBON SOURCES
    Publication number: 20140256904
    Abstract: The subject of the invention is a biotechnological process for the production of ?-functionalized carboxylic acids and of ?-functionalized carboxylate esters from simple carbon sources.
    Type: Application
    Filed: August 15, 2012
    Publication date: September 11, 2014
    Applicant: Evonik Degussa GmbH
    Inventors: Steffen Schaffer, Nicole Decker, Jasmin Gielen, Harald Haeger, Thomas Haas, Markus Poetter, Hans-Georg Hennemann, Mirja Wessel, Michael Volland
  • PRODUCTION OF OMEGA-3 FATTY ACIDS FROM PYTHIUM SPECIES
    Publication number: 20140256973
    Abstract: The present invention relates to the production of a triacylglycerol oil that is produced from a Pythium species of alga. In one embodiment, the algal species contains at least about 20 weight percent total lipids and contains at least about 10 weight percent of its total fatty acids as eicosapentaenoic acid (EPA) and less than about 5 weight percent of its total fatty acids as arachidonic acid (ARA). In another embodiment, the present invention relates to various methods to produce eicosapentaenoic acid (EPA) from a Pythium species of algae. In particular, Pythium irregulare can be utilized as a viable production organism.
    Type: Application
    Filed: March 7, 2013
    Publication date: September 11, 2014
    Applicant: Algysis LLC
    Inventors: Charles L. Roe, James P. Wynn
  • NOVEL ANTIMICROBIAL COMPOUNDS AND USES THEREOF
    Publication number: 20140256812
    Abstract: The present invention relates to novel antimicrobial compounds, methods of their production as well as uses thereof.
    Type: Application
    Filed: February 12, 2014
    Publication date: September 11, 2014
    Applicant: Agency for Science, Technology and Research
    Inventors: Lianhui Zhang, Yinyue Deng, Jien Wu
  • PROCESSES FOR PRODUCING HYDROCARBON PRODUCTS
    Publication number: 20140256006
    Abstract: The present invention relates to processes for producing industrial products such as hydrocarbon products from non-polar lipids in a vegetative plant part. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
    Type: Application
    Filed: May 21, 2014
    Publication date: September 11, 2014
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Thomas Vanhercke, James Robertson Petrie, Anna El Tahchy, Surinder Pal Singh, Qing Liu
  • Multizymes comprising delta-9 elongase and delta-8 desaturase and their use in making polyunsaturated fatty acids
    Patent number: 8828690
    Abstract: Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding multizymes (i.e., single polypeptides having at least two independent and separable enzymatic activities) along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these multizymes in plants and oleaginous yeast are disclosed.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: September 9, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Howard G. Damude, Anthony J. Kinney, Kevin G. Ripp, Quinn Qun Zhu
  • Polypeptides Having Peroxygenase Activity and Polynucleotides Encoding Same
    Publication number: 20140248674
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: August 10, 2012
    Publication date: September 4, 2014
    Applicant: Novozymes A/S
    Inventors: Sara Landvik, Lars H. Oestergaard, Lisbeth Kalum
  • Method and System for Growing Microalgae in an Expanding Plug Flow Reactor
    Publication number: 20140248601
    Abstract: A method and system are provided for supporting the growth of algae cells. Initially, an inoculum of algae cells are grown in a closed bioreactor. Thereafter, the inoculum is passed into an open Expanding Plug Flow Reactor (EPFR). Growth medium is added at a plurality of locations along the EPFR. This addition is controlled in response to the growth rate of the algae cells to maintain a substantially same concentration of cells at each location in the EPFR. At all times, the medium provides sufficient nutrients to support growth and maintain a high concentration of algae cells, i.e., at least 0.5 grams per liter of medium, in the EPFR. After the desired level of growth is reached, the algae cells are transferred from the EPFR to a standard plug flow reactor wherein oil production is activated in the algae cells.
    Type: Application
    Filed: April 18, 2014
    Publication date: September 4, 2014
    Applicant: General Atomics
    Inventors: David A. Hazlebeck, Xiaoxi Wu
  • Thermostable enzyme technology for algal bioconversion
    Patent number: 8822189
    Abstract: Thermostable enzyme technology for algal bioconversion The present invention relates to thermostable enzyme systems suitable for use in the production of biofuels and bio-products from algae, and to a method of producing energy feedstocks, stocks, specifically (i) fermentable sugars and (ii) lipid fractions from algae, for the production of biofuels such as bioethanol, biobutanol and bio-oils or biodiesel, as well as other value-added biomolecules (e.g. proteins, peptides, oils, pigments, nucleic acids).
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: September 2, 2014
    Assignees: AER Sustainable Energy Limited, National University of Ireland
    Inventors: Patrick Murray, Sara Fernandes, Maria Tuohy
  • 3-hydroxypropionic acid and other organic compounds
    Patent number: 8822197
    Abstract: Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: September 2, 2014
    Assignee: Cargill, Incorporated
    Inventors: Ravi R. Gokarn, Olga V. Selifonova, Holly Jean Jessen, Steven John Gort, Thorsten Selmer, Wolfgang Buckel
  • Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
    Patent number: 8822662
    Abstract: The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerina and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: September 2, 2014
    Assignee: BASF Plant Science Company GmbH
    Inventors: Toralf Senger, Jörg Bauer, Johnathan A. Napier
  • Peroxisome biogenesis factor protein (PEX) disruptions for altering polyunsaturated fatty acids and total lipid content in oleaginous eukaryotic organisms
    Patent number: 8822185
    Abstract: Methods of increasing the amount of polyunsaturated fatty acids (PUFAs) in the total lipid fraction and in the oil fraction of PUFA-producing, oleaginous eukaryotes, accomplished by modifying the activity of peroxisome biogenesis factor (Pex) proteins, are disclosed. Disruptions of a chromosomal Pex3 gene, Pex10p gene or Pex16p gene in a PUFA-producing, oleaginous eukaryotic strain resulted in an increased amount of PUFAs, as a percent of total fatty acids and as a percent of dry cell weight, in the total lipid fraction and in the oil fraction of the strain, as compared to the parental strain whose native Pex protein was not disrupted.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: September 2, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Seung-Pyo Hong, Pamela L Sharpe, Zhixiong Xue, Narendra S Yadav, Quinn Qun Zhu
  • PROTEIN HAVING ACTIVITY TO PROMOTE FATTY ACID CHAIN ELONGATION, GENE ENCODING SAME AND USE THEREOF
    Publication number: 20140242648
    Abstract: The present invention relates to a protein having an activity to promote fatty acid chain elongation, a polynucleotide encoding the same, etc. The present invention provides, for example, a polynucleotide containing the nucleotide sequence shown in SEQ ID NO: 1 or 4, a polynucleotide encoding a protein which consists of the amino acid sequence shown in SEQ ID NO: 2, an expression vector and a transformant, each containing such a polynucleotide, a method for preparing lipids or fatty acids by using such a transformant, or a food or the like containing lipids or fatty acids prepared by such a method.
    Type: Application
    Filed: August 3, 2012
    Publication date: August 28, 2014
    Applicant: SUNTORY HOLDINGS LIMITED
    Inventor: Misa Ochiai
  • METHOD FOR OBTAINING AN OPEN PHOTOTROPHIC CULTURE WITH IMPROVED STORAGE COMPOUND PRODUCTION CAPACITY
    Publication number: 20140242641
    Abstract: The invention is directed to a method for producing an open phototrophic culture with improved storage compound production capability. In accordance with the invention, a starting culture is submitted to selective pressure, thus giving a competitive advantage to storage compound producing species, by subjecting said starting culture to a cycle of alternating dark phases and light phases and providing limitation of availability of essential growth nutrients in one or more of said light phases. The resulting culture can be used to provide storage compounds in improved yields.
    Type: Application
    Filed: July 18, 2012
    Publication date: August 28, 2014
    Applicant: Technische Universiteit Delft
    Inventors: Jelmer Tamis, Robert Kleerebezem, Mark Cornelis Maria van Loosdrecht
  • Hybrid organic-inorganic system for producing biofuels
    Publication number: 20140242649
    Abstract: The present invention provides for a system for converting CO2 and H2 to one or more biologically derived compounds. In some embodiments, the system comprises a host cell comprising one or more nucleic acids encoding genes for a recombinant surface display protein which is capable of tethering an electrocatalyst molecule, such as a cobalt(II) complex supported by tetradentate polypyridyl ligand 2-bis(2-pyridyl)(methoxy)methyl-6-pyridylpyridine (PY4), and enzymes for synthesizing a biologically derived compound, such as an alkane, alcohol, fatty acid, ester, or isoprenoid.
    Type: Application
    Filed: May 8, 2014
    Publication date: August 28, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Yi-Chun Yeh, Steven W. Singer, Swapnil R. Chhabra, Harry R. Beller, Jana Mueller
  • Process for preparation of hexadecyl cis-9-tetradecenoate and hexadecyl cis-10-tetradecenoate
    Patent number: 8816109
    Abstract: Hexadecyl cis-9-tetradecenoate commonly known as Cetyl myristoleate (CMO) is being used for the treatment of osteoarthritis and other joint inflammatory diseases, cis-9-Tetradecenoic acid (cis-9-myristoleic acid) is the main precursor for the preparation of CMO. As there are limited natural plant sources for cis-9-tetradecenoic acid, the present invention aimed at the synthesis of cis-9-tetradecenoic acid methyl ester from oleic acid methyl ester. As oleic acid is not available in pure form, this has to be isolated from oleic acid-rich oils like olive oil. cis-10-Tetradecenoic acid methyl ester, an isomer of cis-9-tetradecenoic acid was also prepared from undecenoic acid methyl ester, a derivative of castor oil. Undecenoic acid is easily available commercially in pure form.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: August 26, 2014
    Assignee: Council of Scientific & Industrial Research
    Inventors: Lakshmi Anu Prabhavathi Devi Bethala, Nadpi Gangadhar Katkam, Vijayalakshmi Kunkuma, Ramakrishna Sistla, Madhusudhana Kuncha, Vamanrao Diwan Prakash, Badari Narayana Prasad Rachapudi
  • High eicosapentaenoic acid producing strains of
    Patent number: 8815566
    Abstract: Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an ?-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprise various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of EPA. Production host cells are claimed, as are methods for producing EPA within said host cells.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: August 26, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K Picataggio, Dana M. Walters Pollak, James John Ragghianti, Zhixiong Xue, Narendra S Yadav, Hongxiang Zhang, Quinn Qun Zhu
  • Ozonolysis of unsaturated fatty acids and derivatives thereof
    Patent number: 8815549
    Abstract: The invention relates to a method for the ozonolysis of unsaturated fatty acids and derivatives thereof, comprising a) ozonolysis of a fatty acid or of a derivative thereof in an organic phase comprising an organic solvent, and b) contacting the organic phase with an aqueous phase comprising catalase and preferably a buffer, where the fatty acid or the derivative thereof has a linear chain having at least eight carbon atoms, and the use of catalase for removing reactive oxygen species from a reaction mixture comprising ozonolysis products of an unsaturated fatty acid.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: August 26, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Matthias Ullrich, Peter Hannen, Martin Roos
  • VARIANT THIOESTERASES AND METHODS OF USE
    Publication number: 20140234920
    Abstract: The present invention relates to variant thioesterases and their use in plants, e.g., to increase enzymatic activity and to promote increased production of mid-chain length fatty acids (e.g., 8 to 14 carbons) and at desired ratios. Further disclosed herein are methods of manufacturing renewable chemicals through the manufacture of novel triglyceride oils followed by chemical modification of the oils. Oils containing fatty acid chain lengths of C8, C10, C12 or C14 are also disclosed and are useful as feedstocks in the methods described herein.
    Type: Application
    Filed: January 29, 2014
    Publication date: August 21, 2014
    Applicant: Solazyme, Inc.
    Inventor: David DAVIS
  • Enzymatic Preparation of Diols
    Publication number: 20140234917
    Abstract: The invention relates to enzymatic methods for hydroxylation in position 2 or 3 of two ends of a substituted or unsubstituted, linear or branched aliphatic hydrocarbons.
    Type: Application
    Filed: June 29, 2012
    Publication date: August 21, 2014
    Applicant: Novozymes A/S
    Inventors: Henrik Lund, Jesper Brask, Lisbeth Kalum, Ana Gutierrez Suarez, Esteban Daniel Babot, Rene Ullrich, Martin Hofrichter, Angel Tomas Martinez Ferrer, Jose Carlos Del Rio Andrade