Carbohydrate Or Lignin, Or Derivative Patents (Class 514/777)
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Patent number: 9044513Abstract: A crystallized maltitol powder including a maltitol content greater than 99.5% by weight, characterized by a particle-size distribution by volume, determined by laser granulometry, having less than 20% particles less than 200 ?m in size, less than 6% particles less than 100 ?m in size, less than 2% particles less than 40 ?m in size and a pour value less than or equal to 10 seconds, an aerated density greater than 0.85 g/ml, a compacted density greater than 0.97 g/ml, and a compressibility of less than 17%, and to its use in the pharmaceuticals and above all foods sectors, in particular in the formulation of chocolates or table sweeteners.Type: GrantFiled: February 20, 2009Date of Patent: June 2, 2015Assignee: ROQUETTE FRERESInventors: Manuel Barata, Yves Le Bot, Elsa Muller née Ostermann, Guillaume Ribadeau-Dumas
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Publication number: 20150148431Abstract: A composition suitable for use in a transdermal delivery patch for administration of a biologically active compound, the composition comprising a phosphate compound of tocopherol and a polymer carrier.Type: ApplicationFiled: November 21, 2014Publication date: May 28, 2015Inventors: Jeremy Cottrell, Giacinto Gaetano, Mahmoud El-Tamimy, Nicholas Kennedy, Paul David Gavin
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Publication number: 20150148355Abstract: A silicone gel (“silogel”) composition used to deliver pharmaceutical products transdermally as well as a method for producing the silogel composition, which may contain up to 80% additive ingredients. Preferred embodiments of the invention may include silogel compositions which provide high viscosity/no separation due to API. They are not temperature-sensitive, have no shear stress from the ointment mill/EMP, have no gumming up/stickiness, and no hardening.Type: ApplicationFiled: November 24, 2014Publication date: May 28, 2015Inventor: John Olin Trimble
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Publication number: 20150140133Abstract: A system is described for long-term controlled release delivery of a drug or a therapeutic agent. According to the invention, one or more drugs or therapeutic agents contained in microspheres are mixed with a temperature sensitive hydrogel which is then introduced directly to the desired situs of the drug or therapeutic agent. The temperature sensitive hydrogel may also contain a drug or a therapeutic agent, for example, a pain relieving drug, for a short-term controlled release. The temperature sensitive hydrogel is in liquid state at room temperature, but upon injection, shortly becomes gelatinous. This system is particularly suitable for treatment of diseases, disorders, or conditions, for example, tumors, discogenic back pain, or arthritis, warranting localized administration of a drug or a therapeutic agent. In addition, the specification provides a method for production of a drug- or therapeutic agent-containing microspheres.Type: ApplicationFiled: December 4, 2014Publication date: May 21, 2015Inventor: Tae-Hong Lim
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Publication number: 20150141524Abstract: The invention relates to a method for the production of a solid bio-product wherein at least 80% of the original indigestible oligosaccharide (raffmose, stachyose and verbascose) content has been degraded into digestible mono- and disaccharides, comprising the following steps: 1) providing a mixture of milled or flaked or otherwise disintegrated biomass, comprising oligosaccharides and optionally polysaccharides and further comprising proteinaceous plant parts, water and one or more enzyme preparations containing ?-galactosidase(s); 2) reacting the mixture resulting from step (1) under continuous mixing and under conditions where the water content in the initial mixture does not exceed 65% by weight, for 0.15-36 hours at a temperature of about 20-65° C.; 3) incubating the reacted mixture from step (2) at a temperature and in a time period which inactivate said ?-galactosidase(s), as well as solid bio-products obtainable by such method.Type: ApplicationFiled: May 5, 2013Publication date: May 21, 2015Applicant: Hamlet Protein A/SInventors: Katrine Hvid Ellegard, Karl Kristian Thomsen, Ole Kaae Hansen
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Patent number: 9029426Abstract: The invention relates to a process for producing highly soluble compositions containing purified steviol glycosides from Stevia rebaudiana Bertoni plant extract, more particularly Rebaudioside D. Obtained highly soluble compositions are useful as non-caloric sweeteners or in combination with sugar or high intensity sweeteners in edible and chewable compositions such as beverages, confectionaries, bakery products, chewing gums and the like.Type: GrantFiled: December 12, 2011Date of Patent: May 12, 2015Assignee: PureCircle Sdn BhdInventors: Avetik Markosyan, Siddhartha Purkayastha
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Publication number: 20150126616Abstract: N-methyl-N-acylglucamines are suitable as thickening agents in aqueous surfactant solutions containing one or more anionic surfactants of the group including alkyl ether sulfates and alkyl sulfates, the N-methyl-N-acylglucamines containing at least 60 wt.-% of N-methyl-N-acylglucamines that have a C12-, C14-acyl group or an unsaturated C18-acyl group and at the same time less than 5 wt.-% of N-methyl-N-acylglucamines that contain an acyl group <C12. The surfactant solutions are particularly used in cosmetic compositions.Type: ApplicationFiled: May 29, 2013Publication date: May 7, 2015Applicant: Clariant Finance (BVI) LimitedInventors: Peter Klug, Carina Mildner
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Publication number: 20150126618Abstract: A biologic formulation of 20% to 95% by weight of hyaluronic acid is provided such that the hyaluronic acid is the most common ingredient in the formulation. The formulation preferably also includes 0.1% to 1.5% by weight of a preservative, and a pH adjuster configured to provide a pH of less than 5.0 in the formulation. The hyaluronic acid is a combination of two or more different molecular weights of hyaluronic acid. The different molecular weights of hyaluronic acid are preferably cross-linked with glucosamine and ceramides.Type: ApplicationFiled: November 6, 2014Publication date: May 7, 2015Inventor: David E. Pollock
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Publication number: 20150126617Abstract: The present invention relates to a agave syrup product having a low water content. The agave syrup product retains the physical and palatable properties of untreated agave syrup while having a prolonged shelf-life. It can be advantageously used to sweeten beverages (such as hot beverages) and in the manufacture of pharmaceutical compositions (such as throat lozenges) and/or confectionary.Type: ApplicationFiled: July 11, 2013Publication date: May 7, 2015Inventor: John Lawrence Rowe
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Publication number: 20150125415Abstract: The invention relates to a composition which contains at least one anionic surfactant, a betaine surfactant, a mixture of N-methyl-N-acylglucamines, the acyl groups of which correspond to those of natural coconut oil and/or palm kernel oil, a glycerol derivative, a solvent and optionally one or more additives. The invention also relates to a method for producing the composition. The invention further relates to the use of the composition for the treatment or care of skin or hair, for example as a shampoo, face cleaner, liquid cleaner or shower gel.Type: ApplicationFiled: May 29, 2013Publication date: May 7, 2015Applicant: Clariant Finance (BVI) LimitedInventors: Peter Klug, Carina Mildner
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Patent number: 9023381Abstract: Pharmacologically effective amounts of a medication are delivered in pleasant tasting delivery vehicles, including gelatins and candies. Mechanisms for the reduction in surface area of noxious taste-imparting aspects of conventional medicines, and dilutive effects of positive masking elements for such medicines, especially products for inducing children to take medicines, are taught—in combination with processes and products thereby.Type: GrantFiled: October 31, 2007Date of Patent: May 5, 2015Inventor: Michelle Chow
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Publication number: 20150118322Abstract: The disclosure provides a biomedical composition, including: a hyaluronic acid; a modified histidine; and a polymer or C4-C20 alkane, wherein the modified histidine and the polymer or C4-C20 alkane are grafted to at least one primary hydroxyl group of the hyaluronic acid to allow the hyaluronic acid to form a hyaluronic acid derivative, wherein a graft ratio of the modified histidine is about 1-100%, and a graft ratio of the polymer or C4-C20 alkane is about 0-40%.Type: ApplicationFiled: October 14, 2014Publication date: April 30, 2015Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ya-Chin LO, Hsiang-Fa LIANG, Ming-Cheng WEI, Maggie J.M. LU, Min-Ying LIN, Chih-Peng LIU, Chun-MIN LIU, Hsiang-Wen TSENG, Tse-Min TENG, Jui-Hsiang CHEN, Yi-Man CHOU, Yi-Ting HSIEH, Chia-Mu TU
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Publication number: 20150118195Abstract: The presently disclosed subject matter provides a scalable and electrostretching approach for generating microfibers exhibiting uniaxial alignment from polymer solutions. Such microfibers can be generated from a variety of natural polymers or synthetic polymers. The hydrogel microfibers can be used for controlled release of bioactive agents. The internal uniaxial alignment exhibited by the presently disclosed fibers provides improved mechanical properties to microfibers, contact guidance cues and induces alignment for cells seeded on or within the microfibers.Type: ApplicationFiled: April 30, 2013Publication date: April 30, 2015Applicant: THE JOHNS HOPKINS UNIVERSITYInventors: Hai-Quan Mao, Shuming Zhang, Xi Liu, Brian Patrick Ginn
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Patent number: 9018236Abstract: Described herein are cyclodextrin-stabilized microemulsion systems useful for increasing the solubility, stability, bioavailability, or safety of an active agent for delivery to the skin. The microemulsions may reduce the occurrence of skin irritation or odor upon application.Type: GrantFiled: March 14, 2013Date of Patent: April 28, 2015Assignee: Precision Dermatology, Inc.Inventors: Mark W. Trumbore, Pinaki Ranjan Majhi, Dinen Divyang Shah
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Publication number: 20150111812Abstract: Hydrogels and hybrid hydrogels, methods of making the hydrogels/hybrid hydrogels, and methods of using the hydrogels/hybrid hydrogels. The hydrogels have polysaccharide moieties (e.g., chitosan or hyaluronic acid moieties). The hybrid hydrogels have polysaccharide moieties (e.g., chitosan or hyaluronic acid moieties) and poly(ester amide) moieties. The poly(ester amide) moieties can have one or more arginine moieties. The hydrogels/hybrid hydrogels can be used, for example, in consumer products and as cargo carrier materials (e.g., as therapeutic agent carriers).Type: ApplicationFiled: May 31, 2013Publication date: April 23, 2015Inventors: Chih-Chang Chu, DeQun Wu, Mingyu He
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Publication number: 20150111834Abstract: The disclosure provides a recipe for in-situ gel, formed by dissolving at least one polymer and at least one gel prevention agent in a polar solvent to form a solution and placing the solution in a condition for in-situ forming gels. The disclosure also provides an implant and a drug delivery system formed by the recipe.Type: ApplicationFiled: September 17, 2014Publication date: April 23, 2015Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Felice CHENG, Maggie J.M. LU, Yi-Ju KO, Min-Ying LIN, Shuen-Hsiang CHOU
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Publication number: 20150110875Abstract: Bolaamphiphilic compounds are provided according to formula I: HG2-L1-HG1??I where HG1, HG2 and L1 are as defined herein. Provided bolaamphilphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain.Type: ApplicationFiled: July 10, 2014Publication date: April 23, 2015Inventors: Charles LINDER, Sarina GRINBERG, Eliahu HELDMAN
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Patent number: 9012517Abstract: Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and optionally including proteins. In one aspect, hyaluronic acid-based compositions described herein include zero-length cross-linked moieties and optionally at least one active agent. The present hyaluronic acid-based compositions have enhanced flow characteristics, hardness, and persistence compared to known hyaluronic acid-based compositions. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.Type: GrantFiled: March 19, 2014Date of Patent: April 21, 2015Assignee: Allergan, Inc.Inventors: Karina Heredia Guillen, Ahmet Tezel
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Patent number: 9012520Abstract: Disclosed herein are sweetener compositions comprising at least one sweetener and at least one sweetness enhancer chosen from terpenes (such as sesquiterpenes, diterpenes, and triterpenes), flavonoids, amino acids, proteins, polyols, other known natural sweeteners (such as cinnamaldehydes, selligueians, hematoxylins), secodammarane glycosides, and analogs thereof, wherein the at least one sweetness enhancer is present in the composition in an amount at or below the sweetness detection threshold level of the sweetness enhancer, and the at least one sweetener and the at least one sweetness enhancer are different.Type: GrantFiled: December 28, 2010Date of Patent: April 21, 2015Assignee: The Coca-Cola CompanyInventors: Indra Prakash, Grant E. DuBois, Josef Klucik, Rafael Ignacio San Miguel, Rudolf Johann Fritsch, Venkata Sai Prakash Chaturvedula
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Publication number: 20150105478Abstract: The invention relates to a composition comprising a polyelectrolyte complex of a polyanion and a polycation, and comprising at least one biocide. A preferred composition comprises lignosulfonate and chitosan, preferably in relative a amount of from 1:2 to 60:1 (w/w). The invention further relates to methods for generating a composition according to the invention, and to uses of a mixture according to the invention for protecting an agricultural plant or plant part against a pathogen.Type: ApplicationFiled: March 5, 2013Publication date: April 16, 2015Inventors: Wilhelmus Maria van der Krieken, Wilhelmus Bernardus Albertus Hendrikus Rutten, Christiaan Gerardus Johannes Maria Jans
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Publication number: 20150104516Abstract: Cohesive high-dosage strength micronized active ingredients may be dispersed in dry powder formulations for inhalation comprising carrier particles, by use of the apparatus described herein.Type: ApplicationFiled: September 11, 2014Publication date: April 16, 2015Applicant: CHIESI FARMACEUTICI S.p.A.Inventors: Claudio CAFIERO, Federico TOSINI
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Publication number: 20150099928Abstract: In one aspect, the invention provides injectable compositions that comprise a suitable hydrophilic polymer (e.g., a suitable polysaccharide) and water, as well as other optional components. In various embodiments, the composition may be provided in a suitable container, for example, in a pre-loaded syringe. In another aspect, methods of performing medical procedures in a tract of a body are provided. In yet another aspect, the invention provides systems for performing medical procedures in a tract of a body.Type: ApplicationFiled: October 7, 2014Publication date: April 9, 2015Applicant: Boston Scientific Scimed, Inc.Inventors: Paul Smith, Felipe Torres, Samuel Raybin, Mary Jo Timm
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Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer
Patent number: 9000054Abstract: The present invention includes methods of stabilizing one or more sweet enhancers when they are exposed to a light source as well as liquid compositions containing one or more sweet enhancers and one or more photostabilizers.Type: GrantFiled: August 12, 2011Date of Patent: April 7, 2015Assignee: Senomyx, Inc.Inventors: Catherine Tachdjian, Donald S. Karanewsky, Xiao Qing Tang, Hanghui Liu -
Patent number: 8999305Abstract: The invention relates to a composition comprising (1) at least one polar modified polymer, (2) at least one compound selected from a hyperbranched polyol having at least two hydroxyl groups, a sugar silicone surfactant, and a gelling agent.Type: GrantFiled: June 29, 2010Date of Patent: April 7, 2015Assignee: L'OrealInventors: Hy Si Bui, Mohamed Kanji, Anita Chon Tong, Chunhua Li, Susan Halpern, Bruno Thierry Bavouzet
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Publication number: 20150093440Abstract: A method of making aggregate particles suitable for a powder aerosol composition that includes forming a dispersion of nanoparticulate drug and/or excipient in a non-aqueous liquid, and spray-drying the dispersion to generate aggregate particles having a mass median aerodynamic diameter of less than or equal to about 100 microns, and particles generated by such method, and compositions of said particles.Type: ApplicationFiled: October 13, 2011Publication date: April 2, 2015Applicant: GLAXO GROUP LIMITEDInventors: Michiel M. Van Oort, John N. Hong
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Publication number: 20150087656Abstract: Prolongation compositions for prolonging the presence of drugs in blood.Type: ApplicationFiled: November 26, 2014Publication date: March 26, 2015Inventors: Aida Salatinjants, Robert Salatinjants
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Publication number: 20150086631Abstract: Chitosan nanoparticles are provided for use in the in vivo treatment of connective tissues in root canal therapies. The nanoparticles are optionally linked with one or more photoactivatable compounds for providing antibactenal/antibiofilm properties, neutralizing bacterial byproducts and/or chemical/photodynamic crosslinking to achieve enhanced mechanical properties, chemical stability in connective tissues and/or to improve surface/interfacial integrity between filling material and connective tissue.Type: ApplicationFiled: March 21, 2013Publication date: March 26, 2015Applicant: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Anil Kishen, Annie Shrestha
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Publication number: 20150087725Abstract: A material is described herein. The material includes a multi-vinylsulfone containing molecule and a multi-nucleophile containing molecule. The material can form a hydrogel from an aqueous solution with dissolved multi-vinylsulfone and a multi-nucleophile. The aqueous solution can undergo gelation with a controllable gelation time to form the hydrogel upon administration to a space in a body. The hydrogel can form in situ with controllable properties, which allow the hydrogel to be used in many biomedical applications. Examples of biomedical applications include, but are not limited to, a volume/filler expander, a storage and delivery mechanism for biologics, and as a tissue interacting surface.Type: ApplicationFiled: November 29, 2012Publication date: March 26, 2015Inventors: Ying Chau, Yu Yu
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Patent number: 8986728Abstract: The present invention provides an implantable device having a biosoluble coating or a biosoluble body structure comprising a polyelectrolyte and a counterion and the methods of making and using the same.Type: GrantFiled: July 9, 2012Date of Patent: March 24, 2015Assignee: Abbott Cardiovascular Systems Inc.Inventors: Syed F. A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
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Publication number: 20150080220Abstract: Compositions including a highly branched alpha-D-glucan or modified forms thereof and a solute compound are described herein. The compositions can provide increased water solubility and/or increased rate of dissolution for the solute compound. The compositions can also provide increased stability for the solute compound. Methods for preparing and using compositions including a solute compound and a highly branched alpha-D-glucan are also described.Type: ApplicationFiled: April 19, 2013Publication date: March 19, 2015Inventors: Yuan Yao, Jingmin Zhang
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Patent number: 8981081Abstract: Methods of preparing highly purified steviol glycosides, particularly Rebaudioside D, are described. The methods include purification from the extraction stage of the Stevia rebaudiana Bertoni plant, purification of steviol glycoside mixtures, Rebaudioside D and Rebaudioside A from a commercial Stevia extract, and purification of Rebaudioside D from remaining solutions obtained after isolation and purification of Rebaudioside A and a high purity mixture of steviol glycosides. The methods are useful for producing high purity Rebaudioside D, Rebaudioside A, and steviol glycoside mixtures. The high purity steviol glycosides are useful as non-caloric sweeteners in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.Type: GrantFiled: March 11, 2011Date of Patent: March 17, 2015Assignee: PureCircle USA Inc.Inventor: Avetik Markosyan
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Patent number: 8980238Abstract: Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties. Furthermore, polymers exhibiting disulfide partial structures with mercaptonicotinamides or mercaptopyridoxins do not need to be protected against oxidation. In addition, they show comparatively higher permeation enhancing properties.Type: GrantFiled: September 29, 2010Date of Patent: March 17, 2015Assignees: Thiomatrix Forschungs—Und Beratungs GmbH, Croma Pharma GmbHInventor: Johannes Leierer
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Patent number: 8980230Abstract: The present invention is directed towards a process for making oral compositions comprising gel networks. The gel networks are formed from a fatty amphiphile dispersion and swelling surfactant. The fatty amphiphile dispersion comprises one or more fatty amphiphiles, one or more dispersing surfactants, and one or more solvents. A gel network is formed when the fatty amphiphile dispersion is combined with the swelling surfactant. A method of preparing the fatty amphiphile dispersion and oral composition is included.Type: GrantFiled: March 14, 2013Date of Patent: March 17, 2015Assignee: The Procter & Gamble CompanyInventors: Michael Jude LeBlanc, George Endel Deckner
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Publication number: 20150064117Abstract: Embodiments of this invention encompass a method for producing and purifying rebaudioside C. In particular, this invention relates to a method for purifying rebaudioside C compositions to obtain a substantially pure rebaudioside C product using one or more crystallization steps. Resulting polymorphic forms of rebaudioside C, substantially pure rebaudioside C compositions and their uses are disclosed.Type: ApplicationFiled: October 31, 2014Publication date: March 5, 2015Applicant: Redpoint Bio CorporationInventors: F. Raymond Salemme, Robert A. Daines
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Patent number: 8968769Abstract: The present invention features an orally disintegrating dosage form including from about 5% to about 40%, by weight, of at least one hydrated salt and a pharmaceutically active agent, wherein the at least one hydrated salt has a dehydration temperature of from about 20 to about 120 ° C.Type: GrantFiled: September 24, 2009Date of Patent: March 3, 2015Assignee: McNeil-PPC, Inc.Inventors: Frank Bunick, Joseph Luber
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Publication number: 20150057371Abstract: The present invention provides methods of on-demand, reversible generation of aqueous two-phase microdroplets core-shell microbeads, microparticle preparations comprising the core-shell microbeads, and drug delivery formulation comprising the microparticle preparations. Because these aqueous microdroplets have volumes comparable to those of cells, they provide an approach to mimicking the dynamic microcompartmentation of biomaterial that naturally occurs within the cytoplasm of cells. Hence, the present methods generate femtoliter aqueous two-phase droplets within a microfluidic oil channel using gated pressure pulses to generate individual, stationary two-phase microdroplets with a well-defined time zero for carrying out controlled and sequential phase transformations over time. Reversible phase transitions between single-phase, two-phase, and core-shell microbead states are obtained via evaporation-induced dehydration and water rehydration.Type: ApplicationFiled: August 20, 2013Publication date: February 26, 2015Inventors: Charles Patrick Collier, Scott Thomas Retterer, Jonathan Barton Boreyko, Prachya Mruetusathorn
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Publication number: 20150057372Abstract: An emulsion having stabilized perfluorocarbon(s) that includes an aqueous solution, an oil solution and a third phase which includes at least one perfluorocarbon and methods of making the stable perfluorocarbon containing emulsions. The aqueous and oil phases are first mixed together to form the emulsion. At least one perfluorocarbon is then added to the emulsion. Either the aqueous based solution or oil based solution may include at least one thickener. Moreover, the perfluorocarbon containing emulsion remains stable for a period of at least two weeks.Type: ApplicationFiled: August 23, 2013Publication date: February 26, 2015Applicant: Indermica, Inc.Inventor: Jennifer Clara Ellis
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Patent number: 8962698Abstract: A composition includes Mogroside V and a Rebaudioside component in a weight ratio ?1:1 and ?6:1, wherein the Rebaudioside component consists of one or more compounds selected from the group consisting of Rebaudioside A, Rebaudioside B and Rebaudioside D. A method of purifying a Luo Han Guo extract includes contacting the Luo Han Guo extract with activated carbon and a macroporous polymeric adsorbent resin, an ion exchange resin, or both. A composition includes a Luo Han Guo extract, wherein Mogroside V constitutes from 50 wt % to 75 wt % of the Luo Han Guo extract and the composition includes from 0 to 13 wt % in total relative to the Mogroside V of aromatic glycosides, and from 0 to 15 ppm of semi-volatile organic compounds relative to the Mogroside V.Type: GrantFiled: January 23, 2012Date of Patent: February 24, 2015Assignee: Tate & Lyle Ingredients Americas LLCInventors: John R. Bridges, Alfred Carlson, Brian Timothy Pohrte, Mary Quinlan, Timothy C. Schunk, Elber F. Tejada, Shelly Yuqing Zhou
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Patent number: 8962036Abstract: Disintegrable preparations of lanthanum carbonate prepared by co-precipitation, facilitating the manufacture of oral pharmaceutical dosage forms such as tablets, capsules, powders, granules, and sprinkles, and the use of such dosage forms to treat subjects with hyperphosphatemia are disclosed.Type: GrantFiled: January 21, 2010Date of Patent: February 24, 2015Assignee: Mylan Pharmaceuticals Inc.Inventors: Andrea Blum Works, John Twist, Okey Noe
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Patent number: 8961676Abstract: A non-toxic, biodegradable, and water soluble adhesive made from a reduction of all natural substances. The adhesive is suited for gluing ornamental accessories to infants, children, young adults, adults or pets. The adhesive is further suited for temporarily attaching items to surfaces. The adhesive may comprise a reduction of a mixture comprising a syrup, a nectar, and a refined sugar.Type: GrantFiled: August 5, 2013Date of Patent: February 24, 2015Assignee: Girlie Glue, L.L.C.Inventor: Katie Clark Hydrick
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Patent number: 8962697Abstract: The invention features biodegradable polymers for the delivery of biologically active agents. The polymers include at least one biologically active agent covalently attached via a polyamide linker susceptible to selective hydrolysis by peptidase enzymes. Hydrolysis of the polyamide linker releases the biologically active agent in vivo.Type: GrantFiled: June 29, 2007Date of Patent: February 24, 2015Assignee: Interface Biologics Inc.Inventors: Frank Laronde, Hanje Chen
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Publication number: 20150050334Abstract: The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer.Type: ApplicationFiled: August 27, 2014Publication date: February 19, 2015Inventors: Dominique Nicolas Cade, Xiongwei David He
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Publication number: 20150050320Abstract: A composition for diet supplementation to improve gut microflora is disclosed. The composition includes a prebiotic source and source of nucleotides, such as an extract of yeast. Also disclosed are methods of diet supplementation that include administering compositions of the invention to an individual.Type: ApplicationFiled: August 15, 2014Publication date: February 19, 2015Inventor: Mark G. CONNELL
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Publication number: 20150045311Abstract: The present invention related to low-chloride alkylated cyclodextrin compositions, along with processes for preparing and using the same. The processes of the present invention provide alkylated cyclodextrins with low levels of drug-degrading agents and chloride.Type: ApplicationFiled: February 27, 2013Publication date: February 12, 2015Inventor: Vincent D. Antle
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Publication number: 20150044136Abstract: The invention described herein relates to the composition of a liquid in which a silver ion moiety can act as a preservative as well as an astringent for the inhibition of microbial infections of the eye.Type: ApplicationFiled: August 12, 2013Publication date: February 12, 2015Inventors: George H. Scherr, Seth I. Kaplan
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Publication number: 20150045453Abstract: The purpose of the present invention is to provide an emulsified food product composition having good fluidity and emulsification stability, even when subjected to heat sterilization treatment, with which gastro-esophageal reflux can be prevented by gelling upon entering the stomach. By adding a gelling agent for gelling in the acidic region, at least one emulsion stabilizer selected from the group consisting of gum arabic and gum ghatti, and a divalent metal salt to the emulsified food product composition comprising a lipid, it is possible to realize the property of gelling upon entering the stomach and obtain good fluidity and emulsification stability, even if a heat sterilization treatment is used.Type: ApplicationFiled: March 8, 2013Publication date: February 12, 2015Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Naoyuki Endo, Kazuya Mizukai
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Patent number: 8946153Abstract: The subject invention is directed to a pharmaceutical composition comprising an open matrix network carrying a pharmaceutically active ingredient, wherein the open matrix network comprises levan.Type: GrantFiled: March 28, 2011Date of Patent: February 3, 2015Assignee: Ferring B.V.Inventors: Shweta Gupta, Varinder Ahuja, Tejas Gunjikar, Kristin Wannerberger
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Publication number: 20150031646Abstract: A carrier enhancing absorption of medication includes a target medication, an emulsifier, a small-molecular hyaluronic acid (HA) component, an absorption enhancer and a cream base, wherein the carrier promotes infiltration of target medication from skin over affected area and enhance the absorption efficacy of human body by synergistic interaction.Type: ApplicationFiled: July 25, 2013Publication date: January 29, 2015Inventor: MING-CHEN LEE
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Publication number: 20150025157Abstract: There is provided a novel gelator containing a sugar derivative. A gelator including a compound of Formula (1) or Formula (2): wherein each of R1 and R3 is independently a linear or branched alkyl group having a carbon atom number of 1 to 20, a cyclic C3-20 alkyl group, or a linear or branched alkenyl group having a carbon atom number of 2 to 20, n is 0 or an integer of 1 to 4, R2 is a hydrogen atom, a linear or branched alkyl group having a carbon atom number of 1 to 10, or an aryl group optionally having a substituent, and R4 and R5 are each a hydroxy group.Type: ApplicationFiled: March 8, 2013Publication date: January 22, 2015Inventors: Fumiyasu Ono, Seiji Shinkai, Osamu Hirata
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Publication number: 20150025023Abstract: The invention provides a method for preparing sulphoalkyl ether-?-cyclodextrin. The method comprises first contacting cyclodextrin with a base to form activated cyclodextrin. The method then comprises separately contacting the activated cyclodextrin with an alkyl sultone to form sulphoalkyl ether-?-cyclodextrin. The activation reaction is carried in batch and the sulphoalkylation reaction is carried out under continuous flow conditions.Type: ApplicationFiled: July 16, 2014Publication date: January 22, 2015Inventors: Tammy Savage, Stephen Wicks, John Mitchell