Mineral Oil-water Type Patents (Class 514/939)
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Patent number: 5320833Abstract: Arylpolyenecarboxylic acids and their derivatives of the formula I ##STR1## where Ar is phenyl, biphenylyl or naphthyl, each of which can be substituted by one to three C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, hydroxyl or phenoxy groups, or amino groups which can be mono- or di-substituted by C.sub.1 -C.sub.4 -alkyl groups, or one methylenedioxy group, it being possible for the substituents to be identical or different,R.sup.1 is hydrogen, an alkali metal or ammonium cation, C.sub.1 -C.sub.20 -alkyl or C.sub.2 -C.sub.20 -alkenyl,R.sup.2 is C.sub.1 -C.sub.8 -alkyl,R.sup.3 to R.sup.7 are each hydrogen or C.sub.1 -C.sub.4 -alkyl, andn is 0 or 1are used as sunscreen agents in cosmetic preparations.Type: GrantFiled: September 23, 1991Date of Patent: June 14, 1994Assignee: BASF AktiengesellschaftInventors: Gabriele Deckers, Rainer Becker, Bernd Wenderoth, Norbert Goetz, Karin Sperling-Vietmeier
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Patent number: 5279819Abstract: An improved instant foaming aerosol shave cream is provided which includes, in percent by weight of the entire composition, (a) about 70--90% water, (b) about 10-20% of a soap component comprising about 8-12% of an alkanolamine C.sub.14 -C.sub.18 fatty acid soap and about 2-4% of a nonionic surfactant having an HLB of at least about 15, (c) about 1-5% of a propellant having a vapor pressure of about 30-60 Psig at 70.degree. F., (d) about 0.1-5% of one or more emollients, and (e) about 0.3-4% of a foam stabilizer component comprising about 0.1-3% of a fatty alcohol, about 0.1-3% of a fatty alkanolamide, and about 0.01-0.6% of a fatty acid diester of polyethylene glycol having a molecular weight of at least about 1000. The compositions are oil-in-water emulsions and exhibit advantages associated with delayed-foaming shaving gels but with the convenience of instant foams.Type: GrantFiled: September 21, 1992Date of Patent: January 18, 1994Assignee: The Gillette CompanyInventor: Marilyn J. Hayes
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Patent number: 5250289Abstract: A sunscreening composition which comprises a water-in-oil emulsion which comprises a) 0.5 to 30% by weight of titanium dioxide having a mean primary particle size of less than 100 nm, b) 5 to 20% by weight of an oil phase, c) 1 to 15% by weight of an emulsifier, and d) at least 40% by weight of an aqueous phase. The titanium dioxide may be coated with aluminium stearate. Further sunscreening agents may be included. The oil phase may be a hydrocarbon oil, a wax, a natural oil, a silicone oil or a mixture. Preferred emulsifiers are sesquioleates such as polyglyceryl-2-sesquioleate or sorbitan sesquioleate, polyethoxylated esters of derivatives of natural oils such as polyethoxylated esters of hydrogenated castor oil or silicone emulsifiers such as silicone polyols.Type: GrantFiled: January 11, 1990Date of Patent: October 5, 1993Assignee: The Boots Company PLCInventors: Stephen Boothroyd, Edward Galley, Arija M. Stammers
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Patent number: 5242907Abstract: Tropical and temperate crops, particularly rice, maize, cotton, soya and fruit, can be protected, particularly against insect pests of the orders Leoidoptera, Diptera, Coleoptera, Hemiptera, Orthoptera, Dictyoptera, Hymenoptera and Isoctera and acarine pests, by treatment with a pesticidal water-miscible formulation whose average particle size is at most 200 nm. Public health pests, including the house fly (Musca domestica), cockroach (Blatta sp. or Periplaneta sp.) and mosquito (Aedes aegyoti) as well as pests which infest or affect timber, particularly in buildings, can also be controlled with such formulations. The formulations include water, oil, a surfactant, and a cosurfactant, wherein either the oil is a pesticide or the formulation comprises a pesticide dissolved in the oil. The pesticide may be a pyrethroid such as cypermethrin or deltamethrin. The formulations can be molecular solutions, micellar solutions or microemulsions (water-in-oil or oil-in-water) and are generally clear.Type: GrantFiled: April 29, 1991Date of Patent: September 7, 1993Assignee: NC Development, Inc.Inventor: Howard B. Dawson
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Patent number: 5234689Abstract: A multi-purpose, clear, anhydrous, liquid perfume composition comprising effective amounts of each of (a) one or more skin protective agents, (b) one or more skin moisturizers or emollients, (c) one or more emulsifiers, and (d) one or more perfume oils is disclosed. This composition can be used directly on the skin as a perfume, e.g., in the form of a vehicle similar to a dry oil spray, can be added directly to bath water as a perfumed bath oil, or can be mixed with water, e.g., in a jar, bottle or in situ on wet skin, to produce an emulsion body lotion.Type: GrantFiled: January 21, 1992Date of Patent: August 10, 1993Assignee: La Parfumerie, Inc.Inventors: Jerome I. Lindauer, Marcia Edwards
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Patent number: 5217648Abstract: A process is provided wherein hemoglobin, a fragile material, is formulated into high hemoglobin content water-in-oil-in-water multiple emulsion while maintaining high yields and high oxygen exchange activity. A multiple emulsion of aqueous oxygen carrying material in oil in outer aqueous phase is suitable for provision of oxygen for oxygen transfer processes. A hemoglobin multiple emulsion in physiologically compatible oil in an outer aqueous saline solution is provided in sufficiently small droplet size to provide oxygen flow through blood vessels to desired body tissues or organs thereby providing a blood substitute.Type: GrantFiled: October 11, 1991Date of Patent: June 8, 1993Assignees: Illinois Institute of Technology, Northfield Laboratories, Inc.Inventors: Richard L. Beissinger, Darsh T. Wasan, Lakshman R. Sehgal, Arthur L. Rosen
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Patent number: 5210099Abstract: The invention provides an analgesic cream containing ibuprofen with superior skin penetration properties obtained in part by maintaining a pH of 4 to 7.2 such that the ibuprofen is suspended in substantially solid crystalline form.Type: GrantFiled: January 8, 1992Date of Patent: May 11, 1993Assignee: American Home Products CorporationInventors: Dhiraj S. Mody, Robert G. Blank, Gary R. Agisim, Gloria Y. Chen
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Patent number: 5183589Abstract: Stable diphase emulsions consisting of:a) perfluoropolyethers having perfluoroalkyl end groups;b) a conventional surfactant,dispersed inc) a continuous dispersing phase consisting of glycerol or of a polyhydroxylated compound containing at least three hydroxyl groups, selected from polyalcohols and saccharides, dissolved in a hydrophile solvent and/or water.Type: GrantFiled: March 30, 1990Date of Patent: February 2, 1993Assignee: Ausimont S.r.l.Inventors: Fabio Brunetta, Giovanni Pantini
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Patent number: 5178871Abstract: A preferred method of producing an aqueous, stable double emulsion is disclosed. The first step of the method is the production of an "inner" emulsion. The inner emulsion is produced by combining water, a liquid hydrocarbon solvent, and an emulsifier, in an agitated mixing vessel, along with an effective amount of finely-divided particulate material, to produce an oil-in-water emulsion having a viscosity of no more than about 200,000 centipoises, wherein the finely-divided particulate material is substantially homogeneously-dispersed throughout the thus-produced oil-in-water emulsion. The second step of the method is the production of an "outer" emulsion. The outer emulsion is produced by combining a liquid hydrocarbon solvent, water, and an emulsifier, in an agitated mixing vessel, to produce a water-in-oil emulsion. The third step of the method is the production of a "dual" emulsion.Type: GrantFiled: June 26, 1991Date of Patent: January 12, 1993Assignee: S. C. Johnson & Son, Inc.Inventor: Francis L. Thill
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Patent number: 5160739Abstract: A cosmetic oil and water emulsion is described whose essential components are a polyalphaolefin and a coupling-solubilizing agent of the formula:HO--CH.sub.2 CHRO).sub.m (CH.sub.2).sub.n (OCHRCH.sub.2).sub.m' OHwherein m and m' are integers greater than 1, n is an integer greater than 3; and R is selected from the group consisting of hydrogen, C.sub.1 -C.sub.12 alkyl and mixtures thereof.Type: GrantFiled: September 12, 1991Date of Patent: November 3, 1992Assignee: Chesebrough-Pond's USA Co., Division of Conopco, Inc.Inventor: Vispi Kanga
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Patent number: 5147644Abstract: Mixtures of polyglycerol fatty esters obtainable by partial esterification of a polyglycerol mixture consisting offrom 0 to 5% by weight of monoglycerol,from 15 to 40% by weight of diglycerol,from 30 to 55% by weight of triglycerol,from 10 to 25% by weight of tetraglycerol,from 0 to 15% by weight of pentaglycerol,from 0 to 10% by weight of hexaglycerol andfrom 0 to 5% by weight of higher polyglycerolswith one or more saturated fatty acids of 12 to 22 carbon atoms or one or more unsaturated fatty acids of 16 to 22 carbon atoms, where the unsaturated fatty acid or fatty acid mixture used may furthermore contain up to 10% by weight of saturated fatty acids of 16 to 22 carbon atoms and the degree of esterification of the saturated or unsaturated fatty acids in the mixture is from 20 to 70%, are used as emulsifiers in cosmetic and pharmaceutical formulations.Type: GrantFiled: February 22, 1991Date of Patent: September 15, 1992Assignee: BASF AktiengesellschaftInventors: Knut Oppenlaender, Brigette Wegner, Karl Stork, Franz Frosch, Hans-Ulrich Wekel
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Patent number: 5109026Abstract: An immunoadjuvant capable of producing secondary antibody responses as great as 50 to 60% of those obtained using Freund's complete adjuvant (FCA) which responses decline at a slow rate while not showing the disadvantages associated with FCA. The immunoadjuvant comprises an immunoadjuvant oil such as a mineral oil, squalene or squalane and a polycationic polyelectrolyte immunoadjuvant such as DEAE-Dextran or polyethyleneimine. The immunoadjuvant preferably comprises an emulsion having the oil in one phase and an aqueous solution of the polycationic polyelectrolyte in the other phases. Such immunoadjuvants are used with antigens, such as conjugates of hormones, e.g. luteinizing hormone releasing hormone, and an immunogenic protein.Type: GrantFiled: April 17, 1989Date of Patent: April 28, 1992Assignee: Commonwealth Scientific and Industrial Research OrganizationInventors: Ronald M. Hoskinson, Robin D. G. Rigby, Phillip E. Mattner
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Patent number: 5082591Abstract: A surface active agent formed by a polyoxethylenated and polyoxypropylenated di and/or tri (1-phenyl ethyl) phenol with 16 to 35 statistically distributed recurrent oxyalkylenated units. The ratio between the number of recurrent oxyethylenated units and the number of recurrent oxypropylenated units ranges from 75/25 to 90/10. The surface active agent is prepared by means of the reaction of a di and/or tri (1-phenyl ethyl) phenol and a mixture of monoethylene glycol and monopropylene glycol with a monoethylene giycol/monopropyleneglycol molar ratio ranging from 75/25 to 90/10. The surface active agent can be used for producing concentrated emulsifiable solutions of active materials, in particular phytosanitary materials.Type: GrantFiled: May 30, 1989Date of Patent: January 21, 1992Assignee: Rhone-Poulenc ChimieInventors: Antonio Marchetto, Anghelito Mascheroni, Georges Ruffo
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Patent number: 5080889Abstract: The following diacylglycerin is useful for a cosmetic oil and a cosmetic composition such as pack, cream and emulsion. ##STR1## (where one each of R.sub.1, R.sub.2, and R.sub.3 denotes a residue of a straight-chain saturated fatty acid having 11-17 carbon atoms, a residue of a branched-chain saturated fatty acid having 10-18 carbon atoms, and a hydrogen atom).Type: GrantFiled: March 16, 1990Date of Patent: January 14, 1992Assignee: Kao CorporationInventors: Masahiro Katada, Kenji Masui, Hisao Oomura, Yukitaka Tanaka, Mitsuo Kondo, Takashi Komori
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Patent number: 5061688Abstract: A multiple emulsion of aqueous oxygen carrying material in oil in outer aqueous phase is suitable for provision of oxygen for oxygen transfer processes. A hemoglobin multiple emulsion in physiologically compatible oil in an outer aqueous saline solution is provided in sufficiently small droplet size to provide oxygen flow through blood vessels to desired body tissues or organs thereby providing a blood substitute. A process is provided wherein hemoglobin, a fragile material, is formulated into high hemoglobin content water-in-oil-in-water multiple emulsions while maintaining high yields and high oxygen exchange activity.Type: GrantFiled: August 19, 1988Date of Patent: October 29, 1991Assignees: Illinois Institute of Technology, Northfield Laboratories, Inc.Inventors: Richard L. Beissinger, Darsh T. Wasan, Lahksman R. Sehgal, Arthur L. Rosen
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Patent number: 5037640Abstract: Compositions containing selected indoles and m-nitro alkoxybenzenes are useful for imparting a tan coloration to the skin while concurrently functioning as sun screening compositions.Type: GrantFiled: November 22, 1989Date of Patent: August 6, 1991Assignee: Clairol IncorporatedInventors: Thomas M. Schultz, George Serban, Alexander C. Chan
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Patent number: 5028418Abstract: Perspiration is decreased in an area of the skin subject to perspiration by applying to such area an antiperspirant amount of an imidazole derivative of the formula I ##STR1## wherein X is O or S and Y is Cl or H, or a dermatologically acceptable salt thereof, preferably in a dermatologically acceptable compatible vehicle.Type: GrantFiled: March 19, 1990Date of Patent: July 2, 1991Assignee: Bristol-Myers Squibb CompanyInventors: Michael D. Helman, Thomas A. Re
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Patent number: 5017605Abstract: A cosmetic preparation consists essentially of a mixture of a stable oil/water emulsion of cosmetically acceptable ingredients and a stable water/oil emulsion of cosmetically acceptable ingredients. The new preparation is prepared by mixing the two original emulsions such that a superfinely dispersed product is obtained. The particle size of the inner phases of the emulsions is 2-50 .mu.m. The preparation provides needed ingredients such as fats or moisture to skin of varying types. An example of the cosmetic preparation is a cream containing jojoba oil.Type: GrantFiled: August 3, 1989Date of Patent: May 21, 1991Assignee: Schering Wien Ges. m.b.H.Inventor: Wolfgang Stindl
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Patent number: 5004598Abstract: This invention relates to stable oil-in-water emulsions and to products based on such emulsions which contain a modified polymer which is a copolymer of a preponderant amount of an acrylic acid and a smaller amount of a long chain acrylate monomer which modified polymer renders the emulsions stable for over a year at room temperature and which imparts to the emulsions the quick breaking property whereby the emulsions break on coming in contact with an electrolyte or skin, instantaneously coalescing and releasing oil from the emulsions.Type: GrantFiled: May 31, 1989Date of Patent: April 2, 1991Assignee: The B. F. Goodrich CompanyInventors: Robert Y. Lochhead, Janet Y. Castaneda, Wilfred J. Hemker
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Patent number: 5002974Abstract: A long lasting, esthetically pleasing medicated skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65%;(3) an effective amount of a topical medicament; wherein the oil phase is added to the aqueous phase to form an emulsion and a topical medicament admixed into the emulsion has been developed.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: March 26, 1991Assignee: Warner-Lambert Co.Inventor: Navin M. Geria
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Patent number: 5000945Abstract: A process for stabilizing a specific UVB absorbing compound which comprises adding to said UVB absorbing compound at least one specific UVA absorbing compound in an amount of 0.1-10 parts by weight based on 1 part by weight of UVB absorbing compound is disclosed and also a cosmetic composition and a UV absorber, both containing said specific UVB absorbing compound and said specific UVA absorbing compound, respectively.Type: GrantFiled: September 8, 1988Date of Patent: March 19, 1991Assignee: Ajinomoto Co., Inc.Inventors: Toru Kobayashi, Takeshi Miyoshi, Masahiro Takehara
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Patent number: 5000946Abstract: The invention relates to sunscreen compositions comprising an effective component at least one compound of formula I ##STR1## wherein R.sup.1 is selected from alkyl, alkenyl, alkynyl substituted alkyl, substituted alkenyl, phenyl, substituted phenyl, substituted benzyl, cycloalkyl, cycloalkenyl, substituted cycloalkyl, substituted cycloalkenyl and polymeric groups;R.sup.2 is selected from hydrogen, alkyl and alkoxy; and wherein R.sup.1 and R.sup.2 may form a carbocyclic ring which may be substituted;R.sup.3 is selected from alkyl, sustituted alkyl, alkenyl, substituted alkenyl, alkynyl, phenyl, benzoyl, substituted phenyl, substituted benzyl, substituted benzoyl, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, alkanyoyl, substituted alkanoyl, polymeric groups, the group OROROR.sup.9 wherein R is a bivalent hydrocarbon radical and R.sup.9 is alkyl, alkenyl, phenyl benzyl, substituted phenyl, substituted benzyl;R.sup.4 is alkyl or alkoxy; n is an integer from 0 to 4; andR.sup.Type: GrantFiled: May 26, 1988Date of Patent: March 19, 1991Inventors: Graham Bird, Neil Fitzmaurice, Walter C. Dunlap, Bruce E. Chalker, Wickramasinghe M. Bandaranayake
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Patent number: 4994263Abstract: A composition for treatment and treatment of certain skin diseases is disclosed. The treatment combines furocoumarins, UV-A radiation, and a benzylidene-camphor derivative. The composition and treatment produces the desirable results of the furocoumarin/UV-A radiation treatment without the undesirable phototoxic side effects.Type: GrantFiled: April 30, 1990Date of Patent: February 19, 1991Assignee: L'OrealInventors: Gerard Lang, Andre Deflandre, Irena Beck
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Patent number: 4992478Abstract: A long lasting, esthetically pleasing medicated skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65%;(3) an effective amount of a topical medicament; wherein the medicament is a corticosteroid and the oil phase is added to the aqueous phase to form an emulsion and a topical medicament admixed into the emulsion has been developed.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria
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Patent number: 4992477Abstract: A long lasting, esthetically pleasing skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65% wherein the oil phase is added to the aqueous phase to form an emulsion has been developed. The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria
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Patent number: 4992476Abstract: A long lasting, esthetically pleasing skin cleansing and care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65% wherein the oil phase is added to the aqueous phase to form an emulsion has been developed,(3) an effective amount of an abrasive to remove oily deposits, cosmetics and particulates from the skin surface.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria
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Patent number: 4988501Abstract: Sunscreen compositions comprising at least one bis-1,3-diketone derivatives of benzene and a cosmetically acceptable carrier are described. Also disclosed is a method of protecting human skin from the harmful effects of ultraviolet radiation employing such sunscreen composition.Type: GrantFiled: March 19, 1990Date of Patent: January 29, 1991Assignee: ICI Americas Inc.Inventor: Donald J. Gosciniak
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Patent number: 4980084Abstract: A water rinsable petroleum jelly formulation, which is a water-in-oil preferably translucent emulsion, is described which comprises an aqueous phase containing a humectant, as a preferable component, and a surface active detergent effective to confer rinsable characteristics on the emulsion, an oil phase comprising a petroleum jelly component, and a water-in-oil emulsifying agent.Type: GrantFiled: October 5, 1988Date of Patent: December 25, 1990Assignee: Chesebrough-Pond's USA Co., division of CONOPCO, INC.Inventors: Mohan Vishnupad, Jose E. Ramirez, Thomas M. Deppert
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Patent number: 4960764Abstract: An oil-in-water-in-silicone fluid (o/w/s) emulsion composition comprising (a) a silicone fluid continuous phase, (b) an aqueous discontinuous phase comprising an oil-in-water (o/w) emulsion, and (c) an effective dispersing amount of dimethicone copolyol for dispersing (b) in (a).Type: GrantFiled: February 15, 1989Date of Patent: October 2, 1990Assignee: Richardson-Vicks Inc.Inventors: Ramon Figueroa, Jr., Bobby G. Harrison, Jr., James P. SaNogueira
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Patent number: 4954532Abstract: A degreasing or moisturizing composition contains silanized silica gel, a humectant such as glycerine, and an inert carrier. The composition is used to treat sebhorreic conditions without causing dry skin.Type: GrantFiled: January 30, 1985Date of Patent: September 4, 1990Assignee: Beecham Group p.l.c.Inventors: Thomas J. Elliott, Susan Dutton
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Patent number: 4950467Abstract: Sunscreen compositions are described which contain certain 5-phenylpentadienoate esters which act as UV filters when incorporated in a carrier in amounts ranging from 0.1-50% by weight.Type: GrantFiled: November 14, 1986Date of Patent: August 21, 1990Assignee: ICI Americas Inc.Inventors: Charalambos J. Phalangas, Alfred J. Restaino, Lau S. Yang
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Patent number: 4946671Abstract: Disclosed are pharmaceutical compositions comprising sorbohydroxamic acid, or pharmaceutically-acceptable salts thereof, and an anti-inflammatory agent, which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of sorbohydroxamic acid and an anti-inflammatory agent together with tocopherol sorbate and/or sunscreens are also disclosed.Also disclosed is a method for using these compositions topically to prevent damage to skin caused by acute or chronic UV exposure.Type: GrantFiled: May 2, 1989Date of Patent: August 7, 1990Assignee: The Procter & Gamble CompanyInventors: Donald L. Bissett, Ranjit Chatterjee
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Patent number: 4929439Abstract: Cosmetic screening composition in the form of an oil-in-water emulsion comprising a UV-A screening compound and a UV-B screening compound and its use for the protection of the skin against ultraviolet radiation.The invention relates to a cosmetic composition in the form of an oil-in-water emulsion which screens out UV rays of wavelengths of between 280 and 400 nm, which comprises partially or completely neutralized benzene-[1,4-bis(3-methylidenecamphomethylsulphonic acid)], in combination with N-(2-ethylhexyl)-4-(3-methylidenecamphor)benzenesulphonamide.The sun protection composition of this kind possesses a high index of protection, enabling it to be used on skins that are very sensitive or continually exposed to solar radiation.Type: GrantFiled: February 4, 1988Date of Patent: May 29, 1990Assignee: L'OrealInventors: Jean Cotteret, Jean F. Grollier
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Patent number: 4923698Abstract: A film-forming bioactive composition for control of crawling insects and the like is disclosed. Also disclosed are methods of producing and utilizing the bioactive composition. The bioactive composition comprises a water-in-oil emulsion, a bioactive ingredient dispersed throughout the emulsion, and a lubricating agent also dispersed throughout the emulsion. The water-in-oil emulsion comprises a continuous phase, an aqueous discontinuous phase, and an emulsifier system for dispersing the discontinuous phase throughout the continuous phase. The bioactive composition of the present invention is characterized in that after particles of the instant bioactive composition have been applied to a surface, a substantial portion of the continuous and discontinuous phases will evaporate over time, leaving a residual film on the surface. Such film comprises the emulsifier system, the bioactive ingredient, and the lubricating agent.Type: GrantFiled: January 6, 1989Date of Patent: May 8, 1990Assignee: S. C. Johnson & Son, Inc.Inventor: Alejandro Rodero
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Patent number: 4921874Abstract: There is described a medicinal bath oil containing about 68-95 percent by weight of one or more physiologically acceptable oil and about 30-5 percent by weight of one or more physiologically acceptable emulsifiers, at least one of which is a fatty alcohol polygolyol ether.Type: GrantFiled: August 17, 1987Date of Patent: May 1, 1990Assignee: Merck Patent Gesellschaft mit Beschrankter HaftungInventors: Rolf Franke, Peter Schmersahl
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Patent number: 4908147Abstract: A method for cleaning or preserving a soft contact lens comprising intimately contacting said soft contact lens with an aqueous solution containing an effective surfactant and solution preservative amount of an amphoteric surfactant of the formula: ##STR1## wherein R is alkyl, alkenyl or alkanedienyl of six to eighteen carbon atoms which may be substituted;A is --O--, --S--, ##STR2## where R' is hydrogen or lower alkyl; R.sub.1 is alkylene of 2 to 6 carbon atoms, which is unsubstituted or substituted by hydroxy;n is 0 or 1;R.sub.2 and R.sub.3 are independently hydrogen or lower alkyl which is unsubstituted or substituted by carboxy or one or two hydroxyls, one of which may be esterified with phosphoric or sulfuric acid; andR.sub.4 is alkylene of up to 3 carbon atoms, which is unsubstituted or substituted by hydroxy; and the ophthalmologically acceptable salts thereof; and compositions for use in such methods.Type: GrantFiled: March 16, 1989Date of Patent: March 13, 1990Assignee: Ciba-Geigy CorporationInventors: Fupao Tsao, Allen Penley
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Patent number: 4908154Abstract: Method and apparatus for forming emulsions, a term used to include microemulsions. The leading edges of a plurality of sheets of an emulsion-forming liquid mixture are forced under pressure to impinge in a low-pressure turbulent zone of the liquid. The apparatus comprises a plurality of nozzles having elongated orifices to eject under pressure sheets of the emulsion-forming liquid and being arranged to effect impingement of the sheets along a common liquid jet interaction front. Inasmuch as the method and apparatus permit the formulation of emulsions without the use of any emulsifiers, there is provided a new class of emulsions, namely those essentially free of any emulsifying agents. The emulsions formed have a wide range of applications.Type: GrantFiled: May 26, 1987Date of Patent: March 13, 1990Assignee: Biotechnology Development CorporationInventors: Edward J. Cook, Arthur P. Lagace
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Patent number: 4906457Abstract: Compositions and methods for reducing the risk of skin cancer. The novel compositions include at least one effective protease inhibitor. Preferred protease inhibitors include serine protease inhibitors and metallo- protease inhibitors. The protease inhibitors are preferably included in concentrations ranging from approximately 10 picograms to 10 milligrams per milliliter of the skin-applicable topical mixtures. The topical mixtures preferably include a suitable topical vehicle such as a cream, lotion, or ointment. One class of anti-carcinogenic skin treatment compositions of this invention preferably includes the desired protease inhibitors in combination with a suitable sunscreen agent or agents, such as para-amino benzoic acid, to provide particularly advantageous compositions for reducing the risk of sunlight-induced skin cancer.Type: GrantFiled: September 6, 1988Date of Patent: March 6, 1990Assignee: Washington State University Research Foundation, Inc.Inventor: Clarence A. Ryan
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Patent number: 4883652Abstract: Skin treating composition on the basis of compatible carrier and additional compositions with a content of a defined tetrahydro-1,3-thiazine-2,4-dion derivatives as active ingredients for thickening the epidermis. The skin treating compositions are applied 1-2 times daily onto the skin for about 3 to 4 weeks. Due to the thickening of the epidermis they cause a reinforcement of the skin, in particular against sun rays, cold and the contact with noxious environmental substances of all kinds. Moreover, the skin treating compositions are suitable for a prophylactic fighting of the so-called old age skin. An object of the invention are novel tetrahydro-1,3-thiazine-2,4-dion derivative which are active in the aforementioned manner having the formula ##STR1## wherein R denotes H, alkyl, aryl, arylalkyl has substituted arylalkyl or substituted aryl in the aryl portion, R.sup.2 =H is aryl or substituted aryl, R.sup.b =H, denotes aryl or substituted aryl and R.sup.3 =H, represents alkyl or aryl, provided that R.sup.Type: GrantFiled: March 2, 1988Date of Patent: November 28, 1989Assignee: Wella AktiengesellschaftInventors: Wolfgang Hanefeld, Rudi Rothlisberger, Friedrich Noser
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Patent number: 4869897Abstract: Disclosed are pharmaceutical compositions comprising sorbohydroxamic acid, or pharmaceutically-acceptable salts thereof, which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of sorbohydroxamic acid together with tocopherol sorbate and/or sunscreens are also disclosed.Also disclosed is a method for using these compositions topically, prior to UV exposure, to prevent damage to skin caused by acute or chronic UV exposure.Type: GrantFiled: October 22, 1987Date of Patent: September 26, 1989Assignee: The Procter & Gamble CompanyInventors: Ranjit Chatterjee, Stephen J. Kirchner
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Patent number: 4839160Abstract: An ultraviolet radiation absorbing polymer having units of formula I: ##STR1## wherein X is a group derived from benzylidene-bornanone of formula II ##STR2## wherein R.sup.1 represents hydrogen or C.sub.1 -C.sub.12 alkoxy andR.sup.2 represents C.sub.4 -C.sub.12 alkyl.The polymer is useful in protecting human skin against sunburn.Type: GrantFiled: March 25, 1987Date of Patent: June 13, 1989Assignee: L'OrealInventors: Serge Forestier, Claude Mahieu
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Patent number: 4832858Abstract: A stable, water dispersible petroleum jelly formulation, which is an oil-in-water emulsion, is described which comprises water, petroleum jelly, optional humectant, and emulsifier. The composition is formed by ultrasonically emulsifying the various components which will ultimately form the emulsion.Type: GrantFiled: February 19, 1987Date of Patent: May 23, 1989Assignee: Chesebrough-Pond's Inc.Inventors: Mohan Vishnupad, Jose E. Ramirez, Robert A. Bornfriend
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Patent number: 4822614Abstract: A film-forming bioactive composition for control of crawling insects and the like is disclosed. Also disclosed are methods of producing and utilizing the bioactive composition. The bioactive composition comprises a water-in-oil emulsion, a lubricating agent also dispersed throughout the emulsion. The water-in-oil emulsion comprises a continuous phase, an aqueous discontinuous phase, and an emulsifier system for dispersing the discontinuous phase throughout the continuous phase. The bioactive composition of the present invention is characterized in that after particles of the instant bioactive composition have been applied to a surface, a substantial portion of the continuous and discontinuous phases will evaporate over time, leaving a residual film on the surface. Such film comprises the emulsifier system, the bioactive ingredient, and the lubricating agent.Type: GrantFiled: December 19, 1986Date of Patent: April 18, 1989Assignee: S. C. Johnson & Son, Inc.Inventor: Alejandro Rodero
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Patent number: 4816247Abstract: Lipid emulsion form compositions have been formulated and presented to eliminate adverse injection site reactions associated with the intravenous administration of certain sparingly water soluble, hydrophobic, ionizable drugs in mammals and to provide a solubilized drug form for oral, parenteral or intraarticular administration which enhances drug absorption and the therapeutic efficacy of the drug.Type: GrantFiled: September 11, 1985Date of Patent: March 28, 1989Assignee: American Cyanamid CompanyInventors: Narendra R. Desai, Edward C. Shinal, Madurai Ganesan, Eugene A. Carpentier
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Patent number: 4806344Abstract: The invention relates to a composition and method of dissolving melanin in a composition for the purpose of photoprotection of the human epidermis from exposure to the sun's harmful rays. The composition consists of melanin, as an active ingredient, sunscreens, vitamins and emollients. These ingredients are rapid blended by ultrasound for 2-3 hours to form a mixture that enhances the sun protective factor when applied topically.Type: GrantFiled: January 5, 1987Date of Patent: February 21, 1989Inventor: Frances C. Gaskin
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Patent number: 4803067Abstract: Compositions for cosmetics and dermatology comprising a perfluoropolyether liquid dispersed in an oil/water or water/oil emulsion, or in a solid phase suited to form a gel, suspended in an organic liquid phase.Type: GrantFiled: March 26, 1986Date of Patent: February 7, 1989Assignee: Ausimont S.p.A.Inventors: Fabio Brunetta, Stefano Bader, Giovanni Pantini
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Patent number: 4801455Abstract: A pharmaceutical formulation for the parenteral, in particular intravenous, administration of sparingly soluble substances is obtained when the very finely ground substance, with a maximum particle diameter of 3 .mu.m, is dispersed in an oil phase which contains emulsifier, and this mixture is emulsified with water for injection, is rendered isotonic and is homogenized using a high-pressure homogenizer, so that the resultant product is a solid/liquid/liquid disperse system.Type: GrantFiled: July 9, 1987Date of Patent: January 31, 1989Assignee: Behringwerke AktiengesellschaftInventors: Paul H. List, Peter C. Schmidt, Klaus-Jurgen Steffens, Harald Perschbacher, Hans P. Kraemer, Hans H. Sedlacek
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Patent number: 4785013Abstract: Composition containing:a--from 20 to 40% of iprodione,b--an oil-in-water emulsion containing 50 to 160% by weight, relative to the iprodione, of an oil of which the hydrophilic/lipophilic balance has a value of 9 to 12, andc--from 0.1 to 2% by weight of an emulsifier of the ethylene oxide/fatty alcohol condensate type.Composition for the protection of plants against fungal diseases.Type: GrantFiled: June 6, 1984Date of Patent: November 15, 1988Assignee: Rhone-Poulenc AgrochimieInventor: Albert Margossian
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Patent number: 4784845Abstract: This disclosure describes quick breaking, in vivo, intravenous, intramuscular, intraarticular fat emulsion compositions which incorporate the use of benzyl alcohol as a consurfactant and/or a cosolvent in combination with materials such as synthetic surfactants, e.g. sorbitan triisostearate, triglycerol diisostearate or triglycerol pentaoleate; naturally occurring vegetable oils, e.g. sesame oil, and soybean oil; natural lecithins such as egg lecithin or soy lecithin; saturated or unsaturated aliphatic acids, e.g. oleic acid, hexanoic acid and linolenic acid; and other excipients such as glycerine, polyvinylpyrrolidone, Pluronic.RTM. F-68 and di-.alpha.-tocopherol.Type: GrantFiled: September 16, 1985Date of Patent: November 15, 1988Assignee: American Cyanamid CompanyInventors: Narendra R. Desai, Edward C. Shinal, Madurai Ganesan, Eugene A. Carpentier
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Patent number: RE33845Abstract: A skin tanning composition comprising (a) 5 to 50% by weight of an oil fraction of straight or branched paraffinic oils of 10 to 30 carbon atoms with a boiling range of 100.degree. to 500.degree. C. at atmospheric pressure and a viscosity of at most 35 centistokes at 25.degree. C., optionally containing up to 6% by weight of esters of optionally unsaturated higher natural fatty acids and optionally unsaturated natural aliphatic alcohols of up to 20 carbon atoms, (b) 1 to 10% by weight of an emulsifying system comprising (1) 1 to 10% by weight of mono and/or diglycerides of higher optionally unsaturated natural fatty acids and (2) ethoxylated glycerides esterified with fatty acids of the formula ##STR1## wherein n is an integer from 5 to 20 and the R's are individually an optionally unsaturated fatty acid residue derived from animal or vegetable oils with a ratio of 10 to 100 parts by weight of (1) per part by weight of (2), (c) .Iadd.(.Iaddend.1.0 to 5% by weight of a mixture.Iadd.) .Iaddend..Iadd.Type: GrantFiled: December 20, 1990Date of Patent: March 10, 1992Assignee: Chemisch Adviesbureau Drs. J.C.P. Schreuder B.V.Inventor: J. C. P. Schreuder