Abstract: The present invention relates to methods for making highly crystalline polymeric material, for example, highly crystalline cross-linked and not cross-linked ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making additive-doped highly crystalline polymeric material using high pressure and high temperature crystallization processes, medical implants made thereof, and materials used therein.

Abstract: The present invention relates to methods for making highly crystalline cross-linked polymeric material, for example, highly crystalline cross-linked ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped highly crystalline cross-linked polymeric material using high pressure and high temperature crystallization processes, medical implants made thereof, and materials used therein.

Abstract: An easily removable dental curable composition which prevents the fall or leakage of a temporary prosthetic appliance or a root canal filling material which is easily removed by bonding and adhering it to tooth, shows such high flowability that its operation is easy, has a long working time and excellent X-ray contrast properties and sealability and can be easily removed as required, and a filling kit. The dental curable composition comprises (A) a polymerizable monomer mixture containing a polymerizable monomer having an acid group in the molecule and (B) a polymerization initiator, wherein the component (A) contains (A?) a long-chain polymerizable monomer having a structure with a chain length of 17 or more atoms and/or the composition further comprises (D1) a soft resin material.

Abstract: There is provided a dental composite restorative material that has an excellent opalescent effect, no paste stickiness, small polymerization shrinkage during curing and is suitable for the restoration of the incisal edge of a tooth. This dental composite restorative material comprises: (A) a polymerizable monomer, (B) a spherical silica-based particle [I] having an average particle diameter in the range of from 0.1 to 0.5 ?m and a standard deviation of particle diameter distribution within 1.30, preferably a silica-titanium group oxide-composite oxide particle, (C) an organic-inorganic composite filler prepared by dispersing the above-described silica-based particle [I] in an organic resin matrix, and (D) a polymerization initiator.

Abstract: Methods for making dental crowns, bridges, inlays, onlays, veneers, fillings, and other restorations are provided. The methods involve using a two-phase light curing (TPLC) material. Preferably, the TPLC material used to form the dental restoration comprises a blend of polymerizable compounds; photopolymerization systems (a) and (b), and particulate filler materials (a) and (b). In a first light-curing step, curing light having a wavelength of greater than 420 nm is used to activate system (a). In a second light-curing step, curing light having a wavelength of less than 420 nm is used to activate system (b). The two step light-curing method is efficient and allows the dentist to make restorations having high mechanical strength and pleasing aesthetics.

Abstract: A method of preparing a ceramic-resin composite material for bone repair, including preparing a predetermined amount of pH controlled substantially anhydrous coupling agent by mixing a liquid silane material, alcohol and organic acid, producing particulate bioactive glass having a desired particle size of less than about 53 mesh, measuring a desired quantity of the particulate bioactive glass into a mixing vessel, heating the mixing vessel and particulate bioactive glass to about 100 degrees Celsius, mixing the heated quantity of particulate bioactive glass and spraying a predetermined amount of substantially anhydrous coupling agent into the heated quantity of particulate bioactive glass to define an admixture, mixing the admixture for sufficient time to define a quantity of substantially evenly coated particles, heating the quantity of substantially evenly coated particles for sufficient time to evolve excess solvent therefrom, and incorporating the quantity of substantially evenly coated particles into a r

Abstract: Compositions containing (A) at least one silane-terminated polyether derivative with a content of polyether groups from 10 to 98% and a content of 1 to 25% terminal groups with the structure —NR1—X—Si(OR2)mR3(3-m)??(I) in which m denotes 1, 2 or 3 R1, R2, R3 independently of each other denote H or a saturated or unsaturated, linear, branched, cyclic or polycyclic hydrocarbon group with 0 to 10 heteroatoms from the group O, N, S and a total of 1 to 30 carbon atoms, X denotes a group with the empirical formula CnH2n, n denotes a whole number ?3, with the stipulation that n>3, if R1 stands for H, (B1) water and (B2) at least one organic or inorganic acid, as well as optional diluents and/or fillers and/or ordinary additives, are suitable for preparation of molding compounds, especially in the dental field.

Abstract: Disclosed are phospholipid based compositions and implant devices, as well as methods and kits that include such compositions or components thereof. In particular, the present compositions include a polymer component such as a poloxamer or PEG component and a phospholipid component, such as a Phosal. The present compositions may include at least one additional component, such as granules, powder and/or particulates. The present compositions may further include one or more bone graft materials and/or active ingredients. The compositions may be used on their own or incorporated on or in a surgical implant.

Abstract: The invention provides methods for inducing reversible chain cleavage of polymer chains in a crosslinked polymeric material. Reversible cleavage of the polymer backbone is capable of relieving stress in the polymeric material as the bonds reform in a less stressed state. The invention also provides methods for making polymeric materials capable of reversible chain cleavage, materials made by the methods of the invention, and linear monomers containing reversible chain cleavage groups which are useful in the materials and methods of the invention.

Abstract: Polymerizable dental material which contains (a) at least one radically polymerizable compound according to the general formula I (b) initiators for radical polymerization; and (c) filler.

Abstract: Disclosed are photopolymerizable compositions suitable for uses such as dental composite resins, and that comprise (A) a radical-polymerizable monomer, (B) a photopolymerization initiator that comprises (B1) an ?-diketone compound, (B2) a photoacid generating agent, (B3) an aromatic amine compound, and (C) an organic filler containing a phthalate ester fluorescent agent.

Abstract: The present invention provides a dental polymerizable composition which has excellent handling property by the brush-dip technique and the bulk-mix technique, particularly excellent handling property by the brush-dip technique, contains few air bubbles, is excellent in color tone, polishability, mechanical properties and the discoloration resistance of a cured product at the time of curing and is used for many purposes such as the repair of a denture base or artificial tooth, a tooth crown prosthetic restoration and a temporary prosthetic restoration which is used until a bridge is completed when it is a two-composition type self-curing resin. The dental polymerizable composition comprises three different types of (meth)acrylate polymer particles, each having specific particle size characteristics and specific molecular weight characteristics.

Abstract: Dental compositions and biphenyl di(meth)acrylate monomers are described. The dental compositions comprise at least one biphenyl di(meth)acrylate monomer comprising two aromatic rings connected with a C—C bond wherein the rings each comprise a substituent comprising a urethane moiety and a (meth)acrylate end group.

Abstract: A method for making a composite material with non-spherical reinforcing particles embedded in a matrix, is disclosed. In this method, in a first step magnetic and/or superparamagnetic nanoparticles are attached to the non-spherical reinforcing particles, in a second step the resulting reinforcing particles are introduced into a liquid matrix material and/or a liquid matrix-precursor material, and in a third step the material of the matrix is solidified and/or polymerized and/or cross-linked. In accordance with the proposed invention prior to and/or during solidification and/or polymerization and/or cross-linking of the matrix material or the matrix precursor material, respectively, a magnetic field is applied so as to align the reinforcing particles in the matrix and this alignment is fixed in the matrix during and after the third step, wherein the non-spherical reinforcing particles preferably have a length (l) in one dimension of at least 0.

Abstract: The present invention relates to bone cements and, more particularly, to acrylic-based orthopedic bone cements, their use in spinal applications, and methods for making the same. An embodiment of the present invention provides a method of grafting PMMA brushes on cross-linked PMMA nanospheres comprising at least one of the following steps: performing a hydrolysis reaction of surface methyl ester groups of said cross-linked PMMA nanospheres to form surface carboxylic acid groups of said cross-linked PMMA nanospheres; forming a 2-aminoethyl acrylate compound; coupling said surface carboxylic acid groups of said cross-linked PMMA nanospheres with said 2-aminoethyl acrylate compound to form a coupled compound with an initiating site; and grafting said PMMA brushes onto said initiating site.

Abstract: A radically curable polyurethane composite for dental restorations, including provisional restorations, includes polyurethane dimethacrylate prepolymers that have at least one flexible unit within a polyurethane dimethacrylate backbone, and one or more dimethacrylate monomers. Composite materials made with polyurethane dimethacrylate prepolymers of the invention exhibit superior and optimal properties of flexural strength and deflection-at-break relative to conventional dental resin composites. Composite materials of the invention also provide improved melt-resistance in response to the heat of grinding or finishing, thereby improving the fit of restorations made from the composite and preserving the finishing instruments. Methods of treating a tooth using the radically curable polyurethane composite and methods of making the polyurethane dimethacrylate prepolymers with flexible units is also provided. A kit including the radically curable polyurethane composite is also described.

Abstract: Dental adhesive composition having a pH of at least 5, which comprises an aqueous solution containing (a) a polymerizable N-substituted alkyl acrylic or acrylic acid amide monomer; (b) a water-soluble polymerizable carboxylic acid; and (c) a water-soluble organic solvent.

Abstract: To provide a dual curing type composite resin for core build-up having improved curing property by chemical polymerization with improved mechanical strength of a cured body under the condition of no light irradiation and with a shortened setting time, the composite resin is composed of a first component including a (meth)acrylate polymerizable resin and an organic peroxide, and a second component including (meth)acrylate polymerizable resin and a reducing agent, a photopolymerizaton initiator and a filler are included in the first component and/or the second component, and oxide powder of a Group II element in the periodic table having an average particle diameter of 1 ?m or less is blended in the first component and/or the second component.

Abstract: The present invention provides a curable composition allowing a cured product having high aesthetic quality, strength and durability along with having high surface lubricating property. A curable composition in the present invention comprises: an inorganic powder and a polymerizable monomer, wherein the inorganic powder contains a spherical composite powder, the spherical composite powder has a complex of silicon dioxide and at least one of alumina and zirconia, and an amorphous part and a crystalline part are mixed in the spherical composite powder. A refractive index difference is not more than 0.05 between the spherical composite powder and a cured product obtained by curing only a compound excluded the spherical composite powder.

Abstract: There is provided a dental composition comprising at least one kind of filler and resin matrix, wherein the at least one kind of filler comprises a population of particles, wherein the population of particles has an average particle size from 110 to 500 ?m, the maximum particle size of the population of particles is less than 1.4 times the average particle size, and the D30 of particle size distribution of the population of particles is no less than 0.9 times the average particle size.

Abstract: The present invention provides a curable composition allowing a cured product having high aesthetic quality, strength and durability along with having high surface lubricating property to be formed. The curable composition according to the present invention comprises: an inorganic powder and a polymerizable monomer. The inorganic powder contains a spherical crystallization control powder. The spherical crystallization control powder has a silicon dioxide content in the range of 97 to 100 mass %. An amorphous portion and a crystalline portion are mixed within the spherical crystallization control powder. A refractive index difference is not more than 0.05 between the spherical crystallization control powder and a cured product obtained by curing only constituents other than the spherical crystallization control powder.

Abstract: A dental curable composition has a curing time of 30 seconds to 120 minutes and includes a compound having an acidic group in the molecule (A), a polymerizable monomer (B), an organic amine compound (C) and a sulfur-containing reducing compound (D). In the dental curable composition, the content of the component (A) is 0.01 to 80 parts by weight, the content of the component (B) is 21 to 99.8 parts by weight, the content of the component (C) is 0.01 to 30 parts by weight and the content of the component (D) is 0 to 30 parts by weight. The composition may be cured at a relatively low temperature close to the body temperature without using a peroxide-based polymerization initiator, and has good sealing properties and adhesion.

Abstract: A one-package type tooth surface coating material that is capable of forming, on the surface of a tooth, a cured film having not only a very high strength of adhesion to the tooth surface but also excellent properties such as long-term adhesion, long-term durability, dentinal tubule occlusion and aesthetic appearance, and that has excellent storage stability and can be stored in the form of one package. The one-package type tooth surface coating material includes (A) a polymerizable monomer component containing not less than 5% by mass of an acidic group-containing polymerizable monomer; (B) polyvalent metal ions; (C) a volatile water-soluble organic solvent; (D) water; and (E) an effective amount of a photopolymerization initiator; the amount of the polyvalent metal ions (B) and the amount of the volatile water-soluble organic solvent (C) satisfying a specific relationship.

Abstract: Polymerizable isocyanurate monomers and dental compositions are described. A hardenable dental composition is described comprising at least one isocyanurate monomer that is a stable liquid at about 25° C. The isocyanurate monomer comprises at least one divalent linking group bonded to a nitrogen atom of a trivalent isocyanuric acid ring, wherein the divalent linking group comprises a moiety selected from ester, thioester, ether, or thioether, and combinations of such moieties and a terminal ethylenically unsaturated polymerizable group.

Abstract: The invention provides for a biodegradable synthetic bone composition comprising a biodegradable hydrogel polymer scaffold comprising a plurality of hydrolytically unstable linkages, and an inorganic component; such as a biodegradable poly(hydroxyethylmethacrylate)/hydroxyapatite (pHEMA/HA) hydrogel composite possessing mineral content approximately that of human bone.

Abstract: The present invention includes a novel shapeable material or resin, specifically for dental use. It is an improvement over conventional dental resins because it is strong, safe, does not encourage the propagation of bacteria and contains no bisphenol A (BPA). Also, it is the preferred resiliency for use in the oral cavity.

Abstract: A fracture-resistant denture base material is obtained from an auto-polymerising or cold-polymerising composition containing (A) a liquid monomer component; (B) a powder-shaped component, and (C) at least one initiator or one initiator system for auto- or cold-polymerisation, whereby at least one member of the groups of aliphatic urethane acrylates and aliphatic urethane methacrylates is present in (A) or/and (B); whereby the fracture-resistant material shows, in particular, a fracture toughness of >1.8 MPa*m1/2 and a fracture work of >400 J/m2 after curing, and, preferably also shows a difference in the yellow value, also called b value, of maximally one unit after 8 weeks of storage in fully desalted water at 50° C. Preferably, no synthetic rubber is present.

Abstract: There is disclosed a composition formed by a reaction of at least one component A and at least one component B, wherein component A is selected from the group consisting of a compound comprising at least two thiol-groups and a disulfide derivative of a compound comprising at least two thiol groups, and wherein component B is a compound comprising at least two vinyl groups, for the manufacture of an implant for the treatment of a bone fracture. Advantages include that the adhesive patch formed by the composition will be solid in body fluid upon curing and will exhibit excellent mechanical strength. Advantages include that the composition is biocompatible, the material can be applied in small and inaccessible areas, the process requires less surgeon training, it solves drawback with open surgery, and it is possible to use cost effective materials and methods in the process.

Abstract: A method of producing an improved polyethylene, especially an ultra-high molecular weight polyethylene utilizes a sequential irradiation and annealing process to form a highly cross-linked polyethylene material. The use of sequential irradiation followed by sequential annealing after each irradiation allows each dose of irradiation in the series of doses to be relatively low while achieving a total dose which is sufficiently high to cross-link the material. The process may either be applied to a preformed material such as a rod or bar or sheet made from polyethylene resin or may be applied to a finished polyethylene part.

Abstract: Dental compositions and disulfide monomers are described. The disulfide monomer comprise a disulfide backbone group wherein each of the sulfur atoms are bonded to an ethylenically unsaturated group via a divalent linking group and the linking group comprises at least one heteroatom; and at least one other monomer ethylenically unsaturated monomer.

Abstract: The invention provides an epoxy nanocomposite material for dental therapy, which can be applied to direct or indirect clinical restoration, dental core-post system, and dental brace etc. The epoxy nanocomposite filling material provided by the invention can be polymerized with various curing agents to form the polymer with low shrinkage.

Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.

Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a caseinate. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a caseinate and a hardenable resin or a water-dispersible, polymeric film former are also provided.

Abstract: A glass thread adapted for reinforcing polymeric materials includes a plurality of filaments having a chemical composition that includes the following constituents within the limits defined below in weight percent: SiO2 40 to 60 Al2O3 0 to 5 CaO 1 to 15 MgO 1 to 15 BaO 2 to 15 SrO 12 to 20 ZnO 0.5 to 10 Na2O + K2O + Li2O 0 to 5 TiO2 3 to 20 Prosthetic members including such threads are also described.

Abstract: The invention provides a bone material having a specific surface area of at least 80 m2/g and a protein content of less than 1800 ppm.

Abstract: A reaction-curable adhesive composition exhibiting acidity is formed form a weakly acidic to alkaline composition (I) comprising (a) a polymerizable monomer and (b) a compound represented by the following formula (I) and a strongly acidic composition (II) comprising (a) a polymerizable monomer. R1—C6H4—NR2CH2COOR3??(1) wherein R1 and R2 are each independently a hydrogen atom or an alkyl group which may have a functional group, and R3 is a hydrogen atom or a metal atom. The composition containing the polymerizable monomer can be stably stored for a long period of time.

Abstract: The present invention provides a demineralized bone carrier matrix which is tolerant of bending, stretching and compression. The material comprises a carrier base material cross-linked with a multifunctional polymer. Demineralized bone matrix may be dispersed with the carrier matrix. The demineralized bone carrier matrix may be used as a bone graph substitute. Methods for making the carrier matrix are also provided.

Abstract: The present invention relates to methods for making cross-linked oxidation-resistant polymeric materials and preventing or minimizing in vivo elution of antioxidant from the antioxidant-containing polymeric materials. The invention also provides methods of doping polymeric materials with a spatial control of cross-linking and antioxidant distribution, for example, vitamin E (?-Tocopherol), and methods for extraction/elution of antioxidants, for example, vitamin E (?-tocopherol), from surface regions of antioxidant-containing polymeric materials, and materials used therewith also are provided.

Abstract: The invention relates to a two-component or multicomponent system for producing a dental material, to the use of the system for producing a dental material.

Abstract: The invention features a dental composition containing a polycyclic aromatic compound, such as 2-ethyl 9,10-dimethoxy anthracene (EDMOA), in an amount that provides the composition with fluorescence mimicking that of natural teeth.

Abstract: The invention concerns dental compositions. Said composition comprises (1) a silicone crosslinkable and/or polymerizable by cationic process; (2) an efficient amount of at least an initiator such as an organometallic complex borate; and (3) a dental filler present in the composition in a proportion of at least 10 wt. % relative to the composition total weight. Said dental compositions are useful for making dental prostheses or for dental restoration.

Abstract: The invention provides composite materials prepared by i) providing a fluid formulation comprising (1) at least one compound capable of polymerization and/or cross-linking and (2) a water-consuming reactive filler; ii) optionally injecting said formulation into a site of use; iii) polymerising and/or cross-linking said compound, to form a solid polymer matrix (which may be degradable or non-degradable); iv) causing or allowing said filler to react with water absorbed by said polymer matrix, to produce a solid filler material which is dispersed throughout the composite material. The hydration and formation of the solid filler in situ provides desirable properties to the composites, which have utility for dental composites, bone fillers and adhesives and so on. The composite may also be used to release an active ingredient e.g. an antibacterial or DNA.

Abstract: The invention relates to a dental restorative material which comprises (a) at least one antimicrobially active compound of Formula (I) [AG]m-R1—Z—SP—Y—R2—[WG]p??(I), or a filler that is surface-modified with at least one compound of Formula (I), (b) at least one radically polymerizable monomer and (c) at least one initiator for the radical polymerization. The invention also relates to a use of such dental restorative material for the preparation of an adhesive, primer, cement, coating material or filling material. The invention also relates to a dental material which comprises at least one compound of Formula (I), as well as a use of a compound of Formula (I) for modifying the surface of a substrate selected from ceramic materials, noble and non-noble metals, hard tooth structure, tooth enamel, dentine, collagen, soft tissue, mucous membrane and leather.

Abstract: This invention relates to a composite material for biomedical applications, in particular dental applications, which possesses self-healing capacity and is able to incorporate a system for the release of active ingredients at the stage of application and use.

Abstract: The invention provides methods for inducing reversible chain cleavage of polymer chains in a crosslinked polymeric material or during polymerization of a polymeric material. Reversible cleavage of the polymer backbone is capable of relieving stress in the polymeric material as the bonds reform in a less stressed state. The invention also provides mixtures for making crosslinked polymeric materials, methods for making polymeric materials capable of reversible chain cleavage, materials made by the methods of the invention, and linear monomers containing reversible chain cleavage groups which are useful in the materials and methods of the invention. The mixtures of the invention may be dental restorative compositions used for forming dental restorative materials.

Abstract: This invention relates to polymerizable compositions comprising a salt of a barbituric acid derivative. The compositions are typically shelf-life stable and may be polymerized through mixing of an acidic component with the salt of a barbituric acid derivative.

Abstract: The present invention provides a polymerizable composition that is suitably used as a temporary cement for implant use and a mobile tooth-fixing material. The present invention is a polymerizable composition that includes an acrylic block copolymer (a) having at least one polymer block A that mainly contains a (meth)acrylic acid ester unit and that functions as a hard segment and at least one polymer block B that mainly contains an acrylic acid ester unit and that functions as a soft segment, a polymerizable monomer (b), and a polymerization initiator (c).

Abstract: The present invention relates to a process for the preparation of composites which can be used in the dental field, in which a) mono-or polyfunctional monomers dissolved in a solvent are polymerized to give a polymer gel thoroughly swollen with the solvent, b) the polymer gel produced is subjected to preliminary size reduction, c) a reactive gel is subsequently prepared by the polymer gel, subjected to preliminary size reduction, incorporating a polymerizable monomer or a mixture of polymerizable monomers in the polymer gel while simultaneously removing the solvent, and d) a dental composite is prepared from the reactive gel thus obtained.

Abstract: The present invention generally relates to an artificial bone composition, methods of making the composition, and methods of using the artificial bone. In one aspect, the present invention is directed to a composition for inclusion in artificial bone. The composition includes hydroxyapatite and between 0.5 weight percent and 1.5 weight percent of a polymer. The composition has a microstructure substantially similar to a marine carbonate skeleton.

Abstract: A polymeric composition comprising modified-TiO2 nanoparticles, with or without a solvent, and polymer precursors; wherein the modified-TiO2 nanoparticles comprise titanium dioxide nanoparticles modified with a short-chain unsaturated compound comprising 2 to 10 carbon atoms. The polymeric composition may be used in dental compositions such as dental adhesives, dental composites, and dental sealants.