Abstract: Disclosed are a novel tetrahydroisoquinoline compound, a method for preparing intermediates thereof, a pharmaceutical composition thereof and the use thereof. The tetrahydroisoquinoline compound of the present invention has a good inhibitory effect on phosphodiesterase (PDE4), and can be used in the prevention, treatment or auxiliary treatment of multiple diseases associated with the activity or expression of phosphodiesterase, especially PDE4-associated immune and inflammatory diseases, such as psoriasis and arthritis.

Abstract: A technical problem of the present invention is to provide a condensed polycyclic organic pigment having excellent dispersion properties and dispersion stability. More specifically, the technical problem of the present invention is to provide a condensed polycyclic organic pigment in which a practically sufficient viscosity is achieved in terms of both the initial viscosity of a base ink and the viscosity over time of a base ink when used in the printing ink application. As a result of thorough studies on the surface state of organic pigment particles and interaction among components constituting a printing ink, it has been found that the technical problem can be solved by using a polyvalent metal inorganic salt in a condensed polycyclic organic pigment, thus accomplishing the present invention.

Abstract: The present disclosure relates to Quinacridone pigment and a process of preparation thereof. The Quinacridone pigment of the present disclosure exhibit higher chemical resistance to solvents, higher stability and higher resistance to acid and alkali.

Abstract: Provided are a quinacridone pigment having a low content of a primary aromatic amine, a method for producing the same, and also a gravure and flexo ink, a colorant for plastic, a paint, a lithographic ink, a toner, or an ink-jet ink using the pigment. The quinacridone pigment having a low primary aromatic amine content is provided by washing a quinacridone pigment with at least one solvent selected from water and an organic solvent, or by adding an oxidizing agent to a pigment slurry including a quinacridone pigment and at least one solvent selected from water and an organic solvent to oxidatively decompose the aromatic amine.

Abstract: The present invention relates to phosphorescent organic electroluminescent devices which have a low concentration of the phosphorescent emitter in the emitting layer.

Abstract: A condensed-cyclic compound of Formula 1: wherein, in Formula 1, groups X1, X11 to X14, L21, L22, R21, and R21, and variables a21, a22, b21, b22, c21, and c22 are described in the specification.

Abstract: A heterocyclic compound represented by Formula 1 and an organic light-emitting device including the same. The heterocyclic compound represented by Formula 1 has excellent light emitting characteristics and high charge transporting capabilities.

Abstract: The present invention relates to condensed aromatic compounds with multiple ring bridging of the general formulae (1), (2), (3), (4) and (5). The invention furthermore relates to the use of the compounds according to the invention in an organic electronic device and to a process for the preparation of the compounds according to the invention. The invention furthermore relates to an electronic device which comprises the compounds according to the invention.

Abstract: The present invention describes carbazole derivatives formula (1), where the following applies to the symbols used: Y is on each occurrence, identically or differently, CR or N; X is selected from C(R1)2, O, S, PR1, P(?O)R1 or BR1; characterised in that at least one group R is present which stands, identically or differently on each occurrence, for a group of the following formula (2), and/or in that at least one group R1 is present which stands for a group of the following formula (3) or (4), in particular for use as triplet matrix materials in organic electroluminescent devices. The invention furthermore relates to a process for the preparation of the compounds according to the invention and to electronic devices comprising same.

Abstract: The present invention addresses the problem of providing a new method for increasing the production of fine particles. Using at least two types of fluids to be processed, a raw material fluid containing at least one type of fine particle raw material and a fluid for treating the fine particle raw material, fine particles are obtained by mixing the fluids to be processed in a thin film fluid formed between at least two processing surfaces which are disposed to be faced with each other so as to be able to approach to and separate from each other, at least one of which rotates relative to the other. At this time, the production of the fine particles is increased by introducing the raw material fluid from the centers of the processing surfaces.

Abstract: The present invention provides a novel compound that is capable of largely improving a life span, efficiency, electrochemical stability and thermal stability of an organic light emitting device, and an organic light emitting device in which the compound is included in an organic compound layer.

Abstract: 2,5-di(p-methoxyanilino)terephthalic acid crystal types I and II are made by controlling the pH during the recovery of the oxidized product of the condensation of dimethylsuccinyl succinate with p-methoxyaniline. The resulting 2,5-di(p-methoxyanilino)-terephthalic acid can be converted into 2,9-dimethoxyquinacridone or a solid solution thereof having controlled characteristics.

Abstract: The present invention relates to carboxamide-substituted dyes, the production and use of such dyes as labeling groups in analytics.

Abstract: The present invention relates to polycyclic compounds of the general formula (I) which are distinguished by an amine substituent NR6R7 on the central carbon atom of the chromophore, to processes for their preparation, and to the use thereof for the determination of analytes.

Abstract: A method of preparing a pigment includes in order the steps of: a) providing a pigment containing a nucleophile group under basic conditions; b) reacting the pigment with 1,4-butane sultone or 1,3-propane sultone in an alkaline medium to form sulfobutyl groups respectively sulfopropyl groups on the pigment surface; and c) adding acid to convert the sulfobutyl groups or sulfopropyl groups to sulfonic acid groups. Pigments obtainable by the method and non aqueous pigment dispersions are also disclosed.

Abstract: Novel crystal forms of solid solutions of 2,9-dimethyoxyquinacridone and 2,9-dichloroquinacridone. The crystal forms may be formed by a process comprising the steps of: a) heating a mixture of 2,5-di(4-methoxyanilino)terephthalic acid, and 2,5-di(4-chloroanilino)terephthalic acid in polyphorsphoric acid at a temperature less than 1050 C to form a mixture of 2,9-dimethoxyquinacridone and 2,9-dichloroquinacridone; b) combining the mixture of 2,9-dimethoxyquinacridone and 2,9-dichloroquinacridone with water; and c) heating the mixture of 2,9-dimethoxyquinacridone and 2,9-dichloroquinacridone at a temperature not more than 110° C. Another crystal form may be formed by the process of heating a mixture of 2,9-dimethoxyquinacridone and 2,9-dichloroquinacridone in a polar aprotic solvent. These products are may be used for coloring fibers, plastics, paints, coatings, printing inks, color filters, cosmetics, automotive coatings, textiles, fibers, powder coatings, in-mold coatings, laminate films, and the like.

Abstract: A heterocyclic compound represented by Formula 1 below, and an organic light-emitting diode including the heterocyclic compound, and a flat display device including the organic light-emitting diode. wherein Ar1 to Ar4, X1, X2, Y1, Y2, L1, and m are defined as in the specification.

Abstract: A quinacridone pigment composition contains quinacridone microparticles which have durability and spectral characteristics equivalent to those required for a magenta color of a dye. The quinacridone pigment composition contains at least one type of quinacridone microparticles, wherein a difference between the maximum transmittance (Tmax1) and the minimum transmittance (Tmin) is 80% or more in a transmission spectrum at 350 nm to 800 nm and the difference between the maximum and minimum transmittance is 30% or more in a transmission spectrum at 350 nm to 580 nm, or the difference between the maximum transmittance (Tmax1) and the minimum transmittance (Tmin) is 80% or more in a transmission spectrum at 350 nm to 800 nm and the wavelength (?max) at which the transmittance in a transmission spectrum at 350 nm to 500 nm becomes maximum is less than 430 nm. A method is provided for producing the quinacridone microparticles.

Abstract: 2,5-di(p-methoxyanilino)terephthalic acid crystal types I and II are made by controlling the pH during the recovery of the oxidized product of the condensation of dimethylsuccinyl succinate with p-methoxyaniline. The resulting 2,5-di(p-methoxyanilino)-terephthalic acid can be converted into 2,9-dimethoxyquinacridone or a solid solution thereof having controlled characteristics.

Abstract: The present invention relates to compounds useful for measuring aromatase activity. The invention further provides methods for measuring aromatase activity and for screening test agents which modulate aromatase activity. A kit is also provided for use in such screening methods.

Abstract: A heterocyclic compound includes compounds represented by Formula 1 or Formula 2 below:

Abstract: A method for manufacturing a dispersion of a quinoline derivative that is dispersed at a high concentration and has a small particle size. The method includes the steps of preparing a solution by dissolving an N-arylanthranilic acid derivative in an organosulfonic acid, heating the solution and obtaining a reaction liquid in which a quinoline derivative has been produced by a condensation ring-closing reaction, and obtaining a dispersion of the quinoline derivative by mixing the reaction liquid with an aqueous solution. The step of mixing the reaction liquid with an aqueous solution may be performed in a mixing field having a micro-channel.

Abstract: A method of preparing a pigment includes in order the steps of: a) providing a pigment containing a nucleophile group under basic conditions; b) reacting the pigment with 1,4-butane sultone or 1,3-propane sultone in an alkaline medium to form sulfobutyl groups respectively sulfopropyl groups on the pigment surface; and c) adding acid to convert the sulfobutyl groups or sulfopropyl groups to sulfonic acid groups. Pigments obtainable by the method and non aqueous pigment dispersions are also disclosed.

Abstract: A method of preparing a pigment includes the steps of: a) providing a mixture including: a pigment selected from the group of pigments including at least 50 wt % of C.I. Pigment Violet 23, C.I. Pigment Red 146, C.I. Pigment Red 176, C.I. Pigment Red 177, C.I. Pigment Violet 19 and C.I. Pigment Orange 13 based on the total weight of the pigment; alkyl nitrile; and at least one acid selected from the group consisting of sulfuric acid and chlorosulfuric acid, with the acid present in the mixture in amount of more than 2 wt % based on the total weight of the pigment; b) heating the mixture for more than 2 hours to a temperature of at least 70° C.; and c) filtering the mixture and washing the filtrand with a washing liquid containing water until the filtrate has a pH between 4 and 7. Pigments obtainable by the method and non aqueous pigment dispersions are also disclosed.

Abstract: Novel crystal forms of solid solutions of 2,9-dimethyoxyquinacridone and 2,9-dichloroquinacridone. The crystal forms may be formed by a process comprising the steps of: a) heating a mixture of 2,5-di(4-methoxyanilino)terephthalic acid, and 2,5-di(4-chloroanilino)terephthalic acid in polyphorsphoric acid at a temperature less than 1050 C to form a mixture of 2,9-dimethoxyquinacridone and 2,9-dichloroquinacridone; b) combining the mixture of 2,9-dimethoxyquinacridone and 2,9-dichloroquinacridone with water; and c) heating the mixture of 2,9-dimethoxyquinacridone and 2,9-dichloroquinacridone at a temperature not more than 110° C. Another crystal form may be formed by the process of heating a mixture of 2,9-dimethoxyquinacridone and 2,9-dichloroquinacridone in a polar aprotic solvent. These products are may be used for coloring fibers, plastics, paints, coatings, printing inks, color filters, cosmetics, automotive coatings, textiles, fibers, powder coatings, in-mold coatings, laminate films, and the like.

Abstract: An organic semiconducting layer formulation containing an organic binder which has a permittivity, ?, at 1,000 Hz of 3.3 or less and a polyacene compound of Formula A: and processes for the preparation thereof and uses thereof in various electronic devices.

Abstract: Disclosed are an organic electronic device and a compound thereof, and a terminal.

Abstract: Disclosed is a metal complex compound represented by the following Chemical Formula 1, and an organic light emitting diode device including the same. In Chemical Formula 1, M, R1 to R8, A1 to A6, and y are the same as defined in the detailed description.

Abstract: A method of producing a modified pigment by sulfonating a pigment and subsequently oxidizing the pigment. The modified pigment may have sulfonic acid and carboxyl surface modifying groups attached to the surface of the pigment. Charge balancing counterions such as alkali metals, alkaline earth metals and NR1R2R3H+, where R1, R2 and R3 are independently H or C1-C5 alkyl groups, may be associated with the surface modifying groups. The modified pigment is combined with water to produce a dispersion that can be used in such applications as coatings, paints, papers, adhesives, latexes, toners, textiles, fibers, plastics and inks.

Abstract: The invention provides compounds of formula I: wherein A, B, W, Y, Z, and R1 have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I.

Abstract: An organic electroluminescent element including at least an emission layer sandwiched between an anode and a cathode, wherein the emission layer comprises at least a compound represented by Formula (A),

Abstract: The present invention relates to compounds useful for measuring aromatase activity. The invention further provides methods for measuring aromatase activity and for screening test agents which modulate aromatase activity. A kit is also provided for use in such screening methods.

Abstract: Disclased is a polymeric compound having a constitutional unit represented by formula (1a), wherein ring A and ring B independently represent an aromatic hydrocarbon ring which may have a substituent; R1 represents a group represented by formula (2); and R2 represents an aryl group or a monovalent aromatic heterocyclic group which may be substituted by an alkyl group or the like. In formula (2), Ar1 to Ar3 independently represent an arylene group or a divalent group to which two or more arylene groups are attached via a single bond; Ar4 to Ar7 independently represent an aryl group or a monovalent aromatic heterocyclic group; R6 represents a hydrogen atom, an alkyl group, an aryl group or a monovalent aromatic heterocyclic group; Ar1 to Ar7 and R6 may be substituted by an alkyl group or the like; and k and kk independently represent an integer of 0 to 3, provided that at least one of k and kk represents an integer of 1 to 3.

Abstract: A method is provided for pigment dispersion. The method includes preparing a solution in which the pigment is dissolved in an organic acid, preparing a reaction liquid capable of decreasing the solubility of the pigment in the solution, and mixing the solution and the reaction liquid in the presence of an additive represented by a General Formula (1) below, CmH2m+1(OCH2CH2)nOH??(1) wherein m is an integer higher than 14 and lower than 18, and n is an integer equal to or higher than 15 and equal to or lower than 25.

Abstract: It is an object of the present invention to provide a novel material that can be used for an electron injecting material. In addition, it is an object of the present invention to provide a light-emitting element that is able to broaden choices for an electrode material. An aspect of the present invention is an electron injecting material represented by a general formula (2). In the general formula (2), R6 is selected from the group consisting of an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 1 to 4 carbon atoms, and an aryl group having 6 to 10 carbon atoms, where the alkenyl group and the aryl group may have a substituent.

Abstract: The present application relates to compounds of formula A(D)x(E)y, (I), compounds of formula (III), compounds of formula (X), as well as processes for the preparation thereof, processes where the compounds (I) are converted to pigments of formula (II) and the use of the compounds (I).

Abstract: A sulfonated derivative of an organic pigment moiety comprising a polyetheramine, and a metal or ammonium salt. The pigment is used for coloration of printing inks and coatings. For ink-jet systems there is excellent filterability, low viscosity, and stability thereof.

Abstract: A novel semiconductor device comprises an azaperylene organic semiconductor of the formula I wherein the substitutents are defined herein.

Abstract: The present invention relates to a method of preparing a yellow pigment comprising an asymmetric quinolonoquinolone in an amount greater than 50% by weight of the yellow pigment. Also disclosed are modified yellow pigments comprising this yellow pigment having attached at least one organic group as well as inkjet ink compositions comprising the yellow pigments or the modified yellow pigments.

Abstract: The present invention concerns novel dibenzo[c,h][1,5]naphthyridine of formula (I) and their use as DNA probes, as well as the methods for marking DNA using the same.

Abstract: The invention provides low molecular weight or polymeric organic materials in which at least one hydrogen atom is replaced by a group of the formula (A) where R is alkyl group, alkoxyalkyl group, alkoxy group, thioalkoxy group, aryl group or alkenyl group, in each of which one or more hydrogen atoms may be replaced and one or more nonadjacent carbon atoms may be replaced. Z is —O—, —S—, —CO—, —COO—, —O—CO— or a bivalent group —(CR1R2)n— in which R1 and R2 are hydrogen, alkyl, alkoxy, alkoxyalkyl or thioalkoxy group, aryl or alkenyl, in each of which one or more hydrogen atoms may be replaced and one or more nonadjacent carbon atoms may be replaced, and n is an integer from 1 to 20. X is a bivalent group —(CR1R2)n— and, with the proviso that the number of these A groups is limited by the maximum number of available substitutable hydrogen atoms.

Abstract: A quinacridone derivative according to Formula (I): wherein R1 and R2 are each independently selected from the group consisting of hydrogen, alkyl, and halogen. Also, methods for preparing non-aqueous pigment dispersions and inkjet inks including a pigment and the quinacridone derivative of Formula (I).

Abstract: A compound of formula 9 and uses thereof in various electronic devices and in a formulation for ink jet printing and in an organic semiconducting layer formulation.

Abstract: 2,5-di(p-methoxyanilino)terephthalic acid crystal types I and II are made by controlling the pH during the recovery of the oxidized product of the condensation of dimethylsuccinyl succinate with p-methoxyaniline. The resulting 2,5-di(p-methoxyanilino)-terephthalic acid can be converted into 2,9-dimethoxyquinacridone or a solid solution thereof having controlled characteristics.

Abstract: A process for preparing coated nanoscale quinacridone pigment particles, includes: mixing a quinacridone pigment precursor or crude quinacridone pigment with a first solution including an acid to form nanoscale quinacridone pigment particles; adding the first solution and formed nanoscale quinacridone pigment particles into a second solution including deionized water to form a third solution and to precipitate the nanoscale quinacridone pigment particles; and washing the precipitated nanoscale quinacridone pigment particles in a fourth solution including a surface additive compound, whereby the surface additive compound coats the nanoscale quinacridone pigment particles; wherein the surface additive compound is a rosin compound.

Abstract: A process for preparing coated nanoscale quinacridone pigment particles, includes providing a first solution containing a surface additive compound in an acid; adding a quinacridone pigment precursor or crude quinacridone pigment into the first solution and causing the surface additive compound to coat formed nanoscale quinacridone pigment particles; and adding the first solution and coated nanoscale quinacridone pigment particles into a second solution containing deionized water to form a third solution and to precipitate the coated nanoscale quinacridone pigment particles; wherein the surface additive compound is a rosin compound.

Abstract: A quinacridone derivative according to Formula (I): wherein R1 and R2 are each independently selected from the group consisting of hydrogen, alkyl, and halogen. Also, methods for preparing non-aqueous pigment dispersions and inkjet inks including a pigment and the quinacridone derivative of Formula (I).

Abstract: Disclosed are compounds having Formula I: and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, A, and B are as defined herein, for use in methods for treating, preventing or ameliorating hyperproliferative disorders, such as cancer and other diseases and conditions. The invention also relates to pharmaceutical compositions and formulations comprising a compound having Formula I, and in combination with one or more other active agents and/or treatments.

Abstract: A nanoscale pigment particle composition includes a quinacridone pigment including at least one functional moiety, and a sterically bulky stabilizer compound including at least one functional group, wherein the functional moiety associates non-covalently with the functional group; and the presence of the associated stabilizer limits the extent of particle growth and aggregation, to afford nanoscale-sized particles.

Abstract: A nanoscale pigment particle composition includes a quinacridone pigment having at least one functional moiety, and a sterically bulky stabilizer compound having at least one functional group, wherein the functional moiety associates non-covalently with the functional group; and the presence of the associated stabilizer limits the extent of particle growth and aggregation, so as to afford nanoscale-sized particles of the pigment.