Double Bond Between Ring Members Of The Lactone Ring Or Chalcogen Double Bonded Directly At The 3- Or 4-position Of The Lactone Ring (e.g., Ascorbic Acid, Etc.) Patents (Class 549/315)
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Patent number: 11097206Abstract: Disclosed is a continuous process for the purification of steviol glycosides such as Rebaudioside D and/or Rebaudioside M extracted from the dried stevia leaves or extracted from a fermentation broth using continuous simulated moving bed processes and nanofiltration without the addition of organic solvents to obtain a purified steviol product comprising sweet steviol glycosides. The sweet steviol glycosides can be used as substitutes for caloric sweeteners in beverages and in other food items.Type: GrantFiled: October 11, 2019Date of Patent: August 24, 2021Assignee: Orochem Technologies Inc.Inventors: Babu Siddegowda Antharavally, Anil R. Oroskar, Asha A. Oroskar
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Patent number: 10413894Abstract: This invention discloses a method for preparing a catalyst for catalyzing the degradation of organic pollutants in printing and dyeing wastewater by ozone, wherein the catalyst comprises a porous carbon material as a substrate and metal oxide nanoparticles deposited on the surface of the substrate. The method comprises the steps of: allowing a mixture of resorcinol, formaldehyde, trimethylhexadecyl ammonium bromide, multi-walled carbon nanotubes and deionized water to react to form cured product, which is then calcinated and carbonized at high temperature to produce the porous carbon material; impregnating the resulting porous carbon material with nitrate solution, drying the porous carbon material, and calcinating it at high temperature, wherein the absorbed nitrate is decomposed into metal oxide and embedded into the porous carbon material.Type: GrantFiled: May 26, 2016Date of Patent: September 17, 2019Assignee: The Hong Kong Research Institute of Textiles and Apparel LimitedInventors: Songmin Shang, Enling Hu, Xiao-ming Tao
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Patent number: 9023889Abstract: The invention relates to the use of at least one ascorbic acid derivative for the fictionalization of matrices, and to specific ascorbic acid derivatives and processes for the preparation thereof.Type: GrantFiled: June 27, 2007Date of Patent: May 5, 2015Assignee: Merck Patent GmbHInventors: Thomas Rudolph, Philipp Buehle, Herwig Buchholz
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Patent number: 8957111Abstract: A compound of formula (ascorbate)2Sr:(M+a)x(ascorbate)y, or ascorbate)2Sr:Ca(ascorbate)2, a composition containing the same, a method of making the same and a method of administering the same as a supplement.Type: GrantFiled: February 11, 2013Date of Patent: February 17, 2015Assignee: Nutraceutical CorporationInventors: Shayne Morris, Richard Bush
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Publication number: 20150045426Abstract: A complex formed of at least one molecule of 5-(1,2-dihydroxy-ethyl)-3,4-dihydroxy-5H-furan-2-one or a derivative covalently bonded with at least one hydrocarbon radical with formula (A) as follows: wherein: •-m 1=1, 2, 3, 4, 5 or 6; •-m 2=0, 1, 2, 3, 4, 5 or 6; and represents the site of the bond with the molecule of 5-(1,2-dihydroxy-ethyl)-3,4-dihydroxy-5H-furan-2-one or derivative.Type: ApplicationFiled: March 14, 2013Publication date: February 12, 2015Inventors: Patrick Couvreur, Fatima Zouhiri, Ruxandra Gref, Didier Desmaele
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Patent number: 8946280Abstract: The present invention relates to novel strigolactam derivatives of formula (I) to processes and intermediates for preparing them, to plant growth regulator compositions comprising them and to methods of using them for controlling the growth of plants and/or promoting the germination of seeds.Type: GrantFiled: December 9, 2011Date of Patent: February 3, 2015Assignee: Syngenta Participations AGInventors: Mathilde Denise Lachia, Alain De Mesmaeker, Hanno Christian Wolf, Pierre Joseph Marcel Jung
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Publication number: 20150011138Abstract: The present invention provides a composition, a gypsum board and their preparation method and the use of ascorbic acid as an anti-sagging additive in a gypsum board. Said gypsum board comprises set gypsum prepared from the composition; while said composition comprises hemi-hydrate gypsum, water and a compound comprising group and no carboxylate groups. The set gypsum prepared from the said composition shows better anti-sagging or deformation resisting property. The gypsum board of the present invention is hardly distorted and has stronger stability even in the condition of high humidity, thus improve the quality of the gypsum board to meet the demands of the customer.Type: ApplicationFiled: December 3, 2012Publication date: January 8, 2015Applicant: SAINT-GOBAIN PLACOInventors: Xiaotong Gao, Huifen Li, Hao Song, Ke Zhang
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Publication number: 20140309415Abstract: The present invention is directed to methods for preparing sorbose from glucose, said method comprising: (a) contacting the glucose with a silica-containing structure comprising a zeolite having a topology of a 12 membered-ring or larger, an ordered mesoporous silica material, or an amorphous silica, said structure containing Lewis acidic Ti4+ or Zr4+ or both Ti4+ and Zr4+ framework centers, said contacting conducted under reaction conditions sufficient to isomerize the glucose to sorbose. The sorbose may be (b) separated or isolated; or (c) converted to ascorbic acid.Type: ApplicationFiled: March 5, 2014Publication date: October 16, 2014Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGYInventors: MARK E. DAVIS, RAJAMANI GOUNDER
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Patent number: 8841465Abstract: The present invention relates to a method for selective functionalization of metallic single-walled carbon nanotubes with a diazonium derivative. The present invention also relates to the use of the mixture of metallic single-walled carbon nanotubes selectively functionalized and to the semiconducting single-walled carbon nanotubes obtained by means of the method according to the invention, for producing transistor channels in particular in electronics, electron acceptor materials, in particular in photovoltaic systems, nonlinear infrared photon emitters or absorbers, current-conducting electrodes, flexible transparent electrodes, antistatic coatings, chemical detectors, and solar cells.Type: GrantFiled: June 7, 2012Date of Patent: September 23, 2014Assignee: Commissariat a l'Energie Atomique et aux Energies AlternativesInventor: Pascale Chenevier
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Publication number: 20140235684Abstract: A metal-salen complex compound responsive drug, which has an antidotal property capable of neutralizing cytotoxicity of a metal-salen complex compound, and an intra-corporeal behavior control system for the metal-salen complex compound are provided. This metal-salen complex compound responsive drug contains an effective amount of a metal chelating agent to suppress side effects by the metal-salen complex compound.Type: ApplicationFiled: September 19, 2012Publication date: August 21, 2014Inventors: Yoshihiro Ishikawa, Haruki Eguchi
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Publication number: 20140194536Abstract: The present invention relates to a liquid crystal compound that can be used as a base for injection formulations. The present invention provides an amphipathic compound having the following general formula (I): wherein X and Y each denotes a hydrogen atom or together denote an oxygen atom, n denotes an integer from 0 to 2, m denotes the integer 1 or 2, and R denotes a hydrophilic group generated by removal of one hydroxyl group from any one selected from the group consisting of glycerol, erythritol, pentaerythritol, diglycerol, triglycerol, xylose, sorbitol, ascorbic acid, glucose, galactose, mannose, dipentaerythritol, maltose, mannitol, and xylitol; as well as a base for injection formulations and depot formulation comprising the same.Type: ApplicationFiled: February 28, 2014Publication date: July 10, 2014Applicant: Chemgenesis IncorporatedInventors: Yutaka Ikeda, Jun Yamashita, Ichiro Hijikuro, Satoshi Imuta, Yasuhiro Hiroki, Takashi Takahashi
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Patent number: 8759030Abstract: The object of the present invention is to provide a method and a process for producing 2-O-?-glucopyranosyl-L-ascorbic acid where 5-O-?-glucopyranosyl-L-ascorbic acid and 6-O-?-glucopyranosyl-L-ascorbic acid are not formed or formed in such a small amount that the formation of these can nor be detected. The present invention solves the above object by providing a process for producing 2-O-?-glucopyranosyl-L-ascorbic acid comprising the steps of allowing ?-isomaltosyl glucosaccharide-forming enzyme together with or without cyclomaltodextrin glucanotransferase (EC 2.4.1.19) to act on a solution comprising L-ascorbic acid and, an ?-glucosyl saccharide to form 2-O-?-glucopyranosyl-L-ascorbic acid and collecting the formed 2-O-?-glucopyranosyl-L-ascorbic acid.Type: GrantFiled: July 7, 2003Date of Patent: June 24, 2014Assignee: Hayashibara Co., Ltd.Inventors: Kazuhisa Mukai, Keiji Tsusaki, Michio Kubota, Shigeharu Fukuda, Toshio Miyake
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Publication number: 20140114079Abstract: The present invention relates to a method for selective functionalization of metallic single-walled carbon nanotubes with a diazonium derivative. The present invention also relates to the use of the mixture of metallic single-walled carbon nanotubes selectively functionalized and to the semiconducting single-walled carbon nanotubes obtained by means of the method according to the invention, for producing transistor channels in particular in electronics, electron acceptor materials, in particular in photovoltaic systems, nonlinear infrared photon emitters or absorbers, current-conducting electrodes, flexible transparent electrodes, antistatic coatings, chemical detectors, and solar cells.Type: ApplicationFiled: June 7, 2012Publication date: April 24, 2014Applicant: Commissariat A L'Energie Atomique et aux Energies AlternativesInventor: Pascale Chenevier
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Publication number: 20140113963Abstract: An antibiotic composition including erythorbyl laurate as an active ingredient and a use thereof are disclosed. Erythorbyl laurate is confirmed to have antibiotic effects on Gram-positive bacteria and thus is used as an antibiotic agent in foods, cosmetics, feeds, and the like and utilized in the form of a hand cleaner and other medicines for external application.Type: ApplicationFiled: February 28, 2013Publication date: April 24, 2014Applicant: SNU R&DB FoundationInventors: Pahn Shick Chang, Kyung Min Park, Da Eun Lee, Dong Hyun Kang
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Publication number: 20140011845Abstract: Disclosed are cyclic dione derivatives represented by formula (I), wherein the substituents are as defined in the description. The preparation method, intermediate and use thereof are also provided.Type: ApplicationFiled: December 30, 2011Publication date: January 9, 2014Applicant: SYNGENTA PARTICIPATIONS AGInventors: Stephane Andre Marie Jeanmart, Long Lu, Yaming Wu, Lisheng Mao, Michel Muehlbeach
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Patent number: 8598228Abstract: The invention relates to specific cinnamic acid ascorbates and to the use thereof as UV filters which bond to the skin, and to a process for the preparation thereof, and to preparations comprising these compounds.Type: GrantFiled: April 12, 2010Date of Patent: December 3, 2013Assignee: Merck Patent GmbHInventors: Thomas Rudolph, Philipp Buehle
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Publication number: 20130237509Abstract: A compound of formula (ascorbate)2Sr:(Ma)x(ascorbate)y, or ascorbate)2Sr:Ca(ascorbate)2, a composition containing the same, a method of making the same and a method of administering the same as a supplement.Type: ApplicationFiled: February 11, 2013Publication date: September 12, 2013Applicant: NUTRACEUTICAL CORPORATIONInventors: Shayne Morris, Richard Bush
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Publication number: 20130228192Abstract: The invention relates to the use of specific ascorbic acid derivatives for dyeing keratin-containing fibres or as direct dyes for the preparation of a composition for dyeing keratin-containing fibres, and to methods for dyeing keratin-containing fibres, in particular for dyeing human hair.Type: ApplicationFiled: October 19, 2011Publication date: September 5, 2013Applicant: MERCK PATENT GMBHInventors: Thomas Rudolph, Michaela Oberle
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Publication number: 20130171271Abstract: Methods for treating cancers, tumors, and neoplasms using a composition comprising one or more generally regarded as safe (GRAS) compounds selected from the group of components consisting of vitamins, selenium, fatty acids, fatty acid salts, and fatty acid esters, and mixtures of two or more said components, either as a stand-alone treatment or in combination with one or more anti-cancer drugs or devices or other anti-neoplastic agents, treatments, or devices are provided. In some instances, concomitant hyperthermia therapy is employed. Also provided are compositions and kits containing the compositions, for implement various aspects of the invention.Type: ApplicationFiled: July 25, 2011Publication date: July 4, 2013Applicant: CHEMOTHERAPEUTICS, LLCInventors: Gary Keeling, Keith B. Hoffman
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Publication number: 20130149250Abstract: The present invention provides a MRI probe of use in detecting and characterizing redox systems in vivo. Also provided are methods of using the probe in MR imaging experiments for diagnosis of disease in a subject, for drug discovery and for probing the redox states of biological systems in vitro.Type: ApplicationFiled: June 25, 2012Publication date: June 13, 2013Applicant: The Regents of the University of CaliforniaInventors: David M. WILSON, Kayvan KESHARI, John KURHANEWICZ, Daniel VIGNERON
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Patent number: 8404743Abstract: Disclosed are compounds comprising a zinc oxide molecule chemically bound to one or more molecules having an acidic hydrogen, such as an organic acid. The invention also provides compositions comprising such compounds and methods of preparing such compounds. The compounds of the invention may be provided in, for example, topical skin formulations, pharmaceutical compositions, or delivery systems for active ingredients.Type: GrantFiled: October 31, 2011Date of Patent: March 26, 2013Assignee: Mary Kay Inc.Inventor: James Swanzy
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Patent number: 8383837Abstract: The invention relates to a process for the catalytic conversion of a carbohydrate, an alcohol, an aldehyde or a polyhydroxy compound in the presence of a catalyst containing gold in a solvent.Type: GrantFiled: June 5, 2008Date of Patent: February 26, 2013Assignee: DSM IP Assets B.V.Inventors: Werner Bonrath, Jocelyn Fischesser
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Patent number: 8378126Abstract: A compound of formula (ascorbate)2Sr:(M+a)x(ascorbate)y, or ascorbate)2Sr:Ca(ascorbate)2, a composition containing the same, a method of making the same and a method of administering the same as a supplement.Type: GrantFiled: August 1, 2008Date of Patent: February 19, 2013Assignee: Nutraceutical CorporationInventors: Shayne Morris, Richard Bush
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Patent number: 8372992Abstract: A compound of formula (ascorbate)2Sr:(M+a)x(ascorbate)y, or ascorbate)2Sr:Ca(ascorbate)2, a composition containing the same, a method of making the same and a method of administering the same as a supplement.Type: GrantFiled: June 2, 2008Date of Patent: February 12, 2013Assignee: Nutraceutical CorporationInventors: Richard Bush, Shayne Morris
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Publication number: 20120294866Abstract: The present invention provides a liquid pharmaceutical formulation comprising a therapeutic protein, a surfactant and at least an antioxidant selected from the group of radical scavengers, chelating agents or chain terminators.Type: ApplicationFiled: January 14, 2010Publication date: November 22, 2012Applicant: F. HOFFMANN-LA ROCHE AGInventors: Hanns-Christian Mahler, Satya Krishna Kishore Ravuri
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Publication number: 20120277180Abstract: Provided herein are methods and systems for identifying one or more cofactors such as vitamins for individuals based on the genetic makeup of the individual by detecting the presence or absence of at least one genetic variant, determining a predisposition to cofactor remediable condition, generating a personalized nutritional advice plan based on the genetic variant. Also provided herein are formulations of cofactors determined by the genetic make-up of the individual and methods of determining and producing these formulations.Type: ApplicationFiled: September 30, 2010Publication date: November 1, 2012Applicants: VITAPATH GENETICS, INC, THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Nicholas Marini, Jasper Rine, Dennis Austin Gilbert, Bruce Cohen
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Patent number: 8278350Abstract: An agent for skin external use of the invention contains a salt of higher fatty acid ester of ascorbic acid-2-phosphoric acid ester and a polyhydric alcohol. According to the present invention, occurrence of turbidity or precipitation with time can be prevented to enhance stability even when the agent for skin external use is prepared using a specific salt of higher fatty acid ester of ascorbic acid-2-phosphoric acid ester. Therefore, the present invention is useful for all agents for skin external use, particularly cosmetics.Type: GrantFiled: October 13, 2004Date of Patent: October 2, 2012Assignee: Showa Denko K.K.Inventors: Eiko Kato, Tadashi Yoneda, Eiji Ogata
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Publication number: 20120220580Abstract: Compounds having the structure of general formula I or pharmaceutically acceptable salts thereof which are derivatives of fucoxanthin and fucoxanthol are disclosed. A preparation method of the compound and its use in weight reducing are also disclosed.Type: ApplicationFiled: April 19, 2012Publication date: August 30, 2012Applicant: BEIJING GINGKO GROUP BIOLOGICAL TECHNOLOGY CO., LTD.Inventors: YANMEI LI, QINGHUA LIU
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Patent number: 8242169Abstract: An emulsion composition of the present invention includes (A) a salt of a higher fatty acid ester of ascorbic acid-2-phosphoric acid ester, (B) a polyglycerin fatty acid monoester including polyglycerin having a mean polymerization degree of 8 to 12 and an unsaturated fatty acid residual group of 14 to 22 carbon atoms, (C) a polyglycerin fatty acid monoester comprising polyglycerin having a mean polymerization degree of 2 to 6 and an unsaturated fatty acid residual group of 14 to 22 carbon atoms, and (D) a hydrocarbon oil, wherein the blending ratio by mass between the component (B) and the component (C) is in the range of 1:1 to 3:1, and the blending ratio by mass between the total of the components (B) and (C) and the component (D) is in the range of 10:1 to 1:4.Type: GrantFiled: July 3, 2007Date of Patent: August 14, 2012Assignee: Showa Denko K.K.Inventors: Tadashi Yoneda, Naoko Ito, Kazuo Furuya
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Publication number: 20120172580Abstract: The present invention provides an anti-plant virus agent which exhibits preventative and therapeutic effects on plant virus diseases. The anti-plant virus agent of the present invention is characterized by containing at least one compound selected from the group consisting of ascorbic acid derivatives represented by Formula (I) (wherein, R1 to R4 each independently represents a hydrogen atom, —SO3H, —PO3H2, a glycosyl group, or —COR11, wherein R11 represents an unsubstituted or substituted C1-30 alkyl group, or an unsubstituted or substituted C2-30 alkenyl group, with the proviso that R1 to R4 may not all be hydrogen atoms at the same time), and salts thereof.Type: ApplicationFiled: September 9, 2010Publication date: July 5, 2012Applicants: Nippon Soda Co., Ltd., National University Corporation hokkaido University Kita 8-jyo Nishi 5-chomeInventors: Chikara Masuta, Hanako Shimura, Shinsuke Sano, Takako Fukagawa
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Publication number: 20120157370Abstract: The invention relates to the use of radical traps in detergents and cleaners in order to improve cleaning performance, in particular for dirt containing polymerizable dyes.Type: ApplicationFiled: February 23, 2012Publication date: June 21, 2012Applicant: Henkel AG & Co. KGaAInventors: Christian Kropf, Andreas Buhl, André Hätzelt
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Patent number: 8198321Abstract: The invention relates to a terpenic composition for use as an anti-micro-organism or anti-viral agent comprising a cyclic terpenic compound obtained from a terpene of the general formula (C5H8)n, n being in the range of 2 to 5; and to a vector-forming organic substance, associated to the said cyclic terpenic compound.Type: GrantFiled: November 16, 2007Date of Patent: June 12, 2012Inventor: Aurèle Henri Mannarini
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Patent number: 8163939Abstract: Disclosed is an ascorbic acid derivative or a salt thereof wherein at least one of hydrogen atoms in hydroxy groups at the 2-position and the 3-position of ascorbic acid is substituted by R—O—CH2—CH(OH)—CH2—, R—O—CH2—CH(CH2OH)—, R—CH(CH2OH)—, R—CH(OH)—CH2— (wherein R represents an alkyl group, an alkenyl group or a phenyl group), or a hydroxycyclohexyl group. Also disclosed is a method for producing an ascorbic acid derivative or a salt thereof, which is characterized by reacting ascorbic acid with an epoxy compound such as an alkyl glycidyl ether, an epoxy alkane or an alicyclic epoxy.Type: GrantFiled: August 21, 2008Date of Patent: April 24, 2012Assignee: Seikwa Kasei Company, LimitedInventors: Masato Yoshioka, Norihisa Taira, Akane Kamiyama, Keiichi Uehara, Naoya Hashimoto
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Publication number: 20120077992Abstract: The present invention relates to a device for treatment of material transported through the device comprising at least one porous element consisting of solid, for example metallic, structure which allows cross-flow of the material through the porous element. The invention also relates to various types of uses of the device. A device in accordance with the invention is particularly useful to carry out chemical reactions under homogenous and heterogeneous conditions. Such a device hereinafter also referred as reactor may comprises a tube (1) having a cylindrical wall (2) with one inlet end (3) and one outlet end (4). Arranged in the tube (1) is at least one cylindrical porous element (5) consisting of solid metal structure, wherein said porous element (5) comprises a plurality of hollow spaces that are connected to each other and form an interconnected cavity network and wherein the at least one porous element (5) and the cylindrical wall (2) are made in one piece.Type: ApplicationFiled: June 14, 2010Publication date: March 29, 2012Inventors: Cédric Hutter, Francesco Mascarello, Philipp Von Rohr, David Ruppen
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Publication number: 20120052028Abstract: The invention relates to specific cinnamic acid ascorbates and to the use thereof as UV filters which bond to the skin, and to a process for the preparation thereof, and to preparations comprising these compounds.Type: ApplicationFiled: April 12, 2010Publication date: March 1, 2012Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNGInventors: Thomas Rudolph, Philipp Buehle
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Publication number: 20110306133Abstract: Disclosed are a culture medium, an additive, and a method for efficiently inducing the differentiation of mammalian somatic stem cells into cells having the characteristics of adipocytes under conditions of serum-free or low-serum culture medium. The culture medium for inducing the differentiation of mammalian somatic stem cells into adipocytes comprises a basal medium for culturing mammalian cells, an agent for inducing the differentiation of mammalian somatic stem cells into adipocytes, biotin, a ligand for endothelial cell differentiation gene (Edg) family receptors, vitamin C, and HEPES, which culture medium is serum-free or contains a low concentration of serum.Type: ApplicationFiled: February 18, 2010Publication date: December 15, 2011Inventor: Yoshiyuki Hotta
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Publication number: 20110059034Abstract: Disclosed is an ascorbic acid derivative or a salt thereof wherein at least one of hydrogen atoms in hydroxy groups at the 2-position and the 3-position of ascorbic acid is substituted by R—O—CH2—CH(OH)—CH2—, R—O—CH2—CH(CH2OH)—, R—CH(CH2OH)—, R—CH(OH)—CH2— (wherein R represents an alkyl group, an alkenyl group or a phenyl group), or a hydroxycyclohexyl group. Also disclosed is a method for producing an ascorbic acid derivative or a salt thereof, which is characterized by reacting ascorbic acid with an epoxy compound such as an alkyl glycidyl ether, an epoxy alkane or an alicyclic epoxy.Type: ApplicationFiled: August 21, 2008Publication date: March 10, 2011Inventors: Masato Yoshioka, Norihisa Taira, Akane Kamiyama, Keiichi Uehara, Naoya Hashimoto
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Publication number: 20110021626Abstract: The invention relates to a conjugated dendrimer that comprises at least one water-soluble dendrimer and at least one vitamin C molecule. The conjugated dendrimer can be used e.g. for preparing cosmetic or pharmaceutical compositions. The dendrimers have a good vitamin C load capacity and are biocompatible.Type: ApplicationFiled: January 21, 2009Publication date: January 27, 2011Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRSInventors: Didier Astruc, Jaime Ruiz Aranzaes, Élodie Boisselier
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Publication number: 20110008306Abstract: The present invention provides methods of treating creatine responsive states, such as a neurological disorder (i.e., Huntington's disease, Parkinson's disease, amyotrophic lateral sclerosis and creatine transporter defect) or a skin disorder, by administering a creatine-ligand compound, alone or in combination with an anti-inflammatory compound, to a subject.Type: ApplicationFiled: February 2, 2010Publication date: January 13, 2011Inventor: Belinda Tsao NIVAGGIOLI
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Publication number: 20100322881Abstract: The invention relates to compounds of formula (I), wherein R1, R2, R3, R4 have the meaning cited in the claims, to methods for the production thereof, agents containing said compounds and to their use for the functionalisation of matrices, in particular their use as skin and/or hair-binding UV filters.Type: ApplicationFiled: January 15, 2009Publication date: December 23, 2010Applicant: MERCK PATENT GESELLSCHAFTInventors: Thomas Rudolph, Philipp Buehle
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Patent number: 7851526Abstract: Polymers initiated with furanones and compositions containing such polymers are suitable for use in making textiles, medical devices, delivery agents, packaging materials, coatings for such items, and the like.Type: GrantFiled: May 14, 2007Date of Patent: December 14, 2010Assignee: Tyco Healthcare Group LPInventors: Joshua B. Stopek, Joseph Hotter, Steve Tsai
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Patent number: 7846903Abstract: A cubic liquid crystal composition comprising at least one amphiphilic compound having the following general formula (1) and having an IV/OV value of 0.65 to 0.95, and water or an aqueous medium: wherein R represents a hydrophilic group; X and Y each independently represent a hydrogen atom or together form an oxygen atom; n is an integer of 0 to 4; and m is an integer of 0 to 3.Type: GrantFiled: October 19, 2005Date of Patent: December 7, 2010Assignees: National Institute of Advanced Industrial Science and Technology, Kuraray Co., Ltd., Cytopathfinder, Inc.Inventors: Masakatsu Hato, Yoshiji Fujita, Toshitaka Ota, Masahisa Tanomura, Manzo Shiono
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Publication number: 20100297261Abstract: A food product comprising a source of at least one metal ion selected from Fe and Cu ions and an ascorbic acid derivative substituted in the 2-position, wherein the molar ratio of the metal ion or metal ions in the source of metal ions to the ascorbic acid derivative is from 1:0.5 to 1:15.Type: ApplicationFiled: July 18, 2006Publication date: November 25, 2010Inventors: Salomon Leendert Abrahamse, van Amelsvoort Netherlands Johannes, van Buuren Nicodemus M. Bernardus, Duchateau Servaac M.J.E. Gustaaf
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Patent number: 7838690Abstract: The present invention relates to a method for preparing 3-O-substituted ascorbic acid derivatives represented by formula 1, in which 5,6-O-isopropylidene ascorbic acid is reacted with a halide in an organic solvent in the presence of the anion exchange resin absorbed with multi-iodine anions and then deprotected. The method of the present invention has an advantage of providing a target compound with high purity and high yield by finishing the reaction within a short period of time at room temperature.Type: GrantFiled: December 7, 2006Date of Patent: November 23, 2010Assignee: Cosmol Co. LtdInventors: Sung-Ryoung Park, Geon-Min Lee
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Publication number: 20100217017Abstract: The invention relates to a process for the catalytic conversion of a carbohydrate, an alcohol, an aldehyde or a poly-hydroxy compound in the presence of a catalyst containing gold in a solvent.Type: ApplicationFiled: June 5, 2008Publication date: August 26, 2010Inventors: Werner Bonrath, Jocelyn Fischesser
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Publication number: 20100203135Abstract: Methods of forming soft connective tissue compositions such as skin equivalents, compositions made by the methods and their uses.Type: ApplicationFiled: March 14, 2006Publication date: August 12, 2010Inventors: Paul Kemp, David Shering, Andrew Shering, Penny Johnson, Damian Marshall
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Patent number: 7741496Abstract: The present invention discloses the ascorbic acid derivatives. The inventive molecules that combine with one or two hydrophilic headgroups connected by a hydrophobic spacer can increase skin penetration.Type: GrantFiled: September 3, 2009Date of Patent: June 22, 2010Assignee: Corum Inc.Inventors: Wei-Chuan Tsai, Chen-Yin Chen, Ming-Yi Chiu, Yi-Fan Ling, Nai-Hsuan Hsu
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Publication number: 20100113590Abstract: Disclosed is an ADAM inhibitor which enables to prevent or improve conditions caused by increase in ADAM activity. Specifically disclosed is an ascorbic acid derivative represented by the general formula (1) below or a salt thereof. [chemical formula 1] (1), wherein R represents a linear or branched alkyl group having 1 to 22 carbon atoms.Type: ApplicationFiled: December 27, 2007Publication date: May 6, 2010Applicant: Shiseido Company, Ltd.Inventors: Takuya Hiruma, Hirotada Fukunishi, Masaru Suetsugu, Yukiko Matsunaga, Satoshi Amano, Michio Shibata
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Patent number: 7696360Abstract: The invention relates to a method for the separation of ascorbic acid from a mixture containing ascorbic acid and 2-keto-L-gulonic acid in a polar, preferably aqueous solvent, by means of liquid/liquid extraction using an amide. The method preferably also comprises steps for the back-extraction of the ascorbic acid, recycling of the extraction solvent and/or the back extraction solvent and for isolation of the ascorbic acid from the back extraction solvent. The invention further relates to a method for the production of ascorbic acid from KGA and isolation of the ascorbic acid so produced.Type: GrantFiled: July 7, 2003Date of Patent: April 13, 2010Assignee: BASF AktiengesellschaftInventors: Gerd Kaibel, Martin Merger, Thomas Domschke, Petra Deckert, Friedrich Sauer
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Publication number: 20100056809Abstract: The present invention discloses the ascorbic acid derivatives. The inventive molecules that combine with one or two hydrophilic headgroups connected by a hydrophobic spacer can increase skin penetration.Type: ApplicationFiled: September 3, 2009Publication date: March 4, 2010Applicant: CORUM INC.Inventors: Wei-Chuan Tsai, Chen-Yin Chen, Ming-Yi Chiu, Yi-Fan Ling, Nai-Hsuan Hsu