Amino Nitrogen Attached To Aryl Ring Or Ring System By An Acyclic Carbon Or Chain Patents (Class 564/336)
  • Patent number: 4322530
    Abstract: A process for alkylating a polyamine by contacting, in a liquid media, a polyamine, an olefinic compound, carbon monoxide, and a hydrogen source in the presence of a catalytic amount of a rhodium atom containing compound selected from metallic rhodium, rhodium salts, rhodium oxides, rhodium carbonyls and ligands thereof at a temperature of from about 50.degree. C. to 250.degree. C. and at a pressure of from about 30 to about 300 atmospheres.
    Type: Grant
    Filed: February 22, 1980
    Date of Patent: March 30, 1982
    Assignee: W. R. Grace & Co.
    Inventor: Felek Jachimowicz
  • Patent number: 4317932
    Abstract: A process for forming amines by contacting, in a liquid media, an olefinic compound, carbon monoxide, water, and ammonia in the presence of a rhodium atom containing compound selected from metallic rhodium, rhodium salts, rhodium oxides, and rhodium carbonyls and ligands thereof at a temperature of from 50.degree. to 250.degree. C. and at a pressure of from about 10 to about 300 atmospheres.
    Type: Grant
    Filed: February 22, 1980
    Date of Patent: March 2, 1982
    Assignee: W. R. Grace & Co.
    Inventor: Felek Jachimowicz
  • Patent number: 4312861
    Abstract: Aralkylamines of the formula:R.sup.1 --CH.sub.2 --N(R.sup.3)--R.sup.2whereinR.sup.1 is a phenyl substituted by one of:(I) alkyls,(II) halo and(III) nitro;R.sup.2 is(IV) alkyl having from 4 to 10 carbon atoms, four of which are in one chain,(V) alkyl interrupted by an oxygen atom, i.e. an alkoxyalkyl or ether radical, or(VI) hydroxyalkyl wherein the alkyl is either (IV) or (V) and the hydroxy is the sole substituent;R.sup.3 is a hydrogen atom, alkyl having from 1 to 4 carbon atoms or such alkyl substituted by a dialkylphosphinyl group;a physiologically-compatible acid-addition salt thereof and a pharmaceutical composition containing such compound(s) as active ingredient(s) are valuable in view of the physiological activity, e.g. vasotonic, capillary sealing and antiarrhythmic, of the aralkylamines and their physiologically-compatible acid-addition salts.
    Type: Grant
    Filed: June 13, 1977
    Date of Patent: January 26, 1982
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Istvan Boksay, Alfons Soder, Volkher Bollmann, Rolf-Ortwin Weber
  • Patent number: 4257980
    Abstract: The present invention provides novel 2-decarboxy-2-aminomethyl-19,20-didehydro-13,14-dihydro-PG.sub.1 compounds, methods for their preparation and pharmacological use for the induction of prostaglandin-like effect.
    Type: Grant
    Filed: October 17, 1979
    Date of Patent: March 24, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Patent number: 4257979
    Abstract: The present invention provides novel 2-decarboxy-2-aminomethyl-19-hydroxy-19-methyl-PG compounds and methods for their preparation and pharmacological uses for the induction of prostaglandin-like effects.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: March 24, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Patent number: 4257984
    Abstract: The present invention relates to epoxy resin compositions and in particular to curing agents for such resin compositions. The present invention thus embraces monotertiarymonosecondarydiprimarytetramines and the precursor from which this amine is manufactured namely monotertiarymonosecondarydinitrilodiamines.
    Type: Grant
    Filed: April 4, 1977
    Date of Patent: March 24, 1981
    Assignee: Henkel Corporation
    Inventor: Stuart A. Harrison
  • Patent number: 4242355
    Abstract: Novel derivatives of 3-(aminoethyl)-phenols of the formula ##STR1## wherein A is a simple bond or alkylene of 1 to 6 carbon atoms and B is selected from the group consisting of aryl, diarylmethyl, cycloalkyl of 3 to 10 carbon atoms and heteroaryl with the proviso that B is not phenyl when A is ethylene and their non-toxic, pharmaceutically acceptable acid addition salts having a dopaminergic activity and their preparation.
    Type: Grant
    Filed: September 17, 1979
    Date of Patent: December 30, 1980
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Daniel Frechet, Claude Dumont