Polyphenols Patents (Class 568/717)
  • Patent number: 11239428
    Abstract: An organic compound containing boron and uses thereof, an organic mixture, and an organic electronic device, the structure of said organic compound containing boron being as shown in formula (1). The substituents in formula (I) have the same definitions as in the description.
    Type: Grant
    Filed: November 23, 2017
    Date of Patent: February 1, 2022
    Assignee: Guangzhou Chinaray Optoelectronic Materials Ltd.
    Inventors: Hong Huang, Junyou Pan
  • Patent number: 10851201
    Abstract: The invention relates to a curing agent for thermosetting epoxy resins comprising (a) at least one aromatic amine containing at least two amino groups, and (b) at least one clathrate compound obtained by reacting a tetrakisphenol of the formula (1), or a 9,9-Bis(4-hydroxyphenyl)fluorene of formula (2), as the host molecule, and an imidazole or an imidazolium derivative as the guest molecule, wherein the substituents are as defined in the description, and n is the number 0, 1, 2 or 3, which can advantageously be used for the curing of epoxy resins. In addition, the invention also relates to a process for the preparation of a cured article, a process for the preparation of insulation systems for electrical engineering and a cured article obtained by the processes.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: December 1, 2020
    Assignee: HUNTSMAN INTERNATIONAL LLC
    Inventors: Christian Beisele, Sophie Colliard, Catherine Schoenenberger
  • Patent number: 10155969
    Abstract: The present invention relates to a process for preparing a compound having the formula (I), said process comprising the following steps: a) the addition of an oxygen source into a solution of a compound of formula (II), in a water-miscible solvent, b) the addition of a laccase in the solution obtained after step a); and c) the possible recovering of the compound of formula (I) thus obtained.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: December 18, 2018
    Assignees: UNIVERSITE DE BORDEAUX, INSTITUTE POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)
    Inventors: Stéphane Grelier, Henri Cramail, Audrey Llevot, Stéphane Carlotti, Etienne Grau
  • Publication number: 20150045560
    Abstract: Described herein are heterocyclic organic compounds of following formulae: More specifically, described herein are fused heterocyclic naphthalene compounds, polymers based on fused heterocyclic naphthalene compounds, methods for making these compounds, and uses thereof. The compounds described have improved polymerization and stability properties that allow for improved material processibility for use as organic semiconductors (OSCs).
    Type: Application
    Filed: March 28, 2013
    Publication date: February 12, 2015
    Inventors: Mingqian He, Jieyu Hu, Weijun Niu, Adama Tandia
  • Patent number: 8889919
    Abstract: A cyclic compound represented by formula (1): wherein L, R1, R?, and m are as defined in the specification. The cyclic compound of formula (1) is highly soluble to a safety solvent, highly sensitive, and capable of forming resist patterns with good profile. Therefore, the cyclic compound is useful as a component of a radiation-sensitive composition.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: November 18, 2014
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Masatoshi Echigo, Hiromi Hayashi
  • Publication number: 20140316098
    Abstract: In a process for producing phenol, a composition comprising an alkylaromatic compound is contacted with an oxygen-containing stream in the presence of an oxidation catalyst comprising a cyclic imide under oxidation conditions effective to oxidize 15 wt % or less of the alkylaromatic compound based upon the total weight of the composition and produce an oxidation product comprising unreacted alkylaromatic compound and alkylaromatic hydroperoxide in a molar ratio of 6:1 to 100:1. Thereafter, at least a portion of the oxidation product is contacted with an acidic molecular sieve catalyst under cleavage conditions effective to convert at least a portion of the alkylaromatic hydroperoxide into phenol and cyclohexanone.
    Type: Application
    Filed: December 15, 2011
    Publication date: October 23, 2014
    Applicant: ExxonMobil chemical Patents Inc.
    Inventors: Kun Wang, Roberto Garcia, Jihad M. Dakka, Gabor Kiss
  • Patent number: 8846013
    Abstract: The present invention relates to compositions comprising 1-hydroxyl 3,5-bis(4?hydroxyl styryl)benzene or a cosmetically acceptable salt thereof, and methods of treating human skin and signs of skin aging using said compositions.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: September 30, 2014
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Simarna Kaur, Michael D. Southall, Robert A. Zivin
  • Patent number: 8829247
    Abstract: This invention addresses problems to provide a cyclic compound having a high solubility in safety solvents and a high sensitivity and being good in the shape of the resulting resist pattern, a method of producing the same, a radiation sensitive composition comprising the same, and a method of forming a resist pattern using the radiation sensitive composition. As means for solving the problem, there are provided a cyclic compound having a specific structure, a radiation sensitive composition comprising the compound, and a method of forming a resist pattern using the composition.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: September 9, 2014
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Hiromi Hayashi, Masatoshi Echigo, Dai Oguro
  • Patent number: 8816135
    Abstract: A trisphenol compound is expressed by formula (1), wherein R represents an alkyl group or alkoxyl group with 1 to 8 carbon atoms, phenyl group or hydroxyl group; R1 represents an alkyl group or alkoxyl group with 1 to 8 carbon atoms, or phenyl group; R2 represents an alkyl group or alkoxyl group with 1 to 8 carbon atoms; R3 represents a hydrogen atom or alkyl group with 1 to 8 carbon atoms; a represents 0, 1, 2, or 3; b represents 1 or 2; and c and d represent 0, 1, 2, 3, or 4; where the sum of b and c is 5 or less; R's may be either the same or different when a is 2 or more; R1's may be either the same or different when c is 2 or more; and R2's may be either the same or different when d is 2 or more.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: August 26, 2014
    Assignee: Honshu Chemical Industry Co., Ltd.
    Inventors: Akira Yoshitomo, Shihoko Nakano
  • Patent number: 8784853
    Abstract: Disclosed is the use of benzotropolone derivatives of formula (1), wherein R1, R2 and R7 independently from each other are hydrogen; C1-C3alkyl; or COR8; R3 is hydrogen; or COOR9 R4 is hydrogen; or C1-C3alkyl; R5 is hydrogen; hydroxy; C1-C3-alkoxy; or -0-(CO)—R10; R6 is hydrogen; C1-C3alkyl; or COR8; or R5 and R6 together may form a five or six membered ring; or R6 and R7 together form a five or six membered ring; and R8, R9, R10 independently of each other are C1-C30alkyl; for protecting body-care and household products from photolytic and oxidative degradation.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: July 22, 2014
    Assignee: BASF SE
    Inventors: Barbara Wagner, Oliver Reich, Alexander Mantler, Reinhold Öhrlein, Walter Fischer, Albert Schneider
  • Patent number: 8758731
    Abstract: The present invention relates to compositions comprising 1-hydroxyl 3,5-bis(4?hydroxyl styryl)benzene or cosmetically acceptable salt thereof, and methods of lightening skin using said compositions.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: June 24, 2014
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Chong Jin Loy, Samantha Tucker Samaras, Michael D. Southall
  • Publication number: 20140100341
    Abstract: Disclosed in the present invention is a fluorine-containing polymerizable compound of the general formula (1): where a and b each independently represent an integer of 0 to 2 and satisfy a relationship of a+b=2; c represents an integer of 0 to 3; d and e each independently represents an integer of 0 to 2 and satisfy a relationship of 1?d+e?4; and the moiety of the following formula may have a carbon atom replaced by a heteroatom (a nitrogen atom, an oxygen atom or a sulfur atom) and may have a hydrogen atom substituted with a substituent that may contain a nitrogen atom, an oxygen atom or a sulfur atom
    Type: Application
    Filed: May 29, 2012
    Publication date: April 10, 2014
    Applicant: Central Glass Company, Limited
    Inventors: Junya Nakatsuji, Makoto Matsuura, Kazuhiro Yamanaka
  • Publication number: 20130334461
    Abstract: Provided are a polymerizable liquid crystal composition, a coating material, a medium, and a polarizing device each produced using a polymerizable liquid crystal compound and a colorant and each capable of producing polarized light suitable for polarizing devices, and also a novel naphtholactam derivative, a novel coumarin derivative, a novel Nile Red derivative, and a novel anthracene derivative each suitable for use as the colorant. Specifically provided are a polymerizable liquid crystal composition containing (A) at least one liquid crystal compound having a polymerizable functional group, (B) at least one colorant, and (C) a polymerization initiator, and a novel naphtholactam derivative of formula (IV?), a novel coumarin derivative of formula (VI?), a novel Nile Red derivative of formula (VII?), and a novel anthracene derivative of formula (VIII?) each suitable for use as the colorant (B).
    Type: Application
    Filed: March 15, 2012
    Publication date: December 19, 2013
    Applicant: ADEKA CORPORATION
    Inventors: Yusuke Kubota, Masatomi Irisawa, Toru Yano, Ken Matsumoto
  • Publication number: 20130323372
    Abstract: The invention relates to a method for extracting molecules of interest from a plant matrix, the method including the following steps: electrically processing the plant matrix by means of pulsed power; diffusing the molecules of interest from the processed plant matrix in a hydroalcoholic solvent and/or a solvent including ethyl acetate; and recovering the molecules of interest that were diffused.
    Type: Application
    Filed: November 21, 2011
    Publication date: December 5, 2013
    Inventors: Philippe Msika, Caroline Baudouin, Franck Menu
  • Publication number: 20120238638
    Abstract: This invention pertains to a method of modifying biocides obtained from biological sources, namely polyphenols. The modified biocide may have protective groups to reduce or prevent the oxidation of these phenols. The protective groups may also control the rate of hydrolyzation with regards to biocide efficacy. This invention also includes a method wherein the modified biocide may be incorporated and stabilized into a substrate like plastic.
    Type: Application
    Filed: March 19, 2012
    Publication date: September 20, 2012
    Inventor: Jorma Antero Virtanen
  • Publication number: 20120156692
    Abstract: The present invention provides a method for selecting a marker for diagnosis of the nutritional status capable of reflecting the status of a particular nutrient in a plant without being influenced by various stresses in environmental factors, etc., and a method for diagnosing the status of a particular nutrient in a plant using a marker for diagnosis of the nutritional status selected by the method. A metabolite quantitatively changed depending on only the amount of a particular nutrient in a plant is selected as a marker for diagnosis of the nutritional status reflecting the status of the nutrient in the plant.
    Type: Application
    Filed: May 26, 2010
    Publication date: June 21, 2012
    Applicant: OJI PAPER CO., LTD.
    Inventors: Shinya Sasaki, Shigeru Sato
  • Publication number: 20120121536
    Abstract: Glucose deprivation is an attractive strategy in cancer research and treatment. Cancer cells upregulate glucose uptake and metabolism for maintaining accelerated growth and proliferation rates. Specifically blocking these processes is likely to provide new insights to the role of glucose transport and metabolism in tumorigenesis, as well as in apoptosis. As solid tumors outgrow the surrounding vasculature, they encounter microenvironments with a limited supply of nutrients leading to a glucose deprived environment in some regions of the tumor. Cancer cells living in the glucose deprived environment undergo changes to prevent glucose deprivation-induced apoptosis. Knowing how cancer cells evade apoptosis induction is also likely to yield valuable information and knowledge of how to overcome the resistance to apoptosis induction in cancer cells.
    Type: Application
    Filed: March 24, 2011
    Publication date: May 17, 2012
    Applicant: OHIO UNIVERSITY
    Inventors: Xiaozhuo Chen, Stephen Bergmeier
  • Publication number: 20120052757
    Abstract: The present invention provides methods of designing molecularly imprinted polymers (MIPs) which have applications in extracting bioactive compounds from a range of bioprocessing feedstocks and wastes. The present invention is further directed to MIPs designed by the methods of the present invention.
    Type: Application
    Filed: January 29, 2010
    Publication date: March 1, 2012
    Applicant: MONASH UNIVERSITY
    Inventors: Milton T. W. Hearn, Steven Langford, Kellie Louise Tuck, Simon Harris, Reinhard Ingemar Boysen, Victoria Tamara Perchyonok, Basil Danylec, Lachlan Schwarz, Jamil Chowdhury
  • Patent number: 8110334
    Abstract: A radiation-sensitive composition containing a resist compound having a high sensitivity, a high resolution, a high etching resistance, and a low outgas which forms a resist pattern with a good shape is described. Further described is a method of forming a resist pattern using the radiation-sensitive composition. Still further described are a novel composition for forming a photoresist under coat film which is excellent in optical properties and etching resistance and contains substantially no sublimable substance and an under coat film formed by the composition.
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: February 7, 2012
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Masatoshi Echigo, Dai Oguro
  • Patent number: 7923587
    Abstract: The present invention relates to macromonomer compounds possessing antioxidant properties, antioxidant polymers comprising the antioxidant macromonomers as a recurring unit, and methods of inhibiting oxidation in a substance comprising contacting the substance with the antioxidant polymers. In one embodiment, substantially all of the recurring macromonomeric units of the antioxidant polymers comprise an antioxidant moiety. In another embodiment, all of the recurring macromonomer units of the antioxidant polymers comprise an antioxidant moiety. The method of the present invention, yields antioxidant polymers with substantially all of the recurring units comprising an antioxidant moiety. These antioxidant polymers have greater bulk antioxidative properties than previously known.
    Type: Grant
    Filed: May 28, 2008
    Date of Patent: April 12, 2011
    Assignee: Polnox Corporation
    Inventor: Ashok L. Cholli
  • Publication number: 20100305313
    Abstract: The present invention relates to a process for the extraction of plant ingredients, which comprises a) comminuting plant material b) adding a solvent to the comminuted plant material c) subjecting the mixture of comminuted plant material and solvent to an ultrahigh temperature treatment at 95-150° C. over a period of 5-300 seconds.
    Type: Application
    Filed: December 16, 2008
    Publication date: December 2, 2010
    Applicant: Bayer CropScience AG
    Inventors: Michael Baeuerlein, Joseph Miller
  • Publication number: 20100233672
    Abstract: Special extracts of grape berries and Goji berries can be prepared by exposing fruit juices or preparations to an insoluble binding resin which is then extracted with soluble polyvinylpyrollidone. Grape and Goji extracts made in this way can be used to inhibit or control platelet aggregation. Grape extract has exceptional antibacterial properties and can be used to control oral bacteria and to control MRSA (Methicillin-resistant Staphylococcus aureus). The combination of control of platelet aggregation and antibacterial properties exhibited by the grape-extract allows it to be used to significantly extend the life of isolated platelets. When added to solutions of isolated platelets, the grape extract prevents bacterial growth and prevents deterioration of the platelets through activation. This treatment extends the usable life of platelet concentrates to at least ten days. In addition, polyphenols can be used as a medicament for modulation of platelet activity in vitro.
    Type: Application
    Filed: November 6, 2008
    Publication date: September 16, 2010
    Applicant: Shanbrom Technologies, LLC
    Inventor: Edward Shanbrom
  • Patent number: 7763291
    Abstract: The objective of the present invention is to provide a tea polyphenol composition that has reduced bitterness and astringency while containing catechins with high purity. The present invention provides a tea polyphenol composition, (A) comprising 85% by weight to 95% by weight of catechins, (B) wherein the catechins contains epigallocatechin gallate and gallocatechin gallate at a ratio of 65% by weight to 80% by weight and (C) wherein the ratio given by (epigallocatechin gallate+gallocatechin gallate)/(epicatechin+catechin+epigallocatechin+gallocatechin+epicatechin gallate+catechin gallate) is from 2 to 4.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: July 27, 2010
    Assignee: Mitsui Norin Co., Ltd.
    Inventors: Yukihiko Hara, Ryota Seto
  • Patent number: 7749525
    Abstract: A composition-of-matter comprising a substance usable in producing packaging material and at least one compound selected from the group consisting of ar-turmerone, a sesquiterpene alcohol and a turmeric oleoresin solid residue.
    Type: Grant
    Filed: April 5, 2004
    Date of Patent: July 6, 2010
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center, Biopack Ltd.
    Inventors: Shlomo Navarro, Simcha Finkelman, Dov Zehavi, Refael Dias, Sam Angel, Fadel Mansur, Miriam Rindner
  • Patent number: 7745670
    Abstract: Novel molecules based upon hybridization of curcumin and hydroxystilbenes, such as resveratrol. It is believed that these novel molecules will have special application in treating Alzheimer's Disease.
    Type: Grant
    Filed: December 24, 2008
    Date of Patent: June 29, 2010
    Assignee: Codman & Shurtleff, Inc.
    Inventor: Thomas M. DiMauro
  • Publication number: 20100158885
    Abstract: Methods of and compositions for producing and using plant-based materials are provided. The methods include using biopolymers or their synthetic equivalents combined with a stable source of reactive oxygen species that when applied to or combined with a separate source of oxido-reducing enzyme or catalyst will cause the formation of an activated biopolymer with increased protein binding affinity and microbial control activities.
    Type: Application
    Filed: March 1, 2010
    Publication date: June 24, 2010
    Applicant: METAACTIV, INC.
    Inventors: Alexander L. Huang, Gin Wu
  • Publication number: 20100022788
    Abstract: The present invention relates to a new method of extraction of solid compounds by microwaves and to the apparatus used in said method.
    Type: Application
    Filed: January 21, 2008
    Publication date: January 28, 2010
    Applicants: Milstone S.r.l., Unversite D'Avignon ET Des Pays De Vaucluse
    Inventors: Chemat Farid, Tomao Valerie, Franco Visinoni
  • Publication number: 20100016347
    Abstract: The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.
    Type: Application
    Filed: July 21, 2009
    Publication date: January 21, 2010
    Applicant: Unigen Pharmaceuticals, Inc.
    Inventors: Sandip K. Nandy, Jiyun Liu, Alexandre Mikhailovitch Nesterov, Carmen Hertel, Abeysinghe A. Padmapriya
  • Publication number: 20100004333
    Abstract: The present invention relates to compounds and methods for the treatment of cardiovascular diseases and disorders. Compounds according to the present invention may comprise an optionally substituted phenyl ring linked to an aromatic or alkyl group by a spacer, wherein the spacer comprises two groups selected from selenium, sulfur, S(O) and S(O)2 and may further optionally comprise an alkylene, alkenylene, cycloalkylene or arylene moiety between the respective selenium, sulfur, S(O) and S(O)2 groups.
    Type: Application
    Filed: December 16, 2005
    Publication date: January 7, 2010
    Inventor: Roland O. Stocker
  • Publication number: 20090326018
    Abstract: The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity. Formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined in the specification, and wherein either the bond between the C1 and C2 carbon atoms is a double bond or the bond between the C2 and C3 carbon atoms is a double bond, R2 being absent when the bond between the C1 and C2 carbon atoms is a double bond.
    Type: Application
    Filed: October 12, 2007
    Publication date: December 31, 2009
    Inventors: Henrik Jernstedt, Lars Krüger, Patrik Rhönnstad, Daniel Nöteberg
  • Patent number: 7622613
    Abstract: The present invention relates to a thiol compound represented by formula (1): wherein R1, R2 and n have the same meanings as in the specification, method for producing the compound, and to a photosensitive composition and a black matrix resist composition using the same which have high sensitivity and excellent property of retaining a line width in fine line patterns at the time of alkaline development, that is, being excellent in development latitude.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: November 24, 2009
    Assignee: Showa Denko K.K.
    Inventors: Hirotoshi Kamata, Mina Onishi, Katsumi Murofushi
  • Publication number: 20090215925
    Abstract: The invention relates to a dispersion or solution of a polymer in water, organic solvents or mixtures thereof. The invention is characterised in that the polymer contains at least 0.001 mols of 3,4 dihydroxyphenyl groups (calculated at 109 g/mol) for 100 g polymer.
    Type: Application
    Filed: January 18, 2005
    Publication date: August 27, 2009
    Applicant: BASF Aktiengesellschaft
    Inventors: Dieter Urban, Reinhold Schwalm, Stefan Kirsch, Kai Michael Exner, Alexander Centner
  • Publication number: 20090137848
    Abstract: An improved process for the manufacture of a polyphenol compound such as bisphenol-A by introducing into a reaction zone a phenolic compound reactant, a carbonyl compound reactant, and a catalyst promoter comprising bismethylthiopropane added to the reaction system in certain specific locations, and reacting the ingredients within the reaction zone in the presence of an acid catalyst.
    Type: Application
    Filed: May 4, 2006
    Publication date: May 28, 2009
    Applicant: BADGER LICENSING LLC
    Inventors: Stephen W. Fetsko, Steven D. Evitt
  • Publication number: 20090036542
    Abstract: The present invention provides compounds represented by formula (1) shown below: (wherein R1, R2, R3, R4, and R5 are each individually selected from among a hydrogen atom, methyl group, acetyl group, hydroxyl group, and alkoxy group; and X represents an alkylene group or alkenylene group); and compounds represented by formula (2) shown below: (wherein R6, R7, R8, R9, and R10 are each individually selected from among a hydrogen atom, alkyl group, acetyl group, hydroxyl group, and alkoxy group; A represents an oxygen atom or NH, and m is 0 or 1; and Y represents an alkylene group or alkenylene group, and Z represents a hydrogen atom or hydroxyl group). The compounds of the present invention are useful for preventing or treating brain dysfunctions, motor dysfunctions, or urinary dysfunctions caused by the degeneration and/or loss of the central nervous system or peripheral nervous system cells.
    Type: Application
    Filed: February 23, 2006
    Publication date: February 5, 2009
    Inventors: Bang Luu, Dominique Bagnard, Mazen Hanbali, Masashi Yamada, Hiroto Suzuki
  • Patent number: 7473549
    Abstract: The present invention provides a target recognizing element wherein a receptor is fixed to an inclusion complex containing a mediator. The target recognizing element includes a first host molecule having hydrophilic groups and an inclusion site, a second host molecule having hydrophilic groups and an inclusion site, a receptor which is bonded to the hydrophilic groups of the second host molecule and which reacts with the target, and a guest molecule which is included by the inclusion site of the first host molecule and the inclusion site of the second host molecule and which transfers an electric charge generated by the reaction between the target and the receptor.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: January 6, 2009
    Assignee: Rohm Co., Ltd.
    Inventors: Atsushi Ikeda, Jun-ichi Kikuchi, Haruo Kotani, Yoko Hayashi, Takaaki Shimasaki
  • Publication number: 20080300298
    Abstract: The present invention provides novel honokiol derivatives, as well as pharmaceutical compositions containing the honokiol derivatives. These compounds and pharmaceutical compositions can be used in the prevention and/or treatment of cancer. In particular, honokiol derivatives, pharmaceutical compositions comprising the derivatives, and methods for their use in the treatment of myeloma are provided.
    Type: Application
    Filed: February 23, 2006
    Publication date: December 4, 2008
    Inventors: Jack L. Arbiser, Frank Amblard
  • Publication number: 20080286393
    Abstract: An improved method for concentrating/enriching the polyphenolic contents from the dried, unripe fruit rinds of Terminalia belerica is disclosed. The present invention also discloses a light colored, enriched/concentrated (85%-100%) polyphenolic extract from the dried, unripe fruit rinds of Terminalia belerica which, by virtue of its excellent skin lightening, anti-aging, anti-inflammatory, anti-oxidant, UV protective, anti-microbial, sebum control, anti-acne and safety properties shows tremendous nutra-cosmetic potential as topical/oral “skin care” and “hair care” formulations. Additionally, the oral nutra-cosmetic formulations containing the light colored, enriched/concentrated (85%-100%), polyphenolic extract from the dried, unripe fruit rinds of Terminalia belerica, in view of their excellent 5-alpha-reductase activity, provide a natural therapeutic alternative to the problems of Benign prostatic hyperplasia (BPH), prostate cancer, and prostatitis.
    Type: Application
    Filed: May 18, 2007
    Publication date: November 20, 2008
    Inventor: Muhammed Majeed
  • Publication number: 20080200734
    Abstract: Processes for producing bisphenols (e.g., bisphenol A (BPA)) having a purity greater than 99.7% are described, such processes including reacting a phenol and acetone in the presence of an acidic catalyst to form a product mixture comprising a bisphenol; removing at least a portion of the bisphenol from the product mixture in the form of a bisphenol/phenol adduct by crystallization, filtration and washing to provide bisphenol/phenol adduct crystals; and removing at least a portion of the phenol from the bisphenol/phenol adduct crystals to provide the bisphenol having a purity of more than 99.7%; wherein the crystallization comprises continuous suspension crystallization and is carried out in at least three crystallization devices arranged such that the product mixture is first cooled in a first stage of the crystallization to a temperature of 50 to 70° C.
    Type: Application
    Filed: January 9, 2008
    Publication date: August 21, 2008
    Applicant: Bayer Material Science AG
    Inventors: Christian Munnich, Ulrich Blaschke, Rob Eek, Michael Prein, Raymond Audenaert, Gert Tytgat
  • Patent number: 7414160
    Abstract: A process produces an aromatic compound by bringing an aromatic compound (B) into contact with molecular oxygen (C) in the presence of a catalyst (A) comprising at least one of (A1) a heteropolyacid and/or a salt thereof, and (A2) a mixture of oxoacids and/or salts thereof containing, as a whole, one of P and Si and at least one selected from V, Mo and W to thereby yield another aromatic compound (G) than the aromatic compound (B). The process can produce, for example, a corresponding aromatic hydroxy compound (G1) by allowing the aromatic compound (B) to react with the molecular oxygen (C) further in the presence of a reducing agent (D).
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: August 19, 2008
    Assignee: Daicel Chemical Industries, Ltd.
    Inventors: Yasutaka Ishii, Tatsuya Nakano
  • Patent number: 7321050
    Abstract: The present invention provides novel diphenyl ethene compounds and pharmaceutically-acceptable salts thereof. Also provided are methods for making the compounds of the invention as well as methods for the use thereof in the treatment of immune, inflammatory, and auto-immune diseases.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: January 22, 2008
    Assignee: Welichem Biotech Inc.
    Inventors: Genhui Chen, John M. Webster, Jianxiong Li, Kaji Hu, Wei Liu, Jiang Zhu
  • Patent number: 7312368
    Abstract: A method for the selective reduction of an aromatic compound. The present invention provides a method for pre-venting the reduction of at least one halogen substituted aromatic ring of an aromatic compound, while allowing the reduction of at least one functional group on the aromatic compound. In the present invention at least one hydroxyl group is placed on the at least one halogen substituted aromatic ring to be protected from reduction. The aromatic compound is then reacted with at least one alkali metal in at least one nitrogen containing base and at least one alcohol at a ratio of the alcohol to the nitrogen containing base at which the aromatic ring with the hydroxyl group is protected from reduction, while the desired functional group is reduced.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: December 25, 2007
    Assignee: Mallinckrodt Inc.
    Inventors: Peter Xianqi Wang, Frank W. Moser
  • Patent number: 7230141
    Abstract: A process for preparing toluene derivatives of the formula I, where R1, R2 and R3 independently of one another are hydrogen, halogen, C1–C6-alkyl, hydroxyl or C1–C6-alkoxy, by hydrogenating benzaldehydes and/or benzyl alcohols of the formula II, with hydrogen in the presence of a catalyst, which is described in more detail in the description.
    Type: Grant
    Filed: January 20, 2003
    Date of Patent: June 12, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Nils Bottke, Rolf-Hartmuth Fischer, Thomas Nöbel, Markus Rösch
  • Patent number: 7161000
    Abstract: Provided is a method for producing a phenol condensate by oxidative condensation of a phenol compound not having a substituted group on at least one ortho-position, in the presence of a specific complex (II) and oxygen, wherein a condensate coupled at para-position of the phenol can be produced in an excellent yield, L-M (X)n??(II) wherein L represents a ligand having 2 to 4 nitrogen atoms as donor atoms, M represents copper ion, nickel ion, cobalt ion, iron ion, manganese ion, chromium ion or vanadyl ion, X represents a counter ion, n is a number of Xs.
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: January 9, 2007
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Hideyuki Higashimura, Eiichi Kotake, Masaaki Kubota, Shiro Kobayashi
  • Patent number: 7125951
    Abstract: The invention relates to bisphenol monomers containing one or more biaryl units and related polymers, derivatives and resins thereof and more particularly to Bisphenol monomers containing two biaryl units separated by a spacer group X, and to bisphenol monomers containing a biaryl unit and an aryl unit separated by a spacer group X, and to polymers, derivatives, resins and related products prepared therefrom.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: October 24, 2006
    Assignee: South Dakota School of Mines and Technology
    Inventors: David A. Boyles, John T. Bendler
  • Patent number: 7126031
    Abstract: New ligands and compositions with bridged bis-aromatic ligands are disclosed that catalyze the polymerization of monomers into polymers. These catalysts with metal centers have high performance characteristics, including higher comonomer incorporation into ethylene/olefin copolymers, where such olefins are for example, 1-octene, propylene or styrene. The catalysts also polymerize propylene into isotactic polypropylene.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: October 24, 2006
    Assignee: Symyx Technologies, Inc.
    Inventors: Thomas R. Boussie, Oliver Brümmer, Gary M. Diamond, Christopher Goh, Anne M. LaPointe, Margaret K. Leclerc, James A. W. Shoemaker
  • Patent number: 7087799
    Abstract: An object of the present invention is to provide a material which resolves the drawbacks associated with polyimide polymers, and yet retains the advantages offered by conventional polyimide polymers. An amino group containing phenol derivative of the present invention is represented by a general formula (1) show below, and the present invention also provides a polyimide precursor produced using such an amino group containing phenol derivative. (wherein, R1, R2 and R3, which may be the same or different, each represent an alkyl group of 1 to 9 carbon atoms, an alkoxy group of 1 to 10 carbon atoms, a COOR group (in which R represents an alkyl group of 1 to 6 carbon atoms) or a hydrogen atom; R4 and R5, which may be the same or different, each represent an alkyl group of 1 to 9 carbon atoms or a hydrogen atom; X represents —O—, —S—, —SO2—, —C(CH3)2—, —CH2—, —C(CH3)(C2H5)—, or —C(CF3)2—; and n represents an integer of 1 or greater).
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: August 8, 2006
    Assignee: Gun Ei Chemical Industry Co., Ltd.
    Inventors: Takeshi Tsuihiji, Michiyasu Yamazaki
  • Patent number: 7045664
    Abstract: In a process for producing bisphenol A, an adduct of bisphenol A with phenol is promptly recovered in highly purity and high efficiency from a reaction mother liquor in the case of singling out bisphenol A from a reaction product. An adduct layer of bisphenol A with phenol is formed by crystallizing an adduct of bisphenol A with phenol from a solution of bisphenol A in phenol to form a slurry, the bisphenol A being produced by reacting phenol and acetone in the presence of an acid catalyst, subjecting the resultant slurry to a solid-liquid separation treatment, and thereafter removing the phenol from solid components, characterized by pouring onto a filter, a slurry solution of bisphenol A in phenol, the slurry solution containing in a crystalline state, an adduct of bisphenol A having an average particle size in the range of 0.05 to 1 mm with phenol, and filtering the slurry solution under reduced pressure in an atmosphere of an inert gas stream at 30 to 80° C.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: May 16, 2006
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventors: Kazuyuki Hirano, Norio Ogata
  • Patent number: 7019179
    Abstract: A process produces an aromatic compound by bringing an aromatic compound (B) into contact with molecular oxygen (C) in the presence of a catalyst (A) comprising at least one of (A1) a heteropolyacid and/or a salt thereof, and (A2) a mixture of oxoacids and/or salts thereof containing, as a whole, one of P and Si and at least one selected from V, Mo and W to thereby yield another aromatic compound (G) than the aromatic compound (B). The process can produce, for example, a corresponding aromatic hydroxy compound (G1) by allowing the aromatic compound (B) to react with the molecular oxygen (C) further in the presence of a reducing agent (D).
    Type: Grant
    Filed: March 6, 2003
    Date of Patent: March 28, 2006
    Assignee: Daicel Chemical Industries, Ltd.
    Inventors: Yasutaka Ishii, Tatsuya Nakano
  • Patent number: 6960641
    Abstract: A method of preparing block copolymers by solid state polymerization is described. A mixture of a partially crystalline polycarbonate having activated terminal aryloxy groups, for example terminal methyl salicyl groups, when heated together with an oligomeric polyester having reactive terminal hydroxy groups under solid state polymerization conditions affords block copolymers. The activated terminal aryloxy groups play a key role in preserving the block lengths of the starting materials. A control sample in which the partially crystalline polycarbonate lacks activated terminal aryloxy groups, for example polycarbonates substituted by phenol, affords a much lower molecular weight, more highly randomized copolymer product. The product block copolymers are useful as “weatherable” plastic materials.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: November 1, 2005
    Assignee: General Electric Company
    Inventors: Gregory Allen O'Neil, James Day, Daniel Joseph Brunelle, Joseph Anthony Suriano, Patrick Joseph McCloskey, Paul Michael Smigelski, Jr.
  • Patent number: 6960665
    Abstract: The present invention concerns a process for arylating or vinylating or alkynating a nucleophilic compound. More particularly, the invention concerns arylating nitrogent-containing organic derivatives. The arylating or vinylating or alkynating process of the invention consists of reacting a nucleophilic compound with a compound carrying a leaving group and is characterized in that the reaction is carried out in the presence of an effective quantity of a catalyst based on a metallic element M selected from groups (VIII), (Ib) and (IIb) of the periodic table and at least one at least bidentate ligand comprising at least two chelating atoms, namely at least one oxygen atom and at least one nitrogen atom.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: November 1, 2005
    Assignee: Rhodia Chimie
    Inventors: Pascal Philippe Cellier, Henri-Jean Cristau, Jean-Francis Spindler, Marc Taillefer