Nuclear Radiation (e.g., Radioactive Emission, Etc.) Patents (Class 600/436)
  • Patent number: 11112454
    Abstract: Described herein are antenna-coupled radio frequency (RF) probes with replaceable tips. In the described embodiments, test signals are coupled onto a probe tip wafer via an on-tip antenna, thus the probe tip is decoupled from the probe body. This allows for separate fabrication of the probe body and the probe tip. As such, the probe tip can be made available as a “commodity” and the user can simply replace a worn-out or damaged probe tip, providing significant savings in per-unit cost and operation cost of the new contact probes. The decoupling of probe tip and probe body allows for manual replacement of probe tip without the need for extremely accurate alignment which is typically required in extremely high frequency probes. Manual replacement of the tips is only possible due to the much less stringent alignment requirements afforded by the antenna coupling from the probe body to the probe tip.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: September 7, 2021
    Assignee: Ohio State Innovation Foundation
    Inventor: Kubilay Sertel
  • Patent number: 11092698
    Abstract: A radiation imaging system comprises a plurality of imaging apparatuses configured to generate images based on radiation emitted from a radiation generator, and a control apparatus configured to communicate with the plurality of imaging apparatuses. Each of the plurality of imaging apparatuses generates imaging information with a smaller data size than an image obtained by an imaging operation based on the image. The control apparatus acquires the imaging information from each of the plurality of imaging apparatuses, and selects, from the plurality of imaging apparatuses based on the imaging information, an imaging apparatus from which an image obtained by an imaging operation is acquired.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: August 17, 2021
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Hikaru Tanaka, Yuichi Nishii, Kenta Endoh, Tomohiro Kawanishi
  • Patent number: 11076943
    Abstract: A surgical device is provided. The surgical device includes a housing adapted for mounting on a finger of a user; and at least one guide tube attached along a length of the housing. The guide tube is configured for guiding a tissue repair implant from a proximal opening to a distal opening thereof.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: August 3, 2021
    Assignee: FEMSELECT LTD
    Inventors: Boaz Harari, Guy Ohad
  • Patent number: 11033244
    Abstract: The present invention relates to an in vivo radiation amount measuring instrument. An in vivo radiation amount measuring instrument according to the present invention comprises: a main body elongated along an in vivo inserting direction and capable of supplying a fluid; an expanding part having at least a portion thereof fixed or connected to the main body and capable of being expanded and contracted by means of the outflow/inflow of the fluid; and a radiation measuring part disposed on the expanding part and measuring the amount of surface radiation distribution on in vivo tissue which the expanding part contacts by expanding.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 15, 2021
    Assignee: NATIONAL CANCER CENTER
    Inventors: Young Kyung Lim, Eun Hee Jeang, Ui-Jung Hwang, Kwan Ho Cho, Se Byeong Lee, Dongho Shin, Jeonghoon Park, Dae Yong Kim, Joo-Young Kim, Tae Hyun Kim, Sun Young Kim, Kwanghyun Jo, Ki Mun Kang, Hojin Jeong
  • Patent number: 10962662
    Abstract: A method and apparatus are provided for positron emission imaging to calibrate timing of a pixelated gamma detector using multi-channel events. The apparatus can include processing circuitry configured to obtain calibration data representing a time and a position at which gamma rays are detected at a plurality of detector elements, and determine which gamma-ray detections of the calibration data correspond to multi-channel detections in which energy of a respective gamma ray is shared and detected by two or more of the plurality of detector elements. Additionally, the processing circuitry can be configured to determine a timing calibration of the plurality of detector elements by optimizing an objective representing agreement between time data of the multi-channel detections in the calibration data and the timing calibration.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: March 30, 2021
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Yi Qiang, Xiaoli Li, Kent C. Burr
  • Patent number: 10949971
    Abstract: A method include obtaining at least one first PET image of a subject acquired by a PET scanner and at least one first MR image of the subject acquired by an MR scanner. The method may also include obtaining a target neural network model. The target neural network model may provide a mapping relationship between PET images, MR images, and corresponding attenuation correction data, and output attenuation correction data associated with a specific PET image of the PET images. The method may further include generating first attenuation correction data corresponding to the subject using the target neural network model based on the at least one first PET image and the at least one first MR image of the subject, and determining a target PET image of the subject based on the first attenuation correction data corresponding to the subject.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: March 16, 2021
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Lingzhi Hu, Tuoyu Cao, Gang Yang, Yang Lyu
  • Patent number: 10925562
    Abstract: A system for imaging includes a gantry movable relative to a subject. A source is configured to emit radiation during an imaging procedure. A detector is configured to receive attenuated radiation from the source during an imaging procedure, at least one of the source and the detector movably secured to the gantry by an adjustable joint. An imaging controller is operably connected to at least the gantry and to the adjustable joint, wherein the gantry controller receives a priori patient information and imaging system geometry information, the imaging controller determines an imaging geometry and operates the gantry and the adjustable joint to vary a source to image-receptor distance (SID) according to the imaging geometry.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: February 23, 2021
    Assignee: General Electric Company
    Inventors: Thomas Mc Carthy, Gregoire Avignon
  • Patent number: 10796465
    Abstract: A method for establishing and/or reducing artifacts that arise when reconstructing (R) an MPI overall image data record from MPI signal data and an appended system matrix (SMapp(r,f)), wherein the appended system matrix (SMapp(r,f)) includes system matrices of different particle classes (P1, P2). The method includes setting a selection region (cvn(r)) of a reconstructed MPI overall image data record (cn(r)), producing virtual signal data (sn(f)) by inverse transformation of the selection region, reconstructing a virtual overall image data record (c?vn(r)) from the virtual signal data and the appended system matrix, setting an artifact region (cartifact_n(r)) within the reconstructed virtual overall image data record so that the artifact region has only voxels lying outside of the selection region, and assigning the image data present in the artifact region as artifact image data (cartifact_n(r)). This permits ghost artifacts to be corrected.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: October 6, 2020
    Assignee: BRUKER BIOSPIN MRI GMBH
    Inventors: Jochen Franke, Michael Herbst
  • Patent number: 10722171
    Abstract: A device for measuring a plurality of parameters of a patient subject to a treatment with radiopharmaceuticals includes a main body constrained to the patient's body in such a way that the measurement device is of wearable type. The device includes a plurality of measurement modules, for example a first module and a second module, each of which is equipped with a respective sensor, configured to measure a predetermined parameter of the patient. The device is also equipped with a microprocessor configured to process a plurality of data measured by the plurality of sensors, obtaining a plurality of processed data. Furthermore, a transmission means is provided of wireless type arranged to send via wireless communication the data processed by the microprocessor to a remote control unit.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: July 28, 2020
    Assignee: WINMEDICAL S.R.L.
    Inventors: Pietro Valdastri, Ferdinando De Negri
  • Patent number: 10566091
    Abstract: Exemplified method and system facilitates monitoring and/or evaluation of disease or physiological state using mathematical analysis and machine learning analysis of a biopotential signal collected from a single electrode. The exemplified method and system creates, from data of a singularly measured biopotential signal, via a mathematical operation (i.e., via numeric fractional derivative calculation of the signal in the frequency domain), one or more mathematically-derived biopotential signals (e.g., virtual biopotential signals) that is used in combination with the measured biopotential signals to generate a multi-dimensional phase-space representation of the body (e.g., the heart). By mathematically modulating (e.g.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: February 18, 2020
    Assignee: Analytics For Life Inc.
    Inventors: Timothy Burton, Shyamlal Ramchandani, Sunny Gupta
  • Patent number: 10524745
    Abstract: A data acquisition device according to an embodiment includes processing circuitry. The processing circuitry is configured to compare the reference waveform of a signal, which is output from a detector that detects radiation, with the waveform of a detection signal based on the radiation, which enters the detector through the subject and which is detected by the detector. The processing circuitry is configured to estimate the information about the radiation, which enters the detector through the subject, in accordance with a comparison result.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: January 7, 2020
    Assignee: Canon Medical Systems Corporation
    Inventor: Emi Tamura
  • Patent number: 10492748
    Abstract: A radiation imaging apparatus includes a sensor unit in which a plurality of detecting elements each configured to detect emitted radiation are arranged, and a notification unit configured to make a notification by a sound. As the sound produced from the notification unit, a sound having a fundamental frequency which satisfies a condition determined based on the number of rows of a predetermined area of an image read out from the sensor unit and a readout frequency of signals of each row is used.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: December 3, 2019
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Hideki Nonaka, Taro Hiroike, Asato Kosuge
  • Patent number: 10478136
    Abstract: Aspects of the present disclosure disclose a system and method for delivering for administering radiation to a patient. The method may include associating the patient with one of a plurality of coded dosage zones wherein each of the plurality of coded dosage zones corresponds to one or more values of a physical characteristic. The method may further include correlating the one of the plurality of coded dosage zones to a dose of radiation and then applying the dose of radiation to the patient.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: November 19, 2019
    Inventor: Caleb Hernandez
  • Patent number: 10468241
    Abstract: Disclosed are various examples related to ion or particle spectrometry utilizing a monolithic collimator and energy analyzer. In one example, a particle selection device includes a single substrate including a curved channel energy analyzer section and a straight channel collimator section, wherein particles pass through the collimator section and enter the energy analyzer section of the substrate. The channel outlets in the collimator section are aligned with the channel inlets of the energy analyzer section. Electric and/or magnetic fields can be applied across the channels of the energy analyzer for ion or particle discrimination. A particle detector at the outlet of the energy analyzer section can provide indications of detected ions and/or particles.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: November 5, 2019
    Assignee: West Virginia University
    Inventors: Earl Scime, Amy M. Keesee, Matthew Phillip Dugas, Steven Brian Ellison, Joseph Christopher David Tersteeg, Drew B. Elliott
  • Patent number: 10295638
    Abstract: An image processing apparatus includes an image data acquisition unit, a development generating unit and a display unit. The image data acquisition unit acquires slice image data with regard to a heart of an object. The development generating unit obtains blood flow perfusion information with regard to a myocardial thickness direction based on the slice image data and generates development data according to a desired development format for displaying the blood flow perfusion information. The display unit displays the development data.
    Type: Grant
    Filed: June 24, 2008
    Date of Patent: May 21, 2019
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventor: Satoshi Sugiura
  • Patent number: 10231814
    Abstract: The disclosure provides an implantable medical device comprising a material capture element, which has a generally closed conical deployed shape and a narrow end disposed at or proximate the first end of the device. The material capture element includes a wide end facing the second end of the device, the material capture element having a zone of wider radial dimension which provides a first vessel contact site. A plurality of wire tethers are coupled to the wide end and extend to the second end. The wire tethers define a substantially open passageway for blood and provide a second vessel contact site. The first and second contact sites are spaced longitudinally from one another to provide stability. A first retrieval element is disposed at the first end and coupled to the narrow end, while a second retrieval element is disposed at the second end and coupled to the wire tethers.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: March 19, 2019
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Torben Peter Andersen, Jens Kold
  • Patent number: 10178979
    Abstract: A dual modality probe is disclosed having both a gamma probe sensor and an ultrasound sensor. A dual imaging system is provided having the probe and at least one external gamma imaging detector and a data acquisition computer system for collecting data simultaneously from the gamma probe sensor, the gamma imaging detector, and the ultrasound sensor of the probe. A method for evaluating a target organ of a patient utilizing the probe and imaging system, and performing a biopsy of the organ is disclosed.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: January 15, 2019
    Assignee: West Virginia University
    Inventors: Stanislaw Majewski, Gary Marano, Alexander Stolin, James Proffitt
  • Patent number: 10126438
    Abstract: Some aspects of the present disclosure relate to systems and methods for examining a subject. In one embodiment, a method includes polarizing nuclei of a radioactive substance such that the spins of the nuclei are oriented in a specific direction, to generate a polarized radioactive tracer with anisotropic gamma ray emission probability. The method also includes introducing the tracer into a subject. The method further includes applying radio frequency oscillating (RF) magnetic fields and/or spatially varying magnetic fields to the tracer that are configured to manipulate the orientation of the spins such as to manipulate the directional dependence of gamma ray emission from the tracer. The method further includes detecting gamma rays from the gamma ray emission, and obtaining, based on the detected gamma rays and properties associated with the anisotropic gamma ray emission, imaging data and/or spectroscopic data associated with the tracer in the subject.
    Type: Grant
    Filed: September 19, 2015
    Date of Patent: November 13, 2018
    Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Gordon D. Cates, Jr., G. Wilson Miller, Yuan Zheng, William A. Tobias
  • Patent number: 10052459
    Abstract: A catheter assembly includes a wire guide having a helical outer wire and a non-helical core wire slidable within the outer wire between an advanced position and a retracted position. The outer wire includes a steering tip having a medium stiffness and a bending bias, and the core wire includes a higher stiffness and a straightening bias. The assembly further includes a catheter slidable over the outer wire to a steering configuration. A distal catheter end includes a compliant lower stiffness, and is adjustable in the steering configuration between a straight shape and a curved shape.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: August 21, 2018
    Assignee: Cook Medical Technologies LLC
    Inventor: James R. Randolph
  • Patent number: 9939533
    Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: April 10, 2018
    Assignee: Lucerno Dynamics, LLC
    Inventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
  • Patent number: 9925940
    Abstract: A method and system may identify vehicle collisions in real-time or at least near real-time based on statistical data collected from previous vehicle collisions. A user's portable computing device may obtain sensor data from sensors in the portable computing device and compare the sensor data to a statistical model indicative of a vehicle collision, where the statistical model includes sensor data characteristics which correspond to the vehicle collision. The sensor data characteristics may include several threshold sample rate ranges at which another sensor data characteristic is measured and for each of the threshold sample rate ranges, a different threshold value for the other sensor data characteristic. If the portable computing device identifies a vehicle collision based on the comparison, notifications may be sent to emergency contacts and/or emergency personnel to provide assistance to the user.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: March 27, 2018
    Assignee: STATE FARM MUTUAL AUTOMOBILE INSURANCE COMPANY
    Inventors: Scott T. Christensen, David J. Dosher, Sunish Shreenarayan Menon, Susan M. Dunham
  • Patent number: 9921172
    Abstract: A nuclear level sensing gauge for measuring the level of product in a bin utilizes a plurality of scintillators arranged in a serial fashion. A source of nuclear radiation is positioned adjacent the bin, and the scintillators, which may be bundles of one or more scintillating fibers or scintillating crystals, are positioned in a serial fashion adjacent the bin opposite the source of nuclear radiation, such that nuclear radiation passing through the bin impinges upon the bundles. Light guides carry photons emitted by the scintillators—which are indicative of radiation passing through the bin—to a common photomultiplier tube. The tube is connected to electronics which convert counts of photons from the PMT into a measure of the level of radiation-absorbing product in the bin.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: March 20, 2018
    Assignee: Vega Americas, Inc.
    Inventors: Bonaventure Cahill, Thomas Niinemets
  • Patent number: 9895114
    Abstract: An imaging system includes a rotating gantry, a bed, plural nuclear medicine (NM) imaging detectors, and a processing unit. The rotating gantry has a bore. The NM detectors are disposed about the bore of the gantry. The NM detectors each have an in-plane field of view, and are configured to pivot about a corresponding axis with respect to the gantry to change the in-plane field of view. The processing unit is configured to acquire first NM imaging information at a first gantry rotational position, with the in-plane fields of view of the NM imaging detectors parallel to a predetermined direction; actuate the gantry to rotate to a second gantry rotational position; actuate the NM imaging detectors to pivot such that the in-plane fields of view are parallel to the predetermined direction; acquire additional NM imaging information at the second gantry rotational position; and reconstruct a planar image of the object.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: February 20, 2018
    Assignee: General Electric Company
    Inventors: Yaron Hefetz, Jonathan Sachs, Gil Kovalski, Avi Bar-Shalev
  • Patent number: 9820798
    Abstract: Targeted ablation of parathyroidal tissue is provided through hyperthermia adjuvant therapy. An in situ localization of parathyroidal tissue is obtained. A temperature-sensitive adjuvant is instilled into the parathyroidal tissue. Hyperthermia is therapeutically induced within the parathyroidal tissue. Heat-inducing energy is targeted into the parathyroidal tissue, which selectively includes the temperature-sensitive adjuvant. Application of the heat-inducing energy to the parathyroidal tissue is continued over a therapeutic range. In a further embodiment, the targeted ablation of the parathyroidal tissue is provided through hypothermia adjuvant therapy with the targeted use of cold-inducing energy.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: November 21, 2017
    Inventor: Alan N. Schwartz
  • Patent number: 9782078
    Abstract: The present invention relates to a system and a method for blood vessel imaging, detection, and marking and in particular, to such a system and method in which optical enhancers are utilized to increase the accuracy and quality of the process for detecting a blood vessel.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: October 10, 2017
    Inventor: Uzi Rahum
  • Patent number: 9743900
    Abstract: In some preferred embodiments, a medical imaging system with an integrated body monitoring device is disclosed which includes: a movable platform for supporting a patient during image acquisition; an image acquisition device for the acquisition of images of the patient upon the platform; a body monitoring device for the monitoring of a body function of the patient during image acquisition; the body monitoring device being adapted to transmit body function signals to the image acquisition device and the image acquisition device being adapted to effect image acquisition based on the signals received from the body monitoring device; wherein the body monitoring device is integrated with the image acquisition system. In the preferred embodiments, the medical imaging system is a nuclear medical imaging system and the body monitoring device is an ECG device.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: August 29, 2017
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventor: Ansgar Graw
  • Patent number: 9723988
    Abstract: An object of the present invention is to perform a more accurate and detailed diagnosis of a brain disease. A diagnosis server 10 of the brain disease diagnosis system 1 for diagnosing a brain disease of an examined person includes: an acquiring unit 11 for acquiring a brain image of the examined person so as to obtain an acquired image; a region setting unit 12 for setting a plurality of regions in the acquired image; an individual index value calculating unit 13 for calculating an individual index value based on a pixel value of the acquired image, in each of the plurality of regions; a whole index value calculating unit 14 for calculating a whole index value by weighting the individual index value of each of the plurality of regions; a diagnosis unit 15 for diagnosing the brain disease of the examined person based on the whole index value; and an output unit 16 for outputting information indicating a diagnosis outcome.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 8, 2017
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Akihiro Kakimoto, Yoshiyuki Shimizu, Tsuyoshi Kosugi, Hiroyuki Okada
  • Patent number: 9639952
    Abstract: An image processing apparatus includes a moving image acquiring unit that acquires a moving image including a plurality of frame images a respiratory information acquiring unit that performs a respiratory information acquiring processing of acquiring respiratory information synchronized at times at which the frame images are captured, a blood-flow-restricted time determining unit that performs a blood-flow-restricted time determining processing of determining, on the basis of the respiratory information, a blood-flow-restricted time indicating a time at which the blood flow of the target region is assumed to be restricted due to respiration, and a blood flow analysis correcting unit that performs a blood-flow-analysis content correcting processing of excluding the frame image captured at the blood-flow-restricted time from targets for blood flow analysis or decreasing the blood-flow-analysis importance of the frame image compared with another time period.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: May 2, 2017
    Assignee: KONICA MINOLTA, INC.
    Inventors: Kenta Shimamura, Hiroshi Yamato, Osamu Toyama, Shintaro Muraoka, Sho Noji
  • Patent number: 9586058
    Abstract: The idea concerns irradiation of a target volume (53), wherein intensities for target points (70) are determined which are sequentially approached by a beam, comprising the following steps: detecting a volume (63) to be protected, wherein a dose generated by irradiating a target volume (53) does not exceed a predetermined maximum value; determining intensities for target points (70) in such a way that within the volume (63) to be protected the generated dose does not exceed the predetermined maximum value, wherein a dose contribution data record is used for determining the intensities, which dose contribution data record comprises the dose generated at other spots (73) by directing the beam (10) on one of the target points (70) with a predetermined intensity.
    Type: Grant
    Filed: October 17, 2009
    Date of Patent: March 7, 2017
    Assignee: GSI Helmfoltzzentrum fur Schwerinonenforschung GmbH
    Inventors: Christoph Bert, Eike Rietzel, Gerhard Kraft
  • Patent number: 9569687
    Abstract: An image analysis device includes: an acquiring unit configured to acquire a moving image showing a variation of a respiratory status, the moving image being formed with frame images including an image of a heart; an image analyzing unit configured to generate a first index indicating a cardiac status with respect to each of the frame images; and an index analyzing unit configured to derive a second index indicating lung function from a change caused in the first indexes by the respiratory status.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: February 14, 2017
    Assignee: KONICA MINOLTA, INC.
    Inventors: Kenta Shimamura, Osamu Toyama, Koichi Fujiwara, Hiroshi Yamato
  • Patent number: 9463335
    Abstract: A method for planning and monitoring radiopharmaceutical usage during a plurality of radiopharmaceutical injection procedures includes: providing a schedule of the plurality of radiopharmaceutical injection procedures to produce a planned patient schedule; based on the planned patient schedule, calculating a multi-dose container configuration for use during the plurality of radiopharmaceutical injection procedures; transferring the planned patient schedule to a radiopharmaceutical fluid delivery system; loading the multi-dose patient configuration into the radiopharmaceutical fluid delivery system; and conducting the plurality of radiopharmaceutical injection procedures based on the planned patient schedule.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: October 11, 2016
    Assignee: Bayer HealthCare LLC
    Inventors: Scott R. Griffith, James A. Agamaite, Douglas Descalzi, Charles Marsh
  • Patent number: 9402980
    Abstract: According to one general aspect, there is a medical device including a locking mechanism that is used to connect a plurality of catheters, a multi-balloon inflator that inflates multiple balloons on a single catheter, an extraction point used to remove human fluids from the human body, and a connecting point that allows a syringe or a machine to insert liquid saline solution or radioactive isotopes into the multi-balloon inflator.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: August 2, 2016
    Assignee: BEST MEDICAL INTERNATIONAL, Inc.
    Inventor: Manny Subramanian
  • Patent number: 9400333
    Abstract: A survey meter according to the present invention is a portable radiation measurement device. The survey meter comprises a tip portion, an intermediate portion, and a grip portion. A display unit is provided on the top surface of the intermediate portion. The tip portion extends to the intermediate portion with a bent portion therebetween. The tip portion forms an inclined portion. The grip portion has a constricted portion. A radiation detection unit is provided inside the tip portion and is formed by a plurality of sensors arranged in the right-left direction.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: July 26, 2016
    Assignee: HITACHI ALOKA MEDICAL, LTD.
    Inventors: Toshiro Obata, Hiraku Katsuyama
  • Patent number: 9396533
    Abstract: A method for analyzing brain images includes receiving a plurality of three-dimensional image datasets comprising a plurality of voxels for a corresponding plurality of subjects; dividing the plurality of three-dimensional image datasets into at least a first and a second group; dividing the first group into A1 to An subgroups; dividing the second group into B1 to Bn subgroups; determining statistical individual variability between datasets selected from the A1 to An subgroups and the B1 to Bn subgroups; determining statistical individual variability between datasets in the first and second groups responsive to the statistical individual variability between datasets selected from the plurality of three-dimensional image datasets in the A1 to An subgroups and the B1 to Bn subgroups; and for each of the first and second groups, generating a reliability map comprising a map of probabilities that a voxel in an image dataset of the respective first and second groups satisfies a predetermined statistical threshold.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: July 19, 2016
    Inventor: Frank M. Skidmore
  • Patent number: 9390823
    Abstract: There is provided is a radiation image acquiring device which corrects a positional displacement between a collimator and a detector and obtains an image without artifacts. The device includes a detector (21) to measure a radiation; a collimator (26) including a through-hole (27) having one or more detectors (21) disposed therein and configured to limit an incident direction of the radiation; a positional displacement measuring unit configured to measure a positional displacement between the detector (21) and the collimator (26) by use of a profile of a radiation source measured by the detector (21) based on the radiation source disposed corresponding to a predetermined detector (21).
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: July 12, 2016
    Assignee: Hitachi, Ltd.
    Inventors: Atsuro Suzuki, Takafumi Ishitsu, Isao Takahashi, Wataru Takeuchi, Keiji Kobashi
  • Patent number: 9370332
    Abstract: Robotic navigation is provided for nuclear probe imaging. Using a three-dimensional scanner (19), the surface of a patient is determined (42). A calibrated robotic system positions (48) a nuclear probe about the patient based on the surface. The positioning (48) may be without contacting the patient and the surface may be used in reconstruction to account for spacing of the probe from the patient. By using the robotic system for positioning (48), the speed, resolution and/or quality of the reconstructed image may be predetermined, user settable, and/or improved compared to manual scanning. The reconstruction (52) may be more computationally efficient by providing for regular spacing of radiation detection locations within the volume.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: June 21, 2016
    Assignee: SIEMENS MEDICAL SOLUTIONS USA, INC.
    Inventors: Gianluca Paladini, Ali Kamen, Oliver Kutter
  • Patent number: 9320478
    Abstract: Simultaneous dual-isotope positron emission tomography (PET) is used to improve disease evaluation. Two distinct molecular probes are simultaneously provided to the imaging target. One of the probes is labeled with a radionuclide that emits positrons to provide double coincidence events in PET. The other probe is labeled with a radionuclide that emits positrons+prompt gammas to provide triple coincidence events in PET. One of the probes is a metabolic probe, and the other probe is a selective probe that includes a ligand or antibody that is biologically responsive to receptor/antigen status. A PET system is employed that can provide simultaneous double coincidence and triple coincidence PET images. The resulting images provide simultaneous metabolic imaging and receptor/antigen imaging. Applications include disease evaluation, such as cancer staging (e.g., for breast cancer, prostate cancer, etc.).
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: April 26, 2016
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Peter D. Olcott, Craig S. Levin, Sanjiv Sam Gambhir
  • Patent number: 9295408
    Abstract: An apparatus and method perform non-invasive lithium measurement of a patient wherein an apparatus comprising a permanent magnet, and at least one radiofrequency coil tuned to the resonant frequency of one or more isotopes of lithium are coupled to a cavity less than 5 cm in diameter in which a subject's body part (other than the subject's brain) can be inserted, wherein, the concentration of lithium in the subject's body is assessed based on one or more measurements of an amount of lithium detected in the body part without the need for withdrawing fluids from the body.
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: March 29, 2016
    Assignee: WEINBERG MEDICAL PHYSICS LLC
    Inventor: Irving N. Weinberg
  • Patent number: 9275451
    Abstract: A method for analyzing a functional map of at least one tissue of a patient. The method comprises managing a plurality of functional maps each being associated with a plurality of first biological activity indications, receiving a functional map which is associated with a plurality of second biological activity indications, identifying a matching set of the managed functional maps by matching between the plurality of first and second biological activity indications, and using the matching set for a member of a group consisting of: an image data acquisition, a diagnosis of the received functional map, a classification of the received functional map.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: March 1, 2016
    Assignee: Biosensors International Group, Ltd.
    Inventors: Shlomo Ben-Haim, Benny Rousso
  • Patent number: 9223031
    Abstract: A process and device for generating a prototype waveform and a weighting function. The process including obtaining waveforms generated by a detector having at least one photosensor, generating an initial estimate for the prototype waveform and the weighting function and parameterizing the prototype waveform and the weighting function and determining for each waveform an optimal amplitude and an optimal time offset of the prototype waveform.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: December 29, 2015
    Assignees: Kabushiki Kaisha Toshiba, Toshiba Medical Systems Corporation
    Inventors: Kent Burr, Gin-Chung Wang
  • Patent number: 9117133
    Abstract: An apparatus for analyzing a subject including a hyperspectral image module is provided. It is used to identify a suspect region of a subject by using a hyperspectral sensor (for obtaining a hyperspectral image of the subject), a control computer including a processor unit (PU) and a computer readable memory (CRM) (for controlling and is in electronic communication with the sensor), a control software module including instructions stored in the CRM and executed by the PU (for controlling said at least one operating parameter of the sensor), a spectral calibrator module including instructions stored in the CRM and executed by the PU (for applying a wavelength dependent spectral calibration standard constructed for the sensor to a hyperspectral image), and a light source for illuminating the subject. An optional contact probe module is used to collect a signal of the suspect region for medical diagnosis.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: August 25, 2015
    Assignee: Spectral Image, Inc.
    Inventors: Michael Barnes, Zhihong Pan, Sizhong Zhang
  • Patent number: 9078622
    Abstract: A method for selecting data to reconstruct a three-dimensional (3D) image of a subject of interest includes acquiring a 3D emission dataset of the subject of interest, acquiring a respiratory signal of the subject of interest, the respiratory signal including a plurality of respiratory cycles, and calculating a respiratory profile using the respiratory signal. The method further includes, for each respiratory cycle, generating a gating window, calculating a minimum total squared difference (TSD) between a plurality of phases in the respiratory profile and the same plurality of phases in the respiratory cycle, and positioning the gating window based on the TSD values calculated, and reconstructing a 3D image using only the emission data within the plurality of gated windows. A system and non-transitory computer readable medium are also described herein.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: July 14, 2015
    Assignee: General Electric Company
    Inventors: Scott David Wollenweber, Michael George Bonner, Michael Joseph Cook
  • Patent number: 9069089
    Abstract: Positron emission tomography (PET) systems suitable for use with dirty (positron+prompt gamma) emitters are provided. One or more prompt gamma detectors are added to the PET system, where the prompt gamma detectors are responsive to the prompt gammas provided by the dirty emitter, but are not responsive to 511 keV annihilation photons. The prompt gamma detectors can surround the imaging PET detector array and/or be disposed as end caps relative to a generally cylindrical PET detector array. The prompt gamma detectors need not provide spatial resolution, because coincidence events in the PET detector array are classified as 2-photon or 3-photon events depending on whether or not there is a time-coincident signal from the prompt gamma detectors. One application of this approach is dual isotope PET where distinct tracers labeled with clean and dirty positron emitters are simultaneously imaged.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: June 30, 2015
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Peter D. Olcott, Craig S. Levin
  • Patent number: 9060672
    Abstract: A method for coregistering images involves defining middle paths through image objects depicting tissue slices of needle biopsies. First landmarks are defined on a first middle path through a first image object in a first digital image of a first tissue slice, and second landmarks are defined on a second middle path through a second image object of a second digital image of a second tissue slice. Individual first landmarks are associated with individual second landmarks. A first pixel in the first object is coregistered with a second pixel in the second object using multiple first and second landmarks. The first image is displayed in a first frame on a graphical user interface, and the second image is displayed in a second frame such that the first pixel is centered in the first frame, the second pixel is centered in the second frame, and the images have the same orientations.
    Type: Grant
    Filed: February 11, 2013
    Date of Patent: June 23, 2015
    Assignee: Definiens AG
    Inventors: Nicolas Brieu, Melanie Goerner, Guenter Schmidt, Gerd Binnig
  • Patent number: 9037220
    Abstract: A device (1) for use in imaging a subject using both light and gamma rays emanating from the subject, the device including: a first sensor means (2) responsive to light received thereby from the subject to generate first signals (6) for use in forming a first image (10) of the subject; a second sensor means (3) responsive to gamma rays received thereby from the subject to generate second signals (7) for use in forming a second image (11) of the subject and arranged to receive gamma rays from the subject which have passed from the subject through the first sensor means before reaching the second sensor means.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: May 19, 2015
    Assignee: University of Leicester
    Inventors: John Ernest Wyper Lees, Alan Christopher Perkins
  • Publication number: 20150126863
    Abstract: Disclosed is a radiation diagnostic apparatus that includes an examination table that has a length in a first direction, a fixing frame that is fixedly disposed on a floor to be separated from the examination table in the first direction and includes a guide member provided in the first direction, a transfer frame that contacts the guide member and moves along the first direction with respect to the fixing frame, a first rotary arm that is rotatably connected to the transfer frame, and a second rotary arm that is rotatably connected to the first rotary arm and is provided for a radiation source and a radiation detector to face each other.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 7, 2015
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jeong-pil LEE, Su-young KO
  • Publication number: 20150119692
    Abstract: Maximum and minimum dimensional characteristics of a conduit are determined by imaging a portion of the conduit into which an expandable medical device is to be implanted at appropriate points in the cardiac cycle (or other suitable cycle, such as the respiratory cycle, or at other suitable times). The dimensional characteristics of the conduits within the portion of interest may be evaluated and compared to the maximum and minimum dimensional characteristics of the medical device to be implanted in the conduit to determine whether the medical device is of an appropriate size for properly fitting in the conduit.
    Type: Application
    Filed: October 21, 2014
    Publication date: April 30, 2015
    Inventors: Brian McHenry, Victor Okali, Alexander Hill
  • Patent number: 9002438
    Abstract: A system for the measurement of radiation emitted from an in-vivo administered radioactive analyte. The system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 7, 2015
    Assignee: Lucerno Dynamics
    Inventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
  • Publication number: 20150087974
    Abstract: Systems and methods are provided for evaluating tissue for abnormal glucose uptake within a region of interest within a patient. A PET scanner obtains PET imagery including the region of interest and at least part of the liver. An SUV calculator calculates a first set of SUVs representing the region of interest and a second set SUVs representing the liver from the set of at least one PET image. A standardization component calculates a correction value as a function of the second set of SUVs and applies the correction value to either a decision threshold associated with the region of interest or the first set of SUVs. A diagnosis component compares the first set of SUVs to the decision threshold to determine if the glucose uptake within the region of interest is abnormal. A display provides the determination to a user.
    Type: Application
    Filed: September 25, 2014
    Publication date: March 26, 2015
    Inventor: Richard R. Black
  • Patent number: 8989845
    Abstract: A CT imaging system (12) generates structural data of a first FOV which is reconstructed by a CT reconstruction processor (52) into a CT image representation. A nuclear imaging system acquires functional data from a second FOV which is smaller than the first FOV. A first PET reconstruction processor (60) reconstructs the functional data into a PET image representation. A fusion processor (64) combines the PET image representation with a map extracted from the CT image representation to generate an extended FOV image representation. A spill-over correction unit (66) and a backscatter correction unit (68) derive spill-over correction data and backscatter correction data from the extended FOV image representation. A reconstruction processor (70) generates a spill-over and backscatter corrected functional image representation based on the spill-over correction data, the backscatter correction data, and the functional data.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: March 24, 2015
    Assignee: Koninklijke Philips N.V.
    Inventors: Ralph Brinks, Eike G. Gegenmantel