Abstract: Some embodiments of the present inventive concept provide a multispectral imaging system including a first light source, the first light source having a first wavelength configured to produce a non-coherent illumination to image a sample; a second coherent light source, different from the first light source, having a second wavelength, different from the first wavelength, configured to image the sample simultaneously with the first light source; a camera configured to simultaneously receive information related to the first and second light sources from the sample, wherein light at the first wavelength is configured to image a surface of the sample into the camera and light at the second wavelength is configured to penetrate the sample and provide information related to the penetrated sample to the camera; and a processor configured to combine the received information related to the first and second light sources and generate a synthesized image of the anatomical structure and the physiology of blood flow and

Abstract: Disclosed herein is a two-piece sensor assembly that includes an attachment collar configured to attach to a body surface of a patient and comprising at least one opening, and a skin sensor configured to seat into the at least one opening in the attachment collar. The skin sensor includes at least one radiation source configured to irradiate the body surface with at least one interrogation light, and at least one detector configured to detect at least one response light incident from the direction of the body surface.

Abstract: A Raman spectroscopy based system and method for examination and interrogation provides a method for rapid and cost effective screening of various protein-based compounds such as bacteria, virus, drugs, and tissue abnormalities. A hand-held spectroscope includes a laser and optical train for generating a Raman-shifting sample signal, signal processing and identification algorithms for signal conditioning and target detection with combinations of ultra-high resolution micro-filters and an imaging detector array to provide specific analysis of target spectral peaks within discrete spectral bands associated with a target pathogen.

Abstract: Provided is an imaging system including a light source which emits light in at least a portion of a wavelength band of an excitation wavelength with respect to each of a first fluorescent material emitting fluorescence belonging to a near-infrared wavelength band and a second fluorescent material emitting fluorescence belonging to a visible wavelength band, a first image sensor that detects a first fluorescent image of the target in the near-infrared wavelength band, a second image sensor that detects the second fluorescent image of the target in the visible wavelength band, and optics to direct the first fluorescent image to the first image sensor and the second fluorescent image to the second image sensor. The optics include a dichroic film that directs light of the near-infrared wavelength band into a first optical branch and at least a portion of light of the visible wavelength band into a second optical branch, separate from the first optical branch.

Abstract: An user interaction system for performing interaction with a user based on recognition of a sitting posture of the user includes a posture recognition seat including a posture recognition sensor for recognition the sitting posture of the user, and at least one communication module for communication with an external device, a posture mimicking animated device including a communication module for performing communication with the communication module of the posture recognition seat, wherein the posture mimicking animated device visually mimics the sitting posture of the user or visually or audibly guide the sitting posture of the user, in accordance with state information about the sitting posture of the user determined based on a sensing result obtained by the posture recognition sensor, and a mobile application installed in a communication device possessed by the user, wherein the mobile application receives synchronized information related to the sitting posture of the user via communication with the posture

Abstract: A medical instrument is provided and includes a housing and a shaft coupled to the housing. The shaft has a proximal end and a distal end. An end-effector assembly is disposed at the distal end of the shaft. The end-effector assembly includes first and second jaw members. At least one of the first and second jaw members is movable from a first position wherein the first and second jaw members are disposed in spaced relation relative to one another to at least a second position closer to one another wherein the first and second jaw members cooperate to grasp tissue therebetween. The medical instrument also includes one or more light-emitting elements and one or more light-detecting elements configured to generate one or more signals indicative of tissue florescence. The one or more light-emitting elements are adapted to deliver light energy to tissue grasped between the first and second jaw members.

Abstract: A method for increasing accuracy of measurement of body temperature includes a step of collecting an infrared signal to obtain an infrared signal value (step 1), a step of collecting a skin image to obtain a calibrating emissivity (step 2), a step of obtaining a calibrated infrared signal value according to the calibrating emissivity and the infrared signal value obtained in step 1 (step 3), and a step of making a conversion into an actual body temperature (step 4). Accordingly, an actual temperature value of the skin surface can be attained to increase the accuracy of measurement effectively, thereby allowing the measured result to be more close to the real body temperature of a tested target.

Abstract: An imaging apparatus includes: an imaging sensor including a plurality of pixels; a color filter including a plurality of filters arranged to correspond to the pixels; a first light source configured to irradiate a subject with visible light; a second light source configured to irradiate the subject with near-infrared light; a first processor including hardware, the first processor being configured to control an irradiation timing of each of the first light source and the second light source; and a second processor including hardware, the second processor being configured to generate a plurality of pieces of near-infrared image data on different near-infrared regions based on first image data and second image data, the first image data being generated by the imaging sensor by capturing an image of the subject, the second image data being generated by the imaging sensor by capturing an image of the subject.

Abstract: Instruments, systems, and methods for measuring optical density of microbiological samples are provided. In particular, optical density instruments providing improved safety, efficiency, comfort, and convenience are provided. Such optical density instruments include a handheld portion and a base station. The optical density instruments may be used in systems and methods for measuring optical density of biological samples.

Abstract: Provided are an endoscope system and a method of operating the same capable of reliably performing focusing even in a case where an observation target is illuminated with light including long-wave light. A movable lens moves in an optical axis direction. A lens drive unit moves the movable lens from a first lens position of the movable lens where an observation target illuminated with short-wave light is focused to a second lens position of the movable lens where the observation target illuminated with long-wave light having a longer wavelength than the short-wave light is focused.

Abstract: The present application discloses a surface-enhanced Raman scattering (SERS)-active photonic crystal fiber (PCF) probe including a biopsy needle in the PCF probe for integrated sample collection and SERS sensing of one or more analytes comprised in the sample. The PCF comprises solid core and a cladding region surrounding the solid core, wherein the cladding region comprises air holes functionalised by metallic nanoparticles. The application also provides a method for detecting one or more analytes using the PCF probe as well as the use of the PCF probe for the detection of one or more analytes.

Abstract: An infrared detector and an infrared sensor including the infrared detector are provided. The infrared detector includes a plurality of quantum dots spaced apart from each other and including a first component, a first semiconductor layer covering the plurality of quantum dots, and a second semiconductor layer covering the first semiconductor layer.

Abstract: A catheter treatment apparatus comprises an elongate tubular member and an expandable support. The expandable support comprises a radioactive substance to treat cancerous tissue and is configured to expand from a narrow profile for insertion to a wide profile to engage and treat tissue remaining after resection. The expandable support can be sized to fit within a volume of removed tissue to place the radioactive substance in proximity to the capsule and remaining tissue, to spare the capsule and proximate nerves and vessels to treat tissue in proximity to the capsule. The elongate tubular member may comprise a channel such as a lumen to pass a bodily fluid such as urine when the expandable support engages the tissue to treat the patient for a plurality of days. The treatment apparatus can be used to resect and diagnose tissue concurrently. Based on the diagnosis, targeted segmental treatment may be given.

Abstract: A control system having one or more controllers configured to determine physical or psychophysiological (3P) changes of an operator of a vehicle. First and second imaging devices take real-time images of an operator of a vehicle. Then, based on the physical, physiological and/or psychological features extracted from the imaging device data, and a 3P model from historical data the one or more processors also configured to, responsive to the physical, physiological and/or psychological changes of the operator of the vehicle, alert the operator and control the operation of the vehicle.

Abstract: An endoscope system according to the present invention includes: a second illumination unit that emits second illumination light; a first illumination unit that emits, simultaneously with the second illumination light, first illumination light that is light of a different wavelength band from the second illumination light and is for imaging two sets of image information about a subject different depths; an imaging unit that simultaneously images a first illumination image of the subject illuminated with the first illumination light and a second illumination image of the subject illuminated with the second illumination light; a separation processing unit that separates the two sets of image information from the first illumination image; and a separated-image creating unit that processes the second illumination image using the two sets of image information to create separated images.

Abstract: The present invention relates to an imaging device (100) for generating an image of a patient (P), the imaging system (100) comprising: a camera arrangement (10), which is configured to provide a first image information (I1) of the patient (P) using a first wavelength band, and which is configured to provide a second image information (I2) of the patient (P) using a second wavelength band. The first wavelength band and the second set of wavelength band are different; and the first and/or second image information comprises landmark information of landmarks (M) of a patient (P). The landmark information is derived by at least one wavelength band outside the visible spectrum. Further, a data processor (30) is provided, which is configured to generate a fused image (IE) based on the first image information (I1) and the second image information (I2), and which is configured to detect the landmarks (M) in the fused image (IE).

Abstract: Disclosed is an apparatus for observing a tear film on a persons or animals eye. The apparatus comprises an infrared sensitive camera that includes a camera lens system and a computer configured to receive data from the camera, process the data using software and represent the processed data on a display. The camera is configured to measure temporal and spatial changes of thermal radiation from a surface of the eye at a frame rate, a spatial resolution, and a thermal sensitivity that allows the dynamics of the tear film to be visualised. Also disclosed is a method of observing a tear film on an eye of a person or an animal using an apparatus, such as that described above, where the method includes the step of viewing the dynamics of the tear film using the apparatus.

Abstract: The system is configured to locate, track and/or analyze activities of living beings in an environment. The system does not require the input of personal biometric data. The sensor system detects infrared (IR) energy from a living being moving in an environment, determines a temperature of the living being based on IR energy data of the IR energy, projects the temperature onto a grid having sequential pixels, determines serial changes of the temperature in the sequential pixels and determines a trajectory of the living being based on the serial changes of the temperature in the sequential pixels.

Abstract: An eye tracking-based concealed information testing, which includes: presenting images of objects at certain coordinates on a computer display; operating a camera to track eye movements of a human subject observing the display; computing one or more gaze parameters for each of the objects, based on the tracked eye movements and the certain coordinates; and determining that a certain one of the objects is familiar to the human subject based on the gaze parameter. The eye tracking-based concealed information testing is optionally integrated with a short-term memory task, to enhance detection of concealed information.

Abstract: An electronic device, such as a watch, has a housing to which a carrier is attached. The carrier has a first surface interior to the electronic device, and a second surface exterior to the electronic device. A set of electrodes is deposited on the exterior surface of the carrier. An additional electrode is operable to be contacted by a finger of a user of the electronic device while the first electrode is positioned against skin of the user. The additional electrode may be positioned on a user-rotatable crown of the electronic device, on a button of the electronic device, or on another surface of the housing of the electronic device. A processor of the electronic device is operable to determine a biological parameter of the user based on voltages at the electrodes. The biological parameter may be an electrocardiogram.

Abstract: The invention discloses a NIR method for fatty acid content of oilseeds, including: selection of oilseed samples, and analyzing the oilseed samples by an near infrared spectrometer to obtain NIR spectra; preprocessing of NIR spectra and establishment of a NIR spectral database of oilseeds; establishment of a fatty acid database of oilseeds based on gas chromatography; establishment of prediction model of fatty acids in oilseeds; acquiring NIR spectrum of a sample to be tested by the near infrared spectrometer, and importing the preprocessed NIR spectrum into the prediction model of fatty acids to obtain the predicted fatty acid content of the tested sample. The method is simple and rapid to operate and is non-destructive, and the detection time of the sample is greatly shortened and the detection cost is reduced.

Abstract: A method is described for determining a degree of damage to hair, which includes: registering light which is radiated by the hair sample while a hair sample is illuminated with light; based on the registered light, determining first regions of the hair sample which reflect the light with higher interference, and second regions of the hair sample which reflect the light with lower interference; and determining a degree of damage to the hair sample based on the extents of the first regions and of the second regions.

Abstract: A method for displaying information, including receiving measurements, with respect to an invasive probe inside a body of a subject, of probe parameters consisting of a force exerted by the probe on tissue of the subject and temperatures measured by sensors of the probe. The method further includes, responsively to the measurements, displaying in a single map on a display screen a graphical representation of a distribution of the temperatures in a vicinity of the probe and superimposing thereon a vector representation of the force.

Abstract: A system for collecting cannabis and the psychoactive component tetrahydrocannabinol from a sample of exhaled breath is disclosed. Single or multiple exhaled breaths are conditioned by removing contaminants, and regulating flow rate and/or pressure to collect a sample of tetrahydrocannabinol for timely local or remote analysis. The cannabis detection system comprises a containment trap for removing interfering materials from the breath of the subject and a collection component for sampling components of breath introduced into the system through the containment trap for analysis to determine a presence of THC in the breath.

Abstract: A fluctuation-based fluorescence microscopy method, comprising influencing a point-spread function of the imaging of a sample emitting fluorescence radiation using an optical device in dependence on a parameter such that a point emitter is imaged into a representation with two image lobes. The relative positions of the lobes depend on the position of the point emitter relative to the focal plane. Synthetic pixels, smaller than detector pixels, are generated; for each synthetic pixel, pairs of pixel groups are defined among pixels of the detector based on the influencing of the point spread function. Each pair is assigned to an individual value of the parameter. In each frame and for each synthetic pixel, a signal correlation is ascertained and allocated as image brightness to the synthetic pixel for the parameter specification. Subframes for each frame are produced from the synthetic pixels, and a high-resolution sample image is produced from the subframes.

Abstract: The invention relates to a device and an according method for hybrid optoacoustic and ultrasonographic imaging of an object (1), comprising an irradiation unit (2, 3) for irradiating the object (1) with electromagnetic radiation, in particular light, and a transducer unit (4) comprising a plurality of transducer elements (5), the transducer elements (5) being configured to emit ultrasound waves impinging on the object (1) and to detect ultrasound waves which are reflected and/or transmitted by the object (1) upon impinging on the object (1), and to detect ultrasound waves which are generated in the object (1) upon irradiation with electromagnetic radiation, wherein the transducer elements (1) are arranged along a curved line, in particular a concave line, or a curved surface, in particular a concave surface.

Abstract: A method includes generating spectral image data reproducible as one or more spectral images of a plurality of regions of interest in a sample. The method also includes analyzing the spectral image data to identify a plurality of scattering components in the spectral image data, each of the plurality of scattering components being associated with one or more biological properties of the sample. The method also includes identifying a feature of interest in the sample based at least in part on one or more the identified plurality of scattering components.

Abstract: Systems and methods for time-resolved spectroscopy. Exemplary methods include: providing first, second, and third light using an excitation source; receiving first scattered light from a material responsive to the providing the first light; signaling the detector, after a delay, to provide a first spectrum of the received first scattered light; receiving second scattered light from the material responsive to the providing the second light; signaling the detector, after the delay, to provide a second spectrum of the received second scattered light; receiving third scattered light from the material responsive to the providing the third light; signaling the detector, after the delay, to provide a third spectrum of the received third scattered light; recovering a spectrum of the material using the first spectrum, second spectrum, and third spectrum; and identifying at least one molecule of the material using the recovered spectrum and a database of identified spectra.

Abstract: A surgical system used to determine a size of a vessel within a region proximate to a working end of a surgical instrument includes at least one light emitter disposed at the working end of the surgical instrument, and at least one light sensor disposed at the working end of the surgical instrument opposite the at least one light emitter, the at least one light sensor adapted to generate a signal comprising a first pulsatile component and a second non-pulsatile component. The system also includes a controller coupled to the at least one light sensor, the controller comprising a splitter to separate the first pulsatile component from the second non-pulsatile component and an analyzer to quantify the size of the vessel within the region proximate to the working end of the surgical instrument based on the first pulsatile component.

Abstract: The present disclosure is directed towards a medical instrument. The medical instrument includes a housing and an end effector assembly operably connected to the housing. The end effector assembly includes first and second jaw members each having a tissue contacting surface, at least one of the first and second jaw members movable between a first, spaced-apart position and a second proximate position, wherein in the second position, the jaw members cooperate to define a cavity configured to receive tissue between the jaw members. The end effector also includes at least one light-emitting element coupled to at least one of the first and second jaw members, the at least one light-emitting element adapted to deliver light energy to tissue grasped between the first and second jaw members to treat the tissue.

Abstract: Image data representing an image captured by a video endoscopic device is converted from a first color space to a second color space. The image data in the second color space is used to determine the location of features in the image.

Abstract: A method is disclosed for analyzing image data from a patient after a minimally invasive intervention on a lesion, in particular after a tumor ablation on a tumor, wherein a pre-intervention image dataset showing the lesion and an intra- and/or post-intervention, second image dataset showing the intervention region are analyzed. In at least one embodiment of the method, the method includes deriving attribute data describing attributes of the image data from the image datasets at least in part automatically, the attribute data being usable as input data to an artificial intelligence analysis algorithm trained using training data from other patients, and the training data being associated with a ground truth. The method further includes determining, from the attribute data, change information that describes the change in the lesion and/or in the intervention region as a result of the intervention.

Abstract: Methods and systems for characterizing tissue of a subject are disclosed. The method includes receiving a time series of fluorescence images of the tissue of the subject wherein the images define a plurality of calculation regions, generating a plurality of time-intensity curves for the plurality of calculation regions, creating a set of parameter values for each calculation region, generating a total rank value for each calculation region by comparing the sets of parameter values, and converting the total rank value into a ranking map image. Also disclosed are methods and systems for characterizing a wound in tissue by generating a wound index value.

Abstract: A medical image processing apparatus includes: a medical image acquisition unit that acquires a medical image; a medical image analysis result acquisition unit that acquires an analysis result of the medical image; a display unit that displays the medical image and the analysis result; a correspondence relationship setting unit that sets a correspondence relationship between a first analysis result of a first medical image and a second analysis result of a second medical image having different imaging conditions from the first medical image; and a display control unit that sets a display form in case of displaying the second analysis result on the first medical image using the set correspondence relationship or sets a display form in case of displaying the first analysis result on the second medical image using the set correspondence relationship.

Abstract: A device and method is described for electronic human prosthetics, and specifically a body-machine interface (BMI) device where the input, output and on-board computing are combined into a single unit to form a compact ECG, respiratory sensing, temperature-sensing-prosthetics device. The devices (BMIs) can also communicate with other body-machine interface devices (BMI) and/or with external controllers wirelessly. The compact device has ultrasonic battery charging system. One or more BMI can be wirelessly connected so that a closed loop of BMIs, or a BMI and an external controller, can wirelessly send trigger pulses to the stimulator over the heart, glossopharyngeal nerve(s) or diaphragm.

Abstract: A furniture system includes an office productivity structure (OPS). The furniture system also includes a sensor coupled to the OPS, the sensor operable to detect a parameter of the OPS and generate an output signal indicative of the parameter; and a processor coupled to the sensor. The processor is operable to receive the output signal generated by the sensor, determine, based on the output signal, an operation condition of the OPS, when the operation condition is determined to be within a satisfactory range, determine an estimated time before servicing is needed, and when the operation condition is determined to be outside a satisfactory range, send a service alert.

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

Abstract: A medical imaging device includes: a spectroscopic unit that separates light into a first light component of a wavelength band and a second light component; a first imaging element that includes a plurality of first pixels configured to receive the first light component and convert the first light component into electric signals; and a second imaging element that includes a plurality of second pixels and includes a first color filter on which first filters configured to transmit the light component of the wavelength band of one color in the light components of the wavelength bands of two colors that are contained in the second light component and second filters configured to transmit light components of a plurality of wavelength bands including at least the wavelength band of another color in the light components of the wavelength bands of the two colors are arranged.

Abstract: A pattern recognition system receives an image captured by an image capture device, of an operator and the operator is identified. Operator information is accessed, based upon the identified operator, and a control signal is generated to control a mobile machine, based upon the operator information.

Abstract: An endoscopic system having a light source that can operate in two modes is provided. The first mode provides a white light to an endoscope to transmit the light to a surgical site or other object, the reflection of which can be received by the endoscope and for the process. The second mode of the light source provides infrared excitation light and light in the blue and green wavelength spectra to an endoscope to transmit the light to an object such as a surgical site. The blue and green reflected light, as well as light from excitation markers, which is an infrared light at a different wavelength than the excitation infrared light, is received by the endoscope and further processed.

Abstract: A medical image viewing device for navigation in X-ray imaging includes a processor. The processor is configured to perform a 3D-2D registration of a preoperative three-dimensional volume based on geometry parameters of an image data provider, which provides fluoroscopy images of an object of interest and a plurality of structures with interfering motions to be removed, for creating digitally reconstructed radiograph images of these structures for each fluoroscopy image. These are subtracted from the respective fluoroscopy images to generate structure-suppressed fluoroscopy images free from interfering motions. Based on these structure-suppressed fluoroscopy images, an angiographic image sequence is generated performing a motion estimation of the structures.

Abstract: Disclosed herein is a ladar system that includes a ladar transmitter, ladar receiver, and camera, where the camera that is co-bore sited with the ladar receiver, the camera configured to generate image data corresponding to a field of view for the ladar receiver. In an example embodiment, a mirror can be included in the optical path between a lens and photodetector in the ladar receiver, where the mirror (1) directs light within the light from the lens that corresponds to a first light spectrum in a first direction for reception by the camera and (2) directs light within the light from the lens that corresponds to a second light spectrum in a second direction for reception by the photodetector, wherein the second light spectrum includes ladar pulse reflections for processing by the ladar system.

Abstract: Systems and methods are disclosed to measure a PPG signal. In some embodiments, a method may include capturing a plurality of frames of a subject; tracking the position of a region of interest of the subject in each of the plurality of frames; creating a first time series signal, a second time series signal, and third time series signal corresponding with respective color channels of the plurality of frames; normalizing the first, second, and third time series signals, combining the normalized first time series signal, the normalized first time series signal, and the normalized first time series signal into a combined signal; creating a spectral signal from the combined signal; and extracting the PPG signal from the spectral signal.

Abstract: The present disclosure relates to a cabinet x-ray and ultrasound system and method for obtaining x-ray images and ultrasound images of a specimen and more specifically, a system and method including a cabinet defining an interior chamber, a display, an x-ray system and an ultrasound system.

Abstract: Sample handling, processing and analysis methods and apparatus are described. According to one aspect, a sample processing method includes providing a sample, providing a reference frame which comprises a plurality of markers arranged in a predefined pattern, wherein individual ones of the markers are uniquely identifiable from others of the markers, and associating the reference frame comprising the markers with the sample. The markers are amenable to human or machine reading and for computational manipulation in some examples.

Abstract: A light sensing method applied to a light sensing system comprising a first light sensor and at least one light source. The first light sensor comprises a plurality of light sensing units. The light sensing method comprises: (a) respectively controlling an exposure condition for each of the light sensing units according distances between each one of the light sensing units and the light source; and (b) controlling the light sensing units to sense the light from the light source according to the exposure condition. The light sensing system can have a better SNR via adjusting the exposure condition for each one of the light sensing units. Such light sensing method can be applied to compute physiological parameters.

Abstract: An example method for estimating a disease state for a patient can include: capturing physiological data including images from the patient over time; processing the physiological data to detect a variability; comparing the variability to a baseline or a range; and estimating the disease state for the patient based upon the comparing of the variability to the baseline or the limit.

Abstract: A radiotherapy system including a radiotherapy component, a structural imaging component, a functional imaging component, and a workstation coupled to the radiotherapy component, the structural imaging component, and the functional imaging component. The workstation includes a processor which combines the structural imaging data and the functional imaging data to produce a fused model for a least a portion of the region of interest, to generate a plan for radiotherapy treatment of the region of interest based on the fused model, and apply, via the radiotherapy component, the radiotherapy treatment.

Abstract: Disclosed herein is a method for regenerating retinal tissue which includes preparing a luminescent scaffold, implanting the luminescent scaffold in a portion of retina, for example subretinal area, emitting a green light from the luminescent nanoparticles in a luminescence phenomenon, and absorbing the emitted light by retinal cells for regenerating retinal tissue by stimulating the retinal cells. Moreover, preparing a luminescent scaffold may comprise synthesizing a plurality of luminescent particles, dispersing the luminescent particles in a polymeric matrix to form a luminescent composite, and electrospinning the luminescent composite to form the luminescent scaffold.

Abstract: A dual-mode optical molecular imaging navigation apparatus with a switchable field of view, and an imaging method thereof, are provided in the embodiments of the disclosure, the apparatus including: a camera module configured to perform a color imaging and a fluorescence imaging; a switching module configured to switch between an open imaging mode and an endoscopic imaging mode as per imaging requirements; an open imaging module configured to perform observation and imaging with a large field of view; an endoscopic imaging module configured to perform observation and imaging with a deep field of view; a data processing module configured to provide a camera control software and image capturing, processing and display method; and a support module configured to support and connect the navigation apparatus.