Abstract: A method or use for managing one or more acute ischemic events. The method can include determining criteria of a clot; classifying the clot based on the criteria and generating a classification; determining an individualized treatment protocol for the clot based on the classification, the individualized treatment protocol comprising one or more techniques selected from using aspiration, restoring perfusion using a first reperfusion device, and/or restoring perfusion using a second reperfusion device; and treating the clot based on the individualized treatment protocol.

Abstract: According to various embodiments, an electronic device may include a first communication circuit and at least one first processor. At least one first processor is configured to: obtain, via the communication circuit, a plurality of images including a user's face obtained by using a camera of a first external electronic device; obtain first data obtained based on a first sensor of the first external electronic device contacted with a first portion of a body of the user and second data obtained based on a second external electronic device contacting a second portion of the body of the user while obtaining the plurality of images, while simultaneously acquiring the plurality of images; and obtain a first biometric signal of a specific type based on the images, a second biometric signal of the specific type based on the first data, and a third biometric signal based on the second data.

Abstract: Systems and methods for granting access to a user to a resource associated with a telecommunications network based on network-based authentication combined with biometric authentication, such as using a cardiac signature. Heartbeat information is received from a user via a mobile device. When a match is determined between the heartbeat information and a stored cardiac signature that uniquely identifies the user, then the user is authenticated to use the mobile device. A second authentication is performed using subscriber identity module (SIM) information associated with the mobile device. Based on the first and second authentication, the user is granted access to a resource associated with the telecommunications network, such as resources provided by a telecommunications service provider or a third party.

Abstract: A sensor device is described herein. The sensor device includes a multi-dimensional optical sensor and processing circuitry, wherein the multi-dimensional optical sensor generates images and the processing circuitry is configured to output data that is indicative of hemodynamics of a user based upon the images. The sensor device is non-invasive, and is able to be incorporated into wearable devices, thereby allowing for continuous output of the data that is indicative of the hemodynamics of the user.

Abstract: A method for evaluating cardiac diastolic function, which applies to the field of cardiac monitoring. The method comprises: obtaining vibration information of the surface of the thoracic cavity of a subject by means of one or more optical fiber sensors; preprocessing the vibration information to generate hemodynamic related information; performing high-frequency component extraction on the hemodynamic related information to generate high-frequency component information; determining a first feature value and a second feature value based on the hemodynamic related information and the high-frequency component information; generating indicating parameters based on the first feature value and the second feature value, and evaluating the cardiac diastolic function of the subject based on the indicating parameters.

Abstract: An example system for estimating a hydration level of an individual can include: a mechanism configured to apply mechanical pressure to a digit of the individual; an light detector configured to sense the light from the digit; and a controller programmed to perform functions including: send a first signal to the mechanism to apply the mechanical pressure to the digit; send a second signal to the mechanism to release the mechanical pressure on the digit; determine a capillary refill time based upon a third signal from the light detector indicating an amount of time for capillaries of the individual to refill with blood; and estimate the hydration level of the individual based upon the capillary refill time and one or more additional parameters.

Abstract: A system and method of combining different sensor data for higher reliable diagnosis information on a portable mobile device includes using a camera for imaging a region of interest of a subject to obtain an image signal, a microphone for capturing acoustic information from the subject, and one or more processors. The one or more processors can be configured to spectrally analyze the image signal, estimate a first vital-sign of the subject corresponding to a diagnosis using the image signal, analyze the acoustic information, estimate a second vital-sign of the subject corresponding to the diagnosis using the acoustic information, and combine the first vital sign with the second vital-sign to provide a higher confidence level diagnostic of the diagnosis.

Abstract: The present invention is directed to systems and process for detecting a febrile condition in screening of multiple or large groups of persons for the likelihood of infectious diseases. The system comprises a temperature measurement device having at least a processor, a display, temperature sensor, camera module, and facial recognition software. The display may include a positional overlay. The system further includes a database containing baseline temperatures for a number of persons, including baseline temperatures by age group and by gender. An input device optionally may identify the specific person or provide survey questions to a person to further determine a febrile condition. Based on the baseline temperatures, measured temperature and other characteristics of the person, a febrile condition may be determined. Additionally, the system may include a secondary screening component providing nasal swabbing or saliva testing.

Abstract: A grip-type pulse wave measuring device includes a main body that has a substantially spheroid shape, and a stopper that projects along an axial direction of the main body and abuts against a side surface of a thumb to restrict a position of the thumb when a user grips the main body portion. Moreover, a light shielding cover is provided that is formed into a substantially semi-cylindrical shape and is mounted so as to be swingable about, as a swing shaft, a shaft that is provided in parallel to the axial direction of the main body. A photoplethysmographic sensor is disposed at a position offset from the swing shaft of the light shielding cover along a peripheral direction of the main body and is configured to acquire a photoplethysmographic signal.

Abstract: Particular embodiments described herein provide for an apparatus to determine biometric data of a user including: a processing circuit configured to: generate a control signal relating to a control value for controlling a wavelength of emitted light of a light source; receive biometric input data based on reflected light from the skin of the user caused by the light of the wavelength emitted by the light source; and determine biometric data of the user based on the biometric input data; and an output interface configured to provide the biometric data of the user.

Abstract: Provided is an apparatus configured to detect a light signal, the apparatus including a light source configured to radiate light toward an object, a light receiver configured to receive an ambient light and a transmitted light corresponding to the light radiated toward the object from the light source, at least one processor configured to control the light source to be turned off such that a first output signal is generated by the light receiver and control the light source to be turned on such that a second output signal is generated by the light receiver, and an operator configured to generate a transmitted light signal from which noise is removed by differentially operating the second output signal from the first output signal.

Abstract: An electronic device, a method to be executed by an electronic device, and a non-transitory memory storing a program for causing an electronic device to execute processes include acquiring a pulse wave of a subject, and estimating a blood glucose level and/or a lipid level of the subject based on a displacement ratio in the pulse wave. The displacement ratio comprises a ratio between a displacement of the pulse wave at a peak of the pulse wave and a displacement of the pulse wave at a predetermined time after the peak of the pulse wave, and the predetermined time is a fixed value.

Abstract: An automated system for acquiring images of one or more capillaries in a capillary bed includes a platform for receiving a body portion of a subject, an imaging subsystem having a repositionable field of view and coupled to the platform to acquire images of at least a capillary bed of the body portion and a controller communicably coupled to the imaging subsystem to automatically reposition the field of view of the imaging subsystem to different areas of the capillary bed, and at each field of view within the capillary bed, activate the imaging subsystem to acquire images of one or more capillaries in the capillary bed.

Abstract: An authentication system for authenticating an identification of a subject is provided. The authentication system includes a photoplethysmogram (PPG) sensor, a storage device, and a processor. The PPG sensor is configured to sense pulses of a blood vessel of the subject to generate a sensed PPG signal of the subject. The storage device stores an authentication model. The processor is configured to load the authentication model from the storage device and input the sensed PPG signal and a reference PPG signal into the authentication model to generate a result value which indicates whether the identification of the subject passes an authentication test.

Abstract: A mobile device may comprise: a power source, one or more sensors, a communication device, and an actuator. The power source can be configured to provide power to one or more components of the mobile device. The one or more sensors can be configured to generate sensor data. The communication device can be removably coupled to the power source to receive power therefrom and can be further configured to communicate with one or more computing devices remote to the mobile device. The actuator can be configured to transition between at least a first state and a second state to cause the communication device to electrically disconnect from the power source to terminate communication of the communication device with the one or more computing devices remote to the mobile device. The one or more sensors can be configured to generate sensor data when the actuator is in the first state or the second state.

Abstract: Relationships between morphological changes to an eye due to intraocular pressure changes and blood perfusion changes in the retina are determined by colocalizing retinal perfusion data and optic nerve head (ONH) mechanical deformation data. Perfusion changes from intraocular pressure (IOP) changes are determined by colocalizing retinal perfusion data with ONH mechanical deformation data. Optical coherence tomography-angiography (OCT-A) can be used to generate both retinal perfusion data and mechanical deformation data for an imaged volume. A three-dimensional model (e.g., connectivity map or connectivity model) of the vasculature can be generated from the OCT-A imaging data and used to predict changes in blood perfusion in various areas of the retina due to IOP-induced mechanical deformations.

Abstract: Methods, systems, and devices for optical signal measurement are described. A wearable electronic device may activate a first combination of optical sensors, the first combination of optical sensors including a set of transmitter sensors and a set of receiver sensors. In some cases, one or more optical sensor of the first combination of optical sensors may be positioned under a protrusion on an inner surface of the wearable electronic device. The device may measure, at the set of receiver sensors at a first time, one or more signals from the set of transmitter sensors, determine a signal quality metric associated with the one or more signals, and select a second combination of optical sensors for use at a second time based on the signal quality metric.

Abstract: An apparatus for estimating cardiovascular information includes: a main body; and a strap connected to the main body and formed to be flexible to be wrapped around an object, wherein the main body may include: a pulse wave measurer configured to measure, from the subject, a first pulse wave signal by using a first light of a first wavelength, and a second pulse wave signal by using a second light of a second wavelength, the first wavelength being different from the second wavelength; a contact pressure measurer configured to measure a contact pressure between the object and the pulse wave measurer; and a processor configured to extract a cardiovascular characteristic value based on the first pulse wave signal, the second pulse wave signal, and change in the contact pressure, and estimate cardiovascular information based on the extracted cardiovascular characteristic value.

Abstract: An integrated window for a photosensor for use in an electronic device has first and second transparent regions separated by an opaque region. The first transparent region allows a transmitter to emit light out of the housing of the electronic device and the second transparent region allows a receiver to receive light through the housing. The opaque region is disposed between the first and second transparent regions to isolate them from one another such that the transmitted light is isolated from the received light.

Abstract: A method for estimating a measure of cardiovascular health of a subject (102) comprises: receiving (302) an electrocardiogram, ECG, signal (202); receiving (304) an artery signal (210) representative of pressure pulse wave propagation at a location in an artery; determining (306) a fiducial point in time based on the ECG signal (202) providing an indication of onset of isovolumetric contraction; determining (308) a pre-systolic pressure pulse arrival point in time (212) based on the artery signal (210) to correspond to the onset of the isovolumetric contraction being reflected in the artery signal (210), determining (310) a time period between the onset of the isovolumetric contraction and the pre-systolic pressure pulse arrival point in time, said time period representing a vascular transit time; and determining (312) a pulse wave velocity of the subject (102) based on a physical distance between an aortic valve and the location in the artery and on the vascular transit time.

Abstract: A lateral flow assay device comprising a conjugate pad for receiving a quantity of fluid, and a membrane comprising a test line for determining whether the fluid comprises a target analyte. The device includes an actuator connected to a moving element comprising a shaft or a wheel. A first magnet is connected to the backing of the membrane. Second and third magnets are connected to the moving element. The actuator moves the moving element between first and second positions. In the first position, the opposite poles of the first and second magnets attract each other and maintain a gap between the membrane and the conjugate pad separate. In the second position, the similar poles of the first and third magnets repel each other and close the gap between membrane and the conjugate pad, allowing the fluid to flow from the conjugate pad into the membrane and the test line.

Abstract: A biometric apparatus includes a light source, an image sensor, a control circuit, and a signal processing circuit. The control circuit causes a light source to repeatedly emit a light pulse radiated onto a target part including a head of a target, causes an image sensor to receive a reflected light pulse which is caused as the light pulse is radiated onto the target part, causes the image sensor to output first image data indicating appearance of a face of the target, and causes the image sensor to output second image data according to distribution of an amount of light of at least one of components of the reflected light pulse. The signal processing circuit generates data indicating a state of the target based on a temporal change in the first image data and a temporal change in the second image data and outputs the data.

Abstract: A system for displaying information indicative of driving conditions, to a driver, using a smart ring are disclosed. An exemplary system includes a smart ring with a ring band having a plurality of surfaces including an inner surface, an outer surface, a first side surface, and a second side surface. The system further includes a processor, configured to obtain data from a communication module within the ring band, or from one or more sensors disposed within the ring band. The obtained data are representative of information indicative of one or more driving conditions to be displayed to the driver. The smart ring also includes a light emitting diode (LED) display disposed on at least one of the plurality of surfaces, and configured to present information indicative of the one or more driving conditions.

Abstract: Techniques for predicting fluid responsiveness or fluid unresponsiveness are described. A processor can determine a first prediction of fluid responsiveness or unresponsiveness based on a plethysmograph variability parameter associated with a plethysmograph waveform, and can determine a second prediction of fluid responsiveness or unresponsiveness based on a fluid responsiveness parameter that is associated with an elevation of one or more limbs of the patient. The processor can determine an overall prediction of fluid responsiveness or unresponsiveness based on the first and/or second predictions. Based on overall prediction, the processor can cause administration of fluids and/or termination of administration of fluids.

Abstract: A near-infrared spectroscopy system comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.

Abstract: A fingerprint identification circuit, a display panel, and a control method thereof. A first electrical signal is generated by a light sensation circuit in that fingerprint identification circuit according to the detected optical signal reflected by the finger, potential information of the first electrical signal is stored in a holding circuit, and a second electrical signal for fingerprint identification is output by a scanning circuit according to the potential information of the first electrical signal stored in the holding circuit, so that the fingerprint identification device can complete the collection of the electrical signals output by all the fingerprint identification circuits set by the fingerprint identification device in the case that the residence time of the user's finger is short, thereby supporting the design of fingerprint identification circuits with larger area and higher density in the optical fingerprint identification device.

Abstract: Laser-Speckle Contrast imaging apparatus configured to assess and quantify motion associated with an object and, in a specific case of an eye—retinal vascular anatomy and hemodynamics and generate substantially contrast-free maps of retinal blood flow over a wide field-of-view at up to 590 fps and under short exposure durations (>50 ?s), is applicable for diagnosis, study, and management of neurodegenerative conditions (i.e. mild cognitive impairment and Alzheimer's disease) and systemic cardiovascular diseases (i.e. athero- and arteriosclerosis, coronary artery occlusion, and hypertension). The apparatus employs a) a set of apertures substantially blocking light, delivered from a source of light to an illumination arm of the apparatus, from impinging onto an axial point of the front surface of the lens of the illumination arm, and b) polarization gating between the illumination and light-collecting arms of the apparatus.

Abstract: Present embodiments pertain to systems, apparatuses, and methods for analyzing and reporting the movements in mechanical structures, inanimate physical structures, machinery, and machine components, including automatically detecting aliased frequencies of a component on the structure which exhibits frequencies higher than the maximum frequency of the FFT spectrum calculated from the acquired data. To automatically detect the presence of aliased frequencies, a second virtually identical recording is acquired using a slightly different sampling rate and this provides the basis for detecting frequencies which are greater than the Nyquist sampling rate of the video recording and calculating the true frequency value of the aliased peaks in the frequency spectrum.

Abstract: A system for non-invasive hematological measurements includes a platform to receive a body portion of a user and an imaging device to acquire a set of images of a capillary bed in the body portion. For each image, a controller detects one or more capillaries in the body portion of the finger to identify a first set of capillaries by estimating one or more attributes of each capillary (e.g., structural attributes, flow attributes, imaging attributes, or combinations thereof), wherein at least one attribute of each capillary meets a predetermined criterion. The controller also identifies a second set of capillaries from the first set of capillaries such that each capillary of the second set of capillaries is visible in a predetermined number of images of the set of images.

Abstract: In some embodiments, systems, methods, and media for capsule-based multimode endoscopy are provided. In some embodiments, a probe for capsule-based multimode endoscopy is provided, the probe comprising: a rigid capsule; a flexible tether coupled to a proximal end of the capsule; a rotatable reflective surface disposed within the capsule; a static ball lens disposed within the capsule; a first optical fiber optically coupled to the ball lens, the first optical fiber passing through the flexible tether; a second optical fiber optically coupled to the ball lens, the second optical fiber passing through the flexible tether; a graded index fiber disposed between a distal end of the second optical fiber and the ball lens, the graded index fiber optically coupled to the second optical fiber and the ball lens.

Abstract: An apparatus for estimating bio-information, includes a pulse wave sensor configured to measure a pulse wave signal from a user, and a processor configured to obtain two or more parameters among a maximum point, an average point, and an onset point, from a waveform of the measured pulse wave signal, and combine the obtained two or more parameters to generate a pulse wave analysis result.

Abstract: An optical coherence imager for use in a clinical environment includes a laser source (24) for illuminating an area of tissue surface and a detector array (28) arranged to generate output signals indicative of detected light scattered from the tissue surface. An optical coherence image, such as a Flux image that is indicative of blood perfusion in the tissue, is generated from data collected at the detector. Detector output is analysed to identify a time series of such optical coherence images during which relative movement between tissue and detector is favourable. A representative optical coherence image is formed from an average of optical coherence images generated from data collected within the identified time series and extending over a period of multiple heartbeats. The representative optical coherence image thereby exhibits minimal movement noise and the effects of heartbeat are averaged out.

Abstract: Disclosed is a photoplethysmography (PPG) apparatus (100) for determining physiological changes, comprising: a light source to emit alight signal having a variable intensity dependent on a skin characteristic; first and second photodetectors (130) operable to detect a reflection of the light signal to provide a combined current signal; and a signal processing circuit operable to convert the current signal into a PPG signal for determining the physiological changes.

Abstract: One or more devices, systems, methods, and storage mediums for optical imaging medical devices, such as, but not limited to, Optical Coherence Tomography (OCT), single mode OCT, and/or multi-modal OCT apparatuses and systems, and methods and storage mediums for use with same, for triggering auto-pullback, including for devices or systems using blood clearing, are provided herein. Examples of applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Techniques provided herein also improve processing and imaging efficiency while achieving images that are more precise.

Abstract: An optical apparatus for non-invasively measuring a bio-signal is provided. The optical apparatus may include an interface housing including: a guide part defined by an interior space of the interface housing and configured to guide an object to a measurement position; and a pressurizing part configured to induce congestion of a second portion of the object by pressing a first portion of the object when the object is disposed within the guide part; and a measurer including: a light source provided on an upper side of the interface housing and configured to emit light to the second portion of the object when the object is at the measurement position; and a detector configured to measure a bio-signal from the second portion by detecting light scattered or reflected from the second portion.

Abstract: An apparatus for non-invasively measuring bio-information is provided. The apparatus for estimating bio-information may include a pulse wave sensor configured to measure a pulse wave signal from an object; a sensor position sensor configured to obtain sensor position information of the pulse wave sensor with respect to the object, based on the object being in contact with the pulse wave sensor; and a processor configured to estimate the bio-information based on blood vessel position information of the object, the sensor position information, and the pulse wave signal.

Abstract: Disclosed are methods and devices useful for imaging blood-containing tissue, for example for angiography, especially retinal angiography, whereby an image is generated by dividing pixels of an image acquired at some wavelength range by corresponding pixels of an image acquired at a different wavelength range. In some embodiments, a first wavelength range includes predominantly light having wavelengths between about 400 nm and about 620 nm and a second wavelength range includes predominantly light having wavelengths between about 620 nm and about 800 nm.

Abstract: Provided is an apparatus for non-invasively monitoring a health condition. The apparatus for monitoring health according to an example embodiment of the disclosure includes: a pulse wave sensor configured to obtain a first pulse wave signal in a first contact state of an object and a second pulse wave signal in a second contact state of the object; and a processor configured to estimate a degree of vasodilation based on an alternating current (AC) component of each of the first pulse wave signal and the second pulse wave signal, configured to monitor a vascular health condition based on the estimated degree of vasodilation, and configured to output a result of monitoring the vascular health condition.

Abstract: A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.

Abstract: Systems and methods for granting access to a user to a resource associated with a telecommunications network based on network-based authentication combined with biometric authentication, such as using a cardiac signature. Heartbeat information is received from a user via a mobile device. When a match is determined between the heartbeat information and a stored cardiac signature that uniquely identifies the user, then the user is authenticated to use the mobile device. A second authentication is performed using subscriber identity module (SIM) information associated with the mobile device. Based on the first and second authentication, the user is granted access to a resource associated with the telecommunications network, such as resources provided by a telecommunications service provider or a third party.

Abstract: A wearable device and a method for performing a registration process in the wearable device are provided. The wearable device includes a light source, a light sensor and a microcontroller that performs the method. In the method, the light source is activated to emit a detection light and the light sensor senses a reflected light. A light intensity of the reflected light is calculated. A registration value is produced based on the light intensity. Specifically, the detection light with a specific frequency to be registered in the registration value is used as a reference to detect whether the wearable device is properly worn by a person. For example, since the wearable device can be worn on the person's wrist, the registration value is used to detect whether the wearable device is away from the wrist.

Abstract: Systems are provided for detecting the flow of blood in vasculature by illuminating the blood with a source of coherent illumination and detecting one or more time-varying properties of a light speckle pattern that results from the scattering of the coherent illumination by tissue and blood. The movement of blood cells and other light-scattering elements in the blood causes transient, short-duration changes in the speckle pattern. High-frequency sampling or other high-bandwidth processing of a detected intensity at one or more points in the speckle pattern could be used to determine the flow of blood in the vasculature. Such flow-measuring systems are also presented as wearable devices that can be operated to detect the flow in vasculature of a wearer. Systems and methods provided herein can additionally be applied to measure flow in other scattering fluid media, for example in a scattering industrial, medical, pharmaceutical, or environmental fluid.

Abstract: Provided herein are medical devices, systems and platforms to monitor tissue properties such as oxygen saturation, temperature and degree of tissue edema for diagnosis and post-operative patient monitoring. The medical devices may be handheld or portable or may be removable patches. The medical devices utilize light of various visible and near-infrared wavelengths to interrogate a tissue where the intensities of reflected light correlate to one or more tissue property. Also provided are methods for measuring tissue properties, for detecting pressure ulcers and for remotely monitoring in real time a surgical flap on a post-operative subject via the medical devices.

Abstract: A method, a structure, and a computer system for a modular sensing unit. The structure comprises a sensor module, a power cable ribbon, and a component module, wherein the component module is in communication with and detachable from the sensor module via the power cable ribbon.

Abstract: An apparatus, method and computer program is described comprising: receiving video data for a scene; determining a movement measurement for at least some of a plurality of subframes of the video data; weighting the movement measurements to generate a plurality of weighted movement measurements, wherein the weighting is dependent on the subframe; and generating a movement indication for the scene from a combination of some or all of the weighted movement measurements.

Abstract: An electronic device can include a housing defining an aperture and at least partially defining an internal volume of the electronic device, an electromagnetic radiation emitter and an electromagnetic radiation detector disposed in the internal volume, and an optical component disposed in the aperture. The optical component can include a first and second transparent portions disposed above the electromagnetic radiation detector and the electromagnetic radiation emitter, and an opaque portion disposed between the first and second transparent portions. A conductive component can be in electrical communication with the opaque portion and one or more components of the electronic device.

Abstract: An electronic device can include a housing defining an aperture and at least partially defining an internal volume of the electronic device, an electromagnetic radiation emitter and an electromagnetic radiation detector disposed in the internal volume, and an optical component disposed in the aperture. The optical component can include a first and second transparent portions disposed above the electromagnetic radiation detector and the electromagnetic radiation emitter, and an opaque portion disposed between the first and second transparent portions and extending a thickness of the optical component. The first transparent portion, the second transparent portion, and the opaque portion can define a flush exterior surface of the electronic device.

Abstract: A method for determining one or more physiological parameters of a subject. The method includes providing a plurality of images of a vessel of the subject in response to illumination of the vessel to light of different wavelengths; converting each of the plurality of images of the vessel into at least two grayscale images, thereby generating a plurality of first grayscale images of a first wavelength range and a plurality of second grayscale images of a second wavelength range, the first wavelength range and the second wavelength range being different from each other; and determining the one or more physiological parameters of the subject based on at least the plurality of first grayscale images and the plurality of second grayscale images.

Abstract: According to the present application, a computer-implemented method of predicting thyroid eye disease is disclosed. The method comprising: preparing a conjunctival hyperemia prediction model, a conjunctival edema prediction model, a lacrimal edema prediction model, an eyelid redness prediction model, and an eyelid edema prediction model, obtaining a facial image of an object, obtaining a first processed image and a second processed image from the facial image, wherein the first processed image is different from the second processed image, obtaining predicted values for each of a conjunctival hyperemia, a conjunctival edema and a lacrimal edema by applying the first processed image to the conjunctival hyperemia prediction model, the conjunctival edema prediction model, and the lacrimal edema prediction model, and obtaining predicted values for each of an eyelid redness and an eyelid edema by applying the second processed image to the eyelid redness prediction model and the eyelid edema prediction model.

Abstract: The disclosure provides a heart rate monitor (HRM) circuit. The HRM circuit includes an analog front end (AFE). The AFE receives a Photoplethysmographic (PPG) signal, and generates a fine PPG signal. A motion cancellation circuit is coupled to the AFE, and receives the fine PPG signal and an accelerometer signal. The motion cancellation circuit subtracts the accelerometer signal from the fine PPG signal to generate a coarse heart rate. A peak detector is coupled to the motion cancellation circuit and the AFE, and generates an instantaneous heart rate. A filter is coupled to the peak detector, and generates an estimated heart rate from the instantaneous heart rate, the estimated heart rate is provided as a feedback to the peak detector.