Cardiovascular Testing Patents (Class 600/479)
  • Patent number: 12131217
    Abstract: An automated system for acquiring images of one or more capillaries in a capillary bed includes a platform for receiving a body portion of a subject, an imaging subsystem having a repositionable field of view and coupled to the platform to acquire images of at least a capillary bed of the body portion and a controller communicably coupled to the imaging subsystem to automatically reposition the field of view of the imaging subsystem to different areas of the capillary bed, and at each field of view within the capillary bed, activate the imaging subsystem to acquire images of one or more capillaries in the capillary bed.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: October 29, 2024
    Assignee: LEUKO LABS, INC.
    Inventors: Ian Butterworth, Carlos Castro-Gonzalez, Aurelien Bourquard, Alvaro Sanchez Ferro, Ganimete Lamaj, Nolan Bell, Ryan Benasutti, Alberto Pablo-Trinidad
  • Patent number: 12124548
    Abstract: An authentication system for authenticating an identification of a subject is provided. The authentication system includes a photoplethysmogram (PPG) sensor, a storage device, and a processor. The PPG sensor is configured to sense pulses of a blood vessel of the subject to generate a sensed PPG signal of the subject. The storage device stores an authentication model. The processor is configured to load the authentication model from the storage device and input the sensed PPG signal and a reference PPG signal into the authentication model to generate a result value which indicates whether the identification of the subject passes an authentication test.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: October 22, 2024
    Assignee: MEDIATEK INC.
    Inventors: Hung-Chih Chiu, En Jen
  • Patent number: 12126683
    Abstract: A mobile device may comprise: a power source, one or more sensors, a communication device, and an actuator. The power source can be configured to provide power to one or more components of the mobile device. The one or more sensors can be configured to generate sensor data. The communication device can be removably coupled to the power source to receive power therefrom and can be further configured to communicate with one or more computing devices remote to the mobile device. The actuator can be configured to transition between at least a first state and a second state to cause the communication device to electrically disconnect from the power source to terminate communication of the communication device with the one or more computing devices remote to the mobile device. The one or more sensors can be configured to generate sensor data when the actuator is in the first state or the second state.
    Type: Grant
    Filed: August 31, 2022
    Date of Patent: October 22, 2024
    Assignee: Masimo Corporation
    Inventors: Peter Koo, Massi Joe E. Kiani, Bilal Muhsin, Omar Ahmed, Richard Priddell
  • Patent number: 12074637
    Abstract: Methods, systems, and devices for optical signal measurement are described. A wearable electronic device may activate a first combination of optical sensors, the first combination of optical sensors including a set of transmitter sensors and a set of receiver sensors. In some cases, one or more optical sensor of the first combination of optical sensors may be positioned under a protrusion on an inner surface of the wearable electronic device. The device may measure, at the set of receiver sensors at a first time, one or more signals from the set of transmitter sensors, determine a signal quality metric associated with the one or more signals, and select a second combination of optical sensors for use at a second time based on the signal quality metric.
    Type: Grant
    Filed: October 11, 2022
    Date of Patent: August 27, 2024
    Assignee: Oura Health Oy
    Inventors: Tero Juhani Vallius, Olli Petteri Heikkinen, Jussi Petteri Järvelä, Heikki Juhani Huttunen, Teemu Juhani Haverinen, Antti Aleksi Rantanen, Sami Seppo Pelkonen, Juha-Pekka Syrjälä, Markku Olavi Koskela
  • Patent number: 12070271
    Abstract: Relationships between morphological changes to an eye due to intraocular pressure changes and blood perfusion changes in the retina are determined by colocalizing retinal perfusion data and optic nerve head (ONH) mechanical deformation data. Perfusion changes from intraocular pressure (IOP) changes are determined by colocalizing retinal perfusion data with ONH mechanical deformation data. Optical coherence tomography-angiography (OCT-A) can be used to generate both retinal perfusion data and mechanical deformation data for an imaged volume. A three-dimensional model (e.g., connectivity map or connectivity model) of the vasculature can be generated from the OCT-A imaging data and used to predict changes in blood perfusion in various areas of the retina due to IOP-induced mechanical deformations.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: August 27, 2024
    Assignee: THE UAB RESEARCH FOUNDATION
    Inventors: Massimo Antonio Fazio, Christopher Anthony Girkin
  • Patent number: 12064265
    Abstract: An integrated window for a photosensor for use in an electronic device has first and second transparent regions separated by an opaque region. The first transparent region allows a transmitter to emit light out of the housing of the electronic device and the second transparent region allows a receiver to receive light through the housing. The opaque region is disposed between the first and second transparent regions to isolate them from one another such that the transmitted light is isolated from the received light.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: August 20, 2024
    Assignee: APPLE INC.
    Inventors: Adam T. Clavelle, Maegan K. Spencer, Jaden Alyssa Barney, Dale N. Memering, Ueyn L. Block, Paul D. Mannheimer
  • Patent number: 12064270
    Abstract: An apparatus for estimating cardiovascular information includes: a main body; and a strap connected to the main body and formed to be flexible to be wrapped around an object, wherein the main body may include: a pulse wave measurer configured to measure, from the subject, a first pulse wave signal by using a first light of a first wavelength, and a second pulse wave signal by using a second light of a second wavelength, the first wavelength being different from the second wavelength; a contact pressure measurer configured to measure a contact pressure between the object and the pulse wave measurer; and a processor configured to extract a cardiovascular characteristic value based on the first pulse wave signal, the second pulse wave signal, and change in the contact pressure, and estimate cardiovascular information based on the extracted cardiovascular characteristic value.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: August 20, 2024
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jae Min Kang, Yong Joo Kwon, Seung Woo Noh, Sang Yun Park
  • Patent number: 12059234
    Abstract: A method for estimating a measure of cardiovascular health of a subject (102) comprises: receiving (302) an electrocardiogram, ECG, signal (202); receiving (304) an artery signal (210) representative of pressure pulse wave propagation at a location in an artery; determining (306) a fiducial point in time based on the ECG signal (202) providing an indication of onset of isovolumetric contraction; determining (308) a pre-systolic pressure pulse arrival point in time (212) based on the artery signal (210) to correspond to the onset of the isovolumetric contraction being reflected in the artery signal (210), determining (310) a time period between the onset of the isovolumetric contraction and the pre-systolic pressure pulse arrival point in time, said time period representing a vascular transit time; and determining (312) a pulse wave velocity of the subject (102) based on a physical distance between an aortic valve and the location in the artery and on the vascular transit time.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: August 13, 2024
    Assignee: STICHTING IMEC NEDERLAND
    Inventors: Fabian Beutel, Evelien Hermeling
  • Patent number: 12042260
    Abstract: A biometric apparatus includes a light source, an image sensor, a control circuit, and a signal processing circuit. The control circuit causes a light source to repeatedly emit a light pulse radiated onto a target part including a head of a target, causes an image sensor to receive a reflected light pulse which is caused as the light pulse is radiated onto the target part, causes the image sensor to output first image data indicating appearance of a face of the target, and causes the image sensor to output second image data according to distribution of an amount of light of at least one of components of the reflected light pulse. The signal processing circuit generates data indicating a state of the target based on a temporal change in the first image data and a temporal change in the second image data and outputs the data.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: July 23, 2024
    Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.
    Inventors: Yumiko Ohno, Kenji Narumi, Tsuguhiro Korenaga, Jin Muraoka, Satoshi Arimoto, Takamasa Ando
  • Patent number: 12044650
    Abstract: A lateral flow assay device comprising a conjugate pad for receiving a quantity of fluid, and a membrane comprising a test line for determining whether the fluid comprises a target analyte. The device includes an actuator connected to a moving element comprising a shaft or a wheel. A first magnet is connected to the backing of the membrane. Second and third magnets are connected to the moving element. The actuator moves the moving element between first and second positions. In the first position, the opposite poles of the first and second magnets attract each other and maintain a gap between the membrane and the conjugate pad separate. In the second position, the similar poles of the first and third magnets repel each other and close the gap between membrane and the conjugate pad, allowing the fluid to flow from the conjugate pad into the membrane and the test line.
    Type: Grant
    Filed: April 7, 2022
    Date of Patent: July 23, 2024
    Assignee: 2Pi-Sigma Corp.
    Inventor: Mehdi Hatamian
  • Patent number: 12027048
    Abstract: A system for displaying information indicative of driving conditions, to a driver, using a smart ring are disclosed. An exemplary system includes a smart ring with a ring band having a plurality of surfaces including an inner surface, an outer surface, a first side surface, and a second side surface. The system further includes a processor, configured to obtain data from a communication module within the ring band, or from one or more sensors disposed within the ring band. The obtained data are representative of information indicative of one or more driving conditions to be displayed to the driver. The smart ring also includes a light emitting diode (LED) display disposed on at least one of the plurality of surfaces, and configured to present information indicative of the one or more driving conditions.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: July 2, 2024
    Assignee: BLUEOWL, LLC
    Inventor: Kenneth Jason Sanchez
  • Patent number: 12004869
    Abstract: Techniques for predicting fluid responsiveness or fluid unresponsiveness are described. A processor can determine a first prediction of fluid responsiveness or unresponsiveness based on a plethysmograph variability parameter associated with a plethysmograph waveform, and can determine a second prediction of fluid responsiveness or unresponsiveness based on a fluid responsiveness parameter that is associated with an elevation of one or more limbs of the patient. The processor can determine an overall prediction of fluid responsiveness or unresponsiveness based on the first and/or second predictions. Based on overall prediction, the processor can cause administration of fluids and/or termination of administration of fluids.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: June 11, 2024
    Assignee: Masimo Corporation
    Inventors: Massi Joe E. Kiani, Bilal Muhsin, Keith Ward Indorf
  • Patent number: 11974843
    Abstract: A near-infrared spectroscopy system comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.
    Type: Grant
    Filed: April 4, 2022
    Date of Patent: May 7, 2024
    Assignee: NIRSense LLC
    Inventors: Jared Dale Allen, Bretton Robert Goldbach, Areej Habib, Jason Michael Strohmaier, Ryan Casey Boutwell
  • Patent number: 11974812
    Abstract: Laser-Speckle Contrast imaging apparatus configured to assess and quantify motion associated with an object and, in a specific case of an eye—retinal vascular anatomy and hemodynamics and generate substantially contrast-free maps of retinal blood flow over a wide field-of-view at up to 590 fps and under short exposure durations (>50 ?s), is applicable for diagnosis, study, and management of neurodegenerative conditions (i.e. mild cognitive impairment and Alzheimer's disease) and systemic cardiovascular diseases (i.e. athero- and arteriosclerosis, coronary artery occlusion, and hypertension). The apparatus employs a) a set of apertures substantially blocking light, delivered from a source of light to an illumination arm of the apparatus, from impinging onto an axial point of the front surface of the lens of the illumination arm, and b) polarization gating between the illumination and light-collecting arms of the apparatus.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: May 7, 2024
    Assignees: The Medical College of Wisconsin, Inc., Coherence Consulting LLC
    Inventors: Dwani Patel, Al Hafeez Dhalla, Christian B. Viehland, Daniel M. Lipinski
  • Patent number: 11978279
    Abstract: A fingerprint identification circuit, a display panel, and a control method thereof. A first electrical signal is generated by a light sensation circuit in that fingerprint identification circuit according to the detected optical signal reflected by the finger, potential information of the first electrical signal is stored in a holding circuit, and a second electrical signal for fingerprint identification is output by a scanning circuit according to the potential information of the first electrical signal stored in the holding circuit, so that the fingerprint identification device can complete the collection of the electrical signals output by all the fingerprint identification circuits set by the fingerprint identification device in the case that the residence time of the user's finger is short, thereby supporting the design of fingerprint identification circuits with larger area and higher density in the optical fingerprint identification device.
    Type: Grant
    Filed: July 27, 2023
    Date of Patent: May 7, 2024
    Assignee: Hefei Visionox Technology Co., Ltd.
    Inventors: Dongsheng Li, Qingrong Ren, Feng Qi, Shuang Cui, Shiwen Hu, Rubo Xing
  • Patent number: 11972577
    Abstract: Present embodiments pertain to systems, apparatuses, and methods for analyzing and reporting the movements in mechanical structures, inanimate physical structures, machinery, and machine components, including automatically detecting aliased frequencies of a component on the structure which exhibits frequencies higher than the maximum frequency of the FFT spectrum calculated from the acquired data. To automatically detect the presence of aliased frequencies, a second virtually identical recording is acquired using a slightly different sampling rate and this provides the basis for detecting frequencies which are greater than the Nyquist sampling rate of the video recording and calculating the true frequency value of the aliased peaks in the frequency spectrum.
    Type: Grant
    Filed: December 21, 2022
    Date of Patent: April 30, 2024
    Assignee: RDI TECHNOLOGIES, INC.
    Inventors: Kenneth Ralph Piety, Jeffrey R. Hay, Mark William Slemp
  • Patent number: 11963661
    Abstract: In some embodiments, systems, methods, and media for capsule-based multimode endoscopy are provided. In some embodiments, a probe for capsule-based multimode endoscopy is provided, the probe comprising: a rigid capsule; a flexible tether coupled to a proximal end of the capsule; a rotatable reflective surface disposed within the capsule; a static ball lens disposed within the capsule; a first optical fiber optically coupled to the ball lens, the first optical fiber passing through the flexible tether; a second optical fiber optically coupled to the ball lens, the second optical fiber passing through the flexible tether; a graded index fiber disposed between a distal end of the second optical fiber and the ball lens, the graded index fiber optically coupled to the second optical fiber and the ball lens.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: April 23, 2024
    Assignee: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Kanwarpal Singh
  • Patent number: 11963750
    Abstract: A system for non-invasive hematological measurements includes a platform to receive a body portion of a user and an imaging device to acquire a set of images of a capillary bed in the body portion. For each image, a controller detects one or more capillaries in the body portion of the finger to identify a first set of capillaries by estimating one or more attributes of each capillary (e.g., structural attributes, flow attributes, imaging attributes, or combinations thereof), wherein at least one attribute of each capillary meets a predetermined criterion. The controller also identifies a second set of capillaries from the first set of capillaries such that each capillary of the second set of capillaries is visible in a predetermined number of images of the set of images.
    Type: Grant
    Filed: February 7, 2022
    Date of Patent: April 23, 2024
    Assignees: Massachusetts Institute of Technology, Universidad Politecnica De Madrid
    Inventors: Carlos Castro-Gonzalez, Ian Butterworth, Aurelien Bourquard, Alvaro Sanchez Ferro, Jason Tucker-Schwartz, Alberto Pablo Trinidad, Maria J. Ledesma Carbayo, Tom Vettenburg
  • Patent number: 11950891
    Abstract: An apparatus for estimating bio-information, includes a pulse wave sensor configured to measure a pulse wave signal from a user, and a processor configured to obtain two or more parameters among a maximum point, an average point, and an onset point, from a waveform of the measured pulse wave signal, and combine the obtained two or more parameters to generate a pulse wave analysis result.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: April 9, 2024
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Dae Geun Jang
  • Patent number: 11950894
    Abstract: An optical coherence imager for use in a clinical environment includes a laser source (24) for illuminating an area of tissue surface and a detector array (28) arranged to generate output signals indicative of detected light scattered from the tissue surface. An optical coherence image, such as a Flux image that is indicative of blood perfusion in the tissue, is generated from data collected at the detector. Detector output is analysed to identify a time series of such optical coherence images during which relative movement between tissue and detector is favourable. A representative optical coherence image is formed from an average of optical coherence images generated from data collected within the identified time series and extending over a period of multiple heartbeats. The representative optical coherence image thereby exhibits minimal movement noise and the effects of heartbeat are averaged out.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: April 9, 2024
    Assignee: Moore Instruments Limited
    Inventors: Rodney John Gush, Xiabing Huang
  • Patent number: 11944778
    Abstract: One or more devices, systems, methods, and storage mediums for optical imaging medical devices, such as, but not limited to, Optical Coherence Tomography (OCT), single mode OCT, and/or multi-modal OCT apparatuses and systems, and methods and storage mediums for use with same, for triggering auto-pullback, including for devices or systems using blood clearing, are provided herein. Examples of applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Techniques provided herein also improve processing and imaging efficiency while achieving images that are more precise.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: April 2, 2024
    Assignee: Canon U.S.A., Inc.
    Inventor: Badr Elmaanaoui
  • Patent number: 11944416
    Abstract: Disclosed is a photoplethysmography (PPG) apparatus (100) for determining physiological changes, comprising: a light source to emit alight signal having a variable intensity dependent on a skin characteristic; first and second photodetectors (130) operable to detect a reflection of the light signal to provide a combined current signal; and a signal processing circuit operable to convert the current signal into a PPG signal for determining the physiological changes.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: April 2, 2024
    Assignee: Nitto Denko Corporation
    Inventors: Estanislao Glenn Bondice, Suppasit Chuwatsawat, Wiputpong Klinsukon, Somchai Baotong, Visit Thaveeprungsriporn
  • Patent number: 11937921
    Abstract: An optical apparatus for non-invasively measuring a bio-signal is provided. The optical apparatus may include an interface housing including: a guide part defined by an interior space of the interface housing and configured to guide an object to a measurement position; and a pressurizing part configured to induce congestion of a second portion of the object by pressing a first portion of the object when the object is disposed within the guide part; and a measurer including: a light source provided on an upper side of the interface housing and configured to emit light to the second portion of the object when the object is at the measurement position; and a detector configured to measure a bio-signal from the second portion by detecting light scattered or reflected from the second portion.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: March 26, 2024
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Bok Soon Kwon, Woochang Lee, So Young Lee
  • Patent number: 11911134
    Abstract: An apparatus for non-invasively measuring bio-information is provided. The apparatus for estimating bio-information may include a pulse wave sensor configured to measure a pulse wave signal from an object; a sensor position sensor configured to obtain sensor position information of the pulse wave sensor with respect to the object, based on the object being in contact with the pulse wave sensor; and a processor configured to estimate the bio-information based on blood vessel position information of the object, the sensor position information, and the pulse wave signal.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: February 27, 2024
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jin Woo Choi, Sang Yun Park, Hye Rim Lim, Jae Min Kang, Seung Woo Noh
  • Patent number: 11911188
    Abstract: Provided is an apparatus for non-invasively monitoring a health condition. The apparatus for monitoring health according to an example embodiment of the disclosure includes: a pulse wave sensor configured to obtain a first pulse wave signal in a first contact state of an object and a second pulse wave signal in a second contact state of the object; and a processor configured to estimate a degree of vasodilation based on an alternating current (AC) component of each of the first pulse wave signal and the second pulse wave signal, configured to monitor a vascular health condition based on the estimated degree of vasodilation, and configured to output a result of monitoring the vascular health condition.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: February 27, 2024
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: So Young Lee, Jeong Eun Hwang, Ka Ram Choi
  • Patent number: 11911138
    Abstract: Disclosed are methods and devices useful for imaging blood-containing tissue, for example for angiography, especially retinal angiography, whereby an image is generated by dividing pixels of an image acquired at some wavelength range by corresponding pixels of an image acquired at a different wavelength range. In some embodiments, a first wavelength range includes predominantly light having wavelengths between about 400 nm and about 620 nm and a second wavelength range includes predominantly light having wavelengths between about 620 nm and about 800 nm.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: February 27, 2024
    Assignees: Tel HaShomer Medical Research Infrastructure and Services Ltd., Ramot At Tel AvivUniversity Ltd.
    Inventors: Genady Kostenich, Arie Orenstein, Michael Belkin
  • Patent number: 11903677
    Abstract: A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.
    Type: Grant
    Filed: October 4, 2021
    Date of Patent: February 20, 2024
    Assignee: Avinger, Inc.
    Inventors: John B. Simpson, Himanshu N. Patel, Michael Zung, Charles W. McNall, Priyanshu Gupta, Maegan K. Spencer, Christopher B. White, Dennis W. Jackson, John F. Black
  • Patent number: 11877218
    Abstract: Systems and methods for granting access to a user to a resource associated with a telecommunications network based on network-based authentication combined with biometric authentication, such as using a cardiac signature. Heartbeat information is received from a user via a mobile device. When a match is determined between the heartbeat information and a stored cardiac signature that uniquely identifies the user, then the user is authenticated to use the mobile device. A second authentication is performed using subscriber identity module (SIM) information associated with the mobile device. Based on the first and second authentication, the user is granted access to a resource associated with the telecommunications network, such as resources provided by a telecommunications service provider or a third party.
    Type: Grant
    Filed: July 13, 2021
    Date of Patent: January 16, 2024
    Assignee: T-Mobile USA, Inc.
    Inventor: David Moffett
  • Patent number: 11864864
    Abstract: A wearable device and a method for performing a registration process in the wearable device are provided. The wearable device includes a light source, a light sensor and a microcontroller that performs the method. In the method, the light source is activated to emit a detection light and the light sensor senses a reflected light. A light intensity of the reflected light is calculated. A registration value is produced based on the light intensity. Specifically, the detection light with a specific frequency to be registered in the registration value is used as a reference to detect whether the wearable device is properly worn by a person. For example, since the wearable device can be worn on the person's wrist, the registration value is used to detect whether the wearable device is away from the wrist.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: January 9, 2024
    Assignee: PIXART IMAGING INC.
    Inventors: Chun-Chih Chen, Yung-Chang Lin, Ming-Hsuan Ku
  • Patent number: 11857301
    Abstract: Systems are provided for detecting the flow of blood in vasculature by illuminating the blood with a source of coherent illumination and detecting one or more time-varying properties of a light speckle pattern that results from the scattering of the coherent illumination by tissue and blood. The movement of blood cells and other light-scattering elements in the blood causes transient, short-duration changes in the speckle pattern. High-frequency sampling or other high-bandwidth processing of a detected intensity at one or more points in the speckle pattern could be used to determine the flow of blood in the vasculature. Such flow-measuring systems are also presented as wearable devices that can be operated to detect the flow in vasculature of a wearer. Systems and methods provided herein can additionally be applied to measure flow in other scattering fluid media, for example in a scattering industrial, medical, pharmaceutical, or environmental fluid.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: January 2, 2024
    Assignee: Verily Life Sciences LLC
    Inventors: Andrew Homyk, Russell Norman Mirov
  • Patent number: 11857294
    Abstract: Provided herein are medical devices, systems and platforms to monitor tissue properties such as oxygen saturation, temperature and degree of tissue edema for diagnosis and post-operative patient monitoring. The medical devices may be handheld or portable or may be removable patches. The medical devices utilize light of various visible and near-infrared wavelengths to interrogate a tissue where the intensities of reflected light correlate to one or more tissue property. Also provided are methods for measuring tissue properties, for detecting pressure ulcers and for remotely monitoring in real time a surgical flap on a post-operative subject via the medical devices.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: January 2, 2024
    Assignee: The Texas A&M University System
    Inventors: John Hanks, Amir Tofighi Zavareh, Michel Saint-Cyr
  • Patent number: 11850068
    Abstract: A method, a structure, and a computer system for a modular sensing unit. The structure comprises a sensor module, a power cable ribbon, and a component module, wherein the component module is in communication with and detachable from the sensor module via the power cable ribbon.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: December 26, 2023
    Assignee: International Business Machines Corporation
    Inventors: Rajeev Narayanan, Bing Dang, Katsuyuki Sakuma
  • Patent number: 11816846
    Abstract: An apparatus, method and computer program is described comprising: receiving video data for a scene; determining a movement measurement for at least some of a plurality of subframes of the video data; weighting the movement measurements to generate a plurality of weighted movement measurements, wherein the weighting is dependent on the subframe; and generating a movement indication for the scene from a combination of some or all of the weighted movement measurements.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: November 14, 2023
    Assignee: NOKIA TECHNOLOGIES OY
    Inventors: Mahendran Subramanian, Aldo Faisal
  • Patent number: 11805629
    Abstract: An electronic device can include a housing defining an aperture and at least partially defining an internal volume of the electronic device, an electromagnetic radiation emitter and an electromagnetic radiation detector disposed in the internal volume, and an optical component disposed in the aperture. The optical component can include a first and second transparent portions disposed above the electromagnetic radiation detector and the electromagnetic radiation emitter, and an opaque portion disposed between the first and second transparent portions. A conductive component can be in electrical communication with the opaque portion and one or more components of the electronic device.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: October 31, 2023
    Assignee: APPLE INC.
    Inventors: Maegan K. Spencer, Brian R. Land, Naoto Matsuyuki, Erik L. Wang, William C. Lukens, Steven C. Roach
  • Patent number: 11786139
    Abstract: An electronic device can include a housing defining an aperture and at least partially defining an internal volume of the electronic device, an electromagnetic radiation emitter and an electromagnetic radiation detector disposed in the internal volume, and an optical component disposed in the aperture. The optical component can include a first and second transparent portions disposed above the electromagnetic radiation detector and the electromagnetic radiation emitter, and an opaque portion disposed between the first and second transparent portions and extending a thickness of the optical component. The first transparent portion, the second transparent portion, and the opaque portion can define a flush exterior surface of the electronic device.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: October 17, 2023
    Assignee: APPLE INC.
    Inventors: Maegan K. Spencer, Brian R. Land, Naoto Matsuyuki, Erik L. Wang, William C. Lukens, Steven C. Roach
  • Patent number: 11751766
    Abstract: A method for determining one or more physiological parameters of a subject. The method includes providing a plurality of images of a vessel of the subject in response to illumination of the vessel to light of different wavelengths; converting each of the plurality of images of the vessel into at least two grayscale images, thereby generating a plurality of first grayscale images of a first wavelength range and a plurality of second grayscale images of a second wavelength range, the first wavelength range and the second wavelength range being different from each other; and determining the one or more physiological parameters of the subject based on at least the plurality of first grayscale images and the plurality of second grayscale images.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: September 12, 2023
    Assignee: BOE Technology Group Co., Ltd.
    Inventor: Cheng Liu
  • Patent number: 11748884
    Abstract: According to the present application, a computer-implemented method of predicting thyroid eye disease is disclosed. The method comprising: preparing a conjunctival hyperemia prediction model, a conjunctival edema prediction model, a lacrimal edema prediction model, an eyelid redness prediction model, and an eyelid edema prediction model, obtaining a facial image of an object, obtaining a first processed image and a second processed image from the facial image, wherein the first processed image is different from the second processed image, obtaining predicted values for each of a conjunctival hyperemia, a conjunctival edema and a lacrimal edema by applying the first processed image to the conjunctival hyperemia prediction model, the conjunctival edema prediction model, and the lacrimal edema prediction model, and obtaining predicted values for each of an eyelid redness and an eyelid edema by applying the second processed image to the eyelid redness prediction model and the eyelid edema prediction model.
    Type: Grant
    Filed: January 6, 2023
    Date of Patent: September 5, 2023
    Assignee: THYROSCOPE INC.
    Inventors: Kyubo Shin, Jaemin Park, Jongchan Kim
  • Patent number: 11747178
    Abstract: A physiological monitor gauge panel defines parameters to display on a physiological monitor via corresponding gauges. Gauge faces depict a range of parameter values for each of the parameters. An indicator designates a position on each gauge face corresponding to the current parameter value within the range of parameter values. The indicated position on each of the gauges is at the mid-point of each of the gauge faces when each of the parameters is at a nominal value.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: September 5, 2023
    Assignee: Masimo Corporation
    Inventors: Ammar Al-Ali, Bilal Muhsin, Keith Indorf, Massi Joe E. Kiani
  • Patent number: 11744520
    Abstract: The disclosure provides a heart rate monitor (HRM) circuit. The HRM circuit includes an analog front end (AFE). The AFE receives a Photoplethysmographic (PPG) signal, and generates a fine PPG signal. A motion cancellation circuit is coupled to the AFE, and receives the fine PPG signal and an accelerometer signal. The motion cancellation circuit subtracts the accelerometer signal from the fine PPG signal to generate a coarse heart rate. A peak detector is coupled to the motion cancellation circuit and the AFE, and generates an instantaneous heart rate. A filter is coupled to the peak detector, and generates an estimated heart rate from the instantaneous heart rate, the estimated heart rate is provided as a feedback to the peak detector.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: September 5, 2023
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Sarma Sundareswara Gunturi, Sunil Chomal
  • Patent number: 11737708
    Abstract: This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wristwatch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: August 29, 2023
    Assignee: Purdue Research Foundation
    Inventors: Jacqueline Callihan Linnes, Orlando Sanguinette Hoilett, Ashlyn Twibell, Hyowon Lee, Rohit Srivastava, Jason D Ummel, Ryan Lindsey
  • Patent number: 11730427
    Abstract: Systems and methods for assessing PPG signals generated based on transdermal optical data can include a computing device generating a color intensity signal using an acquired sequence of transdermal images of a subject. The computing device can compute a signal quality metric of the color intensity signal. The computing device can provide an indication of a quality of the color intensity signal for display on a display device associated with the computing device. The indication of the quality of the color intensity signal can be determined based on the signal quality metric.
    Type: Grant
    Filed: October 27, 2021
    Date of Patent: August 22, 2023
    Assignee: BIOSPECTAL SA
    Inventors: Eliott Jones, Jean-Francois Knebel, Urvan Christen, Frederic Frappereau, Patrick Schoettker
  • Patent number: 11723535
    Abstract: The invention relates to a device and a method for examining the retinal vascular endothelial function of the vessels of the retina at the fundus (F) of a patient's eye. Using a fundus camera, the vessels of the retina are stimulated with flicker light during a stimulation phase and sequences of images of areas of the fundus (F) are recorded, from which vascular parameters are derived which describe the retinal vascular endothelial function of the vessels. By imaging a macula stop (MB), which covers the macula, onto the fundus (F), the fundus (F) can be illuminated with a higher light intensity, which improves the stimulation effect and the image quality and/or reduces the strain on the patient.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: August 15, 2023
    Assignee: IMEDOS SYSTEMS GMBH
    Inventors: Walthard Vilser, Jens Haueisen, Sascha Klee, Dietmar Link, Thomas Riemer, Martin Skorsetz
  • Patent number: 11720146
    Abstract: Controlled-environment facility resident behavioral and/or health monitoring may employ controlled-environment facility resident wearables each having a band configured to be affixed around a portion of a controlled-environment facility resident, irremovable by the resident and may include sensor(s) configured to measure biometric(s) of the controlled-environment facility resident and one or more physical parameter(s) experienced by the wearable, with a transmitter transmitting the biometric(s) and/or the physical parameter(s) to a controlled-environment facility management system.
    Type: Grant
    Filed: December 9, 2022
    Date of Patent: August 8, 2023
    Assignee: Securus Technologies, LLC
    Inventor: Scott Passe
  • Patent number: 11701055
    Abstract: Aspects of the present disclosure provide methods, apparatuses, and systems for accurately determining sleep and wake onset based on a user's personalized physiological parameters for sleep and wake. First, a user is determined to be asleep using population level data. Thereafter, sensor collected data is used to determine the user's distribution of values of a physiological parameter when the user is asleep. This distribution of values is then used, instead of population-level data, to determine the user is asleep in real-time. As a result, the content and interventions are provided to help users get back to sleep. Further, the described techniques allow more accuracy in determining sleep statistics which can guide recommended interventions and therapies.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: July 18, 2023
    Assignee: BOSE CORPORATION
    Inventors: Thomas Charles Blanchard, Darasy Reth
  • Patent number: 11700462
    Abstract: There is provided a system for performing ambient light image correction. The system comprises a light source, a rolling shutter imaging unit configured to capture a plurality of images of the object at an exposure time shorter than the wave period of the pulsed illumination from the light source, and a control unit configured to generate a first composite image comprising a plurality of bright bands from the plurality of captured images by combining sections from the plurality of captured images which correspond to bright bands, generate a second composite image comprising a plurality of dark bands from the plurality of captured images by combining sections from the plurality of captured images which correspond to dark bands, and generate an ambient light corrected image based on a difference in pixel information between the first composite image and the second composite image.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: July 11, 2023
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Jonathan Alambra Palero, Yannyk Parulian Julian Bourquin, Rieko Verhagen, Kiran Kumar Thumma
  • Patent number: 11684265
    Abstract: A disease prediction apparatus may include: a spectrometer configured to obtain an optical spectrum of a subject; and a processor configured to predict autofluorescence of the subject based on the optical spectrum by applying the optical spectrum to an autofluorescence prediction model, and predict a risk of developing a cardiovascular disease based on the predicted autofluorescence.
    Type: Grant
    Filed: September 1, 2021
    Date of Patent: June 27, 2023
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Eui Seok Shin, Yun S Park
  • Patent number: 11684301
    Abstract: In accordance with one embodiment of the present disclosure, a method includes generating a plurality of icons, wherein each icon has a target frequency unique from each other, receiving brain activity data based on an epoch, generating a reference signal based on the epoch, calculating correlation coefficients between the brain activity data and the reference signal, wherein the correlation coefficients are calculated in a window that is within ±0.5 Hz of the target frequencies, including endpoints, determining a confidence score based on the correlation coefficients and the epoch, and determining a selected icon among the plurality of icons based on the correlation coefficients in response to the confidence score surpassing a threshold confidence score.
    Type: Grant
    Filed: January 14, 2022
    Date of Patent: June 27, 2023
    Assignees: TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC., UNIVERSITY OF CONNECTICUT HEALTH CENTER
    Inventors: Insoo Kim, Hossein Hamidi Shishavan, Kia Golzari, Muhamed Farooq
  • Patent number: 11684279
    Abstract: Disclosed are a system and a method for determining a probability for a person to have arrhythmia. The system comprises means for measuring heartbeat interval of the person for a period of time; an accelerometer; means for measuring an electrocardiogram of the person; a user interface for providing information and alerts, and a processor. The processor is configured to detect a period of rest of the person, based on measurement data from the accelerometer; analyze the measured heartbeat interval to determine a probability of having arrhythmia for the person; generate an alert to the user interface, if the probability exceeds a predetermined threshold value, to alert the person to measure the electrocardiogram with the means for measuring an electrocardiogram; analyze the measured electrocardiogram to determine if the probable arrhythmia is confirmed; and indicate the confirmed arrhythmia to the person via the user interface.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: June 27, 2023
    Assignee: Heart2Save Oy
    Inventors: Helena Jäntti, Mika Tarvainen, Jukka Lipponen
  • Patent number: 11672437
    Abstract: Provided herein are methods and devices configured to detect the heart rate of a user. The method includes receiving at least one input signal, separating the input signal into signal components, receiving a motion signal from the user, and applying a Bayesian filter to the signal components and the motion signal to estimate the heart rate of the user. The method further includes calculating a combination of at least two reflected light signals from at least two different wavelengths. The device includes a photodetector configured to detect at least one reflected light signal resulting from the emitted at least two different wavelengths and a motion detector for detecting a motion signal. The device also includes a processing component configured to calculate a combination of the reflected light signals, separate the combination of detected light signals into signal components, and apply a Bayesian filter to the signals.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: June 13, 2023
    Assignee: Happy Health, Inc.
    Inventors: Byron Olson, Paulo E. Xavier Da Silveira, Nithin O. Rajan, Dustin M. Freckleton
  • Patent number: 11647924
    Abstract: Apparatus and methods provide wireless, disposable, continuous pulse oximeter sensor technology, useful and beneficial for a number of applications including relatively extended periods of data collection, and/or packaged in compact and easy-to-use assemblies. Economic fabrication and use provides flexible methodologies that can reduce the overall costs of monitoring and collecting patient's physiological data, and provide relatively greater ease and comfort to the patient. A disposable wireless continuous pulse oximeter sensor has a reduced emitter-detector separation, a low-power frontend, and a low-cost processor that sends waveforms to a host device so that the host can calculate and display the parameters of interest. Complications created by the reduced distance between emitter and detector are minimized by using an emitter-detector assembly with an optically dark background, and a bandage for improved optical compliance.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: May 16, 2023
    Assignee: True Wearables, Inc.
    Inventors: Marcelo Malini Lamego, Tatiana Buticosky Lamego