Cardiovascular Testing Patents (Class 600/479)
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Publication number: 20150105666Abstract: A PPG or other cardiac signal is analysed by calculating its amplitude in a narrow frequency range around the estimated heart rate or a harmonic of the heart rate. Cardiac signals from a patient in different states, e.g., exercise and non-exercise or limb lowered and limb raised can be analysed and the amplitude in the narrow range compared to determine various vascular conditions such as peripheral arterial disease.Type: ApplicationFiled: May 28, 2013Publication date: April 16, 2015Inventor: Iain Guy David Strachan
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Publication number: 20150105670Abstract: The present invention relates to the measurement of vital signs such as a respiratory rate or a heart rate. In particular, a system (1) for determining a vital sign of a subject (100), comprising an imaging unit (2) for obtaining video data of the subject, a marker (10, 20, 60, 61) directly or indirectly attached to a body of the subject, wherein the marker comprises a graphical pattern (11, 21), an image processing unit (3) for detecting said marker in said video data, and an analysis unit (4) adapted to extract a vital sign parameter related to the vital sign of the subject from said video data and to determine the vital sign from said vital sign parameter. Further aspects of the invention relate to a device and a method for determining a vital sign of a subject and a computer program for carrying out said method.Type: ApplicationFiled: June 11, 2013Publication date: April 16, 2015Applicant: KONINKLIJKE PHILIPS N.V.Inventors: Erik Bresch, Jens Muehlsteff, Timo Tigges, Alexander Dubielczyk, Caifeng Shan
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Publication number: 20150105671Abstract: A biological information measurement device includes a device main body and a band configured to secure the device to a body part of a user. The device main body contacts the user's skin to thereby acquire biological information about the user, and presents a non-rectangular parallelogram surface in plan view. The parallelogram surface has two longitudinal edges disposed along a longitudinal direction, and two oblique edges disposed along an oblique direction that is transverse to, but not perpendicular to, the longitudinal direction. The band is attached to the oblique edges of the device main body, and generally extends in the longitudinal direction.Type: ApplicationFiled: October 9, 2014Publication date: April 16, 2015Inventors: Junya SHIBUYA, Yoshihiro Hidai, Shigemitsu Tanaka
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Publication number: 20150099949Abstract: Methods and systems are presented for displaying physiological information with a physiological monitor. A physiological parameter, for example oxygen saturation, is computed from a received physiological signal, for example a PPG signal. At least one metric associated with the received physiological signal is determined, for example a statistical measure of uncertainty associated with the determined physiological parameter. Display parameters are determined, for example a width parameter, based on the metrics and a trace of the computed physiological parameter for a subject is displayed. In some embodiments, the width of the displayed trace may be varied based on the width parameter. In some embodiments, additional or alternative characteristics of the displayed trace may be varied based on respective display parameters.Type: ApplicationFiled: October 3, 2014Publication date: April 9, 2015Inventor: James Wallace
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Publication number: 20150099985Abstract: A physiological signal measurement apparatus is capable of automatically adjusting a measure position and suitable for installed on a support element to measure a physiological signal of a user. The physiological signal measurement apparatus includes a movable element, a physiological signal sensing element, a pressure sensing unit and a microcontroller unit. The movable element has a first pressure. The user exerts a second pressure on the physiological signal sensing element, and exerts a third pressure on the support element. The pressure sensing unit senses the first pressure, the second pressure and the third pressure to generate a first pressure signal, a second pressure signal and a third pressure signal. The microcontroller unit receives the physiological signals and the pressure signals, and controls the movable element by the pressure signals and the physiological signals, in order to increase the quality of signal measurement.Type: ApplicationFiled: June 23, 2014Publication date: April 9, 2015Inventors: Chong-Rong WU, Yuan-Hsiang LIN
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Publication number: 20150099987Abstract: A system and method for evaluating heart rate variability for mental state analysis is disclosed. Video of an individual is captured while the individual consumes and interacts with media. The video is analyzed to determine heart rate information with heart rate variability (HRV) being calculated and being understood to be in response to stimuli from the media. The analysis of heart rate variability is based upon a sympathovagal balance derived from a ratio of low frequency heart rate values to high frequency heart rate values. Heart rate variability is analyzed to determine changes in an individual's mental state related to the stimuli. Heart rate variability is determined and thereby mental state analysis is performed to evaluate media.Type: ApplicationFiled: December 13, 2014Publication date: April 9, 2015Inventors: Viprali Bhatkar, Rana el Kaliouby, Youssef Kashef, Ahmed Adel Osman
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Publication number: 20150099986Abstract: A mask configured to be attached to the face of a subject includes a wall section that defines an internal space and covers at least a portion of a nose and a mouth of the subject, an expired gas introduction section that is disposed in the internal space and introduce the subject's expired gas, and a communication section defining a communication channel through which the subject's expired gas introduced from the expired gas introduction section is introduced into an expired gas concentration detection sensor. The position of the expired gas introduction section in the internal space is variable.Type: ApplicationFiled: October 3, 2014Publication date: April 9, 2015Inventor: Masayuki Inoue
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Publication number: 20150099943Abstract: A wearable physiological sensing device with optical pathways is described. The wearable physiological sensing device may include at least one light source; a first light pipe coupled with the at least one light source, the first light pipe at least partially circumscribing an extremity of a patient, and including at least one aperture for radiating light from the light source into the extremity. The wearable physiological sensing device may also include a second light pipe including at least one aperture for receiving the light radiated through the extremity, the second light pipe at least partially circumscribing the extremity of the patient, and an optical receiver coupled with the second light pipe configured to receive the light and output one or more signals representative of the received light.Type: ApplicationFiled: October 2, 2014Publication date: April 9, 2015Inventor: BRIAN KEITH RUSSELL
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Patent number: 9002440Abstract: A computer-implemented method for characterizing circulatory blood volume and autoregulatory compensatory mechanisms to maintain circulatory blood volume is disclosed. A biological signal that emulates the arterial pulse wave is collected from a sensor. Three derived parameters are extrapolated from the biological signal. The first parameter, circulatory stress, reflects of the changes of the heart rate frequency. The second, circulatory blood volume, reflects the changes in the frequency strength of the heart rate frequency. The third, Pulse Volume Alteration (PVA) Index is a ratio of the sum of the strengths of the heart rate frequency harmonics to the strength of the heart rate frequency of the unprocessed biological signal. Each parameter is compared to a threshold value and assessed to determine an adequacy of circulatory blood volume and an appropriateness of the autoregulatory mechanisms used to maintain circulatory blood volume adequacy.Type: GrantFiled: March 15, 2013Date of Patent: April 7, 2015Assignee: Intelomed, Inc.Inventors: Jan K. Berkow, Anne M. Brumfield
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Publication number: 20150094577Abstract: Electrophysiology mapping and visualization systems are described herein where such devices may be used to visualize tissue regions as well as map the electrophysiological activity of the tissue. Such a system may include a deployment catheter and an attached hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. A position of the catheter and/or hood may be tracked and the hood may also be used to detect the electrophysiological activity of the visualized tissue for mapping.Type: ApplicationFiled: December 10, 2014Publication date: April 2, 2015Inventors: Vahid Saadat, Ruey-Feng Peh, Edmund A. Tam
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Publication number: 20150088431Abstract: Implementations disclosed herein provide a monitoring technology. In one implementation, a monitoring system measures whole body biometric levels by analysis of changes in vascular volume caused by pulsatile pressure waves and in tissue volume in response to the pulsatile pressure. The monitoring system includes a monitoring device, which uses a light-based measurement technique to measure biometric levels during different activities and at rest. A light source operatively connected to a light sensor, transmits light, reflectively or transmissively, through tissue. The light sensor detects absorption of the light. Based on wavelength measurements of the detected light, the monitoring device produces a PPG waveform representing characteristic effects of certain physiological parameters. In one implementation, operating contexts are sensed in a monitoring device. A monitoring profile is selected based on the sensed operating contexts.Type: ApplicationFiled: September 19, 2014Publication date: March 26, 2015Inventors: Ronald Podhajsky, Arlen J. Reschke
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Publication number: 20150088002Abstract: Implementations disclosed herein provide a hydration monitoring technology. In one implementation, a hydration monitoring system measures whole body hydration levels by analysis of changes in vascular volume caused by pulsatile pressure waves and in tissue volume in response to the pulsatile pressure. The hydration monitoring system includes a hydration monitoring device, which uses a light-based measurement technique to measure hydration levels and heart rate during different activities and at rest. In one implementation, a light source operatively connected to a light sensor, transmits light, reflectively or transmissively, through tissue. The light sensor detects absorption of the light. Based on wavelength measurements of the detected light, the hydration monitoring device produces a PPG waveform representing characteristic effects of hydration. Based on analysis of the PPG waveform, the hydration monitoring device determines a hydration metric representative of hydration levels in the body.Type: ApplicationFiled: September 19, 2014Publication date: March 26, 2015Inventors: Ronald Podhajsky, Arlen J. Reschke
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Publication number: 20150088003Abstract: Implementations disclosed herein provide a monitoring technology. In one implementation, a monitoring system measures whole body biometric levels by analysis of changes in vascular volume caused by pulsatile pressure waves and in tissue volume in response to the pulsatile pressure. The monitoring system includes a monitoring device, which uses a light-based measurement technique to measure biometric levels during different activities and at rest. A light source operatively connected to a light sensor, transmits light, reflectively or transmissively, through tissue. The light sensor detects absorption of the light. Based on wavelength measurements of the detected light, the monitoring device produces a PPG waveform representing characteristic effects of certain physiological parameters. PPG pulse data is selected that satisfies a data integrity condition. Based on analysis of the selected PPG pulse data, the monitoring device computes a biometric.Type: ApplicationFiled: September 19, 2014Publication date: March 26, 2015Inventors: Ronald Podhajsky, Arlen J. Reschke
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Publication number: 20150087928Abstract: Implementations disclosed herein provide a hydration monitoring technology. In one implementation, a hydration monitoring device measures whole body hydration levels by analysis of changes in vascular volume caused by pulsatile pressure waves and in tissue volume in response to the pulsatile pressure. The hydration monitoring device uses a light-based measurement technique to transmits light, reflectively or transmissively, through tissue. Based on wavelength measurements of the detected light, the hydration monitoring device produces a PPG waveform representing characteristic effects of hydration. The hydration monitoring device monitors operating condition signals associated with the hydration monitoring device. By monitoring operating condition signals, the hydration monitoring device determines whether the operating condition signals satisfy an analysis condition, and modifies the optical sensing operations.Type: ApplicationFiled: September 19, 2014Publication date: March 26, 2015Inventors: Ronald Podhajsky, Arlen J. Reschke
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Publication number: 20150080745Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.Type: ApplicationFiled: July 3, 2014Publication date: March 19, 2015Applicant: ACCUVEIN INC.Inventors: Fred Wood, Ron Goldman, Stephen P. Conlon, Vincent Luciano
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Publication number: 20150080746Abstract: Described herein are methods for determining a target musculoskeletal activity cycle (MSKC) to cardiac cycle (CC) timing relationship. The method may include detecting a first characteristic of a signal responsive to a CC timing of a user that repeats at a frequency that corresponds to a heart rate of the user; detecting a second characteristic of a signal responsive to a rhythmic musculoskeletal cycle activity (MSKC) timing of the user that repeats at a frequency that corresponds to the MSKC rate of the user; determining a value representative of an actual timing relationship between the first characteristic and the second characteristic; detecting a third characteristic of a signal corresponding to a physiological metric that varies with the actual timing relationship between the first and second characteristics; and determining a target value representative of a preferred timing relationship between the first and second characteristics.Type: ApplicationFiled: November 25, 2014Publication date: March 19, 2015Inventors: Jeffery L. Bleich, Paul D. Mannheimer
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Publication number: 20150080742Abstract: An OCI medical device includes a coherent light source, a light sensor, a first processing unit adapted to calculate OCI Data from the light sensor, a control unit which allows taking or loading of at least one Reference OCI Value, a second processing unit adapted to calculate the Intra-Individual Relative Assessment of the OCI Data of an Imaging Zone and the at least one OCI Reference Value, and display means adapted to show at least one Relative OCI Value. Uses and a method for assessing the blood flow of a body region use OCI imaging and include an Intra-Individual Relative Assessment between OCI Data of the Imaging Zone and at least one Reference OCI Value.Type: ApplicationFiled: April 25, 2013Publication date: March 19, 2015Applicant: AIMAGO S.A.Inventors: Marc Andre, Michael Friedrich, Tyler Thacher, Andrey Naumenko, Romain Farkas
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Publication number: 20150073271Abstract: Disclosed herein are systems and methods for revascularization assessment. The methods can in some cases include one or more of the steps of measuring blood perfusion as a function of time to obtain time series data, mathematically transforming the time series data into a power spectrum, calculating at least one parameter of the power spectrum within a specific frequency range, and using the at least one calculated parameter as a discriminator for the first population and the second population.Type: ApplicationFiled: August 14, 2014Publication date: March 12, 2015Inventors: Kijoon Lee, Renzhe Bi, Jing Dong, Justin Dauwels
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Patent number: 8977347Abstract: What is disclosed is a video-based system and method for estimating heart rate variability from time-series signals generated from video images captured of a subject of interest being monitored for cardiac function. In a manner more fully disclosed herein, low frequency and high frequency components are extracted from a time-series signal obtained by processing a video of the subject being monitored. A ratio of the low and high frequency of the integrated power spectrum within these components is computed. Analysis of the dynamics of this ratio over time is used to estimate heart rate variability. The teachings hereof can be used in a continuous monitoring mode with a relatively high degree of measurement accuracy and find their uses in a variety of diverse applications such as, for instance, emergency rooms, cardiac intensive care units, neonatal intensive care units, and various telemedicine applications.Type: GrantFiled: June 25, 2012Date of Patent: March 10, 2015Assignee: Xerox CorporationInventors: Lalit Keshav Mestha, Survi Kyal, Beilei Xu, Himanshu J. Madhu
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Patent number: 8977348Abstract: A system is provided including a thoracic bio-impedance or bio-reactance (TBIR) analysis module, a photoplethysmograph (PPG) analysis module, and a cardiac output module. The TBIR module is configured to obtain TBIR information from a TBIR detector, and the PPG analysis module is configured to obtain PPG information from a PPG detector. The cardiac output module is configured to determine the cardiac output of a patient using the TBIR information and the PPG information.Type: GrantFiled: December 21, 2012Date of Patent: March 10, 2015Assignee: Covidien LPInventors: Mark Su, Lockett Wood
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Publication number: 20150065891Abstract: Method of determining atrial fibrillation including determining if a patient's pulse beats form an irregular pattern and only if so, indicating the presence of an irregular pulse to the patient and obtaining an electrocardiogram for determining atrial fibrillation. Initially, a pulse is detected at regular time intervals of a first appendage of the patient when motionless using a pulse detector secured to the first appendage and pulse rhythms from a succession of time intervals are detected each corresponding to a respective interval of time between successive pulse beats of a sequence of the pulse beats. Then, an electrically conductive unit is attached to a second appendage of the patient, or a wearable electrocardiogram is attached to the patient, and electrocardiograms signals are detected simultaneously with pulse rhythms while the first appendage is motionless and analyzed to determine whether, in combination, they are indicative of atrial fibrillation.Type: ApplicationFiled: August 26, 2014Publication date: March 5, 2015Inventor: Joseph Wiesel
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Publication number: 20150065888Abstract: Disclosed herein is a method for obtaining a value of at least one vasodilation parameter representing the cutaneous local thermal hyperemia response of a subject. The temperature of a sampling site is raised from a first temperature to a second temperature and maintained for an initial heating period, and an initial maximum red blood cell flux (RBCF) of the sampling site and a mean arterial pressure of the subject is obtained. An initial maximum cutaneous vascular conductance (CVC1,max) is calculated by dividing the initial maximum RBCF by the mean arterial pressure. The CVC1, max or at least one other parameter derived therefrom is used as the vasodilation parameter.Type: ApplicationFiled: March 26, 2013Publication date: March 5, 2015Inventors: Chung-Shin Huang, Yuan-Feen Tsai, Shwu-Fen Wang
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Publication number: 20150065830Abstract: In accordance with one aspect of the present technique, a method is disclosed. The method includes receiving continuous photoplethysmographic (PPG) data of a subject from a sensor and calculating a continuous blood characteristic (BC) based on the continuous PPG data. The method also includes calculating a first quality metric of the continuous PPG data based on a sequence of the continuous BC. The method further determines whether the first quality metric satisfies a stability criterion and sending a first notification to the sensor in response to determining that the first quality metric satisfies the stability criterion. The first notification instructs the sensor to collect compressed PPG data of the subject.Type: ApplicationFiled: August 30, 2013Publication date: March 5, 2015Applicant: General Electric CompanyInventors: Jason Harris Karp, Bahman Ebrahimi Kashef, SM Shajedul Hasan
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Publication number: 20150065890Abstract: An optical biometric system (1) is characterized by being provided with: a first received light amount information acquisition unit (25) which acquires skin blood flow data relating to a skin blood flow in a wide range of the scalp of a subject by controlling the transmission/reception of light to/from a light transmission/reception unit (30) using a wide-range control table; and a selection control table creation unit (24) which causes a storage unit (23) to store a selection control table for acquiring X pieces of first received light amount information (?A1) selected from among N pieces of first received light amount information (?A1), and in that when acquiring multiple pieces of measurement data relating to the brain activity in a predetermined range of the brain of the subject by controlling the transmission/reception of light to/from the light transmission/reception unit (30) using a control table, a light transmission/reception control unit (21) acquires skin blood flow data relating to a skin blood fType: ApplicationFiled: May 11, 2012Publication date: March 5, 2015Applicant: SHIMADZU CORPORATIONInventors: Akihiro Ishikawa, Yoshihiro Inoue, Takashi Amita, Satoru Kohno, Haruhide Udagawa, Yoshinori Masuda
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Publication number: 20150065892Abstract: A pulse wave measuring device includes: a connector that is disposed on a main unit; an external sensor that includes an external light-emitting module radiating light to a human body to be measured and an external light-receiving module receiving at least one of reflected light and transmitted light originating from the external light-emitting module and the human body so as to measure a pulse wave; an first controller that switches the external light-emitting module ON and OFF; an second controller that switches the external light-receiving module ON and OFF; and an external sensor connection determination section that determines a connection between the external sensor and the connector in accordance with a transient response of the external light-receiving module, wherein, after the external sensor connection determination section determines that the external sensor is connected to the connector, a measurement of the pulse wave by using the external sensor is started.Type: ApplicationFiled: October 14, 2014Publication date: March 5, 2015Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Kazushige OUCHI, Takuji SUZUKI, Kenichi KAMEYAMA
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Publication number: 20150065889Abstract: A Photoplethysmography-based sensor for measuring heart rate is provided herein. The sensor may include a first light source and a second light source configured to illuminate a body tissue by a first light and a second light respectively; and a first and a second light detectors, each configured to detect light comprising portions of said first light and of said second light, transferred through the body tissue; and a processor with an analog measurement part configured to: receive light intensity readings of at least a portion of light as sensed by each one of both sensors and coming from each one of both sources; and calculate a measure of tissue absorption based on ratios of light portions transmitted by each one of both sources and measured by each one of both detectors.Type: ApplicationFiled: September 2, 2013Publication date: March 5, 2015Applicant: Life Beam Technologies Ltd.Inventors: Yosef GANDELMAN, Zvi Orron, Yoav Aminov, Omri Yoffe, Roy Rozenman, Jonathan Aprasoff
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Patent number: 8971985Abstract: What is disclosed is a system and method for estimating minute ventilation by analyzing distortions in reflections of structured illumination patterns captured in a video of a thoracic region of a subject of interest being monitored for respiratory function. Measurement readings can be acquired in a few seconds under a diverse set of lighting conditions and provide a non-contact approach to patient respiratory function that is particularly useful for infant care in an intensive care unit (ICU), sleep studies, and can aid in the early detection of sudden deterioration of physiological conditions due to detectable changes in chest volume. The systems and methods disclosed herein provide an effective tool for non-contact minute ventilation estimation and respiratory function analysis.Type: GrantFiled: June 1, 2012Date of Patent: March 3, 2015Assignee: Xerox CorporationInventors: Edgar A. Bernal, Lalit Keshav Mestha, Beilei Xu
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Publication number: 20150057508Abstract: A physiological information measuring apparatus includes a first detection unit, having a first light emitting unit and a first light receiving unit, separated from one another by a first distance. A second detection unit of the physiological information measuring apparatus has a second light emitting unit and a second light receiving unit, separated from one another by a second, different distance. Alternatively, the second detection unit shares the first light emitting unit with the first detection unit and has a second light receiving unit. Alternatively, the second detection unit shares the first light receiving unit with the first detection unit and has a second light emitting unit. A measuring unit of the physiological information measuring apparatus measures the physiological information of a user based on light received by the light receiving unit or light receiving units.Type: ApplicationFiled: August 19, 2014Publication date: February 26, 2015Inventor: Atsushi NARUSAWA
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Patent number: 8965472Abstract: A near infrared spectrophotometric (NIRS) sensor assembly for non-invasive monitoring of blood oxygenation levels in a subject's body is provided that includes a pad, at least one light source, a near light detector, a far light detector, and a cover. The light source is operative to emit near infrared light signals of a plurality of different wavelengths. The near light detector is separated from the light source by a first distance that is great enough to position the first light detector outside of an optical shunt field extending out from the light source. The far light detector is substantially linearly aligned with the near light detector and light source, and is separated from the near light detector by a second distance, wherein the second distance is greater than the first distance.Type: GrantFiled: October 18, 2006Date of Patent: February 24, 2015Inventor: Paul Benni
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Publication number: 20150051452Abstract: Exemplary method, computer-readable medium and system can be provided for generating at least one information associated with at least one signal and/or data received from at least one structure. For example, it is possible to determine at least one basis based on a combination of a plurality of portions of the signal(s) and/or the data. It is also possible to generate the information(s) as a function of the basis.Type: ApplicationFiled: August 25, 2014Publication date: February 19, 2015Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKInventor: EDWARD J. CIACCIO
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Publication number: 20150051461Abstract: What is disclosed is a system and method for performing a medical diagnosis for a subject of interest using a RGB video camera and a spot radiometer in a non-contact, remote sensing environment. In one embodiment, video images are captured using a RGB video camera in real-time of a subject of interest for medical diagnostic purposes. The video images are analyzed to identify a region of exposed skin for which measurements are desired to be obtained. A relative position of a spot radiometer is then adjusted such that the spot radiometer can measure incident radiation at a desired wavelength range from the identified region of exposed skin. The measurements are then used to perform a medical diagnosis for the subject. Various embodiments are disclosed.Type: ApplicationFiled: August 16, 2013Publication date: February 19, 2015Applicant: XEROX CORPORATIONInventors: Edul N. DALAL, Wencheng WU, Lalit Keshav MESTHA
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Publication number: 20150045639Abstract: A biological information detector includes a wristband, a light-emitting part, a reflecting part, a light-receiving part, a protecting part, an acceleration sensor and a processing part. The wristband is adapted to be attached to a body of a user. The light-emitting part is configured to emit green light. The reflecting part is configured to reflect the light emitted by the light-emitting part. The light-receiving part is configured to receive reflected light reflected at a detection site of the body of the user. The protecting part is configured to protect the light-emitting part, the protecting part having a contact surface configured to contact with the detection site. The acceleration sensor is configured to detect acceleration generated by the user. The processing part is configured to process a light reception signal outputted from the light-receiving part.Type: ApplicationFiled: October 22, 2014Publication date: February 12, 2015Inventors: Hideto YAMASHITA, Yoshitaka IIJIMA
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Publication number: 20150045633Abstract: A system and method for hemodynamic dysfunction detection may include at least one sensor configured to received one or more signals from a patient, a computing device in data communication with the at least one sensor, a computer-readable storage medium in communication with the computing device, an input device, and an output device. The system may include computer readable instructions to cause the system to receive at least one signal in the time domain from the sensor, determine at least one metric in the frequency domain from the at least one signal in the time domain, and determine the cardiovascular state of the patient from a combination of the at least one metric in the frequency domain and information contained in at least one database of cardiovascular states. The system may also notify a user of a immanent patient cardiovascular event and recommend one or more interventions to mitigate it.Type: ApplicationFiled: August 12, 2014Publication date: February 12, 2015Inventors: Jan K. BERKOW, Anne M. BRUMFIELD
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Patent number: 8954135Abstract: The present inventions, in one aspect, are directed to portable biometric monitoring device including a housing having a physical size and shape that is adapted to couple to the user's body, at least one band to secure the monitoring device to the user, a physiological sensor, disposed in the housing, to generate data which is representative of a physiological condition of the user data. The physiological sensor may include a light source to generate and output light having at least a first wavelength, and a photodetector to detect scattered light (e.g., from the user). A light pipe is disposed in the housing and optically coupled to the light source directs/transmits light therefrom along a predetermined path to an outer surface of the housing. Processing circuitry calculates a heart rate of the user using data which is representative of the scattered light.Type: GrantFiled: June 24, 2013Date of Patent: February 10, 2015Assignee: Fitbit, Inc.Inventors: Shelten Gee Jao Yuen, Mark Manuel Martinez, Andrew Cole Axley, Eric Nathan Friedman, James Park
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Publication number: 20150038853Abstract: There is provided a wearable item configured to be placed at least partially against a skin of a person; and an optically sensitive detector mounted to the wearable item and configured to detect optical signals reflected from the skin of the person, wherein the detected optical signals represent a relative motion between the wearable item and the skin of the person and wherein the optically sensitive detector is mounted to the wearable item such that there is a predetermined space between the optically sensitive detector and the skin of the person.Type: ApplicationFiled: February 25, 2013Publication date: February 5, 2015Inventor: Elias Pekonen
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Publication number: 20150038854Abstract: Systems and methods for detecting a worsening of patient's heart failure condition based, at least in part, on an increasing trend in a representative rapid shallow breathing index (RSBI) value over multiple days. The RSBI value may be a minimum RSBI, and more particularly may be a minimum RSBI value determined for an afternoon portion of each of the multiple days. The minimum RSBI value measured during an afternoon portion of the day may be more sensitive to changes in a patient's respiration, particularly when a patient is expected to be more active, and thus, may more readily exhibit an increasing trend when patient's heart failure is in decline.Type: ApplicationFiled: August 4, 2014Publication date: February 5, 2015Inventors: Yi Zhang, Viktoria A. Averina, Kenneth C. Beck, Pramodsingh Thakur, Ramesh Wariar
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Publication number: 20150031971Abstract: A physiological monitoring system may receive a sensor signal from a physiological sensor. The system may generate an estimate of the sensor signal based on, for example, prior received signals. The estimate signal may be subtracted from the sensor signal using a transimpedance amplifier to generate a difference signal. A gain and/or offset may be applied to the difference signal by the amplifier. The amplified difference signal may be digitized and combined with the estimate signal to generate a high resolution digital representation of the sensor signal. Physiological information such as blood oxygen saturation, pulse rate, respiration rate, respiration effort, blood pressure, hemoglobin concentration, any other suitable physiological parameters, or any combination thereof, may be determined using the digitized sensor signal.Type: ApplicationFiled: July 26, 2013Publication date: January 29, 2015Applicant: Covidien LPInventors: Daniel Lisogurski, Christopher Meehan
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Publication number: 20150031965Abstract: A method for monitoring physiological parameters associated with a subject using a hand held device is described herein. In an implementation, the method includes obtaining a plurality of sample photoplethysmographic (PPG) features associated with a sample subject, from a video of a body part of the sample subject. From among the plurality of sample PPG features, at least one relevant sample PPG feature associated with the physiological parameter, is selected based on a ground truth value of the physiological parameter for the subject. Further, based on the at least one relevant sample PPG feature and the ground truth value of the physiological parameter, a mathematical model indicative of a correlation between the relevant sample PPG feature and the physiological parameter, is determined. The mathematical model can be deployed for monitoring the physiological parameter in real time.Type: ApplicationFiled: July 28, 2014Publication date: January 29, 2015Inventors: Aishwarya Visvanathan, Arpan Pal, Anirban Dutta Choudhury, Tanushyam Chattopadhyay, Anurag Kumar, Rohan Banerjee, Aniruddha Sinha
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Publication number: 20150025394Abstract: Some embodiments provide a wearable fitness monitoring device including a motion sensor and a photoplethysmographic (PPG) sensor. The PPG sensor includes (i) a periodic light source, (ii) a photo detector, and (iii) circuitry determining a user's heart rate from an output of the photo detector. Some embodiments provide methods for operating a heart rate monitor of a wearable fitness monitoring device to measure one or more characteristics of a heartbeat waveform. Some embodiments provide methods for operating the wearable fitness monitoring device in a low power state when the device determines that the device is not worn by a user. Some embodiments provide methods for operating the wearable fitness monitoring device in a normal power state when the device determines that the device is worn by a user. Some embodiments provide methods for using response characteristics of the user's skin to adjust a gain and/or light emission intensity of the heart rate monitor.Type: ApplicationFiled: October 6, 2014Publication date: January 22, 2015Inventors: Jung Ook Hong, Shelten Gee Jao Yuen
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Publication number: 20150025393Abstract: Some embodiments provide a wearable fitness monitoring device including a motion sensor and a photoplethysmographic (PPG) sensor. The PPG sensor includes (i) a periodic light source, (ii) a photo detector, and (iii) circuitry determining a user's heart rate from an output of the photo detector. Some embodiments provide methods for operating a heart rate monitor of a wearable fitness monitoring device to measure one or more characteristics of a heartbeat waveform. Some embodiments provide methods for operating the wearable fitness monitoring device in a low power state when the device determines that the device is not worn by a user. Some embodiments provide methods for operating the wearable fitness monitoring device in a normal power state when the device determines that the device is worn by a user.Type: ApplicationFiled: October 6, 2014Publication date: January 22, 2015Inventors: Jung Ook Hong, Shelten Gee Jao Yuen
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Publication number: 20150025334Abstract: The present disclosure provides a method and system for stimulating and monitoring intensity of pain experienced by one or more users. The method includes measuring the intensity of pain experienced by the one or more users on a pre-determined scale and augmented chart or physician's personal assessment using a plurality of one or more bio-markers, determining co-relation between the plurality of one or more bio-markers and the intensity of pain experienced by the one or more users, refining the co-relation between the plurality of one or more bio-markers and the intensity of pain experienced by the one or more users by learning from responses of one or more similar users, generating a pain profile for each of the one or more users and utilizing the learned information and the generated profile for monitoring, evaluating and treating the one or more users.Type: ApplicationFiled: September 9, 2014Publication date: January 22, 2015Inventor: LAKSHYA JAIN
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Publication number: 20150018665Abstract: According to some aspects, the invention relates to methods and compositions for evaluation of hemodynamic responses (e.g., using molecular imaging) with high sensitivity.Type: ApplicationFiled: July 15, 2014Publication date: January 15, 2015Applicant: Massachusetts Institute of TechnologyInventors: Alan Pradip Jasanoff, Adrian Lukas Slusarczyk, Mitul Desai, Mariya Barch, Gil G. Westmeyer
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Publication number: 20150018693Abstract: What is disclosed is a method for monitoring a subject for cardiac arrhythmia such as atrial fibrillation using an apparatus that can be comfortably worn by the subject around an area of exposed skin where a photoplethysmographic (PPG) signal can be registered. In one embodiment, the apparatus is a reflective or transmissive wrist-worn device with emitter/detector pairs fixed to an inner side of a band with at least one illuminator emitting source light at a specified wavelength band. The illuminator is paired to a respective photodetector comprising one or more sensors that are sensitive to a wavelength band of its paired illuminator. The photodetector measures intensity of sensed light emitted by a respective illuminator. The signal obtained by the sensors comprises a continuous PPG signal. The continuous PPG signal analyzed for peak-to-peak pulse points from which the existence of cardiac arrhythmia such as atrial fibrillation event can be determined.Type: ApplicationFiled: July 9, 2013Publication date: January 15, 2015Inventors: Lalit Keshav MESTHA, Survi KYAL, Barry P. MANDEL, Peter Johan NYSTROM
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Publication number: 20150011898Abstract: Methods and apparatus disclosed herein use a filtering technique to improve the accuracy of the results achieved when processing data provided by a physiological sensor. The disclosed filtering technique corrects many of the accuracy problems associated with physiological sensors, particularly PPG sensors. Broadly, the filtering technique adjusts a current filtered estimate of a physiological metric as a function of a rate limit based on a comparison between an instantaneous estimate of the physiological metric and the current filtered estimate.Type: ApplicationFiled: December 24, 2012Publication date: January 8, 2015Inventor: Eric Douglas Romesburg
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Publication number: 20150011845Abstract: A system comprising a biometric monitoring device including a housing including a platform to receive at least one foot of the user, a body weight sensor to generate body weight data, processing circuitry to calculate user weight data which corresponds to the user's weight, using the body weight data, and communication circuitry to: (a) receive user identification data which identifies the user or a portable activity monitoring device, and (b) transmit the user weight data to data storage associated with the user identification data. The system further includes the portable activity monitoring device including a housing having a physical size and shape that is adapted to couple to the user's body, a sensor to generate sensor data, and communication circuitry to receive physiologic data which is based on the user weight data, and processing circuitry to calculate activity data using the sensor data and physiologic data.Type: ApplicationFiled: September 22, 2014Publication date: January 8, 2015Inventors: Shelten Gee Jao Yuen, Eric Nathan Friedman, James Park
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Patent number: 8929974Abstract: In a system and a method for examining an object containing a fluid liquid, the object is illuminated with measuring light and images are temporarily shortly subsequently recorded. The images are evaluated per pixel to determine perfusion data from a high frequency portion above 1 kHz and to determine further information about properties of the object from a low frequency portion below 100 Hz, such as a degree of oxygenation of hemoglobin, a concentration of hemoglobin or a concentration of ICG. This information determined by evaluation is displayed in a form of an image in superposition with a white light image of the object.Type: GrantFiled: April 8, 2010Date of Patent: January 6, 2015Assignee: Carl Zeiss Meditec AGInventors: Christoph Hauger, Werner Nahm, Theo Lasser, Marcel Leutenegger, Erica Martin-Williams, Antonio Lopez
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Publication number: 20150005593Abstract: A biological information detector includes a light-emitting part, a first connecting pad, a first bonding wire and a light transmission part. The first bonding wire electrically connects the light-emitting part and the first connecting pad. The light transmission part transmits light emitted by the light-emitting part. The light transmission part covers the light-emitting part and the first bonding wire.Type: ApplicationFiled: September 17, 2014Publication date: January 1, 2015Inventors: Yoshitaka IIJIMA, Hideto YAMASHITA, Hideo MIYASAKA
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Publication number: 20150005646Abstract: Heart rates and beat lengths can be extracted from videos by measuring subtle head motion caused by the Newtonian reaction to the influx of blood at each beat. In an embodiment of the present invention, a method tracks features on the head and performs principal component analysis (PCA) to decompose their trajectories into a set of component motions. The method then selects a component that best corresponds to heartbeats based on its temporal frequency spectrum. Finally, the motion projected to this component is analyzed and peaks of the trajectories are identified, which correspond to heartbeats.Type: ApplicationFiled: June 25, 2014Publication date: January 1, 2015Inventors: Guha Balakrishnan, John V. Guttag, Frederic Durand
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Publication number: 20150005645Abstract: Embodiments of a system and method for detecting a leading stroke risk indicator using low-cost, non-contact visual computing methods are generally described herein. In some embodiments, a video camera is arranged to capture a video of a face of a subject to be evaluated for having a stroke risk indicator. A memory is provided for storing data. A processor is coupled to the memory and is arranged to analyze processed image data associated with the video of the face of the subject captured by the video camera. The processor is further arranged to determine whether the processed image data exhibits a leading indicator for carotid artery stenosis.Type: ApplicationFiled: June 26, 2013Publication date: January 1, 2015Inventor: Jonathan Moisant Thompson
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Patent number: 8923950Abstract: A system and method for identifying the location of a medical device within a patient's body may be used to localize the fossa ovalis for trans-septal procedures. The systems and methods measure light reflected by tissues encountered by an optical array. An optical array detects characteristic wavelengths of tissues that are different distances from the optical array. The reflectance of different wavelengths of light at different distances from an optical array may be used to identify the types of tissue encountered, including oxygenated blood in the left atrium as detected from the right atrium through the fossa ovalis.Type: GrantFiled: December 31, 2012Date of Patent: December 30, 2014Assignee: Medtronic Ablation Frontiers LLCInventors: Can Cinbis, Xiaonan Shen, Jonathan L. Kuhn