Visible Light Radiation Patents (Class 600/476)
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Patent number: 11954766Abstract: A method for correcting a shading in a digital image of a three-dimensional observation object obtained by at least one image sensor of an optical observation device is provided. The three-dimensional observation object is illuminated by illumination light and an intensity distribution, and an inhomogeneity in an image brightness is present in the digital image of the three-dimensional observation object. The method includes ascertaining a topography of the three-dimensional observation object, correcting the inhomogeneity in the image brightness of the digital image based on the topography of the three-dimensional observation object and the intensity distribution of the illumination light. In addition, an optical observation system is provided to perform the method.Type: GrantFiled: February 28, 2022Date of Patent: April 9, 2024Assignee: Carl Zeiss Meditec AGInventors: Dominik Scherer, Susanne Kohlhammer, Stefan Saur
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Patent number: 11944390Abstract: Systems and methods are provided in which an intraoperative video feed is augmented with one or more virtual display features based on a detected orientation and position of the tracked medical instrument. In some example embodiments, the virtual display features may be employed to represent, in an augmented video feed, information associated with a previously-detected intraoperative position and orientation of the tracked medical instrument. The virtual display element may be employed, for example, to facilitate the alignment of an untracked medical instrument with a previously determined intraoperative position and orientation of the tracked medical instrument. In other example embodiments, the virtual display element may be dynamically displayed in a fixed spatial relationship relative to the tracked medical instrument.Type: GrantFiled: April 8, 2019Date of Patent: April 2, 2024Assignee: 7D Surgical ULCInventors: Adrian Mariampillai, Victor X. D. Yang, Kenneth Kuei-Ching Lee, Michael K. K. Leung, Beau Anthony Standish
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Patent number: 11937906Abstract: Systems and methods for monitoring blood flow metrics using a patch of a flexible substrate configured to attach to an area of skin over a blood vessel. The patch includes a plurality of light sources arranged on the substrate to form a matrix and a row of photodetectors disposed on the substrate substantially in parallel with the rows of LEDs. The patch includes an optical signal interface configured to drive each light source and to input an intensity signal at one of the photodetectors. The intensity signals are used to determine AC and DC components corresponding to each optical path. AC to DC component ratios are calculated for each optical path and used to determine ratio-of-ratio values. At least a subset of the ratio-of-ratio values are used to determine a biological metric or a cross-sectional area of the blood vessel.Type: GrantFiled: April 11, 2021Date of Patent: March 26, 2024Assignee: Alio, Inc.Inventors: Andrei Afanasiev, Forrest Miller, Francis Honore, Anthony Flannery
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Patent number: 11937899Abstract: An imaging system includes an illuminator for providing illumination on a region of interest, one or more first detectors for detecting reflections of the illumination, and a processing unit. The processing unit is configured to: receive a first image containing the region of interest; determine a first region of high specular reflection in the first image based on the reflections of the illumination on the region of interest; mask the first image by substituting a default color designating masking to alert a user to incomplete image information in the first region of high specular reflection to create a masked first image; and generate a composite image based on the masked first image and a fluorescence image of the region of interest.Type: GrantFiled: September 5, 2019Date of Patent: March 26, 2024Assignee: INTUITIVE SURGICAL OPERATIONS, INC.Inventors: Mahdi Azizian, Jonathan M. Sorger
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Patent number: 11933727Abstract: A computer-implemented system for determining an analyte in milk is provided. The system first causes irradiation of the sample with light in a plurality of discrete spectral bands. The spectral bands can be selected based on phenomenon of specific analytes. The irradiation causes a fluorescent response in the milk, which is received by light sensors and converted into digitized spectral data. The digitized spectral data is then transmitted to a machine learning system which can determine the concentration of analytes and produce an output indicative of said concentration.Type: GrantFiled: February 6, 2023Date of Patent: March 19, 2024Assignee: Labby Inc.Inventors: Anshuman Das, Julia Kang Somerdin
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Patent number: 11925459Abstract: A medical system recommends a posture of a subject during a medical procedure. The medical system includes a processor and an output device. The processor determines suitable postures of the subject during the medical procedure based on at least one of subject information, including information on a posture of the subject obtained upon a predetermined movement by the subject and information on the procedure. The output device presents one or more of the suitable postures determined by the processor as recommended postures.Type: GrantFiled: September 10, 2020Date of Patent: March 12, 2024Assignee: TERUMO KABUSHIKI KAISHAInventors: Yusuke Sekine, Yuki Sakaguchi, Akihiko Tarunaga
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Patent number: 11925413Abstract: A computer-implemented method, a computer program, a system and a method for analyzing a time-velocity curve and calculating based on the time-velocity curve ophthalmic parameters.Type: GrantFiled: November 23, 2021Date of Patent: March 12, 2024Inventor: Arash Ghareh Baghi
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Patent number: 11918351Abstract: A method of non-invasively monitoring hemoglobin concentration includes providing incident light to patient tissue at a first excitation wavelength. The method further includes monitoring a first emission response at a first emission wavelength, wherein the first emission wavelength is selected to correspond with a maximum of the emission response, and monitoring a second emission response at a second emission wavelength, wherein the second emission wavelength is selected to correspond with a minimum of the emission response. A hemoglobin concentration is calculated based on a ratio of the first emission response to the second emission response.Type: GrantFiled: June 21, 2021Date of Patent: March 5, 2024Assignee: Medtronic Monitoring, Inc.Inventor: Rodolphe Katra
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Patent number: 11915413Abstract: An endoscope system includes a light source apparatus, an illumination-light setting section capable of setting, as illumination light for illuminating an object including a biological tissue, first illumination light obtained by combining light in one or more wavelength bands selected from the light in plural wavelength bands and second illumination light obtained by combining light in one or more wavelength bands different from the first illumination light, selected out of the light in the plural wavelength bands, a light-source control section, and an image analyzing section configured to acquire an analysis result related to presence or absence of an abnormal finding. The illumination-light setting section sets, based on the analysis result of the image analyzing section for the first image acquired by the first illumination light, a combination of light in wavelength bands included in the second illumination light to be irradiated next.Type: GrantFiled: October 1, 2020Date of Patent: February 27, 2024Assignee: OLYMPUS CORPORATIONInventor: Kenji Yamazaki
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Patent number: 11900556Abstract: A computer system obtains at least one 3D scan of a body surface; automatically identifies, based on the at least one 3D scan, one or more features (e.g., nose, lips, eyes, eyebrows, cheekbones, or specific portions thereof, or other features) of the body surface; and generates a digital 3D model of the body surface. The digital 3D model includes the identified features of the human body surface. In an embodiment, the step of generating of the digital 3D model is based on the at least one 3D scan and the identified features of the body surface. In an embodiment, the digital 3D model comprises a 3D mesh file. The digital 3D model can be used in various ways. For example, output of a manufacturing process (e.g., a 3D printed item, a cosmetics product, a personal care product) can be based on the digital 3D model.Type: GrantFiled: June 30, 2021Date of Patent: February 13, 2024Assignee: L'OrealInventors: David B. Kosecoff, Aldina Suwanto, Grégoire Charraud
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Patent number: 11883132Abstract: A system for the optical measurement of pH includes a light emitter to emit an excitation light, and a detector coupled to receive florescence light produced by a compound in a mouth of a patient in response to the excitation light. A controller is coupled to the detector, and the controller includes logic that when executed by the controller, causes the system to perform operations. The operations may include emitting the excitation light from the light emitter; measuring an intensity of the florescence light emitted from a surface of individual teeth in a plurality of teeth in the mouth; and determining, based on the intensity of the florescence light, one or more locations on the individual teeth likely to develop demineralization.Type: GrantFiled: October 27, 2017Date of Patent: January 30, 2024Assignee: University of WashingtonInventors: Eric J. Seibel, Yuanzheng Gong, Zheng Xu, Jeffrey S. McLean, Yaxuan Zhou
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Patent number: 11885745Abstract: Embodiments disclosed include methods and apparatus for Fluorescent Enhanced Photothermal Infrared (FE-PTIR) spectroscopy and chemical imaging, which enables high sensitivity and high spatial resolution measurements of IR absorption with simultaneous confocal fluorescence imaging. In various embodiments, the FE-PTIR technique utilizes combined/simultaneous OPTIR and fluorescence imaging that provides significant improvements and benefits compared to previous work by simultaneous detection of both IR absorption and confocal fluorescence using the same optical detector at the same time.Type: GrantFiled: July 25, 2022Date of Patent: January 30, 2024Assignee: Photothermal Spectroscopy Corp.Inventor: Craig Prater
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Patent number: 11883130Abstract: A detecting device includes a semiconductor substrate, a first light-emitting section provided in a layered manner at the semiconductor substrate and configured to emit first light having a first wavelength band toward a living body, a second light-emitting section provided at the semiconductor substrate in a layered manner and configured to emit second light having a second wavelength band toward the living body, a first light-receiving section provided at the semiconductor substrate and configured to receive light from the living body based on the first light, a second light-receiving section provided at the semiconductor substrate and configured to receive light from the living body based on the second light, and an optical filter provided at the first light-receiving section and configured to transmit light having the first wavelength band and to attenuate light having the second wavelength band. The second wavelength band is longer than the first wavelength band.Type: GrantFiled: February 23, 2023Date of Patent: January 30, 2024Assignee: SEIKO EPSON CORPORATIONInventors: Tetsuya Yamamoto, Takefumi Fukagawa
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Patent number: 11877826Abstract: In some aspects, the present disclosure provides methods for identifying a disease in an epithelial tissue of a subject. Methods for identifying a disease in an epithelial tissue comprise the generation of a depth profile of the epithelial tissue using signals generated from the tissue by pulses of light directed towards a surface of the epithelial tissue. In some aspects, the present disclosure provides apparatuses consistent with the methods herein.Type: GrantFiled: October 6, 2021Date of Patent: January 23, 2024Assignee: ENSPECTRA HEALTH, INC.Inventors: Gabriel Sanchez, Fred Landavazo, IV, Scott Delp, Kathryn Montgomery
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Patent number: 11882392Abstract: A sound output device according to an exemplary embodiment of the present invention includes: a first housing; a second housing; a substrate; a light emitting unit; and a sound output unit, in which the second housing is connected with the first housing, the substrate is disposed inside the first housing or the second housing, the sound output unit is connected with the substrate, the light emitting unit is connected with the substrate, and the second housing selectively transmits light emitted by the light emitting unit based on a wavelength thereof.Type: GrantFiled: January 17, 2020Date of Patent: January 23, 2024Assignee: IRTRONIX, INC.Inventors: Danny Oh, Chien Nguyen
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Patent number: 11877845Abstract: A method, system, apparatus, and/or device to determine a condition of a user using a spectrometer with a collimator on a glass substrate. The method, system, apparatus, and/or device may include: a band comprising a shape, size, and flexibility designed for attaching the band to a body part of a user; a light source embedded in the band that emits light comprising a constituent wavelength that provides an indication of a feature of the body part; an optical sensor positioned in the band to receive the constituent wavelength; and a glass substrate oriented in the band to receive the light, the glass substrate comprising: an optical filter that comprises a passband to isolate the constituent wavelength from other wavelengths of the light; and a carbon nanotube grid structure comprising walls and through-channels, the carbon nanotube grid structure adhered to the glass substrate.Type: GrantFiled: October 30, 2019Date of Patent: January 23, 2024Assignee: Brigham Young UniversityInventors: Robert Davis, Richard Vanfleet, Nick Morrill, David Miller
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Patent number: 11854288Abstract: To determine the state of a subject person with a simple structure, an image determining device includes: an imaging unit that captures an image from a first direction, the image including the subject person; a first detector that detects size information from the image, the size information being about the subject person in the first direction; a second detector that detects position-related information, the position-related information being different from the information detected by the first detector; and a determining unit that determines the state of the subject person, based on a result of the detection performed by the first detector and a result of the detection performed by the second detector.Type: GrantFiled: June 2, 2021Date of Patent: December 26, 2023Assignee: NIKON CORPORATIONInventors: Tetsuya Yamamoto, Masahiro Nei, Isao Totsuka, Tomoyuki Matsuyama, Masamitsu Yanagihara, Satoshi Hagiwara, Masakazu Sekiguchi
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Patent number: 11839484Abstract: A method for the objective determination of capillary refill behavior on a human body surface in which a spatially and spectrally resolved optical detection is carried out by at least one detector device (1) at a skin surface area (2) having a predefined areal size and outer contour. Subsequently a predefined pressure p constant over the skin surface area (2) is exerted over a predefined time t1; and the pressure effect is ended after expiry of this time t1. The spatially and spectrally resolved optical detection is carried out by the detector device (1) and the respective capillary refill behavior is spatially and temporally determined at a time t2 up to which at least one first threshold value of the measurement values detected simultaneously with spatial resolution has reached the measurement value that had been optically detected before the start of the pressure effect.Type: GrantFiled: May 28, 2021Date of Patent: December 12, 2023Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.Inventors: Uwe Vogel, Bernd Richter, Torsten Richter
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Patent number: 11813482Abstract: The present invention relates to advanced Cherenkov-based imaging systems, tools, and methods of feedback control, temporal control sequence image capture, and quantification in high resolution dose images. In particular, the present invention provides a system and method for simple, accurate, quick, robust, real-time, water-equivalent characterization of beams from LINACs and other systems producing external-therapy radiation for purposes including optimization, commissioning, routine quality auditing, R&D, and manufacture. The present invention also provides a system and method for rapid and economic characterization of complex radiation treatment plans prior to patient exposure. Further, the present invention also provides a system and method of economically detecting Cherenkov radiation emitted by tissue and other media in real-world clinical settings (e.g., settings illuminated by visible light).Type: GrantFiled: January 24, 2022Date of Patent: November 14, 2023Assignee: DoseOptics LLCInventors: Venkataramanan Krishnaswamy, Brian W. Pogue
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Patent number: 11806114Abstract: A system for measuring capillary refill time includes a wearable device and a control unit. The wearable device includes a force sensor to obtain a force signal and an optical sensor to obtain an optical signal. The system ensures that an applied force is acceptable in both magnitude and duration, and that a duration over which the applied force is released or removed is acceptable. These factors can establish that a capillary refill time determined or calculated therein is accurate. The system can also determine the capillary refill time based on the force and optical signals obtained by the force and optical sensors, respectively.Type: GrantFiled: May 29, 2020Date of Patent: November 7, 2023Assignees: ProMedix, Inc., Welch Allyn, Inc., Oregon Health & Science UniversityInventors: David Sheridan, Matthew Lee Hansen, Andrew Kibler, Steven D. Baker, Richard Allen Sunderland, Richard H. Weitzel
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Patent number: 11806085Abstract: Systems for guiding placement of surgical ports on a body include an image capture device configured to capture an image of an operating environment and generate image data based on the captured image, a display device, and a computing device configured to obtain information regarding a location of a surgical site within the body, receive the image data from the image capture device, generate graphical guidance for placing a surgical port on the body based on the location of the surgical site within the body and the image data, and cause the display device to display the generated graphical guidance.Type: GrantFiled: January 9, 2019Date of Patent: November 7, 2023Assignee: Covidien LPInventors: Dwight Meglan, Meir Rosenberg
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Patent number: 11806088Abstract: A method includes providing medical images of a subject for selecting a target image from thereamong, building a 3D image model based on the medical images and the target image with a surgical target site assigned, performing image registration to superimpose the 3D image model on a real-time image of the subject so as to result in a combined image, determining a virtual entry site located on the combined image, connecting the surgical target site and the virtual entry site with a straight line, generating a guiding path extending from the virtual entry site, in a direction away from the surgical target site and along the straight line, and displaying the guiding path for guiding a surgical instrument.Type: GrantFiled: March 30, 2021Date of Patent: November 7, 2023Assignees: CHANG GUNG UNIVERSITY, CHANG GUNG MEMORIAL HOSPITAL, KEELUNGInventors: Shin-Yan Chiou, Pin-Yuan Chen, Hao-Li Liu, Kuo-Chen Wei
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Patent number: 11800979Abstract: An aspect of some embodiments of the present invention relates to a method for determining one or more characteristics of a region of interest. The method includes providing stimulation for exciting the region of interest for a first selected time period; monitoring mechanical response of the region of interest for at least a second time period after said first time period; processing data indicative of said mechanical response, and determining data on one or more measures of motion of the region of interest; utilizing data on one or more measures of motion for yielding at least one damping parameter indicative of damping of the mechanical response of the region of interest, and determining at least one characteristic of the region of interest in accordance with at least one damping parameter.Type: GrantFiled: December 2, 2018Date of Patent: October 31, 2023Assignee: BAR ILAN UNIVERSITYInventors: Zeev Zalevsky, Aviya Bennett, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman
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Patent number: 11793399Abstract: Super resolution and color motion artifact correction in a pulsed hyperspectral imaging system. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation with a pixel array of an image sensor to generate a plurality of exposure frames. The method includes detecting motion across two or more sequential exposure frames, compensating for the detected motion, and combining the two or more sequential exposure frames to generate an image frame. The method is such that at least a portion of the plurality of pulses of electromagnetic radiation emitted by the emitter comprises one or more of electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, or from about 900 nm to about 1000 nm.Type: GrantFiled: December 18, 2019Date of Patent: October 24, 2023Assignee: Cilag GmbH InternationalInventors: Joshua D. Talbert, Donald M. Wichern
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Patent number: 11786158Abstract: A bladder fullness monitoring systems includes a controller and an active optical sensor that is affixed to a patient's bladder. The sensor emits light onto the bladder and further detects light reflected from the bladder, in order to generate an output signal that indicates an amount of emitted light was reflected back to the detector. The controller is coupled to the optical sensor to receive and interpret the output signals, e.g., to determine when the bladder is full. The controller may be operatively coupled to a urinary control apparatus which uses the output signals to trigger urination in patients who have lost the ability to voluntarily urinate. Embodiments are particularly useful for monitoring bladder fullness in patients who have lost bladder sensation and/or the ability to voluntary urinate and rely on a urinary control apparatus in order to urinate.Type: GrantFiled: December 21, 2018Date of Patent: October 17, 2023Assignee: InCube Labs, LLCInventors: Ralph Walter Peterson, Kyle Horlen, Stephen R. Kraus, Paul Spehr, Elmar Fischer, Varghese George, Mir A. Imran
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Patent number: 11782258Abstract: An endoscopic inspection system comprises: a switchable light source device for alternately providing first illumination light and second illumination light to illuminate an inspection location; an endoscope device for acquiring first image data of the inspection location under the illumination of the first illumination light, and acquiring second image data of the inspection location under the illumination of the second illumination light; a processor communicatively connected to the switchable light source device and the endoscope device, wherein the processor determines, according to the first image data and/or the second image data, whether the first image data and/or the second image data contains an abnormal region, and further generates determination data associated with the first image data and/or the second image data; and a display device communicatively connected to the processor for displaying the first image data and the second image data respectively according to a first display instruction andType: GrantFiled: January 21, 2020Date of Patent: October 10, 2023Assignee: aetherAI Co., Ltd.Inventor: Cheng-Che Chen
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Patent number: 11779219Abstract: A system for providing intraoperative feedback to a user during the course of surgery. A core imaging unit provides low-coherence optical radiation coupled to a sampling device and generates optical coherence tomography (OCT) data based on combining scattered light received from the sampling device together with a reference signal. The sampling device is adapted to receive the low-coherence optical radiation from the core imaging unit and to illuminate the tissue, and to collect light scattered by the tissue and to return said light to the core imaging unit. A core software unit receives the OCT data from the core imaging unit provides real-time feedback, such as an image, to the user via an indicator.Type: GrantFiled: December 20, 2018Date of Patent: October 10, 2023Assignee: The Board of Trustees of the University of IllinoisInventors: Stephen A. Boppart, Freddy T. Nguyen, Adam M. Zysk
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Patent number: 11771324Abstract: Embodiments related to methods of use of an image analysis system for identifying residual cancer cells after surgery are disclosed. In some embodiments, the image analysis system collects a surgical site image and indicates on a display one or more locations of the identified cancer cells. In some embodiments, the method for identifying residual cancer cells comprises determining and selecting a portion of the surgical site image responsive to an intensity parameter; modifying the selected portion of the surgical site image to determine one or more groups of residual cancer cells based on size; and identifying at least one of the one or more groups of residual cancer cells from the modified portion of the surgical site image using a local-based threshold.Type: GrantFiled: July 5, 2022Date of Patent: October 3, 2023Assignee: Lumicell, Inc.Inventors: David B. Strasfeld, W. David Lee, Jorge Ferrer
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Patent number: 11771362Abstract: An optical measurement system includes a wearable module having at least one time-resolved single photon photodetector configured to detect photons from at least one light pulse after the at least one light pulse is scattered by a target within a body of a user; at least one light guide configured to receive the photons and guide the photons to the at least one photodetector; and a housing that houses both the at least one photodetector and at least a portion of the at least one light guide. The optical measurement system further includes a signal processing circuit configured to determine a temporal distribution of the photons detected by the at least one photodetector and generate a histogram based on the temporal distribution of the photons.Type: GrantFiled: February 16, 2021Date of Patent: October 3, 2023Assignee: HI LLCInventors: Scott Jeremy Seidman, Ryan Field, Isai Olvera, Jennifer Rines
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Patent number: 11771333Abstract: An electronic device is provided which can be worn on the body or implanted into the body, such as in the form of a pulse watch and/or a smartwatch and/or an implant. The electronic device includes a photoplethysmographic measuring device. A transmitter diode and a receiver diode are arranged under a window made of glass or glass ceramics. The window is implemented as a compression glass seal and/or as a fiber-optic plate.Type: GrantFiled: May 6, 2021Date of Patent: October 3, 2023Assignee: Schott AGInventors: Robert Hettler, Wee Kiat Chai, Rainer Graf, Helena BlĂ¼mel
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Patent number: 11771880Abstract: An apparatus for an implantable venous access port with remote physiological monitoring capabilities is disclosed. A system and method also perform the functions of the apparatus. In one embodiment the apparatus includes a chemotherapy access port, a plurality of sensors integrated with the chemotherapy access port, where the plurality of sensors determine one or more chemotherapy-related physiological indicators and the one or more physiological indicators include at least parameters selected from red blood cell count, white blood cell count, platelets, and/or ejection fraction. The apparatus includes a communications module integrated with the chemotherapy access port, where the communications module is configured to communicate the one or more chemotherapy-related physiological indicators to a computing device.Type: GrantFiled: July 17, 2020Date of Patent: October 3, 2023Assignee: NXGENPORT, LLCInventors: Cathy Skinner, Rosanne Welcher, Mohamed Ali, Aenor Sawyer
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Patent number: 11762179Abstract: In a method for operating a microscope, a lens unit transmits a first image laser to an object, and acquire a first scan image on the basis of a first reflection signal reflected from a first area included in the object. An ultrasound conversion unit transmits an ultrasound signal to the first area and focuses same so as to form air bubbles in the first area. The lens unit transmits a second image laser to the object, and can acquire a second scan image on the basis of a second reflection signal reflected from the second area included in the object. The ultrasound conversion unit transmits an ultrasound signal to the first area included in the object and focuses same so as to form air bubbles in the first area, thereby enabling an increase in the imageable depth of a microscope.Type: GrantFiled: February 25, 2020Date of Patent: September 19, 2023Assignees: SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION, DAEGU GYEONGBOK INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Jin Ho Chang, Sung Hun Park
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Patent number: 11754021Abstract: Aircraft propulsion systems including a closed loop-supercritical fluid system having a turbine, a cooler heat exchanger, a compressor, and a recovery heat exchanger arranged along a closed-loop flow path of a supercritical fluid. A shaft is operably coupled to the turbine and configured to be rotationally driven by the turbine. A fan is configured to generate thrust, the fan operably coupled to the shaft to be rotationally driven by the shaft. A burner is configured to combust a fuel and air from the fan to generate a combusted gas and supply said combusted gas to the recovery heat exchanger of the closed loop-supercritical fluid system and out an exhaust nozzle.Type: GrantFiled: August 20, 2021Date of Patent: September 12, 2023Assignee: RAYTHEON TECHNOLOGIES CORPORATIONInventors: Amanda Jean Learned Boucher, Joseph B. Staubach
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Patent number: 11751769Abstract: Systems and methods directed to the assessment of circulatory complications due to advancement of diabetes. Embodiments include an optical measurement device having a light source with one or more wavelengths and configured to illuminate an area of tissue, a detector configured to capture the light reflecting from one or more layers of the tissue at the one or more illumination wavelengths, a processor configured to compute, based on the detected signal of layer extracted circulatory data, one or more estimates of tissue vascular health, and a display or communication device (e.g., electronic data transfer) configured to store or report the tissue vascular health. In exemplary embodiments, the distribution of chromophores such as hemoglobin in different layers of skin is extracted using a combination of structured light in the visible and near-infrared regime.Type: GrantFiled: September 9, 2019Date of Patent: September 12, 2023Assignee: MODULATED IMAGING, INC.Inventors: David Cuccia, Amaan Mazhar
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Patent number: 11744439Abstract: In various embodiments, a scope-based imaging system is introduced. An optical sensor assembly located at the tip of the scope may include the CMOS sensors, filters, and lenses/mirrors, to perform fluorescence imaging using the scope.Type: GrantFiled: June 15, 2022Date of Patent: September 5, 2023Assignee: Curadel, LLCInventor: John V. Frangioni
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Patent number: 11719920Abstract: Provided are an imaging unit 104 that uses a light emitted from a second beam splitter 202 of a microscope 2 that can use an exciting light and an observation light, which is a light including a wavelength other than that of the exciting light, as a light source by switching there between and is provided with the second beam splitter 202 to image images of the same observation region of the microscope 2 in situations where the exciting light and the observation light are used as the light source and an output unit 106 that overlaps, synthesizes, and outputs the images imaged by the imaging unit 104 respectively using the exciting light and the observation light as the light source.Type: GrantFiled: November 5, 2020Date of Patent: August 8, 2023Assignee: Leica Microsystems (Schweiz) AGInventors: Kyosuke Kamada, Yukie Tamura, Fumiya Takeuchi
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Patent number: 11712196Abstract: The invention provides a system (1) comprising a sensor (100) for measuring a skin parameter, the sensor (100) comprising (i) a plurality of spatially separated light sources (110) configured to provide light source light (111), and (ii) a detector (120) configured at a first distance (d1) from each of the light sources (110), wherein the first distance (d1) is selected from the range of 5-80 mm, wherein the sensor (100) is configured to provide the light source light (111) with optical axes (OL) under an angle (?) relative to an optical axis (O2) of the detector (120) selected from the range of 10-80°, wherein the sensor (100) comprises at least three light sources (110), wherein the light sources (110) are configured to provide unpolarized light source light (111), wherein the sensor (100) further comprises (iii) a sensor opening (107) downstream of the light sources (110) and upstream of the detector (120) for propagation of the light source light (111) out of the sensor (100) and for entrance of reflectedType: GrantFiled: November 1, 2018Date of Patent: August 1, 2023Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Arnoldus Johannes Martinus Jozeph Ras, Walter Hermans, Pascal Jean Henri Bloemen, Babu Varghese
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Patent number: 11696695Abstract: A method and an apparatus for measuring a time-varying change in an amount of blood in a tissue include exciting a fluorescence agent in the blood, acquiring a time-varying light intensity signal during a pulsatile flow of the blood through the tissue volume, the pulsatile flow having a systolic and a diastolic phase resembling a conventional photoplethysmogram, and processing the acquired signal by applying a modified Beer-Lambert law to obtain the measurement of the time-varying change in the amount of blood in the tissue volume. The instantaneous molar concentration of the fluorescence agent is determined by utilizing a concentration-mediated change in a fluorescence emission spectrum of the fluorescence agent.Type: GrantFiled: September 30, 2019Date of Patent: July 11, 2023Assignee: Stryker European Operations LimitedInventors: Robert W. Flower, Robert Anthony Stead, Arthur E. Bailey
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Patent number: 11690562Abstract: A system includes a sensor for measuring a skin parameter. The sensor includes at least three spatially separated light sources for providing unpolarized visible light, a detector located at a first distance from each of the light sources selected from the range of 10-80 mm and at a second distance from the skin, and a polarizer including one or more of a segmented polarizer and a spatially varying polarizer. In a sensing mode, the light sources are configured to sequentially illuminate the skin with the light with optical axes at an angle of incidence selected from the range of 10°-80°, and the detector is configured to sequentially detect light reflected from the skin and generate corresponding detector signals.Type: GrantFiled: April 2, 2018Date of Patent: July 4, 2023Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Babu Varghese, Arnoldus Johannes Martinus Jozeph Ras, Rieko Verhagen
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Patent number: 11684273Abstract: In various embodiments, the present disclosure provides devices and systems for detecting the blood pressure of a user. In one embodiment, an optoelectronic device includes an array of avalanche photodiodes operating in Geiger mode. A tunable optical filter is optically coupled to the array and receives a light beam reflected from a vascularized tissue of the user, in response to the vascularized tissue being illuminated by an optical source.Type: GrantFiled: May 10, 2018Date of Patent: June 27, 2023Assignee: STMICROELECTRONICS S.R.L.Inventors: Massimo Cataldo Mazzillo, Piero Fallica, Sebania Libertino
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Patent number: 11686721Abstract: A cell image analysis apparatus that can achieve less time and effort for labeling for generation of teaching data than in a conventional example is provided. The cell image analysis apparatus includes an image obtaining unit that obtains a cell image including a removal target that is obtained by a microscope for observation of a cell, a teaching data generator that specifies a removal target region including the removal target within the cell image by performing predetermined image processing and generates as teaching data for machine learning, a label image that represents a location of the removal target region in the cell image, and a training data set generator that generates a set of the cell image and the label image as a training data set to be used in machine learning.Type: GrantFiled: March 20, 2018Date of Patent: June 27, 2023Assignee: Shimadzu CorporationInventor: Wataru Takahashi
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Patent number: 11686618Abstract: Disclosed are hyperspectral/multiple spectral imaging methods and devices. A method obtains first and second spectral image datasets of a region of interest (ROI). The first spectral image dataset is characterized by a first spectral range and the second spectral image dataset is characterized by a second spectral range. The method then performs a first spectral analysis on the first spectral image dataset and a second spectral analysis on the second spectral image dataset. Afterwards, the method determines one or more spectral signature(s) at a deeper layer of the ROI.Type: GrantFiled: January 25, 2021Date of Patent: June 27, 2023Assignee: Hypermed Imaging, Inc.Inventors: Mark Anthony Darty, Peter Martin Meenen
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Patent number: 11684330Abstract: Methods and systems for X-ray and fluoroscopic image capture and, in particular, to a versatile, multimode imaging system incorporating a handheld X-ray emitter operative to capture non-invasive images of a target; a stage operative to capture static X-ray and dynamic fluoroscopic images of the target; a system for the tracking and positioning of the X-ray emission to improve safety of obtaining X-ray images as well as improve the quality of X-ray images. Where the devices can automatically limit the field of the X-ray emission.Type: GrantFiled: April 12, 2022Date of Patent: June 27, 2023Assignee: OXOS Medical, Inc.Inventors: Evan Ruff, Gregory Kolovich, Dev Mandavia, Dhruv Vishwakarma, Igor Zamlinsky, Sean Dolan
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Patent number: 11678941Abstract: Medical software tools platform utilizes a surgical display to provide access to specific medical software tools, such as medically-oriented applications or widgets, that can assist those in the operating room, such as a surgeon or surgical team, with a surgery. In particular, an optical sensor located within an endoscopic camera may register the momentary change in the optical characteristics reflected from a tissue surface and in turn transmit the information to a medical image processing system which can also receive patient heart rate data and display relevant anomalies. Changes in various spectral components and the speed at which they change in relation to a source of stimulus (heartbeat, etc.) may indicate the arrival of blood, contrast agents or oxygen absorption. Combinations of these may indicate various states of differing disease or margins of tumors, and so forth. Also, changes in temperatures and the speed of change may indicate subsurface anomalies.Type: GrantFiled: January 12, 2022Date of Patent: June 20, 2023Inventor: Jack Wade
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Patent number: 11678713Abstract: Presented are intelligent electronic footwear and apparel with controller-automated features, methods for making/operating such footwear and apparel, and control systems for executing automated features of such footwear and apparel. A method for operating an intelligent electronic shoe (IES) includes receiving, e.g., via a controller through a wireless communications device from a GPS satellite service, location data of a user. The controller also receives, e.g., from a backend server-class computer or other remote computing node, location data for a target object or site, such as a virtual shoe hidden at a virtual spot. The controller retrieves or predicts path plan data including a derived route for traversing from the user's location to the target's location within a geographic area. The controller then transmits command signals to a navigation alert system mounted to the IES's shoe structure to output visual, audio, and/or tactile cues that guide the user along the derived route.Type: GrantFiled: August 17, 2021Date of Patent: June 20, 2023Assignee: NIKE, Inc.Inventors: Christopher Andon, Hien Tommy Pham
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Patent number: 11675112Abstract: An electronic device includes a substrate, a plurality of light sources, the plurality of light sources configured to emit an optical signal to an object through the substrate, at least one sensor underneath the substrate, the at least one sensor configured to detect biometric information associated with the object by receiving a reflected light signal, the reflected light signal corresponding to the optical signal reflected off the object and transferred through the substrate, and a multi-lens array including at least one support layer, a plurality of first lenses, and a plurality of second lenses, the at least one support layer in an upper portion of the at least one sensor, the plurality of first lenses on an upper surface of the at least one support layer, and the plurality of second lenses on a lower surface of the at least one support layer.Type: GrantFiled: March 2, 2020Date of Patent: June 13, 2023Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Kyunghwan Lee, Daekwan Kim, Yohwan Noh
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Patent number: 11670143Abstract: A method and system for communicating estimated blood loss parameters of a patient to a user, the method comprising: receiving data representative of an image, of a fluid receiver; automatically detecting a region within the image associated with a volume of fluid received at the fluid receiver, the volume of fluid including a blood component; calculating an estimated amount of the blood component present in the volume of fluid based upon a color parameter represented in the region, and determining a bias error associated with the estimated amount of the blood component; updating an analysis of an aggregate amount of the blood component and an aggregate bias error associated with blood loss of the patient, based upon the estimated amount of the blood component and the bias error; and providing information from the analysis of the aggregate amount of the blood component and the aggregate bias error, to the user.Type: GrantFiled: February 15, 2021Date of Patent: June 6, 2023Assignee: Gauss Surgical, Inc.Inventors: Siddarth Satish, Andrew T. Hosford, Kevin J. Miller, Milton McColl, Juan Carlos Aragon
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Patent number: 11642070Abstract: A device and system for non-invasively measuring wavelength-dependent changes in optical absorption of brain tissue damaged by CTE, TBI, concussion, repetitive trauma, and/or Lou Gehrig's disease in comparison to signals from healthy normal tissue for a subject in vivo. The brain, tissues, and fluids superficial to the brain are trans-cranially illuminated by light source(s) in low-absorption spectral windows for tissue in the visible and/or near-infrared parts of the spectrum. Optode(s) are disposed at predetermined radial distance(s) from a light output to collect the scattered and/or deflected signal from the surface of the head. The predetermined radial distance from the light output to the optode is correlated with the depth of tissue penetration for the light collected by the optode. A spectrometer and computer analyze the collected light for characteristic optical signatures of the brain tissue damage utilizing the absorbance and/or reflectance and/or transmission spectra generated as a result.Type: GrantFiled: July 18, 2018Date of Patent: May 9, 2023Assignee: Headwall Photonics, Inc.Inventors: David Bannon, Domhnull Granquist-Fraser, Paul Bartel, Kevin Didona, Carson Roberts, Blair Simon
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Patent number: 11645745Abstract: Embodiments described herein may provide devices, systems, methods, and/or computer readable medium for adverse event detection and severity estimation in surgical videos. The system can train multiple models for adverse detection and severity estimation. The system can load selected models for real-time adverse event detection and severity estimation.Type: GrantFiled: February 14, 2020Date of Patent: May 9, 2023Assignee: SURGICAL SAFETY TECHNOLOGIES INC.Inventors: Haiqi Wei, Teodor Pantchev Grantcharov, Babak Taati, Yichen Zhang, Frank Rudzicz, Kevin Lee Yang
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Patent number: 11636664Abstract: The present disclosure provides a training method and device of a neural network for medical image processing, a medical image processing method and device, and an electronic apparatus for medical image processing based on a neural network. The training method includes performing a pre-processing process on an original image to obtain a pre-processed image, performing a data-augmenting process on the pre-processed image to obtain an augmented image retaining a pathological feature, the augmented image including at least one image with first resolution and at least one image with second resolution being higher than the first resolution, and training the neural network by selecting the image with first resolution and a part-cropping image from the image with second resolution as training samples.Type: GrantFiled: August 2, 2018Date of Patent: April 25, 2023Assignee: BOE TECHNOLOGY GROUP CO., LTD.Inventors: Yingying Li, Lvwei Wang