Visible Light Radiation Patents (Class 600/476)
  • Patent number: 12042258
    Abstract: Disclosed is an apparatus for measuring photoplethysmogram. The apparatus includes a ring structure with at least one photon source and at least one photon detector positioned on an inner surface of the ring structure. The apparatus further includes a controller configured to measure a preliminary photoplethysmogram during a first time period by taking a first number of samples, determine a form factor from said preliminary photoplethysmogram, determine an inter beat interval from said preliminary photoplethysmogram, and use the form factor and the inter beat interval to determine a second number of samples to be taken during a second time period of measurement of the photoplethysmogram and the distribution of the samples to be taken in function of time.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: July 23, 2024
    Assignee: Oura Health Oy
    Inventors: Harri Matti-Heikki Laakkonen, Hannu Olavi Kinnunen, Markku Olavi Koskela
  • Patent number: 12038572
    Abstract: The present specification describes a novel system for dynamically modifying the magnification power of optical devices used in high performance and critical applications such as medical procedures. The present specification describes an optical imaging system having a magnification control system connected to a sensor device for enabling movement of sensor device with respect to a lens assembly of the imaging system, wherein distance between the sensor device and the lens assembly is altered to enable different levels of magnification capability.
    Type: Grant
    Filed: November 8, 2021
    Date of Patent: July 16, 2024
    Assignee: EndoChoice, Inc.
    Inventors: Amram Aizenfeld, Leonid Krivopisk
  • Patent number: 12029578
    Abstract: A skin diagnosing device includes an optical unit including: an optical system that uses OCT; an optical mechanism to guide light from the optical unit to skin to scan the skin; a loading device to apply predetermined deformation energy to the skin; a control computation unit to compute tomographic distribution of predetermined status values relating to the skin by controlling driving of the loading device and the optical mechanism and processing optical interference signals output from the optical unit in response to the driving, to compute an evaluation value of the skin based on the tomographic distribution; and a display device to display the evaluation value of the skin. The control computation unit computes the evaluation value by computing mechanical characteristics and a blood flow condition of the skin as the status values and associating the mechanical characteristics and the blood flow condition at a cross-sectional position of the skin.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: July 9, 2024
    Assignees: SHISEIDO COMPANY, LTD., MEIJO UNIVERISTY
    Inventors: Souichi Saeki, Yusuke Hara, Toyonobu Yamashita
  • Patent number: 12029584
    Abstract: Embodiments describe a light-based medical device that uses light to luminesce tissue, and collect the reflected light, to perform analysis on the reflection characteristics in real-time to detect the type of surrounding tissue as well deeper tissue in the trajectory of the luminescence. Such device can be incorporated inside needles, catheters, tubes or piercing or biopsy tools, surgical blades, surgical tweezers, and so on, to direct their insertions and operations in specific zones. Importantly, because of the easy-to-use design, embodiments can be used without the need of highly trained personnel or expensive hospital equipment. Therefore, embodiments can be utilized in emergency situations that require fast responses, performed in ERs, moving vehicles, ambulances, and battlefields.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: July 9, 2024
    Inventor: Avid Najdahmadi
  • Patent number: 12025556
    Abstract: An optical property measurement method includes: measuring, by first measurement, optical intensity of backscattering from a measurement target object when light is beamed to the measurement target object; calculating an attenuation coefficient in a depth direction of the measurement target object based on a measurement result of the first measurement; measuring, by second measurement that is different from the first measurement, optical intensity of backscattering from the measurement target object when light is beamed to the measurement target object; and calculating a scattering coefficient and an absorption coefficient in the depth direction of the measurement target object based on a measurement result of the second measurement by using a value of the calculated attenuation coefficient as a limiting condition.
    Type: Grant
    Filed: December 2, 2021
    Date of Patent: July 2, 2024
    Assignee: OLYMPUS CORPORATION
    Inventor: Tomoko Sato
  • Patent number: 12016674
    Abstract: The present invention relates to the field of medical monitoring, and in particular non-contact, video-based monitoring of pulse rate, respiration rate, motion, and oxygen saturation. Systems and methods are described for capturing images of a patient, producing intensity signals from the images, filtering those signals to focus on a physiologic component, and measuring a vital sign from the filtered signals. Examples include flood fill methods and skin tone filtering methods.
    Type: Grant
    Filed: May 9, 2022
    Date of Patent: June 25, 2024
    Assignee: Covidien LP
    Inventors: Dominique Jacquel, Paul Stanley Addison, David Foo
  • Patent number: 12011227
    Abstract: Methods and systems for intraoperatively determining alignment parameters of a spine during a spinal surgical procedure are disclosed herein. In some embodiments, a method of intraoperatively determining an alignment parameter of a spine during a surgical procedure includes receiving initial image data of the spine including multiple vertebrae and identifying a geometric feature associated with each vertebra in the initial image data. The geometric features each have a pose in the initial image data and characterize a three-dimensional (3D) shape of the associated vertebra. The method further comprises receiving intraoperative image data of the spine and registering the initial image data to the intraoperative image data. The method can then update the pose of each geometric feature based on the registration and the intraoperative image data, and determine the alignment parameter based on the updated poses of the geometric features associated with two or more of the vertebrae.
    Type: Grant
    Filed: May 3, 2022
    Date of Patent: June 18, 2024
    Assignee: PROPRIO, INC.
    Inventors: Robert Bruce Grupp, Jr., David Lee Fiorella, Thomas A. Carls, Samuel R. Browd, Adam Gabriel Jones, James Andrew Youngquist, Richard Earl Simpkinson
  • Patent number: 11994461
    Abstract: An optical probe includes an optical window for transmitting light therethrough, an ultrasonic transducer for applying ultrasonic vibrations to the optical window for cleaning the optical window, and one or more light guides for transmitting light through the optical window to a measurement region and/or receiving light transmitted through the optical window from the measurement region. The ultrasonic transducer is coupled to the optical window via an elongate body adapted to transmit ultrasonic vibrations from the ultrasonic transducer to the window. The light guides communicate with the optical window adjacent the elongate body. An additional lens or light filter may be mounted adjacent the measurement window and/or the window itself may be adapted to incorporate a lens and/or light filter.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: May 28, 2024
    Assignee: Inov8 Systems Limited
    Inventors: Khalid Thabeth, Raymond Acheson
  • Patent number: 11992302
    Abstract: A system for non-invasively determining an indication and/or an assessment of intracranial pressure (ICP) is featured. The system includes at least one intracranial light source adapted to be placed on skin above a cranium of a living subject configured to emit light which penetrates the cranium and targets intracranial space of a living subject. The system includes a least one extracranial light source adapted to be placed on skin above a predetermined area of the living subject configured to emit light which penetrates and targets extracranial space of the living subject. A detector subsystem including at least a first detector is configured to detect reflected light from the intracranial space and the extracranial space and is configured to output intracranial output signals associated with light detected from the intracranial space and/or output extracranial output signals associated with light detected from the extracranial space.
    Type: Grant
    Filed: August 6, 2021
    Date of Patent: May 28, 2024
    Assignee: Vivonics, Inc.
    Inventor: Michele Pierro
  • Patent number: 11954766
    Abstract: A method for correcting a shading in a digital image of a three-dimensional observation object obtained by at least one image sensor of an optical observation device is provided. The three-dimensional observation object is illuminated by illumination light and an intensity distribution, and an inhomogeneity in an image brightness is present in the digital image of the three-dimensional observation object. The method includes ascertaining a topography of the three-dimensional observation object, correcting the inhomogeneity in the image brightness of the digital image based on the topography of the three-dimensional observation object and the intensity distribution of the illumination light. In addition, an optical observation system is provided to perform the method.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: April 9, 2024
    Assignee: Carl Zeiss Meditec AG
    Inventors: Dominik Scherer, Susanne Kohlhammer, Stefan Saur
  • Patent number: 11944390
    Abstract: Systems and methods are provided in which an intraoperative video feed is augmented with one or more virtual display features based on a detected orientation and position of the tracked medical instrument. In some example embodiments, the virtual display features may be employed to represent, in an augmented video feed, information associated with a previously-detected intraoperative position and orientation of the tracked medical instrument. The virtual display element may be employed, for example, to facilitate the alignment of an untracked medical instrument with a previously determined intraoperative position and orientation of the tracked medical instrument. In other example embodiments, the virtual display element may be dynamically displayed in a fixed spatial relationship relative to the tracked medical instrument.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: April 2, 2024
    Assignee: 7D Surgical ULC
    Inventors: Adrian Mariampillai, Victor X. D. Yang, Kenneth Kuei-Ching Lee, Michael K. K. Leung, Beau Anthony Standish
  • Patent number: 11937899
    Abstract: An imaging system includes an illuminator for providing illumination on a region of interest, one or more first detectors for detecting reflections of the illumination, and a processing unit. The processing unit is configured to: receive a first image containing the region of interest; determine a first region of high specular reflection in the first image based on the reflections of the illumination on the region of interest; mask the first image by substituting a default color designating masking to alert a user to incomplete image information in the first region of high specular reflection to create a masked first image; and generate a composite image based on the masked first image and a fluorescence image of the region of interest.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: March 26, 2024
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Mahdi Azizian, Jonathan M. Sorger
  • Patent number: 11937906
    Abstract: Systems and methods for monitoring blood flow metrics using a patch of a flexible substrate configured to attach to an area of skin over a blood vessel. The patch includes a plurality of light sources arranged on the substrate to form a matrix and a row of photodetectors disposed on the substrate substantially in parallel with the rows of LEDs. The patch includes an optical signal interface configured to drive each light source and to input an intensity signal at one of the photodetectors. The intensity signals are used to determine AC and DC components corresponding to each optical path. AC to DC component ratios are calculated for each optical path and used to determine ratio-of-ratio values. At least a subset of the ratio-of-ratio values are used to determine a biological metric or a cross-sectional area of the blood vessel.
    Type: Grant
    Filed: April 11, 2021
    Date of Patent: March 26, 2024
    Assignee: Alio, Inc.
    Inventors: Andrei Afanasiev, Forrest Miller, Francis Honore, Anthony Flannery
  • Patent number: 11933727
    Abstract: A computer-implemented system for determining an analyte in milk is provided. The system first causes irradiation of the sample with light in a plurality of discrete spectral bands. The spectral bands can be selected based on phenomenon of specific analytes. The irradiation causes a fluorescent response in the milk, which is received by light sensors and converted into digitized spectral data. The digitized spectral data is then transmitted to a machine learning system which can determine the concentration of analytes and produce an output indicative of said concentration.
    Type: Grant
    Filed: February 6, 2023
    Date of Patent: March 19, 2024
    Assignee: Labby Inc.
    Inventors: Anshuman Das, Julia Kang Somerdin
  • Patent number: 11925413
    Abstract: A computer-implemented method, a computer program, a system and a method for analyzing a time-velocity curve and calculating based on the time-velocity curve ophthalmic parameters.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: March 12, 2024
    Inventor: Arash Ghareh Baghi
  • Patent number: 11925459
    Abstract: A medical system recommends a posture of a subject during a medical procedure. The medical system includes a processor and an output device. The processor determines suitable postures of the subject during the medical procedure based on at least one of subject information, including information on a posture of the subject obtained upon a predetermined movement by the subject and information on the procedure. The output device presents one or more of the suitable postures determined by the processor as recommended postures.
    Type: Grant
    Filed: September 10, 2020
    Date of Patent: March 12, 2024
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Yusuke Sekine, Yuki Sakaguchi, Akihiko Tarunaga
  • Patent number: 11918351
    Abstract: A method of non-invasively monitoring hemoglobin concentration includes providing incident light to patient tissue at a first excitation wavelength. The method further includes monitoring a first emission response at a first emission wavelength, wherein the first emission wavelength is selected to correspond with a maximum of the emission response, and monitoring a second emission response at a second emission wavelength, wherein the second emission wavelength is selected to correspond with a minimum of the emission response. A hemoglobin concentration is calculated based on a ratio of the first emission response to the second emission response.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: March 5, 2024
    Assignee: Medtronic Monitoring, Inc.
    Inventor: Rodolphe Katra
  • Patent number: 11915413
    Abstract: An endoscope system includes a light source apparatus, an illumination-light setting section capable of setting, as illumination light for illuminating an object including a biological tissue, first illumination light obtained by combining light in one or more wavelength bands selected from the light in plural wavelength bands and second illumination light obtained by combining light in one or more wavelength bands different from the first illumination light, selected out of the light in the plural wavelength bands, a light-source control section, and an image analyzing section configured to acquire an analysis result related to presence or absence of an abnormal finding. The illumination-light setting section sets, based on the analysis result of the image analyzing section for the first image acquired by the first illumination light, a combination of light in wavelength bands included in the second illumination light to be irradiated next.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: February 27, 2024
    Assignee: OLYMPUS CORPORATION
    Inventor: Kenji Yamazaki
  • Patent number: 11900556
    Abstract: A computer system obtains at least one 3D scan of a body surface; automatically identifies, based on the at least one 3D scan, one or more features (e.g., nose, lips, eyes, eyebrows, cheekbones, or specific portions thereof, or other features) of the body surface; and generates a digital 3D model of the body surface. The digital 3D model includes the identified features of the human body surface. In an embodiment, the step of generating of the digital 3D model is based on the at least one 3D scan and the identified features of the body surface. In an embodiment, the digital 3D model comprises a 3D mesh file. The digital 3D model can be used in various ways. For example, output of a manufacturing process (e.g., a 3D printed item, a cosmetics product, a personal care product) can be based on the digital 3D model.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: February 13, 2024
    Assignee: L'Oreal
    Inventors: David B. Kosecoff, Aldina Suwanto, Grégoire Charraud
  • Patent number: 11883130
    Abstract: A detecting device includes a semiconductor substrate, a first light-emitting section provided in a layered manner at the semiconductor substrate and configured to emit first light having a first wavelength band toward a living body, a second light-emitting section provided at the semiconductor substrate in a layered manner and configured to emit second light having a second wavelength band toward the living body, a first light-receiving section provided at the semiconductor substrate and configured to receive light from the living body based on the first light, a second light-receiving section provided at the semiconductor substrate and configured to receive light from the living body based on the second light, and an optical filter provided at the first light-receiving section and configured to transmit light having the first wavelength band and to attenuate light having the second wavelength band. The second wavelength band is longer than the first wavelength band.
    Type: Grant
    Filed: February 23, 2023
    Date of Patent: January 30, 2024
    Assignee: SEIKO EPSON CORPORATION
    Inventors: Tetsuya Yamamoto, Takefumi Fukagawa
  • Patent number: 11883132
    Abstract: A system for the optical measurement of pH includes a light emitter to emit an excitation light, and a detector coupled to receive florescence light produced by a compound in a mouth of a patient in response to the excitation light. A controller is coupled to the detector, and the controller includes logic that when executed by the controller, causes the system to perform operations. The operations may include emitting the excitation light from the light emitter; measuring an intensity of the florescence light emitted from a surface of individual teeth in a plurality of teeth in the mouth; and determining, based on the intensity of the florescence light, one or more locations on the individual teeth likely to develop demineralization.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: January 30, 2024
    Assignee: University of Washington
    Inventors: Eric J. Seibel, Yuanzheng Gong, Zheng Xu, Jeffrey S. McLean, Yaxuan Zhou
  • Patent number: 11885745
    Abstract: Embodiments disclosed include methods and apparatus for Fluorescent Enhanced Photothermal Infrared (FE-PTIR) spectroscopy and chemical imaging, which enables high sensitivity and high spatial resolution measurements of IR absorption with simultaneous confocal fluorescence imaging. In various embodiments, the FE-PTIR technique utilizes combined/simultaneous OPTIR and fluorescence imaging that provides significant improvements and benefits compared to previous work by simultaneous detection of both IR absorption and confocal fluorescence using the same optical detector at the same time.
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: January 30, 2024
    Assignee: Photothermal Spectroscopy Corp.
    Inventor: Craig Prater
  • Patent number: 11877826
    Abstract: In some aspects, the present disclosure provides methods for identifying a disease in an epithelial tissue of a subject. Methods for identifying a disease in an epithelial tissue comprise the generation of a depth profile of the epithelial tissue using signals generated from the tissue by pulses of light directed towards a surface of the epithelial tissue. In some aspects, the present disclosure provides apparatuses consistent with the methods herein.
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: January 23, 2024
    Assignee: ENSPECTRA HEALTH, INC.
    Inventors: Gabriel Sanchez, Fred Landavazo, IV, Scott Delp, Kathryn Montgomery
  • Patent number: 11882392
    Abstract: A sound output device according to an exemplary embodiment of the present invention includes: a first housing; a second housing; a substrate; a light emitting unit; and a sound output unit, in which the second housing is connected with the first housing, the substrate is disposed inside the first housing or the second housing, the sound output unit is connected with the substrate, the light emitting unit is connected with the substrate, and the second housing selectively transmits light emitted by the light emitting unit based on a wavelength thereof.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: January 23, 2024
    Assignee: IRTRONIX, INC.
    Inventors: Danny Oh, Chien Nguyen
  • Patent number: 11877845
    Abstract: A method, system, apparatus, and/or device to determine a condition of a user using a spectrometer with a collimator on a glass substrate. The method, system, apparatus, and/or device may include: a band comprising a shape, size, and flexibility designed for attaching the band to a body part of a user; a light source embedded in the band that emits light comprising a constituent wavelength that provides an indication of a feature of the body part; an optical sensor positioned in the band to receive the constituent wavelength; and a glass substrate oriented in the band to receive the light, the glass substrate comprising: an optical filter that comprises a passband to isolate the constituent wavelength from other wavelengths of the light; and a carbon nanotube grid structure comprising walls and through-channels, the carbon nanotube grid structure adhered to the glass substrate.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: January 23, 2024
    Assignee: Brigham Young University
    Inventors: Robert Davis, Richard Vanfleet, Nick Morrill, David Miller
  • Patent number: 11854288
    Abstract: To determine the state of a subject person with a simple structure, an image determining device includes: an imaging unit that captures an image from a first direction, the image including the subject person; a first detector that detects size information from the image, the size information being about the subject person in the first direction; a second detector that detects position-related information, the position-related information being different from the information detected by the first detector; and a determining unit that determines the state of the subject person, based on a result of the detection performed by the first detector and a result of the detection performed by the second detector.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: December 26, 2023
    Assignee: NIKON CORPORATION
    Inventors: Tetsuya Yamamoto, Masahiro Nei, Isao Totsuka, Tomoyuki Matsuyama, Masamitsu Yanagihara, Satoshi Hagiwara, Masakazu Sekiguchi
  • Patent number: 11839484
    Abstract: A method for the objective determination of capillary refill behavior on a human body surface in which a spatially and spectrally resolved optical detection is carried out by at least one detector device (1) at a skin surface area (2) having a predefined areal size and outer contour. Subsequently a predefined pressure p constant over the skin surface area (2) is exerted over a predefined time t1; and the pressure effect is ended after expiry of this time t1. The spatially and spectrally resolved optical detection is carried out by the detector device (1) and the respective capillary refill behavior is spatially and temporally determined at a time t2 up to which at least one first threshold value of the measurement values detected simultaneously with spatial resolution has reached the measurement value that had been optically detected before the start of the pressure effect.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: December 12, 2023
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Uwe Vogel, Bernd Richter, Torsten Richter
  • Patent number: 11813482
    Abstract: The present invention relates to advanced Cherenkov-based imaging systems, tools, and methods of feedback control, temporal control sequence image capture, and quantification in high resolution dose images. In particular, the present invention provides a system and method for simple, accurate, quick, robust, real-time, water-equivalent characterization of beams from LINACs and other systems producing external-therapy radiation for purposes including optimization, commissioning, routine quality auditing, R&D, and manufacture. The present invention also provides a system and method for rapid and economic characterization of complex radiation treatment plans prior to patient exposure. Further, the present invention also provides a system and method of economically detecting Cherenkov radiation emitted by tissue and other media in real-world clinical settings (e.g., settings illuminated by visible light).
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: November 14, 2023
    Assignee: DoseOptics LLC
    Inventors: Venkataramanan Krishnaswamy, Brian W. Pogue
  • Patent number: 11806085
    Abstract: Systems for guiding placement of surgical ports on a body include an image capture device configured to capture an image of an operating environment and generate image data based on the captured image, a display device, and a computing device configured to obtain information regarding a location of a surgical site within the body, receive the image data from the image capture device, generate graphical guidance for placing a surgical port on the body based on the location of the surgical site within the body and the image data, and cause the display device to display the generated graphical guidance.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: November 7, 2023
    Assignee: Covidien LP
    Inventors: Dwight Meglan, Meir Rosenberg
  • Patent number: 11806088
    Abstract: A method includes providing medical images of a subject for selecting a target image from thereamong, building a 3D image model based on the medical images and the target image with a surgical target site assigned, performing image registration to superimpose the 3D image model on a real-time image of the subject so as to result in a combined image, determining a virtual entry site located on the combined image, connecting the surgical target site and the virtual entry site with a straight line, generating a guiding path extending from the virtual entry site, in a direction away from the surgical target site and along the straight line, and displaying the guiding path for guiding a surgical instrument.
    Type: Grant
    Filed: March 30, 2021
    Date of Patent: November 7, 2023
    Assignees: CHANG GUNG UNIVERSITY, CHANG GUNG MEMORIAL HOSPITAL, KEELUNG
    Inventors: Shin-Yan Chiou, Pin-Yuan Chen, Hao-Li Liu, Kuo-Chen Wei
  • Patent number: 11806114
    Abstract: A system for measuring capillary refill time includes a wearable device and a control unit. The wearable device includes a force sensor to obtain a force signal and an optical sensor to obtain an optical signal. The system ensures that an applied force is acceptable in both magnitude and duration, and that a duration over which the applied force is released or removed is acceptable. These factors can establish that a capillary refill time determined or calculated therein is accurate. The system can also determine the capillary refill time based on the force and optical signals obtained by the force and optical sensors, respectively.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: November 7, 2023
    Assignees: ProMedix, Inc., Welch Allyn, Inc., Oregon Health & Science University
    Inventors: David Sheridan, Matthew Lee Hansen, Andrew Kibler, Steven D. Baker, Richard Allen Sunderland, Richard H. Weitzel
  • Patent number: 11800979
    Abstract: An aspect of some embodiments of the present invention relates to a method for determining one or more characteristics of a region of interest. The method includes providing stimulation for exciting the region of interest for a first selected time period; monitoring mechanical response of the region of interest for at least a second time period after said first time period; processing data indicative of said mechanical response, and determining data on one or more measures of motion of the region of interest; utilizing data on one or more measures of motion for yielding at least one damping parameter indicative of damping of the mechanical response of the region of interest, and determining at least one characteristic of the region of interest in accordance with at least one damping parameter.
    Type: Grant
    Filed: December 2, 2018
    Date of Patent: October 31, 2023
    Assignee: BAR ILAN UNIVERSITY
    Inventors: Zeev Zalevsky, Aviya Bennett, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman
  • Patent number: 11793399
    Abstract: Super resolution and color motion artifact correction in a pulsed hyperspectral imaging system. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation with a pixel array of an image sensor to generate a plurality of exposure frames. The method includes detecting motion across two or more sequential exposure frames, compensating for the detected motion, and combining the two or more sequential exposure frames to generate an image frame. The method is such that at least a portion of the plurality of pulses of electromagnetic radiation emitted by the emitter comprises one or more of electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, or from about 900 nm to about 1000 nm.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: October 24, 2023
    Assignee: Cilag GmbH International
    Inventors: Joshua D. Talbert, Donald M. Wichern
  • Patent number: 11786158
    Abstract: A bladder fullness monitoring systems includes a controller and an active optical sensor that is affixed to a patient's bladder. The sensor emits light onto the bladder and further detects light reflected from the bladder, in order to generate an output signal that indicates an amount of emitted light was reflected back to the detector. The controller is coupled to the optical sensor to receive and interpret the output signals, e.g., to determine when the bladder is full. The controller may be operatively coupled to a urinary control apparatus which uses the output signals to trigger urination in patients who have lost the ability to voluntarily urinate. Embodiments are particularly useful for monitoring bladder fullness in patients who have lost bladder sensation and/or the ability to voluntary urinate and rely on a urinary control apparatus in order to urinate.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: October 17, 2023
    Assignee: InCube Labs, LLC
    Inventors: Ralph Walter Peterson, Kyle Horlen, Stephen R. Kraus, Paul Spehr, Elmar Fischer, Varghese George, Mir A. Imran
  • Patent number: 11782258
    Abstract: An endoscopic inspection system comprises: a switchable light source device for alternately providing first illumination light and second illumination light to illuminate an inspection location; an endoscope device for acquiring first image data of the inspection location under the illumination of the first illumination light, and acquiring second image data of the inspection location under the illumination of the second illumination light; a processor communicatively connected to the switchable light source device and the endoscope device, wherein the processor determines, according to the first image data and/or the second image data, whether the first image data and/or the second image data contains an abnormal region, and further generates determination data associated with the first image data and/or the second image data; and a display device communicatively connected to the processor for displaying the first image data and the second image data respectively according to a first display instruction and
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: October 10, 2023
    Assignee: aetherAI Co., Ltd.
    Inventor: Cheng-Che Chen
  • Patent number: 11779219
    Abstract: A system for providing intraoperative feedback to a user during the course of surgery. A core imaging unit provides low-coherence optical radiation coupled to a sampling device and generates optical coherence tomography (OCT) data based on combining scattered light received from the sampling device together with a reference signal. The sampling device is adapted to receive the low-coherence optical radiation from the core imaging unit and to illuminate the tissue, and to collect light scattered by the tissue and to return said light to the core imaging unit. A core software unit receives the OCT data from the core imaging unit provides real-time feedback, such as an image, to the user via an indicator.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: October 10, 2023
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Stephen A. Boppart, Freddy T. Nguyen, Adam M. Zysk
  • Patent number: 11771362
    Abstract: An optical measurement system includes a wearable module having at least one time-resolved single photon photodetector configured to detect photons from at least one light pulse after the at least one light pulse is scattered by a target within a body of a user; at least one light guide configured to receive the photons and guide the photons to the at least one photodetector; and a housing that houses both the at least one photodetector and at least a portion of the at least one light guide. The optical measurement system further includes a signal processing circuit configured to determine a temporal distribution of the photons detected by the at least one photodetector and generate a histogram based on the temporal distribution of the photons.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: October 3, 2023
    Assignee: HI LLC
    Inventors: Scott Jeremy Seidman, Ryan Field, Isai Olvera, Jennifer Rines
  • Patent number: 11771333
    Abstract: An electronic device is provided which can be worn on the body or implanted into the body, such as in the form of a pulse watch and/or a smartwatch and/or an implant. The electronic device includes a photoplethysmographic measuring device. A transmitter diode and a receiver diode are arranged under a window made of glass or glass ceramics. The window is implemented as a compression glass seal and/or as a fiber-optic plate.
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: October 3, 2023
    Assignee: Schott AG
    Inventors: Robert Hettler, Wee Kiat Chai, Rainer Graf, Helena Blümel
  • Patent number: 11771880
    Abstract: An apparatus for an implantable venous access port with remote physiological monitoring capabilities is disclosed. A system and method also perform the functions of the apparatus. In one embodiment the apparatus includes a chemotherapy access port, a plurality of sensors integrated with the chemotherapy access port, where the plurality of sensors determine one or more chemotherapy-related physiological indicators and the one or more physiological indicators include at least parameters selected from red blood cell count, white blood cell count, platelets, and/or ejection fraction. The apparatus includes a communications module integrated with the chemotherapy access port, where the communications module is configured to communicate the one or more chemotherapy-related physiological indicators to a computing device.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: October 3, 2023
    Assignee: NXGENPORT, LLC
    Inventors: Cathy Skinner, Rosanne Welcher, Mohamed Ali, Aenor Sawyer
  • Patent number: 11771324
    Abstract: Embodiments related to methods of use of an image analysis system for identifying residual cancer cells after surgery are disclosed. In some embodiments, the image analysis system collects a surgical site image and indicates on a display one or more locations of the identified cancer cells. In some embodiments, the method for identifying residual cancer cells comprises determining and selecting a portion of the surgical site image responsive to an intensity parameter; modifying the selected portion of the surgical site image to determine one or more groups of residual cancer cells based on size; and identifying at least one of the one or more groups of residual cancer cells from the modified portion of the surgical site image using a local-based threshold.
    Type: Grant
    Filed: July 5, 2022
    Date of Patent: October 3, 2023
    Assignee: Lumicell, Inc.
    Inventors: David B. Strasfeld, W. David Lee, Jorge Ferrer
  • Patent number: 11762179
    Abstract: In a method for operating a microscope, a lens unit transmits a first image laser to an object, and acquire a first scan image on the basis of a first reflection signal reflected from a first area included in the object. An ultrasound conversion unit transmits an ultrasound signal to the first area and focuses same so as to form air bubbles in the first area. The lens unit transmits a second image laser to the object, and can acquire a second scan image on the basis of a second reflection signal reflected from the second area included in the object. The ultrasound conversion unit transmits an ultrasound signal to the first area included in the object and focuses same so as to form air bubbles in the first area, thereby enabling an increase in the imageable depth of a microscope.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: September 19, 2023
    Assignees: SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION, DAEGU GYEONGBOK INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jin Ho Chang, Sung Hun Park
  • Patent number: 11754021
    Abstract: Aircraft propulsion systems including a closed loop-supercritical fluid system having a turbine, a cooler heat exchanger, a compressor, and a recovery heat exchanger arranged along a closed-loop flow path of a supercritical fluid. A shaft is operably coupled to the turbine and configured to be rotationally driven by the turbine. A fan is configured to generate thrust, the fan operably coupled to the shaft to be rotationally driven by the shaft. A burner is configured to combust a fuel and air from the fan to generate a combusted gas and supply said combusted gas to the recovery heat exchanger of the closed loop-supercritical fluid system and out an exhaust nozzle.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: September 12, 2023
    Assignee: RAYTHEON TECHNOLOGIES CORPORATION
    Inventors: Amanda Jean Learned Boucher, Joseph B. Staubach
  • Patent number: 11751769
    Abstract: Systems and methods directed to the assessment of circulatory complications due to advancement of diabetes. Embodiments include an optical measurement device having a light source with one or more wavelengths and configured to illuminate an area of tissue, a detector configured to capture the light reflecting from one or more layers of the tissue at the one or more illumination wavelengths, a processor configured to compute, based on the detected signal of layer extracted circulatory data, one or more estimates of tissue vascular health, and a display or communication device (e.g., electronic data transfer) configured to store or report the tissue vascular health. In exemplary embodiments, the distribution of chromophores such as hemoglobin in different layers of skin is extracted using a combination of structured light in the visible and near-infrared regime.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: September 12, 2023
    Assignee: MODULATED IMAGING, INC.
    Inventors: David Cuccia, Amaan Mazhar
  • Patent number: 11744439
    Abstract: In various embodiments, a scope-based imaging system is introduced. An optical sensor assembly located at the tip of the scope may include the CMOS sensors, filters, and lenses/mirrors, to perform fluorescence imaging using the scope.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: September 5, 2023
    Assignee: Curadel, LLC
    Inventor: John V. Frangioni
  • Patent number: 11719920
    Abstract: Provided are an imaging unit 104 that uses a light emitted from a second beam splitter 202 of a microscope 2 that can use an exciting light and an observation light, which is a light including a wavelength other than that of the exciting light, as a light source by switching there between and is provided with the second beam splitter 202 to image images of the same observation region of the microscope 2 in situations where the exciting light and the observation light are used as the light source and an output unit 106 that overlaps, synthesizes, and outputs the images imaged by the imaging unit 104 respectively using the exciting light and the observation light as the light source.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: August 8, 2023
    Assignee: Leica Microsystems (Schweiz) AG
    Inventors: Kyosuke Kamada, Yukie Tamura, Fumiya Takeuchi
  • Patent number: 11712196
    Abstract: The invention provides a system (1) comprising a sensor (100) for measuring a skin parameter, the sensor (100) comprising (i) a plurality of spatially separated light sources (110) configured to provide light source light (111), and (ii) a detector (120) configured at a first distance (d1) from each of the light sources (110), wherein the first distance (d1) is selected from the range of 5-80 mm, wherein the sensor (100) is configured to provide the light source light (111) with optical axes (OL) under an angle (?) relative to an optical axis (O2) of the detector (120) selected from the range of 10-80°, wherein the sensor (100) comprises at least three light sources (110), wherein the light sources (110) are configured to provide unpolarized light source light (111), wherein the sensor (100) further comprises (iii) a sensor opening (107) downstream of the light sources (110) and upstream of the detector (120) for propagation of the light source light (111) out of the sensor (100) and for entrance of reflected
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: August 1, 2023
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Arnoldus Johannes Martinus Jozeph Ras, Walter Hermans, Pascal Jean Henri Bloemen, Babu Varghese
  • Patent number: 11696695
    Abstract: A method and an apparatus for measuring a time-varying change in an amount of blood in a tissue include exciting a fluorescence agent in the blood, acquiring a time-varying light intensity signal during a pulsatile flow of the blood through the tissue volume, the pulsatile flow having a systolic and a diastolic phase resembling a conventional photoplethysmogram, and processing the acquired signal by applying a modified Beer-Lambert law to obtain the measurement of the time-varying change in the amount of blood in the tissue volume. The instantaneous molar concentration of the fluorescence agent is determined by utilizing a concentration-mediated change in a fluorescence emission spectrum of the fluorescence agent.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: July 11, 2023
    Assignee: Stryker European Operations Limited
    Inventors: Robert W. Flower, Robert Anthony Stead, Arthur E. Bailey
  • Patent number: 11690562
    Abstract: A system includes a sensor for measuring a skin parameter. The sensor includes at least three spatially separated light sources for providing unpolarized visible light, a detector located at a first distance from each of the light sources selected from the range of 10-80 mm and at a second distance from the skin, and a polarizer including one or more of a segmented polarizer and a spatially varying polarizer. In a sensing mode, the light sources are configured to sequentially illuminate the skin with the light with optical axes at an angle of incidence selected from the range of 10°-80°, and the detector is configured to sequentially detect light reflected from the skin and generate corresponding detector signals.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: July 4, 2023
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Babu Varghese, Arnoldus Johannes Martinus Jozeph Ras, Rieko Verhagen
  • Patent number: 11686721
    Abstract: A cell image analysis apparatus that can achieve less time and effort for labeling for generation of teaching data than in a conventional example is provided. The cell image analysis apparatus includes an image obtaining unit that obtains a cell image including a removal target that is obtained by a microscope for observation of a cell, a teaching data generator that specifies a removal target region including the removal target within the cell image by performing predetermined image processing and generates as teaching data for machine learning, a label image that represents a location of the removal target region in the cell image, and a training data set generator that generates a set of the cell image and the label image as a training data set to be used in machine learning.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: June 27, 2023
    Assignee: Shimadzu Corporation
    Inventor: Wataru Takahashi
  • Patent number: 11684273
    Abstract: In various embodiments, the present disclosure provides devices and systems for detecting the blood pressure of a user. In one embodiment, an optoelectronic device includes an array of avalanche photodiodes operating in Geiger mode. A tunable optical filter is optically coupled to the array and receives a light beam reflected from a vascularized tissue of the user, in response to the vascularized tissue being illuminated by an optical source.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: June 27, 2023
    Assignee: STMICROELECTRONICS S.R.L.
    Inventors: Massimo Cataldo Mazzillo, Piero Fallica, Sebania Libertino