Visible Light Radiation Patents (Class 600/476)
  • Patent number: 11074448
    Abstract: A method for mapping 2-dimensional point of interest to a 3-dimensional view. The disclosed method includes capturing a 3-dimensional (3D) image with an augmented reality device. Matching images of a 2D image database with the captured 3D-image, the 2D image database containing 2-dimensional (2D) images associated with points of interest having a 2-dimensional (2D) data set. When the 2D-image matches the 3D image, capturing 3D-data for the matched 2D-image and converting the 2D-data set of the point-of-interest to a 3D-data set. The disclosed method simplifies the configuration of points of interest for 3D applications, such as an augmented reality device.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: July 27, 2021
    Assignee: Schneider Electric Industries SAS
    Inventors: Thierry Chiche, Romain Gassion
  • Patent number: 11071443
    Abstract: Minimizing image sensor input/output pads in a pulsed laser mapping imaging system is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a plurality of bidirectional pads comprising an output state for issuing data and an input state for receiving data. The system includes a controller configured to synchronize timing of the emitter and the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises a laser mapping pattern.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: July 27, 2021
    Inventors: Joshua D. Talbert, Donald M. Wiehern
  • Patent number: 11074690
    Abstract: A method of enhancing the visibility of blood vessels in a colour image captured by an image capturing device of a medical device, including, for at least some of the pixels of the image, the steps of: (a) processing data obtained from a first colour channel together with data obtained from a second colour channel to determine a value of a first parameter indicative of the intensity in the red spectrum relative to the total intensity of said pixel; (b) using said value of said first parameter and a first value of a user parameter to alter said pixel, the first value of the user parameter being based on user input, and wherein the strength of the alteration is dependent on both the value of said first parameter and the first value of said user parameter.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: July 27, 2021
    Assignee: AMBU A/S
    Inventors: Andreas Härstedt Jørgensen, Finn Sønnenborg
  • Patent number: 11054565
    Abstract: An optical scanning apparatus including: an optical fiber that is configured to guide light from a light source to emit the light from a distal end thereof; a driver that is configured to oscillate the distal end of the optical fiber at a driving frequency in a direction intersecting a longitudinal axis of the optical fiber; a resonance-frequency detector that is configured to detect a resonance frequency of the distal end of the optical fiber; and a driving-frequency adjustor that is configured to adjust the driving frequency so that the ratio between the resonance frequency detected by the resonance-frequency detector and the driving frequency becomes constant.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: July 6, 2021
    Assignee: OLYMPUS CORPORATION
    Inventors: Atsuyoshi Shimamoto, Soichiro Koshika
  • Patent number: 11039956
    Abstract: An ophthalmological laser therapy device including a laser system, an x-y scanner, collecting optics and a z-scanner. The invention also relates to a method for processing a tissue of an eye by a therapeutic laser beam of an ophthalmological laser therapy device. The invention provides an ophthalmological laser therapy device and a corresponding method which permit, with minimal engineering complexity, a very quick positioning of the laser spot in a large volume region, in particular in a large x-y region perpendicular to the optical axis. The problem is also solved by a method for processing a tissue of the eye or a material located in an eye using an ophthalmological laser therapy device, wherein each sub-section of the tissue of the eye is processed using a corresponding positioning or the device for the adjustable redirecting of the laser beam in an image field of the collection optics.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: June 22, 2021
    Assignee: Carl Zeiss Meditec AG
    Inventors: Beate Böhme, Marco Hanft, Thomas Nobis
  • Patent number: 11035733
    Abstract: Chromatic calibration of a device having an embedded camera proceeds by illuminating a plurality of color references with at least one light source. Images of the respective illuminated color references are captured with the embedded camera. Color calibration data from are determined from the captured images and the color calibration data are stored in association with an identifier of the device.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: June 15, 2021
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Mahbubunnabi Tamal, Maram Abdullah Alqarni, Danah Naif Alotaibi, Meernah Mohammed Alabdullah, Mona Ameen Alhawaj, Fatimah Najib Alsafwani, Noor Sami Alhawaj
  • Patent number: 11013412
    Abstract: A biological component measuring apparatus may include: a first light source configured to emit a first light of a first wavelength range onto an object; a second light source configured to emit a second light of a second wavelength range onto the object, the second wavelength range being different from the first wavelength range; a detector configured to detect the first light and the second light which are scattered from the object; and a processor configured to determine a scattering coefficient based on the detected first light, obtain blood vessel depth information based on the detected second light, and measure a biological component by correcting the scattering coefficient based on the blood vessel depth information.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: May 25, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kun Sun Eom, Joon Hyung Lee, Jeong Eun Hwang, Jung Yong Nam, Ki Young Chang
  • Patent number: 11013436
    Abstract: In some examples, a medical system includes a medical device. The medical device may include a housing configured to be implanted in a target site of a patient, a light emitter configured to emit a signal configured to cause a fluorescent marker to emit a fluoresced signal into the target site, and a light detector that may be configured to detect the fluoresced signal. The medical system may include processing circuitry configured to determine a characteristic of the fluorescent marker based on the emitted signal and the fluoresced signal. The characteristic of the fluorescent marker may be indicative of a presence of a compound in the patient, and the processing circuitry may be configured to track the presence of the compound of the patient based on the characteristic of the fluorescent marker.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: May 25, 2021
    Assignee: MEDTRONIC, INC.
    Inventors: John E. Burnes, James K. Carney, Jonathan L. Kuhn, Mark J. Phelps, Jesper Svenning Kristensen, Rodolphe Katra
  • Patent number: 11010891
    Abstract: There are provided a medical image processing apparatus, an endoscope apparatus, a diagnostic support apparatus, and a medical service support apparatus capable of detecting red blood cells using an endoscope image. A medical image processing apparatus includes: a medical image acquisition unit that acquires short wavelength medical images, which are medical images including a subject image and which are obtained by imaging a subject with light in a shorter wavelength band than a green wavelength band; and a red blood cell detection unit that detects red blood cells using the short wavelength medical images. The light in the short wavelength band is, for example, light in a blue band or a violet band of a visible range. The red blood cell detection unit detects, for example, a high-frequency, granular, and high-density region as red blood cells.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: May 18, 2021
    Assignee: FUJIFILM Corporation
    Inventor: Hiroki Watanabe
  • Patent number: 11012599
    Abstract: Systems, methods, and devices for hyperspectral imaging in a light deficient environment are disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a controller comprising a processor in electrical communication with the image sensor and the emitter, wherein the controller synchronizes timing of the pulses of electromagnetic radiation during a blanking period of the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, electromagnetic radiation having a wavelength from about 565 nm to about 585 nm, or electromagnetic radiation having a wavelength from about 900 nm to about 1000 nm.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: May 18, 2021
    Assignee: Ethicon LLC
    Inventors: Joshua D. Talbert, Donald M. Wichern
  • Patent number: 10993620
    Abstract: A method for locating a functional brain tissue by electrical stimulation includes performing electrical stimulations of different areas of the brain tissue to activate brain tissue regions identifying the functional brain tissue, recording an image or a video sequence of the brain tissue during and/or after a stimulation, comparing the recorded image or the video sequence with a reference image or a reference video sequence recorded without stimulation to determine a position of the brain tissue region that is activated by the stimulation. At least two stimulations of a plurality of electrical stimulations are performed, one directly after the other or simultaneously, and the recording of an image or a video sequence of the portion of brain tissue takes place during and/or after each performance of one of the at least two stimulations or during and/or after the simultaneous performance of the at least two stimulations.
    Type: Grant
    Filed: September 28, 2019
    Date of Patent: May 4, 2021
    Assignee: Carl Zeiss Meditec AG
    Inventors: Tobias Meyer, Martin Oelschlaegel, Ute Morgenstern, Stephan B. Sobottka, Gabriele Schackert
  • Patent number: 10993607
    Abstract: An endoscope apparatus and a method of operating the endoscope apparatus that perform both illumination light observation and fluorescence observation by a simple configuration. At least a part of a wavelength region of excitation light is included in a first wavelength region where the absorption intensity of a fluorescent material is 10% or more of a first peak value. The wavelength region of the excitation light is included in a second wavelength region where the transmittance of a first spectral transmittance characteristic is 60% or more of a second peak value and a third wavelength region where the transmittance of a second spectral transmittance characteristic is 40% or less of a third peak value. A wavelength at which intensity of fluorescence is a peak is included in a fourth wavelength region where the transmittance of the second spectral transmittance characteristic is 80% or more of the third peak value.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: May 4, 2021
    Assignee: FUJIFILM Corporation
    Inventors: Toshihiko Omori, Makoto Sugizaki
  • Patent number: 10989910
    Abstract: Medical imaging camera head devices and methods are provided using light captured by an endoscope system or other medical scope or borescope. Afocal light from the scope is manipulated and split. The resulting first and second beams are passed through focusing optics to a single sensor. To take better advantage of the available number image sensor pixels, the beam may pass through lens elements (or prisms) to generate an anamorphic aspect ratio prior to being split, increasing the resolution of the image in one dimension. The afocal anamorphic beam is then split, and both images are focused on the image sensor. The anamorphism is compensated for in image processing, permitting higher resolution in one dimension along the image sensor. The manipulation of the beams prior to being split (and in some cases after or while being split) can take several forms, each offering distinct advantages over existing systems.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: April 27, 2021
    Assignee: KARL STORZ Imaging, Inc.
    Inventors: George E. Duckett, III, Marios Kyperountas
  • Patent number: 10983336
    Abstract: A dome cover for covering a camera, the dome cover includes a spherical part and an aspherical part. The spherical part and the aspherical part have a boundary, where the spherical part and the aspherical part are adjacent to each other, on each of a front surface and a back surface of the dome cover. The aspherical part has a shape symmetrical with respect to a rotation around a rotation axis including a center of a sphere of the spherical part. On a section including the rotation axis, a distance from the rotation axis to the aspherical part increases as a position of the aspherical part becomes more distant from the boundary, an angle formed between the rotation axis and a line segment connecting the center of the sphere and the boundary on the front surface is less than 90°. A predetermined condition is satisfied.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: April 20, 2021
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Hirofumi Abe, Kenta Sudo
  • Patent number: 10980458
    Abstract: A used photoacoustic apparatus includes: a light source capable of individually emitting light having a first wavelength at which absorption coefficients of oxyhemoglobin and deoxyhemoglobin are equal and light having a second wavelength; an acoustic detector that receives acoustic waves generated when the light having the first and second wavelengths is absorbed by an object; an absorption coefficient distribution generator that determines absorption coefficient distributions of an object interior; a blood vessel position determining unit that determines a blood vessel position from an absorption coefficient distribution corresponding to the first wavelength; an organism characteristics distribution calculator that determines an organism characteristics distribution from the absorption coefficient distributions; and a trimming unit that trims the organism characteristics distribution in accordance with the blood vessel position.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: April 20, 2021
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Yoshiko Wada, Takuji Oishi
  • Patent number: 10984910
    Abstract: A system for confirmation of fluid delivery to a patient at the clinical point of use is provided. The system includes a wearable electronic device. The wearable electronic device has a housing; at least one imaging sensor associated with the housing; a data transmission interface; a data reporting accessory for providing data to the user; a microprocessor for managing the at least one imaging sensor, the data transmission interface, and the data reporting accessory; and a program for acquiring and processing images from the at least one imaging sensor. The system further includes a fluid delivery apparatus; and one or more identification tags attached to or integrally formed with the fluid delivery apparatus. The program processes an image captured by the at least one imaging sensor to identify the one or more identification tags and acquires fluid delivery apparatus information from the one or more identification tags.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: April 20, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Jonathan Karl Burkholz, Jeff O'Bryan
  • Patent number: 10982947
    Abstract: A system and method for surface inspection of an object using multiplexed optical coherence tomography (OCT) is provided. The method includes moving the object relative to two or more scanner heads along a direction of travel; alternatingly directing a sample beam to each of the two or more scanner heads; and when the sample beam is directed at each respective scanner head, scanning comprising: steering the sample beam from the respective scanner head to an unscanned region on the surface of the object; and performing an A-scan of the object.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: April 20, 2021
    Assignee: Sightline Innovation Inc.
    Inventors: Wallace Trenholm, Lorenzo Pons
  • Patent number: 10979646
    Abstract: Systems, methods, and devices for fluorescence imaging with a minimal area image sensor are disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation, wherein the pixel array comprises active pixels and optical black pixels. The system includes a black clamp circuit providing offset control for data generated by the pixel array and a controller comprising a processor in electrical communication with the image sensor and the emitter. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 795 nm to about 815 nm.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: April 13, 2021
    Assignee: Ethicon LLC
    Inventors: Joshua D. Talbert, Donald M. Wichern
  • Patent number: 10966590
    Abstract: There is provided a surgical system including a monitoring sensor configured to sense a characteristic of a surgical site within a body, in a sensing region of the surgical site which includes at least a part of a region outside a display field of an endoscope, and circuitry configured to detect an occurrence of a medical abnormality in the region outside the display field of the endoscope based on a result of the sensing by the monitoring sensor, and generate notification information regarding the detected medical abnormality.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: April 6, 2021
    Assignee: SONY CORPORATION
    Inventors: Yasuaki Takahashi, Tomoyuki Hirayama, Hiroshi Ichiki, Masahito Yamane, Yuki Sugie, Hisakazu Shiraki
  • Patent number: 10959608
    Abstract: Provided is a fluorescence imaging device comprising: a light source for irradiating a subject with a laser for exciting a fluorescent dye; a condensing lens that receives light from the light source, an endoscopic probe comprising an image fiber and a lens that is disposed on the distal end of the image fiber; a photodetector that detects return light from the subject; and an oscillating element that is connected to the image fiber or the condensing lens and that, upon application of a voltage, causes the image fiber or the condensing lens to oscillate. With this configuration, a lattice pattern of fiber elements, which appears in an image of a subject, can be cancelled in real time by oscillating the oscillating element.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: March 30, 2021
    Assignee: TOHOKU UNIVERSITY
    Inventors: Makoto Osanai, Hajime Mushiake
  • Patent number: 10962414
    Abstract: Speckle contrast method and system that discriminates photons based on their path length in tissue, the method comprising the steps of: directing light from a pulsed light into a sample by optical elements; synchronizing the time between the pulse injection to sample and the detection unit; collecting the photons that have travelled through the sample by optics, and conveying the photons of a single or a limited number of speckles from the sample to one or more detection elements; time-tagging photons thanks to the synchronization of the detector element and/or the time-tagging electronics with the laser pulse emission; estimating each photon time-of-flight by the difference between its time tag and the laser pulse emission; categorizing the detected photons based on the value of the time-of-flight in a certain number of time gates; measuring the speckle contrast.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: March 30, 2021
    Assignees: FUNDACIÓ INSTITUT DE CIÈNCIES FOTÔNIQUES, CASTELLDEFELS, INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS
    Inventors: Turgut Durduran, Ernesto Vidal Rosas, Marco Pagliazzi
  • Patent number: 10952638
    Abstract: A method and system for monitoring respiratory rate of a patient is provided. An example system includes a wearable device configured to be disposed around a wrist of the patient. The wearable device may include a gyroscope to measure a gyroscope signal indicative of a motion of the patient. The system may further include a processor communicatively coupled to the gyroscope. The processor can be configured to perform a spectral analysis of the gyroscope signal to obtain a spectrum in a pre-determined range. The pre-determined range may cover a normal respiratory rate range. The processor can be further configured to determine a position of a peak in the spectrum to obtain a value for the respiratory rate. The processor can be further configured to provide, based on the value of the respiratory rate, a message regarding a health status of the patient.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: March 23, 2021
    Assignee: ChroniSense Medical Ltd.
    Inventor: Daniel H. Lange
  • Patent number: 10939878
    Abstract: An overdose of opioids can cause the user to stop breathing, resulting in death. A physiological monitoring system monitors respiration based on oxygen saturation readings from a fingertip pulse oximeter in communication with a smart mobile device and sends opioid monitoring information from the smart mobile device to an opioid overdose monitoring service. The opioid overdose monitoring service notifies a first set of contacts when the opioid monitoring information.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: March 9, 2021
    Assignee: Masimo Corporation
    Inventors: Massi Joe E. Kiani, Bilal Muhsin, Ammar Al-Ali, Keith Ward Indorf, Omar Ahmed, Jerome Novak, Walter M. Weber
  • Patent number: 10939802
    Abstract: An optical device may include an optical fiber having a fixed end and a free end; a first actuator positioned at a actuator position between the fixed end and the free end and configured to apply a first force on the actuator position of the optical fiber such that a movement of the free end of the optical fiber in a first direction is caused, wherein the first direction is orthogonal to a longitudinal axis of the optical fiber; and a deformable rod disposed adjacent to the optical fiber, and having a first end and a second end, wherein the first end is connected to a first rod position of the optical fiber and the second end is connected to a second rod position of the optical fiber.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: March 9, 2021
    Assignee: VPIX Medical Incorporation
    Inventors: Kyungmin Hwang, Jeong Ho Lee, Koun Hee Lee, Ki Hun Jeong
  • Patent number: 10939811
    Abstract: A light source device for endoscope includes a rotational body configured to rotate with a rotational axis as a center; a fluorescent body arranged in a predetermined area of the rotational body and configured to generate fluorescence by excitation light being radiated; an illuminating portion capable of selectively radiating excitation light of a first quantity and excitation light of a second quantity which is larger than the first quantity to a fluorescent body; and a control portion configured to switch between a first state of radiating the excitation light of the first quantity to the fluorescent body arranged in a first area and a second state of radiating the excitation light of the second quantity to the fluorescent body arranged in a second area.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: March 9, 2021
    Assignee: OLYMPUS CORPORATION
    Inventors: Yusuke Yabe, Satoshi Tanaka, Tomoya Takahashi, Masaaki Watanabe, Susumu Hashimoto, Yasuo Komatsu, Manabu Yajima, Akihiko Mochida, Koji Omori
  • Patent number: 10937163
    Abstract: An image capturing device used to capture an image of an object is provided. The image capturing device includes a camera, a first light source and a controller. The first light source is disposed adjacent to the camera. The controller is electrically connected to the camera and the first light source and is configured to: control the camera to capture a first picture of the object under the condition that the first light source does not emit any light; control the camera to captures a second picture of the object under the condition that the first light source emits a light; subtract the first picture from the second picture to filter off the background brightness of the second picture to obtain a first filtered picture; and analyze the first filtered picture to obtain a probability of the object matching a certain state.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: March 2, 2021
    Inventors: Jung-Wen Chang, Chien-Hung Lin
  • Patent number: 10932648
    Abstract: An image processing apparatus includes a processor comprising hardware. The processor is configured to: acquire a movement amount of a capsule endoscope in a movement direction of the capsule endoscope, based on information transmitted from the capsule endoscope including an imaging sensor; and determine whether to associate a first image captured by the imaging sensor with a second image, which is captured by the imaging sensor and is captured at a time different from a time in which the imaging sensor captures the first image, based on an imaging distance of the imaging sensor in the movement direction, and the movement amount.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: March 2, 2021
    Assignee: OLYMPUS CORPORATION
    Inventor: Kei Mitsuhashi
  • Patent number: 10925511
    Abstract: A system for determining cardiac targets is provided. The system may include at least one processing device configured to carry out instructions to receive cardiac imaging data, segment the cardiac imaging data to identify at least two types of cardiac tissue, generate a cardiac model based on the identified tissue, simulate cardiac activity based on the generated cardiac model, and identify at least one cardiac target based on the simulation. A cardiac therapy system may be utilized to provide feedback to a user in order to guide a cardiac treatment device to a cardiac target.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: February 23, 2021
    Assignee: CardioSolv Ablation Technologies, Inc.
    Inventors: Robert Blake, Scott Kokones, Brock Tice
  • Patent number: 10921244
    Abstract: Methods and systems may be used for measuring fluid status in a subcutaneous tissue space. Systems may include a wearable device or a diagnostic tool. The device may include a processor, an emitter, and a detector. The emitter and the detector are coupled to the processor. The emitter may be configured to emit a signal into a subcutaneous tissue space of a subject. The signal may be reflected by the subcutaneous tissue space. The detector may be configured to receive the reflected signal. The processor may be configured to determine a fluid status in the subcutaneous tissue space. The fluid status in the subcutaneous tissue space may be based on an energy level of the reflected signal.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: February 16, 2021
    Assignee: Spectroflow, Inc.
    Inventors: Stephen Zadig, Dan Eric Buffkin, Jr., Michael Dillhyon
  • Patent number: 10912583
    Abstract: An access port is disclosed for use in minimally invasive surgical procedures performed within a patient's abdominal cavity, which includes a body defining a bore configured to guide at least one surgical instrument into the abdominal cavity, and concave and convex anchoring regions for securing the access port relative to the abdominal cavity.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: February 9, 2021
    Assignee: Axcess Instruments Inc.
    Inventors: Michael J. Norton, Noel D. Ischy
  • Patent number: 10905331
    Abstract: An image capturing device and a sensing protection device are provided. The image capturing device includes a light source configured to emit lights on a skin, an image sensor configured to obtain an image of the skin from lights reflected from the skin, a sensing protection device, which is an attachable and detachable, configured to surround the light source and the image sensor and includes a connection unit configured to be attached to and detached from the image capturing device, and a controller configured to process characteristics of the skin based on the obtained image.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: February 2, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Maxim Alexeevich Vilenskii
  • Patent number: 10905317
    Abstract: Provided is a fluorescence imaging device comprising: a light source for irradiating a subject with a laser for exciting a fluorescent dye; a condensing lens that receives light from the light source, an endoscopic probe comprising an image fiber and a lens that is disposed on the distal end of the image fiber; a photodetector that detects return light from the subject; and an oscillating element that is connected to the image fiber or the condensing lens and that, upon application of a voltage, causes the image fiber or the condensing lens to oscillate. With this configuration, a lattice pattern of fiber elements, which appears in an image of a subject, can be cancelled in real time by oscillating the oscillating element.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: February 2, 2021
    Assignee: TOHOKU UNIVERSITY
    Inventors: Makoto Osanai, Hajime Mushiake
  • Patent number: 10898080
    Abstract: The present invention discloses a microcirculation shock monitor enabling rapid and repeated positioning, a monitoring system and a monitoring method, belonging to the technical field of microcirculation shock monitoring. By the present invention, the same blood vessel in the same monitored area can be repeatedly positioned and monitored quickly within different periods of time, and blood vessel image data can be acquired, and then, on this basis, qualitative analysis or quantitative analysis is performed to obtain related monitored data, where quantitative analysis parameters comprise a high-speed blood flow intensity ratio R, a high-speed blood flow spreading rate S, a high-speed blood flow intensity duration T and a difference D of abnormal change in high-speed blood flow intensity of a monitored object, which facilitates studies and lays an accurate data foundation for rapidly indicating early and middle stage indications of infectious shock in a next step.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: January 26, 2021
    Inventor: Xinghuai Feng
  • Patent number: 10900835
    Abstract: Disclosed are hyperspectral/multiple spectral imaging methods and devices. A method obtains first and second spectral image datasets of a region of interest (ROI). The first spectral image dataset is characterized by a first spectral range and the second spectral image dataset is characterized by a second spectral range. The method then performs a first spectral analysis on the first spectral image dataset and a second spectral analysis on the second spectral image dataset. Afterwards, the method determines one or more spectral signature(s) at a deeper layer of the ROI.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: January 26, 2021
    Assignee: HYPERMED IMAGING, INC.
    Inventors: Mark Anthony Darty, Peter Martin Meenen
  • Patent number: 10885667
    Abstract: Disclosed a normalized metadata generation device, and object occlusion detection device and method. A normalized metadata generation method includes generating a multi-ellipsoid based three-dimensional human model using perspective features of a plurality of two-dimensional images obtained by the multiple cameras, performing scene calibration based on the three-dimensional human model to normalize object information of the object included in the two-dimensional images, and generating normalized metadata of the object from the two-dimensional images on which the scene calibration is performed.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: January 5, 2021
    Assignee: CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
    Inventors: Joon Ki Paik, Jae Hoon Jung, In Hye Yoon, Seung Won Lee
  • Patent number: 10881273
    Abstract: A pre-fabricated, on-demand interface provides optical coupling between disposable and reusable portions of a fiber-optic probe. The interface uses a pre-cured, compressible optically-transmissive gel in a cavity of the disposable portion, which can be a disposable insertion tip of the fiber optic probe. The disposable portion includes an elongated housing, or sheath, and the cavity is located within and proximal of a distal end of the elongated housing. A proximal end of an optical assembly of the disposable portion is located within the cavity and contacts the gel. A first coupling, provided at a proximal end of the elongated housing, detachably couples to a mating, second coupling of the probe reusable portion. When the disposable and reusable portions are coupled together, the gel is compressed between the proximal end of the optical assembly of the disposable portion and a distal optical member of an optical assembly of the reusable portion.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: January 5, 2021
    Assignees: Northwestern University, American Biooptics LLC
    Inventors: Vadim Backman, Bradley Gould, Andrew J. Cittadine, Nikhil Mutyal
  • Patent number: 10881350
    Abstract: A physiological signal measurement device includes a housing, a bracket, a rigid circuit board fastened in the housing, a first flexible circuit board assembled in the housing and the in-ear portion, and a protective sleeve. The housing protrudes frontward to form an in-ear portion. The bracket has a base portion fastened to the in-ear portion. Several portions of a front surface of the base portion protrude frontward to form a plurality of first elastic portions. The first flexible circuit board has a resilient end. The resilient end of the first flexible circuit board surrounds the plurality of the first elastic portions. The protective sleeve has a fastening portion, and a plurality of spaced second elastic portions protruded from the fastening portion. The plurality of the spaced second elastic portions surround the plurality of the first elastic portions and the resilient end of the first flexible circuit board.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: January 5, 2021
    Assignee: CHENG UEI PRECISION INDUSTRY CO., LTD.
    Inventors: Sheng-Chieh Lo, Peng-Yuan Lee, Chih-Yuan Lu
  • Patent number: 10877254
    Abstract: A light sheet microscope for simultaneous imaging of several object planes illuminated by a light sheet includes a camera and a detection optic defining a detection light beam between the light sheet and the camera. The object planes are arranged around the focal plane of the detection optic. The detection optic can include a microlens array.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: December 29, 2020
    Assignee: LEICA MICROSYSTEMS CMS GMBH
    Inventors: Werner Knebel, Florian Fahrbach
  • Patent number: 10856722
    Abstract: Provided are an image processing apparatus and an electronic endoscope system that can acquire an observation image that is natural overall and has excellent visibility, while highlighting characteristic parts such as affected parts and parts that are to be examined. A normal observation image captured using normal light and a narrow-band observation image captured using narrow-band light that has a bandwidth narrower than that of normal light are input to the observation image input unit. A characteristic part extraction unit extracts a characteristic part that is included in a narrow-band observation image. A highlight display unit displays a single image in which a part of the normal observation image, the part corresponding to a characteristic part that is included in the narrow-band observation image, is highlighted using the characteristic part.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: December 8, 2020
    Assignee: HOYA CORPORATION
    Inventor: Takao Makino
  • Patent number: 10849506
    Abstract: A system and a method for improving visibility of newly decaying or carious tissue are described. Light having a lower peak wavelength (such as 405 nm) illuminates dental tissue, and an image is captured. Light having a higher peak wavelength (such as 450 nm) then illuminates the same dental tissue, and a second image is captured. The images are aligned, and an output image is created based on at least one of the first image and the second image, modified in certain areas as a function of the relationships between the red values of the first image (R1) and the second image (R2) at that location and the green values of the first image (G1) and the second image (G2) at that location. The function may use the ratios R2:R1 and G1:G2, such as a function of the product of those ratios, to determine the color adjustment that is applied.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: December 1, 2020
    Assignee: INSPEKTOR RESEARCH SYSTEMS B.V.
    Inventor: Elbert de Josselin de Jong
  • Patent number: 10852434
    Abstract: A depth camera assembly (DCA) determines distances between the DCA and objects in a local area within a field of view of the DCA. The DCA projects a series of sinusoidal patterns each having different wavelengths into the local area DCA and captures images of the sinusoidal patterns via a sensor. Optical filters configured to pass different wavelengths of light are positioned within the sensor to form regions including adjacent pixels. Hence, pixels in a region capture light having a wavelength passed by an optical filter corresponding to the region. If the DCA projects sinusoidal patterns having different wavelengths at different times, the sensor is gated with an illumination source so regions of the sensor capturing light having a specific wavelength capture light while the illumination source emits the specific wavelength and not while the illumination source emits other wavelengths.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: December 1, 2020
    Assignee: Facebook Technologies, LLC
    Inventors: Michael Hall, Qing Chao
  • Patent number: 10849505
    Abstract: An electronic microscope has an electronic image sensor for generating primary image data sets, wherein the image sensor is configured to generate image signals that correspond to a plurality of different reception spectra, and wherein each primary image data respectively comprises at least one image signal of each of the plurality of reception spectra for a plurality of image zones. A control device of the microscope is configured to control an illumination device to make a cyclically repeating transmission of electromagnetic radiation having a plurality of different illumination spectra and to control the image sensor to generate a respective primary image data set for each of the plurality of different illumination spectra.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: December 1, 2020
    Assignee: ARNOLD & RICHTER CINE TECHNIK GMBH & CO. BETRIEBS KG
    Inventors: Julius Muschaweck, Hans Kiening, Patrick Burckstummer, Peter Geissler
  • Patent number: 10847563
    Abstract: A wearable system includes a stacked photodetector assembly including a first wafer including a single photon avalanche diode (SPAD), the first wafer having a thickness T1 configured to minimize absorption by the first wafer of photons included in light incident upon the first wafer while the SPAD is in a disarmed state, and a second wafer having a thickness T2 including a fast gating circuit electrically coupled to the SPAD and configured to arm and disarm the SPAD, the second wafer bonded to the first wafer in a stacked configuration. The fast gating circuit includes a capacitor configured to be charged, while the SPAD is in the disarmed state, with a bias voltage by a voltage source, and supply, while the SPAD is in an armed state, the bias voltage to the SPAD such that a voltage across the SPAD is greater than a breakdown voltage of the SPAD.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: November 24, 2020
    Assignee: HI LLC
    Inventors: Ryan Field, Husam Katnani, Bruno Do Valle, Rong Jin, Jacob Dahle
  • Patent number: 10835111
    Abstract: The disclosed subject matter includes devices and systems for extending the imaging capability of swept, confocally aligned planar excitation (SCAPE) microscopes to in vivo applications. In embodiments, the SCAPE microscope can be implemented as an endoscopic or laparoscopic inspection instrument.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: November 17, 2020
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Elizabeth Marjorie Clare Hillman
  • Patent number: 10827914
    Abstract: An endoscope system generates first to third color image data by imaging biological tissue illuminated with first to third light. The endoscope system uses a first light intensity ratio of the first light and the second light, and/or an imaging sensitivity of the image sensor, to correct a first ratio between multiple components of the first and second color image data, and the endoscope system calculates a first characteristic amount of the biological tissue based on the first corrected ratio. Furthermore, the endoscope system uses a second light intensity ratio between the second light and the third light to correct a second ratio between multiple components of the second and third color image data, and the endoscope system calculates a second characteristic amount of the biological tissue based on the second corrected ratio and the first characteristic amount.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: November 10, 2020
    Assignee: HOYA CORPORATION
    Inventor: Masaaki Fukuda
  • Patent number: 10828198
    Abstract: Systems and techniques for laser surgery are described. Scan data may be created by determining a coordinate of the object at a set of points along an arc by the imaging system, wherein the coordinate of the object is a Z coordinate of an object layer. An object shape parameter and position parameter may be determined based on the scan data by a system control module by extracting an amplitude and a phase of the scan data determining a center of the object layer based on the extracted amplitude and phase.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: November 10, 2020
    Assignee: Alcon Inc.
    Inventors: Ilya Goldshleger, Guy Holland, Ferenc Raksi
  • Patent number: 10820788
    Abstract: A capsule endomicroscope has a predetermined axial length and a diameter smaller than the axial length. The endomicroscope can acquire images of a surface of a hollow organ, and includes a microscopic image acquisition assembly having an optical axis oriented in a radial direction of the endomicroscope to acquire microscopic images of a section of the surface of a hollow organ present in a predetermined image acquisition area on a radial outer surface of the endomicroscope through a housing of the endomicroscope that has sectionally light-transparent material. A light source emits light rays in a radial direction through the light-transparent material of the housing during image acquisition. The light source and the light-transparent material of the housing located between the light source and the predetermined image acquisition area are interconnected to each other such that no refraction interface exists between the light source and the image acquisition area.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: November 3, 2020
    Assignee: OVESCO ENDOSCOPY AG
    Inventors: Sebastian Schostek, Alyssa Albiez, Marc O. Schurr
  • Patent number: 10818010
    Abstract: The present invention relates to a device, system and method for skin detection. To enable a reliable, accurate and fast detection the proposed device comprises an input interface (30) for obtaining image data of a scene, said image data comprising a time sequence of image frames, an extraction unit (31) for extracting a photoplethysmography (PPG) signal from a region of interest of said image data, a transformation unit (32) for transforming said PPG signal into a spectral signal, a sorting unit (33) for sorting said spectral signal to obtain a sorted spectral signal representing a descriptor, and a classifier (34) for classifying said region of interest as skin region of a living being or as non-skin region based on the descriptor.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: October 27, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Wenjin Wang, Gerard De Haan
  • Patent number: 10809187
    Abstract: The invention presents methods of using Fourier transform infrared (FTIR) microspectroscopy for common and specific characterization of carcinogenesis in human skin tumors. The invention provides the user with the method to analyse intra- and inter-molecular interactions for nucleic acids and proteins expressed in infrared (IR) spectra of human skin epidermal cancers towards understanding the molecular, cellular and tissue changes that occur during skin carcinogenesis. More particularly, presented analytical method has the advantage to simultaneously observe DNA-RNA, DNA-DNA, DNA-protein and protein-protein interactions by means of their expressed interacting activity levels within one type of tumour and between different types of tumours, both commonly and specifically, with further indication of the grade of activity in benign, premalignant and malignant skin tissue cells.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: October 20, 2020
    Inventor: Natalja Eikje
  • Patent number: 10810788
    Abstract: The present invention relates to a multichannel head assembly for a three-dimensional modeling apparatus which can improve productivity by simultaneously or synchronously modeling a plurality of three-dimensional shaped objects having the same shape or different shapes, and a three-dimensional modeling apparatus using the same, the present invention comprising: a modeling light source unit for allowing N modeling beams to be incident to a light guide unit; the light guide unit for receiving the N incident modeling beams and having a function of guiding each of the N modeling beams along a predetermined path so as to allow the N modeling beams to be incident to N modeling planes in one-to-one correspondence with each other; and a control unit for controlling driving of the modeling light source unit and driving of the light guide unit to be linked with each other.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: October 20, 2020
    Assignee: Korea Institute of Industrial Technology
    Inventors: Seung Taek Kim, Jong Seok Kim, Hyung Tae Kim, Kyung Chan Jin, Moon Soo Park