Having Structure For Controlling Depth Of Insertion Of Body Piercer Patents (Class 604/117)
  • Patent number: 11992037
    Abstract: A culinary injection delivery device including a cylindrical housing having an interior volume. The cylindrical housing is opened at both ends. The first opened end has a delivery nozzle attached thereto. The second opened end has a plunger located therein. The plunger is made up of a stick and at least two disks. A first disk located on an end of the stick and a second disk located slightly aft of the first disk. A spring located be the first and second disk is configured to push the first disk forward. The first disk has an extension placed thereon that matches the interior of the delivery nozzle. The spring will push the first disk forward releasing a food product.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: May 28, 2024
    Inventors: Nicole M. Gant, Dwane C. Gant
  • Patent number: 11938309
    Abstract: A hypodermic interface assembly is disclosed. The hypodermic interface assembly includes a hub, a cannula, and a cannula carrier. The cannula carrier is non-removably-connected to the cannula. The cannula carrier is controllably separable from the hub.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: March 26, 2024
    Inventors: Gregory S. Hastings, Bradley E. Galbreath, Nicholas J. Wagner, Taylor Kopacka Leigh, Peter Wyndham Shipp, Jr., Jason Lye, Randall M. Bachtel, Dexter E. Jacobs, Michael Trovato
  • Patent number: 11931067
    Abstract: A tissue guard includes an elongated body having a proximal end and a distal end and defining a lumen therethrough. A plurality of torsion springs is included, each torsion spring having a first leg and a second leg and a spring defined therebetween. The first leg of each torsion spring is operably engaged to the distal end of the elongated body. Two or more petals extend from the distal end of the elongated body, each petal is operably engaged to the second leg of one of the torsion springs. The petals are movable between a first, compressed configuration wherein the petals are compressed relative to one another against the bias of the plurality of torsion springs to facilitate insertion of the tissue guard within an access device or natural orifice and a second, expanded configuration to facilitate engagement of the petals beneath the access device or within the natural orifical to secure the tissue guard therein.
    Type: Grant
    Filed: August 11, 2021
    Date of Patent: March 19, 2024
    Assignee: Covidien LP
    Inventors: Jacob C. Baril, Saumya Banerjee
  • Patent number: 11896790
    Abstract: A dilator that includes a shaft and a spirally-arranged protruding portion. The shaft includes a tapered section, a distal end section, and a body section. The spirally-arranged protruding portion includes spirally-arranged protruding sections provided on outer peripheral surfaces of each of the tapered section, the distal end section, and the body section, and gaps between adjacent spirally-arranged protruding sections along an axial direction of the shaft. At least one of a height t of the spirally-arranged protruding portion at a first location gradually decreases toward a distal end side and a height of the spirally-arranged protruding portion at a second location gradually decreases toward a proximal end side.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: February 13, 2024
    Assignee: ASAHI INTECC CO., LTD.
    Inventors: Yukihiro Fuseya, Marina Tsuzuku
  • Patent number: 11883067
    Abstract: A dilator that includes a hollow shaft including a tapered section having a diameter increasing from a distal end toward a proximal end, and a spirally-arranged protruding portion provided on an outer peripheral surface of the hollow shaft and including spirally-arranged protruding sections and gaps between adjacent spirally-arranged protruding sections along an axial direction of the hollow shaft. The spirally-arranged protruding portion includes an apex section having the greatest height from the outer peripheral surface in a transverse cross-section thereof, and a side surface section facing outward and extending from the apex section toward the outer peripheral surface. The side surface section includes an inclined surface inclined substantially linearly toward at least one of the distal and proximal end direction between the outer peripheral surface and the apex section in the transverse cross-section of the spirally-arranged protruding portion.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: January 30, 2024
    Assignee: ASAHI INTECC CO., LTD.
    Inventors: Yukihiro Fuseya, Marina Tsuzuku, Daisuke Kurita
  • Patent number: 11871963
    Abstract: Apparatuses, systems, and methods are provided for securing an intra-osseous device within a safety device to prevent stick injuries and to guide the removal of the intra-osseous device from the bone of a patient. A body of the safety device has a cavity that receives the intra-osseous device, and the cavity guides the removal of the intra-osseous device along a straight line to prevent injury during removal. The intra-osseous device is drawn past a lock feature that secures the intra-osseous device within the body such that a needle of the intra-osseous device is contained within a cavity of the body and cannot injure the patient, staff members, etc.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: January 16, 2024
    Assignee: Shippert Tech, LLC
    Inventor: Brian Shippert
  • Patent number: 11871977
    Abstract: The present disclosure pertains to devices and methods for diagnosis and treatment of biological tissue in which the tissue is accessed by a catheter through a working channel of an endoscope and in which the degree of extension of a distal tip of the catheter beyond a distal tip of the endoscope is controlled.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: January 16, 2024
    Assignee: CSA MEDICAL, INC.
    Inventors: Sean Forde, Sean Arthur McDermott, Brian Hanley
  • Patent number: 11819454
    Abstract: Assemblies for and methods of intraocular injection. An injector assembly includes a housing defining an internal chamber and having a slot on an external surface thereof; a cannula needle having a lumen and a cutout on an outer surface; a flexible arm having a proximal end affixed to the outer surface of the cannula needle and a distal end having a hook such that the hook is disposed within the cutout; a pushrod slidably disposed within the lumen; and a latch slidably disposed in the slot of the housing, the latch coupled to the pushrod such that translation of the latch causes translation of the pushrod to thereby eject an implant disposed within the lumen between the hook and pushrod.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: November 21, 2023
    Assignee: Inflammasome Therapeutics, Inc.
    Inventor: Martin Nazzaro
  • Patent number: 11813184
    Abstract: Benign prosthetic hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland. Treatment options for BPH include medication, surgery (e.g., removal of enlarged prostate tissue), and minimally invasive procedures (e.g., needle ablation, electrovaporization, thermotherapy, and stent insertion). Minimally invasive procedure is typically the preferred choice if medication is ineffective. Accordingly, disclosed herein are system and method for treating BPH using improved implant and delivery device. Certain embodiments of the delivery device can include: a camming barrel having a first groove at the distal end of the camming barrel; a sheath, located within a lumen of the camming barrel, for storing the implantable device; and a first cam follower coupled to the sheath.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: November 14, 2023
    Assignee: ZENFLOW, INC.
    Inventors: Marcel Song Sicotte, Shreya Mehta, Austin Michael Bly, Ronald J. Jabba
  • Patent number: 11805997
    Abstract: Devices and methods for performing a skin biopsy are discussed herein. The skin biopsy device provides for consistent depth and shape, such as by reducing or eliminating operator error or inter-operator variability by generating the same forces across multiple uses. The skin biopsy device can also eliminate puckering of wound closures by incorporating a fusiform blade (e.g., elliptical blade or a diamond-shaped blade). The skin biopsy device includes a casing, a firing pin, a retaining rod, and a blade. The retaining rod holds the blade or can attach to a punch biopsy. The firing pin generates and impacts the retaining rod with a force necessary to drive the blade a given depth into a target tissue to obtain a biological sample.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: November 7, 2023
    Assignee: Revedeon, LLC
    Inventor: Alexander Thomas Reid
  • Patent number: 11786130
    Abstract: There is described a pressure guidewire. It comprises a sensor housing and a sensor assembly embedded in the sensor housing and comprising a pressure sensor. There is a band to support the pressure sensor assembly, the band being embedded inside the sensor housing and fixed to the pressure sensor assembly for holding the pressure sensor inside the sensor housing.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: October 17, 2023
    Assignee: Opsens Inc.
    Inventor: Claude Belleville
  • Patent number: 11786396
    Abstract: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: October 17, 2023
    Assignee: ForSight Vision4, Inc.
    Inventors: Eugene de Juan, Jr., Yair Alster, Kathleen Cogan Farinas, K. Angela Macfarlane, Cary J. Reich, Randolph E. Campbell, Darren Doud, Signe Erickson, Mike Barrett, David Batten, Christina Skieller, Greg Stine
  • Patent number: 11707205
    Abstract: An integrated catheter placement system for placing a catheter in a vasculature of a patient. The system includes a system console with a tip location mode and an ultrasound mode viewable on a display, a magnetic assembly emanating a magnetic field, a tip location sensor designed to sense the magnetic field, and an ultrasound probe for ultrasonically imaging an internal portion of the patient. The magnetic field may provide magnetic field information for locating the magnetic assembly relative to the tip location sensor. The tip location sensor is designed to communicate the magnetic field information to the system console. The system console is designed to display an icon representative of a location of the magnetic assembly relative to the tip location sensor in the tip location mode.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: July 25, 2023
    Assignee: C. R. Bard, Inc.
    Inventors: Shayne Messerly, Matthew W. Bown, Eddie K. Burnside, Kelly J. Christian
  • Patent number: 11701470
    Abstract: A protective assembly includes a body for receiving the syringe; and a coupling device inside the body, rigidly connected to the barrel as regards to axial movement relative to the body. The coupling device includes an attaching element which can be either in an engaged state to axially fix the coupling device and the plunger rod, or in a release state in which the coupling device and the plunger rod are axially free relative to one another. The coupling device is axially movable in the body from a storage position to an injection position in which the needle extends beyond the body, and in which the attaching element can move towards the release state. The coupling device is axially movable in the body from the injection position towards a safety position, in which the needle is covered by the body.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: July 18, 2023
    Assignee: Becton Dickinson France
    Inventors: Frédéric Perot, Salim Bouyahiaoui, Gilles Bernède
  • Patent number: 11672905
    Abstract: An insertion mechanism for a drug pump includes an insertion mechanism housing; a sleeve; a rotational biasing member initially held in an energized state; a retraction biasing member and a hub connected to a proximal end of a needle, wherein the retraction biasing member is held initially in an energized state between the hub and the sleeve. The needle is inserted into a target tissue by the rotational biasing member and interaction between the hub and housing. Retraction of the needle is caused by decompressing or de-energizing of the retraction biasing member. A drug delivery pump includes an activation mechanism, a drive mechanism, a sterile access connection, and the insertion mechanism. Assembly and operation methods are provided.
    Type: Grant
    Filed: November 18, 2020
    Date of Patent: June 13, 2023
    Assignee: AMGEN INC.
    Inventors: Mark A. Destefano, Lawton Laurence, John C. Love, Ian B. Hanson, Paul F. Bente, IV
  • Patent number: 11633214
    Abstract: Disclosed herein are intraosseous access devices having various operating mechanisms, as well as methods of the intraosseous access devices. For example, an intraosseous access device includes, in some embodiments, a constant-torque spring assembly, a drive shaft, an intraosseous needle, and an interlock mechanism. The constant-torque spring assembly is disposed in a housing, and the drive shaft extends from the housing. The drive shaft is coupled to the constant-torque spring assembly. The intraosseous needle is coupled to the drive shaft. The intraosseous needle is configured for drilling through bone and providing intraosseous access to a medullary cavity of a patient. The interlock mechanism is configured to prevent rotation of the intraosseous needle and the drilling therewith until the interlock mechanism is disengaged.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: April 25, 2023
    Assignee: Bard Access Systems, Inc.
    Inventors: Daniel Pett, Daniel B. Blanchard, Eric W. Lindekugel, Joe Spataro, Ralph Sonderegger
  • Patent number: 11576659
    Abstract: A bone marrow aspiration device and related method includes an introducer assembly and an aspiration assembly to couple to the introducer assembly. The introducer assembly includes an introducer cannula having a proximal end and a distal end. The introducer cannula defines a lumen between the distal and proximal ends, the distal end being configured to penetrate bone of a patient. The aspiration assembly includes an aspiration cannula that is receivable in the lumen of the introducer cannula and that extends beyond the distal end of the introducer cannula. The aspiration cannula includes a port to aspirate bone marrow, the port being distal to the distal end of the introducer cannula. The aspiration device further includes a mechanism at the introducer assembly to move the introducer cannula and the aspiration cannula in tandem relative to a distal end of the mechanism when the aspiration cannula is positioned within bone.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: February 14, 2023
    Assignee: Cervos Medical LLC
    Inventor: Andrew McGillicuddy
  • Patent number: 11571523
    Abstract: A syringe and needle hub for a syringe has distal patient-facing side having a surface for contact with the subject's skin during injection. The contact surface is formed by a distal face of a post supporting a cannula and an outer collar surrounding the post. The axial distance between the distal face of the post and the distal face of the collar provided a contact surface with a radius of curvature to control the desired injection. The syringe barrel can have finger flanges extending outwardly where the flanges have a tactile member such as a dimple projecting from a proximal face of the flange and recess in a distal face of the flange.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: February 7, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Kevin Watts, Roger Hoeck, Lance Lee Jacobi, Amit Uday Limaye
  • Patent number: 11547843
    Abstract: A venous access port assembly having a housing base with a discharge stem, a cap, and an interior reservoir. The port assembly is provided with X-ray discernable indicia to identify an attribute of the assembly after its implantation and clearly appear on an X-ray of the patient in a manner informing the radiologist or technologist and the medical practitioner of that particular attribute. The indicia are cuts in a reservoir lining of radiopaque material such as metal where the cuts having narrow slot width are in the form of one or more sets of alphabetical letters such as “CT” in the lining's side wall or bottom wall.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: January 10, 2023
    Assignee: Innovative Medical Devices, LLC
    Inventor: Kenneth M. Zinn
  • Patent number: 11541190
    Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: January 3, 2023
    Assignee: Janssen Biotech, Inc.
    Inventors: Lorin Olson, Vaclav Vojan, Juergen E. Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
  • Patent number: 11534557
    Abstract: According to the invention a safety device for a pre-filled syringe comprises a substantially cylindrical and hollow support body and a hollow needle shield slideably arranged relative to the support body. The support body comprises at least one resilient arm and the hollow needle shield or a needle shield assembly comprises at least one curved actuation ramp. The curved actuation ramp protrudes in a lateral direction (L) perpendicular to a central axis (A) of the safety device. The curved actuation ramp comprises a first lateral dimension (L1) at a proximal end of the needle shield and a second lateral dimension (L2) exceeding the first lateral dimension (L1) at a distal end of the needle shield. The resilient arm engages the curved actuation ramp when the needle shield is slid relative to the support body.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: December 27, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Gareth Roberts, Chris Ward, Matthew Ekman
  • Patent number: 11511037
    Abstract: Systems and methods are provided for measuring depth, position, and/or angle of a cannula in a medical drug delivery device. In particular, a drug delivery device having a cannula is positioned adjacent to tissue, a voltage pulse is provided to the cannula, a charge is measured at an electrode in the drug delivery device, and the depth of penetration of the cannula is determined based in part on the charge at the first electrode. Systems and methods described herein can be used to determine subcutaneous insertion depth in a wearable bolus injector. In some implementations, insertion depth determination is achieved through capacitive sensors which measure needle depth in a drug delivery device.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: November 29, 2022
    Assignee: Analog Devices, Inc.
    Inventor: Shrenik Deliwala
  • Patent number: 11504482
    Abstract: A precision steerable and angled medication delivery system is disclosed. The system may direct a delivery mechanism in connection with a control syringe to delivery sites within a patient's body. In this manner, therapeutic injections may be performed at precise locations as desired. The precision steerable and angled medication delivery system may have a structure configured to orient at least a portion of an elongate penetrative feature such as needle to be at least partially non-parallel to a longitudinal axis, further facilitating performance of therapeutic injections at precise locations.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: November 22, 2022
    Inventor: Peter A. Sirianni
  • Patent number: 11484660
    Abstract: A force actuated injection device including a body adapted to contain medication, a grip slidably disposed over the body, a lock disposed between the body and the grip, the lock when locked preventing movement of the grip relative to the body and when unlocked permitting movement of the grip relative to the body, a needle guard retractable relative to the body, a biasing member biasing the needle guard away from the body, and a resistance band disposed between the body and the needle guard adapted to resist initial needle guard retraction relative to the body, wherein force on the needle guard exceeding a predetermined amount overcomes a frictional force of the resistance band allowing the needle guard to retract relative to the body to unlock the grip relative to the body such that movement of the grip relative to the body causes medication to be delivered from the body.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: November 1, 2022
    Assignee: Parenteral Technologies, LLC
    Inventor: Michael A. Creaturo
  • Patent number: 11457903
    Abstract: A needle or stylet has a tip contour with a reverse back bevel curved toward the longitudinal axis of the needle or stylet. The needle has a flexible intermediate portion and/or a two-part construction in which a distal portion of the needle to crimped onto a proximal portion of the needle. The needle or a stylet is combined with a spring mechanism in the hub of the needle or stylet assembly. The spring mechanism positions the tip of the needle or stylet in a middle position extending from the distal end of the assembly, allows the needle or stylet to be moved into a spring loaded fully retracted configuration within the assembly as the septal wall is tented, and then releasing the spring loaded needle or stylet as the needle or stylet penetrates the septal wall. A method of using a needle or stylet with a spring mechanism is included.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: October 4, 2022
    Assignee: Pressure Products Medical Supplies, Inc.
    Inventors: Paul Kurth, Andrew Armour, Reed Garrett, William Gallo
  • Patent number: 11445916
    Abstract: An insert according to the invention includes a needle tube that has an inclined surface having a leading end opening, a needle base that has a chamber communicating with an inside of the needle tube and holds the needle tube, and a light introduction portion that communicates with the chamber and has an insertion path into which a light guide member is inserted.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: September 20, 2022
    Inventor: Kaku Irisawa
  • Patent number: 11446177
    Abstract: Embodiments of the invention provide apparatus, systems and method for introducing fluids into a body cavity for treatment. One embodiment provides an apparatus for treating a patient including an access device for insertion into the peritoneal cavity of the patient including an infusion member in a lumen of the access device. An oxygenated solution may be infused and removed into and out of the cavity via the infusion member.
    Type: Grant
    Filed: March 23, 2022
    Date of Patent: September 20, 2022
    Assignee: TheraNova, LLC
    Inventors: Daniel R. Burnett, Shane Mangrum
  • Patent number: 11406705
    Abstract: The present disclosure provides methods, uses and compositions and kits for use in inducing an antibody immune response in a human subject. The methods and uses involve administering parenterally a low dose volume of a composition comprising an antigen comprising a B-cell epitope, an amphipathic compound, and a hydrophobic carrier, wherein the low dose volume of the composition is less than 100 ?l and induces an antibody immune response to the B-cell epitope in the human subject.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: August 9, 2022
    Inventors: Marc Mansour, Frederic Ors, Marianne Stanford, Leeladhar Sammatur, Rajkannan Rajagopalan, Lisa Diana MacDonald
  • Patent number: 11400238
    Abstract: A needle-bearing hub for a pen needle is provided with a distal patient-facing side having an enlarged surface for contact with the subject's skin. The enlarged surface is provided with a radius of curvature that increases the likelihood that the needle reaches full injection depth when an injection is performed at an inclined angle with respect to the surface of the skin and with to the desired depth less discomfort to the patient.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: August 2, 2022
    Assignee: Embecta Corp.
    Inventors: Sean Sullivan, David Huang, Brendon Hill, Sudarsan Srinivasan, Christopher Rini, Richard Klug, Bruce Clyde Roberts, Didier Morel, Ronald J. Pettis
  • Patent number: 11400270
    Abstract: A delivery adapter which may be used as an interface between a syringe and a catheter hub is described.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: August 2, 2022
    Assignee: MicroVention, Inc.
    Inventors: Pete Barker, Jonathan Lam, Scott Pool, Frida San, Edgar Villanueva
  • Patent number: 11389089
    Abstract: An inserter for a medical device, where the inserter includes a housing having a first end with an opening therein, an actuator connected to a first gear, an actuator biasing element, a cam gear assembly including a cam member and a second gear, a cam bridge follower in contact with the cam member, and a first plunger assembly having a first plunger and a first biasing element.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: July 19, 2022
    Assignee: Metronom Health, Inc.
    Inventors: Troy M. Bremer, Barry Lyons
  • Patent number: 11311679
    Abstract: The present invention relates to a handheld mechanical injection device by which set doses of a liquid medicament can be injected from a medical reservoir. The medicament is expelled through an injection needle by release of a power reservoir in the device, the power reservoir being fully or partially released by actuation of a user operable release member being positioned at or near an upper end of the injection device, the upper end being that end of the injection device which is opposite the injection needle.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: April 26, 2022
    Assignee: Novo Nordisk A/S
    Inventor: Tom Hede Markussen
  • Patent number: 11266441
    Abstract: A penetrator assembly for penetrating a bone and associated bone marrow is provided. The penetrator assembly may include a first connector having a first end and a second end; an outer penetrator extending from the second end of the first connector; the outer penetrator comprising a longitudinal passageway and a first tip; a second connector having a first end and a second end; and an inner penetrator extending from the second end of the second connector, the inner penetrator comprising a second tip. The first connector may be configured to engage the second connector, and the inner penetrator may be disposed in the longitudinal passageway of the outer penetrator when the first connector is engaged with the second connector.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: March 8, 2022
    Inventor: Larry J. Miller
  • Patent number: 11260202
    Abstract: Provided is an apparatus for injecting a lipolysis composition, the apparatus including a lipolysis composition storage, a pump, and at least one nozzle-type needle.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: March 1, 2022
    Inventor: Seung Min Yoo
  • Patent number: 11253645
    Abstract: The present invention teaches apparatuses, systems and methods for performing a variety of medical procedures, including those involving introducing one or more substances into a subject's body. In some embodiments, the invention teaches automatically performing guided injections into a tissue site (e.g. spinal cord) of a subject by using one or more electronically operated components including a cannula, a syringe pump, and a stereotactic device.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: February 22, 2022
    Assignee: Cedars-Sinai Medical Center
    Inventors: Pablo Avalos, Doniel Drazin, Clive Svendsen, Michael John Baker, Mark Sasha Drlik
  • Patent number: 11246993
    Abstract: According to the invention, a safety device for a pre-filled syringe with an injection needle comprises of a support body adapted to mount the pre-filled syringe, a needle shield slidably arranged with respect to the support body, a retention and locking means (M) for retaining and locking the needle shield with respect to the support body in a first and a second advanced position (PA1, PA2) and in a retracted position (PR). The needle shield comprises an annular flange adapted to rest on the skin of the patient receiving an injection. The retention and locking means (M) are arranged at a distal end of the safety device.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: February 15, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Gareth Roberts, John Slemmen, Matthew Ekman
  • Patent number: 11247033
    Abstract: A transdermal drug delivery apparatus includes a receptacle having a housing and a microneedle assembly mounted to the housing. The apparatus includes a reservoir for being mounted to the receptacle. The reservoir has an interior for containing fluid for being supplied to the microneedle assembly. The apparatus is adapted so that, when the apparatus is assembled, the reservoir is configured to move relative to the microneedle assembly along a path from an outer position to an inner position. The reservoir is closer to the microneedle assembly in the inner position than in the outer position. In the outer position, the reservoir is out of fluid communication with the microneedle assembly, and in the inner position, the reservoir is in fluid communication with the microneedle assembly. The apparatus also includes a plurality of connector parts spaced apart from one another along the path.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: February 15, 2022
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: Andrew T. Baker, Russell F. Ross, Elizabeth Deibler Gadsby, Luke Hagan
  • Patent number: 11234733
    Abstract: A cannula for use in a terminable intraosseous device comprises a cannula body, and a penetrator-independent proximal bone penetration indicator (PBPI) associated with the body for positively indicating initial penetration into the proximal bone. In various embodiments, the PBPI comprises a roughened surface provided at a distal end of the cannula body to assist in increasing an amplitude of vibrations that are generated immediately upon contact with a proximal bone cortex during performance of an intraosseous injection, a resilient element fixed at one end which becomes plastically deformed, a visually indicative element which is exposed when the distance between the cannula body and penetrator is changed, or a frictionally engageable element. In some embodiments, a stopper prevents additional penetration into the proximal bone, and a reinforcing member inserted within a cannula body lumen reinforces a thin-walled portion of the cannula body.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: February 1, 2022
    Assignee: WAISMED LTD.
    Inventors: Moshe Ben Mocha, Einat Swisa
  • Patent number: 11197789
    Abstract: Embodiments are disclosed of a method of controlling timing and/or dosage of a transdermal drug patch. For example, a control device operative to move the patch to one or more of a plurality of operational relationships with a skin of a patient, including being fully engaged with the skin, partially engaged with the skin, and disengaged with the skin. The device may include a roller that peels a patch on and off the skin. Optionally a convention patch is used. In some embodiments a patch and/or an adaptor has a mobile zone and an immobile zone. In some embodiments, an active surface of the patch fully contacts the skin in an engaged state. For example the patch may be attached to the device on a passive portion thereof.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: December 14, 2021
    Assignee: Alma Therapeutics Ltd.
    Inventors: Oz Cabiri, Yossi Gross, Ran Hezkiahu
  • Patent number: 11185688
    Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: November 30, 2021
    Assignee: Ichor Medical Systems, Inc.
    Inventors: Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox
  • Patent number: 11185641
    Abstract: Skin can be treated by piercing skin with a plurality of needles of an injection device and ejecting a dose of fluid therethrough. The device can include a housing, a plunger disposed in the housing, a cartridge disposed in the housing, and one or more dosing chambers. The plurality of needles can be coupled to the housing and be in fluid communication with the cartridge. Advancement of the plunger can cause a dose of fluid to be ejected from the plurality of needles.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: November 30, 2021
    Assignee: ALLERGAN, INC.
    Inventors: Ethan Franklin, Dimitrios Stroumpoulis, Zachary Dominguez, Justin Schwab, Bastien Mandaroux, Edwin Kayda
  • Patent number: 11147954
    Abstract: The present invention relates to applicators for administering microprojection arrays to skin and methods of administering microprojection arrays.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: October 19, 2021
    Inventors: Michael Carl Junger, Pierre Armand Vincent Lemaire
  • Patent number: 11147930
    Abstract: An apparatus for use with a syringe to provide a safety syringe, the apparatus including: a sheath deployable for at least partially covering a needle of the syringe; a sheath actuator for deploying the sheath; and a ratioed mechanism linking the sheath and the sheath actuator and configured such that a magnitude of movement of the sheath is greater than a magnitude of movement of the sheath actuator during deployment of the sheath.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: October 19, 2021
    Assignee: Owen Mumford Limited
    Inventors: Damian Alexander Holland, Clive Nicholls, Dale Marc Comley, Lee Thomas Smith, Joseph David Cowan
  • Patent number: 11123472
    Abstract: A system and method for a modular external interface for a skin penetrating appliance is provided. The modular device prevents internalization of bacteria, other infectious agents, or other unwanted materials from entering the access point for a catheter, Steinman pin, Kirschner wires, or other percutaneous instruments. The modular external interface provides for the hermaticity in the vicinity of the skin-appliance interface with fluid exudate or transudate egressing from the vicinity of the skin-appliance interface. The modular external interface forms a hermetic seal with the external neck of an implanted appliance with a locking feature that joins the main body of the modular external interface together around the neck of the appliance. The modular external interface provides mechanical stability to an implanted appliance so as to speed healing around a semi-permanent implanted appliance, as well as connection points for vacuum lines and drive lines for the insertion of medical devices.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: September 21, 2021
    Assignee: VIADERM, LLC
    Inventor: Susan Subilski
  • Patent number: 11103681
    Abstract: Needle assemblies are disclosed having a multi-purpose protective cap. The needle assemblies can embody a catheter assembly having a catheter hub and a catheter tube or a hypodermic needle mounted on a needle hub. The multi-purpose cap includes a first section covering the needle and a second section having a base portion for covering a hub, such as a needle hub or a catheter hub. The first section and the second section are separable from one another along a detachment line and the second section is re-useable as a securement device.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: August 31, 2021
    Assignee: B. Braun Melsungen AG
    Inventors: Aik Aun Tan, Wen Jenn Lim
  • Patent number: 11103210
    Abstract: An image guided autonomous needle insertion device including a delivery system, a path planner, an image processor, and a human machine interface. The system also includes an ultrasound probe in communication with a frame grabber, a percutaneous insertion device, and at least a first actuator for moving the percutaneous insertion device within a first degree of freedom and a second actuator for moving the percutaneous insertion device within a second degree of freedom. Each actuator has a corresponding position sensor for detecting its location with respect to a target. The system can further comprise an image processor for removing noise and segmenting the ultrasound images to highlight potential targets.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: August 31, 2021
    Assignees: Children's Hospital Medical Center, B.G. Negev Technologies and Applications Ltd.
    Inventors: Daniel Von Allmen, Hugo Guterman
  • Patent number: 11097067
    Abstract: An injection pen comprises a starting mechanism (1) and a driving mechanism (2). A needle pin (40) of the starting mechanism (1) fitted to a connecting rod (30) and a front spring (60) is disposed in a front housing (10) and an inner casing (20) therein. A front cover (50) is disposed at the front end of the front housing (10) and covers the needle pin (40). A rear housing (70) of the driving mechanism (2) and a driving casing (80) therein are connected to the front housing (10). A trigger tube (90) and a key panel (A0) are mounted in the driving casing (80). A push rod (A1) fitted to a rear spring (A2) is mounted in the trigger tube (90). An elastic baffle (83) of the driving casing (80) fastens the driving casing (80) and the push Rod (A1) and locks the rear spring (A2). An injection needle group (3) can be mounted between the starting mechanism (1) and the driving mechanism (2).
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: August 24, 2021
    Assignee: CC Biotechnology Corporation
    Inventor: Chin-Min Yeh
  • Patent number: 11045613
    Abstract: A detection device for recognizing the epidural space is provided. The detection device includes an upper case having a predetermined shape and a lower case coupled to the upper case to form a predetermined space part. A connection tube is provided at a predetermined position of the space part, one end of the connection tube communicates with a paracentesis needle part and the connection tube communicates with a pressure sensor for measuring pressure at a predetermined position of an outer peripheral part thereof. When the paracentesis needle part reaches the epidural space, the device allows a medicine injection catheter to be inserted into the connection tube thereby reaching the epidural space, with the connection tube and the paracentesis needle part connected to each other.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: June 29, 2021
    Assignee: SAEUM MEDITEC CO., LTD
    Inventor: Ye-Jung Lee
  • Patent number: 11000648
    Abstract: The present disclosure is generally directed to a resettable drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The drug delivery device comprises a housing, a cartridge holder, releasably attached to the distal end of the housing, a piston rod, engaging a housing insert and a drive member, a dose setting member, guided within the housing to allow rotation of the dose setting member during dose setting and dose dispensing, and a clutch for rotationally coupling the drive member and the dose setting member. The housing insert is rotationally constrained to the housing and is axially movable together with the drive member relative to the housing between a dose setting and dispensing position, and a resetting position. In the dose resetting position, the drive member is rotationally de-coupled from the housing.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: May 11, 2021
    Assignee: Sanofi
    Inventor: Paul Richard Draper
  • Patent number: 11000282
    Abstract: A punching device for punching a lumen and implanting an implant device includes at least the implant device for punching the lumen and for implantation into the lumen. In addition, the punching device includes an implantation device, a closure device, and an actuation device.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: May 11, 2021
    Assignee: KARDION GMBH
    Inventors: Armin Schuelke, Hardy Baumbach, Inga Schellenberg, Tobias Bergem