Abstract: The present invention discloses a medical injector and medicament loading system for use therewith. The medicament loading system includes cap for a medicament cartridge. The cap has a post for causing movement of the cartridge stopper toward the seal when the cap engages the medicament cartridge to thereby eliminate adhesion between the medicament chamber and the stopper. The medical injector according to the present invention includes the medicament loading system, i.e. a cartridge assembly, a needle free syringe assembly, and a power pack assembly.

Abstract: An injection apparatus includes components that facilitate injection of relatively viscous materials into a patient. An injection apparatus may include a transition-bore needle apparatus, which has a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, in which the diameter of the proximal end is greater than the diameter of the distal end. An injection apparatus may include a hand-held injection facilitation apparatus, which may be coupled to a syringe. The hand-held injection facilitation apparatus can include a pivot arm and a body with a rod disposed within the body and coupled to the pivot arm. Movement of the pivot arm results in a proximal or distal movement of the rod within the body to effectively cause material to be expelled from the syringe. An injection apparatus may include a transition-bore needle apparatus and a hand-held injection facilitation apparatus in combination.

Abstract: A medication injection or delivery system is provided for injecting fluids such as insulin within body tissue. The device includes a housing, a flexible shaft movably mounted within the housing, and a dose setting mechanism for controlling the movement of the shaft with respect to a fluid-containing cartridge removably positioned within or mounted to the housing. The flexible shaft, according to exemplary embodiments, includes a plunger and a flexible cable connected to the dose setting mechanism. The plunger and dose setting mechanism are connected together by the flexible shaft. The dose setting mechanism, in one aspect of the invention, includes a screw, a locking mechanism, and a nut assembly connected to the flexible shaft. The dose setting mechanism is used to set the dosage and prime the catheter. The plunger retracts into a recess to permit a new cartridge to be installed quickly.

Abstract: Disclosed is an infusion pump for expelling a fluid from a collapsible fluid reservoir to a patient. The pump includes a housing having a chamber therein for receiving the fluid reservoir. A first wall is provided on the housing for contacting the fluid reservoir, and a second wall is movable from a first position distanced from the first wall to form the chamber therebetween, and a second position relatively closer to the first wall. Advancing the movable wall from the first position to the second position expels fluid from the collapsible reservoir at a substantially constant rate by applying increasing force on the fluid reservoir through the dispensation cycle. Preferably, the first and second walls are provided with non-planar complementary surface configurations for contacting the collapsible reservoir. Retraction mechanisms for retracting the movable wall from the second position to the first position, and user readable indicium of the status of the dispensation cycle are also disclosed.

Abstract: A pump for dispensing a fluid from a reservoir provides a drive system seal within the pump. The pump includes a reservoir cavity adapted to receive the reservoir, and a drive system. The pump also includes at least one plunger slider having one end coupled to the drive system and the other end coupled to the reservoir. The plunger slider is adapted to translate from a retracted position to an extended position to dispense the fluid from the reservoir in response to actuation by the drive system. The pump further includes a sealing ring mounted around the plunger slider, and a spring disposed within the sealing ring. The sealing ring with the spring disposed therein is adapted to allow the plunger slider to translate from the retracted position to the extended position, and to prevent entry of fluid from the reservoir cavity into the drive system.

Abstract: The present invention is an improved needle-less injector device for the injection of fluids into the patients body. The injector device consists of a chassis, a nozzle on one end, a section for carpules containing the fluids to be injected, a piston, a spring-element acting on the piston, a compressing-mechanism for the spring-element and a release-mechanism. The compressing-mechanism can be connected to a coupling device of a standard dental driving unit.

Abstract: A hypodermic syringe with a selectively retractable needle includes an elongate barrel defining a receiver and a hollow bore. The syringe has a plunger with an elongate cavity open to the proximal end. The plunger is sized to fit within the bore of the barrel for a slidable movement to define a chamber for receiving and expelling fluids. The inside diameter of the cavity in the plunger is sufficient to accept telescopically at least a part of a first portion of the plunger. A second portion and the first portion are joined at an attachment to form a shoulder extending outwardly from the first portion, with the plunger being telescopically collapsible by movement of the second portion into the cavity by of sufficient distal force to frangibly disrupt the attachment. The syringe includes an elongate sleeve sized to fit over the first portion of the plunger and extend from the shoulder. The plunger includes a stopper to a form fluid tight seal with the barrel.

Abstract: A device for administering an injectable product in doses, wherein the device includes a casing, a reservoir for the product, a piston, an advancing element which moves the piston a selected path length, and a dosing mechanism including a number of dosing bodies and a dosing element operable to move the dosing bodies, wherein the path length is selected by the dosing element moving at least one dosing body between the piston and the advancing element.

Abstract: A drug solution delivery device comprises barrel (1) provided with a port at a distal end thereof and opened at a proximal end thereof, gasket (2) fluid-tightly and slidably arranged in the barrel, cylindrical connecting member (3) having proximal end (32) and distal end (31) to which gasket (2) is releasably connected, plunger (4) removably connected to proximal end (32) of connecting member (3), and pressed helical spring (5) arranged between gasket (2) and connecting member (3).

Abstract: Method and surgical instrument for treating prostate tissue including a surgical instrument having a main body, a needle deployment port, a needle, first and second handles and a lockout release mechanism to limit needle extension. Additionally, a kit includes the surgical instrument, together with a cystoscope, and optionally a syringe and reservoir of ethanol. The method includes needle-less injection and visualizing the ethanol injection by delivering both an echogenic agent and ethanol either by needle or needle-less injection or by providing an ultrasonically visible marker near the tip of the ethanol delivery cannula. The method also includes extending the needle transversely of the instrument housing using a link assembly.

Abstract: The invention relates to: A portable medication delivery device (1) comprising a medication cartridge (11) having an outlet (111) and a movable piston (112), and a housing (12) for holding said cartridge, and a flexible piston rod (13) being operable to engage and displace said piston along an axis (113) of said cartridge, and guiding means (14) for bending said piston rod away from said axis, and actuating means (15), and driving means (16, 17) for transferring movement from said actuating means to said piston rod, said driving means including a driving wheel (17) for displacing the piston rod (13), said flexible piston rod comprising regularly spaced first members (330; 331; 332) adapted to mechanically cooperate with corresponding second members (171) on said driving wheel. The object of the present invention is to provide a medication delivery system that combines compactness with an improved accuracy.

Abstract: It is a primary object of the present invention to provide an automated system based on an integral fluid bag for administering a variety of intravenous drug regimens and reducing the vagaries of existing manual systems. The fluid has multiple chambers configured to implement a prescribed intravenous medical therapy. Each chamber's geometry (size, shape), sequence and position, alone and in combination with the other chambers, matches the prescribed intravenous therapy or drug regimen. The bag's configuration assures that the intravenous therapy is administered in accordance with the prescribed drug regimen, thus automating the previous manual method. A choice of fluid bag configurations may be stocked so that a prescription for well known and widely accepted drug regimens may be filled by merely selecting a bag with the appropriate chamber configuration and filling it with the prescribed medications.

Abstract: An injection apparatus includes components that facilitate injection of relatively viscous materials into a patient. An injection apparatus may include a transition-bore needle apparatus, which has a proximal end, a distal end, and a lumen extending from the proximal end to the distal end, in which the diameter of the proximal end is greater than the diameter of the distal end. An injection apparatus may include a hand-held injection facilitation apparatus, which may be coupled to a syringe. The hand-held injection facilitation apparatus can include a pivot arm and a body with a rod disposed within the body and coupled to the pivot arm. Movement of the pivot arm results in a proximal or distal movement of the rod within the body to effectively cause material to be expelled from the syringe. An injection apparatus may include a transition-bore needle apparatus and a hand-held injection facilitation apparatus in combination.

Abstract: A needle-less hypodermic jet injection system includes a hand-held injector, and an energizing or cocking unit for use with the injector to prepare it for administering an injection. The hand-held unit includes a cartridge which provides a cylinder of liquid medication to be injected, an injection orifice, and an injection piston forceful movement of which causes an injection jet of medication to be expelled from the orifice. A power unit of the injector provides for forceful movement of the injection piston when a trigger is actuated. After being used to effect an injection, the injector is interfaced with an energizer unit which cocks the power unit preparatory to the next injection.

Abstract: A medication injection or delivery system is provided for injecting fluids such as insulin within body tissue. The device includes a housing, a flexible shaft movably mounted within the housing, and a dose setting mechanism for controlling the movement of the shaft with respect to a fluid-containing cartridge removably positioned within or mounted to the housing. The flexible shaft, according to exemplary embodiments, includes a plunger and a flexible cable connected to the dose setting mechanism. The plunger and dose setting mechanism are connected together by the flexible shaft. The dose setting mechanism, in one aspect of the invention, includes a screw, a locking mechanism, and a nut assembly connected to the flexible shaft. The dose setting mechanism is used to set the dosage and prime the catheter. The plunger retracts into a recess to permit a new cartridge to be installed quickly.

Abstract: A spring-actuated output drive device is used for example in medical aerosol therapy for a miniaturised high-pressure producing device for atomising a small dose of a liquid medicament. A locking-stressing-mechanism for such an output d rive device is to be stressed with the application of a relatively small amount of force and is to be released with one hand and is to operate reliably over a prolonged period of time. The locking-stressing-mechanism comprises a force step-up transmission, for example a screw thrust transmission for stressing the spring, an annularly arranged locking member with engaging locking surfaces, two abutments for limiting the travel of the spring and a release button. It is compact, economical to produce, easy to assemble and comprises components with a low rate of wear. It can be reliably and easily handled by unskilled persons, even when high spring forces are involved. A medicament to be atomised can thus be metered with a very high degree of accuracy.

Abstract: An injection device that is used with a syringe, wherein the injection needle of the syringe is initially introduced into the skin and the injection fluid is injected afterwards. The injection device is essentially driven and controlled by a control sleeve (6) which can be displaced and/or rotated in relation to the housing (7) and which can be moved between a closing and functional position (P1) and an open and safety position (P2). In the closing and functional position, the control sleeve prevents access to the syringe and activates a release device for the injection process. In the open and safety position, a syringe (1) can be removed or inserted.

Abstract: Disclosed is an infusion pump for expelling a fluid from a collapsible fluid reservoir to a patient. The pump includes a housing having a chamber therein for receiving the fluid reservoir. A first wall is provided on the housing for contacting the fluid reservoir, and a second wall is movable from a first position distanced from the first wall to form the chamber therebetween, and a second position relatively closer to the first wall. Advancing the movable wall from the first position to the second position expels fluid from the collapsible reservoir at a substantially constant rate by applying increasing force on the fluid reservoir through the dispensation cycle. Preferably, the first and second walls are provided with non-planar complementary surface configurations for contacting the collapsible reservoir. Retraction mechanisms for retracting the movable wall from the second position to the first position, and user readable indicium of the status of the dispensation cycle are also disclosed.

Abstract: The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all.

Abstract: The present invention relates to a metered, mechanically propelled, liquid dispenser. It has a main body cylinder having liquid and liquid advancing mechanism for advancing the liquid into a metered dosage dispensing chamber. There is a cocking mechanism which includes a lock pin, a stressed slot and a rest slot. When the cocking mechanism is locked, the advancing means is moved and liquid is ready for firing from the metered dosage dispensing chamber through a dispensing orifice. The cocking mechanism is slowly rotated while holding the main body cylinder vertically and the pin is manually moved into the rest slot thereby causing a plunger to be forced by a spring to push against a stop on a trigger which advances the trigger to rapidly force the liquid out of the metered dosage dispensing chamber through the dispensing orifice. The dispensing orifice includes a one-way valve which allows the liquid to be dispensed while preventing air from returning to the device.

Abstract: Disclosed is an infusion pump for expelling a fluid from a collapsible fluid reservoir to a patient. The pump includes a housing having a chamber therein for receiving the fluid reservoir. A first wall is provided on the housing for contacting the fluid reservoir, and a second wall is movable from a first position distanced from the first wall to form the chamber therebetween, and a second position relatively closer to the first wall. Advancing the movable wall from the first position to the second position expels fluid from the collapsible reservoir at a substantially constant rate by applying increasing force on the fluid reservoir through the dispensation cycle. Preferably, the first and second walls are provided with non-planar complementary surface configurations for contacting the collapsible reservoir. Retraction mechanisms for retracting the movable wall from the second position to the first position, and user readable indicium of the status of the dispensation cycle are also disclosed.

Abstract: A spring-powered infusion pump includes a syringe barrel 20 having two opposing openings 30, 55 forming two chambers 80, 90 between the first opening 30 and the plunger 40, and the second opening 55 and the plunger 40. The dispenser opening 30 has a one-way valve 35 to selectively release fluid retained within the first chamber 80. The second opening 55 is capped, and a spring 60 is compressed between the plunger 40 and syringe cap 50 within the second chamber 90. The spring 60 applies a force to the plunger 40 in the direction of the first opening 30. However, the one-way valve 35 retains the fluid within the first chamber 80, despite the force applied to the plunger 40, until a tubing set 70 equipped with an infuser connector 75 is attached to the dispenser opening 30 of the syringe barrel 20. The infuser connector 75 is insertable through the one-way valve 35 and thus provides a passageway for the fluid retained within the first chamber 80 of the syringe barrel 20.

Abstract: An injection device has a drive spring which, when released, urges a loaded capsule forwards to project its needle from the end of a barrel and ejects the dose. A light return spring then retracts the needle. The drive spring acts on the capsule plunger through a drive member having a movable barrier against which the rear end of the plunger initially abuts. A first trigger releases the drive member and drive spring and after an injection a second trigger can be actuated to shift the barrier relative to the drive member and allow the return spring to act.

Abstract: A reloadable auto-injector including a housing portion (1, 101) designed to receive a syringe (3), and a cover portion (2, 102), the auto-injector incorporating an injection device for automatically injecting the substance contained in the syringe, the injection device comprising: a piston (21) comprising a high portion (21b) and a low portion (21c), the low portion (21c) co-operating with the plunger of the syringe, the piston (21) being mounted to move, under the effect of an actuating spring (22) between a cocked position and an end-of-stroke position, the spring (22) being compressed in the cocked position; and trigger means (19) mounted to move between a blocking position in which they hold the piston (21) in its cocked position, and a releasing position in which they release the piston (21), the trigger means (19) being released from their blocking position by an actuating member; the auto-injector being characterized in that it further includes recocking means for recocking the automatic injection devi

Abstract: An injector is provided for automatic placement of a subcutaneous insertion set such as an infusion set or the like used for delivering a selected medication to a patient. The injector comprises a spring-loaded plunger having a head for receiving and supporting the insertion set in a position for placement of a medical insertion needle through the skin of a patient at a selected insertion site. The plunger head includes a safety lock mechanism for engaging and retaining the insertion set during spring-loaded advancement with a controlled force and speed toward the patient's skin to transcutaneously place the insertion needle. When the plunger head reaches a fully advanced position, with the insertion set placed on the patient, the insertion set is releasible from the safety lock mechanism with minimal force to permit quick and easy separation of the injector.

Abstract: A needleless injector for injecting medication through the skin of a patient includes a vial which holds a volume of liquid medication. The vial includes a vial piston which moves to force the liquid medication out of the vial. A power mechanism applies force to the vial piston. The power mechanism includes a power piston which has a plurality of ratchets. A spring is positioned to apply force to the power piston. A trigger engages the ratchets on the power piston to hold the power piston in place against the force applied by the spring. The trigger selectively releases the power piston so that the power piston moves in response to the force applied by the spring. The power piston applies the force to the vial piston to cause the vial piston to force the liquid medication out of the vial. A cocking mechanism applies force to the power piston to move the power piston against the force of the spring to engage the ratchets.

Abstract: A multi-dose infusion pump employs a piston sliding within the internal chamber of a pump housing to dispense liquid from a port. The peripheral surface of the piston has a sequence of steps in a radial pattern spaced at intervals along the longitudinal axis of the chamber. A cap is rotatably mounted to the pump housing and includes a stop that limits forward movement of the piston by engaging a selected one of the steps on the piston at each rotational position of the cap. This causes a series of predetermined quantities of liquid to be dispensed as the cap is rotated to align the stop with each step in sequence. A spring between the cap and piston urges the piston forward in the chamber to dispense liquid from the port.

Abstract: An injection device has a two part barrel. The forward part (10) telescopes into the rear part (3) and within the barrel a capsule (1) with a needle (2) at its forward end is initially held by a trigger (11) formed integrally with the forward part (10) so that the needle (2) does not project. The trigger (11) is inoperable at this stage, being inaccessible because of the telescopic overlap. A spring (20) acts on a plunger at the rear of the capsule. When the overlap is increased, the trigger (11) becomes accessible through a slot (7), and when it is operated the capsule (1) is released for the spring (20) to shoot it forwards and eject the dose through the now projecting needle (2). The capsule (1) may have a two part dose and its mixing may then be effected by the spring (20), fully compressed after the overlap increase, urging the plunger forwards.

Abstract: The invention is directed to a device (V) for the output of a liquid (2) in partitioned amounts (2') from a store room (3), preferably in form of a cartridge (K), over an output mouth piece (4), preferably in form of an injection needle (5), and has the object the application of exactly reproducible amounts from a reserve amount and its safe application. This is obtained by an intermediate reservoir (17) taking up the partitioned amount (2') from the store room (3), whereby for the intermediate reservoir (17) an output piston (19) is provided with a penetration canal (18) to fill the intermediate reservoir (17).

Abstract: Device for the dosed release of an injectable product, comprising a housing, a retainer for a container, containing the product, in which a piston is displaceably accommodated, whose displacement in a feed direction causes the release of a product dose, a driven member including a driven rod which protruding into the container when the container is accommodated in the housing pushes the piston in the feed direction to release the product, at least one drive member engaging with the driven member, the driven member being displaced in the feed direction by the activation of the drive member, wherein the driven member contains a driven bush surrounding the driven rod, which driven bush engages into the drive member and is displaced together with the driven rod, and a rear wall--in relation to the feed direction--of the container protrudes at least during a release into an annulus formed between the driven rod and the driven bush.

Abstract: A pen shaped syringe with automatic needle insertion has an injection system integrally displaceable in a housing and comprising a basic part carrying a medicine reservoir with a hypodermic needle at its distal end, and a dosing mechanism with a carrier engaging a cogged piston rod, the carrier being coupled to a dose spindle in a rotatable but not displaceable way. The dose spindle is provided with a thread engaging a thread in a sequence part having protrusions engaging slots in the basic part to allow a limited axial movement of the parts in relation to each other, the extent of the movement being defined by the rotational position of the dose spindle. A spring is compressed between the basic part and the housing when the basic part is moved in the proximal direction by exerting a cocking force on the sequence part which part after having performed the set limited axial movement in relation to the basic part carries this basic part against the force of the spring.

Abstract: An applicator (10) to deliver a liquid via a needle (20). The applicator (10) includes a shroud (44) which cooperates with a trigger (41) and trigger lock (52) so that the needle (20) is only exposed upon actuation of the trigger (41) and liquid is only injected when the shroud (44) is retracted to a position at which a desired length of the needle (20) has penetrated.

Abstract: A jet injector, and a method, for injecting fluid medicament into a patient in a two-stage process. During the first stage fluid is expelled from the injector under relatively high pressure, to create a hole through the skin of the patient. During the second stage, fluid is infused through the hole into the patient at a much lower pressure, and for a much longer period of time. The jet injector includes a syringe unit, and a drive mechanism which is selectively connectable with the syringe unit. Specifically, the drive mechanism includes two springs which are positioned to urge against a push rod as they elongate. When the drive mechanism is engaged with the syringe unit, the push rod is positioned longitudinally co-linear with a plunger in the chamber. When the springs are released, they push the push rod which, in turn, pushes the plunger, causing the fluid to be expelled through an injection tube connected to the chamber.

Abstract: Needleless jet-injection device, characterized in that it consists of a body (1) having at one of its ends (4, 5) a cap (3), which, thanks to a relative movement between these elements, may drive a loading mechanism (2), co-operating with an impact component (17) which has to strike the piston of a cartridge (28) which is made of a material that does not pollute the environment and which contains the active product to be injected, this cartridge (28) being moreover placed at the other end of the said magazine-less body (1) and in the axis of said impact component (17), for single use.

Abstract: A liquid drug delivery device is adapted to be adhered to the skin of a subject by a base member defining a skin-contacting surface having an adhesive coating. A columnar cartridge serves as reservoir for the drug and is incorporated in a housing which is connected to the base member such that in use the longitudinal axis of the cartridge is disposed substantially parallel to the skin-contacting surface. A delivery needle communicating in use with the interior of the cartridge penetrates the skin of the subject when the housing snaps downward relative to the base member. This action also causes the actuation of a citric acid/sodium bicarbonate gas generator which generates a gas to move a piston within the cartridge, compressing the drug compartment. This compression causes a stopper to be penetrated by a conduit in communication with the delivery needle, allowing the drug to be ejected from the compartment through the needle and into the subcutaneous tissue of the subject.

Abstract: An injector is provided for automatic placement of a subcutaneous infusion set or the like used for delivering a selected medication to a patient. The injector comprises a spring-loaded plunger having a head for receiving and supporting an infusion set in a position for placement of an insertion needle and related cannula through the skin of a patient at a selected insertion site. The plunger head includes a safety lock mechanism for engaging and retaining the infusion set during spring-loaded advancement with a controlled force and speed toward the patient's skin to transcutaneously place the insertion needle and cannula. When the plunger head reaches a fully advanced position, with the infusion set placed on the patient, the infusion set is releasible from the safety lock mechanism with minimal force to permit quick and easy separation of the injector.

Abstract: A nozzle assembly adapted for an injector, includes a guide for proper application of injections. The guide has first and second wings each extending outwardly and away from the chamber at an angle. These wings are preferably symmetrical and form a V-shape to accommodate appendages such as fingers, toes, or penises. The wings may be curved or straight depending upon the curvature of the substrate to be injected. Also, depending upon the angle layout or length of the wings relative to the chamber and the symmetry of the wings, injections can be set to penetrate at almost any desired angle.

Abstract: A syringe actuation device includes a housing containing a spring-biased piston that applies an actuation force to a syringe plunger inserted into the housing. A pivoting mechanism causes the piston to pivot with respect to the longitudinal axis of the housing as the piston moves along that axis to actuate the plunger, whereby the axially-directed component of the force applied by the piston to the plunger remains substantially constant throughout the stroke of the piston. In one embodiment, the device comprises an internally-threaded outer sleeve having a longitudinal opening for receiving a pre-filled syringe with an extended plunger and a distal opening through which the syringe barrel extends, and an externally-threaded cylinder, containing the piston, that threads into the proximal end of the sleeve so as to bring the piston to bear against the plunger. The pivoting mechanism comprises a tapered internal diameter of the cylinder, and a sloped spring seat on the piston.

Abstract: The injector has a reservoir containing a drug. The injector has a tubular body with a tubular wall, a plunger, a needle and a plunger rod. The tubular body also has two springs. The first spring is compressed from bearing on a part of the inner surface of the tubular body and on a piece that is connected to the plunger rod. The first spring pushes in the direction in which the needle protrudes. The second spring acts in the opposite direction of the first spring. The second spring is compressed by bearing on a part of the inner surface of the injector body and on a ring. The force exerted by the second spring is greater than that exerted by the first spring. The ring is slidably mounted and is capable of entraining the reservoir in the direction of the retraction of the needle. The ring is blocked by a movable abutment. The plunger rod cooperates with the movable abutment to release the second spring and cause the retraction of the needle.

Abstract: An automatic injector comprises a housing, a tubular cartridge disposed in the housing, the cartridge having a rearward portion thereof with a predetermined inner diameter and an inwardly extending shoulder connecting a forward portion of the cartridge with a smaller inner diameter than the predetermined diameter. A charge of liquid medicament is normally disposed in the cartridge, and a needle is disposed within the housing and adapted to communicate with the medicament through a forward end of the cartridge to dispense the medicament therethrough. A plunger disposed within the cartridge and rearwardly confines the medicament and has a rearward portion with a diameter sized to form a seal with the predetermined inner diameter of the rearward portion of the cartridge. The plunger is movable forwardly through the cartridge in slidingly sealed relation with respect thereto to displace the medicament through the needle.

Abstract: An assembly for automatically injecting a fluid into the body is provided. The assembly includes a drive assembly, which can be reused many times, and a disposable assembly including a sleeve which contains a syringe. The drive assembly includes a housing having an open end to which a collar is mounted. The collar includes a radially inwardly extending pawl. The sleeve includes a generally cylindrical body having a radially outwardly extending rib. The rib defines a notch which is engageable with the pawl when the disposable assembly is inserted within the drive assembly housing. Engagement of the pawl within the notch prevents the disposable assembly from being ejected from the drive assembly housing should the actuating button of the drive assembly be pushed prematurely. Ejection of the disposable assembly requires its rotation with respect to the drive assembly housing to first disengage the pawl from the notch.

Abstract: An automatic medicament injector employing a non-coring needle having side port geometry optimized to minimize or eliminate the coring of a rubber seal or septum when impaled by the internal needle tip of the cannula. The geometry avoids direct exposure of the butt end face of the needle to the rubber seal by providing a crimp to the material at the butt end and openings in the side thereof using electro-discharge machining (EDM) processes providing plural openings therein for introduction of medicament or aspiration through the side port geometry. The automatic medicament injector structure facilitates administration of a medicament to a predetermined target tissue avoiding exposure of the medicament or drug to tissues which would undesirably be damaged by such exposure.

Abstract: A modular fluid medication injection assembly (10) includes a medicant module (12) and an activator module (14). The medicant module (12) holds a replaceable, disposable syringe subassembly (24). The activator module (14) contains a driver (56) and driver release (70) for deployment and injection of the syringe subassembly. The modular design permits the use of various-sized medicant modules (12) to accommodate different sized syringe subassemblies (24) and dosages of fluid medication. Additionally, spare modules (12) may be kept on hand for administering multiple dosages from the same syringe subassembly. A carrying case (166) for the injection assembly (10) is also disclosed.

Abstract: An injection device is provided for a continuously variable metering and administering of a liquid preparation and having a holder device for a multi-dose injection cartridge, the rear piston of which may be moved forward by means of a piston rod. The piston rod is provided with releasable locking means having at least one longitudinal groove having a wedge-shaped cross section and at least one locking lug having a cross section adapted to that of the groove, and means for urging the locking lug into said grooves to lock the movement of the piston rod, or to release the locking lug from said groove to free the movement of said piston rod. At its rear end, the piston rod is connected to a spring device for moving the piston rod forward and to a device for determining the stroke of the piston rod when the preparation is administered.

Abstract: A reloadable automatic or manually usable medicine injection apparatus having a barrel which receives a syringe subassembly. The syringe subassembiy includes an ampule for housing fluid medication, a needle, a plunger stopper, and plunger shaft which allow removal and manual use. The injection apparatus includes a driver for forcing the syringe subassembly to inject the needle and displace fluid medication. The injection apparatus preferably includes a trigger handle, sheath remover, and removable stop system for delivery of multiple doses.

Abstract: An injection device is adapted to eject a sequence of doses from the needle of a capsule carried within its barrel-like body. A plunger extending rearwardly from the capsule has ratchet teeth along its length engaged by pawls at the forward end of a drive tube biased forwardly by a spring. The capsule is in a sleeve-like carrier having limited longitudinal travel, a lost motion connection to the drive tube and an engagement with the ratchet teeth by pawls. The drive tube can be releasibly retained in a rearward position by a trigger mechanism. When released, the drive tube urges the plunger, capsule and carrier forwards to project the needle. The liquid acts effectively as a solid. With the carrier stopped, the plunger carries on to eject a dose, clicking past the carrier pawls. The re-prime, the knob is pulled to retract the drive tube and the carrier, the lost motion connection allowing the drive tube to move further and have its pawls click back along the plunger until the trigger mechanism re-engages.

Abstract: A syringe is provided for injecting multiple sequential dosages of a liquid medicine includes a single actuator for initiating a penetration and injection sequence. The syringe hereof is adjustable for different dosages while providing for physical selection of a desired, predetermined dosage. The syringe includes a retraction mechanism for withdrawing the needle into a protective collar after administration of the dosage. The syringe receives a vial for administering multiple dosages without the necessity of replacing the vial after each administration.

Abstract: A medication infusion pump is provided for controlled delivery of medication to a patient, wherein the pump includes a space-efficient flexible drive plunger for advancing a piston within a medication-containing syringe or cartridge for administration of the medication to a patient. The infusion pump comprises a compact housing defining a syringe chamber for receiving and supporting the barrel of a medication-containing syringe or cartridge having a nose end adapted for luer connection to catheter tubing through which the medication is delivered to the patient. An open rear end of the syringe barrel carries a piston which can be advanced in a controlled manner to dispense the medication. In the preferred form, the flexible drive plunger comprises a spring tape with a free end adapted for removable connection to the piston.

Abstract: An injector system utilizes a disposal ampule or, in one instance, a disposal syringe, in all cases being characterized by "tracked" injection wherein the medicament within the ampule or syringe is dispensed as a linear function of needle penetration, and the complete injection operation is executed such that the needle is never exposed. The needle is withdrawn within the medicament chamber after use where it cannot injure anyone except in one instance, in which the needle is capped after the plunger spindle is snapped to prevent reuse of the syringe. The objectives of the improvements are comfort to the patient, ease of use by the administrator and safety for all involved.

Abstract: An automatic injector is provided having at least two chambers containing different ingredients of a medicament separated by .?.an impermeable membrane. A lance is movable independently of a plunger to cut or pierce the membrane before a spring-loaded drive member for the plunger is released to drive a needle out of the body of the injector and discharge the medicament through the needle. A removable safety clip is provided for preventing movement of art actuating cap into an operative position for advancing the lance, and release of the drive member is preventable by a removable safety pin until the injector is to be used..!. .Iadd.a sealing structure. One of the chambers has a needle disposed therein. The sealing structure is conditionable to permit the ingredients to mix in the injector in response to a predetermined actuating procedure before the ingredients are injected.