Treating Material Forced Into Or Out Of Body By Self-acting Fluid Pressure, Motor-driven, Or Mechanical Energy Storing Means (e.g., Pressure Infusion Or Aspiration, Etc.) Patents (Class 604/131)
  • Patent number: 11400214
    Abstract: Methods and systems may quantify how much contrast fluid is injected into a patient by a powered fluid injector. A controller of the powered fluid injector can receive a command from a user to begin dispensing contrast fluid. The controller may determine whether a hemodynamic pressure signal is present from a pressure sensor in fluidic connection with the vasculature of the patient. The powered fluid injector may dispense a quantity of contrast fluid in response to the command. The controller may add the quantity of contrast fluid to an injection quantity if the hemodynamic pressure signal is present just prior to and/or just after the quantity of contrast fluid is dispensed. The controller may refrain from adding the quantity of contrast fluid to the injection quantity if the hemodynamic pressure signal is not present just prior to and/or just after the quantity of contrast fluid is dispensed.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: August 2, 2022
    Assignee: ACIST MEDICAL SYSTEMS, INC.
    Inventor: Blaise D. Porter
  • Patent number: 11400237
    Abstract: Provided is a medicine infusion apparatus capable of infusing a liquid medicine into a human body by using a medicine container configured to discharge the liquid medicine contained therein, along a designated path when a pressure is applied from outside, the medicine infusion apparatus including one or more medicine pressing units including one or more inflatable parts capable of being inflated by air to apply a pressure to the medicine container, a first pumping unit capable of inflating one of the inflatable parts by including a first pump capable of generating air of a preset pressure, and a first pipe connectable to the one of the inflatable parts, and a heating unit including a thermoelectric module capable of heating the medicine within a preset temperature range. According to the present invention, the medicine infusion apparatus may be produced as a compact portable apparatus by using a low-capacity battery and be used for emergencies at accident sites where electricity may not be easily supplied.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: August 2, 2022
    Assignee: IMPACT KOREA CO., LTD.
    Inventor: Moung Sook Lee
  • Patent number: 11389585
    Abstract: A pressure jacket configured for connecting to an injector head of a fluid injector has an open distal end, an open proximal end, and a sidewall defining a throughbore extending between the distal end and the proximal end along a longitudinal axis. The throughbore is configured for receiving at least a portion of a syringe. The pressure jacket has at least one syringe retaining element positioned at least partially within the throughbore. The at least one syringe retaining element is configured for engaging at least a portion of the syringe during pressurized delivery of fluid from the syringe to prevent or limit a distal movement of the syringe relative to the pressure jacket.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: July 19, 2022
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Michael Spohn, Kevin Cowan, Barry Tucker, Michael McDermott
  • Patent number: 11389584
    Abstract: Priming systems and infusion assemblies are provided. For example, a priming system comprises a priming conduit having a priming portion and a pressure portion. The priming portion is in fluid communication with a first fluid source, with an inlet and an outlet for ingress and egress of a first fluid from the first fluid source. The pressure portion is in fluid communication with a second fluid source connected by a connector. Disposed within the priming conduit are a biasing member and a valve having an open position and a closed position. The biasing member is in operable communication with the valve to urge the valve into the closed position such that the valve defaults to the closed position. The open position allows the first fluid to flow from the inlet to the outlet and the closed position prevents the first fluid from flowing from the inlet to the outlet.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: July 19, 2022
    Assignee: Avent, Inc.
    Inventor: Hector Dung Truong
  • Patent number: 11383029
    Abstract: An injector system for injecting fluid includes a syringe and an injector. The syringe includes a body and a plunger movably disposed within the body. The plunger has at least one flexible leg extending toward the rearward end of the body. The injector has a housing with a front plate, a drive member at least partially disposed within the housing and operable to engage the plunger, and a syringe release assembly operable to release the syringe. The syringe assembly includes a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing and a plunger release tube surrounding at least a portion of the drive member. The plunger release tube has a first end rotationally engaged with the syringe release gear. Rotation of the syringe release assembly releases the at least one flexible leg from the drive member.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: July 12, 2022
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Charles Lang, Christopher Swenglish, Luis Castillo, Stephen Schulte
  • Patent number: 11376363
    Abstract: A medicament delivery device includes a generally elongated tubular housing having opposite proximal and distal parts; a needle shield sleeve slidably and coaxially arranged inside the housing with a proximal part of the sleeve protruding a distance outside the proximal part of the housing; a syringe carrier mechanism having a syringe carrier slidably and coaxially arranged within the needle shield sleeve, a syringe having a stopper, a medicament, and a needle, the syringe being coaxially arranged within the syringe carrier; and a holding member connected to the syringe carrier; a first activator member an a second activator member; a drive mechanism adapted to accumulate a drive force for moving the syringe carrier mechanism in a first step and a second step. The second activator member is arranged within an information device for producing audible, visual, and/or tactile feedback to a user about a completed injection.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: July 5, 2022
    Assignee: SHL MEDICAL AG
    Inventor: Oscar Alexandersson
  • Patent number: 11369769
    Abstract: An anesthetic administration device comprising an infusion device, which is in fluid connection with a regional anesthetic needle by means of a feed tube. The infusion device comprises one or more anesthetic flow devices capable of triggering forward flow, and optionally backward flow, of the local anesthetic through the regional anesthetic needle. Forward, and optionally backward flow, of the local anesthetic through the regional anesthetic needle is controlled by a controller that comprises one or more actuator switches. The one or more actuator switches are positioned on the device 1 such that they may be operated by hand.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: June 28, 2022
    Assignee: The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust
    Inventors: Peter Jeffrey Young, Joseph Joachim Carter, Emad Eldin Fahmy Fawzy, John Edward Gibson
  • Patent number: 11369747
    Abstract: A syringe has a syringe body configured to receive a product for injection. Gripping wings are arranged at one end of the syringe body. A piston rod is mounted so as to be able to slide inside the syringe body. A stop is arranged at a first end of the piston rod and has an end-of-travel position inside the syringe body. A pusher is arranged at a second end of the piston rod. The pusher has a mass greater than or equal to a threshold value beyond which the syringe has a center of gravity situated outside the syringe body when the stop is in the end-of-travel position.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: June 28, 2022
    Assignee: Laboratoires Vivacy
    Inventors: Ludovic Heim, Denis Gantin
  • Patent number: 11331423
    Abstract: An injection system includes an injector head that is configured to control delivery of a designated fluid to a patient. The injector head includes a syringe interface along an active side of the injector head. The syringe interface has a receiving cavity that is configured to receive a syringe barrel. The injector head also includes an internal sensor. A magnetic switch has an external magnet outside of the injector head. The external magnet is operable to modify a magnetic field experienced by the internal sensor to activate the internal sensor.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: May 17, 2022
    Assignee: Illinois Tool Works Inc.
    Inventors: Raymond Jozwik, J. Michael Cude
  • Patent number: 11305052
    Abstract: A suction-based medical dressing assembly and method of dermal irrigation provides a flexible tube that is fluidly coupled to at least two bifurcated tube portions defined by a plurality of apertures. The tube has a proximal end opening for discharging ambient fluid. The length of the bifurcated tube portions is surrounded by an absorbent gauze material covered substantially with an occlusive sheet material, and having an adhesive strip thereon. A vacuum assembly creates a negative pressure in the tubes. The ambient fluid is absorbed by the absorbent material, and the negative pressure sucks the fluid through the apertures in the bifurcated tube portions for discharge through the opening in the tube. In operation, a patient applies the adhesive side of the occlusive device to the skin where liquid removal is desired and activates the vacuum-inducing source, thereby causing fluid runoff from the patient to be effectively removed for disposal.
    Type: Grant
    Filed: April 7, 2019
    Date of Patent: April 19, 2022
    Inventor: Steven Simpson
  • Patent number: 11278666
    Abstract: A medication infusion device includes a medication container containing liquid medication; an infusion needle; and a reciprocating pump having a pump chamber. The liquid medication is withdrawn from the medication container into the pump chamber during suction operation of the reciprocating pump, and the liquid medication is dispensed out of the pump chamber through the infusion needle during dispensing operation of the reciprocating pump. There are also mechanisms preventing liquid from flowing through the infusion needle during suction operation of the reciprocating pump and preventing liquid from flowing back into the medication container during dispensing operation of the reciprocating pump. The medication infusion device may further include a microcontroller to control medication infusion volume and rate.
    Type: Grant
    Filed: November 17, 2019
    Date of Patent: March 22, 2022
    Inventor: Min Wei
  • Patent number: 11273053
    Abstract: Systems and methods for delivering bone graft material, which utilize a graft material cartridge. The bone graft delivery system comprises an outer delivery unit and a graft material cartridge. The bone graft delivery system is configured to provide a mechanism that loads graft material through a delivery tube and not at the end or outside of it.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: March 15, 2022
    Assignee: INTEGRITY IMPLANTS INC.
    Inventors: Wyatt Drake Geist, Jared M. White
  • Patent number: 11273252
    Abstract: An injection system includes an injector head that is configured to control delivery of a designated fluid to a patient. The injector head includes a syringe interface along an active side of the injector head. The syringe interface has a receiving cavity that is configured to receive a syringe barrel. A side cover has a syringe opening therethrough. The side cover is sized and shaped to cover at least a portion of the active side of the injector head such that the receiving cavity and the syringe opening align with each other to form a port that receives the syringe barrel.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: March 15, 2022
    Assignee: Illinois Tool Works Inc.
    Inventors: Robert Schaser, Raymond Jozwik, Michael Leonhard
  • Patent number: 11257580
    Abstract: An apparatus comprising a controller. The controller includes an input/output (I/O) module and a rule module. The I/O module is configured to present a question for a patient when communicatively coupled to a user interface and receive patient information in response to the question via the user interface. The rule module is configured to apply a rule to the patient information and generate a suggested insulin pump setting from application of the rule. Other devices, systems, and methods are disclosed.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: February 22, 2022
    Assignee: Tandem Diabetes Care, Inc.
    Inventor: Michael L. Blomquist
  • Patent number: 11253653
    Abstract: A segmented piston rod for an injection device includes multiple segments joined together via a hinge located on one side of each segment. The piston rod can be bent in one direction by articulating subsequent hinges while an axial force can be transmitted by the segmented piston rod to the stopper when the subsequent hinges are closed and the segments abut each other opposite to the one side of the hinge. The segmented piston rod is secured against rotation relative to the housing around the longitudinal axis of the segmented piston rod. The segmented piston rod has a last element which abuts the stopper in the reservoir and a first segment which is opposite to the last segment. The first segment is includes an internal thread matching an external thread of a drive sleeve and rotation of the drive sleeve advances the piston rod towards the stopper of the reservoir.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: February 22, 2022
    Assignee: Ypsomed AG
    Inventors: Patrick Hostettler, Jürg Hirschel, Simon Scheurer
  • Patent number: 11241546
    Abstract: The present disclosure relates to a holder for a recording unit, which recording unit is arranged with an interface configured to cooperate with an interface of a medicament delivery device for obtaining information regarding the use of the medicament delivery device, the holder has an interface configured to cooperate with the interface of the recording unit, and the holder further has attachment elements for attaching the holder to a suitable surface.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: February 8, 2022
    Assignee: SHL MEDICAL AG
    Inventors: Daniel Carlsson, Rasmus Renstad, Christina Mansjö
  • Patent number: 11229740
    Abstract: A wearable drug delivery device that can deliver high volumes of liquid drugs stored in one or more corresponding containers to a patient is provided. The wearable drug delivery device can include first and second containers to store first and second liquid drugs, respectively. A first set of energy transfer spheres can be coupled to a first spring and a first plunger positioned within the first container. A second set of energy transfer spheres can be coupled to a second spring and a second plunger positioned within the second container. The first spring can expand to advance the first set of energy transfer spheres and the first plunger to expel the first liquid drug for delivery to the patient. The second spring can expand to advance the second set of energy transfer spheres and the second plunger to expel the second liquid drug for delivery to the patient.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: January 25, 2022
    Assignee: INSULET CORPORATION
    Inventor: David Nazzaro
  • Patent number: 11219712
    Abstract: A wound fluid collection system includes a canister with a chamber fluidly connected to a wound dressing in a tissue site through an inlet and also fluidly connected to a reduced pressure source through an outlet. At least a portion of the canister is collapsible and yet can be maintained in an extended state when exposed to subatmospheric pressure. The canister is releasably attachable to a supporting member.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: January 11, 2022
    Assignee: KCI Licensing, Inc.
    Inventors: Christopher Brian Locke, Aidan Marcus Tout
  • Patent number: 11221368
    Abstract: Systems and methods for determining battery capacity in portable electronic devices are disclosed. In one embodiment, a method for determining battery capacity in a portable electronic device may include: (1) disabling battery charging for the portable electronic device; (2) measuring a voltage and a current across terminals for a battery installed in the portable electronic device; (3) calculating a voltage offset across the battery using an estimate of an internal resistance for the battery by multiplying the current by the estimate of the internal resistance for the battery; (4) calculating an estimate of the open circuit voltage for the battery by subtracting the voltage offset across the battery calculated from the measured voltage; (5) retrieving a battery capacity based on the estimate of the open circuit voltage; (6) quantifying the battery capacity; and (7) displaying the quantified battery capacity.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: January 11, 2022
    Assignee: VERIFONE, INC.
    Inventors: Robert Stuckey, Nageswari Srinivasan
  • Patent number: 11213620
    Abstract: Methods, devices, and components are provided to reduce tissue resistive pressure during a subcutaneous drug delivery operation by increasing the size of the injection cavity by partially retracting the drug delivery member after inserting the drug delivery member to a subcutaneous position. The drug delivery devices described herein include a magnetic actuator operably coupled to a primary container assembly including a drug delivery member. Power can be selectively provided to the magnetic actuator by a controller to retract the drug delivery member a predetermined distance to relieve pressure in an injection cavity in a patient. A force sensor can provide the controller with a drug delivery member insertion force. The controller can then estimate a tissue resistive pressure based on the drug delivery member insertion force and determine the predetermined distance for the drug delivery member retraction based on the tissue resistive pressure.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: January 4, 2022
    Assignee: AMGEN INC.
    Inventors: Ali Nekouzadeh, Carl Conrath, Scott Robert Gibson, Basel Hasan Taha
  • Patent number: 11207384
    Abstract: The invention is a composition of insulin or insulin analog that has faster pharmacokinetic action than commercial formulations of rapid-onset insulin analog products.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: December 28, 2021
    Assignee: Eli Lilly and Company
    Inventors: Jun Zhang, Chad Donald Paavola
  • Patent number: 11191946
    Abstract: Systems and methods for generating blood flow with a pump incorporating linear bearing technology are provided. The pump may include an actuator assembly, a moving assembly, and a linear hydrodynamic or thin-film bearing positioned within a housing. The moving assembly may include at least one magnet and the actuator assembly may include a magnetic assembly for selectively generating a magnetic field to cause linear reciprocating movement of the moving assembly with respect to the actuator assembly. The linear hydrodynamic or thin-film bearing may include a bearing portion on the moving assembly that is in fluid communication with a bearing portion on the actuator assembly or pump housing. The system may involve an implantable pump, an extracorporeal battery and a controller coupled to the implantable pump. The implantable pump may be suitable for use as a left ventricular assist device (LVAD).
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: December 7, 2021
    Assignee: CorWave SA
    Inventors: Trevor Snyder, Carl N. Botterbusch, Petrus Le Blanc, Bastien Wittig
  • Patent number: 11191677
    Abstract: A tampon insertion device for inserting a tampon from a tampon applicator into a vaginal canal. The devices includes a hollow casing having an open distal end, a proximal end, a top wall extending between the proximal and distal ends, an open bottom opposing the top wall, and a clamp portion located at the distal end of the casing. The device further includes a plunger actuator located in the interior of the casing for linear movement therein, and a handle slidably positioned external to the casing and connected to the actuator such that linear sliding movement of the handle with respect to the casing causes a corresponding linear movement of the actuator within the casing. A method of inserting a tampon is also provided.
    Type: Grant
    Filed: May 18, 2019
    Date of Patent: December 7, 2021
    Assignee: TINA HOLDINGS, LLC
    Inventors: Alison Marie Kight, Lovic Port Ryals, Sarah Bush
  • Patent number: 11173251
    Abstract: Fluid injection devices and related systems and operating methods are provided. An exemplary injection device includes an actuation arrangement to facilitate delivering fluid from a container, a user interface element coupled to the actuation arrangement, a data storage element to maintain one or more patient-specific parameter values and historical bolus data, and a control module coupled to the actuation arrangement and the data storage element. The control module of the injection device determines a bolus amount of the fluid to be delivered based at least in part on the one or more patient-specific parameter values and the historical bolus data in response to receiving a user input indicative of a desire to administer a bolus, and the control module configures the actuation arrangement to automatically deliver the bolus amount in response to manual actuation of the user interface element.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: November 16, 2021
    Assignee: Medtronic MiniMed, Inc.
    Inventor: Anirban Roy
  • Patent number: 11173256
    Abstract: An injection device is used for “tattooing” markers inside the heart of a patient at specific locations. Placement within the heart of markers, such as points marked with a radiopaque dye, may reduce the use of x-ray dye and echocardiography, may allow a quicker cardiac procedure, and thus may improve the procedure outcome for the patient. Alternatively or additionally to cardiac marking with a radiopaque dye, cardiac tissue fibrosis, cardiac tissue contraction, and/or cardiac tissue stiffening (or hardening) can be promoted at specific locations by delivering a suitable substance.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: November 16, 2021
    Inventors: Michael B. McDonald, Shalaka V. Bapat
  • Patent number: 11167124
    Abstract: The catheter device comprises a motor at the proximal end of the catheter device and a drive shaft, extending from the proximal end section to the distal end section of the catheter device, for driving a rotating element located at the distal end of the catheter device. The catheter device also comprises a hose-like catheter body which encompasses the drive shaft and extends from the proximal end section to the distal end section. At the proximal end of the catheter device, the drive shaft is connected to a motor by a clutch. The clutch is a magnetic clutch with a proximal and a distal magnet unit. The proximal magnet unit is connected to the motor and the distal magnet unit to the drive shaft. The distal magnet unit is mounted fluid-tight in a clutch housing. The proximal end of the catheter body makes a fluid-tight connection with the clutch housing.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: November 9, 2021
    Assignee: AIS GMBH AACHEN INNOVATIVE SOLUTIONS
    Inventors: Joachim Georg Pfeffer, Thomas Schmitz-Rode, Rolf W. Günther
  • Patent number: 11160976
    Abstract: A skin treatment device is provided, which includes a needle frame in which a front end outlet of a needle that penetrates an inside thereof projects toward a front thereof, a rear end inlet of the needle is open to an outside of a rear surface thereof, and a stepped partition wall is provided in a closed shape on the outside of the rear surface thereof; a needle cover having a space portion formed on a rear thereof toward an inside thereof, a needle guide portion formed on a front surface thereof; a contact PCB configured to receive a power that is supplied from a power supply device; and a needle hub having an insertion portion formed in a front thereof toward an inside thereof.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: November 2, 2021
    Assignee: EUNSUNG GLOBAL CORP.
    Inventor: Ki Se Lee
  • Patent number: 11154656
    Abstract: An automated blood glucose control system can provide automatic delivery of glucose control therapy to a subject and receive information about manual glucose control therapy provided to the subject. The automated blood glucose control system can indicate an amount of a bolus of medicament via a control algorithm configured to control blood glucose level in the subject. The automated blood glucose control system can indicate an amount of a manual bolus of medicament, which can be used to model a diminishment of the medicament in the subject over time based at least in part on the manual bolus of medicament.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: October 26, 2021
    Assignee: Beta Bionics, Inc.
    Inventors: Firas H. El-Khatib, Edward R. Damiano, Edward B. Raskin, David Chi-Wai Lim, Michael J. Rosinko, John R. Costik
  • Patent number: 11154653
    Abstract: A syringe barrel includes a barrel body having a passage extending along a longitudinal axis between a tip opening and a load opening. The passage is configured to permit a plunger to advance therethrough along the longitudinal axis for driving a liquid through the tip opening. The barrel body includes a base portion that is configured to operably engage an injection system. The base portion has a body surface that is shaped to form a light-propagating space alongside the body surface. The light-propagating space extends to reflective ramps of the body surface. The reflective ramps have predetermined sizes and positions to reflect light signals radially away from the barrel body.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: October 26, 2021
    Assignee: Illinois Tool Works Inc.
    Inventors: Robert Schaser, Raymond Jozwik
  • Patent number: 11147918
    Abstract: A medicament delivery system configured to reduce the risk of inadvertently injecting medicament directly into a patient during a refill procedure via an external refilling apparatus. The medicament delivery system may include an implantable medical pump having a refillable medicament reservoir accessible via an access port, wherein the refillable medicament reservoir includes a flexible diaphragm having a nonlinear spring rate configured to create a relative vacuum within a medicament chamber when medicament is expelled from the medicament chamber beyond a predefined threshold, so as to spontaneously draw a quantity of medicament into the medicament chamber during the refill procedure to reestablish the predefined threshold, thereby confirming proper placement of a portion of the external refilling apparatus into the access port.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: October 19, 2021
    Assignee: Medtronic, Inc.
    Inventors: Steven Christenson, Touby Drew, James M. Haase, Scott A. Sarkinen
  • Patent number: 11147914
    Abstract: Some embodiments of an infusion pump system may be configured to wirelessly communicate with other devices using near field communication (NFC). In particular embodiments, by incorporating near field communication capabilities into the infusion pump system, user communications with the infusion pump system can be enhanced and simplified.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: October 19, 2021
    Assignee: Bigfoot Biomedical, Inc.
    Inventor: Mark C. Estes
  • Patent number: 11147480
    Abstract: Methods and devices include automated coaching for management of glucose states by receiving a user's glucose levels using a continuous glucose monitoring (CGM) device, determining a time in range (TIR) value, determining a TIR state, receiving a glucose variability (GV) value, determining a GV state, determining a starting state based on the TIR state and the GV state, determining that the starting state corresponds to a non-ideal state, generating an optimized pathway to reach an ideal state based on one or more account vectors such as addressing self-management behavior including food, activity, and medication use. The optimized pathway may further be based on computer detection and classification of significant events of interest over time.
    Type: Grant
    Filed: March 19, 2021
    Date of Patent: October 19, 2021
    Assignee: Welldoc, Inc.
    Inventors: Shiping Liu, Mansur Shomali, Abhimanyu Kumbara, Anand Iyer, Malinda Peeples, Michelle Dugas, Kenyon Crowley, Guodong Gao
  • Patent number: 11141535
    Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: October 12, 2021
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Arthur Uber, III, Chelsea Marsh, William Barone, Michael McDermott, Timothy Newing, Michael Spohn, Vince Delbrugge, Ralph Schriver, Kevin Cowan, Barry Tucker, Ronald Heller, David Griffiths, Matthew Schrauder
  • Patent number: 11136971
    Abstract: A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: October 5, 2021
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, Larry B. Gray, Russell H. Beavis, Richard J. Lanigan, Brian D. Tracey
  • Patent number: 11135373
    Abstract: The present invention proposes a liquid pharmaceuticals delivery device (18) comprising a mainly cylindrical main body (1), a cartridge (3) having a mainly cylindrical inner cavity with a volumetric capacity for accommodating multiple doses of a liquid pharmaceutical, the cartridge (3) comprising a first end for receiving a plunger (7) and a second end for liquid pharmaceutical extraction. The device (18) further comprises a jackscrew (55) a comprising a threaded lower jackscrew (5) and a threaded upper jackscrew (6) integrated or fixed to each other. The jackscrew (55) being rotatable around a primary axis of the main body (1) and stationary along said primary axis, a threaded plunger rod (8) which is integrated to the plunger (7) and which has a thread diameter (Dp) corresponding to thread diameter of the lower jackscrew (5).
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: October 5, 2021
    Assignee: Sima Patent ve Lisanslama Hizmetleri Ltd. Sti.
    Inventor: Mahmut Bilgic
  • Patent number: 11129932
    Abstract: This disclosure provides a method of determining a cartridge type of a cartridge used with a fluid drug injection system having a pump that receives a fluid drug cartridge. The fluid drug cartridge has a barrel filled with a fluid drug solution and a plunger within the barrel that forces the fluid drug solution through an outlet. An actuator of the pump is moved to contact or to move the plunger and a force sensor is used to measure force data during the movement. The force data is descriptive of the force applied to the plunger. A feature signal is determined from the force data. The feature signal can be a force modulation amplitude, a force modulation duration or a force modulation number. The cartridge type is assigned using the feature signal. Also disclosed is a fluid drug injection system and a cartridge for use therewith.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: September 28, 2021
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Thomas Meenken
  • Patent number: 11123493
    Abstract: A supplementary device for attachment to a drug delivery device is provided. The device includes an attachment mechanism for coupling the supplementary device to the drug delivery device, an imaging arrangement for providing image data representing a captured image of one or more numbers present on a number sleeve of the drug delivery device and a processor arrangement. The processor arrangement is configured to receive the image data; perform optical character recognition on the image data to determine a quantity of a currently set dose of medicament; cause display of the quantity of the currently set dose; process the image data to identify one or more characteristics of the number sleeve; determine from the identified characteristics whether the currently set dose is a permitted dose; and if the currently set dose is not a permitted dose, cause an indication that the currently set dose is not a permitted dose.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: September 21, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Stephan Riedel
  • Patent number: 11123541
    Abstract: A heart pump assembly includes an impeller blade coupled to a rotor or a drive shaft, a cannula, a distal projection coupled to a distal end of the cannula and a blood inlet having a plurality of apertures. The plurality of apertures are radially oriented and disposed about a circumference of the cannula. The plurality of apertures include at least a first ring of apertures which are proximal to the distal projection and a second ring of apertures which are proximal of the first ring of apertures. The plurality of apertures can allow the heart pump assembly to continue to function if anatomical structures or tissue become suctioned to a portion of the heart pump.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: September 21, 2021
    Assignee: ABIOMED, INC.
    Inventors: Scott C. Corbett, Ahmad El Katerji, Charles DeLorenzo
  • Patent number: 11123859
    Abstract: A magnetically driven hopping soft robot based on magnetically programmed temperature-sensitive hydrogels includes first moving bodies and a second moving body. Several first moving bodies are distributed evenly on a bottom portion of the second moving body. The first moving bodies are made of a temperature-responsive hydrogel containing magnetic particles. An alternating magnetic field is applied to the first moving bodies to cause the first moving bodies to deform due to magnetocaloric effect. The first moving bodies have a two-layered structure. A first layer is made of a double-network cross-linked hydrogel and a second layer is made of a magnetic temperature-responsive hydrogel with added magnetic nanoparticles. An alternating magnetic field is applied to the first moving bodies in a manner that an amount of deformation of the second layer is greater than that of the first layer. The second layer is made of a temperature-responsive hydrogel with added magnetic nanoparticles.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: September 21, 2021
    Assignee: Jiangsu University
    Inventors: Lin Xu, Siyuan Liu, Jianning Ding, Kun Zhang, Jiaqi Li, Chuncheng Liu, Guanggui Cheng, Zhongqiang Zhang, Xiaodong Wang
  • Patent number: 11116898
    Abstract: A system for managing a patient's glucose level includes a glucose sensor to generate and store data signals for measurements of the patient's glucose level made by the glucose sensor; an insulin pump; and sensor electronics operatively coupled to the glucose sensor, the sensor electronics comprising a memory storing one or more predetermined characteristics associated with the sensor electronics; and a computing device in electronic communication with the sensor electronics. The computing device comprises a processor configured to operate the sensor electronics to (i) receive the generated data signals, (ii) obtain the one or more predetermined sensor characteristics from the memory and (iii) execute a closed-loop algorithm to provide insulin delivery instructions to an insulin pump by at least using the data signals and predetermined characteristics.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: September 14, 2021
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Gary Alan Hayter, Erwin Satrya Budiman
  • Patent number: 11116884
    Abstract: An integrated system for assessing wound exudates from the wound of a patient is described. The system may contain functionality to detect, process and report various wound parameters. The system also may make treatment determinations based on these findings. The system may detect one or more physiological values of the wound exudates from the wound of the patient. The system may means for comparing the one or more detected physiological values to predetermined physiological values in order to obtain a comparison result in real time. The system may include a processor 15 which provides an electronic signal based on a comparison result in which the electronic signal may correspond to guidelines for treating the wound 13. The system may be integrated with other wound treatment devices, such as negative pressure wound therapy devices (NPWT) 9.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: September 14, 2021
    Assignee: ConvaTec Technologies Inc.
    Inventor: Landy Toth
  • Patent number: 11103637
    Abstract: An injector system for injecting fluid includes a syringe and an injector. The syringe includes a body and a plunger movably disposed within the body. The plunger has at least one flexible leg extending toward the rearward end of the body. The injector has a housing with a front plate, a drive member at least partially disposed within the housing and operable to engage the plunger, and a syringe release assembly operable to release the syringe. The syringe assembly includes a syringe release gear that forms an enclosure for receiving the syringe when the syringe is fully seated within the housing and a plunger release tube surrounding at least a portion of the drive member. The plunger release tube has a first end rotationally engaged with the syringe release gear. Rotation of the syringe release assembly releases the at least one flexible leg from the drive member.
    Type: Grant
    Filed: October 19, 2020
    Date of Patent: August 31, 2021
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Charles Lang, Christopher Swenglish, Luis Castillo, Stephen Schulte
  • Patent number: 11103638
    Abstract: Systems and methods presented herein relate to cancelling a modification of medicament delivery initiated by a user. A display of a therapy control element can be generated on an interface, such as a touchscreen. The therapy control element permits a user to modify a control parameter used in a control algorithm for generating a dose control signal for delivering medicament to a subject. Responsive to receiving the modification, the control parameter may be modified at a first time from a first setting to a second setting based on an indication of the modification to the therapy control element. Responsive to receiving a restore gesture on the touchscreen at a second time, the control parameter may be restored back to the first setting. This restore gesture may be a swipe gesture performed by a user.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: August 31, 2021
    Assignee: BETA BIONICS, INC.
    Inventors: Michael J. Rosinko, Edward R. Damiano, David Chi-Wai Lim, Firas H. El-Khatib, Justin P. Brown, Bryan Dale Knodel
  • Patent number: 11083839
    Abstract: An infusion arrangement for administering a medical fluid includes a pump apparatus with an elastomeric membrane which forms a pump volume. The elastomeric membrane is elastically extended in a fill state, filled at least partially with medical fluid, of the pump volume and produces a delivery pressure on the pump volume. An infusion line is connected to the pump volume and provided with a patient access for fluid-conducting connection. A main fluid channel transfers medical fluid from the pump volume to the patient access. A monitoring device is connected to the infusion line and configured for monitoring the pump apparatus. The monitoring device has a differential pressure-measuring element connected to the main fluid channel and designed such that differential pressure formed along a channel portion of the main fluid channel can be detected by the differential pressure-measuring element and a delivery rate of the medical fluid can be indicated.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: August 10, 2021
    Assignee: B. BRAUN MELSUNGEN AG
    Inventors: Karsten Haslbeck, Jens Wildhagen
  • Patent number: 11065384
    Abstract: An administration set for an infusion pump includes a free-flow prevention device having a movable plunger that includes a cam surface defining an uneven profile along a direction of movement of the plunger, wherein the shape of the cam surface profile indicates the administration set is authorized for use with the infusion pump and may further indicate the specific type of administration set. A sensor in the infusion pump senses movement of the plunger as a platen of the infusion pump is latched and generates a profile signal in the time domain representative of the cam surface profile. A processor evaluates the profile signal and controls operation of the pump to protect a patient from improper loading of an administration set, use of an unauthorized administration set, and/or use of an invalid type of administration set for a chosen infusion protocol.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: July 20, 2021
    Assignee: Curlin Medical Inc.
    Inventors: Azur Azapagic, Mohan Jonathan Barkley
  • Patent number: 11065381
    Abstract: A patch pump including a medicament reservoir having an inner surface defining an elongate piston engagement pathway, an electric motor having a rotary drive output element, a piston replaceably axially fixed to the electric motor. The piston having an outer surface arranged for sealing engagement with the inner surface of the medicament reservoir, the piston also including a rotary to longitudinal drive converter receiving a rotary drive input from the rotary drive output element of the electric motor and providing a longitudinal drive to the reservoir, thereby driving the medicament reservoir in longitudinal motion relative to the piston in which the elongate piston engagement pathway defined by the inner surface of the medicament reservoir is displaced axially and in sealing engagement with the outer surface of said piston.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: July 20, 2021
    Assignee: E3D A.C.A.L.
    Inventors: Ziv Naftalovitz, Ilan Shopen, Tsachi Shaked
  • Patent number: 11040137
    Abstract: A drug delivery device includes a housing component having an interior space and an exterior surface, an injection needle having a retracted state wherein the needle is hosted inside of the interior space and a deployed state wherein a pointed end of the needle projects beyond the exterior surface of the housing component, a needle drive mechanism coupled to the needle to move the needle between the retracted and deployed states, and a drug container disposed within the interior space. The drug container is pre-filled with sterile liquid drug and to be in fluid communication with the needle. The sterile liquid drug herein might be solution, suspension, emulation or other forms in fluid state. The drug delivery device also includes a microcontroller coupled to the needle drive mechanism. The microcontroller is configured to control the needle drive mechanism to move the needle between the retracted state and the deployed state. Further, the delivery device is wearable, disposable, and single-use.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: June 22, 2021
    Inventor: Min Wei
  • Patent number: 11034926
    Abstract: Systems and methods for improved flow properties in fluidic and microfluidic systems are disclosed. The system includes a microfluidic device having a first microchannel, a fluid reservoir having a working fluid and a pressurized gas, a pump in communication with the fluid reservoir to maintain a desired pressure of the pressurized gas, and a fluid-resistance element located within a fluid path between the fluid reservoir and the first microchannel. The fluid-resistance element includes a first fluidic resistance that is substantially larger than a second fluidic resistance associated with the first microchannel.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: June 15, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Christopher David Hinojosa, Josiah Sliz, Daniel Levner, Guy Thompson, Hubert Geisler, Jose Fernandez-Alcon, Donald E. Ingber
  • Patent number: 11033686
    Abstract: An administration mechanism for a medicament delivery device is disclosed having a linearly displaceable medicament delivery member cover, an actuator sleeve, an actuator, wherein the medicament delivery member cover is configured to axially displace the actuator sleeve from an initial position to a distally displaced position thereby displacing the actuator sleeve relative to the actuator, a rotator having a guide structure, a plunger holder, and a plunger rod that is proximally biased. The actuator can engage with the plunger holder in the initial position of the actuator sleeve to prevent the plunger holder from proximal displacement relative to the actuator. The actuator can be released from engagement with the plunger holder by displacement of the actuator sleeve towards the distally displaced position to enable proximal displacement of the plunger holder, the plunger rod and the rotator relative to the actuator.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: June 15, 2021
    Assignee: SHL MEDICAL AG
    Inventor: Oscar Alexandersson
  • Patent number: 10994114
    Abstract: A fluid pathway connection includes a piercing member, a connection hub, and a sliding pierceable seal, wherein the sliding pierceable seal is configured to move from a first position, where the piercing member is initially retained within a sterile cavity between the connection hub and the sliding pierceable seal, to a second position, where the pierceable seal has been penetrated by the piercing member. A filter may be utilized to enclose the sterile cavity from the outside environment. The fluid pathway connection may further be configured to move to a third position where one or more interconnects and/or one or more corresponding contacts are permitted to transmit a signal to the user. Such fluid pathway connections may be integrated into a drug container having a barrel and a plunger seal. A drug delivery pump includes such integrated fluid pathway connections and drug containers.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: May 4, 2021
    Assignee: UNL Holdings LLC
    Inventors: Matthew J. Clemente, Ian B. Hanson, Paul F. Bente, IV, Ryan M. Agard, Nicholas J. Ciccarelli