Treating Material Forced Into Or Out Of Body By Self-acting Fluid Pressure, Motor-driven, Or Mechanical Energy Storing Means (e.g., Pressure Infusion Or Aspiration, Etc.) Patents (Class 604/131)
  • Patent number: 11065381
    Abstract: A patch pump including a medicament reservoir having an inner surface defining an elongate piston engagement pathway, an electric motor having a rotary drive output element, a piston replaceably axially fixed to the electric motor. The piston having an outer surface arranged for sealing engagement with the inner surface of the medicament reservoir, the piston also including a rotary to longitudinal drive converter receiving a rotary drive input from the rotary drive output element of the electric motor and providing a longitudinal drive to the reservoir, thereby driving the medicament reservoir in longitudinal motion relative to the piston in which the elongate piston engagement pathway defined by the inner surface of the medicament reservoir is displaced axially and in sealing engagement with the outer surface of said piston.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: July 20, 2021
    Assignee: E3D A.C.A.L.
    Inventors: Ziv Naftalovitz, Ilan Shopen, Tsachi Shaked
  • Patent number: 11065384
    Abstract: An administration set for an infusion pump includes a free-flow prevention device having a movable plunger that includes a cam surface defining an uneven profile along a direction of movement of the plunger, wherein the shape of the cam surface profile indicates the administration set is authorized for use with the infusion pump and may further indicate the specific type of administration set. A sensor in the infusion pump senses movement of the plunger as a platen of the infusion pump is latched and generates a profile signal in the time domain representative of the cam surface profile. A processor evaluates the profile signal and controls operation of the pump to protect a patient from improper loading of an administration set, use of an unauthorized administration set, and/or use of an invalid type of administration set for a chosen infusion protocol.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: July 20, 2021
    Assignee: Curlin Medical Inc.
    Inventors: Azur Azapagic, Mohan Jonathan Barkley
  • Patent number: 11040137
    Abstract: A drug delivery device includes a housing component having an interior space and an exterior surface, an injection needle having a retracted state wherein the needle is hosted inside of the interior space and a deployed state wherein a pointed end of the needle projects beyond the exterior surface of the housing component, a needle drive mechanism coupled to the needle to move the needle between the retracted and deployed states, and a drug container disposed within the interior space. The drug container is pre-filled with sterile liquid drug and to be in fluid communication with the needle. The sterile liquid drug herein might be solution, suspension, emulation or other forms in fluid state. The drug delivery device also includes a microcontroller coupled to the needle drive mechanism. The microcontroller is configured to control the needle drive mechanism to move the needle between the retracted state and the deployed state. Further, the delivery device is wearable, disposable, and single-use.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: June 22, 2021
    Inventor: Min Wei
  • Patent number: 11033686
    Abstract: An administration mechanism for a medicament delivery device is disclosed having a linearly displaceable medicament delivery member cover, an actuator sleeve, an actuator, wherein the medicament delivery member cover is configured to axially displace the actuator sleeve from an initial position to a distally displaced position thereby displacing the actuator sleeve relative to the actuator, a rotator having a guide structure, a plunger holder, and a plunger rod that is proximally biased. The actuator can engage with the plunger holder in the initial position of the actuator sleeve to prevent the plunger holder from proximal displacement relative to the actuator. The actuator can be released from engagement with the plunger holder by displacement of the actuator sleeve towards the distally displaced position to enable proximal displacement of the plunger holder, the plunger rod and the rotator relative to the actuator.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: June 15, 2021
    Assignee: SHL MEDICAL AG
    Inventor: Oscar Alexandersson
  • Patent number: 11034926
    Abstract: Systems and methods for improved flow properties in fluidic and microfluidic systems are disclosed. The system includes a microfluidic device having a first microchannel, a fluid reservoir having a working fluid and a pressurized gas, a pump in communication with the fluid reservoir to maintain a desired pressure of the pressurized gas, and a fluid-resistance element located within a fluid path between the fluid reservoir and the first microchannel. The fluid-resistance element includes a first fluidic resistance that is substantially larger than a second fluidic resistance associated with the first microchannel.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: June 15, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Christopher David Hinojosa, Josiah Sliz, Daniel Levner, Guy Thompson, Hubert Geisler, Jose Fernandez-Alcon, Donald E. Ingber
  • Patent number: 10994114
    Abstract: A fluid pathway connection includes a piercing member, a connection hub, and a sliding pierceable seal, wherein the sliding pierceable seal is configured to move from a first position, where the piercing member is initially retained within a sterile cavity between the connection hub and the sliding pierceable seal, to a second position, where the pierceable seal has been penetrated by the piercing member. A filter may be utilized to enclose the sterile cavity from the outside environment. The fluid pathway connection may further be configured to move to a third position where one or more interconnects and/or one or more corresponding contacts are permitted to transmit a signal to the user. Such fluid pathway connections may be integrated into a drug container having a barrel and a plunger seal. A drug delivery pump includes such integrated fluid pathway connections and drug containers.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: May 4, 2021
    Assignee: UNL Holdings LLC
    Inventors: Matthew J. Clemente, Ian B. Hanson, Paul F. Bente, IV, Ryan M. Agard, Nicholas J. Ciccarelli
  • Patent number: 10987465
    Abstract: A vibrational injection apparatus suitable for use in a system for removal, delivery and/or transplantation of body tissues and other substances in medical procedures may include an apparatus housing. A vibration mechanism may be provided in the apparatus housing. A material injector may be provided in the apparatus housing and mechanically coupled to the vibration mechanism. An injection cannula may be disposed in fluid communication with the material injector.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: April 27, 2021
    Inventors: Simeon Wall, Jr., Daniel A. Del Vecchio
  • Patent number: 10973978
    Abstract: A fluid flow regulator of a fluid delivery system that can adjust a flow rate of a liquid drug dispensed from a liquid drug container to a user is provided. The fluid flow regulator can be coupled to an end of the liquid drug container. The fluid flow regulator can include a compliance plate and a flow channel selector plate having a fluid flow channel. The flow channel selector plate can be rotated relative to the compliance plate and the liquid drug container to expose a selected portion of the fluid flow channel to openings in the compliance plate that are in fluid communication with the liquid drug stored in the liquid drug container. The selected portion of the fluid flow channel can correspond to a corresponding flow resistance of the liquid drug through the fluid flow channel, thereby regulating the flow of the liquid drug to the user.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: April 13, 2021
    Assignee: INSULET CORPORATION
    Inventors: David Nazzaro, Ian McLaughlin, Daniel Allis, Jason O'Connor
  • Patent number: 10960143
    Abstract: In an elongated casing, an active agent container connected to an injection needle can be shifted axially by a spring force. Auto-injectors which are sold or distributed filled and with the springs tensed have to be provided with a needle protecting cap to ensure the sterility of the injection needle. When such a needle protecting cap is removed as preparation for using the auto-injector, a tensile force can be exerted on the active agent container. Therefore, the active agent container comprising the injection needle must be prevented from being undesirably pulled forwards. At least one latching tongue prevents the active agent container from being prematurely shifted with respect to the casing, by abutting a flange arranged on a sliding sleeve which accommodates the active agent container. When the auto-injector is placed onto a person's skin, a needle protecting tube is shifted into the casing, forcing the latching tongue away from the flange and, thus, freeing the travel path for needle movement.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: March 30, 2021
    Assignee: Ypsomed AG
    Inventors: Edgar Hommann, Benjamin Scherer
  • Patent number: 10964428
    Abstract: Various techniques for facilitating communication with and across a clinical environment and a cloud environment are described. For example, a method for generating a user interface based on messages from a clinical environment is described. A data flow manager (DFM) in the cloud environment may check whether the information in a message received from a connectivity adapter in the clinical environment can be used to generate a user interface (UI). If the information can be used to generate a UI, the DFM may merge the information into the cache. The information merged into the cache can subsequently be used to generate a UI in response to a user request.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: March 30, 2021
    Assignee: ICU MEDICAL, INC.
    Inventors: Ben Xavier, Dennis Krabbe, Larry Enger, Chaitanya Deosthale, Anthony Isensee
  • Patent number: 10937537
    Abstract: A computer-implemented method includes establishing a communications link, via a short-range wireless protocol, between a mobile computing device and a medicament delivery device. A user input selecting a motion profile of the medicament delivery device is then received in response to an input prompt. A wireless signal is received from the medicament delivery device, the wireless signal associated with an actual motion profile of the medicament delivery device. A notification is produced to indicate a motion difference between the actual motion profile and the target motion profile. In some embodiments, the method optionally includes modifying the target motion profile based on the motion profile over a time period of at least one week, the notification indicating a motion difference between the motion profile and the modified target motion profile.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: March 2, 2021
    Assignee: kaleo, Inc.
    Inventors: Eric S. Edwards, Evan T. Edwards, Paul F. Meyers, Samuel Jefferson Briggs, George McGee Perkins, Eugene Johannes Van Wyk, Mitchell Frederick Burke, Eric William Scammell
  • Patent number: 10918787
    Abstract: A disposable electronically controlled infusion pump system includes at least one disposable infusion container and at least one disposable electronically controlled medication pumping system. The at least one disposable infusion container is configured to contain infusion fluid. The at least one disposable electronically controlled medication pumping system is fluidly connected in the at least one disposable infusion container. The at least one disposable electronically controlled medication pumping system includes an infusion channel, a disposable electronically controlled micropump, and valves, but may further include a microprocessor, a memory, a battery or a power receiver configured to wirelessly receive power, a wireless communication device, and other components. The wireless communication device is configured to receive a wireless signal which wirelessly controls the at least one disposable electronically controlled medication pumping system.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: February 16, 2021
    Assignee: ICU Medical, Inc.
    Inventors: Gary David Shubinsky, Thomas D. Johnson, Jeffrey Donald Merwin, Vlad Radu Balteanu
  • Patent number: 10894124
    Abstract: A syringe includes a body and a plunger movably disposed within the body. The syringe may be used with an injector including a drive member. The drive member preferably includes at least one pin adapted to form a retractable abutting connection with an interior of a plunger to enable the drive member to retract the plunger with the body of the syringe.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: January 19, 2021
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Kevin Cowan, John Haury, Jared Neff
  • Patent number: 10881801
    Abstract: A cartridge adapter includes: a cartridge holder having a space that can accommodate therein a drug cartridge, the drug cartridge including a cylinder having a tubular internal space extending in a longitudinal direction, a gasket supported in the internal space so as to be movable in the longitudinal direction, and a drug held in the internal space; a piston that moves the gasket in the longitudinal direction in the internal space of the cylinder; a piston guide that movably supports the piston and connected to the cartridge holder; and a piston driving mechanism that drives the piston in the longitudinal direction.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: January 5, 2021
    Assignee: PHC HOLDINGS CORPORATION
    Inventors: Kenji Murakami, Mitsuteru Fujimoto, Seiji Kikuchi, Toru Aoki, Masakazu Mori, Ryosuke Tani, Shinichi Kojima, Yoshihiro Kataoka, Katsumi Nakanishi, Tsuguhiro Kondo, Takashi Morimoto, Akio Inoki
  • Patent number: 10874804
    Abstract: A medicament delivery device includes a housing having proximal and distal ends; a delivery member connected to the housing; a medicament container operably arranged within the housing; a drive mechanism configured to act on the medicament container for priming and for expelling a dose of medicament; and an activator mechanism configured to interact with the drive mechanism, such that a first interaction between the activator mechanism and the drive mechanism causes the container to move toward the delivery member, in which the container is primed, and such that a subsequent interaction between the activator mechanism and the drive mechanism causes a dose of medicament to be expelled through the delivery member.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: December 29, 2020
    Assignee: SHL MEDICAL AG
    Inventors: Lucio Giambattista, Antonio Bendek, Mattias Daniel, Sebastian Karlsson
  • Patent number: 10874767
    Abstract: The invention provides methods and polymer compositions for treating retinal detachment and other ocular disorders, where the methods employ polymer compositions that can form a hydrogel in the eye of a subject. The hydrogel is formed by reaction of (i) a nucleo-functional polymer that is a biocompatible polymer containing a plurality of thio-functional groups —R1—SH wherein R1 is an ester-containing linker, such as a thiolated poly(vinyl alcohol) polymer and (ii) an electro-functional polymer that is a biocompatible polymer containing at least one thiol-reactive group, such as a poly(ethylene glycol) polymer containing alpha-beta unsaturated ester groups.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: December 29, 2020
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: James Anthony Stefater, III, Tomasz Pawel Stryjewski
  • Patent number: 10856933
    Abstract: A surgical device includes a housing, at least one electrical wire, a shaft, and an end effector assembly. The housing defines an interior cavity and first and second housing portions. The first and second housing portions are configured to engage one another to enclose the interior cavity. A channel is defined within an outer perimeter of the first and/or second housing portion such that engagement of the first and second housing portions encloses the channel separate from the interior cavity. The electrical wire(s) is housed within the channel and adapted to connect to a source of energy. The shaft is coupled to the housing and extends distally therefrom. The end effector assembly is disposed at a distal end of the shaft, wherein the end effector assembly is electrically coupled to the at least one electrical wire for supplying energy to the end effector assembly.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: December 8, 2020
    Assignee: COVIDIEN LP
    Inventor: James D. Allen, IV
  • Patent number: 10861592
    Abstract: A system can include a plurality of infusion pumps and a connectivity adapter in a clinical environment. The connectivity adapter can receive update data, such as a drug library update or an operational software update, and can store the update data within the clinical environment. The connectivity adapter can send the update data to a predetermined number of infusion pumps that have requested the update. At least two subsets of the infusion pumps can receive different blocks of the update data at about the same time. Further, the same or different update data can be provided to the infusion pumps at about the same time.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: December 8, 2020
    Assignee: ICU Medical, Inc.
    Inventors: Ben Xavier, Dennis Krabbe, Larry Enger, Chaitanya Deosthale, Anthony Isensee
  • Patent number: 10857309
    Abstract: A portable liquid medicine administration device for continuous or intermittent administration of a liquid medicine into a living body includes: a liquid medicine administration device main body filled with the liquid medicine; and a cradle to which the liquid medicine administration device main body is attachable and detachable. The liquid medicine administration device main body includes: an alarm unit configured to output an alarm on a basis of a notification event occurring while the liquid medicine administration device main body is attached to the cradle; and an alarm control unit configured to stop the alarm on a basis of a change occurring in a relative position between the cradle and the liquid medicine administration device main body.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: December 8, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Shohei Sasaki
  • Patent number: 10850028
    Abstract: A skin attachable drug injection device (1), comprising an accelerometer (26) able to detect the user tapping against the housing (2) of the device and to generate an electrical signal to the device controller (16), which recognizes the signal as a user request for information regarding the ongoing delivery of the medicament, and a transmitter (30) which in response wirelessly transmits said information (e.g. the expected remaining during of the injection) to a separate portable user device having a display (e.g. mobile phone). A user carrying the injection device under clothing can thus receive feedback about the status of the injection in a discreet way.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: December 1, 2020
    Assignee: Sanofi
    Inventor: Michael Caspers
  • Patent number: 10828430
    Abstract: A medicinal-liquid administering device is for administering medicinal liquid filling a tubular body into a living body under a pressing action of a plunger. The medicinal-liquid administering device includes: a disposable part including: the tubular body, the plunger, and a movable part configured to be moved from an initial position and to press the plunger toward a distal-end side; a reusable part that is attachable to and detachable from the disposable part, the reusable part including: at least part of a driving part configured to move the movable part, a first position detection sensor configured to detect whether or not the movable part is at the initial position in a state before the movable part is moved, and an alarm part configured to output a first alarm when the first position detection sensor detects that the movable part is not at the initial position.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: November 10, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Akira Kondo
  • Patent number: 10828417
    Abstract: Ambulatory infusion pumps, pump assemblies, and disposable assemblies, including cartridges, baseplates, cannulas, inserters, and related components therefor, as well as component combinations and related methods.
    Type: Grant
    Filed: December 2, 2017
    Date of Patent: November 10, 2020
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Roger E. Smith, Scott R. Gibson
  • Patent number: 10799631
    Abstract: An automatic injection device has an insertion needle configured to be inserted into a patient and a drug container which contains a pharmaceutical product. The drug container includes a plunger. The automatic injection device also has a fluid path which fluidly connects the drug container to the insertion needle. The automatic injection device further has a drive system configured to cause linear movement of the plunger to force the pharmaceutical product into the fluid path. The drive system has a driving element and a movable element. The automatic injection device additionally has electronics configured to provide a signal to the drive system to move the plunger. The movable element has an outer magnet at least partially surrounding the drug container and an inner magnet inside the drug container.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: October 13, 2020
    Assignee: FLEXTRONICS AP, LLC
    Inventors: Eyal Barmaimon, Lior Shtram, Boaz Kalisch, Ronny Bellan, Nadav Cohen, Shai Finkman, Yuval Harel
  • Patent number: 10792440
    Abstract: An infusion pump system is disclosed. The system includes at least one infusion pump, a companion device, the companion device in wireless communication with the infusion pump, and a user interface on the companion device, the user interface adapted to receive textual input.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: October 6, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Marc A. Mandro, Geoffrey P. Spencer, Robert J. Bryant, Jr., Patricia M. Armstrong
  • Patent number: 10780220
    Abstract: A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: September 22, 2020
    Assignee: DEKA Products Limited Partnership
    Inventor: Larry B. Gray
  • Patent number: 10765361
    Abstract: Devices are provided to automatically inject drugs or other payloads into or beneath skin. These devices include an injector configured to drive a hollow needle into the skin and subsequently to deliver the payload through the hollow needle. Applied suction acts to draw blood from the puncture formed in the skin through the hollow needle, into the device, and to a sensor, blood storage element, or other payload. In some examples, the blood is drawn through the hollow needle when the hollow needle is penetrating the skin. In some examples, these devices are additionally configured to retract the hollow needle from the skin and/or to perform some other functions. These devices can be wearable and configured to automatically access blood or deliver a payload into skin, for example, to operate at one or more points in time while a wearer of a device is sleeping.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: September 8, 2020
    Assignee: Verily Life Sciences LLC
    Inventors: Benjamin David Krasnow, Eric Peeters, Peter Howard Smith
  • Patent number: 10744271
    Abstract: A medicine delivery device includes a main housing having a guide rail in a bottom side thereof, a main control unit with built-in control program mounted in the main housing, a transmission module mounted in the main housing and electrically coupled to the main control unit, the transmission module including a transmission unit, transmission shaft rotatable by the transmission unit and a push rod threaded into the transmission shaft with an axial guide groove thereof coupled to the guide rail for axial displacement upon rotation of the transmission shaft, a push-button unit mounted on the outer surface of the main housing and electrically coupled to the main control unit, and a power supply unit mounted in the main housing for providing the main control unit with the necessary working electricity.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: August 18, 2020
    Assignee: DUO-KANG CO., LTD.
    Inventor: Yung-Fu Lee
  • Patent number: 10744264
    Abstract: An autoinjector having a body (1) adapted to receive a reservoir containing fluid and including a piston (P) and a needle. The body (1) has a distal portion, a middle portion, and a proximal portion, the middle portion including at least one middle window (12) making it possible, before use, to see 100% of the fluid contained in the reservoir and, after injection, to see the piston (P). The middle window (12) has an external shape of an arrow that points towards the proximal portion. The proximal portion (121) of the middle window (12) includes a triangular end portion, forming the point of the arrow, the base of the triangular end portion, remote from the point, forms the widest portion of the middle window (12).
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: August 18, 2020
    Assignee: APTAR FRANCE SAS
    Inventors: Anthony Saussaye, Franck Foucault, Philippe Pinheiro
  • Patent number: 10737023
    Abstract: Systems and methods are provided for signaling a condition of an infusion assembly. A system may comprise an elastomeric pump that includes a chamber for receipt of a volume of fluid, an outer layer configured to expand and contract as the chamber receives and dispenses fluid, and a passive indicator provided on the outer layer for signaling a change in the volume of fluid in the chamber. The system further may comprise an image capture device configured to capture an image of the pump, and a processing system configured to process the image to signal the condition of the infusion assembly to a user of the system. A method may comprise capturing an image of a pump; processing the image; and displaying information to a user of the pump to communicate the condition of the pump to the user. Elastomeric pumps for infusion assemblies also are provided.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: August 11, 2020
    Assignee: Avent, Inc.
    Inventors: Bao-Tram N. Pham, Justin J. Coker, Shane A. Duffy, Judith Davenport, Kenneth C. Hsu, Ryan Massengale
  • Patent number: 10729618
    Abstract: A liquid medicine filling device includes a container mounting unit, a liquid delivery flow conduit, a ventilation flow conduit, a syringe, a connection flow conduit, a first flow path switching unit, and a second flow path switching unit. The first flow path switching unit may switch between a flow path for filling through which the syringe communicates with a liquid medicine container via the ventilation flow conduit and a flow path for air removal through which the syringe communicates with the connection flow conduit via the ventilation flow conduit. The second flow path switching unit may switch between a flow path for filling through which the liquid medicine container communicates with the liquid medicine storage unit via the liquid delivery flow conduit and a flow path for air removal through which the liquid medicine storage unit communicates with the connection flow conduit via the liquid delivery flow conduit.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: August 4, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Mitsutoshi Yaegashi
  • Patent number: 10729841
    Abstract: A femoral hip joint spacer including a prosthesis body having a ball head with a sliding surface, a neck, a collar and a stem. A fastening area is arranged on the stem. The femoral hip joint spacer further has a first connector for feeding a medical irrigation liquid into the body, a second connector for draining the irrigation liquid from the body, and an irrigation liquid inlet opening. The first connector is connected in a liquid-conveying manner to the irrigation liquid inlet opening and an irrigation liquid outlet opening. The second connector is connected in a liquid-conveying manner to the irrigation liquid outlet opening, an irrigation liquid discharge opening and an irrigation liquid intake opening. The irrigation liquid discharge opening is connected inside the body to the irrigation liquid inlet opening and the irrigation liquid intake opening is connected inside the body to the irrigation liquid outlet opening.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: August 4, 2020
    Assignee: Heraeus Medical GmbH
    Inventors: Sebastian Vogt, Thomas Kluge
  • Patent number: 10722661
    Abstract: A medical remote controller device is disclosed. The device includes a display and at least one input switch dedicated to bolus delivery wherein a bolus delivery is programmed when the input switch receives an input and wherein the number of inputs received by the input switch determines the amount of bolus to be delivered.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: July 28, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Marc A. Mandro, Geoffrey P. Spencer, Robert J. Bryant, Jr., Patricia M. Armstrong
  • Patent number: 10716901
    Abstract: An auto-injector operable in a single activation step. The auto-injector is automatically armed when removed from its carrying receptacle. The auto-injector may be prefilled with more than one constituent of a beneficial agent, stored in separated compartments, in such an arrangement that the compartments will automatically merge when the auto-injector is removed from its carrying receptacle.
    Type: Grant
    Filed: December 5, 2015
    Date of Patent: July 21, 2020
    Assignee: AKTIVAX, Inc.
    Inventor: Amir Genosar
  • Patent number: 10695506
    Abstract: A drug injection device (10) including a housing (12) for holding a container (20) having a needle (24) for penetrating skin and a plunger (42) for expelling a drug stored in the container. The device includes visual and/or audible indicators for indicating that the correct depth of needle penetration has been achieved and that drug injection/extrusion has been started and/or completed. The device may further include a label (140) for visually confirming the quality of the drug contained therein. Alternatively, a tray (110) may be provided for receiving the drug injection device, which allows the quality of the drug contained therein to be visually confirmed.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: June 30, 2020
    Assignee: AMGEN INC.
    Inventors: Peter V. Shultz, Christopher R. Folk, Sigrid Moeslinger, Masamichi Udagawa, Molly Evans, Lin Gao, Lisa Nugent
  • Patent number: 10695487
    Abstract: A controlled delivery drive mechanism includes a drive housing, a piston, and a biasing member initially retained in an energized state and is configured to bear upon an interface surface of the piston. The piston is configured to translate a plunger seal and a barrel. A tether is connected between the piston and the winch drum to restrain the free expansion of the biasing member and the free axial translation of the piston upon which the biasing member bears upon. The drive mechanism may further include a gear assembly and an escapement regulating mechanism configured to control the rotation of the gear assembly to release the tether from the winch drum. The metering of the tether by the escapement regulating mechanism controls the rate or profile of drug delivery to a user.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: June 30, 2020
    Assignee: UNL Holdings LLC
    Inventors: Ian B. Hanson, Paul F. Bente, IV, Mark A. Destefano
  • Patent number: 10695477
    Abstract: A circulatory assist system is disclosed, the system including an implantable electrical device having an electric motor, an implantable controller connected to the implantable electrical device, and an implantable power source connected to the controller for supplying power to the controller. The controller is attachable to a first side of a percutaneous connector. A second side of the percutaneous connector, opposite to the first side, allows external connectivity to said controller.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: June 30, 2020
    Assignee: HeartWare, Inc.
    Inventors: Barry M. Yomtov, John Robert Batty, Jr., Daniel Tamez
  • Patent number: 10688233
    Abstract: Methods and systems for processing biological fluid are disclosed. The methods and systems allow for processing of biological fluid to continue in the event that certain non-operator-correctable hardware errors of a non-critical nature are detected during such processing.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 23, 2020
    Assignee: Fenwal, Inc.
    Inventors: Amit J. Patel, Samantha M. Planas, Melissa A. Thill
  • Patent number: 10688294
    Abstract: A fluid delivery system includes a first container configured for storing a first fluid therein and a second container configured for storing a second fluid therein, wherein the second fluid is different from the first fluid. The fluid delivery system further includes at least one pump configured for delivering under pressure one or both of the first and second fluids. At least one valve is provided for selectively delivering one or both of the first and second fluids to the pump. The first and second containers, the pump, and the valve are contained within a cartridge that is removably insertable into a cartridge carrier of the fluid delivery system.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: June 23, 2020
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Kevin P. Cowan, Mark Trocki, Arthur E. Uber, III
  • Patent number: 10688243
    Abstract: A cartridge insertion assembly including apparatus with a pathway formed therein, a cartridge including a cartridge coupling element connectable to an activation mechanism disposed in the apparatus operative to cause a substance contained in the cartridge to be metered out of the cartridge, and a door pivoted to the apparatus that includes a door coupling element arranged with respect to the cartridge such that when the door is in a fully closed position, the door coupling element couples the cartridge coupling element with a coupling element of the activation mechanism.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: June 23, 2020
    Assignee: WEST PHARMA. SERVICES IL, LTD.
    Inventor: Oz Cabiri
  • Patent number: 10682458
    Abstract: a flow pathway subassembly (264, 278) including medicament flow pathway components of a medical device, and a holder (270, 280) configured for holding the components so that a center of gravity of the subassembly is disposed substantially on a central longitudinal axis of the subassembly.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: June 16, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Haiming Wu, Danial P. Ferreira
  • Patent number: 10682464
    Abstract: A drive mechanism of an injection device for setting and dispensing of a dose of a medicament includes a body accommodating a cartridge filled with a medicament, an insert axially displaceable inside the body between a proximal operating position and a distal reset position, a piston rod to operably engage with a piston of the cartridge, a drive sleeve rotationally coupled with the piston rod and is rotationally lockable to the body for setting of a dose and rotationally releasable from the body for dispensing of a dose, respectively. The drive sleeve is axially displaceable relative to the body from a proximal operating position into a distal reset position through an axial connection of the insert and the drive sleeve, where the drive sleeve is rotationally released from the body when in the distal reset position.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: June 16, 2020
    Assignee: Sanofi
    Inventors: Joseph Butler, Paul Richard Draper
  • Patent number: 10661067
    Abstract: An injection instrument including a hollow needle body including a substrate having a first surface and a second surface opposite to the first surface, the hollow needle body having at least one projection which is formed on the first surface and has a through hole penetrating from a distal end of the at least one projection to the second surface of the substrate, a deforming member positioned outside a region where the at least one projection is formed, the deforming member being deformable to bulge in a bulging direction along a projecting direction of the at least one projection beyond a plane flush with the first surface, and a pressure channel through which a fluid is supplied such that a fluid pressure is applied to the deforming member. The deforming member is deformable in the bulging direction in response to the fluid pressure.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: May 26, 2020
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventor: Yoshihiro Kodama
  • Patent number: 10639418
    Abstract: A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: May 5, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, Larry B. Gray
  • Patent number: 10632255
    Abstract: A method and apparatus are provided for providing a plurality of injections from a fluid reservoir. The apparatus includes a fluid controller for controlling the flow of fluid from the fluid reservoir to a needle. An actuator selectively actuates the fluid controller to provide a dose of medicament from the fluid reservoir. The fluid controller also is configured to calculate the volume of fluid in the fluid reservoir required to provide a dose having a desired number of units of medicament for an injection. The apparatus may also include a detector configured to detect a characteristic indicative of the fluid pressure in the needle. The method includes selecting the number of units to be dispensed during an injection, automatically calculating the injection volume required to dispense the selected number of units based on the calculated unit volume and tracking the total number of units dispensed during a series of injections.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: April 28, 2020
    Assignee: MILESTONE SCIENTIFIC, INC.
    Inventors: Mark N. Hochman, Nathan J. Inkrote, Robert D. Boyer, Maureen A. Mullins
  • Patent number: 10610324
    Abstract: A stereotactic device of the present disclosure includes a base seat, a first moving module, a second moving module, a supporting module, and an operating module. The first moving module is disposed on the base seat and moves along a first direction, and the second moving module is disposed on the first moving module and moves along a second direction substantially perpendicular to the first direction. The supporting module is disposed on the second moving module and includes a supporting unit, and a grip unit that is disposed on the supporting unit. The operating module is disposed on the supporting module and includes a support unit, a rotating unit that is disposed on the support unit, a driving unit that is disposed on the support unit and that is co-movable with the rotating unit, and a sliding unit that is co-movable with the driving unit.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: April 7, 2020
    Inventor: Chao-Hsien Chen
  • Patent number: 10607732
    Abstract: Provided are a wearable personal digital device and related methods. The wearable personal digital device may comprise a processor, a display, biometric sensors, activity tracking sensors, a memory unit, a communication circuit, a housing, an input unit, a projector, a timepiece unit, a haptic touch control actuator, and a band. The processor may be operable to receive data from an external device, provide a notification to a user based on the data, receive a user input, and perform a command selected based on the user input. The communication circuit may be communicatively coupled to the processor and operable to connect to a wireless network and communicate with the external device. The housing may be adapted to enclose the components of the wearable personal digital device. The band may be adapted to attach to the housing and secure the wearable personal digital device on a user body.
    Type: Grant
    Filed: March 10, 2019
    Date of Patent: March 31, 2020
    Inventors: Zhou Tian Xing, Andrew H B Zhou, Tiger T G Zhou
  • Patent number: 10603415
    Abstract: In one embodiment, system for real time monitoring of catheter aspiration includes a housing having a first port adapted for connection to a vacuum source and a second port adapted for connection with an aspiration catheter, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold. In another embodiment, the system for real time monitoring of catheter aspiration further includes a vacuum source for connection to the first port and an aspiration catheter having an aspiration lumen for connection to the second port.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: March 31, 2020
    Assignee: Incuvate, LLC
    Inventors: David M. Look, Bradley S. Culbert
  • Patent number: 10596308
    Abstract: The present invention relates to a blood treatment cassette having a cassette body, embodied as a hard part, and a film, wherein the film is connected with the hard part and covers the hard part at least partially, wherein the hard part comprises at least one valve seat or valve section or one valve base of a valve, wherein the valve is embodied to take, in addition to a first, open position of the valve in which the valve base and the section of the film positioned above it do not touch each other, a second, closed position of the valve when applying force on the section of the film and wherein the valve base, in its longitudinal extension, comprises or is a non-straight section. The present invention also relates to a blood treatment apparatus connected with a blood treatment cassette.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: March 24, 2020
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Martin Lauer
  • Patent number: 10576213
    Abstract: The present invention relates to a medicament delivery device comprising: a housing; a drive mechanism arranged to act on a plunger rod; a release mechanism interactively connected to the drive mechanism for releasing the drive mechanism from a pre-tensioned state; and a signal generating mechanism for generating an audible and/or tactile and/or visual signal indicating that a medicament has been completely delivered. The signal generating mechanism is operably connected to said drive mechanism such that it is arranged movable in a longitudinal direction in relation to said drive mechanism. Said drive mechanism is arranged with a signal release mechanism capable of activating said signal generating mechanism at a certain longitudinal position of said drive mechanism after its release, for generating an audible and/or tactile and/or visual signal. Said signal generating mechanism comprises a signal delay mechanism.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: March 3, 2020
    Assignee: SHL MEDICAL AG
    Inventor: Stefan Gylleby
  • Patent number: 10543348
    Abstract: A method of using a vibrating gastrointestinal capsule in coordination with an ingestible medicament for treatment of an ailment of the GI tract. The vibrating gastrointestinal capsule, is provided to the subject, and includes: a housing; a vibrating agitation mechanism causing the housing to exert vibrations on an environment thereof; a power supply for powering said vibrating agitation mechanism; and a control mechanism for activating said vibrating agitation mechanism to operate in said vibration mode of operation. The subject ingests the ingestible medicament and the vibrating gastrointestinal capsule. At least one of a time of ingesting of the vibrating gastrointestinal capsule and a timing or activation delay of the vibration mode of operation is controlled, such that the vibration mode of operation at least partially transpires or completely transpires within an actual or estimated absorption time period of the ingestible medicament within the gastrointestinal tract of the subject.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: January 28, 2020
    Assignee: Vibrant Ltd.
    Inventor: Lior Ben-Tsur