Abstract: An apparatus for use with an access port implanted in a living body includes a locator assembly. The locator assembly includes at least one port sensor configured to sense an aspect of the access port, at least one skin sensor configured to sense a proximity of the apparatus to a skin of the living body, and a controller configured to determine a location of the access port based on the aspect sensed by the at least one port sensor, where the controller instructs the at least one port sensor to sense the aspect based on the proximity of the apparatus to the skin as sensed by the at least one skin sensor. The locator assembly also includes an output device configured to provide user feedback, and the controller is further configured to instruct the output device to provide the feedback based on the determined location of the access port.

Abstract: An apparatus for use with an access port implanted subcutaneously in a living body includes a locator assembly and a base plate. The locator assembly includes a port sensor configured to sense an aspect of the access port, a controller configured to determine a location of the access port based on the aspect, and an output device configured to provide user feedback based on the determined location of the access port. The locator assembly also includes an outer housing having a device side coupler. The apparatus furthermore includes a base plate having an adhesive flange configured to adhere the base plate to a skin of the living body, and a base coupler on the adhesive flange and configured to cooperate with the device side coupler such that the base plate is attachable and detachable from the locator assembly.

Abstract: A method for administering at least one drug to a patient includes determining, with a locator assembly of an apparatus, a location of an access port under a skin of the patient. The method further includes adhering a base plate of the apparatus to the skin of the patient at a location corresponding to the location of the access port, detaching the locator assembly from a base coupler of the base plate adhered to the skin, and administering, through an opening in the base plate adhered to the skin, a first drug to the patient.

Abstract: A pump includes a conduit defining an inner volume and formed from a flexible material, the conduit movable between an expanded state and a relaxed state. A coil is disposed within the conduit and includes an outer diameter that is approximately equal to an inner diameter of the conduit, the coil substantially maintaining its outer diameter when the conduit is moved between the relaxed state and the expanded state. A manifold is in fluid communication with the inner volume and is operable to permit fluid to enter the inner volume in a first mode and expel fluid from the inner volume in a second mode.

Abstract: A fluid drainage device which includes a fluid-receiving volume, a cover which is movable between a first limiting position at which an inlet port is in fluid communication with the volume and a second limiting position at which an outlet port is in fluid communication with the volume, a piston which is movable inside the volume between a first position and a second position, a handle which is moveable in a first direction to cause the piston to move to the first position and to store energy in a spring so that, when the cover is in the first limiting position the piston is moveable by energy released from the spring to reduce pressure in the volume, allowing fluid flow through the inlet port, and wherein movement of the handle in a second direction causes the piston to move to the second position thereby expelling fluid from the volume.

Abstract: A needle hub for a drug delivery device includes a needle holder and a needle attached to the needle holder, a needle actuation assembly configured to move the needle holder from a retracted position, to an insertion position, and back to the retracted position, and a pressure interlock comprising an inlet configured to be in fluid communication with a fluid source, an outlet in fluid communication with the needle, and a lock member. The lock member having a first position where the lock member prevents actuation of the needle actuation assembly and a second position where the lock member allows actuation of the needle actuation assembly. The lock member is moved from the first position to the second position based on a pressure within the pressure interlock.

Abstract: An apparatus for injectate delivery includes a cartridge, a linear actuator, a rotary motor mechanically coupled the actuator, and a controller coupled to the motor. The controller controls a linear motion of the actuator by controlling an electrical input supplied to the motor in a first interval during which the motor is stationary with the linear actuator engaged with the cartridge to displace an injectate in the cartridge, a second interval following the first interval during which the controller accelerates the motor from stationary to a first speed selected to create a jet of the injectate from the cartridge with a velocity sufficient to pierce human tissue to a subcutaneous depth, a third interval during which the controller maintains the motor at or above the first speed, and a fourth interval during which the controller decelerates the motor to a second speed to deliver the injectate at the subcutaneous depth.

Abstract: An infusion device (1) for administering a medical fluid to a patient (P) comprises a pumping mechanism (4) configured to act onto a fluid conduit (20), the pumping mechanism (4) comprising a pumping section (42) movable with respect to said fluid conduit (20) for causing a fluid flow (F) through said fluid conduit (20). The pumping mechanism (4) comprises a multiplicity of rotatable gear elements (45A-45E) coupled to the pumping section (42) at a multiplicity of different locations (43A-43E), wherein the gear elements (45A, 45E) are operatively coupled to each other for a coordinated rotation of the gear elements (45A-45E) for moving the pumping section (42). In this way an infusion device is provided which may allow for a small-sized pumping mechanism, yet providing for a reliable and efficient infusion operation.

Abstract: An apparatus for use in injectate delivery includes an actuator including a linkage, a force generating mechanism mechanically coupled to the linkage, and a controller coupled to the force generating mechanism. The force generating mechanism includes a passive force generator and an active force generator. In operation and on the basis of a control signal, the controller is configured to control the force generating mechanism to provide an input force to the linkage that is a combination of the first force provided by the passive force generator and a second force provided by the active force generator.

Abstract: A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor device 100 comprises an in vivo portion 160 configured for insertion under the skin 180 of the host and an ex vivo portion 170 configured to remain above the surface of the skin 180 of the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing element 110 configured for piercing the skin 180 of the host and a sensor body 120 comprising a material or support member 130 that provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portion 170 may be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit 150. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.

Abstract: A drug self-delivery device comprising a body portion containing a drug vial and a needle assembly, where the body portion is slidably engaged to a trigger portion. When engaged by a user pressing the trigger portion against the user's flesh, the needle assembly relative to the drug vial so as to align a needle port with an integral drug delivery port connected to the drug vial thereby allowing fluid flow of medication through the needle. Seals engaged by a penetration spring prevent loss of medication and prevent the need for direct connection between the needle assembly and the drug vial.

Abstract: A device for dispensing a controlled amount of a fluid from a syringe, the syringe having a plunger extending along a linear axis through a syringe flange and into a syringe barrel. The device includes a housing to accommodate at least a portion of the syringe, and a drive wheel attached to the housing to contact a side of the plunger, the housing to press the drive wheel into the side of the plunger between the syringe flange and an end of the plunger.

Abstract: The present it relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used aspsposables, thereby allowing accurate and safe use and convenient maintenance.

Abstract: A feeding device according to the present invention includes a tubular body which has an a female screw portion, a movable shaft which has a male screw portion and is movable between a start position and an end position according to a rotation of the tubular body, a final gear which is provided in the tubular body, a drive unit which has the driving gear, a power transmission mechanism which transmits a driving force from the driving gear to the final gear via a plurality of intermediate gears, and a biasing mechanism which is configured to apply a biasing force to the movable shaft. At least one of the plurality of intermediate gears is a two-stage gear. The biasing mechanism is configured to apply the biasing force from the end position toward the start position and presses the male screw portion against the female screw portion to the start position side.

Abstract: An injection device for delivering a dose of medicament from a syringe (5), the injection device comprising a housing (10), a plunger (210) moveably mounted within the housing (10), an actuation mechanism (200), a trigger mechanism (40), and a plunger velocity regulator. The actuation (mechanism (100) is arranged to provide a forward biasing force to urge the plunger (210) forward in use to express a dose of medicament, and the trigger mechanism (40) is arranged to releasably hold the plunger (210) against the force of the actuation mechanism (200). The plunger velocity regulator comprises a cam surface (262) associated with the housing, and a cam member (252) associated with the plunger (210) and arranged to engage the cam surface (262) during actuation movement of the plunger (210) such that axial movement of the plunger (210) relative to the housing (10) causes relative rotational movement of the cam member (252) which limits the forward velocity of the plunger movement.

Abstract: An administration assembly is presented having a plunger rod, a first resilient member biasing the plunger rod, an elongated plunger rod holder configured to receive the plunger rod, an activation sleeve receiving a portion of the plunger rod holder, and configured to move axially from a first position relative to the plunger rod holder to a second position. The activation sleeve is biased towards the first position and the plunger rod holder has a first and second hold and release structure, wherein in the first position the activation sleeve is configured to maintain the first hold and release structure in an axially locking contact position with the second hold and release structure in which the second hold and release structure is prevented from movement relative to the first hold and release structure, thereby locking the plunger rod axially relative to the plunger rod holder.

Abstract: A device for infusion of medical fluids is provided. It has an internal reservoir for a fluid to be administered made of a first flexible base material to vary its volume as a function of the quantity of fluid present thereinside; and an outer casing containing the reservoir, having a side wall made of a second elastic base material suitable to make elastically deformable the casing to vary the geometry and internal volume thereof as a function of the volume of the reservoir.

Abstract: An injection device comprising a cap for removing a needle protection cap from a product container, and a method for assembling an injection device. The cap comprises an engaging element for removing the needle protection cap from the product container when the cap is removed from the injection device. The engaging element can be deformed in such a way that the engaging element can be moved from a distanced position, in which the engaging element is radially distanced from the needle protection cap, into an engagement position, in which the engaging element engages with the needle protection cap, with the engaging element being deformed when the cap is removed.

Abstract: The present disclosure relates to a medicament delivery device. The medicament delivery device includes a needle for delivering a medicament and an insertion mechanism configured to urge the needle in a first direction parallel to a longitudinal axis of the needle. The insertion mechanism includes a driving mechanism and a cam. The driving mechanism is configured to exert a force in a second direction perpendicular to the first direction. The cam is coupled to the needle and is configured to receive a force from the driving mechanism and move in the first direction in response to the received force.

Abstract: A medical pump, comprising: a fluid housing having a plurality of intake openings, sealed by at least one intake valve, and an outlet opening sealed by an outlet valve; a piston which is sealing the fluid housing and connected to a drive mechanism, the drive mechanism pulls the piston to draw fluid from one of the plurality of intake openings and pushes the piston to discharge the fluid into the outlet opening; and a selecting valve enclosing at least two tubes, each providing fluid to one of the plurality of intake openings, wherein the selecting valve closes one of the at least two tubes while opening another of the at least two tubes.

Abstract: The invention concerns a device (1) for measuring a fill level of a flexible medicine reservoir (6). The device (1) comprises a support (2) for supporting the flexible medicine reservoir (6) and a leaf spring member (3). A first section (31) of the leaf spring member (3) is mounted to a fixed bearing. A second section (32) of the leaf spring member (3) is guided by a floating bearing. The leaf spring member (3) is designed for contacting the flexible medicine reservoir (6) and for providing that changes in the fill level of the flexible medicine reservoir (6) effect changes of the form of the leaf spring member (3). A detector (5) is arranged for detecting the effected changes of the form of the leaf spring member (3) and for enabling measuring of the fill level of the flexible medicine reservoir (6).

Abstract: A medical liquid administration device includes a flowing portion including a flow path through which a medical liquid is to flow; a medical liquid storage communicating with the flowing portion, the medical liquid storage storing the medical liquid that is to be fed to the flowing portion; a drive mechanism comprising a motor configured to generate a driving force for feeding the medical liquid stored in the medical liquid storage to the flow path; a detection unit configured to detect whether an operating state of the drive mechanism is within a preset range; and a controller configured to determine a blockage in the flowing portion and a failure in the drive mechanism.

Abstract: The present disclosure relates to a medicament delivery device including a cartridge holder to which an injection needle holder can be fixed, the injection needle holder holding an injection needle having a proximal end and a distal end, the proximal end being protected by an inner injection needle cap detachably connected to the injection needle holder, the cartridge holder being mounted in a housing and configured to receive a cartridge of medicament, a cap assembly detachably connected to the housing, and a gripping mechanism configured to remove the inner injection needle cap from the injection needle holder when the cap assembly is pulled away from the cartridge holder.

Abstract: A medication injection device comprising a medication container to contain medication; a connector provided with a blocking feature; a push rod having a plurality of teeth disposed along the length, and a spring biasing against the push rod to move proximally. The spring can be compression spring, extension spring, torsion spring, or constant force spring. By enabling or disabling engagement between the blocking feature on the connector and the tooth on the push rod, the push rod is either prevented from moving distally or allowed to move distally. The medication is drawn into the medication container when the push rod moves proximally and the medication is dispensed out of the medication container when the push rod moves distally.

Abstract: A device for drainage includes a tubular reservoir having a tubular pliable wall, a rigid cover, and a rigid bottom, and also includes at least one spring which applies a force that presses the cover and the bottom apart, wherein the cover is movable in the direction of the bottom in order to place the spring into a start position. One or more magnets are configured such that the magnets apply an additional force on the reservoir in such a way that a resulting force pressing the cover and the bottom apart is substantially constant across as the spring is deflected.

Abstract: A method of providing and/or injecting octreotide acetate to a subject in need thereof includes storing the octreotide acetate in a cartridge of a multi-use multi-dose injector provided with a variable dose setter and actuator. The injector includes a needle configured for subcutaneous administration of the octreotide acetate, the octreotide acetate having a concentration of 2,500 ?g/mL. The method further includes providing, on the injector, a plurality of indicia only at prescribed doses of 50 ?g, 100 ?g, 150 ?g and 200 ?g settable via the dose setter without indicia between said prescribed doses; and permitting setting of a dose of the octreotide acetate by rotation of the variable dose setter, wherein the injector is configured to provide at least one audible feedback during the rotation.

Abstract: An injector apparatus includes a housing (101, 102) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to the plunger (40), and the dose setting arrangement includes a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring.

Abstract: Disclosed herein are devices and methods for reduced pressure tissue therapy. Some variations of suction devices for reduced pressure tissue therapy comprise a housing, a suction force generating mechanism located within the housing, and a storage module configured to retain tissue exudates. In some variations, the storage module includes a sleeve configured to collect tissue exudates. The sleeve may include a support element to help maintain the lateral structural integrity of the sleeve and/or retain the cross-sectional geometry of the sleeve under negative pressure. In use, the storage module may reduce sanitary and/or biohazard risks by preventing the exudates from contacting the housing and/or suction force generating mechanism. The storage module is configured to be replaced so that the housing and suction force generating mechanism can be used for more than one session.

Abstract: A caulk dispensing assembly is configured to dispense caulk in a consistent manner. The caulk dispensing assembly has a bottom plate with a pair of bottom plate rails and bottom plate slot with a bottom plate slot tab. A caulk tube has a caulk tube tip and a caulk tube hanging tab. The caulk tube hanging tab is arranged around the bottom plate slot tab. A top plate is arranged between the pair of bottom plate rails. Sliding the top plate between the pair of bottom plate rails compresses the caulk tube causing caulk to be dispensed from the caulk tube tip in a consistent manner.

Abstract: A method for treating tissue of at least one of an internal carotid artery, an ophthalmic artery, or an ostium between the internal carotid artery and the ophthalmic artery of a subject may include expanding a first expandable device of a first device in the internal carotid artery. The method also may include delivering a second device in the ophthalmic artery via the first device and expanding a second expandable device of the second device in the ophthalmic artery. Further, the method may include adjusting a radial position of the second expandable device relative to the first expandable device.

Abstract: An apparatus for injectate delivery includes a cartridge, a linear actuator, a rotary motor mechanically coupled the actuator, and a controller coupled to the motor. The controller controls a linear motion of the actuator by controlling an electrical input supplied to the motor in a first interval during which the motor is stationary with the linear actuator engaged with the cartridge to displace an injectate in the cartridge, a second interval following the first interval during which the controller accelerates the motor from stationary to a first speed selected to create a jet of the injectate from the cartridge with a velocity sufficient to pierce human tissue to a subcutaneous depth, a third interval during which the controller maintains the motor at or above the first speed, and a fourth interval during which the controller decelerates the motor to a second speed to deliver the injectate at the subcutaneous depth.

Abstract: An apparatus for injectate delivery includes a cartridge, a linear actuator, a rotary motor mechanically coupled the actuator, and a controller coupled to the motor. The controller controls a linear motion of the actuator by controlling an electrical input supplied to the motor in a first interval during which the motor is stationary with the linear actuator engaged with the cartridge to displace an injectate in the cartridge, a second interval following the first interval during which the controller accelerates the motor from stationary to a first speed selected to create a jet of the injectate from the cartridge with a velocity sufficient to pierce human tissue to a subcutaneous depth, a third interval during which the controller maintains the motor at or above the first speed, and a fourth interval during which the controller decelerates the motor to a second speed to deliver the injectate at the subcutaneous depth.

Abstract: The invention relates to an insertion device comprising—a penetrating member (50) connected to transformation means (52), —a moving part (38) comprising guiding means (39) which guiding means (39) restrict the movement of the transformation means (52) and guide the penetrating member (50) from a first to a second position in a first direction, i.e. the direction of insertion, towards the injection site, and—a stationary housing (30) comprising guiding means (32) which guiding means (32) restrict the movement of the moving part (38). The guiding means (32) guide the moving part (38) in a second direction which is linear and different from the first direction i.e. the direction of insertion.

Abstract: A multi-stage drug delivery system having a cartridge and multiple plungers positioned in the cartridge and spaced apart from one another is provided. A first plunger, a second plunger, and the cartridge form a first chamber storing a first drug. The second plunger and the cartridge form a second chamber storing a second drug. A cannula pierces the first plunger to access the first drug. As the first plunger is driven toward the second plunger, the first drug is expelled from the first chamber for delivery to a patient through the cannula. After expelling the first liquid drug, the cannula can pierce the second plunger to access the second drug. As the first and second plungers are together driven toward a closed end of the cartridge, the second liquid drug is expelled from the second chamber for delivery to the patient through the cannula.

Abstract: A supplemental device for attachment to an injection device, the supplemental device comprising: an electromechanical switch arrangement having an open state and a closed state, the electromechanical switch arrangement comprising a protrusion configured to contact a surface of the injection device when a dose of zero units is dialled into the injection device, wherein the state of the switch arrangement is configured to change when a dose dialled into the attached injection device is decreased from one unit to zero units; and a processor arrangement configured to: detect one or more changes in the state of the electromechanical switch arrangement; and determine from the one or more state changes that a dose of zero units is dialled into the injection device.

Abstract: Described is a medicament cartridge comprising a housing having open proximal and distal ends, a first coupling mechanism, and a syringe slidably disposed in the housing. The syringe includes a needle and has a retracted position in which the needle is covered by the housing and an extended position in which the needle is exposed. A delivery device comprises the medicament cartridge, an actuator comprising a plunger, a motor adapted to translate the plunger, a second coupling mechanism adapted to detachably engage the first coupling mechanism, and a control button adapted to actuate the motor. A carrier comprises a first slot for at least partially containing the actuator, a second slot for at least partially containing the medicament cartridge, a user interface adapted to provide at least one a visual signal and an audible signal.

Abstract: Disclosed herein are improved devices, systems, and methods for the expression and collection of breast milk, such as human breast milk. A breast shield assembly for expression of breast milk may comprise a breast interface and an actuatable assembly interface fluidly coupled with a tube, wherein the breast interface is configured to engage the breast and the actuatable assembly interface is configured to removably couple to an actuatable assembly. The breast shield assembly may comprise an enclosed fluid reservoir extending between the breast interface and the actuatable assembly interface, the fluid reservoir physically separated from the expressed breast milk and filled with a driving fluid comprising a liquid. The breast shield assembly may further comprise a fill port configured to allow addition or removal of the driving fluid to or from the fluid reservoir.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery.

Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

Abstract: A medical injection device, comprising: a housing having a first end cover and a second end cover provided at two ends thereof, respectively; a dial threaded rod, which is in threaded connected to the first end cover; and, a piston rod, which is used for expelling a dose, an upper end of the piston rod being connected to the dial threaded rod through a driving mechanism while a lower end thereof is in threaded connected to the second end cover. It further comprises a dosage adjustment mechanism, which is arranged between the dial threaded rod and the housing and used for driving the dial threaded rod to move in an axial direction of the housing.

Abstract: An injection device includes a housing for receiving a syringe or cartridge for containing a medicament; a rotary driveshaft mounted for rotation relative to the housing; and an elongate coiled torsion spring having respective formations at opposite ends thereof, with a first formation being anchored in a seat on the rotary drive shaft and a second formation being anchored in a seat on a reaction component. In use relative rotation of the rotary driveshaft and the reaction component in one angular direction strains the torsion drive spring, and release of the strained torsion drive spring causes expression of medicament from the syringe or cartridge. The torsion spring is longitudinally resiliently compressible between its end formations whereby during assembly of the injection device, the torsion spring may be longitudinally compressed and then rotated, thereby urging the end formations of the torsion drive spring into engagement with the respective seats.

Abstract: Aspects of the disclosure are directed to a borescope grip defined about a central longitudinal axis, comprising: a reaction case that includes a first flange having a first face that is substantially perpendicular to a central longitudinal axis of the grip, an o-ring that abuts the first face of the first flange, a plunger that includes a second flange having a second face that abuts the o-ring at a first axial position and is disengaged from the o-ring at a second axial position, and a spring that abuts the second flange.

Abstract: A medical injection device used to deliver multiple doses of medication, including: a medication container having a movable piston; a push rod assembly having a plurality of spaced-apart position settings disposed along the length, the push rod assembly displacing the movable piston to dispense medication from the medication container; a spring to bias the push rod assembly to move toward the distal end of the medical injection device; a releasable restraining member configured to restrain the push rod assembly in a locked state against the biasing of the spring, upon release of the releasable restraining member, the push rod assembly moves toward the distal end of the medical injection device; and an arming mechanism configured to move the push rod assembly toward the proximal end of the medical injection device.

Abstract: An injection device includes a housing having a receptacle for a vessel for holding injection fluid; an operator-manipulated element for setting an injection dose; a dosing member rotatable about a longitudinal center axis relative to the housing when setting the injection dose; a feed part; and, a latching unit acting between the feed part and housing. The dosing member has a zero position whereat no dose is set and an injection position whereat an intended dose of injection fluid is set. A spring acts between the dosing member and the housing to return the dosing member from an intermediate position to the injection position or a zero position.

Abstract: A spring assisted drug delivery device is provided comprising a housing and a lead screw having a longitudinal axis, a distal end and a proximal end that is rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing. The device further comprises a drive nut threadedly engaged and screwable along the lead screw threaded shaft and a number sleeve threadedly engaged with the housing to be screwable relative to the housing. A dial link is connected with the drive nut and axially movable and rotatably fixed relative to the drive nut and an inner sleeve is threadedly engaged with the number sleeve, the inner sleeve being axially movable and rotatably fixed relative to the housing. A mid-body is axially fixed inside of the housing. A spring is provided that assists a user of the device during a dose administration step.

Abstract: Injection device comprising a tubular elongated main body, a needle shield slidably arranged in said main body, a needle shield link slidably connected to said needle shield, a enclosure containing medicament arranged in said main body, a needle connected to said enclosure, a plunger operatively arranged to said enclosure for ejecting said medicament through said needle and arranged on its upper part with a number of outwardly extending stop members, spring means arranged to said plunger for operating said plunger, a dose activating means, a needle shield spring surrounding the needle shield link.

Abstract: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing having a tubular portion with an inner thread, a piston rod having a threaded portion and a distal end, and a bearing having a distal face and a proximal face. The bearing includes a retaining stem protruding from the proximal face. The piston rod includes a distal portion having an outer diameter which is smaller than the inner diameter of the inner thread of the tubular portion and comprising at its distal end at least one retaining clip engaging the retaining stem. The axial length of the tubular portion is smaller than or equal to the axial distance between the proximal face of the bearing disc and the distal end of the threaded portion of the piston rod. During manufacturing of the device, the retaining clip engages the retaining stem prior to the inner thread of the tubular portion engages with the threaded portion of the piston rod.

Abstract: A dispensing device which disperses medicate through a needle across a zone within a body. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a reservoir in fluid communication with the needle, positioned within the housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with the reservoir-connecting conduit, and a linear drive attached to the needle or to the needle-receiving member. The fluid drive impel fluids from the second reservoir to the reservoir-connecting conduit and thus drives the therapeutic agent from the reservoir during the linear displacement of the needle towards the housing. Fluid communication from the therapeutic agent reservoir to the needle is maintained by the tubing during operation of the linear drive.

Abstract: Described is an auto-injector for administering a medicament comprising a case arranged to receive a packaged syringe comprising an injection needle, wherein the case comprises a front case rotatably coupled to a rear case, and a drive spring arranged to advance a plunger relative to the packaged syringe, and a reset mechanism for the drive spring arranged to retract the plunger and compress the drive spring when the front case is rotated relative to the rear case.

Abstract: The invention relates to an insertion device comprising —a penetrating member (50) connected to transformation means (52), —a moving part (38) comprising guiding means (39) which guiding means (39) restrict the movement of the transformation means (52) and guide the penetrating member (50) from a first to a second position in a first direction, i.e. the direction of insertion, towards the injection site, and —a stationary housing (30) comprising guiding means (32) which guiding means (32) restrict the movement of the moving part (38). The guiding means (32) guide the moving part (38) in a second direction which is linear and different from the first direction i.e. the direction of insertion.