Abstract: Adaptors, cannulas, caps, tube couplers, and systems thereof provide endovascular access through an established ECLS system. Adaptors having curved or angled shafts navigate right angle side ports of standard bypass cannulas and permit hemostatic introduction and direction of an intervention device to the axial flow path of the cannula lumen and bypass system. A modified cannula having an angled side port is also provided for use as an arterial cannula. A cap having an occluding surface may be inserted into the angled side port to prevent blood from stagnating in the angled side port. A tube coupler is also provided having an access port, such as an angled access port, and may be spliced into an established bypass system for vascular access point. Multiple couplers can be used to provide multiple access points. The adaptors and occlusive cap are interchangeable with each other and with secondary circuits.

Abstract: A system and method for enhanced navigation for use during a surgical procedure including planning a navigation path to a target using a first data set of computed tomography images previously acquired; navigating a marker placement device to the target using the navigation path; placing a plurality of markers in tissue proximate the target; acquiring a second data set of computed tomography images including the plurality of markers; planning a second navigation path to a second target using the second data set of computed tomography images; navigating a medical instrument to a second target; capturing fluoroscopic data of tissue proximate the target; and registering the fluoroscopic data to the second data set of computed tomography images based on marker position and orientation within the real-time fluoroscopic data and the second data set of computed tomography images.

Abstract: A system for enhanced surgical navigation including a computing device and an imaging device. The computing device is configured to import a navigation path to a target using a first data set of computed tomography images previously acquired, display the navigation path on a graphical user interface for navigation to the target and placement of a plurality of markers in tissue proximate the target, and acquire a second data set of computed tomography images including the plurality of markers. The imaging device is configured to capture fluoroscopic data of tissue proximate the plurality of markers. The computing device is further configured to register the fluoroscopic data to the second data set of computed tomography images based on marker position and marker orientation within the fluoroscopic data and marker position and orientation within the second data set of computed tomography images.

Abstract: A seal member and outer cylinder needle (OCN) tip part for blocking, in a fluid-tight state, both external peripheral space (EPS) end parts formed between the external-peripheral-surface of an inner needle (IN) and internal peripheral surface of an OCN, for slidably holding the IN in close contact; an opening part formed on the OCN external-peripheral-surface and for intravascular communication with the EPS; an OCN connection part for communicating between the EPS and blood circuit end; an IN connection part for communicating between the IN internal space and other blood circuit end. The movable IN positioned between the projecting position where the tip part protrudes from the OCN tip and the housed position housing the tip inside the OCN. The IN punctures the blood vessel interior while holding the projecting position, and moved to the housed position after puncture allowing blood to extracorporeally circulate via the OCN and IN connection part.

Abstract: Provided is an endoscopic surgical device and an overtube with which a surgeon can easily obtain a desired image and in which operability is high. The overtube includes a slider within an overtube body, which guides an endoscope and a treatment tool into a body cavity. An endoscope-coupled part and a treatment tool-coupled part are provided inside the slider, and the slider has a dead zone where the forward and backward movement of either the endoscope or the treatment tool does not interlock with the movement of the other and a sensing zone where the forward and backward movement of either the endoscope or the treatment tool interlocks with the movement of the other. The overtube body is configured to allow the treatment tool to rotate around an axis thereof without changing the positional relationship of the endoscope and the treatment tool with respect to the overtube body.

Abstract: An introducer having a dilator positioned in a sheath is inserted into a first blood vessel and, thereafter, only the dilator tube is drawn out of the first blood vessel and the sheath while the sheath remains in the first blood vessel. A diagnostic instrument having an outer diameter smaller than a maximum outer diameter permitting insertion into the sheath tube is inserted into the second blood vessel, and a stenosis of the second blood vessel is diagnosed. While keeping the sheath indwelling in the first blood vessel, a therapeutic instrument or a catheter permitting the therapeutic instrument to be inserted therein, which therapeutic instrument or catheter has a maximum outer diameter permitting insertion into the sheath tube, is inserted into the second blood vessel, and the second blood vessel is treated.

Abstract: An indwelling assembly includes an inner needle having a sharp needlepoint, an inner needle hub fixed to the inner needle, a hollow elongated outer member in which the inner needle is positioned and movable in a distal direction relative to the inner needle after puncturing the blood vessel to position the elongated outer member at a desired position in the blood vessel, an outer member hub fixed to hollow elongated outer member, a projection removably connected to the outer member hub and configured to be engaged by a finger of the user to apply a force to the projection causing the outer member hub and the hollow elongated outer member to move together with the projection in the distal direction relative to the inner needle and the inner needle hub, and an elongated movable member that is movable relative to the hollow elongated outer member and the outer member hub.

Abstract: A needle system and methods for using the needle system are described. The needle system is generally intended for medical use and can be used when performing a dialysis on a patient, for example, hemodialysis. In general, the needle system can address problems that commonly arise when using conventional single or double needle systems during hemodialysis.

Abstract: Methods and devices are provided for transporting fluid between a body and an external source. More particularly, the methods and devices provided can be used to transport blood from a body. In one exemplary embodiment, a system is provided for transporting fluid between a body and an external source. The system can include a collection catheter that is sized to fit inside a catheter that is placed in the body and configured to have its distal end extend beyond a distal end of the catheter that is placed in the body. Various methods for transporting fluid from the body to an external source are also provided.

Abstract: A catheter-based/intravascular fluid injection system with application to renal denervation includes a multiplicity of needles which expand open around a central axis to engage the wall of a blood vessel, or the wall of the left atrium, allowing the injection of a cytotoxic and/or neurotoxic solution for ablating conducting tissue, or nerve fibers around the ostium of the pulmonary vein, or circumferentially in or just beyond the outer layer of the renal artery. The expandable delivery system includes expandable components that facilitate positioning of a multiplicity of injection needles against the inside wall of a blood vessel from where they can be advanced. The system also includes means to limit and/or adjust the depth of penetration of the ablative fluid into the tissue of the wall of the targeted blood vessel.

Abstract: A needle structure for injecting a filler and monitoring a blood backflow situation simultaneously includes a needle, a housing and a partitioning member. The needle includes a needle chamber and a needle opening connected to the needle chamber. The housing includes a housing chamber and a housing opening connected to the housing chamber, and the housing chamber is connected to the needle chamber to form a needle housing chamber. The partitioning member is disposed in the needle housing chamber. The needle housing chamber is separated into a first chamber and a second chamber by the partitioning member. The needle opening is separated into an injection opening and a blood backflow opening by the partitioning member. The first chamber is connected to the injection opening, and the blood backflow opening and the housing opening are connected by the second chamber.

Abstract: An infusion set adapted to be secured to a skin surface includes a fixed base member and a movable slide member. The fixed base member is connectable to the skin surface. The movable slide member has a needle or cannula connected thereto and is movable relative to the fixed base member. The movable slide member is movable from a first position in which the needle or cannula is not exposed externally of the fixed base member to a second position in which the needle or cannula is exposed externally of the fixed base member. A hub is fixedly connected to the movable member and has a slot extending rearwardly in a lower surface from a first end thereof. The needle or cannula is received in the slot. The movable slide member is locked to the fixed base member in the second position.

Abstract: A catheter assembly includes a catheter hub defining an interior cavity and a catheter tube extending distally thereof. A rigid actuator is positioned to extend proximally in the interior cavity and support a seal member positioned thereon in the interior cavity. The seal member includes a central membrane, a distal portion, and a proximal portion. An hourglass shaped actuator cavity is formed in the distal portion and receives a barbed end of the actuator. The outer surface of the seal member is in partial circumferential engagement with the catheter hub to define an air path that allows fluid communication between areas of the interior cavity distal and proximal of the seal member. The seal member may be configured for multi-use and include a biasing member that moves the seal member to force the membrane back over the actuator to close the membrane.

Abstract: The disclosure provides apparatus and methods for reentering a true lumen. The reentry catheter includes a shaft that includes a proximal opening in a proximal end of the shaft, a J-shaped filler in a distal end of the shaft, and a distal side opening in a sidewall of the shaft. The distal side opening is adjacent to the J-shaped filler. A passageway extends between the proximal opening and the distal side opening. The proximal opening, the distal side opening, and the passageway each are configured for the passage of an elongate medical device there through. A movable cover is hingedly attached to the sidewall of the shaft biased in a closed position and configured to occlude the distal side opening when in the closed position. The elongate medical device is configured to open the movable cover, the movable cover is configured to facilitate reentry to a true lumen.

Abstract: An apparatus for remotely and subcutaneously positioning a tethering strand in tissue includes a housing, an actuator coupled with the housing for longitudinal reciprocation relative to the housing, and a nested pair of needles including a first needle coupled with the housing and a second needle coupled with the actuator. One of the needles has a sharpened tip and another one of the needles has a blunted tip. The first needle has a first length and the second needle has a second length, and the first length and the second length are selected so that advancement of the second needle using the actuator causes the sharpened tip to project beyond the blunted tip, and so that retraction of the second needle using the actuator causes the blunted tip to project beyond the sharpened tip.

Abstract: Disclosed herein are devices and methods for assessing the surface of a target cardiac tissue and for delivering a tissue anchor to cardiac tissue at a preselected depth within the myocardium in a beating heart procedure. In one variation, an anchor delivery device comprises an elongate body, a tissue anchor disposed within a first longitudinal lumen of the elongate body, and a tissue depth indicator slidable within a second longitudinal lumen of the elongate body. The tissue depth indicator has a first configuration that indicates the boundary of the surface of the target tissue and a second configuration that indicates when the distal tip of the elongate body has been advanced to a preselected depth into the target tissue. In some variations, a tissue depth indicator may also be configured to resist or limit the penetration of the delivery device into tissue after a preselected depth has been reached.

Abstract: The invention relates to a hollow needle (1) for a sample pipettor in an automated analysis instrument, which sample pipettor is suitable for withdrawing sample liquid from a sealed sample vessel by virtue of the cover or the cap of the sample vessel being pierced by the hollow needle (1). The hollow needle (1) has a substantially straight cylindrical basic shape with a tip (8) for piercing a cover and enables a removal of sample liquid, comparatively less susceptible to errors, from a sample vessel in an automated analysis instrument. In the region of the tip (8) of the hollow needle (1), a number of faces (22, 26, 28, 30) have been introduced in such a way that the radial force components resulting at the respective faces (22, 26, 28, 30) during an axial movement into an elastic material cancel one another.

Abstract: A seal assembly including a septum seal, a lower seal support, an upper seal support and a return spring is disclosed. The septum seal includes an orifice and a plurality of apertures. The lower seal support includes an engagement surface configured to engage a portion of the septum seal. The upper seal support includes a plurality of fingers, wherein each of the plurality of fingers is configured to extend through a corresponding aperture of the septum seal. The return spring includes a collar portion and a plurality of spokes extending radially outward from the collar portion. At least a portion of the return spring may be sandwiched between the lower seal support and the upper seal support. The plurality of spokes is configured to bias the seal assembly toward a radial center of a housing.

Abstract: The application discloses a set of surgical instruments that may be used to access a human or animal body cavity for medical purposes without causing damage to internal tissues or organs therein, and methods of using the same. The instruments include a safety needle and flexible sheath that may be coupled together and used to establish a minimally invasive method to access a targeted body cavity while preventing or reducing damage to organs or tissues within the targeted cavity. Additional instruments are included within the invention that may be used to establish an access port in the wall of the targeted cavity. That port may be used to introduce catheters or other instruments into the body cavity. It may also be used as a drainage tube for draining or injecting gases and/or fluids from or into the targeted cavity.

Abstract: An apparatus for delivering devices. The apparatus comprises a catheter with an elongated shaft having a first lumen and a second lumen extending therethrough. The apparatus further comprises a distal section with a lumen in communication with a port in a distal end of the catheter and with the first lumen and the second lumen. The first lumen is configured for a first device and the second lumen is configured for a second device to be disposed therein. The apparatus further comprises a proximal adapter coupled to the elongated shaft with a first port in communication with the first lumen and a second port in communication with the second lumen.

Abstract: The invention is a skin puncturing apparatus for use in a non-surgical method for eradication of a tattoo from an area of skin. The apparatus comprises: (a) a handle section comprising a motor and gear assembly for causing a reciprocating motion to a shaft connected to the gear assembly; (b) a barrel section surrounding the shaft, the first end of the barrel section attached to the handle and the second end of the barrel section having a tip adapted to be placed in contact with the area of skin; (c) a bundle of needles attached by means of a needles holder to the distal end of the shaft; and (d) an inlet body comprising an inlet port through which cleaning solution is introduced into the tip located at the lower edge of the barrel section.

Abstract: Devices, kits, assemblies systems and methods for transferring fluid to or from a subject include an elongate guide cannula having opposing proximal and distal ends with an open axially extending lumen. The proximal end includes a connector. The devices also include an elongate needle having opposing proximal and distal ends, the needle having a connector that is configured to attach to the guide cannula connector and is attached to or attachable to a length of flexible tubing, wherein the elongate needle is configured to be slidably inserted into the guide cannula lumen so that the distal end of the needle extends out of the distal end of the distal end of the guide cannula a suitable distance.

Abstract: In accordance with aspects of the present invention, a door mechanism is provided. A door mechanism according to some embodiments of the present invention includes a door that includes a sealing part, an arm connected to the sealing part, and a pivot part connected to the arm, the door rotating around a pivot axis at the pivot part; and a lever, the lever engaging the door at the pivot part such that the lever opens the door when engaged but is not affected when the door is opened without the lever.

Abstract: An infusion set has a partially integrated ballistic inserter that can insert a needle at a controlled rate of speed to a depth to deliver content to the upper 3 mm of skin surface, and a skin-securing adhesive layer to secure the skin surface at the insertion site such that the inserter that can insert a needle with a reduced risk of tenting of the skin surface. A removable turnkey or pushable handle can be provided to release a driving spring of the ballistic inserter to insert a needle at a controlled rate of speed, of 3.3 ft/sec. (1.0 m/sec.) up to and including those greater than 10 ft/sec. (3.0 m/sec.), then release from the set for disposal. The infusion set can further include an extendable interface ring that retracts when the inserter is removed from the infusion set.

Abstract: Sensors are disclosed that detect whether a cannula is properly inserted to its full depth in a subject's skin. The sensors may be used with a blood glucose monitor, or with a continuous insulin infusion pump, infusion set, or other system involving intermittent or continuous testing and/or drug delivery.

Abstract: A closed IV catheter system, includes a needle shield assembly positioned proximally of a catheter hub and distally of the needle hub. The needle shield assembly cooperates with the catheter hub on the outer circumferential and peripheral surface of the catheter hub. The needle shield adds additional length and width to the closed IV catheter system. An improved manufacturing process with unique materials is also presented.

Abstract: The present application pertains generally to medical systems and methods for creation of an autologous tissue valves within a mammalian body. In some embodiments, a system for creating an endoluminal valve from a blood vessel wall is provided. The system includes a tubular assembly having a longitudinal axis, a proximal end, a distal portion with a distal end, and a first lumen extending from the proximal end to a distal port located proximate the distal portion. The distal portion can have a supporting surface that extends in a longitudinal direction and is offset from a surface of the tubular assembly proximal the distal port. The system can further include a tissue dissection probe disposed within the first lumen.

Abstract: A surgical access device including a housing having a nozzle assembly, a gas supply plenum, a gas return plenum, and a pressure sensing plenum, as well as an elongated tubular body that extends from the housing portion and defines a central lumen communicating with the nozzle assembly and the gas return plenum, a telescopic cannula assembly associated with the tubular body and including a proximal section arranged coaxially within the tubular body and a distal section coaxially supported within the proximal section and mounted for movement relative to the proximal section between retracted and extended positions, and an elastomeric sheath associated with the telescopic cannula assembly and having a distal anchor portion for securing the surgical access device during a laparoscopic surgical procedure.

Abstract: An infusion set system, including a base and a fluid connector removably coupleable thereto is disclosed. The fluid connector includes a fluid path portion and at least one connector latch displaceably connected to the fluid path portion and displaceable to a latching position in which at least a portion of the connector latch extends into the fluid path portion, which includes a cannula extending from a top interior surface thereof, and a plurality of internal sidewalls corresponding to at least two of a plurality of flat side surfaces of at least one of a base section and a base latch, thereby facilitating connection between the base and the fluid connector in a plurality of discrete rotational connecting positions. When the fluid connector is locked to the base, the at least one connector latch engages a base latching portion of the base and restricts proximal displacement of the fluid connector.

Abstract: To provide a puncture device which prevents components constituting a puncture device from being damaged by buckling (bending) etc., secures safety, and can be handled by a weak user easily. A puncture device is provided with an outer needle, an outer needle hub for retaining a base portion of the outer needle, an inner needle whose tip portion is inserted in the outer needle, an inner needle hub for retaining a base portion of the inner needle, an outer pipe fitted inside the inner needle hub so as to be moveable to and fro, and an inner pipe having a gripping device for gripping the outer needle hub and fitted inside the outer pipe so as to be moveable to and fro, and at least the outer pipe is formed of a soft synthetic resin.

Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.

Abstract: An arrangement for introducing a liquid into the body of a patient or for withdrawing a liquid from the body of a patient, including a first structural part carrying a cannula for positioning in the body of the patient, and a second structural part with a connection port for detachably coupling a conduit for supplying or withdrawing a liquid, wherein the first and second structural parts are connected, can be rotated relative to each another and in relative rotational positions form a channel for introducing a liquid from the conduit to the cannula or for withdrawing a liquid from the cannula to the conduit, and whereby movement of the conduit for coupling and uncoupling is transverse to the longitudinal axis of the cannula.

Abstract: A puncture treatment tool includes a needle tube whose distal end is insertable into tissue, a cylindrical main body through which the needle tube is inserted, a needle stopper through which the main body is inserted and which is provided such that a position where the needle stopper is fixed to the main body can be changed in a direction of a longitudinal axis of the main body, and a slider which is fixed to a proximal end part of the needle tube, the slider being disposed to be operated movable relative to the main body. The slider is configured to be capable of selecting from a first state in which the slider is movable in the axial direction relatively to the main body without rotating in the circumferential direction of the main body, or a second state in which the slider is rotatable in the circumferential direction.

Abstract: A valved connector configured to control the leakage of bodily fluid from within a patient. The valved connector including a seal positioned within a lumen of the body of the valved connector. The distal end of the valved connector is adapted to permit access to, or coupling of an apparatus. A proximal end is adapted to be threadably coupled to a secondary device. The needless connector valve being configured to be openable by a dilator or post of an apparatus which is connected to the proximal end of the needleless connector. In the event that a luer coupler or other secondary apparatus is not available, a needle, cannula, trocar, or other instrument can be threaded through the main lumen of the valved connector opening the valve and allowing the passage of fluid directly through the needle, trocar, cannula, or other instrument.

Abstract: A method for inserting at least a portion of a dilator and sheath assembly into a patient and for removing the dilator from the patient is disclosed. Initially, the dilator and sheath assembly is received. The dilator includes a radially enlarged dilator bump. At least the distal ends of the dilator and the sheath are inserted in an incision in the patient. A vector force is exerted to the dilator and sheath assembly to push the dilator and sheath assembly further within the patient. The dilator hub is decoupled from the sheath hub. The dilator is removed from the patient through the sheath, where the dilator bump radially stretches at least the circumferentially continuous sheath distal end during removal of the dilator from the patient.

Abstract: A surgical apparatus includes a cannula and a surgical instrument. The cannula includes a curved longitudinal axis along at least a portion of its length. The surgical instrument includes an elongated shaft having a distal end and a proximal end, and an end effector coupled to the distal end of the elongated shaft. At least a portion of the end effector is configured to contact an inner surface of the cannula during insertion of the surgical instrument into the curved cannula. A threshold galling stress between the portion of the end effector and an inner surface of the curved cannula is at least 10,000 pounds per square inch.

Abstract: One aspect provides a multiple access body uniport for performing single site surgery on a body that comprises a one-piece body anchor defined by a longitudinal length and an uppermost surface and a lowermost surface. The uniport includes at least two surgical instrument passageways located through the one-piece body anchor and terminate at an entrance aperture on the uppermost surface and at an exit aperture on the lowermost surface, and also includes at least a third surgical instrument passageway located through the one-piece body anchor and having an elongated access opening extending across a portion of the uppermost surface and having an exit aperture on the lowermost surface.

Abstract: An intravascular access system for facilitation of intraluminal medical procedures within the neurovasculature through an access sheath. The system includes an aspiration or support catheter having a flexible, distal luminal portion having an inner diameter defining a lumen extending between a proximal opening at a proximal end of the luminal portion and a distal opening at a distal end of the luminal portion. The catheter has a rigid spine coupled to at least the proximal end of the luminal portion and extending proximally therefrom. The system includes a dilator having a flexible, distal dilator portion sized to be received within the lumen of the luminal portion. Associated systems, devices, and methods of use are also described.

Abstract: A medical catheter includes a deflectable and compressible catheter shaft; a pull ring near a distal end of the catheter shaft; a distal tip that includes a tip element and a mounting shaft; and an attachment apparatus for securely attaching the distal tip to the catheter shaft, the attachment apparatus including a compression ring which compresses the catheter shaft and the mounting shaft together. The compression ring can be located around the catheter shaft to compress the catheter shaft against an outer surface of the mounting shaft, or within the catheter shaft to compress the catheter shaft outwardly against an inner surface of the mounting shaft. The catheter can be a non-irrigated ablation catheter, with the tip element being a tip electrode, and it can be an irrigated ablation catheter, with the distal tip including a fluid manifold.

Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.

Abstract: In accordance with aspects of the present invention, an instrument guide is provided. An instrument guide according to some embodiments of the present invention includes a channel portion, the channel portion including a plurality of channels through which surgical instruments can be inserted; a lower part mechanically fixed to the channel portion, the lower part including doors to seal each of the channels; an upper part, the upper part mechanically attached to the lower part and including a funnel for guiding the instruments into the plurality of channels; and one or more seals fixed between the upper part and the lower part, the seal(s) having openings corresponding to the channels and sealing against the doors when the doors are closed and sealing against surgical instruments when surgical instruments are inserted into the channels.

Abstract: An injection device for injecting a material into tissue may include a sheath having a distal end. The injection device may also include an injector having an outlet tube. The outlet tube may be received in the sheath, and may include a distal portion with a penetrating tip for penetrating the tissue. The sheath and the outlet tube may be slidable relative to each other, to extend a length of the distal portion from the distal end. The injection device may also include an adjuster operatively coupled to at least one of the sheath and the outlet tube. The adjuster may be configured to control relative movement between the sheath and the outlet tube for selectively adjusting the extended length.

Abstract: A cannulated medical instrument handle apparatus comprised of a handle housing component with a hollow handle insert channel and a removable tubular insert that fits within the handle insert channel. Tubular insert has a hexagonal segment adapted to fit within a recessed hexagonal aperture within the handle insert channel, thereby connecting the handle housing component and tubular insert. Tubular insert also has a tubular shaft segment and a lumen running through its center.

Abstract: An indwelling assembly includes an inner needle having a sharp needlepoint at a distal end to puncture a blood vessel of a patient, an inner needle hub fixed to the proximal portion of the inner needle, a hollow elongated outer member in which the inner needle is positioned, with the hollow elongated member being movable in a distal direction relative to the inner needle after puncturing the patient's blood vessel, an outer member hub fixed to the proximal portion of the hollow elongated outer member, an elongated contact member configured to contact an intermediate portion of the hollow elongated outer member, and an elongated movable member movable relative to the hollow elongated outer member and the outer member hub. The elongated movable member is connected to the inner needle hub so that the inner needle hub, the inner needle and the elongated movable member move together.

Abstract: Devices, kits, and methods of treatment are described. More particularly, methods of treating tissue of a passage wall defining a bodily passage, such as a sinus cavity, airway, or sinus passage are described. An exemplary method utilizes an elongate member having an elongate member proximal end, elongate member distal end, and an elongate member body that defines a curve.

Abstract: An embodiment in accordance with the present invention provides a scope lens cleaning system disposed within a trocar shaft to allow the surgeon to clean the scope lens without losing orientation of the operative field. The lens cleaning system is configured to remove solid debris, liquid, and condensation from the scope lens. The cleaning system includes a first cleaning component configured to remove the solid debris from the scope lens. A second cleaning component is configured to remove the liquid and condensation from the scope lens. A third cleaning component wicks the solid debris and liquid away from the cleaning components and the scope lens and allows it to fall out the end of the trocar shaft. The cleaning system minimizes distraction during the surgical procedure to improve efficiency and safety.

Abstract: Devices, methods, and assemblies for perfusion therapy including cerebral perfusion therapy such as those for use in the treatment of acute ischemic stroke. The treatment includes delivery of blood to or about the vicinity of a thrombus site.

Abstract: Described are implantable therapeutic devices, systems and methods to treat a patient. The device includes a hollow refillable housing for implantation within the posterior segment of an eye through a penetration in the sclera including a proximal retention structure protruding outward from a proximal end region of the housing, an access portion opening, and a penetrable barrier positioned at least in part within the access portion opening, the penetrable barrier configured to be repeatedly penetrated. A rigid porous structure is positioned within a region of the housing away from the access portion opening into a reservoir chamber extends along an axis between the penetrable barrier and the porous structure includes a volume sized to deliver therapeutic amounts of a therapeutic agent to the eye for an extended period of time. A cover is coupled to at least an upper surface of the proximal retention structure.

Abstract: A liquid transport device is attachable to a living body and transports a liquid to the living body. The liquid transport device includes a pump unit that includes a storage portion for storing the liquid and a pumping portion for transporting the liquid in the storage portion to the living body, and a seal portion that attaches the pump unit to the living body. A portion of a surface of the living body side of the pump unit is separated from an upper surface of the seal portion. In the liquid transport device, the pump unit is easily fixed to a flexible surface of the living body and a load on the living body is reduced while securing areas for the lower surface of the pump unit and the sealing surface of the seal portion.

Abstract: A surgical guide wire or K-wire and method of use are provided. The K-wire, or guide wire, has opposite end portions and a shank portion in between. One end portion has a deformable end portion that, once outside of a confining guide passage, can be deformed to present a projected forward facing area that is larger than the transverse cross section of the K-wire, or guide wire, while in the passage. The increased area will provide increased resistance to additional forward axial movement into the surgical site.