Abstract: The present invention relates to a self-retaining enema nozzle (1,1?,1?,1??) and an enema system (34) comprising said enema nozzle. The enema nozzle (1,1?,1?,1??) comprises a catheter (2) provided with a retention member (3) arranged for being placed in a compact form during insertion in a body cavity and for being placed in an expanded form for retaining the enema nozzle in said body cavity, and wherein the enema nozzle (1,1?,1?,1??) further comprises a restriction unit (4) arranged for placing the retention member (3) in its compact form. Since the restriction unit (4) holds, e.g. keeps, places and/or maintains the retention member (3) in the compact form both before and during insertion, any discomfort and/or harm that may be experienced using the conventional enema nozzles/devices is effectively prevented.

Abstract: An embodiment of a uterine hemorrhage controlling system comprises a suction module including a suction end coupleable to a pump by a connecting tube, and a sealing module coupled to the suction module. The system may further comprise the pump and a filter coupled to the suction module. A uterine hemorrhage controlling method comprises: shielding a suction module that has been delivered into a uterus; sealing an entrance into the uterus while the suction module is situated within the uterus; applying a negative pressure within the uterus upon activation of a pump; and maintaining the negative pressure within the uterus to induce uterine contraction. The method may further comprise delivering the suction module into the uterus; transmitting bodily fluids, out of the uterus through the suction module, and filtering the bodily fluids.

Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).

Abstract: Formulations and methods of manufacture are provided for granisetron dry powder compositions suitable for intranasal administration. Also provided are methods of use for preventing or controlling emesis and other diseases and disorders and devices, compositions, and methods for nasal delivery of therapeutic formulations. Devices for delivery of dry powder formulations are also provided. Devices can be single-use devices.

Abstract: Systems and methods for infusion of fluids using stored potential energy and a variable flow resistor. In one aspect of the present disclosure, there is provided an infusion device that includes a plunger situated within a vessel so as to define a chamber within which a volume of fluid can be accommodated between a downstream surface of the plunger and the vessel. The infusion device further includes an outflow path through which the fluid in the chamber can be dispensed upon displacement of the plunger by a force acting thereon. A variable flow resistor is situated within the outflow path and is configured to allow a substantially constant fluid flow rate from the vessel to be maintained as the force acting on the plunger decreases.

Abstract: A hand-held remote for a medical fluid injector includes a syringe and a conduit which may be coupled to a pressure transducer on a control circuit of the injector. Movement of a plunger within a syringe body on the syringe creates a pressure which is sensed by the pressure transducer and the control circuit responds to the sensed pressure by causing fluid to be ejected from, or drawn into, a syringe mounted to the injector. The pressure developed by the remote provides tactile feedback to an operator for improved control over injections.

Abstract: A syringe plunger/jacket assembly may comprise a flexible jacket attached to a rigid plunger. The jacket may comprise at least two sealing rings (front and rear) that prevent fluid from leaking out of the rear of the barrel during injection of fluid from the syringe. The rear sealing ring may or may not contact or seal the interior surface of the syringe barrel in an unloaded state. In the loaded state, when force is applied in the direction of the forward discharge end of the syringe, pressure is created on the jacket. This condition causes the rear seal to expand and contact and/or seal the interior surface of the syringe barrel.

Abstract: Disclosed is a medical device used to prevent the cross-contamination of patients or injectors in which various components placed on the injector minimize or eliminate back splash contamination of the injector.

Abstract: Disclosed is a single-use syringe comprising a needle housing, a bore-containing fluid-delivery needle and a volume-containing element. The needle housing has a top surface to which the volume-containing element is attached, a needle attachment side to which the bore-containing needle is attached, and a fluid delivery channel in communication between the top surface and the needle attachment side. The volume-containing element is fluid-tight but for communication with the fluid-delivery and a filling port. Embodiments are disclosed which include vapor-permeable portions which facilitate lyophilization of materials in situ.

Abstract: An apparatus for endovascular repair of aortic aneurysms is disclosed. In one form, the apparatus includes a tube and an anchoring unit that includes a plurality of thin lines. The tube serves as a conduit for blood flow in an aneurysm of an aorta. First end of the lines are connected to a first end of the tube. Second end of the lines are separated by a distance from the first end of the tube for anchoring the apparatus at a location away from the aneurysm.

Abstract: Solid disks of polyethylene oxide are radiation crosslinked to instill viscoelastic memory. The disks are then pierced with a needle, heated, cooled and the needle removed to form disks containing a flow orifice in each which upon contact with water will revert to solid disks. A disk with a flow orifice made as just described when used as a memory flow control valve in a conventional injection device will produce a syringe with a single-use, auto-destruct capability. When the disk is inserted in a retainer in the flow channel of the injection device, a drug/vaccine can be drawn into the syringe and then expelled for a preselected time less than six minutes before the water in the drug/vaccine causes the flow orifice in the disk to close, the disk then reverting to its solid shape due to its viscoelastic memory.

Abstract: The invention relates to a portable and non-implantable device to enable a patient to self-administer, on demand, successive doses of a liquid while ensuring that the period of time between two successive administrations cannot be less than a reference value. The device has a liquid reservoir formed in a piston which can be pushed in a chamber to expel the contents of the chamber via an injection outlet and which is returned in the opposite direction by a return. The liquid reservoir communicates with the inside of the chamber via a passage formed through the piston and is provided with a flow rate limiter so that the time required to fill the chamber corresponds to a reference value. The invention is suitable for medical applications.

Abstract: A device for equalizing the pressure in the middle ear is comprised of a unit having one end that is to be positioned in a nostril and an opposite end that is provided with a rib. A balloon is positioned on the unit adjacent the rib. The unit is provided with a through hole whose smallest cross-sectional area is greater than or equal to 7 mm.sup.2. The elasticity of the balloon is such that a counter pressure of at least 20 mBar is produced upon being blown up.

Abstract: This syringe for dispensing multiple doses of a liquid medicament one at a time has a cylindrical barrel for containing the medicament. At one end of the barrel is a single outlet opening. A plunger in the barrel discharges the medicament. A syringe cap rotatable mounted on the barrel has guide means restraining the cap against axial movement. Ratchet means on the cap and barrel permit only unidirectional rotation of the cap and sequentially retain the cap in equally spaced detent positions on the barrel. Nozzles on top of the cap have passages for ejecting the medicament. Each passage terminates in a hole in the top of the cap. Only one nozzle at a time communicates with the barrel vis the outlet opening in each detent position of the cap on the barrel.

Abstract: A dispensing apparatus comprising a container adapted to house a fluid to be dispensed in sealed relation; an exposing member borne by the container for exposing the fluid for dispensing from the container through an opening; and a mount borne by the container adjacent to the exposing member operable to secure a needle or the like, through which the fluid can be passed, in fluid transferring relation to the opening of the container.

Abstract: A single use needle assembly includes a needle extending through a base with a hub extending from the base for engaging a syringe. The end of the needle within the hub has a port which is covered by a retractable sheath. When the needle assembly and a syringe are assembled, two separable tabs held within a basket force the sheath to retract and expose the port in the needle whereby a fluid can flow through the needle. Upon disassembly of the needle syringe, the tabs separate from the basket and are effectively destroyed for further use in retracting the sheath.

Abstract: An enema administering apparatus insertable into the rectum for delivery of a contrast medium to internal portions of a patient's anatomy includes an enema tube joined to an enema tip wherein the enema tube and enema tip have a common contrast medium passageway extending therethrough and an air passageway which is exterior of the contrast medium passageway and is able to be coupled to a source of air for double contrast studies. The air passageway may be a passageway disposed within the enema tube and enema tip construction or may be a separate tubing member joined therewith in a suitable arrangement to introduce air for the double contrast studies once the barium has been evacuated from the patient. Air introduction means and contrast medium introduction means are provided by various arrangements suitable for use with the main enema administering apparatus concept disclosed.