Abstract: A plug for insertion into the nose or ear of a subject, comprising: a body adapted to fit into a nostril or ear canal of the subject and a hollow tubular member with a collar disposed inside the body. The plug is adapted to receive a tip of a syringe for injection of a fluid therapeutic agent through the hollow tubular member for nasal administration or administration to the ear. A kit comprising the plug and a syringe, as well as a method for administering a fluid therapeutic agent to a subject using the plug are also disclosed.

Abstract: A plungerless aspiration and/or injection device and a method of using the same are disclosed herein. The plungerless aspiration and/or injection device includes a housing with an end portion extending outwardly from the housing, the end portion having an outer edge; a needle portion disposed in the housing, the needle portion including a needle tip, and the needle tip configured to be extended beyond the outer edge of the end portion of the housing; and a bulb portion disposed in the housing, the bulb portion defining a fluid containing cavity that is fluidly coupled to the needle portion, and the bulb portion being elastically deformable to perform aspiration, injection, and/or implantation on a patient. The outer edge of the end portion of the housing is configured to be pressed against a body portion of the patient prior to insertion of the needle tip so as to reduce a pain sensation.

Abstract: Provided is an enema nozzle for an enema device. Said enema nozzle includes an insertion body with a flexible insertion tip. The flexible insertion tip is located at the insertion end of the insertion body, and said tip will flex when it abuts intestinal tissue. This will provide a smoother insertion, which effectively will alleviate the physical discomfort and pain that a patient may expire during insertion of an enema nozzle.

Abstract: A gas-filled resilient body and uses thereof are described. The gas-filled resilient body may be used as a valve member, as a spring or as a gas-propelled dispenser.

Abstract: The invention discloses an anus cleaner, comprising a bottle body, wherein the inside of the bottle body is a hollow structure; the bottom of the bottle body is provided with a bottle bottom, and the bottle bottom is curved; the center of the bottle bottom is provided with a through hole, and a steel ball check valve is installed in the through hole; the end of the bottle body away from the bottle bottom is provided with a bottleneck, and the bottleneck is provided with threads; the bottleneck is equipped with a cleaning head; the bottom of the cleaning head is provided with threads, and the threads are provided on a mounting table; the mounting table and the bottleneck are matched and connected with the same size; the top of the mounting table is provided with a cleaning neck.

Abstract: A method of stimulating nasal tissues using a system comprises a catheter assembly connected to a fluid flow generator. The catheter assembly comprises a generally oblong inflatable catheter defining at least one catheter volume and a tube part comprising at least one lumen configured to establish fluid flow connection between said fluid flow generator and catheter. Preferably, the catheter assembly comprises at least one vent for releasing fluid or permitting fluid to escape from the generated fluid flow.

Abstract: The present invention relates to a device provided with a chamber that makes it possible to package at least one fluid, said chamber having a substantially ovoid form and comprising a first part made of a rigid material and a second part made of a flexible material, wherein the first part, made of a rigid material, comprises a dispenser that makes it possible to dispense said at least one fluid and wherein the second part, made of a flexible material is suitable for being deformed, thus making it possible to expel said at least one fluid from said device, by means of the dispenser.

Abstract: A wound irrigation device including a container with an opening along the outer surface of the container and a nozzle assembly coupled to the container and configured to selectively allow the liquid to exit the container when pressure is applied to the container.

Abstract: An applicator for a syringe is provided that includes a hub configured to be disposed at least partially within a nozzle of the syringe and defining a fluid passage therethrough, with one or barbs on the hub that frictionally and sealingly engage an interior of the nozzle in a manner minimizing void space associated with waste of deliverable material, and an applicator tip extending distally from the hub. The barb(s) may have varying diameters in order to enable the applicator to be engaged and utilized with syringes having different diameter nozzles. Further the fluid passage through the hub and applicator tip is dimensioned to minimize the volume of material that is retained within the applicator after use, thereby increasing the volume of material that can dispensed from the syringe for use in a procedure or procedures and minimize waste.

Abstract: Certain example embodiments relate to an air pump for balls, tires, toys, and/or the like and include a retractable base, which facilitates the storage of the needle(s) and/or other adapter(s) inside of the pump itself. This arrangement reduces the chances that it/they will break because it/they is/are protected inside of the pump and need not be repeatedly attached/detached. The pump in certain example embodiments includes a tube body into which the retractable base retracts, a plunger disk, a guide system including one or more guides for guiding the plunger disk and/or base within the tube body, a locking mechanism to help lock the base in extended and/or retracted positions, and a handle. The pump safely stores at least one needle/adapter in the tube body. In the event that a needle breaks, it may be replaced as if it were a conventional pump.

Abstract: Described is an anal medicinal applicator that generally comprises a base, a medicinal cream receiving port in the base, a shaft and at least one longitudinal slot. The longitudinal slot extending along an axis from the base and terminating at a distal end. The at least one longitudinal slot extending along a portion of the shaft, the receiving port, the shaft and the at least one longitudinal slot defining an unobstructed pathway. The longitudinal slot defined by a leading slot edge, a trailing slot edge, a proximal slot edge, and a distal slot edge, the leading slot edge and the trailing slot edge are longer than the proximal slot edge and the distal slot edge. A lip protrudes from the shaft along at least a portion of the leading slot edge it is configured and arranged to cause a tenting effect of the inner intestinal wall when the anal medicinal applicator is deployed in an anus.

Abstract: A cartridge (10) for injecting a pharmaceutical solution includes at least one flexible small bag (18, 22) made of thin film walls, having a chamber (12, 14) containing a pharmaceutical substance (S, P, L) and having a head surface (37) being outwardly convex. A syringe (100) for injecting a pharmaceutical solution (S) includes a body (102) extended along a main axis (X), an accommodating space (120) to accommodate a cartridge (10), and a plunger (110) with a head (113) being dome-shaped and convex towards the space (120), preferably asymmetrical with respect to the main axis (X). An injection kit for injecting a pharmaceutical solution including a syringe (100) and at least one cartridge (100).

Abstract: The present disclosure relates to an apparatus and a method. The apparatus comprises a body part and a cover part, wherein the body part and the cover part are configured to at least partially form a fluid channel between a surface of the body part and a surface of the cover part. The surfaces of the body part and the cover part may be facing surfaces. The method comprises manufacturing the apparatus according to the present disclosure.

Abstract: A single use delivery device is disclosed having a manually deformable liquid container defining an inner chamber, the container having a distal end, a body, a proximal end, and an outlet on the distal end; a tip projecting from the outlet on the distal end of the container, the tip in fluid communication with the inner chamber of the container; and a primer element for removing one or more air bubbles from the chamber, said primer element being attached to and in fluid communication with the deformable container. A method of administering a fluid to or flushing a vascular access device using a single use pre-filled delivery device as described herein is also disclosed.

Abstract: A syringe for the injection of an active substance and for the secondary injection of a medium, the syringe having a cylindrical syringe body with a limiting wall provided in the distal region, which transitions into a neck, two mechanically connected plungers that are axially displaceable in the syringe body, and a first actuating element for mutual displacement of the plungers, wherein, prior to the injection of the active substance, the distal plunger and the limiting wall delimit a first volume that is filled with the active substance, and mutually facing inner surfaces of the plungers delimit a second volume that is filled with the medium, wherein the plungers are displaced as a mechanically coupled unit by the application of force of the first actuating element in the direction of the limiting wall until the distal plunger comes to rest against the limiting wall or a stop.

Abstract: An apparatus for natural treatment for middle ear infection has a single use sachet. The sachet has a pocket that holds a limited quantity of mustard essential oil. The sachet has a neck and a dropper and the sachet can be squeezed to flow drops for pouring into an ear canal. The sachet is put in a microwave oven just before use for only substantially 30 seconds to heat the oil and up to five drops of heated oil is squeezed into an ear canal of a person with severe ear itching indicative of a middle ear infection.

Abstract: This disclosure relates to medical fluid pumping systems and related devices and methods. In some aspects, a medical fluid pumping system includes a medical fluid pumping machine including a piston head that can be linearly displaced and a medical fluid cassette that can be secured to the medical fluid pumping machine. The medical fluid cassette includes a fastening member attached to a region of a flexible membrane overlying a fluid pump chamber, and the piston head is configured to be mechanically connected to the fastening member of the cassette.

Abstract: A single use pre-filled delivery device is disclosed having a deformable container including a side wall having an inside surface defining a chamber for retaining fluid, a clip element, and a locking element. The deformable container further includes a closed proximal end and an open distal end including a male luer tip having a passageway therethrough providing fluid communication with the chamber. The male luer tip may be removably connectable to a female luer connection of a vascular access device. The clip element includes a distal end, proximal end, and a pivot located between the distal end and the proximal end of the clip element for collapsing the deformable container to drive fluid out of the chamber by movement of the proximal end towards the distal end.

Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid. The reservoir chamber has a fluid outlet. The cartridge further comprises a controllable dispenser component for dispensing a dispensing volume of the fluid from the reservoir chamber. The dispenser component is connected to the fluid outlet of the reservoir. The cartridge further comprises a single compressible fluid pump with a single elastic pumping element and a conduit extending from the fluid pump towards the fluid outlet. The fluid pump discharges a mixing volume of the fluid from the conduit into the reservoir chamber upon compression of the elastic pumping element. The mixing volume depends on the degree of compression of the elastic pumping element. The fluid pump sucks in the mixing volume from the reservoir into the conduit upon decompression of the elastic pumping element.

Abstract: Methods and apparatus for a syringe adapter. In one embodiment, an adapter/cap assembly is threadably engaged to a syringe for enteral feeding applications. The adapter cannot be removed from the syringe to prevent the syringe from being used for IV applications.

Abstract: A portable functional vaginal cleansing apparatus is provided to prevent inflammation in vagina, to maintain cleanness, and to enhance massage effect. A portable functional vaginal cleansing apparatus comprises: a doughnut-shaped main body; a semicylinder water tank with a water level indicator (100) on the outside and a coupling protrusion inside; a handle part (380) with a coupling groove mounted at the coupling protrusion; a pumping unit (210) with a motor and a pump; and a control unit (290) with a rotator which is formed to rotate within a predetermined range, a insertion protrusion connected to a hose, an insertion unit with a nozzle part, an on and off switch, a water level controller, and an operation lamp.

Abstract: A system in accordance with embodiments of the present invention includes a permeable tissue collection vessel or filter element disposed within a collection container. Collected tissue is deposited within the filter element through an inlet. Fluid that passes through the filter element is withdrawn from the collection canister through an outlet. An access port can be provided in a lid of the collection container to facilitate the removal of collected tissue from the tissue collection vessel.

Abstract: Methods, apparatuses, kits and systems are disclosed that allow a transfer of medication from a manufacturer's vial, ampoule or other container through a closed system transfer to an intravenous apparatus and into a patient, while reducing additional steps, procedures, components required for the same transfer procedure to reduce sources of human error and medical administered errors.

Abstract: A single use pre-filled delivery device comprising a deformable container, a one-way valve, and male luer connector is described. Also described are methods of flushing vascular access devices using a single use pre-filled delivery device as described herein is also disclosed.

Abstract: An applicator 270 includes a stem 174 having an axially-formed slot delivery passage 200. A slot 176 is formed transaxially through the stem 174 and is in communication with the slot delivery passage 200. An extended side wall 176b is formed on one side of the slot 176. A flat surface 276 is formed in the stem 174 and extends angularly away from an opposite side of the slot 176 and from the extended side wall 176b to provide a wide slot opening at an external surface 195 of the stem for dispensing a cream from the opening. A trough-like cleft 306 can be formed in the external surface 195 of a solid portion of the stem 174, distally of the slot 176, to provide an axially-extended path for the cream being dispensed through the slot.

Abstract: An earwax cleaner includes a bag-shaped holding portion and a soft earwax picking sleeve. The rear section of the bag-shaped holding portion is provided with a resilient bag-shaped body, and the front section is a pipe with an opening. The earwax picking sleeve has a reduced mouth at the distal end and a plurality of protrusions on an outer wall thereof. The earwax picking sleeve is fitted on the pipe of the holding portion. The opening of the pipe is aligned with the mouth of the earwax picking sleeve to form an open end for the air in the bag-shaped body of the holding portion to pass in and out. When in use, the pipe is inserted in the ear and the holding portion is slightly turned with the protrusions to pick the earwax from the wall of the ear to be collected in the bag-shaped body.

Abstract: A medicant injection device includes a compressible body, a tip, and an outer luer body. The compressible body has a proximal end, a distal end, and a plurality of bellows, and defines an inner cavity for holding a liquid medicant. The tip is positioned at the proximal end of the compressible body. The outer luer body includes internal threads, and is positioned over and engaged with the tip to form a first fitting therewith. The first fitting is configured to be connected with a second fitting. A medicant injection device includes a compressible body having first and second arms, a receptacle interconnected with the compressible body and defining an inner cavity, and a first fitting configured to engage a second fitting. The compressible body is configured to be compressed by forcing the distal end of the first and second arm toward each other.

Abstract: The present invention relates to a self-injection mechanism that causes a solution (2) having predetermined efficacy to permeate the skin (1) for skin improvement and beauty treatment. The present invention includes: an accommodation unit (10) having a space (11) therein for accommodating the solution (2), an inlet (12) which sucks only air at one end, and an outlet (15) which is open so that the solution (2) is discharged at the other end; a pumping unit (20) coupled to the outlet (15) of the accommodation unit (10) so as to be in communication with the same, having an airless pump (21) which discharges the solution (2) by an up and down movement at the center; and an injection unit (30) coupled with the airless pump (21) of the pumping unit (20) so as to be in communication with the same, causing the solution (2) which is discharged by the up and down movement to permeate the skin (1).

Abstract: A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5?, 6, 6?) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27?, 28?) on the distal end of a cartridge assembly (20).

Abstract: An enema includes a liquid in a dispenser having a bottle, a nozzle attached to the bottle, and a valve. The valve may be a membrane having a slit and a thickness of at most 0.90 mm. The valve may be attached to the bottle or it may be attached to the nozzle. The enema can be administered more easily, with a lower amount of force. A method of bowel cleansing includes inserting the enema into a rectum and applying a compression force to the enema bottle.

Abstract: A device for nasal lavage is described. The device ejects a gentle flow of fluid under pressure. The fluid stream provides a high quantity of fluid at low pressure. The low pressure fluid stream is more comfortable for a user than a high pressure fluid stream that is delivered by some types of pressurized cans of solution.

Abstract: The present invention relates to a method for the administration of a probiotic composition to a vaginal cavity and to compositions, devices and kits for use in this method.

Abstract: A nasal aspirator is adapted to remove fluid or tissue from a nasal passageway. The aspirator includes an aspirator tube sized to fit in a nasal passageway.

Abstract: An apparatus for natural cure for middle ear infection has a single use sachet. The sachet has a pocket that holds a limited quantity of mustard essential oil. The sachet has a neck and a dropper and sachet can be squeezed to flow drops for pouring into an ear canal. The sachet is put in a microwave oven just before use for only substantially 30 seconds to heat the oil and up to five drops of heated oil is squeezed into an ear canal of a person with severe ear itching indicative of a middle ear infection.

Abstract: Formulations and methods of manufacture are provided for granisetron dry powder compositions suitable for intranasal administration. Also provided are methods of use for preventing or controlling emesis and other diseases and disorders and devices, compositions, and methods for nasal delivery of therapeutic formulations. Devices for delivery of dry powder formulations are also provided. Devices can be single-use devices.

Abstract: A dispensing container according to the invention includes a container body having a rod-like shape. The dispensing container is therefore compact and the user can hold the dispensing container as if the user holds a pen and use the thumb, the index finger, and any other finger to apply pressure to the dispensing container so as to dispense a drug solution. A heat insulating grip is attached to the outer circumferential surface of the container body, whereby heat originating from the body temperature of a finger of the user will not be transferred to the drug solution or volatilize it. No excessive dispensing that is not intended by the user will therefore occur. Since the container body is thin and hence unlikely crashed, the user can make adjustment of the pressure applied by the thumb, the index finger, and any other finger to readily extract a single droplet.

Abstract: A device for nasal lavage is described. The device ejects a gentle flow of fluid under pressure. The fluid stream provides a high quantity of fluid at low pressure. The low pressure fluid stream is more comfortable for a user than a high pressure fluid stream that are delivered by various types of pressurized cans of solution.

Abstract: A single use pre-filled delivery device comprising a deformable container, a one-way valve, and male luer connector is described. Also described are methods of flushing vascular access devices using a single use pre-filled delivery device as described herein is also disclosed.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: Described generally herein are tissue therapy devices, which may comprise a sealant layer and a suction apparatus. The sealant layer functions so as to create a sealed enclosure between it and the surface of a patient by forming, preferably, an airtight seal around an area of tissue that requires negative pressure therapy. The tissue therapy device may comprise a suction apparatus. The suction apparatus is typically in fluid communication with the sealant layer and functions so as to reduce the amount of pressure present underneath the sealant layer. The reduced pressure is self-created by the suction apparatus. Together the sealant layer and the suction apparatus preferably create a closed reduced pressure therapy system. Preferably, the pressure under the sealant layer is reduced by expanding the volume of the enclosure space and thereby decreasing the density of the air molecules under the sealant layer.

Abstract: A device for nasal lavage is described. The device ejects a gentle flow of fluid under pressure. The fluid stream provides a high quantity of fluid at low pressure. The low pressure fluid stream is more comfortable for a user than a high pressure fluid stream that is delivered by some types of pressurized cans of solution.

Abstract: An administration device can discharge a prescribed, equal amount of medicine a number of times by spraying. A spraying device includes a barrel; a gasket provided slidably movable in liquid-tight manner in the barrel; a rod coupled to a base end of the gasket; and a regulating member provided on the barrel, having a projection that can slidably fit with the guide groove. The guide groove includes at least first and second continuous administering grooves. The second administering groove is configured to include a transitional portion extending in the circumferential direction with a groove wall on the base end side aligned with the base end of the first administering portion, and a second administering portion extending from the transitional portion to a base end along the longitudinal direction. An energizing protrusion engageable with the projection is provided at a boundary between the transitional portion and the second administering portion.

Abstract: A personal cleaning apparatus includes a housing that has a bottom wall and a peripheral wall. The peripheral wall has an upper edge defining an opening into the housing. A conduit has a first end and a second end and a perimeter wall extending between the first and second ends. The first and second ends are open. The upper edge of the peripheral wall is integrally attached to and coextensive with the conduit and the conduit is in fluid communication with an interior of the housing. An applicator includes a body portion and a top wall. The body portion has an open distal end with respect to the top wall that is positioned in the conduit. The top wall has a plurality of apertures extending therethrough. The housing may be filled with fluid, the applicator inserted into a person's body and the housing squeezed to eject the fluid.

Abstract: A drug solution filling plastic ampoule having gas, steam and light ray barrier properties, a drug permeation preventing capability and an absorption/adsorption preventing capability, and a production method for the plastic ampoule. The drug solution filling plastic ampoule includes a container body, a fusion-bonded portion which seals a mouth of the container body, and a wrench-off holder tab connected to the fusion-bonded portion. The ampoule is formed from a parison including two or more layers, at least one of which is a functional layer having at least one characteristic property selected from the group consisting of a gas permeation preventing capability, a steam permeation preventing capability, a light ray permeation preventing capability, a drug permeation preventing capability and a drug absorption/adsorption preventing capability.

Abstract: A high flow volume nasal irrigation device for alternating pulsatile and continuous fluid flow includes a tube comprising a free end and a housing at a second end adjoined to a cap with a coaxial cap nipple. A valve assembly inside the housing comprises a disk-like valve and a plurality of housing standoffs configured to stop the valve but allow a fluid flow in the housing and out the nipple. A cylindrical elastic valve seat is adjoined to the cap nipple and forms a gap with the valve on the standoffs. A spring opposes the valve moving toward the valve seat from the standoffs and assists in returning the valve from the seat to the standoffs and thus with the valve seat creates a periodic pulsatile fluid flow in the nipple in response to a chamber pressure which exceeds a critical chamber pressure threshold.

Abstract: A syringe comprises a barrel with a plunger in slidable and sealing engagement therein, and a needle attached to one end of the barrel. The barrel has an aspiration device in the form of manually-operable resilient portions, which can be operated to cause a pressure differential in the barrel, the pressure differential then being used to perform aspiration. The resilient portions are preferably formed by localized reductions of wall thickness in the external surface of the barrel.

Abstract: A pneumostoma management system includes a pneumostoma management device for maintaining the patency of a pneumostoma while controlling the flow of material through the pneumostoma and a pneumostoma aspirator for pneumostoma care. The pneumostoma aspirator includes a bulb or syringe for applying positive or negative pressure, a tube for entering the pneumostoma and a limiting device for limiting the depth of insertion of the tube into a pneumostoma. The pneumostoma aspirator may also be used to introduce irrigation fluid into the pneumostoma and/or remove irrigation fluid and discharge from the pneumostoma.

Abstract: The portable enema device of the present invention can be used by patients experiencing bowel trouble such as constipation and is especially convenient for individuals to carry and use at any time. The portable enema device includes: an insertion nozzle; a tube-type manual pump; a supply hose; an upper cap which is detachably fastened to an upper end of the tube-type manual pump in a screw coupling manner; an inner supply tube which extends into the tube-type manual pump; a sliding pipe which is formed with an infusion solution supply path and is placed under the tube-type manual pump; and an inner sliding pipe provided in the shape of a concentric circle.

Abstract: An ear medication delivery device for delivering a treatment liquid and retaining the treatment liquid within an ear canal of a patient including a unitary, one piece earplug formed of a soft resilient material including an ear canal engaging portion and an external portion and defining a single internal passage therethrough. The external portion includes a major disk and an annular medication applicator receiving portion in fluid communication with the internal passage. The ear canal engaging portion includes at least two minor disks of progressively different size extending outwardly in a generally radial direction. The ear canal engaging portion defines a molded resilient valve unitary with the earplug that is shiftable from a closed position to an open position in either direction under a preselected fluid pressure and that resiliently returns to the closed position below the preselected fluid pressure.

Abstract: The invention relates to a medicament container (1) for a liquid medicament, the medicament container (1) comprising a flexible bag (2) with an outlet (4), the bag (2) surrounded by a braid (3), arranged for lengthening and narrowing when being pulled in longitudinal direction (L).