Abstract: A single-use syringe has a barrel which can constitute a one-piece extrusion, and a shank which is reciprocably guided in the barrel and the distal end of which carries a plunger movable in the barrel toward and away from the needle-carrying front end portion of the barrel. The coupling between the plunger and the shank includes a set of circumferentially spaced-apart breakable spokes which can be of one piece with the distal end of the shank as well as with the plunger. The spokes break not later than when the shank completes a forward stroke during which the plunger expels a flowable substance, such as a medicine, from a chamber located in the barrel between the needle-carrying front end portion and the plunger. The plunger, the spokes and the shank can constitute a one-piece extrusion.

Abstract: A disconnectable connection between a plunger and a plunger rod in a medical delivery system is provided. The plunger comprises a spherical or semi spherical shaped cavity, which is fully encapsulated in the interior of the plunger and connected to the back wall of the plunger through an open orifice. The Plunger rod has a spherical or semispherical portion provided at the distal end, which portion enters into the plunger cavity when the two parts are connected. In order to allow air in the plunger cavity to escape during plunger rod connection, is either the distal portion of the plunger rod or the open orifice in the plunger back wall provided with tracks, slots, apertures or similar geometries.

Abstract: The syringe (10) comprises a detachable syringe barrel (14) connected to a housing (12). The housing contains a drive means connected to a plunger (24). The drive means is for extending and retracting the plunger into and out of the detachable syringe barrel. The detachable syringe barrel comprises a stopper (26) at one end thereof in sealing engagement with the interior of the barrel and for releasable engagement with the end of the plunger distal to the drive means. At least a portion of the stopper is flexible between a first position and a second position. In the first position, the flexible stopper may be disengaged from the plunger upon retraction of the plunger away from the detachable syringe barrel. In the second position, the flexible stopper is maybe engaged with the plunger upon extension of the plunger toward the detachable syringe barrel.

Abstract: Three collar groups 6A through 6C, each group comprising collars 5a through 5b, 5c through 5e and 5f through 5h which are thin walled and close to each other are provided in a spaced manner in a piston sliding direction. A first group 6A which is provided at the front most end of the piston head 5 comprises two collars 5a and 5b. The front collar 5a which is in contact with the liquid drug has a larger diameter than that of the rear collar 5b. First and third collar groups 6B and 6C which are at the rear of the first collar group 6A comprise three collars 5c to 5e and 5f to 5h, respectively. The intermediate collars 5d and 5g have larger diameters than those of the front and rear collars 5c and 5e; and 5f and 5h, respectively. A support collar 5i is provided at the rear of the collar groups 6B and 6C in such a manner that it is spaced therefrom. The support collar 5i has a thick walled portion x at its base excepting the peripheral edge thereof.

Abstract: By a cylinder ampoule (1), comprising a tubular vessel with a membrane (4) sealingly closing one end and a piston (9) closing the other end, liquid stored between said piston (9) and said membrane (4) can be pressed out through an injection needle (7) piercing the membrane (4) when the piston (9) is pressed into the ampoule (1). The tube is made from a plastically deformable material. A pressure foot (10) on which a piston rod (13) is acting abuts the piston (9), carries a spring plate (11) made from a harder material than is the ampoule (1), is mainly perpendicular to the ampoule (1) axis, and has at least one diameter which is larger than the inner diameter of the ampoule (1) so that edges of the plate (11) abutting the inner wall of the ampoule (1) are deflected away from the piston (9) to form an acute angle with said wall.

Abstract: A front-loading syringe which comprises a movable plunger for injecting liquid contrast media, is rotatably mountable on a front wall of an injector housing with an interference fit and in sealed relationship with respect thereto, with or without a pressure jacket, by a first-quick release mechanism. At the same time, the plunger is connected to an injector drive mechanism by a second readily releasable mechanism. During the mounting operation, a sensor reads injection information from an indicator device on the syringe and feeds it to an injector control. An audible-and-tactile indicating mechanism also is activated when the syringe is essentially in the desired mounted position. The syringe may include reinforcing ribs which also function as volumetric gradations, and liquid media presence-or-absence indicating dots which appear circular against a liquid media background and oval-shaped against an air background.

Abstract: This invention relates to a vaginal/ano-rectal applicator for the uniform delivery of any topical formulations to treat and/or prevent any infection and/or abnormal conditions of mucosa cavity caused by any pathogen and/or disease. The present applicator comprises a longitudinally extending body that has proximal and distal ends. The proximal end is located close to the external site of a mucosal cavity accessible to a user. The body has external perforations, made as a series of slots or holes, for uniform distribution of any formulation to be delivered to the user's mucosal cavity. Upon insertion of the applicator and expulsion of the formulation in the mucosal cavity, the formulation, which is contained in a reservoir, travels through a diffusion channel having a small volume, prior to being expelled through the perforations.

Abstract: Adapters for use with an angiographic injector. A face plate adapter includes a channel for receiving a rearward end of a syringe. First and second mounting flanges on the adapter overlay a portion of the channel, to cooperate with mounting flanges on a rearward end of the syringe, so that the syringe mounting flanges may be inserted between the adapter mounting flanges, and then rotated in the channel behind the adapter mounting flanges, to thereby lock the syringe to the adapter. The adapter further includes one or more locking pins, which in a locked position extend across the channel, to block the syringe from rotating in the channel and thereby prevent a syringe from being dismounted from the adapter. A collar incorporated in the adapter interacts with a drive ram of the injector to move the locking pins into their locked position whenever the ram is forward of a rearwardmost position.

Abstract: A syringe adapter, which permits use of syringes of various types and sizes to be used with a front-loading injector, includes a piston extension and an adapter face plate. The piston extension includes structure for connecting the piston extension to a drive piston of the injector and a plunger of the syringe. The adapter face plate includes a mounting device for attaching the adapter face plate to an injector and a recess for receiving the distal flange of the syringe. The adapter face plate may also include locking pivot arms for releasably engaging the syringe flange.

Abstract: A plunger rod for a syringe in is of integrally injection molded plastic construction having an elongated body with a coaxial end portion. An external thread extends around the end portion for threaded receipt into a plunger tip that is slidably received in a syringe barrel. A flat extends chordally across the end portion of the rod body interrupting the external thread. The plastic, of which the plunger rod is molded, is gated into the mold for the plunger rod at the flat that extends across the rod end portion, leaving a gate mark or vestige on the flat. Gating of the plastic material into the portion of the mold that forms the threaded end portion of the plunger rod achieves improved flow and improved filling of the external thread, while employing a simple and economical mold construction. The gate vestige does not interfere with threading of the plunger rod end portion into the plunger tip.

Abstract: A syringe includes a needle mounted in a frangible plug at the tip thereof and is equipped with a plunger having a stopper at one end thereof with the end of the plunger having an opening for capturing the end of the needle that projects into the barrel of the syringe to allow the plunger to capture the needle so that when the plunger is retracted the needle will be withdrawn into the barrel of the syringe; the end of the plunger is also equipped with a stopper which is mounted on a section that is connected to the plunger through frangible links whereby when the plunger is withdrawn a selected distance, the links will be severed to retain the plunger and captured needle within the barrel.

Abstract: A device for injecting fluid from a pre-filled cartridge is provided. The device includes a needle for piercing a patient. After an injection, the needle can be retracted to prevent inadvertent contact with the contaminated needle. A needle retainer releasably retains the needle in the retracted position. The needle can subsequently be re-extended to administer a subsequent injection. After the cartridge is emptied, the cartridge can be removed, if desired, and replaced with another cartridge for additional injections. Alternatively, the needle can be retracted into the device and safely disposed of in a sharps container.

Abstract: A safety syringe comprises a barrel having a retaining block disposed in the receiving hole, an initial stop portion and a final stop portion disposed in the end edge thereof, and a rotation resisting portion; a needle holder disposed in the barrel, and having a retaining groove and communicating with a port, a rotation stopping rod corresponding between the initial stop portion and the final stop portion of the barrel, overcoming portion capable of passing the rotation resisting portion of the barrel; and a plunger capable of catching and turning the needle holder. As the plunger is not engaged with the needle holder, the retaining groove of the needle holder confines the retaining block of the barrel.

Abstract: A hypodermic syringe comprises a barrel having at least one catching piece disposed at the end; an outer sleeve fitted rotatably with the barrel to turn to locate at the first position and the second position and provided at least one escape hole; a needle holder having a cylinder cooperating portion disposed slidably in the receiving hole of the barrel, a retaining circular groove disposed in the outer periphery of the needle holder for retaining the catching piece of the barrel; a plunger having a rod body capable of pulling back the needle holder. As the outer sleeve is turned to the first position, each catching piece of the barrel retains the retaining tooth of the barrel. The needle holder is unable to displace. As the outer sleeve is turned to the second position, the escape hole is corresponding to the catching piece of the barrel to eject outward. The needle holder is not confined so as to be pulled back by the plunger.

Abstract: An applicator for administering a medication to an animal, particularly a mastitis treatment, is made up of an elongated syringe having an integral blunt-tipped cannula provided at one end thereof. The cannula has a first portion for partial insertion of the cannula and a second portion for complete insertion of the cannula. The diameter of the cannula first portion is smaller than the diameter of the cannula second portion and the cannula first and second portions join at an annular shoulder which limits the partial insertion of the cannula.

Abstract: A pre-filled syringe having an elastic-sliding valve to produce a hermetic closure inside a pre-filled syringe which keeps the liquid content to be injected totally isolated, in order to prohibit the liquid from coming in contact with the needle or the external air.

Abstract: A syringe includes a barrel having a fluid chamber, a proximal end, a distal end and an elongated tip extending from the distal end and having a passageway therethrough in fluid communication with the chamber. A collar surrounds the tip and includes at least one deflectable locking tab projecting radially inwardly from the collar. The locking tab is adapted to engage the hub of a needle assembly to prevent removal of a needle assembly away from the tip. The locking tab is configured to allow the assembly of the needle assembly to the barrel through axial motion of the hub toward the barrel. A plunger is provided for drawing fluid into and out of the barrel. The plunger includes an elongated plunger rod having a proximal portion and a distal portion connected by a breakable connection. The breakable connection is strong enough to hold the proximal portion and distal portion together during normal use of the syringe and breakable upon application of additional force to the proximal portion.

Abstract: A injection system having a syringe body which defines a pumping chamber. A syringe plunger is located in the pumping chamber and is adapted for reciprocal motion within the pumping chamber. The syringe plunger includes a capture member projecting outwardly in a proximal direction. An actuating shaft is coupled to the syringe plunger and is movable through the syringe body to control movement of the syringe plunger. The capture member is adapted to flex radially outwardly when contacted by the actuating shaft to form a releasable engagement with the actuating shaft when the actuating shaft and the capture member are in an engagement position. A release actuator is disposed proximal to the syringe body, and the capture member releases the actuating shaft upon engagement with the release actuator.

Abstract: An animal fluid injector, replaceable syringe and method of replacement of the syringe in the injector are provided in which the syringe is loadable and unloadable into and from the injector through the open front end of a pressure jacket of the injector, thereby permitting replacement without retraction of the syringe plunger drive or disconnection of the injection tubing. The syringe is provided with a pressure restraining front end, such as an integral or removable cap with structure such as threads that lock the syringe to the front end of the jacket by mating with threads on the jacket. A mechanism in the injector, which includes, for example, a key or cam ring operated by a lever with one hand of an operator, interacts with structure such asymmetrically spaced notches on the back end of the syringe to, for example, rotate the syringe and simultaneously translate or rotate a coupling on the syringe plunger into and out of engagement with the plunger drive in the injector.

Abstract: A device for dispensing fluid products having a dispensing member (1), such as a pump, mounted on a container (2), and an actuating member (3), such as a thruster, for dispensing the product. The device has two reservoirs of products (10, 20) arranged such that they are successively emptied, the product contained in the second reservoir (20) being dispensed only when the first reservoir (10) is empty, characterized in that the first reservoir (10) is fixed to the body of the dispensing member (1) or to a support piece (9) of the body, and extends to the bottom of the container at least partially inside the second reservoir (20).

Abstract: A syringe includes a barrel having a fluid chamber, a proximal end, a distal end and an elongated tip extending from the distal end and having a passageway therethrough in fluid communication with the chamber. A plunger is provided for drawing fluid into and out of the barrel. The plunger includes an elongated plunger rod having a proximal portion and a distal portion connected by a breakable connection. The breakable connection is strong enough to hold the proximal portion and distal portion together during normal use of the syringe and breakable upon application of additional force to the proximal portion.

Abstract: Disclosed is a syringe plunger adapted for use with a glass syringe barrel to provide a low friction syringe useful in medical procedures such as administering epidural anesthesia, the plunger having a first or leading member and a second or trailing member, the first member comprising a hollow glass tubular body defining a chamber having a closed leading end and an open trailing end, the first member being characterized as adapted to provide a very close tolerance fit within the glass syringe barrel and as exhibiting substantially no frictional interference as the leading end of the first member is advanced axially within the syringe barrel; the second member having leading and trailing ends; and means for flexibly securing the leading end of the second member within the chamber of the first member so that the second member is free to flex at the point of attachment in response to lateral forces applied to the second member as the plunger is advanced within the glass barrel, the plunger thereby being charact

Abstract: In a plunger for a syringe including a laminated piston which is provided with a shaft with a female thread and which is slidably inserted into a barrel and a rod having a male thread which can be screw-engaged in the threaded hole of the laminated piston, the axial length T of the crest of the female thread and the root of the male thread which engages with the female thread is greater than the axial length t of the root of the female thread and the crest of the male thread.

Abstract: A disposable auto-destruct syringe is disclosed which includes a syringe barrel for holding an injectable fluid, a piston reciprocatable in the barrel and sealingly engaging the barrel wall, a plunger having a forward portion normally positioned in the barrel and a rearward portion to be manipulated by a user of the syringe, a coupling mechanism for connecting the piston with the plunger to permit axial movement of the piston in the barrel by operation of the plunger, and a deforming structure for permanently deforming the barrel wall to break the seal between the piston and the barrel wall. The deforming structure is in the form of cutters or burrowing elements mounted by-way of elastic arms to one of the piston and the plunger. The deforming structure is movable from an at rest position wherein the barrel wall is not deformed, to a barrel wall engaging position wherein the barrel wall is permanently deformed by the deforming structure.

Abstract: An injection device comprising a) a housing, b) a cartridge containing a preparation or precursor components for the preparation and having a front part and a rear part defining a general cartridge axis, an outlet for the preparation arranged at the front part and at least one movable wall arranged between the front part and the rear part, a displacement of which wall causes the preparation to be moved towards or expelled through the outlet, c) a piston rod, having a first end and a second end, at least partly contained within the housing and being operable to engage and displace the movable wall at its first end and d) actuating means within the housing arranged to move at least the rod.

Abstract: The present invention provides a syringe and a powered injector for use therewith in which the syringe is attachable to a powered drive member of an injector over a range of relative axial positions of the syringe plunger and the drive member. The syringe comprises a plunger, and a plunger extension connected thereto and extending rearward from the plunger, such that the syringe may be operated manually or by a powered injector. In one embodiment, the plunger extension comprises a plurality of plunger attachment members located over a range of axial positions on the plunger extension. Each of the plurality of plunger attachment members is adapted to form a releasable attachment with at least one cooperating injector attachment member on the powered drive member.

Abstract: An apparatus for delivering fluid, or power syringe, comprises a base, a lever, and a syringe. The syringe has a reservoir adapted for holding a quantity of fluid and a plunger disposed within the reservoir and adapted for movement therein. The reservoir features a clip on one end which releasably secures the end of the reservoir to the base and an inwardly facing annular flange on the second end which substantially prevents the plunger from being removed from the reservoir and substantially prevents leakage. The base of the apparatus features an extension beyond the end of the reservoir containing the clip, thereby providing stability to the apparatus during operation. The plunger features a clip on one end which releasably secures the plunger to the lever.

Abstract: A self-destructing hypodermic syringe (1) comprising an optionally graduated barrel (2) having a Luer lock-tip (13) in one end and a plunger head (5) with plunger rod (3), of the type which has a breaking element (4) incorporated in connection with the plunger head or plunger rod, and where the breaking element (4) is broken when the syringe (1) is used for the first time, wherein the breaking element (4), is cast in one piece with the plunger rod (3) and initially, prior to destruction, is secured thereto via diametrically arranged cam follower hoops (6) and lugs (7) which, when loaded, are broken at perforations (7') while converting the lugs (7) to cam followers (7).

Abstract: The invention provides a handheld, manually operable fluid applicator, particularly suited to the needs of surgeons, which can dispense multiple medically useful fluids, for example fibrin and thrombin components of a tissue adhesive, and which has a smooth feel and action. The applicator has a novel actuator mechanism providing a comparatively higher mechanical advantage in a commencement phase of the actuator stroke and a comparatively lower mechanical advantage in a completion phase of the actuator stroke.

Abstract: A syringe assembly has a cylindrical hole extending between the inside and outside of the syringe body for attachably and detachably carrying a holding member that in turn carries a liquid flow tube (e.g., a needle or similar tube). The holding member seals with the syringe body and permits the flow tube to communicate between the inside and outside of the syringe body. The holding member has a main body that is axially insertable into the installing hole and can be axially pulled from the installing hole into the syringe body after the plunger is advanced to engage the holding member. An annular groove or a projection on the outside of the holding member fits with a corresponding projection or groove on the inner wall of the installing hole to seal the holding member to the syringe body along a plane perpendicular to the axis.

Abstract: A sliding piston for a syringe, which is inserted in a hollow barrel of a syringe is made of a substantially cylindrical body having a shape symmetrically rotatable with respect to the axis of the hollow barrel. The cylindrical body has its largest diameter at the front end thereof. The peripheral edge of the front end of the cylindrical body is rounded at a radius of curvature of 5/100 mm to 10/100 mm. The diameter of the rear end of the cylindrical body is smaller than the inner diameter of the hollow barrel so as not to contact with the inner surface of the hollow barrel when the piston is inserted in the hollow barrel.

Abstract: The hollow cylindrical syringe body has a channel of uniform diameter. A fluid port is situated at one end. The other end defines a funnel-like opening with a diameter greater than that of the channel. A piston is moved along the channel by the end of a push rod which is received through the channel opening. A ball on the push rod lodges in a socket in the piston as the rod pushes the piston toward the port. The socket is formed of resilient fingers which are held by the channel wall in position to retain the ball in the socket, such that the piston can be moved along the channel to load the syringe. When the socket aligns with the funnel-like opening of the channel, the socket fingers spread apart to release the ball from the socket, permitting the push rod to be removed from the loaded syringe.

Abstract: The present invention is directed toward a plunger provided for use in a nozzle assembly. The nozzle assembly includes an internal chamber with an outwardly tapered portion at one end thereof. The plunger includes a plurality of outwardly curved prongs or legs which mate with an inwardly tapered portion of the internal chamber in order to allow the piston of the injector to be released from the plunger. As a result, the plunger may be removed from the injector when the nozzle assembly is removed therefrom. This plunger may include a frangible portion so that, upon firing, a first driving member of the plunger breaks away from a second driving member of the plunger. As a result of this frangible connection, the first driving member remains lodged in a distal portion of the chamber to prevent reuse of the nozzle assembly.

Abstract: A syringe assembly has a hub body which can be inserted into a hub insertion hole and pulled out thereof into inside a sringe body. A chamfer portion is formed at the hub body, being capable of engaging with the hub insertion hole. A needle insertion hole capable of being inserted a needle therein is provided with an end face of the hub body in a direction of an axis center of the hub body. A flow hole is provided with the hub body such that the needle insertion hole and an inside of the syringe body are communicated with each other in the direction of the axis center. A piston engagement hole is provided on end face side of the hub body, so as to engage with the piston. A seal taper is annularly formed at the hub body, such that its outside diameter is made narrower for the end face side, so as to abut on and contact with an inner face of the hub insertion hole.

Abstract: A single-use syringe assembly is provided and includes an elongated syringe barrel with a plunger assembly disposed therein. The plunger assembly includes an elongated plunger rod having a plunger tip located distally. The plunger tip contains a locking detent disposed a the distal end of the tip. The syringe barrel has a nozzle at the substantially closed distal end, the nozzle adapted to conform to the plunger tip. The distal end of the nozzle contains an annular inward biased ring adapted to mate with the locking detent of the plunger tip. Upon usage of the syringe and application of force to apply the liquid, the locking detent is irreversibly mated with the nozzle inwardly biased ring, thereby preventing reuse of the syringe assembly.

Abstract: A syringe stopper for use in a syringe barrel having a substantially cylindrical body comprises a piston-like stopper body for slidable fluid-tight engagement inside the barrel of the syringe. The body includes a distal end, a proximal end and a longitudinal axis therethrough. A distally directed, conically-shaped projection is positioned on the distal end of the stopper body. At least one elongate discontinuity, running along the conically-shaped projection, is provided. The discontinuity includes a first end on the conically-shaped projection and extends radially outwardly therefrom to a second end, as viewed from the distal end of the stopper. The discontinuity may be in the form of a raised rib or a recessed groove.

Abstract: The invention relates to a pre-filled disposable syringe to be used in the administration of powdered drug diluted at the time of injection. The novelty resides in that the plunger head, along with an elastomer head, constitute a particular valve acting as a function of plunger displacements.

Abstract: A hub to be attachably and detachably inserted into a hub insertion hole of a syringe body having a hub insertion hole cylindrically formed at a top thereof has a cylindrical hub body through which the hub can be inserted into the hub insertion hole and can be pulled out of the hub insertion hole in a syringe body. At an outer peripheral portion of the hub body, a hub stop groove in the shape of a groove is annularly formed capable of engaging with the hub stop rib. At an end face of the hub body, a needle insertion hole capable of inserting a needle therein is provided. A flow hole is provided with the hub body such that the needle insertion hole communicates with the inside of the syringe body. At an end face of the hub body, a piston engagement hole is provided so as to engage with the piston.

Abstract: A nonrefillable syringe including a unique plunger stem/piston arrangement which is designed to disconnect after an injection has been completed. A piston is removably connected to a plunger stem by a first connecting member and a novel nipple assembly. The first connecting member comprises a plurality of circumferentially spaced arms extending longitudinally away from the piston and forming an interior aperture. The nipple assembly includes a tapered nipple removably matable with the aperture formed by the circumferentially spaced arms of the first connecting member, and a cylindrical carrier for slidably positioning the nipple assembly within a hollow end of the plunger stem. The tapered nipple is gradually forced out of the aperture during use of the syringe. When the tapered nipple is forced completely out of the aperture, the piston disconnects from the plunger stem.

Abstract: An article of manufacture adapted to be connected to a male thread comprises an exterior surface, a cavity opening away from the exterior surface and defining an interior surface, and a plurality of ribs disposed on the interior surface extending longitudinally away from the exterior surface. The article can be connected to the male thread by threading the cavity onto the male thread. It is a particular advantage that the article of this invention, unlike prior art female threaded articles, can be prepared by conventional simple injection molding techniques not requiring an unscrewing step. In one preferred embodiment, the article is a plunger rod intended to be connected to the male threaded post of a plunger of an associated cartridge-needle unit to form a syringe assembly.

Abstract: A holder for cylindrical ampoules includes a receiving device provided for receiving the cylindrical ampoule and a handle with a bore for receiving a longitudinally displaceable piston rod with an actuating device, the receiving device is integrally formed with the handle and includes a collar with an allround groove in its root.

Abstract: An autodiscardable hypodermic syringe having a preset piston stroke limitation includes an elongated cylinder having an opened end an opposite substantially closed end. A conduit of an external tubular mouth piece for coupling with the needle is connected to the substantially closed end of the cylinder. A piston is slidably received within the cylinder. A rod for sliding the piston is selectively connected to the piston. An end of the rod remote from the piston projects beyond the open end of the cylinder. The piston is selectively connected to the rod through a coupling and uncoupling mechanism. The coupling and uncoupling mechanism includes a narrow body that projects from the internal end of the rod and has a passage coincident with a central axis of the rod. The passage extends from side to side of the narrow body and defines a descending section that in its middle part has a deviation disposed outward of the descending section and of the narrow body.

Abstract: A prefilled syringe is capable of separate storage of different substances before use. It includes a tubular body having an injection needle at one end and a plunger at the other end, and a partition axially slidable in the tubular body. The partition includes a front part and a rear part independent of each other, and as a whole divides the interior space of the tubular body into a front compartment and a rear compartment in a sealing manner for storing mutually different substances. A bypass is disposed generally between the front and rear compartments to introduce the substance in the rear compartment into the front compartment when the partition is slid under pressure provided by the plunger to be adjacent to the bypass to thereby mix the substances immediately prior to injection.

Abstract: A device for transferring liquid between the body of a patient and a syringe includes a syringe barrel defining a bore, a plunger that may slide through the bore to force liquid into or out of the bore, and a pump capable of sliding the plunger. The pump housing positively connects to the bore by sliding a protrusion formed on the exterior of the pump housing into an indentation formed within the interior surface of the bore.

Abstract: A hypodermic syringe and method of filling the syringe with an injection fluid. The syringe includes a fluid chamber for retaining an injection fluid and a plunger assembly for expelling fluid from the chamber. The plunger assembly includes a plunger slidably disposed in the fluid chamber for creating positive pressures to cause ejection of a fluid from the chamber and an actuator coupled to the plunger for movement of the actuator between a first position with the actuator released for movement of the actuator through the fluid chamber relative to the plunger and a second position with the actuator in cooperative engagement with the plunger for driving the plunger to create the positive pressures.

Abstract: A syringe has a tubular body provided at its front end portion with a portion for mounting an injection needle thereon and opens at its rear end portion so as to have a rear end opening. A gasket for sealing the rear end opening of the tubular body is slidably inserted into the tubular body. A plunger rod is detachably coupled with a rear end portion of the gasket through the rear end opening of the tubular body. A male screw is formed at a front end portion of the plunger rod and is circumferentially alternately divided into at least one male screw portion and at least one first recess portion. A female screw is formed on a rear end face of the gasket and is circumferentially alternately divided into at least one female screw portion and at least one second recess portion.

Abstract: The invention relates to a safety valve plug to be used in pre-filled syringes, of the kind comprising a cylindrical hollow body into which a coaxial plunger is displaced, projecting outwardly from one of the bases; while a conical portion is defined at the opposite base, the conical portion receiving the injection needle and being called "plugging cone", the valve plug being snug fit inside said "plugging cone" with its end head bearing on the mouth thereof, said valve plug comprising a substantially cylindrical solid body having a conical end portion and the other portion, defining its head, being cylindrical and of a cross section larger than the rest of the body; the cylindrical body having, following said conical end, two faceted faces extending adjacent the head.

Abstract: A nozzle assembly adapted for an injector, includes a frangible plunger. The plunger has a first driving member and a second driving member connected to the first driving member and spaced apart therefrom by a predetermined gap using a frangible bridge. When a predetermined force is applied to the second driving member, it breaks the frangible bridge and moves the second driving member across the gap. This causes the second driving member to ram into the first driving member driving fluid out of the nozzle. Thereafter, as the second driving member is separated from the first driving member, the first driving member remains stuck in the chamber preventing reuse of the nozzle assembly.

Abstract: Absorbable, segmented copolymers of aliphatic polyesters based on lactone monomers lactide, and p-dioxanone are described. The segmented copolymers exhibit a broad range of properties, especially high strength and long elongations. This unique elastomeric behavior makes the copolymers of the present invention useful in a variety of medical device applications, especially adhesion prevention barriers and hemostatic devices.

Abstract: An angiographic injector has an injector portion which includes a rotating turret for housing two angiographic syringes in readiness for injection. The injector further employs a driving mechanism for connecting with and controlling the movement of a syringe plunger once one of the syringes is in place for injection. Through the use of guide means on each syringe and corresponding alignment means on a pressure jacket, the syringe is alignably and securely mounted within the pressure jacket on the rotating turret. Each syringe plunger is releasably connected to the driving mechanism for an injection operation, and released from the driving mechanism when the injection operation has been completed, such that the driving mechanism can be withdrawn from the syringe relative to the plunger without drawing body fluid of a patient into the syringe. Various types of plunger release mechanisms for this purpose are disclosed.The questions raised in reexamination request No. 90/003,918 filed Aug.