Abstract: An adapter for a medical receptacle having a skirt with an outside diameter and a threaded inside diameter, and a tapered post within the skirt, the adapter includes a proximal end portion having a threaded surface including at least one thread configured to threadingly engage the threaded inside diameter of the skirt, a distal end portion having a surface portion and a cylindrical recess, a conduit positioned between the tapered recess and the cylindrical recess such that the conduit is in fluid communication with both the tapered recess and the cylindrical recess; and a longitudinal axis. The proximal end portion includes a tapered recess defined by a wall, a chamfer, and a seat and the surface portion includes a means for gripping, which in one embodiment may be at least two wings.

Abstract: A one-time use device to deliver preservative-free follicle stimulating hormone (FSH) solution is disclosed. The device includes a needle covered by a sliding needle shield, which covers the needle in all modes of the device. The device can be placed into a ready-to-use position in four or fewer user steps. The device has a knob for setting a desired dose of FSH. The knob includes longitudinally spaced elements respectively corresponding to the lock position and the seven or fewer discrete dosing positions. The device locks after one use and cannot be reused thereafter.

Abstract: The invention relates to an injection device (1) being in one of a passive and active state, triggering of injection being prevented when said device (1) is in its passive state and permitted when said device (1) is in its active state, having: a housing (30, 30a, 30b) receiving a container, the container being in one of a passive state and an active state, movement of the container out of its initial position being prevented when the container is in its passive state, and being permitted when the container is in its active state, and a safety shield (40) coupled with the housing (30) and being movable with respect to the housing along a movement path having a predetermined length, first retaining means (60, 61, 54a) for maintaining the container (20) in its passive state, second retaining means (34a, 81b) for maintaining said device (1) in its passive state, said device (1) being characterized in that it comprises: first deactivating means (50, 53) and second deactivating means (50, 50a) movable coinciden

Abstract: An injection needle assembly is an assembly used by being attached to an injector including an injection barrel filled with medicine and a needle tube, and is provided with a sticking needle tube having a needle tip to be stuck into a skin, a needle holding portion, an engagement portion and a connection portion. The needle holding portion holds the sticking needle tube and a fit tube of the engagement portion is engaged with a needle hub of the injection barrel. The connection portion includes a luminal portion in which there are arranged a proximal end on the opposite side of the needle tip of the sticking needle tube and a needle tip (ejection port) at the needle tube of the injector, and the sticking needle tube and the needle tube communicate with each other in a liquid tight manner.

Abstract: Fluid collection device includes a body having a front end and a back end. The back end is open and/or sized and configured to receive therein a receptacle. A needle holding member is arranged in an area of the front end of the body.

Abstract: A drive ram (26) for use with a medical fluid injector may include a central, longitudinal reference axis (24). First and second gripper members (92) may be pivotally interconnected with a plunger engaging end (266) of the drive ram. Each of the first and second gripper members may be pivotable about a common pivot axis (95) that intersects the reference axis. Each of the gripper members may further include a first end (102) that is remote from the common pivot axis. In some embodiments, the first and second gripper members may be pivotable between a first position and a second position. In the first position, the first ends of the gripper members may be spaced apart by a first distance, while in the second position, they may be spaced apart by a second distance that is greater than the first distance.

Abstract: An applicator tip for use with a fluid applicator includes a base configured for releasable engagement with a fluid applicator at a proximal end of the base. The base includes a chamber defined therein configured for retaining a mixing component therein. One or more penetrable members are disposed within the base to at least partially encloses the chamber to retain the mixing component therein. A shaft extends distally from the base and defines a longitudinal axis. The shaft has a lumen extending therethrough configured for passage of a fluid therethrough. Upon penetration of the penetrable member, fluid from the fluid applicator flows into the chamber such that the fluid and the mixing component form a mixture to be applied.

Abstract: A medical injector (200) includes a medicament container (210) including a main lumen (214) and a reduced-diameter protrusion (220), a needle assembly (230) coupled to the protrusion (220), and a flow control member (250). The medicament container (210) is configured to contain a medicament, such as, for example, a dermal filler. The flow control member (250) is disposed within the protrusion (220) of the medicament container (210), and includes a flow control lumen (254) configured to control a pressure or a flow of the medicament. Thus, the flow control member (250) reduces decoupling forces applied to the needle assembly (230) by the flow of medicament. Alternatively, the flow control member (250) may move from a first position allowing flow from the main lumen (214) to the needle assembly (230) to a second position blocking flow from the medicament container (210) when the needle assembly (230) decouples from the protrusion (220).

Abstract: A retractable needle syringe having a conical frustum tip configured to selectively attach to a Luer device including an inexpensive commonly found Luer filling needle, and also including an interchangeable needle assembly configured to secure to a needle stem positioned within the conical frustum tip. The conical frustum tip advantageously facilitates aspirating a medicant, using a common Luer needle for filling and also prevents the possible unintentional retraction of the needle assembly due to hydraulic pressures encountered when drawing the medicant from a vial and during the handling of the syringe. Moreover, the conical frustum tip advantageously allows the syringe to be conveniently prefilled with a medicant at a pharmacy and capped, then transported to a patient with or without needle assembly as desired. This design is a significant advantage for many healthcare workers involved in the processing and handling of syringes until ultimate delivery of the medicant to a patient.

Abstract: A retractable needle syringe having a segmented retaining ledge at the distal end of the syringe barrel. The retaining ledge has uniformly spaced members configured to enable the retaining ring to break from the needle stem with a reduced plunger engagement force, which provides an improved tactile feeling of the syringe plunger and comfort of use. The segmented retaining ledge also makes it easier to install the needle stem and retaining ring in the barrel distal end, such that it snaps into place therepast with less axial force.

Abstract: A retractable needle syringe, including a needle stem and breakable ring having a plurality of fingers and grooves. These fingers and grooves are configured to mate with a plurality of ribs and grooves in a syringe barrel distal end to provide anti-rotation of the needle stem with respect to a syringe barrel. This anti-rotation feature restricts rotation of the needle stem when attaching or exchanging needles to prevent unintended retraction.

Abstract: A pen needle assembly is provided herein for use with a medical injector containing an injector body and a reservoir sealed by a septum encased in the injector body. The pen needle assembly includes a hub and a needle fixed to the hub. The hub is formed to be telescopingly mounted onto a distal end of the injector body using a track that accommodates a guide key. When mounting the hub of the pen needle assembly onto the injector body, a first portion of the track is configured to receive the guide key and to guide the guide key in a straight line across sufficient distance to permit a proximal end of the needle to fully pierce through the septum, without rotation of the needle. A second portion of the track is configured to permit the pen needle assembly to be turned with the proximal end of the needle being located proximally of the septum.

Abstract: A needle-based medical device including a needle guide and a method for constructing the same are disclosed. The needle-based medical device includes a tube having a first lumen; a needle guide which is dimensioned to be inserted into the lumen of the tube, and a needle. The needle is inserted such that an end is positioned in the needle guide. A glue may also be provided to secure the needle guide to the tube. In one embodiment, the tube may be made of extruded plastic.

Abstract: The present invention is a holder assembly having a holder housing, collar and safety shield. The safety shield is pivotably attached to the collar. The collar is receiving within a recess defined by the annular skirt and needle receiving port of the holder housing. The collar and attached safety shield may thus be rotated about the holder housing and an attached needle assembly, thereby allowing a user to freely position the safety shield during needle insertion and preventing the dislocation of safety shield from the holder housing.

Abstract: The invention refers to a method and an element for biasing a cartridge in a drug delivery device. The element for biasing the cartridge in a cartridge housing of a drug delivery device and an according system comprising the element and the drug delivery device are provided which is a self retained element comprising a first member having a shape that allows passage of a spindle of the drug delivery device. The self retained element biases the cartridge against an inner surface of the cartridge housing. This cartridge could be a removable cartridge.

Abstract: Drug delivery devices having integrated non-luer connectors are described. An exemplary drug delivery device includes a container with a non-luer connector that prevents connection of a standard female luer connector to the container. One or more embodiments pertain to a container with a non-luer connector that prevents the formation of a fluid-tight seal between a standard female luer connector and the container. A non-luer connector for attachment to a container having a non-luer element is also described.

Abstract: A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first portion that defines a passageway substantially parallel to a longitudinal axis of the needle mount and a second portion substantially perpendicular to the axis. The needle hub and mount provide a method wherein a needle assembly may be mounted on an injection device without completely rotating the needle hub relative to the needle mount.

Abstract: A needle assembly (2) for a drug delivery device (1) comprises a needle seal (3), a needle retainer (4) and a needle (5). The needle retainer (4) secures the needle (5) against displacement with respect to said needle retainer (4) when a dose of drug is being delivered. The needle seal (3) is configured to push onto the needle retainer (4) after delivering the dose of the drug, thereby unlocking the needle (5) from the needle retainer (4).

Abstract: A one piece molded vacuum tube holder is fitted with a one piece molded needle hub assembly. A needle protection device is further rotatably mounted to the neck of the one piece vacuum tube holder. One portion of a locking mechanism is provided at the neck of the one piece vacuum tube holder and a second portion of the locking mechanism is provided at the needle hub of the needle hub assembly, so that when the needle hub assembly is press fit to the vacuum tube holder, the two portions of the locking mechanism will coact to fixedly retain the needle hub assembly within the vacuum tube holder. The one piece vacuum tube holder is configured to have an elongate needle cover integrally extending from its neck. A tamper evident notched joint is provided at the junction where the needle cover is connected to the neck.

Abstract: In one aspect, a pen needle assembly is provided herein which includes a hub, and a needle fixed to the hub, the needle having proximal and distal ends with a lumen extending therebetween. The needle extends distally from the hub to define an exposed length between the distal end of the needle and the hub in the range of about 5.0 to 9.0 mm. The hub defines a post formed about the needle, the post having a distally-facing first skin engaging surface. The exposed length of the needle extends distally from the first skin engaging surface. The hub also defines a distally-facing second skin engaging surface which at least partially circumscribes the first skin engaging surface. The second skin engaging surface being located proximally of the first skin engaging surface. Advantageously, with the subject invention, a pen needle assembly is provided having two skin engaging surfaces which provide stability in achieving subcutaneous injections.

Abstract: A seal member is configured to seal a chamber of a drug delivery device which is suitable to contain a drug, wherein the seal member comprises a diaphragm.

Abstract: A needle assembly adapted for fluid communication with a vial containing a substance to be delivered to a subject, the needle assembly including a needle held in a needle holder, the needle holder confined to move in a housing, and an activation mechanism for activating delivery of the substance through the needle, the activation mechanism including a safety latch that initially impedes movement of the needle holder, wherein when the safety latch is placed on the subject, the safety latch moves to a position that permits moving the needle holder to cause the needle to protrude outwards of the housing to pierce the subject to allow administration of the substance to the subject.

Abstract: A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first portion that defines a passageway substantially parallel to a longitudinal axis of the needle mount and a second portion substantially perpendicular to the axis. The needle hub and mount provide a method wherein a needle assembly may be mounted on an injection device without completely rotating the needle hub relative to the needle mount.

Abstract: A syringe adapter with a ball-typed valve has a base, a dosing tube mounted around the base and a resilient valve mounted in the base and the dosing tube. The base has a guiding groove and an inner liquid channel communicating with each other, as well as an exhaust channel. Liquid medicine injected into the syringe adapter flows through the guiding groove and causes the inner liquid channel to be injected into a patient's body. The liquid medicine remaining in the split is cleaned when cleaning fluid is injected to clean the syringe adapter. Air in the syringe adapter flows out through the exhaust channel and is not injected into the patient's body, so the patient is free from pain. Furthermore, elements and assembling processes of the syringe adapter are simplified and manufacturing cost of the syringe adapter is lowered.

Abstract: A flow delivery system including a syringe that includes an outer plastic shell, a leur and a plunger; and a needle and/or a catheter that embodies a hub and a cannula which delivers a solution of a material. Various structures are included to provide locking engagements, torque sensitive connections, sufficient interfacing between components and visual conformation of connectors. The syringe assembly can also include an approach to a filter. Moreover, an approach to sterilization is provided.

Abstract: An apparatus is disclosed for storing and changing needles for a medicament delivery device having a medicament container, including a fixed mount for connecting the apparatus with the medicament delivery device, a needle holder displaceable along a circuitous path and connecting a plurality of needles displaceably disposed thereon, and a guide member for guiding displacement of the needle holder, the guide member being disposed about the fixed mount. The apparatus also includes a user interface rotatably disposed about the fixed mount and having at least one internal engaging structure for displacing the needle holder along the circuitous path.

Abstract: A flip-open multi-pack assembly is provided which can contain a plurality of new pen needles, such as through the provision of a rectangular or tube-shaped shaped, hinged shell housing, wherein new pen needles can be stored in a plurality of user accessible openings each having a sterility barrier formed, for example, by covers that cover the non-patient end of the openings in which the new pen needles are contained. Used pen needles can be returned and stored in openings accessible by rotatably opening the shell housing. One or more of the openings within first and second opposite ends of the housing shell can be provided with a slidable internal holder within the device and are configured to releasably secure the inner shield of the new pen needle, and to then be pulled forward when the new pen needle is removed and lock at a forward position, and thereby create an interior space, accessible from an opposite end when the hinged housing is opened, for a used pen needle to be inserted and stored.

Abstract: The syringe is intended for one-off use and has a syringe barrel (1), a barrel stopper (12) which can be displaced in the syringe barrel (1) by means of a plunger rod (11) and a needle unit (25) accommodated in the syringe barrel (1). The plunger rod (11) and the needle unit (25) are connected to one another by coupling means (20, 40) in order to retract the needle unit (25) into the syringe barrel (1) after the injection. As proposed by the invention, the needle unit (25) comprises a needle holder (26) made from plastic surrounding an injection needle (27) made from stainless steel along part of its length, which is closed off from an interior of the syringe barrel (1) containing an injection solution (50) by means of a seal insert (36) made from pharmaceutical rubber through the injection needle (27) extends from the rear end. As a result of this feature, an injection solution (50) contained in the syringe is in contact exclusively with permitted materials and the syringe can therefore be stored pre-filled.

Abstract: A needle magazine for holding a plurality of injection needles (50) is described. The needle magazine comprises a first opening adapted to receive the device fluid access portion (120) of a medical delivery device. Each needle (50) is selectively moveable from a respective storage position not aligned with said first opening into a needle mounting position aligned with said first opening. The needle magazine further comprises needle positioning means (41). configured to alter the mutual position between a needle selected from said plurality of needles (50) relative to a neighbour needle when said selected needle moves from its storage position to the needle mounting position.

Abstract: A self-destroying disposable syringe includes a barrel which includes a hub disposed on the front end of the barrel, a flange is disposed on the inner wall of the hub; a needle base which connects to the hub of the barrel, and includes a connecting portion, a containing portion disposed on the outer side of the connecting portion, and a self-destroying ring disposed on the back end of the needle base and connected to the connecting portion through one or more ribs; when the needle base has connected to the barrel, the connecting portion and the self-destroying ring are located in the inside of the hub of the barrel, and the self-destroying ring matches the flange each other; a plunger which is movably inserted into the barrel and includes a bar body, a pushing stem connected to the back end of the bar body, a pushing dish connected to the front end of the bar body, a cone with one end fixed to the pushing disc, and a puncturing portion fixed to the other end of the cone; and a piston which is connected to the

Abstract: A safety syringe adapted consists of an outer casing that supports a conventional hypodermic needle and an inner casing which supports a blunt cannula that is disposed inside the inner lumen of the hypodermic needle. The inner casing is keyed to the outer casing by one or more pins that engage helical tracks formed along the inner surface of the outer casing. Rotation of the inner casing relative to the outer casing advances the inner casing so that the blunt cannula is moved from a retracted position within the needle to an extended position in which the blunt end of the cannula extends beyond the tip of the needle.

Abstract: The invention relates to a device for injecting liquids, more particularly liquid medicaments or hormone preparations, for example insulin, said device comprising a housing part in or on which a cartridge containing the liquid can be arranged, wherein the housing part or the cartridge has a needle seat designed for releasable attachment of a needle holder carrying a needle, and wherein the cartridge, upon release of the needle holder from the needle seat, is held fixed in position in or on the housing part. In order to release the needle holder, a release element is provided that engages on the needle holder and that can be activated by an actuating element.

Abstract: An injection system applicable to off-the-shelf syringes having a microneedle hub may reduce dead space and isolate the drug fluid from the microneedle chip to avoid compatibility issues. An insert may be disposed inside a male luer fitting and extend so that it is also disposed inside the female luer fitting using an insert. A septum may isolate the drug fluid from the microneedle chip in the hub prior to activation and the septum may, after activation, seal the triangular space in the hub to prevent leakage of fluid back to the syringe.

Abstract: A needle-based medical device including a needle guide and a method for constructing the same are disclosed. The needle-based medical device includes a tube having a first lumen; a needle guide which is dimensioned to be inserted into the lumen of the tube, and a needle. The needle is inserted such that an end is positioned in the needle guide. A glue may also be provided to secure the needle guide to the tube. In one embodiment, the tube may be made of extruded plastic.

Abstract: Syringe having a snap-fit mechanism for attaching a needle hub to a syringe barrel in a snap-fit relationship and packaged medical device comprising a syringe with a snap-fit mechanism and a needle hub are provided. An exemplary syringe includes a barrel with a collar and a rotatable arm which allows connection of a needle hub to the barrel in a snap-fit relationship. Additional features of the collar and rotatable arm may also permit disconnection of the needle hub from the barrel without the use of relative rotation of the needle hub and barrel. In a specific configuration, the syringe utilizes a torsional snap-fit element to connect the needle hub to the barrel in a snap-fit rotation. In a more specific configuration, the syringe utilizes a collar with differing interior surfaces which permit snap-fit assembly and disassembly of the needle and the barrel.

Abstract: A medical injector is provided herein having a body and a needle mounting surface movable relative to the body, the needle mounting surface having features for mounting a needle thereto. In an initial state, the needle mounting surface is disposed within the body with no needle mounted thereto. With relative movement between the body and the needle mounting surface, the needle mounting surface is urged out of the body. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered.

Abstract: The present invention relates to a method of producing syringes. Said method comprises fixing a needle to a syringe body by use of an adhesive followed by subjecting the syringes thus obtained to heat treatment. The invention further relates to a method of reducing leachables and/or extractables in prefilled syringes, said method comprising heat treating pre-fabricated syringes at a temperature of at least 40° C. before filling.

Abstract: A needle mounting assembly for mounting a pen needle in fluid communication with a medication cartridge. A collet defines an opening in which is slidably fittable the outlet end of the cartridge. The collet is shiftable relative to the cartridge outlet end. When the collet is disposed in a first axial position, a plurality of fingers of the collet extend forward of the cartridge outlet end and are disposed in a first radial arrangement in which a needle hub of the pen needle can be freely axially placed onto and freely axially removed from the plurality of fingers. When the collet is moved to a second position, the plurality of fingers are shifted by engagement with the cartridge outlet end to operationally secure the needle hub. When the collet is moved back to the first position, the plurality of fingers shift back for free axial removal of the needle hub from the mounting assembly.

Abstract: A needle guide system comprising a needle guide including at least one wall defining an internal cavity and an outside of the needle guide. A lock is connected to the needle guide. The lock is movable between a first and a second position. A needle is disposed in the internal cavity of the needle guide, the needle having a long axis and a tip. The needle is movable along the long axis with respect to the needle guide when the lock is in the first position and the needle is locked to the needle guide and the tip extends beyond the wall of the needle guide when the lock is in the second position. Visual indicia on the lock may indicate whether the lock is in the first or the second position.

Abstract: A needle tip of a needle tube stuck in the skin is caused to be reliably positioned in the skin upper layer part and the injected drug is caused not to leak to the outside of the body. An injection needle 1 is provided with a needle tube 2 of 26-33 G having a needle tip, a hub 3 that holds the needle tube 2, and an adjustment unit 4 provided around the needle tube 2 and having a needle-protruding surface 4b through which the needle tip of the needle tube 2 protrudes. And, the needle-protruding surface 4b of the adjustment unit 4 is formed such that the distance S from the circumferential edge to the circumferential surface of the needle tube 2 is in the range of 0.3-1.4 mm.

Abstract: A hypodermic needle having a hub with a distal surface extending at an obtuse angle from a short needle, and a bevel approximately parallel to the distal surface.

Abstract: The present invention inhibits the occurrence of the foreign matters attributable to an adhesive for bonding an injection needle to a needle-base member so as to enhance the yield of a syringe when producing the same. A front-assembly (3) additionally provided at a leading end of an injection cylinder (2) comprises an injection needle (4), a needle-base member (5), a connection hub (6) and a protector cap (7). The injection needle (4) and the needle-base member (5) are fixed to each other with an epoxy adhesive (19). This adhesive (19) contains denatured aliphatic epoxy resin in the amount set to about 10 to about 25 wt % and its viscosity is set to about 20000 to about 40000 mPa·s. This adhesive (19) is heated at a temperature of at least 130 degrees C. for about 20 minutes to cure it. After the front-assembly (3) and the injection cylinder (2) have been sterilized with vapor, the connection hub (6) has a connection portion (17) external fitted and secured to the leading end of the injection cylinder (2).

Abstract: A drug delivery device is provided herein which includes a tubular body having a proximal end and a distal end, the tubular body defining an opening at or in proximity to the distal end, the opening defining an inner diameter. A drug cartridge is also provided having a proximal end, a distal end and a barrel portion disposed therebetween. The distal end of the drug cartridge is larger in diameter than the inner diameter of the opening. The drug cartridge is inserted into the tubular body to a use position by first inserting the proximal end of the drug cartridge into the opening. The distal end of the drug cartridge limits insertion of the drug cartridge into the tubular body due to the interengagement of the distal end of the drug cartridge and the tubular body. With the drug cartridge being in the use position, the distal end of the drug cartridge is located at least partially externally of the tubular body.

Abstract: A connector (900) for fluid conduit includes a connector body (901) having a lumen (902) passing along a longitudinal axis (903), and a luer access port (800) extending distally along a transverse axis (905). The luer access port (800) is made from a thermoplastic elastomer (500) having a domed interior portion (501) and a stair-stepped perimeter (502) that is coupled to a cylindrical wall (600). The thermoplastic elastomer (500) and cylindrical wall (600) can be integrally coupled in an insert molding process.

Abstract: An injection needle assembly includes a needle having a needle point to puncture skin, a needle hub including a first member which holds the needle, and a second member in which a discharge part of a syringe is to be fitted, and an elastic member disposed inside the second member to make liquid-tight close contact with the inner surface of the second member, with the elastic member having an insertion hole in which the needle tube is inserted.

Abstract: A device for at least one of storing, installing and removing pen needles. The device includes a body configured to store at least one pen needle. A first end of the body is configured to install a pen needle on an injection device. A second end of the body is configured to remove a pen needle from the injection device. The invention also provides for a method of installing and/or removing a pen needle from an injection device using the device. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.

Abstract: Medical device assemblies having a connection mechanism for securely connecting a hub to fluid storage containers in a luer slip relationship are described. An exemplary medical device includes a hub forming a cavity, a second indicating element disposed within the cavity that engages the hub. Additional features of the medical device include a second indicating element contoured to form a line contact with the hub. In a specific configuration, the hub includes a first indicating element attached to the hub and extending proximally into the cavity having a protrusion. In a more specific configuration, the medical device includes a fluid storage container that has an indication system for visually indicating optimal fluid-tight engagement of the hub and the fluid storage container.

Abstract: According to the invention, the accessory (1) comprises a body (15) of roughly semi-tubular shape, first means of holding the syringe comprising a distal transverse wall (20) connected to one end of said body (15), and pierced with a hole (22) for the passage of the needle (7) through it, and second means of holding the syringe comprising a bearing zone (61) against which the proximal flange (10) or the lateral lugs that the syringe body (5) comprises is or are intended to bear so as to provide support for the user's fingers; the distance between said distal transverse wall (20) and said bearing zone (61) is such that the adapter (8) connecting the needle (7) to the syringe body (5) is kept bearing against said distal transverse wall (20) when said flange (10) or said lateral lugs are bearing against said bearing zone (61).

Abstract: A method and system for biasing a cartridge in a drug delivery device. An element for biasing a cartridge in a cartridge housing of a drug delivery device is provided. This non-plastic element does not comprise a coil spring. A self retained element for providing a spring bias to a cartridge in a cartridge holder of a drug delivery device comprises a first member having a shape that allows passage of a spindle of the drug delivery device. A portion of the first member is self retained by an internal surface of the drug delivery device. The self retained element biases the cartridge against an inner surface of the cartridge holder. This cartridge could be a removable cartridge.

Abstract: A syringe hub comprises a hub body which is engagable with a syringe body, a needle held by the hub body, a movable bung element within a flow passage of the hub body, and at least one fixed engagement element which extends laterally to the longitudinal extent of the flow passage and which is non-releasably engagable with the bung element to block a flow path defined by the hub body and the needle. The movable bung element including a cap element which extends laterally to the longitudinal extent of the flow passage and a splayable engagement element which extends from the cap element. The splayable engagement element includes a plurality of legs. A syringe which has a syringe body and the said syringe hub is also provided.