Having Means For Metering Liquid Flow To Eye Patents (Class 604/298)
  • Patent number: 10537468
    Abstract: Systems and methods for medication management are provided. Some embodiments provide for a portable medication management and monitoring system for eye drop instillation in ocular chronic conditions. At least one embodiment includes a device having one or more of the following elements: (a) a jacket that goes around an eye drop bottle; (b) tactile sensors to detect the user's fingers and generate data to activate the system; (c) motion sensors to detect the motion of the medication bottle when it is grabbed and moved by the user; (d) a wireless communication module to send and receive data to a computer and portable communication devices; and/or (e) a compartment for holding the electronic components.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: January 21, 2020
    Assignee: KALI CARE, INC.
    Inventor: Sina Fateh
  • Patent number: 10441214
    Abstract: A method and apparatus for monitoring and/or managing adherence to a medication regimen that involves use of a sensor. Dispensing medicine from a container commonly involves pressure being applied to the container, which results in expansion of the container. In some embodiments, pressure is applied by a user through an aperture of the apparatus. In some embodiments, a processor monitors pressure sensor data from a pressure sensor that is physically coupled to the container and arranged such that activation of the pressure sensor indicates the container has expanded in response to the user applying pressure. A processor analyzes the pressure sensor data to determine whether medicine has been dispensed from the container. A computer system can compare the dispensed medication to a planned medication regimen to determine a state of compliance with the medication regimen.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: October 15, 2019
    Assignee: KALI CARE, INC.
    Inventor: Sina Fateh
  • Patent number: 10363668
    Abstract: Provided are systems and methods for the post-treatment of dry adhesive microstructures. The microstructures may be post-treated to comprise mushroom-like flaps at their tips to interface with the contact surface. In some aspects, a change in material composition of the microstructures in a dry adhesive may affect mechanical properties to enhance or diminish overall adhesive performance. For example, conductive additives can be added to the material to improve adhesive performance. In other aspects, microstructures comprising conductive material may allow for pre-load engagement sensing systems to be integrated into the microstructures.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: July 30, 2019
    Assignee: ONROBOT LOS ANGELES INC.
    Inventors: Mohammad Dadkhah Tehrani, Nicholas Wettels
  • Patent number: 10366207
    Abstract: A method and apparatus for monitoring and/or managing adherence to a medication regimen that involves use of a sensor. Dispensing medicine from a container commonly involves motion of the container, which can be a distinctive motion. In some embodiments, a processor monitors motion sensor data from a motion sensor that is physically coupled to the container, such that the motion sensor and the container move in unison. A processor analyzes the sensor data to determine physical movement of the container. When the determined movement matches the distinctive motion of medicine being dispensed, the processor can determine that medicine has been dispensed. A computer system can compare the dispensed medication to a planned medication regimen to determine a state of compliance to the medication regimen. The computer system can take an action based on the compliance state, such as sending a message indicating the compliance state to a medical professional.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: July 30, 2019
    Assignee: KALI CARE, INC.
    Inventor: Sina Fateh
  • Patent number: 10342109
    Abstract: A method of controlling an excitation laser includes detecting, at a droplet generator, a first signal of radiation scattered by a given target droplet irradiated by a first radiation source at a first position. The method of controlling the excitation laser further includes detecting, at the droplet generator, a second signal of radiation scattered by the given target droplet irradiated by a second radiation source at a second position a fixed distance away from the first position, and determining a speed of the given target droplet based on a time lag between the detecting of the first signal and the detecting of the second signal. The method further includes controlling a trigger time for triggering an excitation pulse for heating the given target droplet based on the determined speed of the given target droplet.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: July 2, 2019
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Wei-Chih Lai, Han-Lung Chang, Bo-Tsun Liu, Li-Jui Chen, Po-Chung Cheng
  • Patent number: 10300088
    Abstract: The invention relates to a method for producing eye drops, the thus obtained eye drops and to a kit which comprises the eye drops.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: May 28, 2019
    Assignee: Herr Marc Schrott, Central Apotheke
    Inventors: Marc Schrott, Andrea Jochheim-Richter
  • Patent number: 10152867
    Abstract: Systems and methods for medication management are provided. Some embodiments provide for a portable medication management and monitoring system for eye drop instillation in ocular chronic conditions. At least one embodiment includes a device having one or more of the following elements: (a) a jacket that goes around an eye drop bottle; (b) tactile sensors to detect the user's fingers and generate data to activate the system; (c) motion sensors to detect the motion of the medication bottle when it is grabbed and moved by the user; (d) a wireless communication module to send and receive data to a computer and portable communication devices; and/or (e) a compartment for holding the electronic components.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 11, 2018
    Assignee: KALI CARE, INC.
    Inventor: Sina Fateh
  • Patent number: 9585908
    Abstract: Combustion reactions release pollutant gases that associate with ocular fluids and tissues which can have an acute ocular impact. The chronic irritation and chemical effects of these gases also promote ocular aging over the lifespan. Instantaneous pollutant effects can be reduced at the time of eye exposure by using an eyewash (collyrium) composition comprising hydroxocobalamin and/or hydroxo(aquo)cobalamin. Such compositions minimize pollutant gas reactions with ocular tissues by (1) deactivating the gases; and (2) expediting their removal from the eye by, for example, aqueous rinsing and dilution.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: March 7, 2017
    Assignee: Chromaceutical Advanced Technologies, Inc.
    Inventors: Robert A. Beck, Robert A. Mateer, Jr.
  • Publication number: 20150139973
    Abstract: The present invention relates to an ophthalmological vehicle system for the permeation and/or for the active substance transport of ophthalmological active substances through the cornea and/or the sclera of the eye of mammals. This vehicle system assists the transport of the active substances through the cornea and/or the sclerotic tissue of the eye. The vehicle system is suitable for the prophylaxis and/or treatment of diseases of the front and/or back portion of the eye. Likewise, the present invention relates to an ophthalmological kit, comprising a special ophthalmological composition and also, as separate formulation, an ophthalmological active substance.
    Type: Application
    Filed: May 14, 2013
    Publication date: May 21, 2015
    Inventors: Ute Steinfeld, Frank Holzer, Hyeck Hee Lee, Markus Mahler
  • Publication number: 20150112286
    Abstract: Device for packaging and dispensing drops of a substance for ophthalmic use, generally fluid, semi-fluid or in suspension, emulsion or oily solution, comprising a dispensing accessory (7) with a first valve (5) made of an elastomer material that allows the substance to pass through when the dispensing accessory (7) is stressed, without allowing outside air to pass through in the opposite direction when the dispensing accessory (7) is relaxed, characterized in that the first valve (5) is covered by a layer of Parylene.
    Type: Application
    Filed: February 8, 2013
    Publication date: April 23, 2015
    Applicant: HORUS PHARMA
    Inventors: Martine Claret, Pierre Roy
  • Patent number: 9011353
    Abstract: Apparatuses, systems, and methods for applying reduced pressure to a tissue site on a foot are provided. An apparatus may include an insole and a tissue contacting surface covering at least a portion of the insole. At least one portion of the tissue contacting surface is removable to form a void. The apparatus may also include a reduced-pressure interface for receiving reduced pressure from a reduced-pressure source, and at least one flow channel fluidly coupled to the reduced-pressure interface and the void.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: April 21, 2015
    Assignee: KCI Licensing, Inc.
    Inventors: Ian James Hardman, Colin John Hall
  • Patent number: 8998861
    Abstract: Systems and methods for medication management are provided. Some embodiments provide for a portable medication management and monitoring system for eye drop instillation in ocular chronic conditions. At least one embodiment includes a device having one or more of the following elements: (a) a jacket that goes around an eye drop bottle; (b) tactile sensors to detect the user's fingers and generate data to activate the system; (c) motion sensors to detect the motion of the medication bottle when it is grabbed and moved by the user; (d) a wireless communication module to send and receive data to a computer and portable communication devices; and/or (e) a compartment for holding the electronic components.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: April 7, 2015
    Assignee: Rxense, Inc.
    Inventor: Sina Fateh
  • Patent number: 8986266
    Abstract: A device for dispensing liquid including a liquid reservoir which can be deformed so as to dispense liquid by pressing on the reservoir, a liquid-dispensing end piece fitted on the reservoir, a channel for the passage of liquid, a channel for the passage of air from the outside to the inside of the reservoir, the channel for the passage of air being closed off by a member made of an air-permeable polymeric material, this material being non-porous, the member being called the air-permeable member.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: March 24, 2015
    Assignee: Nemera la Verpillière S.A.S.
    Inventors: Gaetan Painchaud, Guillaume Grevin, Xavier Julia, Thierry Decock, Thierry Rimlinger
  • Patent number: 8979809
    Abstract: A method for optimizing pupil size in individuals suffering from excessive pupillary dilation in dim light as well as through medication is disclosed. Alpha 1 antagonist is applied in an eye drop formulation to the eye, resulting in reduced pupil size in dim light, but less reduction in pupil size in bright light.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: March 17, 2015
    Assignee: Ocularis Pharma, LLC
    Inventor: Gerald Horn
  • Publication number: 20150038925
    Abstract: A nozzle is provided herein for ophthalmic dispensers which is configured to accommodate microdosing. The nozzle includes a converging pathway. Preferably, the pathway converges so as to impart momentum to liquid passing therethrough through an increase of velocity. A tapered portion may be provided flared openly from the inlet to best accept liquid flow thereinto and provide a funneling effect into the flowpath. Preferably, the flowpath terminates at an outlet which is internally un-radiused and circumscribed by a chamfered surface.
    Type: Application
    Filed: March 13, 2013
    Publication date: February 5, 2015
    Inventors: Gene Parunak, Robert C. Martineau, Aaron J. Munsinger
  • Publication number: 20150018781
    Abstract: Systems, devices, and methods are provided for delivering a therapeutic substance to the eye of a subject with an automated apparatus. The apparatus can resemble a pair of eyeglasses that can assist in the alignment of a substance ejecting nozzle and energy sensor with the eye. The apparatus can eject the therapeutic substance and immediate response to the detection of a blink of the user's eye. The therapeutic substance can be ejected in a number of different forms including as a single droplet containing the entire prescribed dosage.
    Type: Application
    Filed: April 9, 2014
    Publication date: January 15, 2015
    Applicants: CALIFORNIA INSTITUTE OF TECHNOLOGY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Derek Rinderknect, Michael J. Geske, Morteza Gharib, Daniel M. Schwartz
  • Publication number: 20150005721
    Abstract: This invention provides for a method and a device for dispensing precise quantities of a predetermined volume of medicaments or other liquids onto the eye, via one or more discrete drop(s) generated by the device in a practical and innoxious way to users.
    Type: Application
    Filed: October 1, 2012
    Publication date: January 1, 2015
    Applicant: Johnson & Johson Vision Care, Inc.
    Inventors: Leslie A. Voss, Catie A. Morley, Gary S. Hall
  • Publication number: 20140336596
    Abstract: Dispenser for dispensing pharmaceutical liquid having a housing, a liquid reservoir, arranged within the housing, an exit opening, through which liquid is discharged into a surrounding atmosphere, an outlet channel connecting the liquid reservoir to the exit opening and having an outlet valve, openable in a pressure-dependent manner or actuatable manually, arranged in the outlet channel. With the valve closed, the outlet channel is subdivided into a first portion upstream of the outlet valve and a second portion downstream of the outlet valve. The housing is of antibacterial design in the region of surfaces which are intended to come into contact with the liquid, wherein it is exclusively surfaces in the region of the second portion and/or of an outer surface of the housing which have this antibacterial design.
    Type: Application
    Filed: November 8, 2012
    Publication date: November 13, 2014
    Inventor: Matthias Wochele
  • Patent number: 8821440
    Abstract: An injection device has a dispensing chamber housing, a plunger, and a temperature control device. The dispensing chamber housing has a first part and a second part. The first part is thermally coupled to a needle. The second part is thermally coupled to the first part. The second part has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with an inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The temperature control device at least partially surrounds the dispensing chamber housing and is capable of altering a temperature of the substance in the dispensing chamber. The second part has a greater thermal coefficient than the first part.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: September 2, 2014
    Assignee: Alcon Research, Ltd.
    Inventors: Robert Sanchez, James Foster, Cesario Dos Santos
  • Publication number: 20140213989
    Abstract: The current invention discloses a fluid dispenser especially suitable for ophthalmic treatments and delivering of ophthalmic agents such as eye drops. The fluid dispenser incorporates a tube made from compliant materials as the key dosing component. A first point and a second point on the tube may be acted upon by folding the tube or by external elements, making the segment between the first point and the second point a squeezing section that houses a dosing chamber. The squeezing section may be pressed by an anvil or other structures, pressurizing the fluid contained in the dosing chamber so that once the tube is released on one point, the fluid in the dosing chamber is discharged. With each dosing process, a single dose of the fluid is discharged. In addition, the fluid dispenser is capable of delivering a series of doses of the fluid by repeating the dosing process.
    Type: Application
    Filed: May 18, 2012
    Publication date: July 31, 2014
    Inventor: Nigel Kelly
  • Publication number: 20140187969
    Abstract: A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.
    Type: Application
    Filed: March 7, 2014
    Publication date: July 3, 2014
    Applicant: Corinthian Ophthalmic, Inc.
    Inventors: Charles Eric HUNTER, Bernard L. BALLOU, JR., Jurgen Klaus VOLLRATH, Arthur H. TEW, Joshua Richard BROWN, James Thornhill LEATH, Nathan R. FAULKS, Bradley G. JOHNSON, J. Sid CLEMENTS, Phillip E. RUSSELL, John H. HEBRANK, Tsontcho INACHULEV, Mark PACKER, Troy ELLIOTT, Walter M. FIERSON, Thomas J. LINDNER
  • Patent number: 8757436
    Abstract: An ophthalmic dispenser and method of filling and dispensing fluid stored therein. The dispenser includes a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: June 24, 2014
    Assignee: Medical Instill Technologies, Inc.
    Inventors: Daniel Py, Norbert M. Assion, Julian V. Chan, Joseph M. Ting
  • Patent number: 8733935
    Abstract: The disclosure relates to medical databases, remote monitoring, diagnosis and treatment systems and methods. In one particular embodiment, a system for remote monitoring, diagnosis, or treatment of eye conditions, disorders and diseases is provided. This method generally includes administering a stream of droplets to the eye of a subject from an ejector device, and storing data related to the administration in a memory of the ejector device. The data may then be monitored and analyzed.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: May 27, 2014
    Assignee: Corinthian Ophthalmic, Inc.
    Inventors: Bernard L. Ballou, Jr., Jurgen Klaus Vollrath, Kelly C. Sparks, Joshua Richard Brown, Mark Packer, Charles Eric Hunter, Troy Elliott, John H. Hebrank
  • Patent number: 8734408
    Abstract: An eye drop bottle holder with resilient legs includes an inverted U-shaped member made from resilient injection molded plastic. The top portion of the inverted U-shaped member includes an eye drop bottle holder. The right and left leg of the U-shape each terminate in an outwardly disposed J-shape covered by a soft rubber-like pad. The user can attach an eye drop bottle to the inverted U-shaped member so that the dispensing tip of the bottle is in close proximity the user's eye. The user can cause his or her eye lid to remain open by squeezing the right and left legs together, then placing the pads on the upper and lower eye orbit, then releasing the legs causing the flesh of the user's eyelids to be spread apart. In a preferred embodiment, an electro-mechanical assembly can automatically press on the side wall of the bottle to cause a predetermined amount of solution to be dispensed. An LED light flashes (is either activated or deactivated) to show the user that a dispensing event has taken place.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: May 27, 2014
    Inventor: Alvin J. Marx
  • Patent number: 8684980
    Abstract: A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: April 1, 2014
    Assignee: Corinthian Ophthalmic, Inc.
    Inventors: Charles Eric Hunter, Bernard L. Ballou, Jr., Jurgen Klaus Vollrath, Arthur H. Tew, Joshua Richard Brown, James Thornhill Leath, Nathan R. Faulks, Bradley G. Johnson, J. Sid Clements, Phillip E. Russell, John H. Hebrank, Tsontcho Inachulev, Mark Packer, Troy Elliott, Walter M. Fierson, Thomas J. Lindner
  • Publication number: 20140088524
    Abstract: An eyedrop delivery system for the automated dispensing of eyedrop solution from bottles and ampoules. The system includes a battery and electronic control circuitry. A sprocket drive motor directs the advancement of a loop cartridge band containing eyedrop solution ampoules, moving each one at a time into position for dispensing. A motor rotates a cam to strike a push rod to compress each ampoule. The system includes an eyelid retracting leg assembly. The cartridge automatically advances the next full ampoule into position for dispensing and pushes the ampoule tip aside. The system helps assure that: (1) a known number of drops are dispensed; (2) the dispensed eyedrop(s) fall on the eyeball (by providing eyelid retracting legs to keep the eye open); and (3) the eyedrop(s) landing on the surface of the eye are confirmed using a drop dispensing sensor pair and a surface of the eye sensor pair.
    Type: Application
    Filed: September 11, 2013
    Publication date: March 27, 2014
    Inventor: Alvin J. Marx
  • Patent number: 8579856
    Abstract: The delivery systems of the present disclosure are configurable to administer either single-dose or multiple-doses of one or more substances to a user, for example to the eye, nose, mouth, ear or rectum of the user. The precise and repeatable dosing features of the presently disclosed delivery systems overcome many of the disadvantages associated with known methods for dispensing substances to, for example, the eye of a user. The delivery systems administer precise doses of a substance to a precise location from unit dosage forms that may be single-dose or multiple-dose unit dosage forms, which may be externally or internally pierced.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: November 12, 2013
    Assignee: Mystic Pharmaceuticals, Inc.
    Inventors: Timothy R. Sullivan, Jeffrey Nelson
  • Publication number: 20130274693
    Abstract: Improved liquid dispenser devices configured to deliver liquid compositions to a user's eye are described, as well as methods for making and using such devices.
    Type: Application
    Filed: October 11, 2012
    Publication date: October 17, 2013
    Inventors: Mark R. NOWAKOWSKI, Vito Frank ASARO, Craig R. NOWAKOWSKI
  • Publication number: 20130261569
    Abstract: The present invention is directed to a pulsatile ophthalmic peri-corneal drug delivery device. The device includes an annular body and a mechanism for releasing multiple separate and distinct doses of a therapeutic composition over an extended period of time.
    Type: Application
    Filed: May 20, 2013
    Publication date: October 3, 2013
    Inventors: Alan L. Weiner, Bhagwati P. Kabra
  • Patent number: 8545463
    Abstract: A reservoir assembly for use in an ophthalmic fluid delivery device adapted to deliver an ophthalmic fluid in the form of a mist to an ocular region of a patient is provided, wherein the device has a lumen-defining component configured to deliver the fluid from the reservoir assembly. The reservoir assembly includes a reservoir defining an aperture and a cavity in fluid flow communication with the aperture, a fluid contained in the cavity of the reservoir, and a gasket traversing the aperture. The gasket defines a passage configured to receive a portion of the lumen-defining component and to permit the flow of the fluid from the cavity and through the aperture when the portion of the lumen-defining component is inserted through the passage. The gasket is also configured to substantially prevent the flow of the fluid from the cavity and through the aperture when the portion of the lumen-defining component is not inserted through the passage.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: October 1, 2013
    Assignee: Optimyst Systems Inc.
    Inventors: James F. Collins, Jr., Michael Joseph Jobin
  • Publication number: 20130245579
    Abstract: A medicated module containing a second medicament is configured for removable attachment to ophthalmic drug delivery device containing a first medicament such that a single activation of the ophthalmic drug delivery will deliver both medicaments to the user.
    Type: Application
    Filed: November 28, 2011
    Publication date: September 19, 2013
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Garen Kouyoumjian, Malcolm Stanley Boyd
  • Patent number: 8496635
    Abstract: A container includes a nozzle having rubber elasticity in a constriction part, and a lever for nipping the nozzle indirectly. The nozzle has a storage part, a base, and a valve. The storage part is provided in the constriction part, and is intercepted with the main body by contacting inner walls at the communicating part when the nozzle is nipped and flattened by the lever. The valve is opened when the internal pressure of the storage part exceeds predetermined pressure while operated state and spouts liquid in the storage part. The constriction part expands by being nipped with the lever until the internal pressure of the storage part reaches to predetermined pressure. Liquid in the storage part is jetted since the constriction part shrinks by the rubber elasticity when the valve is released.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: July 30, 2013
    Inventor: Ryu Katayama
  • Publication number: 20130190704
    Abstract: A device has a first part with a valve seat and storage chamber, and a second part with a flexible valve cover and actuator. The storage chamber may be formed from a pre-form blow-molded into a flexible pouch defining a variable-volume storage chamber. The flexible valve cover and valve seat form a normally closed valve seam therebetween. The valve cover is movable in response to fluid at an inlet to the seam exceeding a valve opening pressure of the one-way valve between (i) a normally closed position with valve cover and valve seat in contact with each other and defining the normally closed seam, and (ii) a second position with at least a portion of the valve cover spaced away from the valve seat to allow the fluid to pass through the seam. The one-way valve may have anti-spritz features for using the device to dispense a substance, such as to the eye.
    Type: Application
    Filed: January 18, 2013
    Publication date: July 25, 2013
    Inventor: Daniel Py
  • Patent number: 8491528
    Abstract: Devices, systems, and methods interface a cassette with an eye treatment system console to provide coupling between the console and an eye treatment probe. The console may receive the cassette using a driven axial translation linkage that inhibits rotation of the cassette. The cassette may facilitate accurately positioning of a pressure sensor relative to a the console by allowing sliding movement between the sensor and a cassette body. Multiple peristaltic drives may be mounted to the console so that their rotors rotate about a common axis. An integrated mount structure may support and/or position components of the console which will interface with cassette, and an axially compressible vacuum connector of the console seal to a tapered vacuum coupler of the cassette.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: July 23, 2013
    Assignee: Abbott Medical Optics Inc.
    Inventors: John I. Muri, Craig Edwards
  • Publication number: 20130184661
    Abstract: A punctal plug or lacrimal insert comprising a microelectromechanical system pump and associated reservoir may be utilized to deliver precise dosages of an active agent into the eye though the tear film. The microelectromechanical system pump comprises four main components; namely, a reservoir, a pump, a series of valves and a vent. The microelectromechanical system pump is positioned within a cavity in the punctal plug. The microelectromechanical system pump is positioned with a cavity in the punctal plug.
    Type: Application
    Filed: January 16, 2012
    Publication date: July 18, 2013
    Inventors: Stephen R. Beaton, Michael Ferran, Justin Scott Jacobs, Jason M. Tokarski, Christopher S. Gudeman, Fardad Chamran, Paul J. Rubel, Bret A. Coldren
  • Publication number: 20130172831
    Abstract: This invention provides for a device and methods of dispensing a precise predetermined volume of liquid of discrete drops, vapor, or mist while preventing contamination due to Pull Back and ensuring precision dispensing.
    Type: Application
    Filed: August 30, 2012
    Publication date: July 4, 2013
    Inventors: Leslie A. VOSS, Gary S. Hall, Catie A. MORELY
  • Patent number: 8469934
    Abstract: The present invention is directed to a pulsatile ophthalmic peri-corneal drug delivery device. The device includes an annular body and a mechanism for releasing multiple separate and distinct doses of a therapeutic composition over an extended period of time.
    Type: Grant
    Filed: January 25, 2011
    Date of Patent: June 25, 2013
    Assignee: Alcon Research, Ltd.
    Inventors: Alan L. Weiner, Bhagwati P. Kabra
  • Patent number: 8444610
    Abstract: This assembly is of the type including: a vessel (4) for containing liquid, the vessel (4) having a neck (14); a dispensing dropper end fitting (6) disposed at the end of the neck (14); and a cap (8) for closing the vessel (4), provided to be screwed onto the neck (14). In a preferred embodiment, the cap (8) and the neck (14) have safety element preventing the cap (8) from being unscrewed simply by applying an unscrewing torque, and allowing the cap (8) to be unscrewed when an additional action is applied together with the torque for unscrewing the cap (8).
    Type: Grant
    Filed: January 3, 2008
    Date of Patent: May 21, 2013
    Assignee: Rexam Pharma
    Inventor: Guillaume Grevin
  • Publication number: 20130096517
    Abstract: An eyewash dispensing container to store and deliver an eyewash fluid that is particularly suitable for terminal sterilization. The container includes a base and a locking lid with a tamper indicator. The container is able to be opened quickly and deliver the eyewash fluid directly to an eye of a user.
    Type: Application
    Filed: October 17, 2011
    Publication date: April 18, 2013
    Applicant: Niagara Pharmaceuticals Inc.
    Inventors: Steven C. Leistner, Ronya Ripenburg, Michael D. Murphy
  • Publication number: 20130085460
    Abstract: This invention provides for a method and a device for dispensing precise quantities of a predetermined volume of medicaments or other liquids onto the eye, via one or more discrete drop(s) generated by the device in a practical and innoxious way to users.
    Type: Application
    Filed: October 1, 2012
    Publication date: April 4, 2013
    Applicant: Johnson & Johson Vision Care, Inc.
    Inventors: Leslie A. Voss, Catie A. Morley, Gary S. Hall
  • Patent number: 8403899
    Abstract: Maggot debridement therapy dressing embodiments and methods are discussed for the treatment of a variety of indications including wound care, including septic wound care and the like.
    Type: Grant
    Filed: July 6, 2009
    Date of Patent: March 26, 2013
    Assignee: Monarch Labs LLC
    Inventor: Ronald A. Sherman
  • Patent number: 8342370
    Abstract: A one dose at a time, non-pressurized fluid dispensing canister from which the or each dose is dispensed as a result of two surfaces (21, 22) of the canister moving towards one another under the control of the user, wherein the canister incorporates a mechanism which, once a first dose has been dispensed, automatically prevents any further dispensing movement of the surfaces (21, 22) (in the case where the canister is a one-dosage only canister) or (where the canister is a multiple-dosage-dispensing canister) allows such movement only after the two surfaces (21, 22) have first been moved in a direction or directions other than that which alone caused the first dose to be dispensed.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: January 1, 2013
    Assignee: Norwich Pharma Technologies Limited
    Inventors: Calvin John Ross, Steven John Sansom
  • Publication number: 20120330251
    Abstract: A gravity-fed, emergency eyewash station includes a flow regulator in the feed line between the solution bag and the dispensing nozzle to maintain a constant flow rate throughout the entire activation time frame. The flow regulator uses a float valve to variably open and close an orifice that feeds the dispensing nozzle. Solution enters the flow regulator from an orifice at the top and leaves from an opening at the bottom. Solution flowing into and out of the regulator quickly reaches an equilibrium state, resulting in a constant flow rate for the entire activation time frame.
    Type: Application
    Filed: November 29, 2011
    Publication date: December 27, 2012
    Applicant: HONEYWELL INTERNATIONAL, INC.
    Inventors: Raymond Allen Boissonneault, Kelli Piotti
  • Patent number: 8328775
    Abstract: The present invention relates to a metered drop bottle for dispensing microliter amounts of a liquid in the form of a drop comprising: (a) a bottle with a flexible portion on the walls to decrease the internal volume by a fixed volume; (b) a plunger with a fixed stroke for depressing the flexible portion of the walls of the bottle; and (c) a nozzle tip having an internal and/or outer diameter no more than 1.2 mm.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: December 11, 2012
    Assignee: Sun Pharma Advanced Research Company Limited
    Inventors: Satish Madhukar Gokhale, Abhijit Takale, Prashant Kane
  • Publication number: 20120310185
    Abstract: The invention relates to a bottle for packaging a liquid with dropper delivery comprising a reservoir with an elastically deformable wall that can be reversed by letting air into the receptacle, surmounted by a dispensing head for the liquid comprising a drop-counting end-piece protruding to the outside of the bottle and an anti-bacterial filtering membrane, made partially hydrophilic and partially hydrophobic, which is interposed across the path of the liquid and of the air, at the base of the said end-piece. The dispensing head comprises an insert with a recessed body which contains a porous pad regulating the flow of liquid placed downstream of the reservoir and upstream of a chamber delimited downstream of the said membrane. At the base of this insert on the inner side of the bottle, longitudinal arches supporting a central pellet make star-shaped passageways radially guiding the air that enters the bottle after having passed through the porous pad.
    Type: Application
    Filed: February 3, 2011
    Publication date: December 6, 2012
    Applicant: Laboratoires Thea
    Inventors: Alain Defemme, Fabrice Mercier
  • Publication number: 20120296291
    Abstract: A device for dispensing liquid including a liquid reservoir which can be deformed so as to dispense liquid by pressing on the reservoir,a liquid-dispensing end piece fitted on the reservoir, a channel for the passage of liquid, a channel for the passage of air from the outside to the inside of the reservoir, the channel for the passage of air being closed off by a member made of an air-permeable polymeric material, this material being non-porous, the member being called the air-permeable member.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 22, 2012
    Inventors: Gaetan Painchaud, Guillaume Grevin, Xavier Julia, Thierry Decock, Thierry Rimlinger
  • Patent number: 8313472
    Abstract: An emergency eyewash station and dispensing structure therefore is disclosed. The emergency eyewash station includes a main body configured and arranged to hold and dispense eyewash fluid therefrom, an actuator arm assembly movable from a closed position to an open position, and a dispensing structure having an eyepiece sealed by a membrane. The eyepiece is in fluid connection with the eyewash fluid contained in the main body. The dispensing structure is removably coupled to the actuator arm assembly such that when the actuator arm assembly is moved from the closed position to the open position, the membrane is unsealed and the eyewash fluid dispenses from the eyepiece.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: November 20, 2012
    Assignee: Sperian Eye & Face Protection, Inc. a Delaware corporation
    Inventors: Benoit Devinat, Michael C Pereira, Breck Petrillo
  • Patent number: 8313449
    Abstract: Apparatuses, systems, and methods for applying reduced pressure to a tissue site on a foot are provided. An apparatus may include an insole and a tissue contacting surface covering at least a portion of the insole. At least one portion of the tissue contacting surface is removable to form a void. The apparatus may also include a reduced-pressure interface for receiving reduced pressure from a reduced-pressure source, and at least one flow channel fluidly coupled to the reduced-pressure interface and the void.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: November 20, 2012
    Assignee: KCI Licensing, Inc.
    Inventors: Ian James Hardman, Colin John Hall, Keith Patrick Heaton
  • Patent number: 8287505
    Abstract: A dispensing tip apparatus for an eye drop dispenser to administer topical ophthalmic solutions is described. The apparatus integrates an ophthalmic solution-dispensing tip with an optical gauging assembly. The tip provides continuous visual feedback about it orientation and relationship to the eye. The dispensing tip when attached to any standard topical ophthalmic solution dispensing bottle or reservoir enables the user to view a target, visually align the dispenser tip, and administer an eye drop with precision. There is also a visual feedback by which the dispenser tip is prevented from gaining too close proximity and contacting the eye, thus preventing contamination of the medication and its dispenser. The visual feedback can also contain textual or graphic information that serves as a promotional advertisement. The is assembly can be attached to the neck of an eye drop bottle or attached to the tip of an eye drop bottle.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: October 16, 2012
    Inventor: Jerrold Scott Pine
  • Patent number: 8246589
    Abstract: Precision lid retracting eyedropper device with a hollow, rigid housing having an upper aperture that allows a push button topped piston to enter the housing where the piston can impinge on a resilient tubular member that is part of a pump assembly. The housing also includes a solution storing chamber that feeds solution to the pump assembly. A solution exit tube attached to the outgoing portion of the pump assembly emanates from the bottom part of the housing and can be directed towards the user's eye. Integral downwardly facing resilient legs are placed just above and below the user's orbital ridge so that when the legs are squeezed and released, the user's eye lids are forced open allowing the user to dispense a precise amount of solution into his or her eye.
    Type: Grant
    Filed: January 12, 2009
    Date of Patent: August 21, 2012
    Inventor: Alvin J. Marx