By Catheter Patents (Class 604/508)
  • Patent number: 9956377
    Abstract: A renal flow system injects a volume of fluid agent into a location within an abdominal aorta in a manner that flows bilaterally into each of two renal arteries via their respectively spaced ostia along the abdominal aorta wall. A local injection assembly includes two injection members, each having an injection port that couples to a source of fluid agent externally of the patient. The injection ports may be positioned with an outer region of blood flow along the abdominal aorta wall perfusing the two renal arteries. A flow isolation assembly may isolate flow of the injected agent within the outer region and into the renals. The injection members are delivered to the location in a first radially collapsed condition, and bifurcate across the aorta to inject into the spaced renal ostia. A delivery catheter for upstream interventions is used as a chassis to deliver a bilateral local renal injection assembly to the location within the abdominal aorta.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: May 1, 2018
    Inventors: Jeffrey M. Elkins, Aurelio Valencia, Samir R. Patel, Ricardo Aboytes, Harry B. Goodson, Craig A. Ball
  • Patent number: 9907946
    Abstract: Apparatus and methods of dispensing fluid intravenously to a subject, and of flushing a line of an intravenous fluid administration apparatus, are provided. The apparatus may include a chamber including a plurality of connector ports and be configured to operate in fluid communication with an upstream source via a first connector port and, during operation, pass therethrough to downstream tubing, under a first pressure condition, first fluid from the upstream source via a second connector port. A third connector port may be configured to connect to an end of tubing or a valve connector such that, during operation, the chamber is configured to, under a second, higher pressure condition, pass therethrough to the downstream tubing a second fluid from a second fluid source via the third and second connector ports, prevent first fluid flow into the downstream tubing, and prevent second fluid flow through the first connector port.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: March 6, 2018
    Inventor: Joel S. Faden
  • Patent number: 9901728
    Abstract: The present invention relates to a catheter connector assembly having an insert for use during packaging, shipping, and handling of a catheter connector. The assembly includes a catheter connector having a body with a first half axially aligned with a second half. The first half is rotatable relative to the second half between an open position and a closed position. The first half defines a distal end of the body and the second half defines a proximal end of the body. A proximal end port is configured with the proximal end of the second half for mating communication with a fluid delivery device. The insert is configured with the body when the body is in the open position such that the insert maintains the catheter connector in the open position during packaging, shipping, and handling of the catheter connector.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: February 27, 2018
    Assignee: Avent, Inc.
    Inventor: Steve Saeed Khalaj
  • Patent number: 9801987
    Abstract: A bifurcated cannula for directing blood into the arterial system. The bifurcated cannula including an ingress channel and first and second egress channels. The first egress channel directs a first portion of the blood entering the bifurcated cannula into the arterial system in a first direction. The second egress channel directs a second portion of the blood entering the bifurcated cannula into the arterial system in a direction that opposes the first direction.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: October 31, 2017
    Assignee: CircuLite, Inc.
    Inventors: Robert C. Farnan, John P. Budris
  • Patent number: 9629981
    Abstract: A multipurpose catheter includes an un-tapered portion and a tapered portion, the latter being disposed distally of the former. The catheter has an arrangement of echo reflective features over at least a portion of the tapered portion. The echo reflective features may be echo reflective solely due to their shape, or may be made of radio opaque materials, and thus may provide a degree of echogenicity not only due to their material but also due to the reflectivity of their shape.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: April 25, 2017
    Assignee: DOLCERA INFORMATION TECHNOLOGY SERVICES PRIVATE LIMITED
    Inventors: Praveen Thungana, Abhinandan Bhattacharya, Lakshmikant Goenka, Sumair Riyaz Hakaim, Anil Sharma
  • Patent number: 9605260
    Abstract: Provided herein are compositions and methods for the alteration of neuronal methylation by synthetic piRNAs or by alteration of piRNA function. Such alterations find use in the regulation and control of neural gene expression and concomitant neural functions. Further provided herein are systems and methods for the identification of target sites for regulation by piRNAs.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 28, 2017
    Assignee: IBIS BIOSCIENCES, INC.
    Inventors: David J. Ecker, Todd P. Michael, Lendell L. Cummins, Mark W. Eshoo, Stanley T. Motley, Danny M. Chou
  • Patent number: 9586031
    Abstract: Angioplasty and other dilatation devices are provided with scoring elements which incorporate a drug to be delivered to a body lumen, typically a blood vessel. The scoring elements have drugs and other active substances coated over a portion thereof or incorporated within internal structure of the element so that the drug is released into the luminal wall closely associated diseased regions of the body lumen as the scoring structure is radially expanded into the wall.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 7, 2017
    Assignee: AngioScore, Inc.
    Inventors: Eitan Konstantino, Michal Konstantino
  • Patent number: 9480524
    Abstract: An apparatus and method for treatment of a tubular anatomical structure is disclosed. The method includes using an electrical energy to destroy elongated cells on the tubular anatomical structure. The apparatus may include one or more electrodes for creating an electric field, and a cooling system for carrying heat away from the electrode. The elongated cells can include nerve cells on the tubular anatomical structure.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: November 1, 2016
    Assignee: Angiodynamics, Inc.
    Inventors: Victor Chorenky, Ali Jaafar
  • Patent number: 9433427
    Abstract: In one embodiment an aspiration system includes an elongate tubular member having a lumen; an aspiration catheter configured to be inserted through the lumen of the elongate tubular member, and including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of the elongate tubular member at the distal end of the elongate tubular member; an elongate support member coupled to the tubular aspiration member and extending between a proximal end of the aspiration catheter and the proximal end of the tubular aspiration member; and an annular sealing member coupled to the tubular aspiration member and configured to create a seal against an inner surface of the elongate tubular member, when a vacuum sufficient to cause aspiration is actively applied to the lumen of the elongate tubular member.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: September 6, 2016
    Assignee: INCUVATE, LLC
    Inventors: David M. Look, Bradley S. Culbert
  • Patent number: 9248221
    Abstract: In one embodiment, system for real time monitoring of catheter aspiration includes a housing having a first port adapted for connection to a vacuum source and a second port adapted for connection with an aspiration catheter, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold. In another embodiment, the system for real time monitoring of catheter aspiration further includes a vacuum source for connection to the first port and an aspiration catheter having an aspiration lumen for connection to the second port.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: February 2, 2016
    Assignee: INCUVATE, LLC
    Inventors: David M. Look, Bradley S. Culbert
  • Patent number: 9242068
    Abstract: An infusion catheter includes a catheter body having a proximal end, a distal end, and two or more lumens extending therethrough. The infusion catheter also includes an infusion tube having a proximal end, a distal end, and one or more ports disposed therethrough. The first lumen of the catheter body is in fluid communication with the lumen of the infusion tube. A central member has a distal end connected to the distal end of the infusion tube, a proximal end, and a proximal portion slidably received in the second lumen of the catheter body. The infusion tube is disposed relative to the central member such that axial advancement of the central member relative to the catheter body radially collapses the infusion tube over the central member and axial retraction of the central member relative to the catheter body radially expands the infusion tube about the central member.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: January 26, 2016
    Assignee: Covidien LP
    Inventors: Michael Thai, Thomas Chien, Kelvin Ning, Robert Mcrae
  • Patent number: 9233200
    Abstract: A split-tip catheter for placement within the vasculature of a patient and for use in hemodialysis or other suitable procedures. In one embodiment, the split-tip catheter includes a catheter body defining a first lumen and a second lumen, and a split distal region extending from a distal end of the catheter body. The split distal region includes an arterial segment defined by an outer wall enclosing an arterial segment lumen, the arterial segment lumen in fluid communication with the catheter body first lumen, and a venous segment defined by an outer wall enclosing a venous segment lumen, the venous segment lumen in fluid communication with the catheter body second lumen, the venous segment outer wall extending from the catheter body distal end to a distal nose portion. The distal nose portion may taper distally from a first outer perimeter to a second outer perimeter smaller than the first outer perimeter.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: January 12, 2016
    Assignee: C.R. Bard, Inc.
    Inventors: Colin S. Gregersen, Ryan T. Moehle, Ryan C. Patterson
  • Patent number: 9227024
    Abstract: One or more intravenous catheter assemblies are monitored to ensure compliance with required hygienic procedures and/or to ensure only persons who have properly sanitized their hands are allowed to attend to such catheter assemblies. Detecting electrodes incorporated as part of such catheter assemblies facilitate determination as to whether potential contamination may have occurred. The hygienic status of a health care worker attending to the catheter assembly, as possibly evidenced by detected use of a sanitizer, may be used to determine whether the catheter assembly is being subjected to contamination.
    Type: Grant
    Filed: June 12, 2012
    Date of Patent: January 5, 2016
    Inventor: Richard Deutsch
  • Patent number: 9168163
    Abstract: A needle system for providing fluidic and/or instrument access to an internal body structure. Exemplary embodiments may include non-linear needles having anatomically appropriate lengths and curvatures. Some exemplary embodiments may include a pivotable base, which may assist in stabilizing the needle system with respect to a body structure and/or may be reconfigurable into a safety guard position. Exemplary needle systems may include expandable conduits providing fluidic and/or instrument pathways into internal body structures.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: October 27, 2015
    Assignee: P Tech, LLC
    Inventor: Peter M. Bonutti
  • Patent number: 9161830
    Abstract: Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.
    Type: Grant
    Filed: January 3, 2014
    Date of Patent: October 20, 2015
    Assignee: ATRITECH, INC.
    Inventors: Thomas E. Borillo, Dean A. Peterson, Gregg Sutton, Jeffrey Welch
  • Patent number: 9132000
    Abstract: Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: September 15, 2015
    Assignee: ATRITECH INC.
    Inventors: Robert A. VanTassel, Robert G. Hauser, Robert Schwartz, David Holmes, Gregg S. Sutton, Thomas E. Borillo, Jeffrey Welch
  • Patent number: 9101737
    Abstract: Tear-away sheath introducers for catheters, methods for making such introducers, and methods for using such introducers are described. A splittable sheath introducer may include a sheath, a hub disposed at a proximal end of the sheath, a valve included with the hub, and a valve actuator movable from a first position to a second position, the valve actuator opening the valve when in the second position. The valve actuator may include a retaining member that enables the valve actuator to be retained by a portion of the hub when the sheath introducer is split apart.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: August 11, 2015
    Assignee: C. R. Bard, Inc.
    Inventor: Eric M. King
  • Patent number: 9050205
    Abstract: Described herein are flexible implantable occluding devices that can, for example, navigate the tortuous vessels of the neurovasculature. The occluding devices can also conform to the shape of the tortuous vessels of the vasculature. In some embodiments, the occluding devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Some embodiments describe methods and apparatus for adjusting, along a length of the device, the porosity of the occluding device. In some embodiments, the occluding devices allows adequate blood flow to be provided to adjacent structures such that those structures, whether they are branch vessels or oxygen-demanding tissues, are not deprived of the necessary blood flow.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: June 9, 2015
    Assignee: Covidien LP
    Inventors: Aaron Lee Berez, Quang Quoc Tran
  • Publication number: 20150148779
    Abstract: Apparatus for delivering material into a patient includes a catheter having a proximal end and a distal end. Material, preferably of filamentary or thread form, is fed from a material supply into a Y-fitting having a main branch and a side branch. The side branch is connected to a source of driving fluid able to feed drive fluid under pressure into the material carrier so as to pull material forwardly and out of the distal end of the catheter. The assembly includes an inner cannula within which material is passed from the material source. This increases the speed of delivery of material though the device and reduces the amount of drive fluid which is required.
    Type: Application
    Filed: November 20, 2014
    Publication date: May 28, 2015
    Inventors: Aidan FUREY, Anders Ginge JENSEN
  • Publication number: 20150148778
    Abstract: Devices, systems, and methods for performing injections with lowered likelihood of infection include catheters and other injection means with protective coverings. The protective covering can protect the catheter or other injection means before, during, or before and during insertion of the catheter into an insertion site. The protective covering includes two or more parts of interlocking protrusions and channels that allow for sliding motion of the parts relative each other but that resist separation of the parts in the direction perpendicular to the long axis of the two or more parts.
    Type: Application
    Filed: August 22, 2013
    Publication date: May 28, 2015
    Inventors: Alexander Mellon Eaton, Gabriel Mikal Gordon, Dyson William Hickingbotham
  • Patent number: 9039657
    Abstract: Implantable devices and methods for delivering drugs and other substances to locations within the body of a human or animal subject to treat or diagnose sinusitis and a variety of other disorders. The invention includes implantable substance delivery devices that comprise reservoirs and barriers that control the rate at which substances pass out of the reservoirs. The delivery devices may be advanced into the body using guidewires, catheters, ports, introducers and other access apparatus. In some embodiments the delivery devices may be loaded with one or more desired substance before their introduction into the body. In other embodiments the delivery devices are loaded and/or reloaded with a desired substance after the delivery device has been introduced into the body.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: May 26, 2015
    Assignee: Acclarent, Inc.
    Inventors: Joshua Makower, John Y. Chang, Julia D. Vrany, Amrish Jayprakash Walke
  • Patent number: 9039665
    Abstract: A membrane-free perfusion catheter comprising an exchange surface having a filament structure, a delivery unit for delivery of perfusion fluid to a lumen of the filament structure in a manner to allow for an exchange of substances between a medium surrounding the lumen and the perfusion fluid via the filament structure, and a drain unit for draining the medium surrounding the exchange surface and/or for draining the perfusion fluid delivered to the lumen of the filament structure after the exchange of substances between the medium surrounding the lumen and the perfusion fluid via the filament structure.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: May 26, 2015
    Assignee: Joanneum Research Forschungsgesellschaft MBH
    Inventors: Manfred Bodenlenz, Christian Hoefferer, Thomas Birngruber, Lukas Schaupp
  • Publication number: 20150141958
    Abstract: A vascular access needle assembly is disclosed. The needle assembly contains a needle and a sheath. The needle has a first part, a second part, and a third part. The needle contains a pointed end configured to penetrate skin of a patient and a sheath slidably and rotatably coupled with the needle. The sheath having one or more irrigation slots configured to transmit a fluid from a fluid source to a vascular region.
    Type: Application
    Filed: October 16, 2014
    Publication date: May 21, 2015
    Inventor: Sukhjit Gill
  • Publication number: 20150141959
    Abstract: Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally and radially along the blood vessel. Confirmation that a delivery aperture of the needle lies beyond the EEL may be required before delivering the pharmaceutical agent. In one example, the catheters are used to deliver dexamethasone and other anti-inflammatory agents to the peripheral and other vasculature to treat peripheral vascular disease and other conditions.
    Type: Application
    Filed: January 26, 2015
    Publication date: May 21, 2015
    Inventor: Kirk Patrick Seward
  • Publication number: 20150141898
    Abstract: A medical system for endovascular temperature control of blood and for recanalization of a blood vessel, the medical system having a catheter, a radially compressible treatment device, in particular a recanalization device, which, in the compressed state, is arranged to be longitudinally movable in the catheter and, by being released from the catheter, is radially expandable for the recanalization of the blood vessel, and a temperature control element for controlling the temperature of blood, wherein the treatment device, in particular the recanalization device, can be positioned distally with respect to the temperature control element in such a way that, during use, blood which is temperature-controlled by the temperature control element flows to the recanalization site in the blood vessel.
    Type: Application
    Filed: May 14, 2013
    Publication date: May 21, 2015
    Applicant: ACANDIS GMBH & CO. KG
    Inventor: Giorgio Cattaneo
  • Patent number: 9033954
    Abstract: A catheter for insertion into a vascular system of a patient and for directing fluid flow includes a catheter body having a longitudinal axis and longitudinally spaced proximal and distal catheter ends with an intermediate catheter portion defined therebetween. An intermediate catheter outlet in the catheter body is located in the intermediate catheter portion and is spaced longitudinally from the proximal and distal catheter ends. A first lumen is defined within the catheter body and has longitudinally spaced proximal and distal first lumen ends with a reversing bend located therebetween, the first lumen providing fluid communication between the proximal catheter end and the intermediate catheter outlet. The reversing bend is located longitudinally between the intermediate catheter outlet and the distal catheter end. The reversing bend directs fluid flow to turn approximately 180° as the fluid flows through the first lumen. A method of using the catheter is also described.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: May 19, 2015
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventor: Rafi Avitsian
  • Publication number: 20150119854
    Abstract: Tear-away sheath introducers for catheters and methods for making and using such introducers are described. The sheath introducers contain movable valves that are encapsulated in a movable housing that allows the valve to move along the introducer axis. As the movable valve and housing travel along the axis, a portion of the hub protrudes past the valve and is exposed. As well, the sheath introducers can also contain a stationary valve and housing that can be opened to expose a portion of the hub when a conduit penetrates the stationary valve. The conduit can include a one-way, two-way, or other suitable valve actuator that can penetrate and open the valve, yet remain attached to a portion of the introducer when the introducer is split for removal from a patient. In both instances, the protruding portion of the hub contains a friction-free pathway for a catheter into the sheath introducer.
    Type: Application
    Filed: December 30, 2014
    Publication date: April 30, 2015
    Inventors: Eric M. King, Spencer R. Thomas
  • Publication number: 20150119853
    Abstract: A method of controlling and changing the shape of a catheter in situ that includes the use of two nested catheters. The catheters have two different shapes that may add, cancel, or override each other when one catheter is placed within the other. The shape may be changed by advancing or rotating one catheter relative to the other catheter.
    Type: Application
    Filed: October 29, 2014
    Publication date: April 30, 2015
    Inventors: John P. Gainor, Robert F. Wilson, Uma S. Valeti
  • Publication number: 20150119852
    Abstract: An improved catheter insertion assembly having a transparent tubular member open at each end; a plunger assembly slidable within the tubular member having a stem portion at a first end; and at least a partially transparent chamber having a needle base and sealing member on a second end of the plunger assembly; an elongated tubular needle embedded within the needle base and extending there from with the needle in fluid communication with the transparent chamber; a catheter assembly, a transparent cannula and a transparent hub attached to the second end with the tubular needle passing longitudinally through the cannula; a fluid passage formed between the needle and the cannula so that when the plunger is retracted a vacuum is established within the fluid passage and blood is visibly drawn through the fluid passage into the transparent cannula and if volume permits, blood then would be visible in the transparent hub, and then if volume permits blood would be visible in the void of the catheter body (barrel) crea
    Type: Application
    Filed: January 13, 2014
    Publication date: April 30, 2015
    Inventor: Toby Wexler
  • Publication number: 20150112304
    Abstract: An apparatus having a distal end that may be selectively bent in situ. The apparatus has a curved configuration and a substantially straightened configuration. First and second tubular components of the apparatus each include a distal portion that is at an acute angle with respect to a longitudinal axis of the apparatus. The second tubular component is rotatably disposed within the first tubular component. In the curved configuration, the distal portions of the first and second tubular components are positioned to extend at substantially the same acute angle with respect to the longitudinal axis of the apparatus. In the substantially straightened configuration, the distal portions of the first and second tubular components are positioned such that the curvatures thereof counterbalance each other. The first and second tubular components may be used in an occlusion bypassing apparatus for re-entering the true lumen of a vessel after subintimally bypassing an occlusion.
    Type: Application
    Filed: October 21, 2013
    Publication date: April 23, 2015
    Applicant: INVATEC S.p.A
    Inventor: Claudio Silvestro
  • Publication number: 20150112307
    Abstract: In one instance, a catheter for replacing or adding a guide wire into a patient is provided. The catheter includes a first rapid exchange lumen, a second rapid exchange lumen, and a releasable wire-securing device. A second guide wire is placed in the second rapid exchange lumen and secured into position. The catheter is then advanced along the first guide wire until in position, and then the second guide wire is released from the wire-securing device and advanced into the desired position. The catheter is then removed. Other catheters and methods are also disclosed.
    Type: Application
    Filed: December 20, 2013
    Publication date: April 23, 2015
    Applicant: Wayne Margolis Family Partnership, Ltd.
    Inventor: Wayne Margolis
  • Publication number: 20150112305
    Abstract: A fluid transport apparatus includes: a first electrode provided on the insulating transporting tube which constitutes part of a flow channel in which conductive fluid is transported, and configured not to come into contact with the fluid in the flow channel a second electrode configured to come into contact with fluid in the flow channel; and a determining unit connected to the first electrode and the second electrode, and configured to determine a trouble of the transporting tube. Accordingly, the trouble of the transporting tube is determined.
    Type: Application
    Filed: October 17, 2014
    Publication date: April 23, 2015
    Inventor: Makoto KATASE
  • Publication number: 20150112195
    Abstract: Cryocatheter including an elongated flexible catheter member having a short rigid catheter tip for introduction into a therapy site and a heat exchange arrangement for freezing the catheter tip to a cryo-temperature from between about ?15° C. to about ?30° C. for freezing human tissue at the therapy site. Cerebral medical procedures include inter alia employing a local ice ball for sealing a bleeding rupture in an arterial wall in the case of a stroke hemorrhage, employing a local ice ball for mapping electrical disorder foci in a brain, for example, epileptic foci, and the like.
    Type: Application
    Filed: October 10, 2014
    Publication date: April 23, 2015
    Inventors: Abraham BERGER, Avri HAZAN
  • Publication number: 20150100040
    Abstract: A medical material supply device which can percutaneously supply a material for nerve regeneration that promotes the regeneration of a nerve is insertable into a vessel and includes: a supply section configured to penetrate from an inner wall to an outer wall of the vessel at a predetermined position in the vessel, thereby being able to supply a material for nerve regeneration to the outer wall of the vessel; and an elongated body which is inserted into the vessel, in which the supply section is provided with a linear portion which is provided at the elongated body and is configured to penetrate from the inner wall to the outer wall of the vessel.
    Type: Application
    Filed: October 8, 2014
    Publication date: April 9, 2015
    Inventors: Risato KOBAYASHI, Ichirou HIRAHARA
  • Patent number: 8992591
    Abstract: An improved delivery system for an implantable medical device includes a retention sheath having a proximal end, a distal end, and an inner lumen extending from the proximal end to the distal end. The implantable medical device is disposed within the inner lumen of the retention sheath, which restrains the implantable medical device. A plurality of substantially incompressible rings are disposed within the inner lumen of the retention sheath in a stacked co-axial configuration that extends from the proximal end of the retention sheath in a pre-deployment position to a proximal end of the implantable medical device. Each ring in the plurality of separate rings abuts at least a portion of an adjacent ring. The plurality of separate rings is configured to prevent the implantable medical device from moving toward a proximal end of the retention sheath when the retention sheath is moved from the pre-deployment position to a deployment position.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: March 31, 2015
    Assignee: Cook Medical Technologies LLC
    Inventor: Fred T. Parker
  • Patent number: 8986281
    Abstract: A medical catheter assembly is provided including an inner catheter member, where that inner catheter member includes a plurality of inner catheter lumens, and an outer sheath with at least one patent sheath lumen. The inner catheter is slidably disposed through a length of the at least one patent sheath lumen in a manner providing a substantially sealing contact between an exterior surface of the inner catheter and an inward surface of the at least one patent sheath lumen. A first of the plurality of inner catheter lumens includes a plurality of apertures to the exterior surface of the inner catheter, and a second of the plurality of inner catheter lumens includes at least one distal end-tip opening. A method of using the assembly is also provided.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: March 24, 2015
    Assignee: Cook Medical Technologies LLC
    Inventor: Cleve S Koehler
  • Publication number: 20150080853
    Abstract: An aspiration thrombectomy catheter system includes an aspirator and an aspiration catheter for insertion in a blood vessel. The catheter has a shaft with a proximal end for connection with the aspirator and a tapering distal end with a tip for insertion in the vessel. A plurality of aspiration ports are arranged in sets along the tapering distal end, for aspirating thrombus from the vessel. At least one aspiration lumens within the shaft conducts thrombus from the vessel, through the aspiration ports, to the aspirator. Variably sized or shaped ports provide differing aspiration vectors for enhanced thrombus removal. The aspiration thrombectomy catheter additionally provides for uniform drug dispersion at a thrombotic area, alone or in combination with aspiration of the thrombus. In the event of an adverse reaction, drug dosage may be easily reduced by aspirating dispersed drugs back into the catheter.
    Type: Application
    Filed: November 25, 2014
    Publication date: March 19, 2015
    Inventor: Ron Smalling
  • Publication number: 20150073329
    Abstract: Devices, systems, and methods for autoretroperfusion.
    Type: Application
    Filed: November 18, 2014
    Publication date: March 12, 2015
    Inventor: Ghassan S. Kassab
  • Publication number: 20150051583
    Abstract: A catheter for use in medical applications is disclosed. The catheter comprises tubing with a tip hole at one end and an end portion at the other end. Fluid exits the catheter at the tip hole thereof. One or more alternative fluid pathway(s) are provided on the sidewall of the catheter to permit outflow of fluid medication from the catheter to ensure proper delivery of the medication to the intended target area, particularly when the tip opening is occluded or restricted for any reason.
    Type: Application
    Filed: January 4, 2013
    Publication date: February 19, 2015
    Inventors: Joshua Horvath, Victor Politis, Stephen Richards, Ronald Pettis, Gary Searle, Monica Rixman Swinney, Natasha Bolick
  • Publication number: 20150051536
    Abstract: Apparatus is provided for a reversible connection catheter comprising in combination a hub and a valve housing portion. The hub is composed of a tapered molded body having a narrow tapered end and an enlarged other end. The narrow tapered end has integrated therein a double lumen catheter projecting therefrom. Two bores extend through the hub each communicating with a distinctive lumen in the catheter. The valve housing portion is composed of a distal segment with two spaced through first openings, a proximal segment with two spaced through second openings and a resilient gasket portion with two spaced first female luers mounted between the proximal and distal segments. The valve housing further has a third opening in said proximal segment positioned between the first and second openings and a second female luer on the resilient gasket portion in alignment with said third opening to serve as a flushing valve. A structural member operatively holds the hub and valve housing portion together.
    Type: Application
    Filed: March 8, 2013
    Publication date: February 19, 2015
    Inventor: YAIR MENDELS
  • Patent number: 8951241
    Abstract: A medical device is disclosed, which comprises a functional unit (C) for permanent or temporary placement in the urogenital tract of a human or animal body. The functional unit has at least one electrically conducting portion. A power source (G) supplies a current to the electrically conducting portion after placement of the functional unit in the urogenital tract. In this manner, the growth of bacteria on the functional unit can be reduced.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: February 10, 2015
    Assignees: Universitat Zurich, ETH Zurich
    Inventors: Daniel Eberli, Lukas Hefermehl, Michael Gabi, Alexandre Lar-Magnac, Janos Voros
  • Publication number: 20150032085
    Abstract: According to some embodiments, a method of treating conditions affecting a liver of a subject is provided. The method may include delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
    Type: Application
    Filed: September 25, 2014
    Publication date: January 29, 2015
    Inventors: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
  • Publication number: 20150025616
    Abstract: One disclosed embodiment comprises a method for treating lesions in the carotid artery of a mammalian body. The method comprises transcervical access and blocking of blood flow through the common carotid artery (with or without blocking of blood flow through the external carotid artery), shunting blood from the internal carotid artery and treating the lesion in the carotid artery.
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Applicant: SILK ROAD MEDICAL, INC.
    Inventor: David W. Chang
  • Patent number: 8936795
    Abstract: A liquid embolic material may include a mixture of a first solution comprising between about 1.2% and about 2.5% weight per volume (w/v) carboxymethyl chitosan (CCN) in a first solvent and a second solution comprising between about 1.2% and about 2.5% w/v oxidized carboxymethyl cellulose (OCMC) in a second solvent. The liquid embolic material may be used to embolize a targeted embolization location by mixing the first solution and the second solution to form a liquid embolic material (or hydrogel precursor material), introducing the hydrogel precursor material to a targeted embolization location within a body of a patient, and allowing the CCN and the OCMC to react to form the hydrogel material and embolize the targeted embolization location.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: January 20, 2015
    Assignee: Regents of the University of Minnesota
    Inventors: Jafar Golzarian, Lihui Weng
  • Publication number: 20150018597
    Abstract: The present invention provides a kit for the delivery a therapeutic agent to an organ blood flow and the removal of the excess of said therapeutic agent from said organ blood flow, said kit comprises: (a) the therapeutic agent, (b) a first retrievable medical device (26), for delivering said therapeutic agent into the organ inflow, (c) a second retrievable medical device for isolating the organ outflow vessel and (d) a separation device (25) comprising at least one filter able to separate the therapeutic agent excess from the organ outflow, having an inlet (38) for the organ outflow having a therapeutic agent excess and an outlet (39) for filtered organ outflow.
    Type: Application
    Filed: March 1, 2013
    Publication date: January 15, 2015
    Inventors: Joop Fierens, Kevin Jason Nackard, Eric Thierry Jean Marcoux, Emmanuel J. Bartholome
  • Patent number: 8932270
    Abstract: A variable infusion length catheter includes a tube assembly having a plurality of coaxial tubes each with a plurality of side ports formed therein, and having among the tubes a plurality of different rotational configurations each defining a different pattern of fluid communication among the side ports and a corresponding different infusion length of the catheter. Related methodology is also disclosed.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: January 13, 2015
    Assignee: Cook Medical Technologies LLC
    Inventor: Therese J. O'Day
  • Publication number: 20140378411
    Abstract: The present invention relates to an injectable aqueous viscous solution for treating varicose veins. It also relates to a catheter system with cannulas for vascular puncture with double or triple cut tip comprising, (i) an outer cannula (non-cutting element), a tube-like construction which is slightly flexible, (a) the tip zone being tapered to ease introduction, (b) the edges being optionally rounded to provide atraumatic advancement (c) optionally with a Luer-lock connector (ii) a hollow needle which is flexible and bendable (c) optionally with a transparent flashback chamber, wherein (d) the diameter of the needle is below the diameter of the catheter, wherein (iii) the needle and outer cannula are connected by a temporary lock to ensure the needle tip is fixed in adequate position outside the outer cannula outer cannula during skin puncture and introduction towards the target region.
    Type: Application
    Filed: December 20, 2012
    Publication date: December 25, 2014
    Inventor: Johann Christof Ragg
  • Publication number: 20140371715
    Abstract: A safety needle system operable with a medical device includes: a housing with a needle mount having a needle; and a sheath telescopically engaged with the housing and surrounding the needle such that the sheath operates in a retracted position, in which the sheath exposes the needle, and an extended position, in which the sheath surrounds the needle. The sheath is coupleable to the medical device such that removal of the needle from the medical device draws the sheath over the needle, transitioning the sheath from the retracted position to the extended position. In one embodiment, the system includes a slider engaged with the sheath and/or housing and including a restraint that engages and disengages the sheath to respectively reinforce and weaken the coupling of the sheath and medical device. In another embodiment, the sheath includes a longitudinal track that slidingly engages a setting of the housing between sheath positions.
    Type: Application
    Filed: June 25, 2014
    Publication date: December 18, 2014
    Inventors: Nathan Farrell, Adrienne Rose Harris, Steven B. White, Ronald Dean Duis, Henry J.H. Brown
  • Patent number: 8905962
    Abstract: An artificial blood has a trunk portion with both ends connected to blood vessels, and access branch portions and a shunt branch portion branched from the trunk portion. The access branch portions are disposed with a solid column-shaped access port that plugs these branch portions. The access port has a solid center portion and a tube-shaped peripheral portion disposed to surround the center portion. The peripheral portion is harder than the center portion and prevents the needle from deviating from the inside of the center portion. This enables a puncture to be easily made in a therapy in which a puncture is highly frequently made in a blood vessel.
    Type: Grant
    Filed: June 13, 2011
    Date of Patent: December 9, 2014
    Assignee: Nikkiso Co., Ltd.
    Inventors: Takuji Asano, Daisuke Yokoyama, Yoshihiko Kinoshita
  • Patent number: 8905997
    Abstract: Disclosed herein are therapeutic compositions for treating and preventing diseases such as neointimal hyperplasia (NIH), where the compositions comprise a therapeutic particle that has a localized association with a blood vessel and a therapeutic agent, such as an anti-NIH agent. Methods of use of the therapeutic compositions are also disclosed.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: December 9, 2014
    Assignee: BIND Therapeutics, Inc.
    Inventors: Amy Grayson, Stephen E. Zale, David Dewitt