Therapeutic Material Introduced Or Removed Through A Piercing Conduit (e.g., Trocar) Inserted Into Body Patents (Class 604/506)
  • Patent number: 11324894
    Abstract: An assembly for a drug delivery device comprises a housing, a dose member which is displaceable in a proximal direction with respect to the housing for setting of a dose of a drug, a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member configured to define a clutch stop position. The clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose.
    Type: Grant
    Filed: July 28, 2021
    Date of Patent: May 10, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Strehl, Udo Leuschner, Norbert Besenhardt
  • Patent number: 11291671
    Abstract: The present invention provides for pharmaceutical preparations, devices, systems and methods for the treatment of otic diseases and conditions. In various embodiments, the preparations, devices, systems and methods enable sustained drug release for the treatment or prevention of hearing loss, infections, and other pathological conditions of cochlea and inner ear.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: April 5, 2022
    Assignee: O-Ray Pharma, Inc.
    Inventors: William H. Slattery, Thomas Smith, Erik Pierstorff, Marc M. Baum
  • Patent number: 11273262
    Abstract: A medicament delivery device includes a case, a first plunger, a second plunger arranged telescopically with the first plunger, a first drive spring biasing the second plunger relative to the case, and a second drive spring biasing the first plunger relative to the second plunger.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: March 15, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Uwe Dasbach
  • Patent number: 11253652
    Abstract: A device (1) for dispensing a substance to a patient comprising a cylindrical first container (2) containing the substance and a second container (3) containing a liquid. The device further comprises an injection device (4) and transfer mechanism (5) for transferring the liquid from the second container (3) to the first container (2) and from the first container (2) to the injection device (4). The first container (2) has a connection element (7) and a plunger (9) that can be moved between the first (6) and second ends (8). By moving the plunger (9) towards the first end (6), liquid contained therein can be dispensed via the injection device (4). The injection device (4) comprises a piercing cannula (15) and an indwelling cannula (16). In an initial position, a distal end region of the piercing cannula (15) extends coaxially in the interior of the indwelling cannula (16).
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: February 22, 2022
    Assignee: SHL MEDICAL AG
    Inventors: Christoph Egloff, Ludwig Daniel Weibel
  • Patent number: 11234729
    Abstract: Embodiments of the present invention disclose micro-lipo needle device and methods of making and using the same.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: February 1, 2022
    Assignee: AURASTEM LLC
    Inventors: Bradford A. Conlan, Lucas Fornace
  • Patent number: 11207508
    Abstract: Inventive embodiments disclosed herein include a catheter for dilating a sinus cavity lumen. The catheter includes a guide tube, having a proximal end and a distal end, that terminates in a distal tip; a sleeve member annularly positioned over the guide tube, wherein the sleeve member is movable relative to the guide tube and is capable of being advanced over the guide tube; and a balloon coupled to the sleeve member, wherein the balloon can be extendable and inflated at or beyond the end of the guide tube.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: December 28, 2021
    Assignee: Entellus Medical, Inc.
    Inventors: Thomas V. Ressemann, John R. Drontle, Anthony J. Hanson, Peter T. Keith
  • Patent number: 11202753
    Abstract: The present invention provides a method for generating an immune response in a subject, comprising administering to the subject's skin an immunizing composition from a SARS-CoV-2 pathogen, wherein the composition is administered with a microneedle delivery device.
    Type: Grant
    Filed: August 17, 2020
    Date of Patent: December 21, 2021
    Inventors: Sobin Chang, Daniel J. Nevrivy, Saiprasad Sankaranarayanan
  • Patent number: 11197984
    Abstract: Provided are a microneedle array capable of improving the visibility of an appearance inspection, and a manufacturing method of the same. A microneedle array is a microneedle array including: a sheet portion having a first surface and a second surface which oppose each other; and a plurality of needle portions arranged on the first surface of the sheet portion, in which the second surface of the sheet portion is configured by a rough surface having peak portions and valley portions, and an average transmittance of the sheet portion in a wavelength range of 300 nm to 740 nm is 75% or less.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: December 14, 2021
    Assignee: FUJIFILM Corporation
    Inventor: Kenichiro Tamaki
  • Patent number: 11154281
    Abstract: A plug delivery system and method of use. The plug delivery device includes a support leg, a plunger, and an extractor. The support leg includes an internal receiving space configured to receive an implanted coaxial needle assembly through an opening in the distal end. The plunger extends at least partially through the internal receiving space of the support leg and has a longitudinally adjustable relation with respect to the support leg. The extractor is also configured to translate in a longitudinal direction with respect to the support leg and has a needle connection component configured to engage the coaxial needle assembly. The extractor can be moved distally in the longitudinal direction to engage the coaxial needle assembly and then moved distally to concurrently retract the coaxial needle assembly while the plunger remains relatively stationary to deploy the sealant plug residing in the coaxial needle assembly.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: October 26, 2021
    Assignee: Med-Genesis, LLC
    Inventors: Frederick Ahari, John S. Fisher, Jon Frederick Roever
  • Patent number: 11150168
    Abstract: A device for isolating a microbe or a virion includes a semiconductor substrate; and a trench formed in the semiconductor substrate and extending from a surface of the semiconductor substrate to a region within the semiconductor substrate; wherein the trench has dimensions such that the microbe or the virion is trapped within the trench.
    Type: Grant
    Filed: January 3, 2020
    Date of Patent: October 19, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Yann Astier, David Esteban, Judson R. Holt, Henry K. Utomo
  • Patent number: 11134985
    Abstract: Subcutaneous implantation tools and methods of implanting a subcutaneous device using the same. The tool may include a tool body having a longitudinally extending recess having a distal opening and having a tunneler at a distal end of the tool body extending from the distal opening of the recess. The tool may include a plunger slidably fitting within at least a portion of the tool body recess. The recess may be configured to receive an implantable device and the tunneler preferably extends distally from the recess at a position laterally displaced from the device when the device is so located in the recess. Movement of the plunger distally within the recess advances the device distally out of the recess and alongside of and exterior to the tunneler.
    Type: Grant
    Filed: May 18, 2021
    Date of Patent: October 5, 2021
    Assignee: Medtronic, Inc.
    Inventors: Matthew T. Vanderpool, Michael R. Klardie, Kris A. Peterson
  • Patent number: 11134986
    Abstract: Subcutaneous implantation tools and methods of implanting a subcutaneous device using the same. The tool may include a tool body having a longitudinally extending recess having a distal opening and having a tunneler at a distal end of the tool body extending from the distal opening of the recess. The tool may include a plunger slidably fitting within at least a portion of the tool body recess. The recess may be configured to receive an implantable device and the tunneler preferably extends distally from the recess at a position laterally displaced from the device when the device is so located in the recess. Movement of the plunger distally within the recess advances the device distally out of the recess and alongside of and exterior to the tunneler.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: October 5, 2021
    Assignee: Medtronic, Inc.
    Inventors: Matthew T. Vanderpool, Michael R. Klardie, Kris A. Peterson
  • Patent number: 11123140
    Abstract: An electronic computing system creates a treatment plan and provides safe and accurate treatment recommendations by obtaining an input image of a face; comparing, using a pattern recognition process, one or more aspects of the input image to corresponding aspects of a plurality of reference images; obtaining, based on a result of the comparing, supplemental information associated with one or more additional characteristics of the face; and creating a treatment plan based on the input image and the additional characteristic.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: September 21, 2021
    Inventors: Iliana E. Sweis, Bryan C. Cressey
  • Patent number: 11116907
    Abstract: An actuating device having integrated plunger is configured to be removably mounted to an automatic mixing device for a syringe. The actuating device includes lower and upper housings, a trigger member, a lockout ring, a mixing biasing member, a delivery plunger, a plunger biasing member, and a mixing plunger. The mixing plunger is releasably engaged with the trigger member in an initially locked state and engageable with at least one seal of the mixing device. The trigger member is operable to initiate decompression of the mixing biasing member and engagement of the mixing plunger with the at least one seal of the mixing device. The delivery plunger may also be activated to expand from a first, collapsed configuration to a second, expanded configuration by actuation of the trigger member.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: September 14, 2021
    Inventors: Oscar Frias Goyenechea, Richard A. Cronenberg
  • Patent number: 11077257
    Abstract: An autoinjector includes a case, a needle shroud telescopically coupled to the case, a carrier slidably arranged in the case, a collar rotatably and slidably disposed in the case and coupled to the needle shroud and the carrier, and a trigger button operably coupled to the carrier. The case includes a rib. The needle shroud is movable between a first extended position, a retracted position, and a locked second extended position. The carrier is adapted to hold a medicament container and movable from a first axial position to a second axial position relative to the case. The carrier abuts the rib in the first axial position and the needle shroud is in the first extended position and disengages the rib when the needle shroud is in the retracted position and the trigger button is pressed to advance the carrier to the second axial position.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: August 3, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Thomas Kemp
  • Patent number: 11071478
    Abstract: Systems, devices and methods are provided for inserting at least a portion of an in vivo analyte sensor, such as a dermal sensor, for sensing an analyte level in a bodily fluid of a subject. An applicator is positioned against a skin surface and a force is applied to the applicator causing at least a portion of a sharp and an in vivo analyte sensor to be positioned in the body of the subject. In particular, disclosed herein are embodiments of applicators designed to prevent premature sharp withdrawal and/or reduce the likelihood of improper sensor insertion. Also disclosed are embodiments of applicators including sharp modules having an angled sharp which can be configured to create an insertion path for a sensor.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: July 27, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Vivek S. Rao, Louis G. Pace, Hyun Cho, Benjamin Jay Feldman, Yi Wang, Tuan Nguyen
  • Patent number: 11065422
    Abstract: Devices, systems, and methods useful to engage tissue using suction and to perform medical procedures during sectional engagement. The present disclosure includes disclosure of a tension apparatus, comprising an elongated portion; and a head portion at a distal end of the elongated portion, the head portion comprising one or more arms, whereby a suction lumen extending along the elongated portion and the one or more arms terminates at one or more suction openings at each of the one or more arms.
    Type: Grant
    Filed: November 23, 2017
    Date of Patent: July 20, 2021
    Assignee: CVDevices, LLC
    Inventors: Ghassan S. Kassab, Matthew Phillips, H. Toby Markowitz
  • Patent number: 11058605
    Abstract: A device and method is disclosed for assembling a container holder in a clean environment, aseptically adding a solution to a primary container, inserting the primary container into the container holder, applying a first barrier to the container holder, sterilizing the container holder comprising the primary container and the applied first barrier to provide a sterilized container holder, assembling a fluid path module in a clean environment, the assembling comprising applying a second barrier to a first end of the sterilized fluid path module, sterilizing the fluid path module to provide a sterilized fluid path module and assembling a delivery device comprising the sterilized container holder and the sterilized fluid path module.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: July 13, 2021
    Assignee: FLEX LTD.
    Inventors: Eyal Barmaimon, Lior Shtram, Shai Finkman, Christian Riva, Tommaso Borghi, David Ward
  • Patent number: 11060960
    Abstract: A device for isolating a microbe or a virion includes a semiconductor substrate; and a trench formed in the semiconductor substrate and extending from a surface of the semiconductor substrate to a region within the semiconductor substrate; wherein the trench has dimensions such that the microbe or the virion is trapped within the trench.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: July 13, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Yann Astier, David Esteban, Judson R. Holt, Henry K. Utomo
  • Patent number: 11052224
    Abstract: Apparatuses and methods described herein relate to treating cancerous tumors using radiation therapy and chemotherapy. In some embodiments, a method of treatment includes administering radiation therapy targeting a tumor, isolating a segment of a vessel proximate to the tumor, and administering a dose of a chemotherapeutic agent to the segment of the vessel. The method can further include waiting a period of time after administering the radiation therapy before administering the dose of the chemotherapeutic agent. In some embodiments, a catheter device including first and second occluding elements can be used to isolate the segment of the vessel.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: July 6, 2021
    Assignee: RenovoRx, Inc.
    Inventors: Ramtin Agah, Kamran Najmabadi, Shaun Bagai
  • Patent number: 11052192
    Abstract: This disclosure teaches a disposable inserter which includes a housing having arranged in a displaceable configuration an inserter assembly comprising a cannula assembly with a cannula, a manually operable member for displacing the inserter assembly from a retracted position to an advanced position in order to manually insert the cannula into the skin of a patient, a locking element for blocking or enabling displacement of the inserter assembly, and a coupling arrangement for coupling the disposable inserter to a reusable inserter for automatically displacing the inserter assembly from the retracted position to the advanced position in order to automatically insert the cannula into the skin of the patient.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: July 6, 2021
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Frank Deck, Christian Hoerauf, Ahmet Konya, Thomas Weiss
  • Patent number: 11022664
    Abstract: Systems and methods for transferring fluid to or from a subject use a set of MRI compatible components that can aspirate intrabody structure and/or fluids. The components include a device guide, a semi-rigid guide sheath configured to slidably extend through the device guide, a stylet releasable coupled to the guide sheath and extending a fixed distance out of a distal end thereof, and a cannula coupled to flexible tubing that is releasably interchangeably held in the guide sheath in lieu of the stylet.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: June 1, 2021
    Assignee: ClearPoint Neuro, Inc.
    Inventor: Peter G. Piferi
  • Patent number: 11020536
    Abstract: A manual injection device having a lower body (1) for a reservoir (S), a piston (P) and a needle (A); a movable upper body (2) including a piston rod (TP); and an actuator sleeve (10) including a contact end (11) and movable relative to the lower body between projecting positions and an actuated position. The actuator sleeve (10) is in a first projecting position before the manual injection device is actuated, and in a second projecting position after it is actuated. The actuator sleeve co-operates with the lower body (1) or with any element secured to the lower body to define a pricking lock. The piston rod (TP) co-operates with the reservoir or with an element secured to the reservoir to define an injection lock. The force for actuating the pricking lock is less than the force for actuating the injection lock, such that the pricking lock is actuated first.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: June 1, 2021
    Assignee: APTAR FRANCE SAS
    Inventors: Anthony Saussaye, Quentin Jaouen
  • Patent number: 11013863
    Abstract: The present disclosure pertains to an assembly for a drug delivery device having a housing part, a piston rod displaceable relative to the housing part, a first sleeve member and a second sleeve member. First and second sleeve members are coupled to the housing part. In an initial state of the assembly the first sleeve member is movable from an initial position to a second position relative to the second sleeve member which allows the piston rod to axially travel from an initial position to a predetermined second position such that the assembly is in a primed state. Moreover, in the primed state of the assembly, with the first sleeve member being in the second position relative to the second sleeve member, first and second sleeve members are permanently rotationally and axially locked to each other by a first engagement feature such that first and second sleeve members together form a sleeve.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: May 25, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: David Aubrey Plumptre, Paul Richard Draper, David Richard Mercer, Naceur Rekaya, Paul Griffin
  • Patent number: 10953158
    Abstract: The novel medicament devices comprise a housing that preferably contains a preloaded, conventional syringe with medication. Both trained and untrained users may administer an injection safely and conveniently to themselves or others in myriad settings. Certain of the disclosed embodiments rely on the user's manual action to insert the needle. Only after the needle is fully inserted is the medicament delivered, resulting in a safer injection. After use, the devices include a locking mechanism that locks a spring-loaded sheath in place around the needle for protection. As a common syringe is utilized, engineering and production issues of conventional automatic injectors are avoided.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: March 23, 2021
    Inventors: Steven M. Montgomery, Gregory E. Mote
  • Patent number: 10946146
    Abstract: A syringe driving apparatus includes a housing, a driving member disposed in the housing and a resilient member connected to the housing and the driving member. The housing having a front end, a back end and a compartment between the front end and the back end, the compartment is configured to receive a plunger of the syringe therein. The driving member is movable relative to the housing between the front end and the back end. Movement of the driving member towards the back end deforms the resilient member to store potential energy in the resilient member, and upon release of the potential energy, the resilient member moves the driving member towards the front end to press the plunger to expel medicine out of the syringe.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: March 16, 2021
    Assignee: EPIC MEDICAL PTE. LTD.
    Inventor: Freddie Eng Hwee Lee
  • Patent number: 10940264
    Abstract: Ambulatory infusion pumps, medicament reservoirs, and medicament sealing assemblies, including a variety of trocar seal assemblies and fill plug seal assemblies, plus related components, as well as component combinations and related methods.
    Type: Grant
    Filed: February 12, 2017
    Date of Patent: March 9, 2021
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Roger E. Smith, Tom Xiaobai He
  • Patent number: 10940271
    Abstract: The present specification relates to a syringe comprising a barrel, a plunger moveably arranged within the barrel and a plunger rod for driving the plunger, and a mechanism for providing feedback to a user as the plunger rod is moved relative to the barrel for driving said plunger such that feedback is given to a user as the plunger rod is moved relative to the barrel for driving the plunger. The plunger rod is arranged to drive the plunger such that a predetermined relative movement between at least a portion of the plunger rod and the plunger is allowed. The present specification further relates to a plunger assembly wherein a predetermined relative movement between at least a portion of the plunger rod and the plunger is allowed.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: March 9, 2021
    Assignee: Galderma Holding SA
    Inventor: Anders Holmqvist
  • Patent number: 10933192
    Abstract: Devices and methods for establishing aseptic connections between a drug container and a fluid pathway connection for a drug pump are provided. A fluid pathway connection includes a connection hub, a piercing member, a piercing member retainer, and a drug container. The drug container includes a cap, a pierceable seal, and a barrel. The piercing member is at least partially disposed in a sterile chamber defined by the connection hub, and the connection hub is configured to be connected to the drug container while maintaining an aseptic condition of a fluid pathway from the sterile chamber to an interior of the drug container.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: March 2, 2021
    Inventors: Ian B. Hanson, Lawton Laurence, Antonio Ubach
  • Patent number: 10918766
    Abstract: To provide an agent for hypodermic injection that has excellent flow characteristics, can be used particularly even in thin injection needles, for example with an internal diameter of 0.20 mm or less, and is unlikely to cause pain during injection and inflammation. The agent for hypodermic injection includes a hydrogel containing sintered hydroxyapatite particles, wherein the sintered hydroxyapatite particle content is 1 to 60% by mass based on the total mass of the agent, and the average particle diameter of the sintered hydroxyapatite particles is 15 ?m or less.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: February 16, 2021
    Assignee: Motejo Ltd.
    Inventor: Atsushi Kanauchi
  • Patent number: 10912886
    Abstract: A valve clutch that has a central member extending along a central axis and includes a drive coupler that receives a driving torque. A coupling member is provided that includes coupling pins extending parallel to the central axis. A valve is rotatably disposed around the central axis between inlet and outlet positions. A sleeve is configured to rotationally engage the valve, the sleeve including at least one clamping member. The valve clutch is reversibly changeable between (1) an unengaged configuration wherein a driving torque received by the central member is not transmitted to the sleeve member, and (2) an engaged configuration wherein the at least one coupling pin is clamped between the central member and the at least one clamping member, thereby transmitting the driving torque that is received by the central member via the sleeve member to the valve member.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: February 9, 2021
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Hanspeter Niklaus
  • Patent number: 10898676
    Abstract: A urinary catheter has a tube having a proximal section that is insertable into a urethra and a distal section having a connector secured to a distal end of the tube. A lumen is formed longitudinally in the tube and a hydrophilic coating applied to an exterior surface of the tube. The proximal section of the tube includes a proximal tip end that is closed to terminate the lumen at the proximal tip end, with the proximal tip end rounded for insertion of the proximal tip end through the urethra and into a bladder. The proximal section of the tube is conical such that a first outer diameter of the proximal section of the tube measured at the proximal tip end is smaller than a second outer diameter of the proximal section of the tube measured distal from the proximal tip end.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: January 26, 2021
    Assignee: Coloplast A/S
    Inventors: Egon Triel, Johnny Wagner
  • Patent number: 10869670
    Abstract: A method of resecting entire layers of a digestive tract includes: an insertion step of inserting an endoscope into the digestive tract; an everting step performed after the insertion step, to suture mucosal layers located on both sides of a target region including a lesion, cover the target region with the mucosal layers, and evert a tract wall including the target region to a side of an abdominal cavity, in the digestive tract; and an incision step performed after the everting step, to position an incision tool between the target region and the mucosal layers to incise the tract wall around the lesion by the incision tool.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: December 22, 2020
    Assignee: OLYMPUS CORPORATION
    Inventor: Osamu Goto
  • Patent number: 10857302
    Abstract: A syringe carrier for use within an automatic injection device includes a substantially tubular body having a first end, a middle portion, and a second end, configured to contain a portion of a syringe and displace the syringe within a housing of the automatic injection device from a first position to a second position; a first pair of legs defining at least a portion of a front opening in the substantially tubular body proximal to the first end; a second pair of legs defining at least a portion of a rear opening in the substantially tubular body proximal to the first end; and a syringe carrier coupler having a first beam and a second beam extending from the middle portion partially beyond the first pair of legs at the first end of the substantially tubular body.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: December 8, 2020
    Assignee: AbbVie Inc.
    Inventors: Sherwin S. Shang, Joseph F. Julian, Chuan Li, Eduard N. Tsvirko, Edwin Chim, Shubha Chethan Somashekar, Esra Ozdaryal
  • Patent number: 10850037
    Abstract: An injector may include a container having a wall with an interior surface defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a sterile container needle that is in fluid communication with the container in a delivery state, but may or may not be in fluid communication with the container in a storage state. Further, the injector may include an actuator that is adapted to move the container needle from the storage state to the delivery state.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: December 1, 2020
    Assignee: AMGEN INC.
    Inventor: Scott R. Gibson
  • Patent number: 10843213
    Abstract: A fluid management system includes an authentication device and a fluid dispensing meter, and the fluid dispensing meter includes a processor and a memory. The authentication device is configured to provide data to the processor. The processor is configured to recall information from the memory, to compare the information to the data received from the authenticator, and to control a trigger control mechanism between the activated state and the deactivated state based on the comparison.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: November 24, 2020
    Assignee: Graco Minnesota Inc.
    Inventors: Bradley G. Kahler, Mark L. Bauck, Joshua R. Holmstadt, Glenn E. Highland, Benjamin J. Paar, Chad G. Igo
  • Patent number: 10835689
    Abstract: Methods of protecting muscle tissue from heterotopic ossification employ targeted deliveries of a neuromuscular inhibitor. A method of protecting muscle tissue from heterotopic ossification includes identifying a volume of muscle tissue that is susceptible to heterotopic ossification. A first aliquot of a therapeutic dose of a neuromuscular inhibitor is delivered at a first delivery site within the volume of muscle tissue. A second aliquot of the therapeutic dose is delivered at a second delivery site within the volume of muscle tissue. The first and second delivery sites are separated by a distance to distribute the therapeutic dose within the targeted volume of muscle tissue.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: November 17, 2020
    Assignee: UNIVERSITY OF WASHINGTON
    Inventors: Brandon J. Ausk, Steven Bain, Ted S. Gross
  • Patent number: 10828235
    Abstract: A syringe includes a syringe body having a syringe barrel for receiving and administering a medicament, a hollow needle fluidly communicating with the syringe barrel, and a needle adapter disposed on the syringe body. An outer diameter of the needle adapter is wider than an outer diameter of the syringe barrel, and a distal surface of the needle adapter is substantially flat. The needle adapter facilitates a flush alignment of the distal surface of the needle adapter with at least one of a vial stopper and a vial stopper holder of a medicament vial to ensure that a tip of the needle is properly inserted into the vial to aspirate the medicament within the vial.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: November 10, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Amit Limaye, Kevin O'Hara, David Schiff, Jesse Gala
  • Patent number: 10814061
    Abstract: An infusion set is disclosed that includes an inserter including an inserter housing having at least one flexible arm for holding an infusion set in a single axial position prior to insertion of at least a portion of a cannula of the infusion set, the inserter housing having a surface for contacting the patient's skin. The inserter also includes a movable plunger disposed within the inserter housing for releasing the infusion set from the inserter housing, impacting the infusion set, and imparting momentum to the infusion set to insert the cannula into the patient's skin. The inserter additionally includes a biasing element biasing the plunger toward the activated position.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: October 27, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Eric Bene, Russell Cole, Arthur Klotz, Melissa Rosen, Judy Lin Walish, Michel Bruehwiler, Michael Creighton
  • Patent number: 10814116
    Abstract: A hollow needle device includes a main body having a first surface on which hollow acicular bodies are formed and a second surface opposite to the first surface, a main body supporting member having an opening that accommodates the main body and including a drop-out prevention mechanism for holding the main body that has the hollow acicular bodies being protruded from one end of the opening, an injector supporting member disposed detachably in the opening of the main body supporting member, and a liquid-tight structure that establishes liquid tightness between the injector supporting member and an inner surface that defines the opening in the main body supporting member. The injector supporting member has a connection hole to which a protrusion of an injector is detachably connected liquid tightly to guide an injection solution supplied from the injector into the opening via the protrusion of the injector.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: October 27, 2020
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventor: Tomoya Sumida
  • Patent number: 10799635
    Abstract: The present disclosure relates to a monitoring unit for a medicament delivery device, where the monitoring unit has a housing, monitoring circuit arranged in the housing, capable of detecting and monitoring functions of the medicament delivery device, releasable holding elements, which releasable holding elements interact with a medicament delivery device for releasably holding the monitoring unit when attached to a medicament delivery device. Locking elements are operably arranged in the monitoring unit to act on the attachment mechanism, and at least one drive element is operably connected to the locking elements wherein, upon activation of the monitoring unit, the at least one drive element causes the locking elements to act on the releasable holding elements, preventing detachment of said monitoring unit from the medicament delivery device.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: October 13, 2020
    Assignee: SHL MEDICAL AG
    Inventors: Daniel Carlsson, Daniel Säll, Nikolaj Hautaviita
  • Patent number: 10780226
    Abstract: A trigger assembly for an automatic medication injection device. The trigger assembly includes an actuator that rotates when shifted axially, and at least one upstanding member extending from a biased drive element of the device toward said actuator which is rotated within the device housing when the actuator is shifted axially. The trigger assembly also includes a track and follower structured and arranged to guide the biased drive element when being rotated within said housing when the actuator shifts axially and to release the biased drive element for axial movement.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: September 22, 2020
    Assignee: Eli Lilly and Company
    Inventors: Nicole Taylor Gonzalez, Gregory Alan Musselman, Lisa Jeanne Nelson
  • Patent number: 10780219
    Abstract: Ambulatory infusion pumps, medicament reservoirs, and medicament sealing assemblies, including a variety of trocar seal assemblies and fill plug seal assemblies, plus related components, as well as component combinations and related methods.
    Type: Grant
    Filed: February 12, 2017
    Date of Patent: September 22, 2020
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Roger E. Smith, Tom Xiaobai He
  • Patent number: 10773021
    Abstract: The present invention relates to a shell assembly for a medicament delivery device, which shell assembly comprises at least one first shell section provided with an entry passage and designed such that at least a major part of a medicament delivery device entered through said entry passage is accommodated inside said at least one first shell section, a closure element operably arranged to said at least one first shell section for closing said entry passage, and fixation elements arranged for fixating said medicament delivery device in relation to said at least one first shell section and said closure element.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: September 15, 2020
    Assignee: SHL MEDICAL AG
    Inventors: Wen-An Chang, Hsueh-Yi Chen, Chia-Hsin Su
  • Patent number: 10758684
    Abstract: A tamper evident assembly for retaining a plunger and piston within a barrel of a syringe including an elongated tether and a cover connected to the tether and concurrently disposed in an operative position on the syringe. A connector assembly adjustably and fixedly interconnects the tether to the cover in the operative position, wherein the cover is connected in covering relation to a discharge port of the syringe concurrently to a proximal end of the tether being connected to the syringe barrel in a removal preventative relation to the piston. Movable adjustment of the tether relative to the connector assembly defines a retaining segment disposed into a taut, fixed length orientation between the proximal end of the tether and the cover, to further define the operative position.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: September 1, 2020
    Inventors: Jonathan J. Vitello, Timothy Brandon Hunt, Robert Banik
  • Patent number: 10751458
    Abstract: A displacement sensing device is configured for a peritoneal dialysis system. The peritoneal dialysis system includes a housing and a syringe. The syringe is disposed on the housing and has a push rod. The displacement sensing device includes a guide rod, a probing module, and a resistance scale. The guide rod is coupled to the push rod, and the probing module is disposed in the housing and is fixed at the guide rod. The resistance scale is disposed at a side of the probing module. The probing module is configured to contact the resistance scale to obtain a resistance value of the resistance scale and determine a displacement magnitude of the push rod. In addition, a peritoneal dialysis system is also mentioned.
    Type: Grant
    Filed: January 14, 2018
    Date of Patent: August 25, 2020
    Assignees: Acer Incorporated, BENEPET CO., LTD.
    Inventors: Chun-Hung Wen, Wei-Chen Lai, Pu-De Ciou, Wen-Pin Chang, Tsung-Hsun Wu, Wen-Shu Lee, Ta-Lun Tan
  • Patent number: 10737021
    Abstract: Disclosed is a medical system having a cartridge and an inserter. The cartridge includes a housing having an interior volume with a first guide within the interior volume. A cradle is disposed within the interior volume and is configured for mounting a medical appliance. The cradle includes a subcutaneous element and an insertion needle. The insertion needle is configured for being actuated to insert the subcutaneous element into a subject. The inserter includes a second guide configured to mate with the housing of the cartridge, and the first guide and second guide are configured to cooperate to guide the inserter into the interior volume along a guiding path defined by the first guide. The inserter is configured to removably attach to the cradle when guided into the interior volume. An insertion assembly is provided for actuating the insertion needle to insert the subcutaneous element into the subject.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: August 11, 2020
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Frank Deck
  • Patent number: 10722660
    Abstract: There is disclosed a fluid warming system (300) for warming intravenous fluid, comprising: a heater unit (304), including a heating element (314) and at least one temperature sensor; a heat exchanger unit (302), removably attachable to the heater unit (304), which includes an inlet (306) and an outlet (308) through which the fluid can pass, and a controller (316), programmed: to receive at least one temperature measurement (TCI, TCO) from said at least one temperature sensor in the heater unit (304); to compute a fluid flow rate (q), corresponding to the rate of flow of fluid from the inlet (306) to the outlet (308) of the heat exchanger unit (302), in dependence on the amount of electrical power (PH) supplied to the heating element and said at least one temperature measurement (TCI, TCO); and to control the electrical power (PH) supplied to the heating element in dependence on the computed fluid flow rate (q).
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: July 28, 2020
    Assignee: THE SURGICAL COMPANY INTERNATIONAL B.V.
    Inventor: Robertus Gerardus Van Oudenallen
  • Patent number: 10722646
    Abstract: A cannula insertion device is disclosed. The device includes a needle carriage, a rail device on which the needle carriage is slidable, a yoke having a channel, a linkage connected to the needle carriage and extending into the channel, a torsion spring with one end connected to the linkage, and locking device for locking the torsion spring in tension and maintaining the needle carriage and the linkage in a locked position prior to activation. Upon release of the locking device, the tension of the torsion spring is released, which causes the linkage to move in the channel and slide the needle carriage along the rail device. A catheter carriage may also be provided for actuation by the linkage.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: July 28, 2020
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Russell Cole, Alyssa Jackson
  • Patent number: 10716926
    Abstract: A microneedle injection and infusion apparatus, and a method of using same. The apparatus can include a housing, a microneedle array holder for holding a microneedle array, and a shuttle that holds a cartridge (e.g., that contains an active agent). The microneedle array holder can be movable between a retracted position and an extended position. The shuttle can be movable between a first position in which the cartridge is not in fluid communication with a fluid path and a second position in which the cartridge is in fluid communication with the fluid path. The apparatus can further include an actuator movable between a first position and a second position. The method can include moving the actuator to its second position to allow the shuttle to move toward its second position, wherein movement of the shuttle toward its second position allows the microneedle array holder to move to its extended position.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: July 21, 2020
    Assignee: Kindeva Drug Delivery L.P.
    Inventors: Scott A. Burton, Chin-Yee Ng, Michael J. Frits, Richard R. Mathias