With Expanding Member (i.e., Balloon) Patents (Class 604/509)
  • Patent number: 11547836
    Abstract: A coaxial stabilizing and sealing catheter provides increased support to a guide catheter that is seated in an ostium of a branch artery by extending through and out of a distal end of the guide catheter and anchoring in position within the branch artery that is being treated. The stabilizing and sealing catheter includes, as part of a relatively flexible distal section, a balloon that locks a distal end of the stabilizing and sealing catheter in place to provide support to therapeutic devices that are introduced and further seals the branch artery to prevent blood from entering the branch artery. A sealing cuff at a proximal end of the stabilizing and sealing catheter provides a seal between an exterior of the stabilizing and sealing catheter and an interior of the guide catheter. In addition, a fixing mechanism is utilized to lock the guide catheter in place to exchange therapeutic devices.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: January 10, 2023
    Assignee: Radius Medical LLC
    Inventors: David Daniels, Richard M. DeMello, Maureen A. Finlayson, Jonathan R. DeMello
  • Patent number: 11534575
    Abstract: A system of devices for treating an artery includes an arterial access sheath adapted to introduce an interventional catheter into an artery and an elongated dilator positionable within the internal lumen of the sheath body. The system also includes a catheter formed of an elongated catheter body sized and shaped to be introduced via a carotid artery access site into a common carotid artery through the internal lumen of the arterial access sheath. The catheter has an overall length and a distal most section length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.
    Type: Grant
    Filed: May 19, 2022
    Date of Patent: December 27, 2022
    Assignee: Route 92 Medical, Inc.
    Inventors: Michi E. Garrison, Tony M. Chou
  • Patent number: 11529440
    Abstract: Embodiments of the invention include drug delivery coatings and devices including the same. In an embodiment, the invention includes a drug delivery coating including a polymeric layer. The polymeric layer can include a hydrophilic outer surface. The coating can also include a matrix contacting the hydrophilic outer surface. The matrix can include a particulate hydrophobic therapeutic agent and a cationic agent. The polymeric layer can further include a hydrophilic polymer having pendent photoreactive groups and a photo-crosslinker including two aryl ketone functionalities. Other embodiments are also included herein.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: December 20, 2022
    Assignee: Surmodics, Inc.
    Inventors: Joram Slager, Toni M. Heyer, David E. Babcock
  • Patent number: 11529190
    Abstract: A medical instrument for enhancing diagnosis and treatment comprising a handle, an ablation probe extending from the handle, a catheter extending from the handle. The catheter defines a lumen and the ablation probe is located within the lumen of the catheter. A port in fluid communication with the lumen of the catheter is configured for connection to a vacuum or fluid source, and application of a vacuum or an injection of fluid creates a consistent zone of permittivity around the ablation probe.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: December 20, 2022
    Assignee: COVIDIEN LP
    Inventor: William S. Krimsky
  • Patent number: 11517338
    Abstract: A catheter comprises an elongated carrier and a balloon carried by the carrier in sealed relation thereto. The balloon has an outer surface and is arranged to receive a fluid therein that inflates the balloon. The catheter further comprises a shock wave generator within the balloon that forms mechanical shock waves within the balloon, and a medicinal agent carried on the outer surface of the balloon. The medicinal agent is releasable from the balloon either before or in response to the shock wave.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: December 6, 2022
    Assignee: SHOCKWAVE MEDICAL, INC.
    Inventor: Daniel Hawkins
  • Patent number: 11491306
    Abstract: The present disclosure provides an apparatus including a first tubular housing including a first exit port and a second tubular housing including a second exit port. The apparatus also includes a third tubular housing coupled to at least one of the first tubular housing and the second tubular housing such that each of the first tubular housing, the second tubular housing, and the third tubular housing are fixed with respect to one another. The apparatus also includes a first catheter including a first plurality of outlets and is configured to be positioned at least partially within the first tubular housing. The apparatus also includes a second catheter including a second plurality of outlets and is configured to be positioned at least partially within of the second tubular housing. The apparatus also includes a pressure transducer line positioned in the third tubular housing and a pressure transducer coupled to the pressure transducer line.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: November 8, 2022
    Assignee: Sanford Health
    Inventors: Patrick W. Kelly, Joel M. Wasdyke, Roger W. McGowan, Patrick A. Haverkost, Alex James Wiedmann
  • Patent number: 11478248
    Abstract: The present invention provides a percutaneous vascular surgical system for performing endovascular/neurovascular interventions, the system incorporating a sheath having a proximal end and a distal end and defining a main lumen extending between the proximal and distal ends, an auxiliary lumen also defined by the sheath, a reversibly inflatable balloon located about the sheath adjacent the distal end and in fluid communication with the auxiliary lumen, a syringe selectively connectable to the main lumen to create suction through the main lumen, and a vessel closure device for the closure of the arteriotomy, the surgical system and method of the invention having utility in a large number of percutaneous vascular procedures such as carotid artery stenosis or neurovascular interventions and enabling four procedures to be performed with one system, being percutaneous access, emboli removal, flow reversal and arteriotomy closure.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: October 25, 2022
    Assignee: National University of Ireland, Galway
    Inventors: Sherif Sultan, Niamh Hynes, Robert Miculas, Stefan Lohfeld, Colin Henehan
  • Patent number: 11433160
    Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: September 6, 2022
    Assignees: TEIJIN LIMITED, KM BIOLOGICS CO., LTD.
    Inventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
  • Patent number: 11406404
    Abstract: Provided herein are methods for protecting distal vessels from emboli during aspiration, the method comprising delivery and deployment of an emboli protection device which is advanced and placed distally relative to the clot burden and thus deep in the neurovascular bed until the device, once deployed, fully opposes a vessel wall creating a circumferential seal across the vessel. The methods utilizing the emboli protection device protect distal vasculature from vulnerable clot emboli which become dislodged during clot removal and/or aspiration and trapped in the emboli protection device.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: August 9, 2022
    Assignee: Cerus Endovascular Limited
    Inventor: Stephen Griffin
  • Patent number: 11383090
    Abstract: A pacemaker fixation system, a leadless pacemaker system and a method of use thereof are disclosed. The leadless pacemaker system includes: a pacemaker fixation system including a leadless pacemaker and an elastic unfoldable element attached thereto, wherein in an unfolded configuration of the elastic unfoldable element, it fixes the leadless pacemaker at a target location in a blood vessel in communication with the heart; a delivery system for delivering the pacemaker fixation system to the target location; and a guide for guiding the delivery system into the blood vessel. According to the present invention, atrial pacing can be achieved by the leadless pacemaker through fixing the leadless pacemaker in the blood vessel in communication with the heart with the elastic unfoldable element.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: July 12, 2022
    Assignee: MICROPORT SOARING CRM (SHANGHAI) CO., LTD.
    Inventors: Zhijun Cheng, Grace Ying Yang Jang, Li Wang, Jiangkai Sun
  • Patent number: 11291471
    Abstract: A medical system comprising a guiding catheter having an inflation lumen. The inflation lumen extends within a handle and a shaft of the guiding catheter. An inflatable sleeve has a proximal end and a distal end, with the ends attached to the guiding catheter. A sealed interior portion of the inflatable sleeve is bounded by the inflatable sleeve and the shaft of the guiding catheter, and in fluid communication with a distal port of the inflation lumen. The system further comprises a delivery catheter defining a delivery lumen and configured for sliding engagement within the guide lumen of the guiding catheter.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: April 5, 2022
    Assignee: Medtronic, Inc.
    Inventors: Andrea J. Asleson, Teresa A. Whitman, Kelly M. Wien
  • Patent number: 11285254
    Abstract: The present invention provides a method, system, and apparatus that can substantially reduce the recirculation of venovenous extracorporeal membrane oxygenation (VV ECMO) associated with the two-site, single-lumen cannulation approach. Actively-controlled flow regulators comprising balloon, occluder and reservoir can be individually or collectively equipped on the drainage and/or infusion cannulas to accomplish the goal of maximizing VV ECMO support efficacy. Three specific embodiments are introduced to illustrate the practical enforcement of the proposed blood flow control in reference to the heart rhythm, aiming at achieving the maximal reduction of oxygenated blood flow recirculating back to the VV ECMO circuit.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: March 29, 2022
    Assignee: 3R Life Sciences Ltd.
    Inventors: Pong-Jeu Lu, Hsiao-Chien Lin
  • Patent number: 11288811
    Abstract: A method, apparatus and device for correcting a vascular pressure difference are disclosed. An intracavity imaging technology is used to acquire images in a main branch blood vessel. A plurality of blood vessel cross sections are obtained using the images, and an area of a cutting plane of a side branch blood vessel is directly calculated by using the blood vessel cross sections. The blood vessel difference is then corrected by using the cutting area.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: March 29, 2022
    Inventors: Shengxian Tu, Wei Yu, Jiayue Huang, Yundai Chen, Fuhua Yan
  • Patent number: 11278388
    Abstract: A catheter device is disclosed comprising; an elongate sheath (503) with a lumen and a distal end for positioning at a heart valve (6), an embolic protection device (200) for temporarily positioning in the aortic arch for deflection of embolic debris from the ascending aorta to the descending aorta, said embolic protection device is connectable to a transluminal delivery unit (130) extending proximally from a connection point (131), and having: a frame with a periphery, a blood permeable unit within said periphery for preventing embolic particles from passing therethrough with a blood flow downstream an aortic valve into side vessels of said aortic arch to the brain of a patient, and at least one tissue apposition sustaining unit (300, 350) extending from said catheter, into said aortic arch, and being attached to said embolic protection device at a sustaining point (502), for application of a stabilization force offset to said connection point at said embolic protection device, such as at said periphery, and
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: March 22, 2022
    Assignee: SWAT Medical AB
    Inventor: Erik Krahbichler
  • Patent number: 11253287
    Abstract: A device and method for establishing retrograde blood flow during recanalization of a vessel having a targeted blockage. While in a collapsed state an occluding component is introduced distally intravascularly traversing the targeted blockage to its distal side. Then, the occluding component transitions to an expanded state having an enlarged diameter forming a seal with an internal wall of the vessel prohibiting anterograde blood flow beyond the expanded occluding component. Retrograde blood flow is thereby established in a region of the vessel bound at one end by the occluding component and at an opposite end by the targeted blockage by dispensing a flushing fluid into the region of the vessel.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: February 22, 2022
    Assignee: NEURAVI LIMITED
    Inventor: Ray McCarthy
  • Patent number: 11224435
    Abstract: Closure devices and methods for ligating tissue, such as the left atrial appendage, generally, include an elongate body having a first lumen therethrough, a snare loop assembly, a vacuum tube, and an imaging device. The snare loop assembly may include a snare and a suture loop releasably coupled to the snare and may at least partially extend from a distal end of the elongate body. The vacuum tube may be slidably positioned within the first lumen to extend through the snare loop assembly. The imaging device may be disposed within the lumen of the vacuum tube.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: January 18, 2022
    Assignee: SentreHEART LLC
    Inventors: Gregory W. Fung, Robert L. Clark, III, Russell A. Seiber, Russell Pong, Arnold M. Escano
  • Patent number: 11197982
    Abstract: A balloon catheter is disclosed for endovascular procedures. In one embodiment, among others, the balloon catheter includes an elongated catheter body. At a distal end, the catheter body also includes an angled tip and a balloon adjacent to the angled tip. The balloon is inflatable to form an oblong shape.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: December 14, 2021
    Inventor: David Sharpe Heister
  • Patent number: 11154690
    Abstract: The present invention provides for devices and methods for providing endovascular therapy, including facilitating establishment of vascular access, placement of endovascular sheaths, catheter tip localization, and administration of vascular occlusion. The invention includes a vessel cannulation device, an expandable sheath, an occlusion catheter, and a localizer each of which may be provided separately or used as part of a system. One embodiment of the invention is a vessel cannulation device including: a housing having a distal end with a distal tip and a proximal end; a guidewire lumen passing through the housing and at least the distal tip; a sensor coupled to the guidewire lumen; and an advancing member, which is configured for advancing at least one of a guidewire or a sheath and which is operably coupled to the sensor.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: October 26, 2021
    Assignee: TRAUMATEK SOLUTIONS, B.V.
    Inventors: Itzhak Avneri, Ben-Ami Avneri, Shahar Avneri, Lior Avneri
  • Patent number: 11135077
    Abstract: Methods of reducing air within a stent graft delivery device are disclosed, utilizing various flushing techniques. A port in a manifold that includes a pusher catheter coaxially disposed about a guide wire catheter is flushed. A portion in a sheath hub that excludes a longitudinally extended outer sheath coaxially disposed about the pusher catheter is flushed with a flushing fluid and/or a blood soluble gas, such as carbon dioxide. The guide wire catheter is also flushed.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: October 5, 2021
    Assignee: Cook Medical Technologies LLC
    Inventors: Jarin A. Kratzberg, Blayne A. Roeder, Erik E. Rasmussen, Tilo Kölbel
  • Patent number: 11134965
    Abstract: The present disclosure describes effector deployment systems and devices that can be coupled adjunctively to a shaft of a concentric cylinder system, to provide additional functionality during intravascular procedures.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: October 5, 2021
    Assignee: Asia Pacific Medical Technology Development Company, Ltd
    Inventor: John R. Gilbert
  • Patent number: 11058855
    Abstract: Methods and devices quickly and accurately locate the sphenopalatine ganglion (SPG) while performing a sphenopalatine ganglion block procedure that introduces a medication to the SPG. The methods and devices also prevent the medication applied to the SPG from flowing down a patient's throat during the procedure.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: July 13, 2021
    Assignee: BIOVISION TECHNOLOGIES, LLC
    Inventors: Stephen W. Chandler, David W. Sanso
  • Patent number: 11026719
    Abstract: An introducer sheath may include a tubular member comprising an inner layer and an outer layer coaxially disposed about a central longitudinal axis of the introducer sheath, the tubular member being configured to shift between an unexpanded configuration to an expanded configuration. The inner layer may be circumferentially discontinuous along at least a portion of its length. At least a first portion of the inner layer may be configured to move circumferentially relative to the outer layer when shifting between the unexpanded and expanded configurations.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: June 8, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Michael Richmon Thoreson, Adam David Grovender, Scott Solberg, David Raab, Benjamin Philip Gundale, Ross A. Olson, James M. Anderson
  • Patent number: 10980985
    Abstract: The invention provides a catheter and control box apparatus and related methods that are useful in delivering liquids, including liquids comprising nucleic acid molecules into cells. In particular, the invention provides a catheter that stabilizes fluid flow within a vein to deliver a volume, pressure charge of saline solution, exogenous compositions, and isolated vectors to kidney cells, using the renal vein as a guide and under hydrodynamic pressure. The catheter and control box apparatus and related methods described herein are useful to research, prognose, ameliorate symptoms of kidney injury, and treat kidney pathologies.
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: April 20, 2021
    Assignees: Indiana University Research and Technology Corporation, United States Government as Represented by the Department of Veterans Affairs
    Inventor: Robert Bacallao
  • Patent number: 10966726
    Abstract: A balloon assist device is disclosed which includes an inner body, a balloon joined to the inner body, and a positioner. The inner body includes an open-ended closed tube extending along an axis from a proximal end to a distal end. The balloon assist device also includes an inflation tube in sealed communication with the balloon. The positioner allows a clinician to slide the balloon assist device along the catheter. The positioner may also include the inflation tube.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: April 6, 2021
    Assignee: DePuy Synthes Products, Inc.
    Inventor: Juan Lorenzo
  • Patent number: 10940287
    Abstract: An exemplary catheter can be provided which can include, for example, a first inflation arrangement configured, in operation, to substantially seal and/or anchor the catheter inside the bladder when inflated, a second inflation arrangement configured, in operation, to substantially float in urine when inflated, wherein the second arrangement can be located at a predetermined distance from the first inflation arrangement, and an aperture provided between the first inflation arrangement and the second inflation arrangement, where the first and second arrangements can cause the aperture to be (i) open when the second inflation arrangement can be located at a first position relative to the first inflation arrangement, and (ii) closed when the second inflation arrangement can be located at a second position relative to the first inflation arrangement, and where the second position can be different than the first position.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: March 9, 2021
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Nicola J. Nasser, Michael J. Zelefsky
  • Patent number: 10932797
    Abstract: A method of removing vascular blockage includes providing a catheter system, comprising an outer catheter, a bypass catheter, and a guidewire. In the catheter system, the bypass catheter is slidably disposed within the outer catheter. The method includes positioning a distal end of the catheter system at a proximal end of an occlusion located within a vessel and moving the bypass catheter through the occlusion so that a medicated treatment solution may be delivered through the bypass catheter to an area of the brain or other tissue served by the vessel blocked by the occlusion. Both during and after the delivery of medicated treatment solution to the blocked part of the vessel with the bypass catheter, the physician may engage the occlusion with the perforated segment of the outer catheter so that a thrombolytic agent can be delivered at the occlusion to disintegrate it and then removing at least a portion of the occlusion from the vessel.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: March 2, 2021
    Inventor: Jeffrey E. Thomas
  • Patent number: 10933171
    Abstract: Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: March 2, 2021
    Assignees: Tokyo Metropolitan Industrial Technology Research Institute, National University Corporation Gunma University
    Inventors: Toshio Uraoka, Naohisa Yahagi, Shunji Yunoki, Yoshimi Ohyabu, Takefumi Narita
  • Patent number: 10918840
    Abstract: Active Energy Facilitated Drug Delivery platform for delivering therapeutics to biological tissue through electrical conductivity. This delivery method is comprised of an elastic alloy to encase a balloon or drug deposition, where the alloy acts to emit an electric field in aiding and actively allowing the pharmaceutical agent to have enhanced permeation, binding and internalization to cells and the biological matrix. A therapeutic agent is deposited onto a balloon to embody the drug deposition, reservoir whereby the electrical field facilitates the active transfer of a pharmaceutical agent to the target tissue is described.
    Type: Grant
    Filed: April 4, 2015
    Date of Patent: February 16, 2021
    Assignee: Hydra Vascular LLC
    Inventor: Douglas Phat Hatran
  • Patent number: 10912938
    Abstract: The disclosure relates to a multipolar, detection/stimulation endovascular lead intended to be implanted in the coronary venous network. The lead comprises a lead body with in proximal portion a connector to a cardiac pacemaker/defibrillator generator, and in a distal portion a first branch and a second branch extending beyond a bifurcation. The distal ends of the branches are free ends carrying an array of electrodes connected to the connector. Each of the branches comprises at its free end an outlet in the distal direction, able to receive an implantation guide wire inserted therein and to guide the implantation guide wire in an axial direction parallel to the main axis of the lead body.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: February 9, 2021
    Assignee: Sorin CRM SAS
    Inventor: Jean-François Ollivier
  • Patent number: 10898694
    Abstract: A device and system for thermally affecting tissue that includes a balloon catheter with a reduced distal length for ease of navigation and that also includes a balloon that is more resistant to bursting and delamination. The balloon may include a proximal neck generally attached to an elongate body and a distal neck generally attached to a shaft disposed within the elongate body. The distal neck is turned inward to extend within the balloon chamber and the proximal neck may either extend within the chamber or extend proximally away from the balloon chamber. Alternatively, the device may include an inner balloon and an outer balloon, the distal necks of both being turned inward and extending within the inner balloon chamber. The proximal necks may both also be turned inward to extend within the chamber or the proximal neck of the outer balloon may extend away from the balloon chamber.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: January 26, 2021
    Assignee: Medtronic CryoCath LP
    Inventor: Jean-Pierre Lalonde
  • Patent number: 10888414
    Abstract: A system for treating aortic dissection including an aortic dissection implant comprising an expandable anchoring structure and an elongate tubular structure. The expandable anchoring structure can be configured to apply radial force to the sinuses of the aortic root and/or the sinotubular junction when expanded. The elongate tubular structure can comprise an expandable support frame and one or more layers. The expandable support frame can be configured to extend from the descending aorta to the ascending aorta and curve along with a curvature of the aortic arch when expanded within the aorta. The one or more layers can comprise a first porous layer comprising an atraumatic outer surface positioned over the expandable support frame and a second non-porous layer positioned over a portion of the first porous layer. The second non-porous layer may be configured to be positioned on opposite sides of the aortic dissection and to be inflatable via blood flow to seal against the dissection.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: January 12, 2021
    Assignee: inQB8 Medical Technologies, LLC
    Inventors: Arshad Quadri, J. Brent Ratz, Christopher William Stivers
  • Patent number: 10874376
    Abstract: An endobronchial probe includes a deflector having a bore extending therethrough at an angle to its long axis for passage of a tool. The probe includes a location sensor and an ultrasound imager. A push-pull anchoring system comprises a plurality of guides and wires that can extend beyond the guides and retract within the guides. When extended the wires diverge from the long axis sufficiently to engage a bronchus. The probe includes a balloon disposed on the distal segment contralateral to bore that when inflated urges the mouth of the bore into contact with the bronchial wall.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: December 29, 2020
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Jonathan Reuben Waldstreicher, William Sanford Krimsky, Yitzhack Schwartz, Avi Shalgi, Meir Bar-Tal, Matityahu Amit, Gal Hayam, Refael Itah, Robert D. Ainsworth
  • Patent number: 10874839
    Abstract: An apparatus includes a body, a shaft assembly, a deflection actuation assembly, and a dilation catheter. The shaft assembly includes a rigid proximal portion and a flexible distal portion. The deflection actuation assembly includes a rotary actuator and a first translatable actuation member at least partially disposed within the first rotary actuator. A second translatable actuation member extends through the shaft assembly and couples the first translatable actuation member with the flexible distal portion of the shaft assembly. The first rotary actuator is rotatable about a longitudinal axis to thereby drive the first and second translatable actuation members longitudinally. The flexible distal portion is configured to deflect away from the longitudinal axis in response to translation of the first and second translatable actuation members longitudinally. The dilation catheter is slidable relative to the shaft assembly and includes an expandable dilator.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: December 29, 2020
    Assignees: Acclarent, Inc., Biosense Webster (Israel) Ltd.
    Inventors: George L. Matlock, Yehuda Algawi, Ilya Sitnitsky, Andres C. Altmann, Ygal Zucker, Don Q. Ngo-Chu, Vadim Gliner, Christopher T. Beeckler, John H. Thinnes, Jr., Assaf Govari
  • Patent number: 10869633
    Abstract: An intravascular sensor assembly including a flexible elongate member having a longitudinal axis (LA) is provided. The sensor assembly includes a first engagement feature proximal to a distal end of the flexible elongate member; a core member disposed inside a lumen of the flexible elongate member, the core member configured to translate within the flexible elongate member along the LA proximal to the first engagement feature; and a component holding a sensor circuit, the component fixedly secured to a distal end of the core member such that the mounting structure translates along the LA of the flexible elongate member with the core member. A system and a method for performing measurements using a sensor as above are also provided.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: December 22, 2020
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventor: David H. Burkett
  • Patent number: 10864046
    Abstract: A system includes a dilation catheter and a guide member. The dilation catheter includes a proximal end, a distal end, a dilator, a navigation sensor, and a force sensor. The dilator is positioned proximal to the distal end and is configured to transition between a non-dilated configuration and a dilated configuration. The navigation sensor is positioned distal to the dilator and is configured to cooperate with a guidance system and thereby provide signals indicating a position of the dilation catheter in three-dimensional space. The force sensor is positioned distal to the dilator and is configured to provide signals indicating a force encountered by the force sensor. The dilation catheter is configured to slide relative to the guide member. A distal portion of the guide member is sized and configured to fit in a nasal cavity of a patient.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: December 15, 2020
    Assignee: Acclarent, Inc.
    Inventors: Henry F. Salazar, Jetmir Palushi, David A. Smith, Jr.
  • Patent number: 10857328
    Abstract: An innovative medical device that permits rapid, minimally invasive restoration of blood flow across a vascular blockage. A system allowing for lysis or removal of said blockage. Said device creates a temporary bypass using longitudinal structure configured for insertion into the blood vessel and adapted to deliver a side hole to a target area. The side hole defines a distal first segment and a proximal second segment with a lumen to allow blood flow therethrough to the distal end hole. In an alternate embodiment, a slidable outer sheath can cover the side hole to permit reversal of blood flow from the distal end hole to a proximal end hole located outside a patient's body by means of an aspiration controller. Alternate embodiments include an optional anchoring balloon, a macerating stent or wires, perforations for fluid delivery, and an backflow valve.
    Type: Grant
    Filed: January 16, 2018
    Date of Patent: December 8, 2020
    Inventor: Daniel Ezra Walzman
  • Patent number: 10849730
    Abstract: Various implementations of a percutaneous transluminal angioplasty device include a catheter, a filter, and an expandable balloon. The filter is coupled adjacent a distal end of the catheter and is movable between an unexpanded and expanded configuration via a filter activation wire extending through a lumen of the catheter. An anti-stenotic therapeutic agent is disposed on an outer surface of the balloon, and the balloon is disposed on the catheter proximally of the filter. An axial movable sheath is positioned over the balloon and filter during deployment to a target site and is axially retracted away from the filter and balloon prior to treatment of a lesion. At the target site, the exposed filter is expanded via the filter activation wire. Then, the exposed balloon is inflated to dilate and deliver the therapeutic agent to the lesion.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: December 1, 2020
    Assignee: Contego Medical, Inc.
    Inventors: Ravish Sachar, Eugene Serina, Dave Stern
  • Patent number: 10842972
    Abstract: Described herein are methods and devices for delivering a drug to the frontal sinus system. An inflatable implant is positioned within the frontal sinus system using an anchoring means secured within the frontal sinus cavity. A drug-containing fluid is released directly into the frontal sinus drainage system.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: November 24, 2020
    Assignee: Entellus Medical, Inc.
    Inventors: Peter T. Keith, Reuben C. Setliff, III
  • Patent number: 10835643
    Abstract: A drug coating layer on a non-porous nylon elastomer balloon substrate surface comprising a plurality of elongated bodies with long axes wherein each elongated body is formed of a crystal of a water-insoluble drug and is independently formed on the substrate surface, wherein the long axes of the elongated bodies are substantially linear in shape, and the long axes of the elongated bodies form an angle in a predetermined range with respect to a substrate plane with which the long axis of the elongated body intersects. The drug coating layer can provide low toxicity and a high intravascular stenosis inhibitory effect.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: November 17, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Keiko Yamashita, Hiroshi Goto, Shigenori Nozawa, Katsumi Morimoto
  • Patent number: 10835721
    Abstract: A delivery system includes a catheter, and a drug coated angioplasty balloon mounted on the catheter. The balloon has a wrapped or folded delivery configuration and an expanded deployed configuration. A protective sleeve surrounds the drug coated balloon in the delivery configuration to minimise wash-off of drug from the balloon during delivery. The protective sleeve is retractable, so that once the drug coated balloon is at or near the treatment site, the sleeve can be retracted to allow the drug coated balloon to operate effectively. The protective sleeve can have a spacer mounted to or integral with the protective sleeve. The spacer in one case can comprise of interior ribs or ridges on the sleeve which minimise the surface area of the sleeve in direct contact with the drug coating on the balloon.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: November 17, 2020
    Assignee: Merit Medical Ireland Limited
    Inventors: David Slattery, Jonathan Akehurst, David Kelly, John Joseph Kelly
  • Patent number: 10835719
    Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent, an antioxidant, and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In some embodiments, the additive is a liquid. In other embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide or ester groups.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: November 17, 2020
    Assignee: Lutonix, Inc.
    Inventor: Lixiao Wang
  • Patent number: 10828460
    Abstract: Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: November 10, 2020
    Assignee: Silk Road Medical, Inc.
    Inventor: David W. Chang
  • Patent number: 10828470
    Abstract: Devices, systems, and methods are disclosed that help deliver catheters or other medical devices to locations within a patient's body. The device includes a transporter catheter having a proximal end and a distal end, at least a first balloon located at the distal end, substantially at a tip of the transporter catheter, and at least a second balloon located between the distal end and the proximal end of the transporter catheter. The first balloon is an orienting balloon and the second balloon is an anchor balloon. The transporter catheter may include a single lumen or more than one lumen. The transporter catheter may include a shaft comprising an inner layer and an outer layer, the inner layer may be made of a material more flexible than the material of the outer layer. The outer layer may also include a braided-wire assembly, said braided-wire assembly being formed by braiding a plurality of flat wires or circular wires. The braided-wire assembly may wrap around the inner layer.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: November 10, 2020
    Assignee: VASOINNOVATIONS INC.
    Inventors: Rajendra Gurudas Sardesai, Samir Bipin Pancholy, Tejas Madhusudan Patel
  • Patent number: 10779855
    Abstract: An arterial access device has an internal lumen and a proximal port, the arterial access device sized and shaped to be inserted directly into an arterial access site in the common carotid artery such that the lumen provides a passageway for an interventional device to be inserted via the proximal port into the carotid artery. The arterial access device has a distal portion that is configured to be inserted into an arterial pathway through the access site, and a proximal portion configured to extend outward from the access site when the distal portion is in the arterial pathway.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: September 22, 2020
    Assignee: Route 92 Medical, Inc.
    Inventor: Michi E. Garrison
  • Patent number: 10773058
    Abstract: Devices, systems, and methods are disclosed that help deliver catheters or other medical devices to locations within a patient's body. The device comprises a transporter catheter having a proximal end and a distal end, at least a first balloon located at the distal end, substantially at a tip of the transporter catheter, and at least a second balloon located between the distal end and the proximal end of the transporter catheter. The first balloon is an orienting balloon and the second balloon is an anchor balloon. The transporter catheter may include a single lumen or more than one lumen. The transporter catheter may include a shaft comprising an inner layer and an outer layer, the inner layer may be made of a material more flexible than the material of the outer layer. The outer layer may also comprise a braided-wire assembly, said braided-wire assembly being formed by braiding a plurality of flat wires or circular wires. The braided-wire assembly may wrap around the inner layer.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: September 15, 2020
    Assignee: VASOINNOVATIONS INC.
    Inventors: Rajendra Gurudas Sardesai, Samir Bipin Pancholy, Tejas Madhusudan Patel
  • Patent number: 10773059
    Abstract: Devices, systems, and methods are disclosed that help deliver catheters or other medical devices to locations within a patient's body. The device comprises a transporter catheter having a proximal end and a distal end, at least a first balloon located at the distal end, substantially at a tip of the transporter catheter, and at least a second balloon located between the distal end and the proximal end of the transporter catheter. The first balloon is an orienting balloon and the second balloon is an anchor balloon. The transporter catheter may include a single lumen or more than one lumen. The transporter catheter may include a shaft comprising an inner layer and an outer layer, the inner layer may be made of a material more flexible than the material of the outer layer. The outer layer may also comprise a braided-wire assembly, said braided-wire assembly being formed by braiding a plurality of flat wires or circular wires. The braided-wire assembly may wrap around the inner layer.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: September 15, 2020
    Assignee: VASOINNOVATIONS, INC.
    Inventors: Rajendra Gurudas Sardesai, Samir Bipin Pancholy, Tejas Madhusudan Patel
  • Patent number: 10751517
    Abstract: Devices, systems, and methods are disclosed that help deliver catheters or other medical devices to locations within a patient's body. The device comprises a transporter catheter having a proximal end and a distal end, at least a first balloon located at the distal end, substantially at a tip of the transporter catheter, and at least a second balloon located between the distal end and the proximal end of the transporter catheter. The first balloon is an orienting balloon and the second balloon is an anchor balloon. The transporter catheter may include a single lumen or more than one lumen. The transporter catheter may include a shaft comprising an inner layer and an outer layer, the inner layer may be made of a material more flexible than the material of the outer layer. The outer layer may also comprise a braided-wire assembly, said braided-wire assembly being formed by braiding a plurality of flat wires or circular wires. The braided-wire assembly may wrap around the inner layer.
    Type: Grant
    Filed: April 25, 2020
    Date of Patent: August 25, 2020
    Assignee: VASOINNOVATIONS INC.
    Inventors: Rajendra Gurudas Sardesai, Samir Bipin Pancholy, Tejas Madhusudan Patel
  • Patent number: 10751215
    Abstract: A method may include accessing a terminal branch of an ophthalmic artery through a face of a subject. Additionally, the method may include positioning a device within the ophthalmic artery of the subject and treating at least one of a blockage, a stenosis, a lesion, plaque or other physiology in at least one of the ophthalmic artery or a junction between an internal carotid artery and the ophthalmic artery.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: August 25, 2020
    Assignee: J.D. Franco & Co., LLC
    Inventors: Michael Calhoun, Jeff Franco, Robert M. Vidlund
  • Patent number: 10737004
    Abstract: A medical prosthesis includes a tube having a length between a first end and a second end. The tube includes a polymer and at least one drug. The tube is configured to be manipulated to selectively increase and decrease the length of the tube. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: August 11, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie Soskin, Jonathan Sturtevant
  • Patent number: 10722243
    Abstract: There are disclosed various dispensing mechanisms for dispensing filamentary material through a catheter into a treatment site of a patient, for example into an aneurysm sack in a patient's vessel. In one embodiment, the dispensing assembly includes a chamber having a spherical carrier onto which filamentary material is wound. Upon injecting driving fluid into the dispensing assembly filamentary material unwinds from the spherical carrier and is pulled through the catheter to be dispensed from the distal end of the catheter. The apparatus includes a pressure sensitive valve disposed at the inlet or the outlet of the receptacle, the pressure sensitive valve being closed when the pressure of driving fluid is below a threshold and open when the pressure of driving fluid is above the threshold. The pressure sensitive valve, when open, allows fluid flow through the chamber and dispensation of filamentary material from the outlet.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: July 28, 2020
    Assignee: Cook Medical Technologies LLC
    Inventors: Aidan Furey, Steen Aggerholm, Palle Munk Hansen, Anders Ginge Jensen, Kirsten Asser Larsen