Solid Ejected From Body Inserted Conduit Patents (Class 604/60)
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Patent number: 8308758Abstract: The invention provides a closure device (1) for sealing an incision channel leading through a vessel wall and into the vessel. The closure device (1) comprises a haemostatic material (3), which is contained in the distal end of an elongated insertion assembly (2). The insertion assembly (2), which comprises a stationary part (4) and a retractable part (5) being slidably movable with regard to each other, is adapted to be attached to an introducer (7) being in position in the incision channel, so that the insertion assembly (2) can be slid along the introducer (7) until the distal end of the insertion assembly (2) is in contact with the vessel wall, where the haemostatic material (3) is delivered in the incision channel by a retracting movement of the retractable part (5).Type: GrantFiled: November 29, 2004Date of Patent: November 13, 2012Assignee: Radi Medical Systems ABInventor: Dan â„«kerfeldt
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Publication number: 20120232473Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.Type: ApplicationFiled: March 9, 2012Publication date: September 13, 2012Applicant: ACELRX PHARMACEUTICALS, INC.Inventors: Andrew Poutiatine, Bruce Edwards, Charles Rampersaud
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Patent number: 8251946Abstract: A method for constructing an instrument with a two-part plunger for subcutaneous implantation is provided. An incising body is formed by defining a non-circular coaxial bore and sharpening a distal bottom edge. A two-part plunger including a tongue blade assembly and a plunger assembly is constructed. The tongue blade assembly is constructed by sharpening a beveled end of a flat thin tongue blade and by affixing a straight tongue blade shaft to an end of the tongue blade opposite the beveled end. The tongue blade assembly has a length exceeding the coaxial bore. The plunger assembly is constructed by affixing a plunger to a plunger shaft on a distal end. The plunger assembly has a length exceeding the coaxial bore and is oriented adjacent to the tongue blade assembly. The two-part plunger is inserted through an end of the incising body.Type: GrantFiled: July 14, 2010Date of Patent: August 28, 2012Assignee: Cardiac Science, Inc.Inventor: Gust H. Bardy
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Patent number: 8246572Abstract: Disclosed herein is a bone graft applicator assembly including a specially designed applicator, attached to a reservoir of bone graft material, such that the graft material can be moved into the delivery portion while the tip of the delivery portion is in place. The instantly disclosed device allows for the collapse of the delivery tip so that the tip can be placed between vertebras or alternatively within any bony structure or implant where the placement of bone graft material would be desirable, and then expanded to allow the bone graft material to be placed between the vertebras or the like while maintaining the geometry of the space into which the bone graft material is being placed.Type: GrantFiled: December 16, 2010Date of Patent: August 21, 2012Assignee: Lary Research & Development, LLCInventors: Jeffrey B. Cantor, Banning G. Lary, Todd P. Lary
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Patent number: 8246571Abstract: Drug depot storage and delivery devices and methods for delivering a drug depot to a site beneath the skin of a patient are provided. In various embodiments, the drug depot storage and delivery device comprises a retaining member that in an open position allows delivery of the drug depot from the drug cartridge to the target tissue site. In various embodiments, the drug depot storage and delivery device comprises a retaining member that in a closed position reduces or prevents delivery of the drug depot from the drug cartridge to the target tissue site.Type: GrantFiled: August 24, 2010Date of Patent: August 21, 2012Assignee: Warsaw Orthopedic, Inc.Inventors: Thomas Andrew Simonton, William F. McKay
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Publication number: 20120203200Abstract: A device for substance delivery to and/or extraction from the tympanic cavity, comprising: a housing, having a distal surface, a proximal surface that is opposite to the distal surface, and a circumscribed surface that connects the distal surface and the proximal surface; at least one piercing element having at least one proximal piercing end and at least one distal piercing end, disposed within the housing in such manner that the at least one distal piercing end is/are generally facing the distal surface of the housing; and a means for flexing the tympanic membrane toward the distal end of the at least one piercing element.Type: ApplicationFiled: October 13, 2010Publication date: August 9, 2012Applicant: ENTRATYMPANIC, LLCInventors: George B. Kenney, Christian Pfeffer, Lev Rosenblum
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Patent number: 8235937Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.Type: GrantFiled: February 7, 2011Date of Patent: August 7, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, Wendy Naimark, Toby Freyman, Samuel Epstein
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Publication number: 20120172836Abstract: Treatments and devices for generating and using interleukin-1 receptor antagonist (IL-1ra). An implantable device is loaded with adipose tissue and/or white blood cells and inserted into an inflammation site in a patient to produce interleukin-1 receptor antagonist in vivo. The implantable device has an enclosed or substantially enclosed body that defines an internal space. At least a portion of the body comprises a first bioresorbable material and a second bioresorbable material is within the internal space along with one or more voids. The second bioresorbable material includes an activation surface to activate adipose tissue and/or white blood cells loaded into the device to produce IL-1ra.Type: ApplicationFiled: August 27, 2010Publication date: July 5, 2012Applicant: Biomet, Biologics, LLC.Inventors: Joel C. Higgins, James M. McKale, Jennifer E. Woodell-May
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Patent number: 8192393Abstract: Rectal suppositories are used to administer a predetermined drug dosage to treat a variety of diseases and symptoms in a variety of patient populations. Certain medical conditions, such as digestive disorders, may be more effectively treated when the suppository is placed in a particular location of the patient's anal canal or rectum. A method and apparatus for inserting a suppository into an animal or human may include an applicator having a barrel and plunger. The barrel maintains a first gas flow path during insertion of a suppository and the plunger maintains a second gas flow path during withdrawal of the plunger. By maintaining a first and second gas flow path, trapped air and suction effects on the suppository are minimized or eliminated. Furthermore, patients may immediately resume day-to-day activities. These benefits may encourage patients to maintain a course of treatment thereby potentially avoiding additional complications, hospitalization, and costs.Type: GrantFiled: October 7, 2008Date of Patent: June 5, 2012Assignee: Christcot Medical CompanyInventor: Jennifer Davagian Ensign
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Patent number: 8177738Abstract: Apparatus and methods for delivering a clotted biological component (such as blood, autologous conditioned plasma (ACP), platelet-rich plasma (PRP), bone marrow aspirate (BMA), demineralized bone matrix, anticoagulants and/or clotting agents, or combination of these materials) into a tissue void (for example, a bone void such as a bone tunnel, socket, opening or cavity), and then cutting the clotted biological component with a cutting or shearing mechanism at the tissue surface. The apparatus is provided with a tube and a cutting or shearing mechanism (provided on or within the distal end of the tube) that is actuated to cut or break off the clot at the desired insertion length. The tube may then be placed over the next tissue void so that the obturator drives the next clot into the next tissue void until all tissue voids are filled. Upon insertion at the defect site, the biological component advances the healing of the damaged tissue and tissue growth.Type: GrantFiled: July 21, 2010Date of Patent: May 15, 2012Assignee: Arthrex, Inc.Inventors: Reinhold Schmieding, Robert Benedict
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Publication number: 20120116297Abstract: A pill delivery device is provided for inserting pills into enclosed regions within human body cavities, comprising an arcuate, rigid applicator tube, a plunger and a flexible pill-retaining sleeve. The pill-retaining sleeve is secured to a lower end of the applicator tube and has an aperture disposed at a lower end of the sleeve. The aperture prevents pills from falling from the sleeve; however the sleeve is flexible to permit distortion of the aperture, thereby allowing pills to be pushed therethrough. The plunger has a handle disposed at a top end and a working end in the shape of a ball, disposed at its lower end. In use, a pill is inserted into the top end of the tube. The device is then inserted into a body cavity and the plunger is utilized to force medication through the retaining sleeve and into the body cavity.Type: ApplicationFiled: November 4, 2011Publication date: May 10, 2012Inventor: Cynthia Sheffield
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Publication number: 20120109046Abstract: The invention relates to a medicament delivery device (1, 100) for delivering one or more solid dose pegs (10, 110) through the skin. The device (1, 100) has a number of exit openings (9, 109) corresponding to the number of solid dose pegs (10, 110) to be delivered. A detachable portion (3, 103) of the device (1, 100) is removed before use to uncover the exit openings (9, 109) and a release rod (17, 117). When the exit openings (9, 109) are pressed against the skin the release rod (17, 117) automatically disables a safety mechanism adapted to prevent unintended activation of the device (1, 100).Type: ApplicationFiled: March 26, 2010Publication date: May 3, 2012Applicant: Novo Nordisk A/SInventors: Henrik Ljunggreen, Torben Strom Hansen
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Publication number: 20120101429Abstract: The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.Type: ApplicationFiled: December 30, 2011Publication date: April 26, 2012Inventors: Donald J. EATON, Mary Lynn Moran, Rodney A. Brenneman
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Patent number: 8152755Abstract: A catheter for delivering a therapeutic agent to a target site of a human or animal subject can include a substantially flexible and biocompatible catheter body having a proximal end and a distal end. An eductor can be located at the distal end of the catheter body, and a first lumen within the catheter body for housing the therapeutic agent can be in fluid communication with the eductor. A second lumen, also in fluid communication with the first lumen, can extend from the proximal end of the catheter body towards the eductor and can have an output port at the distal end of the catheter body. The eductor can be operable to induce the therapeutic agent to flow from the first lumen out of the output port in response to fluid flowing through the second lumen.Type: GrantFiled: March 24, 2010Date of Patent: April 10, 2012Assignee: Cell Precision LLCInventors: Michael L. Wach, W. Robert Taylor, Jack C. Griffis, III, Raymond P. Vito
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Patent number: 8142390Abstract: A syringe device (1) with an elongate plunger space (2), a receiving chamber (3) for receiving solid medicaments (4), and a hollow needle (5) arranged in the plunger space (2), and also a plunger (7) which is suitable for movement in the plunger space (2) and bears a ram (8) for pushing out the solid medicament (4). For displacement of the plunger (7) there is a plunger rod (9) which acts thereon and, for its use, can be extended telescopically out of the plunger space (2) and relative to the plunger (7) and can be coupled to the plunger by means of a lock (10). The locking of the plunger (7) to the plunger space (2) is opened or released only by complete withdrawal of the plunger rod (9) in its operative position while at the same time the plunger rod (9) is coupled to the plunger (7) in this position in the pushing direction such that the medicament can then be pushed out.Type: GrantFiled: December 3, 2007Date of Patent: March 27, 2012Assignee: Rexam Pharma GmbHInventors: Uwe Birmelin, Martin Eberl-Lang
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Publication number: 20120065613Abstract: A bone graft system for providing bone graft material to a site of interest includes a multiple unit bone graft material loading device and a conduit. The multiple unit bone graft material loading device is configured to accept a plurality of pre-formed bone graft material units and includes a plurality chambers configured to accept a pre-formed bone graft unit. The conduit includes a first opening and second opening. The first opening is operably connected with the multiple unit bone graft material loading device to accept bone graft material from the multiple unit bone graft material loading device. The second opening is configured to deliver bone graft material to a site of interest.Type: ApplicationFiled: July 14, 2011Publication date: March 15, 2012Inventors: John R. Pepper, Daniel K. Farley, Christopher T. Martin, Stephanie Zalucha, Miguelangelo J. Perez-Cruet
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Publication number: 20120053561Abstract: Drug depot storage and delivery devices and methods for delivering a drug depot to a site beneath the skin of a patient are provided. In various embodiments, the drug depot storage and delivery device comprises a retaining member that in an open position allows delivery of the drug depot from the drug cartridge to the target tissue site. In various embodiments, the drug depot storage and delivery device comprises a retaining member that in a closed position reduces or prevents delivery of the drug depot from the drug cartridge to the target tissue site.Type: ApplicationFiled: August 24, 2010Publication date: March 1, 2012Applicant: WARSAW ORTHOPEDIC, INC.Inventors: Thomas Andrew Simonton, William F. McKay
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Publication number: 20120016338Abstract: Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage form is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i.e., about 0.9%) upon absorption by the body of the subject being treated.Type: ApplicationFiled: September 23, 2011Publication date: January 19, 2012Applicant: BOSTON SCIENTIC SCIMED, INC.Inventor: Joseph V. DiTrolio
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Patent number: 8084053Abstract: Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.Type: GrantFiled: August 7, 2009Date of Patent: December 27, 2011Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, James M. Flink, Jens Ulrich Poulsen, Søren Aasmul, Philip Hansen, Claus Juul Mortensen
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Publication number: 20110313348Abstract: The invention relates to a novel drug delivery technology. More particularly the invention relates to a method of delivering at least one therapeutic compound or a formulation comprising the at least one therapeutic compound to a patient; to a throwaway or reusable device for delivering at least one therapeutic compound or a formulation comprising the at least one therapeutic compound to a patient in a manner as set out by the method; to a pioneer projectile for use in said method; to formulations for use in said method and to an injectate comprising a pioneer projectile and formulation. It also relates to a disposable component containing either a pioneer projectile or an injectate. The invention also relates to a throwaway or reusable device for delivering at least one therapeutic compound, or a formulation comprising the at least one therapeutic compound (hereafter drug) to a patient, and a method for administering a drug to a patient using said device.Type: ApplicationFiled: August 25, 2011Publication date: December 22, 2011Applicant: GLIDE PHARMACEUTICAL TECHNOLOGIES LIMITED,Inventors: David Stuart POTTER, Charles David Ogilvy Potter
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Patent number: 8034016Abstract: A flow regulating implant is provided with one or more grooves for allowing fluid flow. One or more grooves may have a constant or varying cross-section along its length. One or more grooves may have in it biodegradable material, absorbable material, and/or threads or sutures. A resilient band or coating may be placed around the implant or one or more grooves, to act as a pressure regulator. The implant may have a side projection, such as a side pin, for engaging tissue. The implant may comprise two or more parts that are held at a distance from each other to allow fluid flow between the parts.Type: GrantFiled: December 7, 2007Date of Patent: October 11, 2011Assignee: Optonol, Ltd.Inventors: Ira Yaron, Elie Dahan
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Patent number: 8029458Abstract: The invention relates to a device which is used to inject an implant (6) into tissues (50). The inventive device is characterized in that it comprises: a main hollow body (2; 2?) having a hollow needle (4; 4?) fixed thereto, into which the implant (6) is introduced; a secondary body (26; 26?) which is disposed coaxially inside the main body (2; 2?) and which surrounds the needle (4; 4?); and a plunger rod (36; 36?) which can slide coaxially inside the hollow needle (4; 4?).Type: GrantFiled: November 15, 2005Date of Patent: October 4, 2011Assignee: Sociétéde Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.) SASInventors: Roland Cherif-Cheikh, Christophe Aubert, Thierry Rimlinger, Fabrice Bonacci, Serge Barneaud
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Patent number: 8007500Abstract: An extractable device is used to insert a medicinal filling into an animal tissue. The device comprises a filling member and a pasty medicine. The filling member is made of a flexible and permeable wall and is provided with a holding portion and an injection port via which the pasty medicine is injected into the holding portion after the filling member is inserted into the animal tissue. The holding portion is provided with an opening which is releasably lashed by one end of one or more threads so as to make the opening leakproof. Upon completion of solidification of the pasty medicine in the holding portion of the filling member, other end of the thread is pulled to unlash the opening of the holding portion, thereby enabling the filling member to be extracted from the animal tissue so as to leave only the medicine in the animal tissue.Type: GrantFiled: February 12, 2007Date of Patent: August 30, 2011Assignee: Crosstrees Medical, Inc.Inventors: Kwan Ku Lin, Philip S. Yuan
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Patent number: 7998108Abstract: Disclosed herein is an injector device including an inserter element, a head element, an implant and a set of detachable protector elements for secured device handling. The device comprises a stop that controls the penetration depth of the device during injection. The device may comprise a removable catch that prevents the implant from exiting the device due to the advancement of its inserter element. The device may comprise a disengageable block that prevents the implant from exiting the device from its head element. The device may be configured for intraocular drug delivery.Type: GrantFiled: September 12, 2007Date of Patent: August 16, 2011Assignee: pSivida US, Inc.Inventors: Martin Nazzaro, Hong Guo, Ron LeBlanc, Josh York
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Patent number: 7993345Abstract: An extractable device is used to insert a medicinal filling into a spinal disc. The device comprises a filling member and a flowable medicine. The filling member is made of a flexible and permeable wall and is provided with a holding portion and an injection port via which the flowable medicine is injected into the holding portion after the filling member is inserted into the spinal disc. The holding portion is provided with an opening which is releasably lashed by one end of one or more threads so as to make the opening leakproof. Upon completion of solidification of the flowable medicine in the holding portion of the filling member, other end of the thread is pulled to unlash the opening of the holding portion, thereby enabling the filling member to be extracted from the spinal disc so as to leave only the medicine in the spinal disc.Type: GrantFiled: July 2, 2010Date of Patent: August 9, 2011Assignee: Crosstress Medical, Inc.Inventors: Philip S. Yuan, Kwan Ku Lin, Robert M. Scribner
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Patent number: 7993343Abstract: An extractable device is used to insert a medicinal filling into a vertebral body. The device comprises a filling member and a pasty medicine. The filling member is made of a flexible and permeable wall and is provided with a holding portion and an injection port via which the pasty medicine is injected into the holding portion after the filling member is inserted into the vertebral body. The holding portion is provided with an opening which is releasably lashed by one end of one or more threads so as to make the opening leakproof. Upon completion of solidification of the pasty medicine in the holding portion of the filling member, other end of the thread is pulled to unlash the opening of the holding portion, thereby enabling the filling member to be extracted from the vertebral body so as to leave only the medicine in the vertebral body.Type: GrantFiled: February 12, 2007Date of Patent: August 9, 2011Assignee: Crosstrees Medical, Inc.Inventors: Kwan Ku Lin, Philip S. Yuan
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Patent number: 7985197Abstract: A therapeutic-substance carrying/administering appliance includes a cylindrical outer sheath; a slide member installed in the cylindrical outer sheath to be slidable therein; and a sheet supporting member, connected to a distal end of the slide member and made of a resilient material, for supporting a sheet-shaped therapeutic substance. The sheet supporting member is held in a flat unrolled shape in a free state in which the sheet supporting member projects outwardly from a distal end of the cylindrical outer sheath. When the sheet supporting member is in the free state, sliding the slide member in a retracting direction causes the sheet supporting member to contact the distal end of the cylindrical outer sheath, and subsequently further moving the slide member in the retracting direction causes the sheet supporting member to be retracted into the cylindrical outer sheath while being deformed into a tubular shape.Type: GrantFiled: May 19, 2008Date of Patent: July 26, 2011Assignees: Hoya Corporation, Tokyo Women's Medical UniversityInventors: Masanori Maeda, Hidenori Takushima, Teruo Okano, Masayuki Yamato, Hiroshi Iseki, Ryoichi Nakamura, Takamasa Onuki, Masato Kanzaki, Takashi Suzuki, Shigeru Nagai
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Publication number: 20110166509Abstract: Apparatus for use with tissue (22) of a subject, including a substance (24) configured to be injected into the tissue, and first and second tissue-squeezing surfaces (20) configured to be placed on first and second sides of the tissue, to exert pressure on the tissue by being moved toward each other in response to a squeezing force (F), and to facilitate injection of the substance into the tissue by releasing the substance in response to application of the squeezing force.Type: ApplicationFiled: September 14, 2009Publication date: July 7, 2011Applicant: LAMODEL LTD.Inventors: Yossi Gross, Oz Cabiri
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Publication number: 20110152755Abstract: A device (1; 1001) for injecting solid matter (500; 1500) into a human or animal body (600; 1600) comprises a housing (100; 1100), a syringe body (200; 1200) for holding the solid matter (500; 1500), connected to a cannula (220; 1220), a primary plunger (230; 1230), which can be displaced in the syringe body (200; 1200) and in the cannula (220; 1220), and a secondary plunger (300; 1300), which can be displaced in the housing (100; 1100). The device (1; 1001) comprises a force-transmission mechanism, which can act between the secondary plunger (300; 1300) and the syringe body (200; 1200) and/or the cannula (220; 1220), wherein an actuation of the secondary plunger (300; 1300) in the distal direction can bring about a displacement of the syringe body (200; 1200) and/or the cannula (220; 1220) in the proximal direction.Type: ApplicationFiled: December 20, 2010Publication date: June 23, 2011Applicant: FORTEQ NIDAU AGInventor: Christian SCHMALZ
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Publication number: 20110144622Abstract: Methods, systems, and kits for subcutaneously implanting articles, such as drug inserts and reservoirs. The methods rely on percutaneously forming a tissue tract and radially dilating the tract to a diameter which permits introduction of the article. By fully expanding the lumenal diameter of the tissue tract prior to introduction of the article, damage to the article resulting from passage through a partially expanded tissue tract can be avoided. In the exemplary embodiment, a radially expandable sleeve is first percutaneously introduced to the subcutaneous target site. An assembly of a cannula and dilator is then passed through the sleeve, effecting radial expansion. The dilator is removed and the article is then introduced through a lumen of the cannula.Type: ApplicationFiled: February 22, 2011Publication date: June 16, 2011Inventors: Michael J. Orth, Mark C. Yang
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Publication number: 20110130715Abstract: The present invention provides a catheter and catheter assembly for delivering micronized therapeutic agents to a target site in the body and, in particular, to a target site in the heart. The micronized therapeutic agents are delivered in aerosol form or dry powder form. The present invention also provides a method of delivering micronized therapeutic agents to a target site in the body by placing the therapeutic agents in a catheter, positioning the catheter in the target site, and exposing the therapeutic agents to an energizing mechanism sufficient to create supersonic flow to carry the therapeutic agents from a stationary state in the catheter to a mobile state towards the target site.Type: ApplicationFiled: February 7, 2011Publication date: June 2, 2011Applicant: BOSTON SCIENTIFIC SCIMEDInventors: Maria Palasis, Wendy Naimark, Toby Freyman, Samuel Epstein
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Patent number: 7942843Abstract: System and methods disclosed provide a device for inserting an implant with a medical function into body tissue. The device can include a channel passing through the implant, a cannulus with a channel sized to hold the implant, and a pusher with a channel and sized to be situated inside the channel of the cannulus behind the implant, and adapted to push the implant through a distal end of the cannulus into the tissue. The device can also include a restraining element that extends through the channel of the pusher and at least partly through the channel of the implant when they are so situated in the channel of the cannulus, which restrains the implant, but allows the implant to exit the distal end of the cannulus when the implant is pushed with a force small enough so as not to damage the function of the implant in the tissue.Type: GrantFiled: July 16, 2009Date of Patent: May 17, 2011Assignee: Navotek Medical Ltd.Inventors: Michal Tune, David Maier Neustadter, Giora Kornblau, Tal Shchory
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Patent number: 7935089Abstract: A silicon breast implant injector for augmentation mammaplasty which includes a hollow tube and a plunger. The hollow tube has a barrel which has one end tapered to form a first arched barrel connecting to an inverse second arched barrel which in turn is connected to an ejection opening formed at the same diameter as the second arched barrel but into a short inflexible length tube. The plunger can push a silicon breast implant s held in the hollow tube through an incision into patient's submammary pocket. Coupled with a smooth connection between the first arched barrel and the second arched barrel, push resistance can be reduced, and thus can smoothly, quickly, easily and safely move the silicon breast implant into the submammary pocket.Type: GrantFiled: January 8, 2008Date of Patent: May 3, 2011Inventor: Su-Ben Tsao
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Publication number: 20110098675Abstract: A device (100) for injecting a solid (500) into a human or animal body comprises a syringe body (300) with a first tubular interior for receiving the solid (500), a retaining device for retaining the solid (500) in the syringe body (300), and a needle (200) with a second tubular interior. The needle (200) is connected to the syringe body (300) such that the second tubular interior of the needle (200) communicates with the first tubular interior of the syringe body (300). The device further comprises a ram (400), which can be driven through the first interior into the second interior. The ram (400) can cooperate directly with the retaining device, such that the retaining device can be deactivated by means of the ram (400).Type: ApplicationFiled: October 22, 2010Publication date: April 28, 2011Applicant: FORTEQ NIDAU AGInventor: Christian SCHMALZ
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Patent number: 7914481Abstract: An epidural needle for placement of a pain management electrode includes an elongated bevel having a heel segment defined by a proximal rounded inner edge in which the heel has an electropolished radius of at least about 0.002 inch extending substantially continuously along the inner edge that defines the heel; a method for fabricating the needle.Type: GrantFiled: August 30, 2007Date of Patent: March 29, 2011Assignee: Spectra Medical Devices, Inc.Inventors: Anthony C. Arrigo, Raymond T. Charbonneau
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Publication number: 20110060310Abstract: The delivery of biopharmaceutical and other therapeutic agents parenterally to an animal via a minimally invasive, low pain administration is provided. The agents are delivered to the patient via, e.g., the epidermal, dermal, or subcutaneous layer of the skin in a concentrated fours of injectable paste of slurry.Type: ApplicationFiled: November 16, 2010Publication date: March 10, 2011Inventors: Steven Prestrelski, Kevin Brodbeck
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Publication number: 20110040245Abstract: The present disclosure refers to hand operated disposable devices for the administration of drugs, vaccines and other medicaments in the form of solid injectable needles. The devices incorporate mechanisms for the automatic retraction of the injection rod even when the user continues to exert pressure on the device. The devices can incorporate an injectable needle in a sheath or cartridge that facilitates its manufacture and manipulation. These injection devices can only be used once and their use results in a change of configuration that renders them non operational and prevents contact with parts that have been exposed to the patient's tissues.Type: ApplicationFiled: February 18, 2009Publication date: February 17, 2011Inventor: Arcadio Garcia De Castro Andrews
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Publication number: 20110040279Abstract: A method for delivering particles to a target location of a subject includes slidably disposing a polymeric carrier in a lumen of a catheter. The lumen extends in the catheter from a proximal opening to a delivery region. The method further includes inserting the delivery region of the catheter in the target location of the subject and forcing the particles through the lumen of the catheter to cause the carrier and the particles to exit the delivery region of the catheter. The particles may be cells or drug-loaded microspheres. The carrier can serve to retain the particles in the target location for a period of time. For treatment of vertebral disc degeneration, the particles can be stem cells, the carrier can be formed from collagen, and the target location can be the nucleus pulposus.Type: ApplicationFiled: August 12, 2009Publication date: February 17, 2011Applicant: Medtronic, Inc.Inventor: Andrew James Lowenthal Walsh
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Publication number: 20100318022Abstract: A straight cutting tip for a straight bore subcutaneous implantation instrument is provided. An incising shaft body defines an axial bore extending continuously throughout the incising shaft body's length. The axial bore is open on both distal and proximal ends of the incising shaft body and has a non-circular cross section of at least five millimeters. A beveled surface is transversely formed beginning on a top surface and ending on a bottom surface of the distal end of the incising shaft body. A straight and sharpened cutting edge with rounded ends on each side curves inwardly towards the proximal end of the incising shaft body. The cutting edge is defined only along a bottom distal edge of the beveled surface. An attachment point is formed on the proximal end of the incising shaft body.Type: ApplicationFiled: August 23, 2010Publication date: December 16, 2010Inventor: Gust H. Bardy
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Publication number: 20100298807Abstract: The invention pertains to an applicator (1) for inserting an implant, in particular a rod-like implant (2) containing an active substance, under the skin of a human or animal, comprising a housing (3), a cannula (6), a cannula holder (9), an implant (2) accommodated inside the cannula (6) and/or the cannula holder (9), a protective cover (7) for the cannula (6), and a mechanism (22, 23, 7) which, at least after the cover (7) has been removed from the cannula (6), secures the implant (2) inside the cannula (6) and/or cannula holder (9) . The mechanism (22, 23, 7) disengages the implant (2) during insertion of the cannula (6) or after the cannula (6) has been inserted. Substantially no lateral force will be exerted during the expelling of the implant from the cannula.Type: ApplicationFiled: January 20, 2006Publication date: November 25, 2010Applicant: AKZO NOBEL N.V.Inventors: Willem Jansen, Maurice Petrus Wilhelmus Tak, Hendricus Johannes Vertegaal, Iris Epkjen Hobo Van Der Graaf
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Publication number: 20100292671Abstract: The disclosed invention provides apparatus and methods for delivering a payload to a target location inside the body. A finger board is retained on the finger of a user, having a proximal end and a distal end. A payload holder is included at the distal end of the finger board for holding a payload during positioning and prior to delivery. An ejector is included for the purpose of ejecting the payload from the payload holder when actuated by a user.Type: ApplicationFiled: May 18, 2010Publication date: November 18, 2010Applicants: TRIUNE IP LLC, TAP PRODUCTS LLCInventors: Fred A. Allgood, Ross Teggatz, Wayne T. Chen, Nick Papacharalambous
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Publication number: 20100286598Abstract: The application refers to hypodermic needles (101) for the parenteral administration of liquids. The needles incorporate at their sharp-end an obstruction (102) of rapidly water-soluble material that dissolves within living tissues once the needle is injected. These needles ensure that the end user can only operate the syringe, or injection device, once the needle has been injected. The use of these hypodermic needles avoids the possibility of the user expelling any amount of liquid prior injection, ensuring the administration of the complete dose. These hypodermic needles are of special interest in preloaded injection devices and in the administration of small volumes of liquid were ejection of part of the dose by the user may result in the administration of only a fraction of the intended dose.Type: ApplicationFiled: October 8, 2008Publication date: November 11, 2010Inventor: Arcadio Garcia De Castro Andrews
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Patent number: 7811245Abstract: An object-delivery shuttle for delivering an object over an elongate medical device, such as a wire guide, to a desired location within a body.Type: GrantFiled: April 21, 2006Date of Patent: October 12, 2010Assignee: Wilson-Cook Medical Inc.Inventor: Kenneth C. Kennedy, II
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Publication number: 20100256555Abstract: A syringe device (1) has an elongate plunger space (2), a receiving chamber (3) for receiving solid medicaments (4), and a hollow needle (5) arranged in the plunger space (2), and also a plunger (7) which is suitable for movement in the plunger space (2) and bears a ram (8) for pushing out the solid medicament (4). For displacement of the plunger (7) there is a plunger rod (9) which acts thereon and, for its use, can be extended telescopically out of the plunger space (2) and relative to the plunger (7) and can be coupled to the plunger by means of a lock (10). The locking of the plunger (7) to the plunger space (2) is opened or released only by complete withdrawal of the plunger rod (9) in its operative position while at the same time the plunger rod (9) is coupled to the plunger (7) in this position in the pushing direction such that the medicament can then be pushed out.Type: ApplicationFiled: December 3, 2007Publication date: October 7, 2010Applicant: REXAM PHARMA GMBHInventors: Uwe Birmelin, Martin Eberl-Lang
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Publication number: 20100249696Abstract: A straight cutting tip for a full large bore subcutaneous implantation instrument is provided. An incising shaft body defines an axial bore extending continuously throughout the incising shaft body's length. The axial bore is open on both distal and proximal ends of the incising shaft body and has a non-circular cross section of at least five millimeters. A beveled surface is transversely formed beginning on a top surface and ending on a bottom surface of the incising shaft body. A cutting tip with a pair of longitudinal straight cutting edges is formed on each side and is progressively defined outwardly from the cutting tip to the sides of the beveled surface at the bottom surface of the incising shaft body. An attachment point is formed on the proximal end of the incising shaft body.Type: ApplicationFiled: June 14, 2010Publication date: September 30, 2010Inventor: Gust H. Bardy
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Patent number: 7785298Abstract: Systems and methods of co-injecting a solid object and an amount of fluid into a patient's tissue includes separably coupled syringe and needle portions. The syringe portion includes a barrel, a plunger, and a pushrod for disposing the solid object that is capable of independent movement with respect to the plunger. The needle portion includes a hollow needle configured to allow both the object and the fluid to pass out of the needle and into the patient's tissue. The needle portion may include a housing located behind the needle that is configured to hold the solid object. Once the needle portion and the syringe portion are coupled together, the device is operated in accordance with methods of the present invention to effectively co-inject the patient with the object and the amount of fluid.Type: GrantFiled: May 17, 2007Date of Patent: August 31, 2010Inventor: Lester M. Schwab
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Patent number: 7780625Abstract: An implantation instrument for implanting a substantially solid material, including solid medication or drugs, in a subcutaneous location and method are described. An incising shaft includes a beveled tip with a cutting edge along a distal end. A syringe body is affixed to a proximal end of the incising shaft. The syringe body and the incising shaft each define a substantially non-circular hollow bore extending continuously along a shared longitudinal axis. The incising shaft bore does not exceed the syringe body bore in girth. Both the incising shaft bore and the syringe body bore are sized to receive the solid material. A plunger is conformably shaped to the syringe body bore and has an end piece facilitating deployment of the plunger assembly. The plunger slidably fits within the syringe body bore and advances the solid material through the syringe body bore and the incising shaft bore into the subcutaneous location.Type: GrantFiled: February 1, 2006Date of Patent: August 24, 2010Inventor: Gust H. Bardy
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Patent number: 7782189Abstract: A system for monitoring ingestion of medicine (21) comprises forming a digestible radio frequency identification (RFID) tag (10). The RFID tag is attached to the medicine. The RFID tag and medicine are ingested. A signal from the RFID tag is monitored.Type: GrantFiled: February 9, 2006Date of Patent: August 24, 2010Assignee: Carestream Health, Inc.Inventors: John P. Spoonhower, Edward Covannon
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Publication number: 20100204678Abstract: Embodiments described herein provide a skin penetrating device and method for the subcutaneous delivery of therapeutic agents in solid form. One embodiment provides such a device comprising an elongated shaft having proximal and distal ends and a skin penetrating element detachably coupled to the shaft. At least a portion of the penetrating element is fabricated from a solid form therapeutic agent composition that dissolves in body tissue and is absorbed into the blood stream so as to produce a therapeutic effect. The penetrating element has shape for penetrating and lodging beneath the skin when inserted through the skin by force applied from the shaft. The penetrating element is configured to detach from the shaft when the shaft is pulled away from the skin so as to leave the element in place beneath the skin where it is absorbed by body tissue and the therapeutic agent is released.Type: ApplicationFiled: February 12, 2010Publication date: August 12, 2010Inventor: Mir Imran
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Patent number: 7753872Abstract: A device, system and method for improving delivery of hemostatic material, in which the device includes a vent cap body capable of removably engaging a cannula. The vent cap has a passage extending through the vent cap body from the cannula to an exterior of the vent cap body where a restricter for restricting the flow of fluid from the cannula to the exterior. In one embodiment, the vent cap has a valve which has an opened and closed position. In the closed position, the valve is designed to provide a back pressure or resistance. When a certain force is applied against the valve, the valve moves from the closed position to the opened position, where a gas or fluid may pass through the vent cap. The vent cap is designed to help maintain the continuity of the hemostatic material during delivery of the material from the adaptor to the trial staging chamber.Type: GrantFiled: January 29, 2003Date of Patent: July 13, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Andrew H. Cragg, Rodney Brenneman, Mark Ashby