Abstract: A medical electrical lead system includes an electrical signal generator providing a plurality of discrete electrical signal channels and an electrical signal channel router electrically coupled between the electrical signal generator and a first lead body and a second lead body. The electrical signal channel router diverts one of the discrete electrical signal channels to the second lead body and not to the first lead body.

Abstract: A method of treating a patient and an external programmer for use with a neurostimulator. Electrical stimulation energy is conveyed into tissue of the patient via a specified combination of a plurality of electrodes, thereby creating one or more clinical effects. An influence of the specified electrode combination on the clinical effect(s) is determined. An anatomical region of interest is displayed in registration with a graphical representation of the plurality of electrodes. The displayed anatomical region of interest is modified based on the determined influence of the specified electrode combination on the clinical effect(s).

Abstract: The invention comprises an elongated device adapted for insertion, including self-insertion, through the body, especially the skull. The device has at least one effector or sensor and is configured to permit implantation of multiple functional components through a single entry site into the skull by directing the components at different angles. The device may be used to provide electrical, magnetic, and other stimulation therapy to a patient's brain. The lengths of the effectors, sensors, and other components may completely traverse skull thickness (at a diagonal angle) to barely protrude through to the brain's cortex. The components may directly contact the brain's cortex, but from there their signals can be directed to targets deeper within the brain. Effector lengths are directly proportional to their battery size and ability to store charge. Therefore, longer angled electrode effectors not limited by skull thickness permit longer-lasting batteries which expand treatment options.

Abstract: A method for providing electrical stimulation to a user as a user performs a set of tasks during a time window, the method comprising: providing an electrical stimulation treatment, characterized by a stimulation parameter and a set of portions, to a brain region of the user in association with the time window; for each task of the set of tasks: receiving a signal stream characterizing a neurological state of the user; from the signal stream, identifying a neurological signature characterizing the neurological state associated with the task; and modulating the electrical stimulation treatment provided to the brain region of the user based upon the neurological signature, wherein modulating comprises delivering a portion of the set of portions of the electrical stimulation treatment to the brain region of the user, while maintaining an aggregate amount of the stimulation parameter of the treatment provided during the time window below a maximum limit.

Abstract: An electrical neuromodulation system configured for minimizing energy consumption of a neuromodulation device includes an external control device configured for receiving input from a user, the neuromodulation device in communication with the external control device, and control/processing circuitry. The control/processing circuitry is configured for automatically (a) adjusting a modulation parameter value (e.g., by a step size) to create a currently adjusted modulation parameter value that decreases the energy consumption of the neuromodulation device, (b) instructing the neuromodulation device to deliver electrical energy to at least one electrode in accordance with the currently adjusted modulation parameter value, (c) determining whether a manual parameter adjustment was made by the user in response to step (b), and (d) if the manual parameter adjustment was not made, deeming the currently adjusted modulation parameter value as a previously adjusted modulation parameter value and repeating steps (a)-(d).

Abstract: A method is provided that includes disposing midplane treatment electrodes over a superior sagittal sinus, outside and in electrical contact with a skull of a head of a subject identified as at risk of or suffering from Alzheimer's disease. Lateral treatment electrodes are disposed between 1 and 12 cm of a sagittal midplane of the skull. The subject is treated by electroosmotically driving fluid from a subarachnoid space to the superior sagittal sinus, by activating control circuitry to apply one or more treatment currents between (a) one or more of the midplane treatment electrodes and (b) one or sore of the lateral treatment electrodes. Other embodiments are also described. Other embodiments are also described.

Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.

Abstract: A monitoring system may include each of a left and a right side EMG detection device and may be configured to detect either seizure activity associated with the left side or right side of a patient's body. The system may further be configured to differentiate symmetric or asymmetric seizure activity. For example, the system may characterize whether left and right side EMG detectors show similar or dissimilar levels of activation during a suspected seizure. In some embodiments, the system may also include one or more orientation and/or position sensors. The system may be configured to determine the orientation and position of the sensor over time and to correlate this data with EMG signals.

Abstract: An implantable medical device includes a low-power circuit and a multi-cell power source. The cells of the power source are coupled in a parallel configuration. The implantable medical device includes both a low power circuit that is selectively coupled between the first and second cells and a high power output circuit that is directly coupled to the first and second cells in a parallel configuration. An isolation circuit is coupled to the first cell, the second cell and the low power circuit to maintain a current isolation between the first cell and the second cell at least during delivery currents having a large magnitude that are delivered to the high power output circuit.

Abstract: A method and system of remotely stimulating the midbrain area is disclosed. Transcranial direct current stimulation is applied via a cathode attached to the right dorsolateral prefrontal cortex and an anode attached to the ventromedial prefrontal cortex. These regions are either directly connected or indirectly connected to the midbrain region. The stimulation allows non-invasive stimulation of neurons in the midbrain region to address brain disorders such as Parkinson's disease, schizophrenia, depression and addiction.

Abstract: In a patient suffering from neural impairment, stimulation is provided to sensory surfaces of the face and/or neck, or more generally to areas of the body that stimulate the trigeminal nerve, while performing an activity intended to stimulate a brain function to be rehabilitated. The simulation may then be continued after the performance of the activity has ceased. It has been found that the patient's performance of the activity is then improved after stimulation has ceased. Moreover, it tends to improve to a greater extent, and/or for a longer time, when the post-activity stimulation is applied, as compared to when postactivity stimulation is not applied.

Abstract: A method is disclosed for desynchronizing neuronal brain activity of a patient in which the brain activity involves a neuron population firing in a synchronized manner. The method includes measuring a pathological frequency g of the neuronal brain activity of the patient, where the pathological frequency g relates to a pathological disorder of the patient. The method further includes calculating a stimuli frequency f based on the measured pathological frequency g, where the stimuli frequency f is calculated as being equal to the measured pathological frequency g×n/m, where n is 1, 2 or 3 and m is 1, 2 or 3, and controlling an electrode to generate stimuli in sequence with the stimuli succeeding each other at the stimuli frequency f, where the stimuli stimulate the neuron population of the patient.

Abstract: A patient feedback device for use in an electrical stimulation system is calibrated. The electrical stimulation system includes an implantable pulse generator (IPG) implanted in a patient and a patient feedback device having a force sensor. Input from the patient is sensed using the patient feedback device. At a first time, an electrical stimulus is applied with the IPG. The force sensor is monitored at a plurality of time points. A level of force sensed by the force sensor at each of the plurality of time points is recorded. A time point at which a maximum force is applied is identified, or a time point at which a minimum force is applied is identified. The first time is compared to the time point at which a minimum force is applied or the time point at which a maximum force is applied, in order to determine a patient response time.

Abstract: The present invention relates to a method to control a thalamic projecting fiber in a subject. This method involves providing a subject having a first stimulator and a second stimulator implanted in the subject's central thalamus. A stimulus signal generator is provided which is coupled to the first and second stimulators. Separate stimulus signals are provided from the stimulus signal generator to the first and second stimulators under conditions effective to control the thalamic projecting fiber in the subject. Also disclosed is an apparatus for deep brain stimulation.

Abstract: A method for personalized patient controlled neurostimulation is disclosed. The method generally includes steps (A) to (D). Step (A) may obtain (i) physical data of an individual and (ii) one or more manual inputs from the individual. Step (B) may generate compare data in a processor circuit by comparing the physical data with profile data of the individual. Step (C) may generate customized data by processing the one or more manual inputs and the compared data using a set of rules. The rules are generally (i) reprogrammable and (ii) govern generation of a nerve stimulation signal having predetermined control characteristics applicable to the individual. Step (D) may control the neurostimulation of the individual with the nerve stimulation signal based on the customized data.

Abstract: Described herein are devices, systems, and methods for wireless power transfer utilizing a midfield source and implant. In one variation, a midfield source may be realized by a patterned metal plate composed of one of more subwavelength structures. These midfield sources may manipulate evanescent fields outside a material (e.g., tissue) to excite and control propagating fields inside the material (e.g., tissue) and thereby generate spatially confined and adaptive energy transport in the material (e.g., tissue). The energy may be received by an implanted device, which may be configured for one or more functions such as stimulation, sensing, or drug delivery.

Abstract: Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency.

Abstract: A system and method for delivering coupled burst and tonic stimulation of nervous tissue is provided. The system and method includes providing a lead with at least one stimulation electrode configured to be implanted at a target position proximate to nervous tissue of interest. The system and method further includes coupling the lead to an implantable pulse generator (IPG). The method delivers a first current pulse configured as a tonic stimulation waveform to the at least one electrode. The tonic stimulation waveform is configured to excite A-beta fibers of the nervous tissue. After a tonic-burst delay, the IPG delivers second current pulses configured as a burst stimulation waveform to at least one electrode. The burst stimulation waveform is configured to excite C-fibers of the nervous tissue.

Abstract: A neurostimulation device is provided comprising an input, a neurostimulation probe, a stimulation unit and a distribution calculation module. At the input stimulation data is received comprising information relating to a stimulation preferability and an orientation of at least one fiber bundle. The neurostimulation probe comprises an array of stimulation electrodes which are coupled to the stimulation unit. The stimulation unit, in accordance with a specified current distribution, provides currents to the respective stimulation electrodes for generating an electric field gradient. The distribution calculation module is coupled to the input and the stimulation unit for based on the stimulation data determining a preferred position and orientation for the electric field gradient, and based on the preferred position and orientation for the electric field gradient, calculating the specified current distribution.

Abstract: The present disclosure describes a medical device to provide neurostimulation therapy to a patient's brain. The device can be surgically implanted and can remain in the patient until end of life. The present disclosure also describes accessories which guide the implantation of the device, and the components that form a leadless stimulator implantation kit.

Abstract: The present invention provides methods, devices, and systems for restoring or improving nervous system function of a subject. Provided is a method involving: (i) providing an operant conditioning protocol effective to produce targeted neural plasticity (TNP) in a primary targeted central nervous system (CNS) pathway of a subject; and (ii) administering the operant conditioning protocol to the subject to elicit TNP in the primary targeted CNS pathway and to elicit generalized neural plasticity (GNP) in one or more other CNS pathway. The elicitation of the GNP in the one or more other CNS pathway serves to restore or improve a nervous system function of the subject. Provided is a device comprising a nerve stimulation-electromyographic recording component and a controller for operating the nerve stimulation-electromyographic recording component in accordance with an operant conditioning protocol.

Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition in a patient using an implantable medical device by applying an electrical signal characterized by having a number of pulses per microburst, an interpulse interval, a microburst duration, and an interburst period to a portion of a cranial nerve of said patient, wherein at least one of the number of pulses per microburst, the interpulse interval, the microburst duration, or the interburst period is selected to enhance cranial nerve evoked potentials.

Abstract: A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.

Abstract: The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.

Abstract: What is disclosed is a system and method for detecting febrile seizure using a thermal video camera. In one embodiment, a video is received comprising time-sequential thermal images of a subject. The video is acquired of the subject in real-time using a thermal video system. Each thermal image comprises a plurality of pixels with an intensity value of each pixel corresponding to a temperature. The thermal images are processed to determine an occurrence of a febrile seizure. The processing involves identifying a region of interest in the thermal image and determining a temperature for the region of interest based on values of the pixels isolated in that region of interest. Thereafter, a rate of change of temperatures is obtained for the subject in real-time on a per-frame basis. If the rate of change is determined to have exceeded a pre-defined threshold level, then the subject is having a febrile seizure.

Abstract: A method for treating a patient suffering from loss of muscle control and/or function in a body region after a stroke includes epidurally applying electrical stimulation to a spinocerebellar tract of the patient (e.g., at or above the vertebral level of the spinal cord where the sensory and motor mapping for the body region are located), thereby increasing cortical excitability and facilitating the patient regaining muscle control and/or function in the body region. The method may include using cortical mapping to determine a cortical region having a residual motor response in or near the body region, implanting an electrode in a lateral epidural space, and applying the electrical stimulation in a manner that causes excitability in the cortical region having the residual motor response, wherein the stimulation is applied by the implanted electrode. The method may include exercising the body region while simultaneously applying the electrical stimulation.

Abstract: Example ionic coupling electrodes are described. One example ionic conducting electrode includes a first portion that can be coupled to a single phase current source. The first portion carries current flow via electrons. The electrode includes a second portion to apply a current to a nerve tissue. The second portion carries current flow via ions. The second portion is positioned between the nerve tissue and the first portion to prevent the first portion from touching the nerve tissue. The current applied to the nerve tissue is produced in the second portion in response to a current that is present in the first portion. The current present in the first portion is provided from a single phase current source. The electrode may be used in applications including, but not limited to, nerve block applications and nerve stimulation applications.

Abstract: The invention relates to an apparatus (1) for stimulating neurons having a pathological synchronous and oscillatory neural activity, said apparatus comprising a non-invasive stimulation unit (11) for applying stimuli (22) that stimulate a patient's neurons, a measurement unit (12) for recording test signals (23) that represent a neural activity of the stimulated neurons, and a control and analysis unit (10) for controlling the stimulation unit (11) and analyzing the test signals (23).

Abstract: The present application involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communication with a predetermined site which is coupled to a signal generator and/or infusion pump that release either an electrical signal and/or a pharmaceutical resulting in stimulation of the predetermined site thereby treating the mood and/or anxiety.

Abstract: A method for manufacturing a lead includes forming an elongated multi-lumen conductor guide defining a central stylet lumen and a plurality of conductor lumens arranged around the stylet lumen. The multi-lumen conductor guide is twisted to form at least one helical section where the plurality of conductor lumens each forms a helical pathway around the stylet lumen. Each of the helical pathways of the at least one helical section has a pitch that is no less than 0.04 turns per centimeter.

Abstract: A noninvasive brain computer interface (BCI) system includes an electroencephalography (EEG) electrode array configured to acquire EEG signals generated by a subject. The subject observes movement of a stimulus. A computer is coupled to the EEG electrode array and configured to collected and process the acquired EEG signals. A decoding algorithm is used that analyzes low-frequency (delta band) brain waves in the time domain to continuously decode neural activity associated with the observed movement.

Abstract: A brain machine interface (BMI) for restoring performance of poorly performing decoders is provided. The BMI has a decoder for decoding neural signals for controlling the brain machine interface. The decoder separates in part neural signals associated with a direction of movement and neural signals associated with a speed of movement of the brain machine interface. The decoder assigns relatively greater weight to the neural signals associated with a direction of movement.

Abstract: Various implantable device embodiments may comprise a neural stimulator configured to deliver a neurostimulation therapy with stimulation ON times and stimulation OFF times where a dose of the neurostimulation therapy is provided by a number of neurostimulation pulses over a period of time. The neural stimulator may be configured to monitor the dose of the delivered neurostimulation therapy against dosing parameters. The neural stimulator may be configured to declare a fault if the monitored dose does not favorably compare to a desired dose for the neurostimulation therapy, or may be configured to record data for the monitored dose of the delivered neurostimulation therapy, or may be configured to both record data fir the monitored dose of the delivered neurostimulation therapy and declare a fault if the monitored dose does not favorably compare to a desired dose for the neurostimulation therapy.

Abstract: In one embodiment, a method of treating an eating disorder in a patient, comprises: diagnosing the eating disorder in the patient; and electrically stimulating a subgenual cingulate cortex site or a ventral medial prefrontal cortex site in the patient using electrodes of an implanted stimulation lead.

Abstract: A method includes storing baseline data representing at least one local or global electrical characteristics for at least a portion of a region of interest (ROI) of a patient's anatomical structure. The baseline data is determined based on electrical measurement data obtained during at least one first measurement interval. The method also includes storing in memory other data representing the at least one local or global electrical characteristics for the at least a portion of the ROI based on electrical measurement data obtained during at least one subsequent measurement interval. The method also includes evaluating the baseline data relative to the other data to determine a change in the at least one local or global electrical characteristics. The method also includes generating an output based on the evaluating to provide an indication of progress or success associated with the applying the treatment.

Abstract: A neurostimulation system for management of stimulation safety limits. The system determines a tissue charge injection metric at each electrode, compares the metric to the hard stop charge limit, and prevents the neurostimulator from delivering stimulation energy to the tissue region in accordance based on the comparison. The hard stop limit may be user-programmable or may be automatically modified in response to detection of electrode characteristics. The system may quantitatively notify a user of a value of the injected charge injected into the tissue. The electrodes may be organized into different sets, in which case, the system may directly control tissue charge independently at each of the electrode sets. If current steering is provided, the system may displace the electrical stimulation energy along the tissue region in one direction, while preventing the charge injection value at each of the electrodes from meeting or exceeding the hard stop charge limit.

Abstract: A method, system and apparatus is presented for a wireless neural modulation feedback control system as it relates to an implantable medical device comprised of a radio frequency (RF) receiver circuit, one or more dipole or patch antenna(s), one or more electrode leads connected to at least one dipole or patch antenna(s), and at least one microelectronic neural modulation circuit, and an external or internally implanted RF device to neurally modulate brain tissue in order to treat medical conditions that can be mediated by neuronal activation or inhibition, such as Parkinson's, Alzheimer's, epilepsy, other motor or mood based disorders, and/or pain. The implantable receiver captures energy radiated by the RF transmitter unit and converts this energy to an electrical waveform by the implanted neural modulation circuit to deliver energy that can be utilized by the attached electrode pads in order to activate targeted neurons in the brain.

Abstract: A Medical Device Application (MDA) is disclosed for an external device (e.g., a cell phone) that can communicate with an Implantable Medical Device (IMD). The MDA receives data logged in the IMD, processes that data in manners reviewable by an IMD patient, and that can control the IMD based on such processed data. The MDA can use the logged data to adjust IMD therapy based on patient activity or posture, and allows a patient to learn optimal therapy settings for particular activities. The MDA can also use the logged data to allow a patient to review details about IMD battery performance, whether such battery is primary or rechargeable, and to control stimulation parameters based on that performance. The MDA also allows a patient to enter medicine dose information, to review the relationship between medicinal therapy and IMD therapy, and to adjust IMD therapy based on the dosing information.

Abstract: A neurostimulation patch is affixed to a patient's skin (e.g., via a medical skin adhesive) and provides stimulation energy for an implanted lead. The patch may be used for SCS trials or other applications where is it desirable to avoid implanting a stimulation device within a patient. Circuitry in the patch generates stimulation signals and couples these signals to the implanted lead. The signals may be coupled to the lead via a direct physical connection or via a wireless connection. In some embodiments, the neurostimulation patch is configured in a manner that enables the patch to be placed immediately above the puncture site where an associated percutaneous lead passes through a patient's skin, thereby protecting the puncture site and facilitating secure routing of the lead.

Abstract: Devices, systems and methods for treating medical disorders, such as migraine or other primary headaches, or fibromyalgia, by noninvasive electrical stimulation of a vagus nerve, used in conjunction with the measurement of evoked potentials (EPs). The system comprises a stimulator that is applied to the surface of the patient's neck to apply electrical impulses sufficient to stimulate a cervical vagus nerve, scalp electrodes that are used to measure EPs that are evoked by that stimulation, feedback or biofeedback circuits to vary the stimulation based upon EP characteristics, and other sensory stimulation modalities that produce EPs. The system is preferably used to optimize the placement of the stimulator, to test whether a patient is a suitable candidate for treatment using vagus nerve stimulation, and to select the stimulation parameters that optimized acute or chronic treatment, e.g., by correcting an EP habituation deficit.

Abstract: Systems and methods for treating a neurological disorder comprising determining a first set of neural stimulation parameters capable of treating a first subset of symptoms, determining a second set of neural stimulation parameters capable of treating a second subset of symptoms, and applying a neural stimulation therapy based upon the first set of neural stimulation parameters and the second set of neural stimulation parameters to the patient. The first set of neural stimulation parameters can include electrical stimulation at a first frequency, and the second set of neural stimulation parameters can include electrical stimulation at a second frequency. In other embodiments, a treatment method comprises applying a first neural stimulation therapy to the patient in a continuous or generally continuous manner during a first time interval, and applying a second neural stimulation therapy to the patient in a noncontinuous or interrupted manner following the first time interval.

Abstract: A neuromodulation system and method for managing electrical neuromodulation therapy for a patient in conjunction with administering a pharmacological agent to the patient. Electrical energy is delivered to a target tissue region of the patient, thereby electrically modulating the target tissue region providing therapy to the patient. The energy level of the electrical energy delivered to the tissue is automatically varied inversely to the effect of the pharmacological agent on the patient during a therapeutic window. An absorption level of the pharmacological agent in the patient may be continually detected, and the energy level of the delivered electrical energy automatically varied based on the detected absorption level of the pharmacological agent during a therapeutic window.

Abstract: A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more intracranial (IC) stimulating electrodes in accordance with treatment parameters. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

Abstract: Methods of treating a medical condition include applying at least one stimulus to a motor cortex within a brain of a patient with an implanted system control unit in accordance with one or more stimulation parameters. Systems for treating a medical condition include a system control unit implanted within the patient that is configured to apply at least one stimulus to a motor cortex within a brain of a patient in accordance with one or more stimulation parameters.

Abstract: Described are devices including stimulation assemblies connectable to a plurality of electrodes. The plurality of electrodes can be configured to connect to a spinal cord at a location below a lesion of the spinal cord. The stimulation assembly can be configured to deliver stimulation to selected ones of the plurality of electrodes when the stimulation assembly is connected to the plurality of electrodes when located below the lesion of the spinal cord. Methods of using the devices are also described.

Abstract: An auditory stimulation signal processing device includes a plurality of signal inputs adapted to receive a plurality of frequency bin signals; a signal selector adapted to select a selected frequency bin signal from the plurality of frequency bin signals; a parameter modifier adapted to vary at least one stimulation signal generation parameter used for generating an electrode stimulation signal and affecting a shape of a basic stimulation pulse; and an electrode stimulation signal generator adapted to generate the electrode stimulation signal for application to an electrode of a neural auditory prosthesis, the electrode corresponding to a frequency of the selected frequency bin signal. A corresponding method and a computer readable digital storage medium are also disclosed.

Abstract: The present disclosure describes a medical device to provide neurostimulation therapy to a patient's brain. The device can be surgically implanted and can remain in the patient until end of life. The present disclosure also describes accessories which guide the implantation of the device, and the components that form a leadless stimulator implantation kit.

Abstract: An electrical neuromodulation system and method of treating an ailment of a patient using a neuromodulation device. Electrical modulation energy is delivered at a first frequency from the neuromodulation device to a first set of electrodes having a first combined electrode impedance. A second set of electrodes having a second combined electrode impedance less than the first combined electrode impedance is automatically selected. The electrical modulation energy is delivered at a second frequency to the second set of electrodes, wherein the second frequency is greater than the first frequency.

Abstract: A method may include sensing a time of beat sequence of a patient's heart and processing said time of beat sequence with a medical device to identify a change in heart rate of a patient from a first heart rate to a second heart rate. The method may continue by determining with the medical device at least one of a) a ratio of the second heart rate to the first heart rate and b) a difference between the second heart rate and the first heart rate. The method may include determining with the medical device at least one of a) a dynamic ratio threshold for the ratio and b) a dynamic difference threshold for the difference, wherein the at least one threshold is based upon the first heart rate. The ratio and/or the difference may be compared to the threshold(s) to detect a neurological event, for example, an epileptic seizure.

Abstract: The implantable medical device is for implantation into a patient's body and is wirelessly powered by an external control device. The implantable medical device is induced by an AC electromagnetic field of the external control device through an inductive coil. A rectifier converts the AC electromagnetic field into a DC current. A detector detects a voltage value of the DC current, and a processor produces a first piece of status information accordingly. A transceiver receives and relays the first piece of status information to the external control device so as to monitor the power consumption of the implantable medical device when it is wirelessly powered.