Abstract: Embodiments of systems and methods for an integrated phototherapy system that can include integrating a bili light, radiometer, and transcutaneous bilirubin sensor are disclosed. In some embodiments, the integrated phototherapy system has a control system that can receive and send data and automate features of the phototherapy system. Data that can be input by a healthcare provider and/or measured by the system can include treatment time, distance between the patient and the bili light, intensity level, irradiance level, bilirubin level, temperature, and the light intensity or irradiance of other light sources or pieces of equipment. The phototherapy system can be compatible with any electronic healthcare records system, and measured data can aggregated and uploaded to such a system.

Abstract: A method for at-home skin condition analyses includes coupling an adapter to a port of a wearable lamp platform. placing the wearable lamp platform on a portion of a user's body, coupling a data acquisition device to the adapter and activating the data acquisition device to acquire data pertaining to the user's body through the optical lens, analyzing the data pertaining to the user's body, determining a light treatment regimen for the user's body, and applying light treatment to the user's body according to the determined light treatment regimen. The port has disposed therein an optical lens and having a plurality of image image-acquisition lamps disposed thereabout. The image-acquisition lamps are energized by a power source electrically coupled to the wearable lamp platform, and the wearable lamp platform comprises a plurality of treatment lamps arranged and configured to irradiate a portion of a wearer's body.

Abstract: The present invention relates to a handheld device (1) which is used for performing a treatment action while being moved along a treatment surface (4). The result of the treatment action is dependent on the angular position (?) in which the device (1) is being held relative to the treatment surface. An example of such a device is an epilator for removing hairs from a surface of the user's skin. The device comprises at least two light sources (5) arranged and adapted to each provide a delimited light spot (6) on the treatment surface or on an outer surface of the device when the device is in operation. The two or more light sources (5) are arranged so that the light spots (6) they provide are at least partially coincident when the device is held at an angular position relative to the treatment surface which is within a predetermined optimal range of angular positions for which the treatment action is optimal.

Abstract: A light source apparatus including a light-emitting module and a control unit is provided. The light-emitting module is configured to provide a light. The control unit is configured to make the light switched between a first light and a second light so that at least one of a blue-light hazard and a circadian stimulus value of the light is changed. A wavelength of a blue light main peak in a spectrum of the first light is different from a wavelength of a blue light main peak in a spectrum of the second light.

Abstract: An embodiment of the disclosure provides a light source apparatus including a light-emitting module and a control unit. The light-emitting module is configured to provide a light. The control unit is configured to change proportion of a first sub-light and a second sub-light to form the light so that a circadian action factor (CAF) and a correlated color temperature (CCT) of the light varies along a CAF vs. CCT locus of the light different from a CAF vs. CCT locus of sunlight. A CAF vs. CCT coordinate of one of the first sub-light and the second sub-light is below the CAF vs. CCT locus of sunlight, and a CAF vs. CCT coordinate of the other one of the first sub-light and the second sub-light is above the CAF vs. CCT locus of sunlight. A display apparatus is also provided.

Abstract: A light source unit includes a blue light source configured to output light in a blue wavelength range, an excitation light source configured to emit excitation light having a shorter wavelength than a wavelength of the light in the blue wavelength range outputted from the blue light source, and a luminescent wheel including a luminescent light emitting area on to which the excitation light is shined to thereby emit luminescent light and a light guiding area configured to transmit or reflect the light in the blue wavelength range, and the excitation light is shined on to the luminescent light emitting area from a first surface side of the luminescent wheel, and the light in the blue wavelength range is shined on to the light guiding area from a second surface side of the luminescent wheel that is opposite to the first surface side.

Abstract: Apparatus and methods for producing narrow-band radiation in the green region of the visible spectrum are described. The narrow-band radiation may be used to aid subjects experiencing photophobia. In some cases, subjects may experience a reduction in pain (e.g., migraine photophobia) when using the narrow-band radiation.

Abstract: This disclosure provides a laser acupuncture apparatus and a laser acupuncture device. The laser acupuncture apparatus includes: a bracket; an acupuncture unit movably installed on the bracket, where the acupuncture includes at least one laser emitter; an image capturer installed on the bracket; and a control unit coupled to the acupuncture unit and the image capturer, where the control unit is configured to analyze an image acquired by the image capturer, and to control the acupuncture unit according to an image analysis result to move relative to the bracket.

Abstract: A portion of a treatment device for treating bacteria may be coupled with the bacteria through direct or indirect contact. Mechanical stress energy and electromagnetic energy are generated with the treatment device, and are transmitted from the treatment device to the bacteria during the coupling. The bacteria are treated with both the mechanical stress energy and the electromagnetic energy to produce a killing effect on the bacteria. A treatment device may include a mechanical stress energy emitting portion, an electromagnetic energy emitting portion, and a contacting portion for coupling into direct or indirect contact with the bacteria and transmitting mechanical stress energy to the bacteria during the coupling. The mechanical stress energy emitting portion and the electromagnetic energy emitting portion are operable to treat the bacteria with a combination of mechanical stress energy and electromagnetic energy to produce a killing effect on the bacteria.

Abstract: According to a first aspect disclosed herein, there is provided a controller for controlling a first light source to emit light into a pupil of a human user in order to reduce at least one biological effect of light from a second light source on the human user, the controller comprising: a first input for receiving light property data indicating a property of the light from the second light source, said property being of a type which causes a biological effect on the human user; a second input for receiving pupil data indicating a size of the pupil of the human user; an output for sending control commands to the first light source; a processor configured to: determine, using the light property data received via the first input, that the light from the second light source has said property; in response to said determination that the light from the second light source has said property, determine, using said pupil data received via the second input, a current size of the pupil; and on condition that the current

Abstract: The newly discovered retinal ganglion cell photoreceptor melanopsin absent in the central fovea of the eye but distributed throughout the remaining human retinal body provides both non-visual biological/physiological input inducing circadian entrainment, and visual input affecting perceived brightness; this perceived brightness is not the object brightness commonly associated with luminance and perceived color of an object in central view, but the perception of brightness of a whole space or task background.

Abstract: An apparatus and method of use for a comprehensive transcranial low-level light therapy for use with ischemic brain tissue using a multitude of polychromatic Light Emitting Diodes (LEDs) embedded into a flexible head covering that stretches securely around the patient's cranium to bath the entire cranium cavity in a variable frequency, variable power density light spectrum, maximizing all beneficial effects to the cellular tissues whether or not they are specifically deprived of blood from the ischemic stroke event. The bulbs covering the n-p junction of the semiconductor LEDs directly contact the patient's cranial skin to maximize the depth of penetration of the wavelengths into the brain's cortex cells. By using many individual point-source LEDs emitting all around the cranium, greater therapeutic benefit can be achieved as more of the cortex tissues are irradiated.

Abstract: A wearable light emitting apparatus for eyebrow growth is provided. The wearable light emitting apparatus for eyebrow growth comprises a main body and at least one light emitting assembly. The main body is to be wore on an user's head. The at least one light emitting assembly is located on the main body for projecting at least an eyebrow-shaped light beam to an eyebrow growing area of the head when the main body is wore on the user's head.

Abstract: Various embodiments of and methods for providing therapeutic light or electromagnetic radiation stimulation to a patient are disclosed and described. Therapeutic light stimulation is provided to a patient through a light source, and is configured to trigger or induce resonance or high amplitude oscillations in a cardiovascular system of the patient. Inducing such oscillations or resonance can aid in training autonomic reflexes and improve their functioning.

Abstract: A phototherapy device comprises a face mask having a rigid (or semi-rigid) shell contoured to the human face. A flexible array of LEDs is affixed to the inner surface of the mask. A flexible, quantum dot-containing film is situated over the flexible array of LEDs. The quantum dots in the QD-containing film are selected to photo-luminesce at one or more particular wavelengths in response to photoexcitation by the light emitted from the LEDs. The LEDs emit “primary light” and the quantum dots down-convert at least a portion of the primary light to “secondary light.” The flexible, quantum dot-containing film may be interchangeable such that the wavelength(s) of the secondary light may be tailored to various phototherapy treatment regimes.

Abstract: The present disclosure provides systems and methods for imaging-guided monitoring and modeling of retinal vascular occlusive conditions. An example integrated optical coherence tomography (OCT) and scanning laser ophthalmoscope (SLO) apparatus includes an OCT subsystem to acquire baseline OCT and OCT angiography (OCTA) volumes of a subject without dye before occlusion and subsequent OCT and OCTA volumes of the subject with dye after occlusion. The example apparatus includes an SLO subsystem including a laser controlled to adjust a laser to form a vascular occlusion at a location on a target vessel of the subject. The example apparatus includes a processor to process the OCT and OCTA volumes and feedback from the OCT subsystem and the SLO subsystem to determine a change in three-dimensional vasculature from before the vascular occlusion to after the vascular occlusion.

Abstract: A technique for performing a visual field test on an eye includes sequentially presenting visual stimuli to the eye on a display. A gaze direction of the eye is monitored with a camera to identify when the gaze direction has drifted from a fixation target. A first intended position associated with a first visual stimulus of the visual stimuli is offset to compensate for drifting of the gaze direction from the fixation target when the gaze direction is determined to have drifted during presentation of the first visual stimulus. User inputs indicating whether the user acknowledges observance of each of the visual stimuli presented are registered.

Abstract: Provided are dermatological medical devices and methods comprising a distal end for positioning at a region proximal a target therapeutic region of tissue, an output port at the distal end, an energy source that generates optical energy, which is output from the output port to the target therapeutic region of tissue, and a control device that controls the optical energy at the target therapeutic region of tissue for increasing a temperature of the target therapeutic region of tissue for a period of time to a temperature that is less than an injuring temperature and induces an expression of heat shock proteins (HSPs) at the target therapeutic region of tissue.

Abstract: A handheld device, including: (a) a housing including a grip portion and a head portion; (b) at least one radiofrequency (RF) contact disposed on the head portion; and (c) a capsule holder adapted to hold a capsule in a coupling arrangement.

Abstract: Systems and methods for performing magnetic resonance (MR) thermometry include a magnetic resonance imaging (MRI) unit and a controller in communication with the MRI unit and configured to cause the MRI unit to acquire one or more baseline phase images of an imaging region and one or more treatment phase images of the imaging region subsequent to a temperature change of a subregion within the imaging region, electronically generate a thermal map pixelwise indicating the temperature change of the subregion based at least in part on the acquired baseline phase image and treatment phase image, computationally predict the temperature change of the subregion based at least in part on energy deposited in the subregion during treatment without reference to the generated thermal map, and determine whether the thermal map is inaccurate based at least in part on the temperature change of the subregion indicated by the thermal map and the predicted temperature change of the subregion.

Abstract: This invention relates to a source for emitting radiation in the infrared range comprising a thin membrane including a radiation element made from a semi-conductive material having a chosen dopant, the radiation element being connected to a frame, the frame comprising connector means for connecting to a power source for conducting an electrical current through the substrate, the radiation element being provided with a periodic modulation of the refractive index constituting a photonic crystal having a chosen period, thus defining an optical resonator at one or more chosen wavelengths, and wherein the membrane is mounted to the substrate through a number of conductor beams distributed along the membrane circumference so as to provide an even current distribution and thus even heating over the membrane.

Abstract: A treatment device configured to illuminate a surface of a 3D skin surface when positioned adjacent the illuminated surface of the 3D skin surface. The treatment device includes a number of linear light source strips to conformally illuminate the 3D skin surface.

Abstract: The present invention is directed to a system and method for photoeradication of microorganisms from a target. A light source is configured to irradiate the target with purple or blue light in a pulsed mode of irradiation at an average irradiance that preferably ranges from 0.1 mW/cm2 to 20 mW/cm2. An electronic circuit is configured to control the light source in accordance with an irradiation schedule that includes a plurality of irradiation sessions. The light source is controlled to provide the purple or blue light at a radiant exposure that preferably ranges from 0.5 J/cm2 to 60 J/cm2 during each of the irradiation sessions. The irradiation sessions are provided at a plurality of time intervals so as to cause photoeradication of all or a portion of the microorganisms.

Abstract: One bracelet embodiment provides therapeutic blood irradiation at a first wrist region using a first module, and body temperature regulation/irradiation at a second wrist region using a second module. A connector couples one end of the modules together, while an attachment band releasably couples the second ends together, for attachment to the wrist. The first module includes first and second distributed pluralities of lights respectively emitting 850 and 660 nm wavelengths, and a third plurality emitting 630 nm, 532 nm, and 450 nm wavelengths, positioned in a row substantially parallel to the arm of the user. The second module includes first and second rows of lights on first and second sides of a cooling unit, each emitting 405 nm wavelengths, with the two rows positioned for penetration to the radial and ulnar arteries. The bracelet includes a microprocessor, LED screen, and firmware for displaying a GUI permitting treatment protocol selections.

Abstract: An apparatus for treatment of a subcutaneous fat region includes a source of electromagnetic radiation generating electromagnetic radiation having a non-fat selective wavelength. A delivery system is coupled to the source of electromagnetic radiation and is configured to deliver the electromagnetic radiation to the subcutaneous fat region for at least 300 seconds. A controller is configured to adjust an average power density based on a thickness of skin overlying the subcutaneous fat region, and to cause necrosis of at least one fat cell in the subcutaneous fat region. The non-fat selective wavelength is 950 nm to 1090 nm, 1100 nm to 1160 nm, 1,300 nm to 1625 nm, or 1,800 nm to 2,200 nm.

Abstract: A therapeutic thermal energy measuring system, method and application for a meridian thermal therapy device. The therapeutic thermal energy measuring system for a meridian thermal therapy device comprises: a time setting module for setting a time; a temperature setting module or an intensity level setting module for setting a temperature or an intensity level; a therapeutic thermal energy measuring module for measuring therapeutic thermal energy on the basis of a preset time and a preset temperature or intensity level, and outputting a result, and/or performing real-time measurement of therapeutic thermal energy on the basis of a preset temperature or intensity level and cumulative working hours of a treatment head of the meridian thermal therapy device, and outputting a result. The therapeutic heat energy measuring system can solve a bottleneck problem of having no way of quantizing therapeutic thermal energy in meridian thermal therapy.

Abstract: The present invention relates to a therapy system for the treatment of the skin and subdermis with light. The system comprises a NIR light source which produces light with a wavelength adapted to an absorption maximum for exciting molecular oxygen in aqueous solution; an image recognition unit for detecting papillary end arterioles and their x-y-z coordinates, wherein a respective depth underneath the skin surface is determined as the z-coordinate by an autofocus function; an optical system for the optical coupling of the light of the NIR light source and the pattern recognition unit to the skin, with a focussing unit to controllably position the light with at least one focus point in the skin; and a control unit to control the NIR light source, the image recognition unit, and the optical system.

Abstract: The system comprises: —a bundle of light fibers (11) connected to a light-emitting source (8), and both transmitting light inside the light fiber and emitting light toward a treatment volume (V), —a temperature-modifying system attached to the bundle of light fibers (11) to modify temperature in the treatment volume (V).

Abstract: There is provided a therapeutic apparatus for photodynamic therapy that includes a hollow tube inserted into a living body; an unfolding part that is coupled to one end of the tube and is unfolded; a light irradiation part that is disposed in the unfolding part to irradiate light; and an operating part that is coupled to the other end of the tube to unfold the unfolding part, wherein the light irradiation part irradiates light when the unfolding part is unfolded. The therapeutic apparatus for photodynamic therapy according to the present disclosure allows irradiation of light by unfolding tissues of the curved portion in the living body, using an unfolding part capable of being unfolded depending on the user's selection and the light irradiation part coupled to the unfolding part, there is an effect of allowing the use of the photodynamic therapy even in a portion that cannot be conventionally treated using the photodynamic therapy.

Abstract: The present invention is concerned with a skin treatment device, in particular a hair removal device, having a light emission unit comprising a substrate and a plurality of first LED dies mounted on the substrate on an area of at least 0.2 cm2, in particular of at least 1 cm2, wherein the skin treatment device is arranged to activate the first LED dies to emit a treatment light pulse having a pulse length in particular in the range of between 10 ms and 300 ms and the first LED dies have a radiant flux such that a radiant fluence on the skin of a user of at least 1 J/cm2 is achieved by application of the treatment light pulse, wherein the light emission unit has at least two selectable active areas of first LED dies, where the selectable active areas have different sizes, and at least three second LED dies are mounted on the substrate at locations suitable for visibly indicating each of the selectable active areas.

Abstract: Method, system and computer program product are provided for estimating a circadian phase of a subject by: obtaining a sensed biological signal for the subject; and using, by one or more processors, adaptive frequency tracking to adaptively estimate the circadian phase of the subject from the sensed biological signal. Circadian phase estimation may be accelerated by providing a feedback loop for the adaptive frequency tracking, which utilizes, in part, a circadian phase model in automatically ascertaining a phase correction for the adaptive frequency tracking. The circadian phase estimation may be used in automatically constructing a light-based circadian rhythm model for the subject using a linear parameter-varying (LPV) formulation, and once constructed, the circadian rhythm model for the subject may be used to provide light-based circadian rhythm regulation.

Abstract: The present invention is concerned with a hair removal device having a light emission unit having a substrate and a plurality of first LED dies that are mounted on the substrate on an area of at least 0.2 cm2, in particular of at least 1 cm2, the first LED dies having a peak emission wavelength in the far red or infrared wavelength range of between 700 nm and 980 nm, wherein the hair removal device is arranged to emit a treatment light pulse having a pulse length in the range of between 60 ms and 120 ms and the first LED dies have a radiant flux such that a radiant fluence on the skin of a user in the range of between 3 J/cm2 and 7 J/cm2 is achieved by application of the treatment light pulse.

Abstract: The invention relates to an irradiation apparatus for the prophylaxis of hearing impairment and/or vertigo, to a system of functionally connected apparatus components which interact with each other, and a method that uses the irradiation apparatus for the prophylactic irradiation of the inner ear with photons in order to prevent hearing impairment and/or vertigo in a wearer of the irradiation apparatus.

Abstract: Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in a holdable spot applicator assembly, the holdable spot applicator assembly including a reflective surface facing towards a patient and a plurality of LEDs for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are housed within a holdable elongated structure.

Abstract: Photosensitive cardiac rhythm modulation structures and systems are described. A genetically-engineered tissue comprising a population of pacing cells expressing a photosensitive membrane transport mechanism that is responsive to light of a particular wavelength(s) combined with one or more of a light source, a power generator, and a sensor provides pacemaker and/or defibrillator function to a subject. The systems further provide in vitro model systems for electrophysiological studies.

Abstract: There is provided an organic light emitting display device including a display panel including pixels and a display panel driver configured to drive the display panel. The display panel driver is arranged to receive a maximum brightness signal. When a maximum brightness determined corresponding to the maximum brightness signal is lower than a first reference maximum brightness for a frame, the display panel driver is programmed to direct less than all of the pixels to emit light components during a frame period of the frame. When the maximum brightness is higher than the first reference maximum brightness and is lower than a second reference maximum brightness, the display panel driver is programmed to direct all of the pixels to emit light components during only part of the frame period. The second reference maximum brightness is higher than the first reference maximum brightness.

Abstract: Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization.

Abstract: The invention relates to a light treatment system. The light treatment system comprises a light source for emitting light for illuminating a part of a human or animal body for light treatment. The light treatment system further comprises a housing for emitting light towards the part of the human or animal body, and for at least partially covering the illuminated part of the human or animal body from view. The housing further comprises a window for emitting light from an inner part of the housing away from the housing.

Abstract: A target marking system includes a light source configured to emit a beam of thermal radiation and to impinge the beam onto a target. The system also includes a detector configured to collect radiation passing from the target to the detector along a path. The radiation passing from the target in response to impingement of the beam onto the target. The system further includes an optics assembly disposed optically upstream of the detector along the path. The optics assembly includes at least one of an afocal power changer, a camera objective, a catadioptric lens, and a zoom system configured to condition the radiation passing from the target to the detector.

Abstract: The present invention is concerned with a hair removal device for removal of red hairs that has a light emission unit having a substrate and a plurality of first LED dies emitting at a peak emission wavelength in a wavelength range of between about 480 nm and about 510 nm, the first LED dies being mounted on the substrate on an area in the range of between about 0.2 cm2 and about 100 cm2, wherein the hair removal device is arranged to emit a treatment light pulse by the first LED dies having a pulse length in the range of between about 30 ms and about 200 ms, and the first LED dies have a radiant flux such that a radiant fluence on the skin of a user in the range of between about 3 J/cm2 and about 6 J/cm2 is achieved by application of the treatment light pulse.

Abstract: A light therapy device, including: a housing including a hanging part lying over a user's nose and a bridge part connected to the hanging part; a light source positioned inside the housing and emitting light for treatment; and a rhinitis treatment optical guide having a protruding shape inside the housing to be inserted into the user's nose and guiding the light emitted from the light source to the outside.

Abstract: A novel method to stimulate electrically active biological cells using visible wavelength light and metallic nanoparticles possessing plasmonic properties is presented herein. Using this technology, prosthetic devices such as cochlear and retinal implants and cardiac pacemakers can be developed to have superior properties as compared to the currently utilized electrical stimulation designs. These properties include improved spatial resolution; less or non-invasive devices; and higher fidelity of transduction. An additional advantage of using visible light wavelengths is the avoidance of unwanted heating of surrounding tissue that occurs with infrared stimulation.

Abstract: Light-based systems and methods are provided with targeted antibacterial action for mouth care in animals such as dogs. In various embodiments, the device includes a substantially impermeable shell. The shell has an outer surface. The outer surface has at least one substantially transparent region. The device further includes at least one light-emitting diode disposed within the shell. The at least one light-emitting diode is adapted to emit light having a wavelength between about 400 nm and about 1,000 nm when powered. The at least one light-emitting diode is configured to provide an average light intensity of between about 10 and about 50 mW/cm2 across the at least one substantially transparent region of the outer surface. The device further includes a power source disposed within the shell. The device further includes a switch at least partially disposed within the shell and adapted to control current flow from the power source to the at least one light-emitting diode.

Abstract: A device for delivering light to a nasal cavity is provided. The device has a base at a proximal end of the device. The base has a first end that is the proximal end and a second end opposite the first end. The device also has a sleeve operably connected to the base at the second end, an endpiece connected to the sleeve at a joint, a tapered tip for insertion into the nasal cavity, a light source disposed inside the tapered tip, and a power source to supply power to the device. The endpiece moves in the sleeve during pivoting movement about the joint. The angle between the sleeve and the endpiece is changeable from 0° to 40°.

Abstract: An optical device adapted for a wearer includes an emitting system, a first wafer and a gap. The emitting system includes a halt conducting element configured to output a light through an exit face of the light conducting element towards an eye of the wearer. The first wafer includes an internal face facing the light conducting element. The gap is arranged between at least the exit face of the light conducting element and the wafer. The internal face of the wafer includes at least a curved surface facing the exit face and has a curvature greater than 0 D.

Abstract: The present invention provides various apparatus and methods for improving, augmenting or enhancing a vision of a person that include a first camera, one or more sensors, a microdisplay, and one or more processors communicably coupled to the first camera, the one or more sensors and the microdisplay. The first camera is configured to acquire a first image of a scene facing away from an eye of the person. The microdisplay is configured to display a modified first image to the eye. In one operational mode, the one or more processors are configured to acquire the first image of the scene using the first camera, modify the first image based on one or more vision improvement parameters, and display the modified first image on the microdisplay to improve, augment or enhance the vision of the person.

Abstract: A polish curing assembly for curing and hardening nail polish includes a stand is that may be rolled along a support surface. A light emitting unit is coupled to the stand and the light emitting unit is positionable above a person's hand whose nails have been polished. The light emitting unit emits electromagnetic radiation when the light emitting unit is turned on to cure polish on the nails.

Abstract: An image processing apparatus that can protect user's eyes by reducing harmful blue light in a mode that matches the characteristics of an image to be displayed and the preference of the user who causes the image to be displayed. The image processing apparatus includes a blue light reduction control unit that acquires image information Sin corresponding to an image to be displayed on a display and a pixel value update unit that generates update image information Sbc by reducing at least luminance corresponding to a blue component in the acquired image information Sin so that a reduction rate of the luminance corresponding to the blue component is greater than or equal to reduction rates of luminance corresponding to the other color components in the acquired image information Sin and outputs the update image information Sbc to the display to cause the display to display the update image information Sbc.

Abstract: The present disclosure generally pertains to in vivo drug development and delivery systems and methods. The systems include a hollow tubular assembly with a chamber for receiving and transmitting an ionizing substrate solution, and a structure to transmit non-radioactive ionizing radiation to the ionizing substrate solution. The resulting free radical drug is transferred directly into a patient treatment site through an applicator. The systems and methods described herein provide simple, inexpensive techniques for in vivo production of an optimal chemotherapeutic drug without the use of radioactive radiation and directly injecting the drug into the patient's tissue with very minimal systemic side-effects.

Abstract: Various systems and methods are implemented for in vivo use in a living animal. One such method involves stimulating target cells having light-responsive proteins and includes providing an elongated light-delivery structure in a narrow passageway in the animal, the elongated light-delivery structure having separately-activatable light sources located along the length of the elongated light-delivery structure. The method also includes activating less than all the light sources to deliver light to light-responsive proteins adjacent to the activated light sources along the length of the elongated light-delivery structure, thereby stimulating target cells in vivo.