Abstract: A display control method for controlling display of a display panel, the display control method including: obtaining an image by photographing a viewer; determining whether the viewer is sleepy based on the image; controlling a display mode of the display panel based on whether the viewer is sleepy; and generating an output signal for displaying an image on the display panel based on the display mode, wherein the display panel includes a first blue pixel emitting a first blue light and a second blue pixel emitting a second blue light having a different wavelength from the first blue light, and the display mode is classified based on which of the first and second blue pixels are used.

Abstract: Methods for LED generated low-level light therapy (LLLT) in the red, blue, and IR ranges are described to effectively inhibit fibroblast proliferation in vitro without altering viability, and may be used as therapy for the treatment of scars and other proliferative skin diseases.

Abstract: A method of dynamically adjusting a circadian rhythm comprising the steps of determining a current circadian rhythm status of a circadian rhythm of an observer, accessing a calendar of the observer, and identifying a future event of the observer to precondition for, defined as an identified future event. A preconditioning schedule responsive to the identified future event may then be determined. Furthermore, communication with a light source may be established, and the light source may then be operated to emit light according to the preconditioning schedule.

Abstract: The invention relates to a system for electrical and/or magnetic neuronal stimulation, comprising a signal generator for generating a stimulation signal, in particular an alternating-current stimulation signal, an applicator for applying the stimulation signal, in particular in an area on or directly around the optic nerve, a lead for deriving a measurement signal, in particular an EEG signal, a biomarker calculation unit for calculating a biomarker based on the measurement signal, and an optimization unit, in particular for performing a stochastic optimization process, for optimizing the value of the biomarker by varying the stimulation signal.

Abstract: A method for treating at least one of Grade III capsular contracture and Grade IV capsular contracture in a mammalian subject includes positioning a laser device proximate to the subject. The method also includes applying low level near infrared radiation to an area of the subject proximate to tissue in the subject experiencing at least one of Grade III capsular contracture and Grade IV capsular contracture for treating the capsular contracture.

Abstract: A skin care apparatus suitable for use in proximity to a subject's eyes. The apparatus includes a treatment device and a stimulus device. Upon activation by a user, such as the subject or a technician, a stimulus delivered by the stimulus device causes the subject's eyelid to close prior to the administration of a skin care treatment by the treatment device.

Abstract: A method for treating a subject with low level light therapy for enhancement of neurologic function (e.g., cognitive function) is provided. The method includes noninvasively delivering light energy having a wavelength of about 630 nanometers to about 904 nanometers to the brain of the subject. Delivering the light energy can include (i) irradiating the scalp with light energy having an incident power density less than 1000 mW/cm2 and (ii) transmitting a portion of the light energy through the scalp and the skull to the brain.

Abstract: A method of dynamically adjusting a circadian rhythm comprising the steps of determining a current circadian rhythm status of a circadian rhythm of an observer, accessing a calendar of the observer, and identifying a future event of the observer to precondition for, defined as an identified future event. A preconditioning schedule responsive to the identified future event may then be determined. Furthermore, communication with a light source may be established, and the light source may then be operated to emit light according to the preconditioning schedule.

Abstract: A system and method for using a virtual reality or an augmented reality environment for the measurement and/or improvement of human vestibulo-ocular performance can be implemented by combining a video camera based eye orientation sensor, a head orientation sensor, a display, and an electronic circuit that connects the eye sensor, head sensor, and display. The system and method can be operated in the range of frequencies between 0.01 Hertz and 15 Hertz. The system and method can use a Fourier transform to compute a gain and a phase. The system and method can be used for measuring vestibulo-ocular reflex, dynamic visual acuity, dynamic visual stability, kinetic visual acuity, retinal image stability, or foveal fixation stability in a non-clinical setting. The system and method can be completely portable, head-worn, and self-contained.

Abstract: Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in an assembly comprising a first wall to which the lamps are affixed thereto and a second wall, closer to the patient, spaced from the first wall wherein the lamps are recessed relative thereto. The second wall comprises a reflective surface facing towards a patient and a plurality of light apertures substantially aligned with the LEDs on the first wall for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are disposed between the first and second wall so that the reflective surface is relatively smooth and seamless towards the patient. The walls may include an eye slot. The device is mounted to the user with a frame comprising an eyeglass frame or goggles including lenses for shielding the user's eyes from lamp radiation.

Abstract: It is intended to provide a therapeutic and/or diagnostic agent that can be used in photodynamic therapy (PDT) or photodynamic diagnosis (PDD) capable of utilizing infrared-spectrum light such as near-infrared light (NIR), infrared light, or far-infrared light, which attains a deep body penetration. The present invention provides a photodynamic therapeutic or diagnostic agent or a photodynamic therapeutic or diagnostic kit for cancer or infectious disease, comprising: a particle (e.g., a lanthanide particle) that emits upconversion luminescence by infrared-spectrum light such as near-infrared light having a wavelength of 0.7 ?m to 2.5 ?m; and a photosensitizer (e.g., porphyrin) or a 5-aminolevulinic acid group.

Abstract: Phototherapy systems comprising a therapeutic lamp platform for radiant lamps such as LEDs disposed in an assembly including a reflective surface facing towards a patient and a plurality of light apertures substantially aligned with the LEDs for communicating lamp radiation from the lamps to a user. The lamps and associated circuitry are disposed so that the reflective surface is relatively smooth and seamless towards the patient. The walls have a malleable rigidity for flexible adjustability relative to the user, and the device is mounted to the user with a frame.

Abstract: An illumination distribution system for distributing high power illumination to a set of projectors. The system includes a display element, such as a spatial light modulator (SLM), receiving light from a laser. The system includes a fiber optic array with connection locations for optical fibers. The system includes projectors that are each coupled to the fiber optic array at one or more of the connection locations with at least one optical fiber. The system includes a controller operating the display element at a first time to display a first hologram and at a second time to display a second hologram differing from the first hologram such that the laser light is split, with equal or unequal splitting ratios, into beams that are selectively directed to the connection locations of the fiber optic array (e.g., based on a 2D routing pattern used to generate the holograms).

Abstract: In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein.

Abstract: The device intended for the stimulation of the brain by laser circularly or elliptically polarized light consists of the main unit (1) equipped in the front part with control buttons (3), and a display (2) from which at least one laser diode (16, 17, 18, 19) is supplied. At least one nasal applicator (8, 9, 10, 11) or nasal applicators (38, 39) suitably equipped in the rear part with laser diodes (40, 41) can be connected to the upper part of the main unit (1). The main unit (1) is supplied in its lower part through a connector (33), and the programmable control unit (51) with built-in battery (56) and autonomous processor (57) is an integral part of the device.

Abstract: Light therapy is provided to a subject through a sleep mask. The sleep mask is configured to deliver electromagnetic radiation to the closed eyelids of the subject within a defined optimal wavelength band that is therapeutically impactful in modulating circadian and related systems of the subject.

Abstract: A method for controlling activation of Riboflavin applied to an eye includes applying the Riboflavin to a selected region of a cornea of the eye and initiating cross-linking activity in the selected region by activating the Riboflavin with pulsed light illumination. The pulsed light illumination has an irradiance, dose, and an on/off duty cycle. The irradiance, the dose, and the on/off duty cycle are adjusted in response to a determination of photochemical kinetic pathways for Riboflavin cross-linking activity and to control photochemical efficiency.

Abstract: An apparatus and method is provided for skin treatment. The apparatus includes an applicator assembly that includes an applicator tip which is configured to apply a normal cyclical mechanical force to a skin surface area of a user and to deliver a skin formulation to a skin surface area of a user. The apparatus further includes an electromagnetic energy assembly that includes at least one electromagnetic energy source adjacent to or within the applicator assembly and configured to deliver a continuous electromagnetic energy stimulus of a character and for a duration sufficient to penetrate one or more dermal layers within the skin surface area of a user.

Abstract: A light emitting device for use as a hair removal device is provided. The light emitting device has at least one radiation source for electromagnetic radiation providing at least one operating beam during operation of the device, a housing being intransparent for the operating beam having an output opening, at least one radiation source for electromagnetic radiation providing at least one sensing beam during operation of the device, at least one detector for detecting the sensing beam, at least one sensing window having a contact boundary surface, and a controller communicating with the radiation source providing the operating beam and with a detector and being operable to influence operation of the radiation source providing the operating beam responsive to the sensing beam detected at the detector.

Abstract: A neural network is disclosed. The neural network comprises a plurality of optogenetically modified neural cells being three-dimensionally distributed in a hydrogel medium and being disconnected from any solid support having a shear modulus above 1 GPa.

Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.

Abstract: Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.

Abstract: A lighting system for initiating change in a mammal's circadian or well-being state includes a computational unit configured to receive state information regarding the mammal's circadian or well-being state, and operational information from a light sensor with spectral and luminosity sensitivity. The computational unit is configured to compare the operational information with the state information, and on the basis of this comparison, the computational unit outputs a control signal to a light control unit which, in turn, adjusts a controllable light source to vary its light output so as to initiate the desired change in the mammal's circadian or well-being state.

Abstract: The present disclosure provides a method of inducing or modulating reward- or aversive-related behaviors in animals using light-responsive opsins. The present disclosure provides methods of identifying or screening compounds that may be used to treating mental disorders, or are relevant to disrupt or improve reward- or aversive related behaviors.

Abstract: The invention relates to a hair-shortening device. The device is based on the principle of laser-induced optical breakdown, wherein a laser pulse causes mechanical effects in tissue, which are used to cut the hair (20). The invention uses the insight that, when two or more such laser pulses are provided simultaneously, the mechanical effects can co-operate. This in turn allows cutting of the hair (20) with less total energy, down to about half the energy required for cases with pulses that are supplied sequentially. In one embodiment, the device comprises a laser source (2), a grating (6), and a beam manipulator (8), that aim a plurality of simultaneous focal spots (10) into a hair (20).

Abstract: A disinfection device includes a radiation lamp (112) having an aperture for delivering radiation. A flexible shroud (132) surrounds a perimeter of the aperture. The shroud includes a surface configured to deform and create a seal around the aperture when in contact with a target surface. A sensing circuit (120, 156) is configured to sense a state of the seal and enable the radiation lamp when the seal is complete.

Abstract: An LED lighting system having at least one LED circuit and at least two circuits or drivers capable of receiving an AC voltage at a first frequency and having an output capable of driving the at least one LED circuit, wherein the output of each circuit or driver capable of driving the at least one LED circuit is provided to the at least one LED circuit through a circuit or sensor capable of permitting only a single output from the at least two circuits or drivers be provided to the at least one LED circuit.

Abstract: Described is a dermal system which contains at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal system can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient. The at least one light source is a thin light source comprising at least one inorganic light emitting diode (LEDs) and/or at least one organic light emitting device.

Abstract: The control device for controlling a therapy light source including an input for receiving information on an intensity and/or amount of light a person has been exposed to from a wearable device that can connect to the control device via the input. The control device further includes an output for controlling at least one therapy light source that can be connected to the control device. A control unit of the control device is designed to control a connected therapy light source dependent on the information on the intensity and/or amount of light the person has been exposed to. A wearable device that is suited to operate in combination with the control device includes a light sensor for detecting an intensity of received light. It further comprises a storage unit connected to the light sensor for storing at least one value related to the measured intensity of the received light.

Abstract: This application is directed to a method of treating onychomycosis by applying a phototherapeutic agent to a nail structure, waiting for a period of at least three days, and exposing the nail to light that causes an activation reaction. The phototherapeutic agent may be amino levulinic acid, alkylated derivatives of ALA, and their pharmaceutically acceptable salts.

Abstract: Disclosed herein are optical assemblies having thin, low profile shapes. These optical assemblies may be used with fiber coupled lasers and other light sources, including high power sources, to irradiate tissue at a wavelength suitable for inducing ablation or coagulation to a target depth, denaturation, thermal modification of a tissue, and/or preferential injury to a target tissue structure. Example optical assemblies can produce substantially uniform illumination patterns that are useful for treating superficial tissue, including the internal or luminal (e.g., esophageal) tissue. Some examples may have capability for cooling superficial tissue or skin, such as a detachable, reusable heat sink for active cooling without consumables, fluid pumps, or other cooling equipment.

Abstract: A light therapy device (1) comprises: at least one light source (2); a control device (10) for controlling the operation of the light source; a boundary memory (11) containing boundary information defining boundaries for the distance (D) and relative angle (f) of a user's head with respect to the light source; monitoring means (30) for monitoring the actual distance and actual relative angle of the user's head and generating an output signal indicating the measured distance and angle. The control device has an input coupled to the memory for receiving the boundary information, and has an input coupled to the monitoring means for receiving the output signal from the monitoring means. The control device compares the output signal from the monitoring means with the boundary information, and issues a warning signal when the actual position and/or orientation of the user's head and/or eyes is/are outside said boundaries.

Abstract: Methods and apparatus for irradiating biological tissue by EM radiation having radiation frequency(ies) of at most 10 Gigahertz are disclosed herein. In some embodiments, the tissue is irradiated by passing converging EM waves (e.g. generated using an ellipsoidal mirror 110) through a surrogate medium having a specially shaped ENTRY_SURFACE via which the converging EM waves enter the surrogate medium. In some embodiments, a refractive index at a sub-10 Gigahertz of the surrogate medium is at least 2 or at least 3 or at least 5 and/or substantially matches a refractive index of an irradiated biological tissue. In some embodiments, converging EM waves are formed within the surrogate medium. Some embodiments relate to methods and apparatus for irradiating neuron(s), for example, to non-invasively stimulating or otherwise modify a behavior of neuron(s) using focused or non-focused EM radiation.

Abstract: A fat reducing device and method utilizing optical emitters includes an array housing a plurality of optical emitters which are positioned to produce an optical output directed to a recipient, and a controller for instructing an operation of the array. The optical output being generated by a plurality of LED's cumulatively producing red light at approximately 635 nm, and at approximately 40,000 Lux, measurable at the array. The method includes reducing the lipid content of subcutaneous adipocytes using the optical emitting device, by delivering red light at approximately 313.6 Lux at a wavelength of approximately 635 nm for between 1 and 8 minutes, resulting in a total delivery of 2.88 Joules to the subcutaneous adipocytes of the target area of the recipient.

Abstract: The present invention relates to a cells and cell tissue treatment device and use thereof.

Abstract: Embodiments of the technology described herein relate, at least in part, to methods of modulating the activity of a neuron by contacting the neuron with a photo-sensitive TrpA1 agonist and then illuminating the neuron with electromagnetic radiation. Also described herein are photo-sensitive TrpA1 agonists.

Abstract: A method for imaging the erosion of a biomaterial is disclosed. More specifically, the present invention provides a method for imaging a labeled biomaterial so that the erosion of the biomaterial is measured in vivo over a period of time. A biomaterial such as, for example, a hydrogel including polyethylene glycol (PEG) is labeled with a fluorescent or bioluminescent marker. The labeled biomaterial is then employed in the construction of an implanted medical device such as, for example, an endovascular stent. Furthermore, the labeled biomaterial may be utilized to form a drug delivery system that releases a controlled amount of a drug into a local region within a patient. The erosion of the biomaterial is monitored through a noninvasive imaging method.

Abstract: A display device and driving method of a backlight module are disclosed. The display device includes a display panel and a backlight module. The backlight module includes a first light source, a second light source and a control module. The first light source emits a first spectrum with a first stimulus and the second light source emits a second spectrum with a second stimulus. The second stimulus is substantially bigger than the first stimulus. The control module enables the second light source during a first period and enables the first light source during a second period.

Abstract: The present invention relates to a method and device for illuminating and at the same time purifying or disinfecting products such as air, flowers, food, vegetables, meat, poultry or fish. The method comprises the use of IR emitting LED elements.

Abstract: An opto-electric device includes an opto-electric layer structure having an anode and a cathode layer and an opto-electric layer arranged between the anode and cathode layers, and having a light-transmission side. A dual electrically conductive layer structure is arranged at a side of the opto-electric layer structure opposite the light-transmission side, the dual electrically conductive layer structure having a first and a second electrically conductive layer mutually insulated by a first electrically insulating layer. A second electrically insulating layer is arranged between the light emitting layer structure and the dual electrically conductive layer structure, wherein the first electrically conductive layer is electrically connected by at least a first transverse electrical conductor with the anode layer and the second electrically conductive layer is electrically connected by at least a second transverse electrical conductor with the cathode layer.

Abstract: This invention discloses methods and apparatus for providing an ophthalmic lens with light source capable of providing specific bandwidths of light to an eye of a wearer. In some embodiments, an ophthalmic lens is cast molded from a silicone hydrogel and an energy source and light source encapsulated within the ophthalmic lens.

Abstract: A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.

Abstract: A photoacoustic imaging apparatus includes holding members configured to hold a subject, an acoustic wave conversion unit configured to receive an acoustic wave generated by irradiating the subject, which is held by the holding members, with light from a light source and convert the acoustic wave into an electric signal, a processing unit configured to generate image data from the electric signal, and an imaging unit configured to capture an optical pattern generated on a light diffusion member by emitting the light to the light diffusion member arranged on a surface of a side where the subject is irradiated with the light in the holding members where the holding members contact the subject in holding the subject, wherein the processing unit calculates light absorption coefficient distribution in the subject based on the optical pattern captured by the imaging unit and the electric signal acquired by the acoustic wave conversion unit.

Abstract: Solutions for limiting the undesirable spread of pathogens by indirect contact are provided. The solutions involve heat-sanitization of contact regions on articles or fixtures by flowing selected electromagnetic radiation energy through underlying waveguide structures substantially parallel to the contact regions.

Abstract: The invention relates to a light treatment system (10, 12). The light treatment system comprises a light source (20, 22) for emitting light (100) for illuminating a part of a human or animal body (30) for light treatment. The light treatment system further comprises a housing (40, 42) for emitting light towards the part of the human or animal body, and for at least partially covering the illuminated part of the human or animal body from view. The housing further comprises a window (50, 52, 54, 56) for emitting light from an inner part of the housing away from the housing. An effect of the light treatment system according to the invention is that the window in the housing may be used as indicator whether the light treatment system is operating and/or functioning well. Furthermore, the presence of a luminescent material, for example, on the window, may be used as indicator for, for example, ultraviolet light as part of the ultraviolet light may be converted by the luminescent material into visible light.

Abstract: The present invention relates to a otitis media diagnosis system using terahertz electromagnetic waves, which can diagnose otitis media using terahertz electromagnetic waves in a non-invasive manner, and which can accurately diagnose otitis media by acquiring images on the tympanic cavity using terahertz electromagnetic waves with excellent transmittance, and which can quickly and accurately divide exudative otitis media and suppurative otitis media using terahertz electromagnetic waves that are sensitive to moisture, and which is safe to a body using terahertz electromagnetic waves. The otitis media diagnosis system includes a terahertz probe including a generating unit for radiating terahertz electromagnetic waves from the outside of an ear toward a tympanic cavity and a detection unit for detecting the reflected terahertz electromagnetic waves reflected from the tympanic cavity.

Abstract: A sleep mask is configured to provide light therapy to a subject. The sleep mask may provide a comfortable delivery mechanism for the light therapy, and may deliver the light therapy to the subject while the subject is asleep, in the process of going to sleep, and/or waking from sleep. In one embodiment, the sleep mask includes one or more of a shield, a strap, a first lighting module, and/or a second lighting module.

Abstract: A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects related to exposing to a light output a skin portion including a condition treatable in whole or in part with light. In one exemplary embodiment for skin treatment including tattoo removal, perfluorodecalin is used to inhibit or resolve whitening, for example to speed a laser therapy session.

Abstract: Methods for the treatment of a cell proliferation disorder in a subject, involving: (1) administering to the subject at least one activatable pharmaceutical agent that is capable of effecting a predetermined cellular change when activated, either alone or in combination with at least one energy modulation agent; and (2) applying an initiation energy from an initiation energy source to the subject, wherein the applying activates the activatable agent in situ, thus causing the predetermined cellular change to occur, wherein the predetermined cellular change treats the cell proliferation disorder, preferably by causing an increase or decrease in rate of cell proliferation, and a kit for performing the method, a computer implemented system for performing the method, a pharmaceutical composition useful in the method and a method for causing an autovaccine effect in a subject using the method.

Abstract: A spectral color and light therapy system is described which is useful in treating mood, anxiety, attention, substance, and/or behavioral disorders. The system utilizes one or more light source which emits visible colored light at a brilliance factor of at least about 2500 and at least one of four colors which are different from each other, said system providing (a) (i) a light source emitting blue light in the range of about 450 to about 475 nm; and (ii) a source emitting green visible light in the range of about 495 nm to about 570 nm; and (b) a light source emitting rose pink light in the range of about 635 nm to about 650 nm; and a light source of peach light in the range of about 590 nm to about 630 nm. Also provided are methods of treating mood, anxiety, attention, substance, and/or behavioral disorders. Methods of treating and/or ameliorating the symptoms of autism spectrum disorders are described.