Abstract: A method and apparatus are provided for estimating the location of a portable device. The method includes providing a plurality of location anchor and enhanced location anchor transceivers within a region, each operating from respective predetermined locations, a portable transceiver measuring a signal parameter from the transceivers, a location engine determining a location of the portable transceiver based upon the signal measurements and the respective predetermined locations of the transceivers, each of the enhanced transceivers measuring a signal parameter from some of the location and other enhanced transceivers, the location engine calculating an estimated location for each of the plurality of enhanced transceivers and calculating a location error based upon the estimated location and predetermined location of the enhanced location anchor transceiver.

Abstract: Nuclear quadrupole resonance measurement using two or more wire loop(s) within a space to define a portal, and driving the wire loop(s) with a baseband digital transmitter generating a chirped or stepped signal, to create a corresponding varying electromagnetic field within the portal. Coherent emissions reflected thereby are detected through a directional coupler feeding the transceiver. The detected coherent emissions are processed with a matched filter to determine presence of a target object within the portal.

Abstract: Techniques for sensing chemicals in aqueous environments, and systems configured for sensing chemicals in aqueous environments are provided. More particularly, techniques and systems for detecting a presence or absence of aromatic chemicals in aqueous environments are provided. An example may include receiving emitted light from a first port of an optical circulator, reflecting at least a portion of the received emitted light to produce reflected light, and transmitting the reflected light from the second port of the optical circulator. The reflected light may be produced, at least in part, by an interaction of chemicals and an array of photonic silica of the second port.

Abstract: LC/MS data generated by an LC/MS system is analyzed to determine groupings of ions associated with originating molecules. Ions are grouped initially according to retention time, for example, using retention time or chromatographic peaks in mass chromatograms. After initial groupings are determined based on retention time, ion peak shapes are compared to determine whether ions should be excluded. Ions having peak shapes not matching other ions, or alternatively a reference peak shape, are excluded from the group.

Abstract: Disclosed is a flow meter and method for measuring water cut and salinity of a multiphase mixture. The water-cut meter includes a conduit configured to receive the multiphase mixture, and a probe array configured to measure a cross-sectional area of the conduit. The probe array includes a plurality of coaxial probes connected in parallel. Optionally, the probe array is configured to operate at a single high frequency, for example, 1 to 3 GHz, to minimize conductivity loss relative to capacitance. The flow meter further includes a processor configured to transmit a signal to the probe array and to receive a reflected signal from the probe array using a single channel. The processor is further configured to calculate the water cut and the salinity of the multiphase mixture based on a single complex permittivity of the multiphase mixture calculated from the received reflected signal.

Abstract: The current invention concerns a method for identifying the elemental composition of and/or quantifying the presence of mono-isotopic elements in a molecule in a sample by computing a solution of a system of linear equations ??Ei?n?=Fi, whereby the set of numbers Fi comprises said set of relative peak heights from the aggregated isotopic distribution and the coefficients Ei? of said linear system comprise powers and/or power sums of roots r?,i?. The present invention also provides a method for analysing at least part of an isotopic distribution of a sample, comprising obtaining data comprising at least one probability qj with which a j'th aggregated isotopic variant of said molecule with mass number Aj occurs within said aggregated isotopic distribution; and computing a probability qi with which an i'th aggregated isotopic variant occurs within said aggregated isotopic distribution, by taking a linear combination of said at least one probability qj.

Abstract: A system and method to obtain correct gas density and flux measurements using (i) gas analyzer (open-path, or closed-path gas analyzers with short intake tube, or any combination of the two); (ii) fast temperature or sensible heat flux measurement device (such as, fine-wire thermocouple, sonic anemometer, or any other device providing fast accurate gas temperature measurements); (iii) fast air water content or latent heat flux measurement device (such as, hygrometer, NDIR analyzer, any other device providing fast accurate gas water content measurements); (iv) vertical wind or sampling device (such as sonic anemometer, scintillometer, or fast solenoid valve, etc.) and (v) algorithms in accordance with the present invention to compute the corrected gas flux, compensated for T-P effects. In case when water factor in T-P effects is negligible, the fast air water content or latent heat flux measurement device (item iii in last paragraph) can be excluded.

Abstract: The present invention relates to a method of detecting soil nutrients or soil nutrients in soil from reflected light, and also includes systems for the measurement, calculation and transmission of data relating to or carrying out that method.

Abstract: Data for a plurality of samples collected by an LC/MS, GC/MS or other systems are converted into a two-dimensional table format without losing information and with a light load, thereby allowing a multivariate analysis processing to be efficiently performed. After LC/MS data on a plurality of samples are obtained and the respective extracted ion chromatograms (XICs) are created (S1 and S2), the correction of the retention-time difference, the waveform processing and the like are performed (S3 and S4), followed by the creation of a one-dimensional table in which the signal-strength values are arranged for each XIC. Then, one-dimensional tables of a plurality of XICs for one sample are joined together in order of m/z value to create an elongate one-dimensional table (S5). The elongate one-dimensional tables of a plurality of samples are arranged in another dimensional direction to obtain a two-dimensional table (S6).

Abstract: The present invention accepts attribute information of evaluation subject parts, and judgment standards of parts category by a data acquiring unit; acquires attribute information and chemical substance information relating to a part already inspected; categorizes the relevant attribute information and the relevant chemical substance information to a part group having attribute information of the evaluation subject parts, and a part group not having it; carries out calculation of statistic values of the content rate of a specified chemical substance in each of the parts groups, comparison between difference of said statistic values in each of the parts groups and the relevant judgment standards, and extraction of said attribute information; extracts attribute information and chemical substance information of said parts already inspected, coincident with all of attribute information extracted; and calculates the statistic value such as an average value relating to the content rate of the chemical substance of t

Abstract: An initial concentration of the residual concentration of a causative substance contained in an insulating oil is compared with a reference value. The causative substance reacts with a conductor forming a winding of an oil-filled electrical device to generate an electrically conductive compound. The reference value is defined as a value for determining whether a main determinant that determines the lifetime of the oil-filled electrical device is generation of the electrically conductive compound or degradation of insulating paper. Based on the initial concentration of the causative substance and the reference value, the lifetime of the oil-filled electrical device is assessed.

Abstract: A product ion spectrum is created on the basis of MS2 analysis data respectively obtained for a parent compound and a metabolite (S1 and S2). Additionally, a neutral loss spectrum, in which the mass of each product ion is replaced with a mass difference between the mass of the product ion and that of a precursor ion, is created (S3). Then, a common peak having the same mass in both the parent compound and the metabolite is extracted (S4), and a complementary peak appearing at a position corresponding to the difference between the mass of the common peak and that of the precursor ion is extracted (S5); the complementary peak corresponding to a common peak located on the product ion spectrum appears on the neutral loss spectrum, while the complementary peak corresponding to a common peak located on the neutral loss spectrum appears on the product ion spectrum.

Abstract: A method for analysis, control, and manipulation for improvement of the chemical reaction rate of a protein-mediated reaction is provided. Enzymes, which typically comprise protein molecules, are very efficient catalysts that enhance chemical reaction rates by many orders of magnitude. Enzymes are widely used for a number of functions in chemical, biochemical, pharmaceutical, and other purposes. The method identifies key protein vibration modes that control the chemical reaction rate of the protein-mediated reaction, providing identification of the factors that enable the enzymes to achieve the high rate of reaction enhancement. By controlling these factors, the function of enzymes may be modulated, i.e., the activity can either be increased for faster enzyme reaction or it can be decreased when a slower enzyme is desired.

Abstract: Methods, computer systems, and computer program products for antibody engineering. A variant set for an antibody of interest is constructed by identifying, using a plurality of rules, a plurality of positions in the antibody of interest and, for each respective position in the plurality of positions, substitutions for the respective position. The plurality of positions and the substitutions for each respective position in the plurality of position collectively define an antibody sequence space. A variant set comprising a plurality of variants of the antibody is selected. A property of all or a portion of the variants in the variant set is measured. A sequence-activity relationship is modeled between (i) one or more substitutions at one or more positions of the antibody of interest represented by the variant set and (ii) the property measured for all or the portion of the variants in the variant set.

Abstract: Specific-site extraction unit 24 extracts specific sites from microscopy images that are obtained by staining or fluorescence labeling of specific sites in a specimen 4, Based on the similarity between MS imaging data and the spatial distribution of the specific sites, cluster analysis unit 25 and division count determination processing unit 26 evaluate the similarity with the spatial distribution of all pixels that belong to one cluster when each of the pixels are categorized into a plurality of clusters. Since the specific sites are sites that include the same characteristic substance, clustering is judged to be appropriate if the similarity in spatial distribution is high. Hence, based on the correlation between spatial distributions, an appropriate division count for the cluster analysis is determined, and the result of the cluster analysis using the division count is output on a display unit 31.

Abstract: Described are techniques for processing data. Sample analysis is performed generating scans of data. Each scan comprises a set of data elements each associating an ion intensity count with a plurality of dimensions including a retention time dimension and a mass to charge ratio dimension. The scans are analyzed to identify one or more ion peaks. Analyzing includes filtering a first plurality of the scans producing a first plurality of filtered output scans. The filtering including first filtering producing a first filtering output, wherein the first filtering includes executing a plurality of threads in parallel which apply a first filter to the first plurality of scans to produce the first filtering output. Each of the plurality of threads computes at least one filtered output point for at least one corresponding input point included in the plurality of scans. Analyzing includes detecting one or more peaks using the filtered output scans.

Abstract: The present invention is directed to a method for automatic selection of colorants and flakes to produce one or more matching formulas to match color and appearance of a target coating containing flakes. The present invention is further directed to a system for automatic selection of colorants and flakes for producing one or more matching formulas to match color and appearance of a target coating.

Abstract: A method, computer program and system to identify peaks generated by different physical ions in a solution including substances by analyzing mass and intensity coordinates of all peaks in a set of mass spectra measured with errors for a certain concentration c of the solution is here disclosed. The peaks in different mass spectra are associated to a same ion if they are sufficiently ‘close’ according to specific discrimination criteria that go beyond the proximity of mass values. A two stage process is applied, each stage consisting in applying the method to identify peaks in mass spectra. In stage 1, the method to identify peaks is applied on each set of mass spectra for each concentration. Resulting sequences of peaks, one peak in each spectrum, are associated to different ions. This output of stage 1 is converted into a set of virtual mass spectra having as virtual peaks, average peak coordinate values calculated on each sequence.

Abstract: This invention pertains to methods and means for measuring substances and for ascertaining and/or computing data pertaining to measured substances. Various embodiments of the methods and means of the invention may be performed by and/or implemented in hardware, in software, by one or more entities, and/or by some combination of hardware, software and/or one or more entities.

Abstract: Described herein are methods that may be used related to mass spectrometry, such as mass spectrometry analysis, mass spectrometry calibration, identification of proteins/peptides by mass spectrometry and/or mass spectrometry data collection strategies. In one embodiment, the subject matter discloses a phase-modeling analysis method for identification of proteins or peptides by mass spectrometry.

Abstract: This present invention is that of an accurate and immediate methodology of carbon monoxide detection is accomplished by utilizing an inserted modified venturi that samples air flow exiting in the immediate vicinity of a heater source's duct system. This is completely functional in any type of heating system incorporating a duct system for forced hot air transfer throughout a circuitous closed environment. Further, upon detection of any carbon monoxide in said heating system, at the immediate source of heated air exiting, an annunciation alarm and heating system “shut down” or “fail-safe” mode will be instituted in effect. All monitoring will be under constant control by algorithms within a microcontroller circuit.

Abstract: The present invention provides various biomarkers of depression. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of depression, methods of determining predisposition to depression, methods of monitoring progression/regression of depression, methods of assessing efficacy of compositions for treating depression, methods of screening compositions for activity in modulating biomarkers of depression, methods of treating depression, as well as other methods based on biomarkers of depression.

Abstract: The systems and methods described herein provide a scientific and analytical basis for the following: (a) collective interpretation of the entire spectrum of chromatographic data, e.g., GC×GC two-dimensional data, with capability of operating at multi-resolution over bigger or smaller sub-regions of the two-dimensional data, (b) given two or more samples that are from the same source, and some samples from clearly different sources, quantitatively estimate where the fingerprint of the source lies, (c) given a source signature template, an unknown sample can be compared to decide whether it is related to, and if so, to what degree, to this source, and (d) given two source signature templates, the templates can be compared to determine how related is one source to the other.

Abstract: The inventors have discovered a collection of proteinaceous biomarkers (“AD biomarkers) which can be measured in peripheral biological fluid samples to aid in the diagnosis of neurodegenerative disorders, particularly Alzheimer's disease and mild cognitive impairment (MCI). The invention further provides methods of identifying candidate agents for the treatment of Alzheimer's disease by testing prospective agents for activity in modulating AD biomarker levels.

Abstract: According to one embodiment of the present invention, an electrochemical sensor (10) for detecting the concentration of analyte in a fluid test sample is disclosed. The sensor (10) includes a counter electrode having a high-resistance portion for use in detecting whether a predetermined amount of sample has been received by the test sensor.

Abstract: A method of calibrating an ion trap having electrodes to which main RF trapping and resonant ejection voltages are applied comprises: identifying, for each of a plurality of ion types having different respective mass-to-charge ratios, an optimum resonant ejection voltage amplitude at which a mass peak quality is optimized when the ion trap mass analyzer is operated at a selected scan rate; determining a best-fit function of the form Vreseject=mc(a+bm), where Vreseject and m represent resonant ejection voltage amplitude and mass-to-charge ratio and a, b and c are constants; identifying, for each of a plurality of ion types, a respective RF voltage amplitude at which ions of each respective type are ejected from the ion trap using a resonant ejection voltage calculated according to the best-fit function; and determining a second best-fit function relating the identified trapping voltage amplitudes to mass-to-charge; ratio.

Abstract: There is provided a system for supporting the assessment as to which disease group the subject to be examined falls in or what position in the whole disease group the subject is in. This support system comprises the data storage part which stores feature values of optical bio-measurement data of many subjects including patients in multiple disease groups, the analysis part which extracts plural kinds of feature values from the optical bio-measurement data and the display part which displays the results of analysis in the analysis part associated with the dictionary data, wherein the display part produces a scatter diagram on which features values of the dictionary data are plotted, with one of the two feature values being plotted along the axis of abscissa and the other along the axis of ordinate, and displays the positions of the subject to be assessed on the scatter diagram superimposed on the scatter diagram.

Abstract: Technologies for increasing sample throughput by predicting the end point response time of a sensor for the analysis of an analyte in a sample are disclosed. In one aspect, a system includes a sensor that generates data signals associated with the measurement of an analyte within the sample. A processor records appropriate data points corresponding to the signals, converts them to a logarithmic function of time scale, and plots the converted data points. The processor then determines a curve that fits the plotted data points and determines a curve fitting equation for the curve. Once the equation is determined, the processor extrapolates an end point response of the sensor using the equation. A value, such as analyte concentration, is then calculated using the extrapolated end point response.

Abstract: A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.

Abstract: A computer-readable, non-transitory medium stores therein a design support program that causes a computer capable of accessing a storage device storing therein for each cell, an output voltage value of the cell, for each elapsed time period from a start of variation of an input voltage applied to the cell, to execute a process. The process includes extracting from the storage device, the output voltage value for each elapsed time period related to an cell under design selected from circuit information of a circuit under design; determining based on a specific voltage value, an extracted elapsed time period to be corrected; adding a time constant of an output from the cell under design to the elapsed time period determined to correction; and outputting the output voltage value for each corrected elapsed time period and the output voltage value for each elapsed time period that is not determined for correction.

Abstract: A method for the calibration of a device for measuring the total organic carbon content (TOC) of an aqueous solution by measuring resistivity. The method includes the following steps, in the presence of a reference TOC analyzer: (a) producing a calibration point by a measurement carried out on ultrapure water by the device and the analyzer; (b) producing a plurality of calibration points, each calibration point corresponding to a measurement of the resistivity of a solution having a given content of photo-oxidizable compound, by the device and the analyzer, in order to establish a correlation between the values measured by the device and the analyzer; and (c) calibrating the device by at least one algorithm, based on the measurements carried out in the previous step.

Abstract: Systems and methods are used to predict intensities of a saturated peak using a peak predictor. A set of data is selected from the plurality of intensity measurements that includes a saturated peak. Confidence values are assigned to each data point in the set of data producing a plurality of confidence value weighted data points. A peak predictor is selected. The peak predictor is applied to the plurality of confidence value weighted data points of the saturated peak producing predicted intensities for the saturated peak. The confidence values can include system confidence values, predictor confidence values, or a combination of system confidence values and predictor confidence values. The peak predictor can be a theoretical model, a dynamic model, an artificial neural network, or an analytical function representing a best fit of a plurality of probability density functions to a first set of measured data that includes a representative non-saturated peak.

Abstract: A measuring system for precise measuring a density of a medium flowing in a pipe line. The measuring system comprises a temperature sensor and a pressure sensor. Both sensors communicate with a measuring electronics of the system. The measuring electronics are operable to provide, based on temperature measurement and pressure measurement, a provisional density measured value, especially according to one of the industrial standards AGAR, AGN NX-19, SGERG-88 IAWPS-IF97, ISO 12213:2006. Further, the measuring electronics provides, based on the provisional density measured value and a density correction value, which is dependant on a flow velocity of the medium, and temperature measurement, a density measured value, which differs from the provisional density measured value, and which represents the density to be measured more accurately.

Abstract: A method of characterizing an object includes determining a depth-wise composition of the object at a measurement site within the object. A property of the object within a region adjacent to the measurement site can, optionally, be estimated based on the determining. Another method of characterizing an object includes disposing at least a portion of an object within a measurement region of a metrology tool, aligning a feature of the object and a location of a designated measurement site within the measurement region relative to each other, and performing a performing a compositional analysis of a portion of the object occupying the measurement site. Various apparatus for performing these methods are also disclosed, as are methods of monitoring manufacturing processes based on these methods.

Abstract: Data representative of a measured carbon dioxide (CO2) concentration and of a measured oxygen (O2) concentration at a measurement location can be used to determine whether the measured carbon dioxide concentration at the measurement location is elevated relative to a baseline carbon dioxide concentration due to escape of carbon dioxide from a source associated with a carbon capture and storage process. Optionally, the data can be used to quantify a carbon dioxide concentration increase at the first location that is attributable to escape of carbon dioxide from the source and to calculate a rate of escape of carbon dioxide from the source by executing a model of gas-phase transport using at least the first carbon dioxide concentration increase. Related systems, methods, and articles of manufacture are also described.

Abstract: Embodiments herein provide detection of contamination at one or more contacts of a sensor system. The sensor system includes a sensor assembly and an electronics assembly communicatively coupled together by one or more contacts. The sensor assembly passes a sensor signal to the electronics assembly for further processing. The electronics assembly includes a detection contact for detecting contamination on or near one or more contacts of the sensor assembly and/or the electronics assembly. A switch selectively couples the detection contact to a bias voltage during a measurement mode and to a reference voltage during a detection mode, the reference voltage being different from the bias voltage. A method of contamination detection includes switching the electronics assembly between the measurement mode and the detection mode, and monitoring for a change in the output signal received by the electronics assembly.

Abstract: In operating a gas turbine, there can be a difference between the desired heating value of the fuel and the actual needs of the fuel for the supplied fuel to be ignited. In one aspect, fuel parameters related to the molecular weight of the fuel such as specific gravity and pressure drop are determined. Ignitability of the fuel is calculated based on the fuel parameters and adjusted as necessary to bring the fuel's ignitability to designed values. The fuel's ignitability can be calculated without actually igniting the fuel and also without direct knowledge of the fuel's calorific value or its composition.

Abstract: An interface device for an emulator is disclosed. The interface device includes a connection unit, a transmission unit, and an interface unit. The connection unit receives data, to be used to emulate a logic, from a host computer, and transmits result data, output from the logic, to the host computer. The transmission unit receives the data from the connection unit and stores (writes) the data in the first area of a register array. If the result data is stored in the second area of the register array, the transmission unit reads the result data and transmits the result data to the connection unit. The interface unit includes at least one register array, outputs a clock, set using the data stored in the first area, to the logic, and stores the result data, output from the logic, in the second area.

Abstract: A meter is provided that includes an improved user interface that enables the user to take a specific action, leading them directly to data input options. Such a user interface could be used to input first selected information, such as whether a test was premeal or postmeal, immediately after receiving a result. Optionally, the user interface may include the ability to add an additional comment after inputting the first selected information. Provision of such a user interface would facilitate simpler capture of the first selected information each time the user performs a test, leading to an enhanced understanding of a patient's level of glycemic control. Designing a user interface to enable first selected information to be entered by a user directly after receiving a result is more likely to engage a patient by making it easy and simple to enter important information. This may enable capture of the information thought to be most pertinent e.g.

Abstract: Disclosed is a method for determining the quality, expressed in terms of a quality value, of an biomolecule sample, based on measured data of the biomolecule sample, by extracting a number of prescribed features from the measured data using data analysis, and determining the quality value from the extracted features using a quality algorithm.

Abstract: Techniques and systems for displaying chromatographic data using a graphical user interface are provided. Chromatographic separation data that represent multiple series of measurements for multiple samples can be displayed on a display device of a computer system as a series of bands, the bands being arranged to resemble output from an electrophoresis gel. The bands may be aligned using a marker included in each sample.

Abstract: Optical sensor devices, image processing devices, methods and computer readable code computer-readable storage media for detecting biophysical parameters, chemical concentrations, chemical saturations, vital signs and physiological information such as a malignant condition are provided. The optical sensor includes an array of photodetectors, where each photodetector is configured to detect a spectrum of light. Exemplary physiological parameters include but are not limited to a pulse rate, a biophysical or physiological property of skin, a cardiovascular property, a property related to an organ such as the liver or the kidneys, and a temperature fluctuation. Alternatively one or more parameters are detected from a food item such as food tissue, a consumable beverage such as an alcoholic beverage, a dairy product, wine, a baked good, a fruit and a vegetable.

Abstract: In a method for detecting a level of contamination of a particle sensor provided with two electrodes situated on an insulator material for generating an electrical field, the insulator material is heated to above a limiting temperature of the insulator material at which the insulator material begins to become conductive. The insulator material is modulated by heating or cooling, the modulation being carried out at a lower temperature and an upper temperature which are each above the limiting temperature. The variation over time of a measuring signal which may be picked up between electrodes is measured during the modulation. The measured variation over time of the measuring signal is compensated using a theoretical variation over time of the measuring signal in a contamination-free state of the particle sensor in order to obtain a variation over time of a differential signal.

Abstract: A meter is provided that includes an improved user interface that enables the user to take a specific action, leading them directly to data input options. Such a user interface could be used to input first selected information, such as whether a test was premeal or postmeal, immediately after receiving a result. Optionally, the user interface may include the ability to add an additional comment after inputting the first selected information. Provision of such a user interface would facilitate simpler capture of the first selected information each time the user performs a test, leading to an enhanced understanding of a patient's level of glycemic control. Designing a user interface to enable first selected information to be entered by a user directly after receiving a result is more likely to engage a patient by making it easy and simple to enter important information. This may enable capture of the information thought to be most pertinent e.g.

Abstract: A chromatograph analyzing device for automatically executing a base line setting process on an unseparated peak using preset base line conditions. The chromatograph analyzing device includes a separation unit for separating a component included in a sample, and a data processing device for identifying the component of the sample and the quantity of the component in the sample by using a chromatogram obtained from the separation.

Abstract: An MS analysis is performed for each micro area within a specified mass analysis area on a sample. Based on the data obtained by this analysis, a distribution image of a specified m/z ratio of m/z range is created and displayed on a display screen (S10-S14). When an operator selects a substance of interest on the displayed image and indicates its m/z (S15), one or more micro areas in which the MS spectrum intensity at the specified m/z is equal to or higher than a threshold are extracted, and an MS/MS analysis using the m/z of the substance of interest as the precursor is performed on the extracted micro areas (S26 and S27). An average MS/MS spectrum is calculated from the MS/MS spectrum data obtained for those micro areas (S28), and the substance of interest is identified based on the information relating to the peaks appearing on the average MS/MS spectrum (S19).

Abstract: The invention provides a method of sampling conformation space for an interacting pair comprising (a) an approaching body characterized by an approaching body quaternion and (b) a central body characterized by a central body quaternion, wherein the interacting pair is characterized by an energy and a center of mass vector, the method comprising: (i) performing a first minimization of the energy by varying the approaching body quaternion through off-lattice transformations and then, sequentially, (ii) performing a first translation of the approaching body toward the central body along the center of mass vector, wherein the translation consists of an on-lattice transformation.

Abstract: A data matrix in which pixel numbers are assigned to the vertical direction, m/z values are assigned to the horizontal direction, and intensity values are used as terms is generated from data obtained by peak detection (S3), and after the standardization of the data is executed so that the norms of the intensities of the pixel space are set to 1 for each m/z, the peaks (m/z values) are classified into a plurality of clusters by performing clustering in the m/z direction (S5 and S6). Since the probability of isotope peaks or adduct ion peaks derived from the same substance being consolidated into the same cluster increases, unnecessary peaks can be accurately removed by removing unnecessary isotope ion peaks and the like using m/z differences or intensities in the clusters (S7 and S8).

Abstract: Markers are provided for detecting coronary artery disease. Levels of these markers are indicative of a patient being at risk of having or developing coronary artery disease.

Abstract: A field device for measuring the filling level, the pressure or the density of a medium in a container is described. The field device comprises two processors that are separate from each other. The first processor corresponds to a lower safety standard while the second processor corresponds to a higher safety standard. Functions of the field device that are directed towards safety are carried out in the second processor. Functions that are less critical to safety are carried out in the first processor. Data exchange between the two processors is controlled by way of an operating system.