Abstract: Methods and apparatus for rich image capture using focused plenoptic camera technology. A radiance camera employs focused plenoptic camera technology and includes sets of modulating elements that may be used to modulate the sampling of different aspects of the range of plenoptic data. The radiance camera, via the modulating elements, may capture a particular property of light, such as luminance, color, polarization, etc., differently in different microimages or in different portions of microimages. With the focused plenoptic camera technology, the microimages are captured at the same time in a single image. Thus, multiple microimages of the same image of a scene may be captured at different exposures, different colors, different polarities, and so on, in a single image at the same time. Captured images may be used, for example, in High Dynamic Range (HDR) imaging, spectral imaging, polarization imaging, 3D imaging, and other imaging applications.

Abstract: A microscope system which can improve the ease of use and the observation environment when a sample is observed using a microscope formed of a stand and a main body which is removable from the stand. A microscope is formed of a main body and a stand, and the main body is removable from the stand. The main body includes an objective lens, an image optical system, a CCD, a compact monitor and a battery, so that the main body, when removed from the stand, can function independently as a microscope. If the main body is mechanically connected to the stand, the main body and the stand are electrically connected via connectors, and an observation image captured by the CCD is supplied from the main body to the stand via the connectors, and is displayed on a monitor.

Abstract: A scanning microscope for manipulating a sample, the microscope, having a first light source, a second light source, a beam deflector, and an optical device. The first light source is configured to emit an illuminating light beam that follows an illuminating beam. A second light source is configured to produce a manipulating light beam which has a manipulating beam focus and follows a manipulating beam path. The beam deflection device is configured to guide the illuminating light beam and the manipulating beam focus over or through the sample. The optical device is disposed downstream of the second light in the manipulating beam and is configured to modify the size of the manipulating beam focus.

Abstract: A condensing optical system having a condensed light spot with a small size and a large focal depth without causing a problem of a decrease in intensity of the condensed light spot or discontinuity of an intensity distribution in front and rear areas of a focal position is provided. The condensing optical system that condenses a laser beam generated by a laser source at a predetermined focal length is designed to satisfy Expressions (a) to (d), thereby producing 3rd and 5th spherical aberrations: |Z8|?0.1? or |Z15|?0.05?,??(a) Z8/Z15?3 or Z8/Z15<1,??(b) |Z8|<1.4?, and??(c) |Z15|<0.5?,??(d) where ? is a wavelength, Z8 is an 8th coefficient of coefficients of the Zernike fringe polynomial of wavefront aberration corresponding to a 3rd order spherical aberration, and Z15 is a 15th coefficient of the coefficients of the Zernike fringe polynomial of wavefront aberration corresponding to a 5th spherical aberration.

Abstract: A micro-mirror well. In one embodiment the micro-mirror well includes a plurality of planar mirrors arranged around an axis of symmetry and inclined to form a pyramid well, where each of the plurality of planar mirrors is capable of reflecting light emitting from an object of interest placed inside the pyramid well.

Abstract: The invention relates to a method for controlling a surgical microscope (1), wherein the position of the optical system (30) of the microscope (1) is tracked within an operating space by a position tracking system (40), wherein the optical system carrier (20) can be moved by means of a motorized carrier moving system (22, 23, 24). The line of sight of the optical system (30) is automatically set by moving the optical system carrier (20) and is aligned with a pre-defined direction in said operating space.

Abstract: An illumination optical system includes, in order from a light source side a collector lens, a field stop, a field lens having positive power, an aperture stop, and a collective lens having positive power. The illumination optical system is a substantially both-side telecentric optical system between the field stop and a sample surface, and satisfies the following conditional expressions where DFS indicates a diameter of the field stop, ? indicates a magnification from the sample surface to the field stop, and NA indicates a numerical aperture on the sample surface side of the illumination optical system. 15?DFS/??9??(1) 0.85?NA?0.

Abstract: An optical system is described for merging a first and a second partial image beam emanating from a specimen into a resultant image beam allowing modification of the areal proportion of the respective first or second partial image beam in the resultant image beam. A stop arrangement comprises at least a first and a second movable stop element each comprising at least one stop region adapted to be brought into a working position with the first or second partial image beam. Movably arranged connecting means for connecting the two stop elements are provided to modify the respective areal proportions of the partial image beams in the resultant image beam by movement of the connecting means.

Abstract: An optical system which can be detached and attached is constituted such that it is arranged at the object side of an objective optical system for endoscope in which an incidence pupil is arranged, and a middle image of the objective is formed at its inside, and in the arrangement state, the incidence pupil of the objective optical system for endoscope is relayed at a predetermined position which is more projected toward the utmost object side than a surface at the object side in the endoscope. (An incidence pupil which is conjugate with an incidence pupil is arranged at a position which is more projected toward the object side by a predetermined amount than a surface which is at the utmost object side in the endoscope).

Abstract: A method and system for performing three-dimensional holographic microscopy of an optically trapped one dimensional structure. The method and system use an inverted optical microscope, a laser source which generates a trapping laser beam wherein the laser beam is focused by an objective lens into a plurality of optical traps. The method and system also use a collimated laser at an imaging wavelength to illuminate the structure created by the optical traps. Imaging light scattered by the optically tapped structure forms normalized intensity holograms that are imaged by a video camera and analyzed by optical formalisms to determine light field to reconstruct 3-D images for analysis and evaluation.

Abstract: An optical lens is provided in the present invention. The optical lens includes a first curved surface and an annular mask component on and in direct contact with the first curved surface, wherein the annular mask component shields a peripheral annular region of the optical lens from entry of light. The present invention further provides an optical microscope system using the same.

Abstract: A confocal scanning microscope including: an objective system (second objective lens 23 and objective lens 24) illuminating a sample SA with illumination light; a scanning mechanism 31 scanning the sample SA to obtain an intensity signal; and a scanning optical system 32 provided between the scanning mechanism and the objective system. The scanning optical system composed of, in order from the scanning mechanism side, a first positive lens group G1, a second negative lens group G2, and a third positive lens group G3. The third lens group has two chromatic aberration correction portions each formed by a positive lens and a negative lens or negative lens and positive lens. Glass materials are selected such that one performs chromatization and the other performs achromatization, thereby providing a confocal scanning microscope capable of correcting lateral chromatic aberration generated in the objective system in the specific wavelength region by the scanning optical system.

Abstract: A pixel shifting unit moves the relative position between the luminous flux entering an image pickup device and the device to a plurality of predetermined positions in a predetermined order. A control unit controls the device, and allows the image of a subject image formed by the luminous flux on the photoreception surface of the device when the relative position is in any of the plurality of predetermined positions. A combination unit combines the plurality of obtained images to generate a high-resolution image. A prediction unit predicts a shooting environment when the device hereafter shoots an image of the subject image on the basis of a change of at least two images. A setting control unit controls a setting of a shooting condition when the image of the subject image is shot on the basis of a result of the prediction of the shooting environment.

Abstract: A control system and apparatus for use with an ultra-fast laser is provided. In another aspect of the present invention, the apparatus includes a laser, pulse shaper, detection device and control system. A multiphoton intrapulse interference method is used to characterize the spectral phase of laser pulses and to compensate any distortions in an additional aspect of the present invention. In another aspect of the present invention, a system employs multiphoton intrapulse interference phase scan. Furthermore, another aspect of the present invention locates a pulse shaper and/or MIIPS unit between a laser oscillator and an output of a laser amplifier.

Abstract: A microscope with sub-wavelength resolution with a light source for monochromatic light with a predetermined wavelength, an object carrier for an object to be examined, and an image sensor with an optical structure with a first side and a second side opposite to the first side, the optical structure having a negative refractive index, and a pixel array extending along the second side of the optical structure at a predetermined distance, wherein the first side of the optical structure of the image sensor is arranged at a near-field distance smaller than the wavelength of the monochromatic light to the object carrier.

Abstract: Observation is performed using bright, clear multiphoton fluorescence images produced by efficiently generating a multiphoton excitation effect, without the need for a complex interference film structure. The invention employs a laser microscope apparatus including a first dichroic mirror that reflects visible laser light guided via a first light path and that transmits IR pulsed laser light guided via a second light path to combine the first light path and the second light path; an XY galvanometer mirror that scans the laser light from the first dichroic mirror on a specimen; an objective lens that irradiates the specimen with the scanned laser light and that collects fluorescence produced in the specimen; a second dichroic mirror that reflects the visible laser light and transmits the fluorescence from the specimen; and a detection unit that detects the fluorescence transmitted through the second dichroic mirror.

Abstract: A method of imaging light from a specimen in which excitation light passes to the specimen via a scanning system and light emitted by luminescence of the specimen passes in another direction via the scanning system to an image capture device having a sensor having discrete spatially distinct light sensitive regions. The scanning system is operated to scan the whole of an area of interest of the specimen, and the excitation light and/or the image capture device are controlled so that light emitted from the specimen in only incident on the image capture device sensor for a specific time period equal to that required for scanning the whole of the area of interest n time. The scanning system is a confocal system. Apparatus is provided for performing the method to produce a video signal for creating an image in a display device or for processing and analysis by a computer.

Abstract: A microscope or stereomicroscope for representing an object that can be placed on an object plane of the stereomicroscope provides at least one pair of optical paths and comprises at least one deflection element with a reflecting surface and a representation system containing several optical elements. The optical elements include a plurality of lenses. In addition, the optical elements are configured in such a way that pupil planes of the optical representation paths intersect the reflecting surface of the deflection element or are located at a distance from said reflecting surface less than 1.5 times the diameter of one of the reflecting surfaces along the optical representation paths on the closest lens of the plurality of lenses. An alternative embodiment provides a stereomicroscope with a particularly compact construction, in which at least one pair of optical representation paths is reflected on a first, second, third, and fourth reflecting surface.

Abstract: Control apparatus for a microscope having at least one rotary control member for adjustment of the microscope, the apparatus comprising: a motor; a coupling arrangement driven, in use, by the motor; and a mount arrangement to provide adjustable positioning of the motor relative to the control member, to cause the coupling arrangement to engage the rotary control member to cause the control member to be driven by rotation of the motor.

Abstract: An objective lens to be fitted into a fitting hole of a nosepiece of a microscope includes an imaging lens that is composed of a plurality of lens groups, and a lens barrel that holds the imaging lens. The lens barrel is formed with a fitting portion that is fitted to the fitting hole of the nosepiece and provided at an outer circumference of a tip portion side away by a given distance from the tip portion where a first lens group in the imaging lens is held, and a mount surface that comes into contact with a contact surface of the fitting hole of the nosepiece upon fitting at the fitting portion. The nosepiece is equipped with the objective lens. The inverted microscope is equipped with the nosepiece fitting the objective lens.

Abstract: A method for acquiring signals in laser scanning microscopy, includes the steps of: moving a focused optical excitation beam relative to an object to be measured so that the focus point of the beam follows a predetermined path in the space of the object; and acquiring optical measurement signals along the path according to at least one acquisition parameter; characterized in that the path of the excitation beam is determined so as to substantially minimize the variations of the optical properties of at least one portion of the environments crossed by the excitation beam between consecutive acquisitions, and in that at least one acquisition parameter among the acquisition parameters is modulated during the movement of the excitation beam. A device for implementing the method is also described.

Abstract: The present invention is low cost, does not exert a negative influence on the surroundings, has a small group-velocity delay dispersion, efficiently blocks reflected return light such that the laser light does not return to the laser light source, and allows properly polarized laser light to enter a polarization-dependent element in a subsequent stage. An optical device is provided which includes a laser light source, an optical system that transmits laser light emitted from the laser light source, and a polarization-dependent element into which the laser light transmitted by the optical system enters. The characteristics of outgoing light are changed according to a polarization state of the incident light. The optical system includes a reflected-light generator that reflects a part of the transmitted laser light, and ?/4 wave plates are disposed such that the reflected-light generator is disposed therebetween.

Abstract: A configuration for the optical detection of a specimen, wherein the specimen or at least part of the specimen is scanned by means of linear illumination by scanning means, means for linear beam shaping of the illuminating light are provided, and the illuminating light has a preferably periodic structure in at least one spatial direction in that means for generating the structure are disposed in the illuminating beam path, light coming from the specimen is detected and images of the specimen are generated therefrom, at least one optical sectional image through the specimen and/or one image with increased resolution is/are calculated from the images, and means for generating the structure are disposed downstream of the scanning means in the direction of the illumination.

Abstract: A device for holding filters for a microscope includes a filter wheel (20) rotatable about an axis of rotation (16) and a drive unit (14) for rotating the filter wheel (20). The filter wheel (20) comprises a basic body (44) rotatable about the axis of rotation (16) and at least one segment (46-54) selectively connectable to the basic body. The segment (46-54) comprises at least two housing areas (58, 59) each holding at least one filter (11). Another housing area may provide a transmission range (36, 59) for unfiltered transmission of light. A second rotatable filter wheel may be arranged at a location displaced along the axis of rotation relative to the filter wheel, and may have its own respective transmission range for unfiltered transmission of light, whereby a filter on either filter wheel may be aligned with the transmission range on the other filter wheel.

Abstract: An apparatus for electrical inspection is disclosed. The apparatus comprises an inert gas delivery system that delivers inert gas near a microscope imaging element and electrical test probes. A gas supply provides an inert gas such as argon or nitrogen. The inert gas displaces oxygen to prevent premature oxidation of the test probes. In one embodiment, one or more delivery tubes deliver inert gas to the measurement area.

Abstract: Observation over a superwide field of view is possible with a short, lightweight, and inexpensive eyepiece optical system and a binocular barrel. A microscope optical system includes an objective optical system configured to collect light from a specimen; an imaging optical system configured to image the light coming from the specimen and collected by the objective optical system; and an eyepiece optical system configured to magnify the image of the specimen formed by the imaging optical system and form a virtual image in an eye of an observer, wherein the following conditional expressions are satisfied, M=Fntl/Fob×250/Fne??(1) Fntl=Ftl×Kt??(2) Fne=Fe×Kt??(3) 0.4<Kt<0.

Abstract: A multi-mode optical fiber delivers light from a radiation source to a multi-focal confocal microscope with reasonable efficiency. A core diameter of the multi-mode fiber is selected such that an etendue of light emitted from the fiber is not substantially greater than a total etendue of light passing through a plurality of pinholes in a pinhole array of the multi-focal confocal microscope. The core diameter may be selected taking into account a specific optical geometry of the multi-focal confocal microscope, including pinhole diameter and focal lengths of relevant optical elements. For coherent radiation sources, phase randomization may be included. A multi-mode fiber enables the use of a variety of radiation sources and wavelengths in a multi-focal confocal microscope, since the coupling of the radiation source to the multi-mode fiber is less sensitive to mechanical and temperature influences than coupling the radiation source to a single mode fiber.

Abstract: The aim of the invention is an optical device for a scanning microscope, said device enabling the focusing of a light beam largely independent of wavelengths; and thus high-resolution microscopy, in particular STED microscopy, in a wider wavelength spectrum is facilitated. At least two phase filters lie on a support. Advantageously, the support is a filter wheel or a filter slider which can be introduced into the beam path of the light beam, said beam path preferably being the beam path of the stimulating light beam in an STED microscope. Several phase filters preferablylie on the support in the shape of a matrix. The support is designed as a glass substrate on which each phase filter is applied. To achieve said aim, another position is additionally found on the support for adjustment purposes, wherein the wavefront of the light is not influenced when it passes through said position, that is, the position is an empty position on which no phase filter is found.

Abstract: Provided is a nonlinear optical device capable of alleviating, without the need for a complicated compensation mechanism, temporal broadening and the waveform distortion resulting from a group-velocity dispersion slope, to thereby irradiate an object with short optical pulses having high peak power. The nonlinear optical device includes a short optical pulse source (10) for generating short optical pulses and a short optical pulse delivery system (20) for delivering the short optical pulses generated from the short optical pulse source to an object, in which there is generated substantially no nonlinear optical effect and there is substantially no amount of group-velocity dispersion, the short optical pulse source generates short optical pulses, and the short optical pulses have a spectral width (full width at half maximum) ?FWHM satisfying ?1<?FWHM<?2.

Abstract: A laser scanning microscope is disclosed that combines light from first and second scanning optical systems onto a common optical path using a beam combiner. A first plane-parallel transparent plate and a beam combiner are positioned on a support that may be moved relative to the common optical path. The first plane-parallel transparent plate has an optical thickness equal to the optical thickness of the beam combiner and is oriented with its surface normal lying substantially parallel with the surface normal of the beam combiner. An astigmatism-correcting optical element is provided on the common optical path, with the astigmatism-correcting optical element generating astigmatism that is equal in magnitude, but different in direction by 90 degrees, to the astigmatism generated by non-collimated light that is transmitted through the beam combiner. When the support is repositioned, spherical aberration in various light paths is maintained constant so that it may be easily corrected.

Abstract: A surgical observation system provided with a supporting arm movable in the three-dimensional direction includes an endoscope objective unit having a tubular insertion section and provided with objective optical systems, a microscope objective unit provided with objective optical systems having a focusing optical system and variable magnification optical systems, and a mounting and dismounting section provided in the supporting arm, mountable and dismountable with respect to the objective units by having interchangeability.

Abstract: The present application generates an image suitable for collectively observing a whole area or all wavelength components in a viewing field. A confocal microscope apparatus includes a detecting unit being disposed on a collecting location of the collecting optical system, separating incident light into a light from a vicinity of a collecting point on the sample and a light from a peripheral of the vicinity, and detecting each of the lights; and an image generating unit generating an image of the sample by a light signal from the vicinity and a light signal from the peripheral of the vicinity, and setting a ratio of the signal of the light from the vicinity of the collecting point to the signal of the light from the peripheral of the vicinity for each of areas on the image.

Abstract: A microscope assembly includes an illumination source coupled to an optical assembly by a coupler. The optical assembly includes an objective with optics that move along an optic axis. The illumination source generates a light blade that illuminates a portion of a sample at an illumination plane. The light blade induces a fluorescent emission from the sample that is projected through the objective optics to a detector. The focal plane of the objective optics is fixed with respect to the illumination source by the coupler so that the illumination plane is coincident with the focal plane as the objective optics move along the optic axis. The objective and illumination may be rapidly scanned along the optic axis to provide rapid three-dimensional imaging while the objective and illumination may also be rapidly scanned along the optic axis to provide rapid three-dimensional imaging.

Abstract: An object of interest is illuminated within the field of view of a microscope objective lens located to receive light passing through the object of interest. Light transmitted through the microscope objective lens impinges upon a variable power element. The variable power element is driven with respect to the microscope objective lens to scan through multiple focal planes in the object of interest. Light transmitted from the variable power element is sensed by a sensing element or array.

Abstract: A microscope includes a main body, a transmitted light source, and a transmitted-light illumination optical system. The main body has a substantially C-shape when viewed from side, and is composed of a lower horizontal portion, an upper horizontal portion, and a brace portion. The brace portion connects between the lower horizontal portion and the upper horizontal portion on their rear side. The transmitted-light illumination optical system brings an illumination light from the transmitted light source to a specimen supported by the main body, and illuminates the specimen with the illumination light transmitted therethrough. The transmitted-light illumination optical system and the transmitted light source are removably attached to the lower horizontal portion of the main body.

Abstract: An apparatus includes: an image pickup unit capturing a color image observed by the microscope; a camera characteristic information storage unit storing camera characteristic information about a characteristic of the microscope color image pickup apparatus; a color correction parameter calculation unit calculating a color correction parameter for a color correcting process on the color image captured by the image pickup unit according to the color image captured by the image pickup unit and the camera characteristic information stored in the camera characteristic information storage unit; and a color correcting unit performing a color correcting process on the color image captured by the image pickup unit according to the color correction parameter calculated by the color correction parameter calculation unit.

Abstract: A microscope image pickup system includes: alight source; an object lens; a display device; a record device; a capture device for performing a preview mode in which an image of the test object obtained by the object lens is repeatedly captured and a plurality of captured images are continuously displayed on the display device, or an image record mode in which the image of the test object is captured and the captured image is recorded on the record device; an illumination light amount control device for controlling the amount of light of the illumination light; and a system control device for controlling an operation of the illumination light amount control device depending on the preview mode or the image record mode performed by the capture device.

Abstract: Methods and apparatus for capturing and rendering images with focused plenoptic cameras employing different filtering at different microlenses. In a focused plenoptic camera, the main lens creates an image at the focal plane. That image is re-imaged on the sensor multiple times by an array of microlenses. Different filters that provide different levels and/or types of filtering may be combined with different ones of the microlenses. A flat captured with the camera includes multiple microimages captured according to the different filters. Multiple images may be assembled from the microimages, with each image assembled from microimages captured using a different filter. A final image may be generated by appropriately combining the images assembled from the microimages. Alternatively, a final image, or multiple images, may be assembled from the microimages by first combining the microimages and then assembling the combined microimages to produce one or more output images.

Abstract: The invention provides microfluidic devices, methods for imaging cells, and methods for preparing such microfluidic devices. The microfluidic devices are contemplated to provide advantages for use in imaging of cells and subcellular compartments in an environment that mimics in vivo conditions. The microfluidic devices can used with a microscope equipped with an oil emersion objective lens.

Abstract: There is disclosed an operation microscope in which an observing and displaying system of an operating instrument are selected, and an endoscope image for observing a dead angle of the microscope and a navigation image are selectively displayed in a microscope observation field, so that a tomographic image, three-dimensionally constructed image, and the like can be selectively displayed in a display screen in accordance with a treatment position displayed in a monitor or an observation position of the operation microscope.

Abstract: To irradiate a laser beam appropriately onto a patient's eye. An ophthalmic apparatus having a laser irradiation optical system irradiating a laser beam for corneal surgery onto the eye, which performs alignment of a reference axis of the optical system to have a predetermined positional relationship with the eye to perform laser irradiation, includes movement means changing inclination and a position of the optical system with respect to the eye, first and second image-pickup means picking up anterior-segment images having image-pickup optical axes arranged in different directions and to have predetermined positional relationships with the reference axis, detection means for detecting inclination and a position of the eye with respect to the reference axis by subjecting the images by the image-pickup means to image processing, and control means controlling the movement means to bring the reference axis to an intended alignment state with the eye based on a detection result.

Abstract: An illumination device for a microscope has a variable working distance (d, d?), at which an object is illuminated obliquely from two different directions. Light from a light source is split into at least two illumination beam paths. In order to adapt to the different working distances, the light is subjected to an angle change before splitting or, if after splitting, then respectively by the same amount in both beam paths. A deviating element with at least two reflective surfaces is arranged in one of the illumination beam paths to induce a change in an angle at which one of the illumination beam paths strikes the object, in the same sense as another illumination beam path. The reflective surfaces may be arranged so that the illumination beam paths strike essentially the same region of the optical axis even with different working distances.

Abstract: A method of performing 3D photoactivation microscope imaging includes providing a sample having a plurality of probes, each of the plurality of probes including a photo-activatable material. Probes from the plurality of probes are activated to form a sparse subset of probes, the sparse subset of probes having probes that are spatially separated by at least a microscope resolution. The sample is illuminated with a readout light source, and light emitted from activated probes is detected. Based on the light emission detected from the activated probes, localized three-dimensional positions of the activated probes are obtained.

Abstract: The invention provides an apparatus for electromagnetically affecting a particle of interest in a specimen. The apparatus includes (a) a stage capable of supporting the specimen; (b) a detector including at least one camera, wherein the detector is capable of resolving a particle of interest within the specimen; (c) a means for locating the particle of interest in three dimensions; (d) a means for focusing electromagnetic radiation to a focal volume within the specimen; and (e) a means for adjusting the relative positions of the stage and electromagnetic radiation focusing means, thereby positioning the particle of interest within the focal volume.

Abstract: An embodiment of the present invention provide for an optical microscope apparatus including a light source, a base unit, a rotary monochromatic dispersion unit, a condenser, a stage, an objective, a tubular assembly and an ocular assembly. In a preferred embodiment, light travels from the light source sequentially through each of these seven components, producing an image of the contents of a slide on the stage to a user looking through the ocular assembly. In the base unit, in place of a standard mirror which would direct the light vertically up into the scope along the z-axis, a right angle piece of single crystal Calcite, known as Iceland Spar is used, which has a birefringent affect upon the light as it passes up through the scope.

Abstract: A focus detection apparatus is provided with a light source 16 that emanates light with a given wavelength range; a reflection member 15 that reflects light emanated from the light source 16 to lead to an object 6a, reflects light from the light source 16 reflected from the object 6a, and transmits light from the object 6a with at least two different wavelength ranges except the light reflected from the object 6a; a photodetector 21 detecting the light from the light source 16 reflected from the object 6a; and a controller 22 detecting a focus shift between the objective lens 8 and the object 6a in the microscope 2 based on a signal detected by the photodetector 21, thereby providing a focus detection apparatus capable of limiting wavelength range of light for focus detection thereby able to use wider wavelength range for the microscope observation, and a microscope equipped therewith.

Abstract: An optical imaging system including an imaging lens and a spatial light modulator is provided. The imaging system has an aperture stop position. The spatial light modulator is disposed at the aperture stop position of the imaging system to serve as a pupil of the imaging lens. The spatial light modulator is adapted to modulate the light transmission rate of the spatial light modulator to change an amplitude and a phase of a light intensity of the pupil.

Abstract: In intraocular observation of the eye, the slit lamp microscope 1causes the illumination light emitted by the illumination system 8 to enter the inside of the eye via the head lens 20 and causes an intraocularly reflected light of this illumination light to enter the observation system 6 via the head lens 20 in a state that an illumination optical axis O2 and an observation axis O1 are arranged so as to be nonparallel and a head lens optical axis OF and the observation optical axis O1 are arranged so as to be separate right and left.

Abstract: A device and method for adjusting mounting of a microscope stage (14), to which an objective (38) is mounted, to a microscope stand (12), including at least one first connecting element (56) arranged on the microscope stand (12), at least one second connecting element (62) arranged on the microscope stage (14) for mounting the microscope stage (14) to the microscope stand (12), at least one first mating part (76) arranged on the microscope stand (12), at least one positioning base (66) supporting a second mating part (74), wherein the positioning base (66) adjusts the platform (16) on the microscope stand (12) and is mounted movably in a plane of adjustment that is parallel to the platform (16) with the mating parts (74, 76) being engaged, and at least one locking device (80) for locking the positioning base (66) to the platform (16).

Abstract: There is provided an electron microscope which is capable of making a significant contribution to accomplishment of efficiency in investigating causes for pattern abnormalities found out. The electron microscope including an I/O for capturing image data on a microscopic image acquired by another electron microscope, a computation processing unit for generating a display signal based on the image data on the microscopic image acquired by another electron microscope and captured via the I/O and image data on a microscopic image acquired by the electron microscope itself, in order that the microscopic image acquired by another electron microscope and the microscopic image acquired by the electron microscope itself are displayed at the same scale and under the same display condition, and a display unit for displaying both of the microscopic images based on the display signal from the computation processing unit.