Abstract: Methods and apparatus for an intraocular lens with a proofed surface are disclosed. The proofed surface functions as a barrier to fluid diffusion inside the material and within vacuoles. By preventing the interstitial filling of fluid, the formation of spots inside the polymer matrix is inhibited or reduced. The proofed surface of the intraocular lenses is a highly stable re-assembled surface without any coating or grafting.

Abstract: When fitting a patient for an intraocular lens, a series of measurements is taken on the patient's eye that determines a required lens power. Next, a range of preferred shape factors may be found, which determine the base (i.e., spherical) radii of the two lens surfaces, essentially independent of the lens power. The preferred shape factor adjusts the third-order coma of the lens to largely offset the coma of the cornea, so that the image at the retina has a reduced amount of third-order coma. Once a preferred shape factor is determined, the base radii of curvature of the anterior and posterior surfaces are determined from the shape factor and the lens power by algebraic formulas. Finally, one or more aspheric terms are added to one or both of the surfaces in the lens, so that the spherical aberration of the lens largely offsets the spherical aberration of the cornea.

Abstract: Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver. The energy receiver is configured to receive light emitted from the external non-visible light source, and extract energy from the emitted light for powering the intraocular device. The intraocular device is configured to regulate a parameter of operation of the intraocular device based on a modulation of the light emitted by the external non-visible light source and received by the energy receiver. Other embodiments are also described.

Abstract: A method for calculating the required power of a toric implant by using both the measured pre-operative corneal astigmatism and the predicted surgically-induced post-operative astigmatism. The surgically-induced post-operative astigmatism is predicted using power vector analysis of the surgical technique employed by the surgeon. Such a method provides a more accurate method of calculating the required post-operative refractive power of the implant. The method can be implemented manually, but preferably is automated by implementation on a computer through appropriate software.

Abstract: Described is the use of polymers with a high refractive index for ophthalmic products and a process for the production thereof.

Abstract: The present invention provides a contact lens manufactured at least partially from an intelligent polymer, the lens having a relaxed state which, upon application of a first stimulus forms a first corrective shape and which, upon application of a second stimulus, forms a second corrective shape, wherein the corrective effect provided by the lens in the relaxed state is intermediate to the corrective visual effects provided by the first and second corrective shapes.

Abstract: An article for use in an OCT method, the article comprising a solid substrate and nanoparticles dispersed in or on the substrate in at least one light transmissive portion of the article such that the nanoparticles result in an increased extinction of the light transmissive portion along a transmission direction of the light transmissive portion compared to the substrate being free of nanoparticles. The extinction of the light transmissive portion along the transmission direction is less than 6, wherein the extinction is defined as a negative decadic logarithm of a ratio of an intensity of light which is transmitted through the light transmissive portion to an intensity of light which is incident on the light transmissive portion, wherein the light is in at least one of a visible and a near infrared wavelength range.

Abstract: Disclosed are soft, high refractive index, acrylic device materials. The materials contain a hydrophilic side-chain macromer for glistening resistance.

Abstract: Disclosed are devices, methods and systems for treatment of eye disease, including open angle glaucoma and narrow angle glaucoma. Implants are described herein that create a directed flow field, such as between the anterior chamber and either the supraciliary space or suprachoroidal space. In addition, the implant can include a variety of features, including extruded features, such as rings and pegs, which can assist in preventing ocular tissue from collapsing onto the implant and occluding fluid pathways.

Abstract: An improved prosthesis and method for stimulating vision nerves to obtain a vision sensation that is useful for the patient that has lost vision due to age-related macular degeneration (AMD) and retinitis pigmentosa (RP) and other diseases. The present invention utilizes infrared light to cause action potentials in the retinal nerves similar to those which result from rods and cones stimulated by visible light in healthy retinas. In some embodiments, the invention provides a pathway or “image pipe” for transmitting a stimulation pattern of infrared light from an external stimulator array through the eye and focusing the stimulation pattern of infrared light on the retina, especially the fovea. Some embodiments provide improved resolution down to a group of nerves, or even the individual nerve level, with sufficient energy density so as to cause a desired action potential.

Abstract: The present invention relates to devices, systems and methods for determination or selection of a lens power based on the postoperative vitreous length of an eye. The combined measurements of VLpre, ACDpre, AL, and/or LT are highly predictive in calculating the postoperative vitreous length, from which the position of the implanted intraocular lens or optic can be derived, and then selection of the appropriate lens power.

Abstract: The present invention relates to devices, systems and methods for determination or selection of a lens power based on the postoperative vitreous length of an eye. The measurement of VLpre is highly predictive in calculating the postoperative vitreous length, from which the position of the implanted intraocular lens or optic can be derived, and then selection of the appropriate lens power.

Abstract: A lens in accordance with the present invention includes an switchable cell consisting of optical substrate with diffraction surface, elastic film in contact with the diffraction surface of the substrate, optical fluid that fills the space between the film and diffraction surface and the mean to transfer the optical fluid in and out of the space between the film and diffraction surface. The refractive index of the optical fluid matches the refractive index of the optical substrate. The switchable cell changes focus positions between refractive focus in relaxed state when the pressure at both sides of the film is the same and diffraction focus when the optical fluid is transported from the space between the film and optical substrate for the film to largely conform to the diffraction surface shape of the optical substrate.

Abstract: The present invention relates generally to lens design and, more particularly, to a method for designing, evaluating and optimizing ophthalmic lenses and laser vision correction in order to optimally manage issues resulting from, or related to, halos.

Abstract: Provided is a technique which, in the design of intraocular lenses, simplifies design work and makes it possible for aberration of the entire eyeball to more precisely match a target value when the designed intraocular lens is inserted into a patient's eye. This intraocular lens design method involves deriving an intraocular lens aberration target value from the aberration of the cornea and anterior chamber and a set value of the total eyeball aberration (S102), and determining an intraocular lens shape such that the at least the aberration of the intraocular lens coincides with the target value (S103-S107). The intraocular lens aberration is set to an intraocular lens aberration for which prescribed convergent light is incident to the intraocular lens (S104).

Abstract: In certain embodiments, determining physical lengths of an eye includes determining an optical length of each segment of a plurality of segments of an axis of the eye, where each segment corresponds to a portion of the eye. A refractive index is determined for each segment. A physical length of each segment is determined according to the optical length and the refractive index of the segment.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: The invention relates to the field of ophthalmic systems and procedures. In particular, the invention relates to the determination of the post-operative position of an intraocular lens (termed “IOL”) in an eye of a patient undergoing lens replacement surgery, which involves determining the position of the existing crystalline lens in the pre-operative eye of the patient and using that information and a single numerical constant to predict the post-operative intraocular lens position. Related methods, and computer programs for performing the methods of the invention, are also disclosed.

Abstract: Apparatus and methods to increase the depth of field in human vision in order to correct for loss in refocusing ability. Optics variations, such as changes in thickness, shape, or index of refraction of contact lenses, intraocular implants, or the shape of the cornea or eye lens, affect the phase, or wavefront, of the light perceived by the eye. The optics variations are chosen such that the resulting optical transfer function remains relatively constant over a desired range of object distances and pupil diameters.

Abstract: UV absorbing compounds that are effective in blocking UV and short-wavelength blue light are disclosed. The UV absorbing compounds are particularly suitable for use in intraocular lens materials.

Abstract: Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

Abstract: The present invention relates to a method of determining the IOL refractive index for an ocular replacement material for replacing tissue in the capsular bag comprising combining a neutral (non-correcting) reference refractive index (“NRRI”) of between 1.421 and 1.450 with a refractive index correction factor (“RICF”) ascertained by reference to the refractive power required to correct the patient's refractive error. The present invention also relates to methods of treating presbyopia, myopia and hyperopia using the above method.

Abstract: Disclosed are soft, high refractive index, acrylic device materials. The materials contain a functionalized alkylphenol ethoxylate to reduce glistenings.

Abstract: An intraocular lens for providing vision to a subject contains an optic, a support structure coupled to the optic. The intraocular lens also includes a textured surface and/or subsurface layer. The optic is disposed about an optical axis and comprises an anterior surface and an opposing posterior surface, the surfaces being configured to focus light when implanted within an eye having a capsular bag. The textured surface is disposed over a surface portion of the intraocular lens and includes a plurality of periodically-spaced protrusions, each protrusion having a smooth distal face and a sharp corner edge configured to engage a wall of the capsular bag and/or at least one cell disposed along the wall.

Abstract: An improved dual-filter lens for protective eyewear that combines a first filter for blocking essentially 100% of UV light, and second filter for filtering blue light. The first filter may comprise a multi-layered dielectric mirror layer 14 or Rugate filter 50, and the second filter may comprise dye-impregnated lens layer(s) 16, 18 or Rugate filter 50. The first filter blocks essentially 100% of UV light, while the second filter establishes an increasing transmission profile that cuts on sharply at approximately 415 nm, and establishes an increasing transmission profile between approximately 415 nm to about 475 nm. The cut-on slope rises approximately 0.15% in transmissivity for every nanometer of increasing wavelength change, with a maximum filtering effect within the 440-465 nm range. These dual filters provide a balanced light transmission profile that reduces harmful tight transmission and prevents macular degeneration, cataracts and other ocular injuries, while still preserving visual acuity.

Abstract: An intraocular lens for correcting or reducing the astigmatism of a cornea includes a pupil that is spatially divided into discrete zones, with each zone having a particular astigmatism magnitude and astigmatism orientation. In one embodiment, the zones all have the same astigmatism magnitude, which is equal and opposite the cornea astigmatism magnitude to within a particular tolerance, such as 0.25 diopters. In one embodiment, some or all of the zones all have different astigmatism orientations, with the angular separation between astigmatism orientations being on the order of the rotational misalignment tolerance of the lens to the cornea. The visual performance of such a lens deteriorates more slowly with rotational misalignment, when compared to a comparable lens having a uniform astigmatism orientation across its entire pupil, leading to more relaxed tolerances for a surgeon that implants the lens.

Abstract: Disclosed are low-tack, hydrophobic, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers, a tack-reducing macromer additive and a glistening-reducing additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other implantable ophthalmic devices.

Abstract: In certain embodiments, calculating intraocular lens (IOL) power includes determining locations of parts of an eye along an axis of the eye. The locations include the location of a cornea, the anterior and posterior locations of a crystalline lens, and the location of a retina. An IOL location of an IOL is calculated according to the anterior and posterior locations of the crystalline lens. Corneal data is also determined. The IOL power is calculated using the corneal data, the IOL location, and the retinal location. In certain embodiments, refractive indices are determined for segments of the axis, and at least one location is adjusted according to the refractive indices.

Abstract: A refractive intraocular lens (104) and method of locating the lens within the eye and attaching the lens to the iris. The refractive intraocular lens (104) may be attached via a staple (230), a fastener (312), anchor (412) or by the tip of the haptic (118). The intraocular lens (104) works in combination with the human crystalline lens to treat conditions selected from the group consisting of myopia, hyperopia and astigmatism.

Abstract: A system controller for an ophthalmic lens comprising an electronic system which actuates a variable-focus optic is disclosed herein. The system controller is part of an electronic system incorporated into the ophthalmic lens. The electronic system includes one or more batteries or other power sources, power management circuitry, one or more sensors, clock generation circuitry, control algorithms and circuitry, and lens driver circuitry. The controller including multiple state machines configured as digital logic gates.

Abstract: The invention discloses an optical coupling gel that has a set of desired features for application in eye imaging, including being approved for eye contact, optically transparent, able to maintain normal hydration of the ocular surface, flexible and capable of maintaining a distinct shape, minimal in breakdown/change during use, and easily dispensable/applicable. In one embodiment, the gel is made of Sodium Carboxy Methylcellulose (SCMC), where the amount of the cellulose determines the viscosity of the gel for its particular application. The right amount of gel is contained in an applicator for application to one or two eyes.

Abstract: An improved dual-filter lens for protective eyewear that combines a first filter for blocking essentially 100% of UV light, and second filter for filtering blue light. The first filter may comprise a multi-layered dielectric mirror layer 14 or Rugate filter 50, and the second filter may comprise dye-impregnated lens layer(s) 16, 18 or Rugate filter 50. The first filter blocks essentially 100% of UV light, while the second filter establishes an increasing transmission profile that cuts on sharply at approximately 415 nm, and establishes an increasing transmission profile between approximately 415 nm to about 475 nm. The cut-on slope rises approximately 0.15% in transmissivity for every nanometer of increasing wavelength change, with a maximum filtering effect within the 440-465 nm range. These dual filters provide a balanced light transmission profile that reduces harmful light transmission and prevents macular degeneration, cataracts and other ocular injuries, while still preserving visual acuity.

Abstract: Antennas and antenna systems may be designed and configured for incorporation into mechanical devices, including medical devices, such as ophthalmic devices, including contact lenses. These antennas and antenna systems may be utilized to transmit data from the mechanical device to a receiver, to receive data from a transmitter, and/or to inductively charge an electromechanical cell or the like incorporated into the mechanical device.

Abstract: A refractive intraocular lens (104) and method of locating the lens within the eye and attaching the lens to the iris. The refractive intraocular lens (104) may be attached via a staple (230), a fastener (312), anchor (412) or by the tip of the haptic (118). The intraocular lens (104) works in combination with the human crystalline lens to treat conditions selected from the group consisting of myopia, hyperopia and astigmatism.

Abstract: The material of the invention is obtained by radical polymerization from a mixture of acrylic and/or methacrylic monomers. The mixture further contains at least one transfer agent, preferably from the thiol family, that substantially enhances the flexibility of the polymer material thus obtained, and reduces the tackiness thereof. The polymer material thus obtained is intended for making ophthalmologic implants, and more particularly, intraocular lenses.

Abstract: Disclosed are low-tack, hydrophobic, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers, a tack-reducing macromer additive and a glistening-reducing additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other implantable ophthalmic devices.

Abstract: The present invention relates to an adjustable ophthalmic lens comprising at least one optical element comprising a combination of at least two optical surfaces wherein both optical surfaces are chiral optical surfaces adapted to provide chiral modulation of the light beam, the combination of the chiral optical surfaces is adapted to provide at least one adjustable focus and the combination of the chiral optical surfaces is adapted such that the focal distance of the adjustable foci depends on the mutual position of the chiral optical surfaces. These chiral optical surfaces result in a chiral modulation of the light beam. Combinations of chiral optical surfaces are applied to obtain adjustable optical powers in single-focus ophthalmic lenses and multiple-focus ophthalmic lenses.

Abstract: The present invention relates to a method of determining the IOL refractive index for an ocular replacement material for replacing tissue in the capsular bag comprising combining a neutral (non-correcting) reference refractive index (“NRRI”) of between 1.421 and 1.450 with a refractive index correction factor (“RICF”) ascertained by reference to the refractive power required to correct the patient's refractive error. The present invention also relates to methods of treating presbyopia, myopia and hyperopia using the above method.

Abstract: A multifocal ophthalmic device is disclosed, wherein the lens body comprises a curcuminoid compound as a UV-light stabilizer, and/or a co-polymeric composition which is derived from a pre-polymerization mixture of defined monomers The lens body of the multifocal ophthalmic device is being formed with a plurality of concentric annular zones, which effect both diffraction and refraction of incident light, and which are separated by slanted steps that are substantially devoid of any diffractive or refractive power.

Abstract: Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.

Abstract: Disclosed are apparatus for delivering an accommodating intraocular lens to an eye. One apparatus includes an injector with a longitudinal injection passage that has a longitudinal injection axis. The apparatus also includes an accommodating intraocular lens having two interconnected viewing elements. The injector has a member for moving the lens into the injection passage of the apparatus. The accommodating intraocular lens has a longitudinal bisection axis and is initially disposed within the injector with the longitudinal bisection axis at an angle which is non-parallel and non-perpendicular to the injection axis. Additional apparatus and methods are disclosed as well.

Abstract: Described herein are devices, compositions, and methods for improving color discernment.

Abstract: System, ophthalmic lens, and method for extending depth of focus includes an optic having a clear aperture disposed about a central axis. The optic includes a first surface and an opposing second surface. The first and second surfaces are configured to introduce an asymmetric aberration to the eye while maintaining the in-focus visual acuity.

Abstract: An improved intraocular lens, for example, an accommodating intraocular lens including a lens optic or lens optic portion provided with a light window.

Abstract: An imaging lens structure and method of imaging are presented. The imaging lens structure comprising a lens region defining an effective aperture of the lens structure. The lens region comprises an arrangement of lens zones distributed within the lens region and comprising zones of at least two different optical functions differently affecting light passing therethrough. The zones of at least two different optical functions are arranged in an interlaced fashion along said lens region corresponding to a surface relief of the lens region such that adjacent lens zones of different optical functions are spaced apart from one another along an optical axis of the lens structure a distance larger than a coherence length of light at least one spectral range for which said lens structure is designed.

Abstract: An intraocular implant adapted to be implanted within the interior of a human eye is disclosed. The aforesaid implant is selected from a group consisting of: an intracorneal implant, an anterior chamber implant, a sulcus implant, implant in the bag, posterior chamber implant and any combination thereof. The implant comprises means selected from a group consisting of reflective surfaces and electronic device. The implant is adapted to form at least one image of at least part of the field of vision on the retina. The image is selected of a group consisting of: artificial image and reflected image, and any combination thereof. The image is formed on the retina by a predetermined indirect path selected from (z) optical reflective path and (U) electronic processing. Optionally, also a refracted image may also be created on the retina.

Abstract: An optical processor is presented for applying optical processing to a light field passing through a predetermined imaging lens unit. The optical processor comprises a pattern in the form of spaced apart regions of different optical properties. The pattern is configured to define a phase coder, and a dispersion profile coder. The phase coder affects profiles of Through Focus Modulation Transfer Function (TFMTF) for different wavelength components of the light field in accordance with a predetermined profile of an extended depth of focusing to be obtained by the imaging lens unit. The dispersion profile coder is configured in accordance with the imaging lens unit and the predetermined profile of the extended depth of focusing to provide a predetermined overlapping between said TFMTF profiles within said predetermined profile of the extended depth of focusing.

Abstract: The present invention provides copolymers made up of alkoxyalkyl methacrylate and/or alkoxyalkyl acrylate monomers in combination with one or more additional hydrophobic monomers. The copolymers may be used in the manufacture of intraocular lenses, including both the optic and haptic portions of the lenses. The present invention also provide methods for making intraocular lenses from the copolymers.

Abstract: High refractive index copolymers with reduced tack are disclosed. The copolymers, which are particularly suitable for use as ophthalmic device materials, comprise a benzhydryl methacrylate or benzhydryl methacrylate derivative monomer.

Abstract: An intraocular lens for providing vision to an animal or human subject has anterior and posterior sides. The lens includes an optic body, one or more haptics, and one or more marks. Each mark has four or more features disposed along an imaginary line when viewed from the anterior side and/or the posterior side. The mark(s) may be used as an aid in angularly aligning the lens during use.