Patents Represented by Attorney Paul L. Sabatine

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  • Dosage forms comprising polymers comprising different molecular weights
    Patent number: 5208037
    Abstract: A dosage form is disclosed comprising a wall surrounding a compartment, which comprises a first composition comprising a carboxymethylcellulose and a second composition comprising a higher molecular weigh carboxymethylcellulose. The first composition comprises a dosage amount of drug that delivers from the dosage form at a controlled rate over time.
    Type: Grant
    Filed: April 22, 1991
    Date of Patent: May 4, 1993
    Assignee: ALZA Corporation
    Inventors: Jeri D. Wright, Brian L. Barclay, David R. Swanson
  • Density element for ruminal delivery device
    Patent number: 5206024
    Abstract: A corrosion resistent density element for use in ruminal delivery devices which fragments upon contact with the blades in grinding machinery without damage to the blades. The density element has density of at least about 1.5 g/ml and a transverse rupture strength no greater than about 30,000 psi.
    Type: Grant
    Filed: December 24, 1991
    Date of Patent: April 27, 1993
    Assignee: Alza Corporation
    Inventors: John R. Peery, James B. Eckenhoff
  • Dosage form providing immediate therapy followed by prolonged therapy
    Patent number: 5204116
    Abstract: A dosage form is disclosed comprising a first layer and a second layer. The first layer provides immediate therapy and comprises a drug stereoisomer and the second layer provides prolonged therapy and comprises a drug racemate.
    Type: Grant
    Filed: May 1, 1991
    Date of Patent: April 20, 1993
    Assignee: Alza Corporation
    Inventors: David E. Edgren, Gurdish K. Bhatti, Judy A. Magruder
  • Improvement in pulsed drug therapy
    Patent number: 5200196
    Abstract: A dosage form comprising (1) an immediately available dose of a beneficial drug followed by a timed delayed dose of drug, or (2) a timed delayed dose of drug.
    Type: Grant
    Filed: January 11, 1991
    Date of Patent: April 6, 1993
    Assignee: ALZA Corporation
    Inventors: Atul D. Ayer, Felix Theeuwes, Patrick S. L. Wong
  • Contraceptive pill
    Patent number: 5200197
    Abstract: An osmotic device is disclosed comprising an exterior coat comprising an estrogenic and a progestogenic steroid that are delivered immediately as a contraceptive pair for fertility regulation in a female, and a compartment comprising an estrogenic steroid that is delivered at a controlled rate over a prolonged period of time for fertility regulation in a female.
    Type: Grant
    Filed: December 9, 1991
    Date of Patent: April 6, 1993
    Assignee: Alza Corporation
    Inventors: Jeri D. Wright, Jerry D. Childers, Brian L. Barclay, Patrick S.-L. Wong, Linda E. Atkinson
  • Process for improving dosage form delivery kinetics
    Patent number: 5200195
    Abstract: A dosage form is disclosed comprising means for lessening the tackiness and/or irritation of the components of the dosage form to mucosal tissue. The dosage form provides means for forming in the dosage form a floc comprising a drug, which floc, when delivered from the dosage form, lessens the tackiness and/or irritation of the mucosal tissue of a warm-blooded recipient.
    Type: Grant
    Filed: December 6, 1991
    Date of Patent: April 6, 1993
    Assignee: ALZA Corporation
    Inventors: Liang C. Dong, Michael H. Dealey, Terry L. Burkoth, Patrick S. L. Wong, Jerry D. Childers, Brian L. Barclay
  • Dosage form for treating central nervous system disorders
    Patent number: 5192550
    Abstract: A dosage form is disclosed comprising an anti-Parkinson's disease drug for administering to a patient in need of anti-Parkinson's disease therapy.
    Type: Grant
    Filed: March 5, 1992
    Date of Patent: March 9, 1993
    Assignee: ALZA Corporation
    Inventors: David E. Edgren, Howard A. Carpenter, Gurdish K. Bhatti, Atul D. Ayer
  • Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
    Patent number: 5190763
    Abstract: A dosage form is disclosed comprising an anti-Parkinson's disease drug for administering to a patient in need of anti-Parkinson's disease therapy.
    Type: Grant
    Filed: May 7, 1990
    Date of Patent: March 2, 1993
    Assignee: ALZA Corporation
    Inventors: David E. Edgren, Howard A. Carpenter, Gurdish K. Bhatti, Atul D. Ayer
  • Therapy delayed
    Patent number: 5190765
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: March 2, 1993
    Assignee: ALZA Corporation
    Inventors: Frank Jao, Patrick S. L. Wong, Hoa T. Huynh, Kathy McChesney, Pamela K. Wat
  • Nicardipine therapy
    Patent number: 5186942
    Abstract: A dosage form is disclosed comprising a member selected from the group consisting of nicardipine and its pharmaceutically acceptable salts for administering to a patient in need of cardio-vascular therapy.
    Type: Grant
    Filed: November 18, 1991
    Date of Patent: February 16, 1993
    Assignee: ALZA Corporation
    Inventors: Joseph C. Deters, David R. Swanson, Stephen C. DeRosa
  • Dosage form comprising succinimide drug for treating depressive disorders and composition comprising same
    Patent number: 5185158
    Abstract: A dosage form is provided for administering a drug of the formula ##STR1## to a patient to produce an anxiolytic benefit in the patient.
    Type: Grant
    Filed: February 27, 1992
    Date of Patent: February 9, 1993
    Assignee: ALZA Corporation
    Inventors: Atul Ayer, Dana Ridzon
  • Dosage form for delivering drug in short-time period
    Patent number: 5178867
    Abstract: The invention pertains to a dosage form for orally administering a drug in eight hours or less to the stomach and small intestine for a therapeutic result.
    Type: Grant
    Filed: August 19, 1991
    Date of Patent: January 12, 1993
    Assignee: Alza Corporation
    Inventors: George V. Guittard, Howard A. Carpenter, Ernest S. Quan, Patrick S. Wong, Lawrence G. Hamel
  • Dosage form for delivering drug to the intestine
    Patent number: 5178866
    Abstract: A drug delivery device is disclosed for delivering a drug to the intestine and the colon. The device comprises external means for delaying the delivery of drug in the stomach, and hydrophobic means for preventing the passage of fluid through the delay means.
    Type: Grant
    Filed: March 23, 1990
    Date of Patent: January 12, 1993
    Assignee: ALZA Corporation
    Inventors: Jeremy C. Wright, George V. Guittard
  • Antimicrobial device for urine drainage container
    Patent number: 5176665
    Abstract: The invention pertains to a delivery system comprising a biocide, with the delivery system designed and shaped for passage through the exit port of a urine container into the container.
    Type: Grant
    Filed: January 18, 1991
    Date of Patent: January 5, 1993
    Assignee: Alza Corporation
    Inventors: Tyler Watanabe, Su I. Yum, Eun S. Lee, Ivan W. Chin
  • Delivery system comprising fluid ingress and drug egress
    Patent number: 5174999
    Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
    Type: Grant
    Filed: April 20, 1990
    Date of Patent: December 29, 1992
    Assignee: ALZA Corporation
    Inventors: Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Peery
  • Antiemetic therapy
    Patent number: 5166145
    Abstract: A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.
    Type: Grant
    Filed: September 10, 1990
    Date of Patent: November 24, 1992
    Assignee: Alza Corporation
    Inventors: Francisco Jao, Hoa I. Huynh, Patrick S. L. Wong
  • Verapmil therapy
    Patent number: 5160744
    Abstract: A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: November 3, 1992
    Assignee: Alza Corporation
    Inventors: Frank Jao, Patrick S. Wong, Hoa T. Huynh, Kathy McChesney, Pamela K. Wat
  • Annealed composition for pharmaceutically acceptable drug
    Patent number: 5160743
    Abstract: A dosage form is disclosed comprising a coat that surrounds a drug. The coat comprises a subcoat and an overcoat thermally annealed to provide a single unit coat around the drug.
    Type: Grant
    Filed: January 28, 1991
    Date of Patent: November 3, 1992
    Assignee: Alza Corporation
    Inventors: David E. Edgren, Felix Theeuwes
  • Dosage form for time-varying patterns of drug delivery
    Patent number: 5156850
    Abstract: A dosage form is disclosed that comprises means inside the dosage form for providing a substantially drug-free interval before the dosage form delivers a drug from inside the dosage form. The dosage form in an embodiment comprises a drug on the exterior of the dosage form, which drug is available for immediate delivery.
    Type: Grant
    Filed: August 31, 1990
    Date of Patent: October 20, 1992
    Assignee: ALZA Corporation
    Inventors: Patrick S. Wong, Felix Theeuwes, Atul D. Ayer, Anthony L. Kuczynski
  • Delayed drug delivery device
    Patent number: 5141752
    Abstract: A dosage form comprising (1) an immediately available dose of a beneficial drug followed by a timed delayed dose of drug, or (2) a timed delayed dose of drug.
    Type: Grant
    Filed: July 25, 1991
    Date of Patent: August 25, 1992
    Assignee: Alza Corporation
    Inventors: Atul D. Ayer, Felix Theeuwes, Patrick S. L. Wong