Patents Represented by Attorney Paul L. Sabatine

Find this attorney in the Justia Lawyer Directory

  • Delivery system for administering agent to ruminants and swine
    Patent number: 5135523
    Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
    Type: Grant
    Filed: April 20, 1990
    Date of Patent: August 4, 1992
    Assignee: ALZA Corporation
    Inventors: Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Peery
  • Dosage form for Parkinson's disease, spasticity and muscle spasms
    Patent number: 5128145
    Abstract: A dosage form is disclosed comprising a drug and a maltodextrin polymer for administering to a patient a drug in need of therapy.
    Type: Grant
    Filed: August 2, 1991
    Date of Patent: July 7, 1992
    Assignee: Alza Corporation
    Inventors: David E. Edgren, Gurdish K. Bhatti, Howard A. Carpenter
  • Dispenser comprising ionophore
    Patent number: 5126142
    Abstract: A dispenser is disclosed for delivering a beneficial ionophore to an animal. The dispenser comprises (1) a semipermeable housing defining an internal space, (2) at least one composition comprising an ionophore and a pharmaceutically acceptable carrier in the space, (3) an expandable hydrophilic composition in the space, (4) a dense member in the space, and (5) at least one exit passageway in the housing for delivering the ionophore from the dispenser.
    Type: Grant
    Filed: January 11, 1991
    Date of Patent: June 30, 1992
    Assignee: ALZA Corporation
    Inventors: Atul D. Ayer, Terry L. Burkoth, Anthony L. Kuczynski, Joseph C. Deters
  • Delivery system comprising means for delivering agent to livestock
    Patent number: 5110596
    Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
    Type: Grant
    Filed: April 20, 1990
    Date of Patent: May 5, 1992
    Assignee: Alza Corporation
    Inventors: Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Peery
  • Fluid receiving receptacle comprising biocide delivery system contacting outside of receptacle
    Patent number: 5104390
    Abstract: A patient-care apparatus comprising a container for receiving a biological fluid, and a delivery device on the outside of the container, which device comprises a biocide that is released to the container for preventing the multiplication of and/or eliminating the presence of unwanted pathogens in the container.
    Type: Grant
    Filed: April 2, 1990
    Date of Patent: April 14, 1992
    Assignee: ALZA Corporation
    Inventors: Su I. Yum, Felix Theeuwes
  • Osmotic, oral dosage form for fertility control
    Patent number: 5098714
    Abstract: An osmotic device is disclosed comprising an exterior coat comprising an estrogenic and a progestogenic steroid that are delivered immediately as a contraceptive pair for fertility regulation in a female, and a compartment comprising an estrogenic steroid that is delivered at a controlled rate over a prolonged period of time for fertility regulation in a female.
    Type: Grant
    Filed: November 16, 1989
    Date of Patent: March 24, 1992
    Assignee: ALZA Corporation
    Inventors: Jeri D. Wright, Jerry D. Childers, Brian L. Barclay, Patrick S. Wong, Linda E. Atkinson
  • Method of administering a ruminant dispensing device comprising density member dispersed in hydrogel member
    Patent number: 5098425
    Abstract: A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) an expandable composition comprising a dense member in the space, (3) a composition comprising a beneficial agent and a non-toxic heat responsive carrier in the space,and (4) a passageway in the housing for delivering the beneficial agent from the dispensing device.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: March 24, 1992
    Assignee: ALZA Corporation
    Inventor: James B. Eckenhoff
  • Dosage form for administering calcium antagonist nicardipine
    Patent number: 5096716
    Abstract: A dosage form is disclosed comprising a member selected from the group consisting of nicardipine and its pharmaceutically acceptable salts for administering to a patient in need of cardiovascular therapy.
    Type: Grant
    Filed: May 18, 1990
    Date of Patent: March 17, 1992
    Assignee: ALZA Corporation
    Inventors: Joseph C. Deters, David R. Swanson, Stephen C. DeRosa
  • Delivery system for administration blood-glucose lowering drug
    Patent number: 5091190
    Abstract: A dosage form is disclosed comprising the antidiabetic drug glipizide for administering to a patient in need of glipizide therapy.
    Type: Grant
    Filed: February 8, 1991
    Date of Patent: February 25, 1992
    Assignee: ALZA Corporation
    Inventors: Anthony L. Kuczynski, Atul D. Ayer, Patrick S. Wong
  • Controlled-release system with constant pushing source
    Patent number: 5082668
    Abstract: A device is disclosed comprising a wall that surrounds a compartment. The compartment comprises a beneficial agent composition and a push composition. A passageway in the wall connects the compartment with the exterior of the device for delivering the beneficial agent at a rate governed, in combination, by the wall, the beneficial agent composition and the push composition through the passageway of the device over time.
    Type: Grant
    Filed: October 9, 1990
    Date of Patent: January 21, 1992
    Assignee: Alza Corporation
    Inventors: Patrick S. L. Wong, Brian L. Barclay, Joseph C. Deters, Felix Theeuwes
  • Nicotine packaging materials
    Patent number: 5077104
    Abstract: The invention herein pertains to methods and materials for producing a nicotine maintenance pouch. Laminates comprising a nicotine barrier layer and a nicotine degradation agent barrier layer are disclosed. In a preferred embodiment, the nicotine barrier layer comprises a nitrile rubber modified acrylonitrile-methyl acrylate copolymer. An especially preferred nicotine barrier material comprises, by weight percent, 75% acrylonitrile, and 25% methyl acrylate with 10% butadiene (AN-MA/B). The nicotine degradation agent barrier layer is preferably aluminum foil. In an especially preferred embodiment, the laminate comprises a layer of AN-MA/B adhered to a layer of aluminum foil, which in turn is adhered to a layer of paper stock.Pouches comprising a self-sealed nicotine barrier layer and a nicotine degradation agent barrier layer are disclosed. These pouches are preferably formed from the laminates above.
    Type: Grant
    Filed: December 21, 1989
    Date of Patent: December 31, 1991
    Assignee: Alza Corporation
    Inventors: James A. Hunt, James L. Osborne, John T. Dunn, Melinda K. Nelson, Nathan Roth
  • Method and apparatus for forming a hole in a drug dispensing device
    Patent number: 5071607
    Abstract: A press is provided for simultaneously pressing and piercing an object. The piercing means moves from a sheathed to unsheathed position in response to compressive pressure. The piercing means are normally biased in the sheathed position by a bias means. Methods and apparatus for piercing an object are disclosed. The press can be used to produce a pierced dispensing device having a compression coating by (a) charging to a die mold a quantity of powder to be compressed; (b) delivering to the die mold an unpierced dispensing device core; (c) charging to the die mold an additional quantity of powder to be compressed; and (d) substantially simultaneously (i) compressing the elements within the die mold to produce a compression coating, and (ii) piercing the compression coating. The compression coating can comprise, for example, a loading dose or a semipermeable membrane.
    Type: Grant
    Filed: January 31, 1990
    Date of Patent: December 10, 1991
    Assignee: ALZA Corporatino
    Inventors: Atul D. Ayer, Hans H. Balkie
  • Intravenous medication
    Patent number: 5069671
    Abstract: A parenteral delivery system and a formulation chamber are disclosed for administering a beneficial agent. The parenteral delivery system comprises a drip chamber and a formulation chamber. The formulation chamber comprises a wall surrounding an internal space and it has an inlet for admitting a liquid into the formulation chamber and an outlet for letting an agent formulation leave the formulation chamber. The chamber houses an agent delivery system for releasing a beneficial agent into a liquid that enters the chamber.
    Type: Grant
    Filed: June 23, 1988
    Date of Patent: December 3, 1991
    Assignee: ALZA Corporation
    Inventor: Felix Theeuwes
  • Delivery system comprising biocompatible beneficial agent formulation
    Patent number: 5059423
    Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
    Type: Grant
    Filed: April 23, 1990
    Date of Patent: October 22, 1991
    Assignee: Alza Corporation
    Inventors: Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Peery
  • Dosage form comprising drug and maltodextrin
    Patent number: 5057321
    Abstract: A dosage form is disclosed comprising a drug and a maltodextrin polymer for administering to a patient a drug in need of therapy.
    Type: Grant
    Filed: June 13, 1990
    Date of Patent: October 15, 1991
    Assignee: ALZA Corporation
    Inventors: David E. Edgren, Gurdish K. Bhatti, Howard A. Carpenter
  • Delivery system for beneficial agent over a broad range of rates
    Patent number: 5057318
    Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
    Type: Grant
    Filed: April 20, 1990
    Date of Patent: October 15, 1991
    Assignee: ALZA Corporation
    Inventors: Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Perry
  • Long-term delivery device including loading dose
    Patent number: 5045082
    Abstract: The invention provides a long-term dispensing device comprising a first agent delivery means for short-term and continuous delivery of agent, retained together with a second agent delivery means capable of long-term and continuous delivery of agent. The combination of first and second agent delivery means provides a device in which a substantially constant dose of beneficial agent is delivered to the environment of use over time. A rapid delivery of beneficial agent is followed by continuous and prolonged delivery of agent.
    Type: Grant
    Filed: January 10, 1990
    Date of Patent: September 3, 1991
    Assignee: Alza Corporation
    Inventors: Atul D. Ayer, James B. Eckenhoff, Jeremy C. Wright, Anthony L. Kuczynski
  • Delivery system comprising two sections for delivering somatotropin
    Patent number: 5037420
    Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
    Type: Grant
    Filed: April 20, 1990
    Date of Patent: August 6, 1991
    Assignee: ALZA Corporation
    Inventors: Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Peery
  • Dosage form for delivering soluble or insoluble drugs
    Patent number: 5035897
    Abstract: A dosage form is disclosed comprising granule means for delivering soluble to insoluble drug to a warm-blooded animal.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: July 30, 1991
    Assignee: Alza Corporation
    Inventors: Atul D. Ayer, Anthony L. Kuczynski, Patrick S. Wong
  • Dispenser for increasing feed conversion of hog
    Patent number: 5034229
    Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
    Type: Grant
    Filed: December 13, 1988
    Date of Patent: July 23, 1991
    Assignee: ALZA Corporation
    Inventors: Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Peery