Patents Represented by Attorney Robert L. Stone
  • Patent number: 4122164
    Abstract: Dental cream suitable for use in an unlined aluminum container comprising between about 35% and 60% of abrasive containing alumina as the major abrasive component and as agents to render the dental cream compatible with an unlined aluminum container, calcium carbonate present as minor abrasive component in amount of at least about 1% of the dental cream and a dissolved or dispersed silicate present in amount of about 0.05%-0.25%. The composition also desirably contains a water-soluble monofluorophosphate salt in amount which provides 0.01-1% fluoride in the dental cream and when the dental cream contains the monofluorophosphate salt and more than about 5% calcium carbonate, an alkali metal tripolyphosphate in an amount up to about 1.5% is also present.
    Type: Grant
    Filed: August 15, 1977
    Date of Patent: October 24, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Robert Lee Mitchell, William John Chung
  • Patent number: 4118471
    Abstract: A dentifrice which is stable in an unlined aluminum tube comprising alpha-alumina trihydrate polishing agent and which has a pH of about 6.5-8.0, which dentifrice contains an acidifying agent consisting essentially of saccharin acid.
    Type: Grant
    Filed: June 9, 1977
    Date of Patent: October 3, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Philip Pensak
  • Patent number: 4118476
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces straining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a phosphono polycarboxylic acid compound, such as 1-phosphonoethane-1,2-dicarboxylic acid and salts thereof.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: October 3, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Hollandra P. Niles
  • Patent number: 4118472
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a quaternary aminoalkylene phosphonic acid, such as N-methyl aminotri(methylene phosphonic acid) and salts thereof.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: October 3, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Hollandra P. Niles
  • Patent number: 4118474
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is phosphonoacetic acid or salts thereof.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: October 3, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Hollandra P. Niles
  • Patent number: 4118473
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is an N-methylene phosphonate compound, such as iminodiacetic N-methylene phosphonic acid and salts thereof.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: October 3, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Hollandra P. Niles
  • Patent number: 4118475
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a diphosphono pyrrolidone compound, such as pyrrolidone-5,5-diphosphonic acid, or salts thereof.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: October 3, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Hollandra P. Niles
  • Patent number: 4115546
    Abstract: Oral compositions containing dextranase and a stabilizer/activator selected from the group consisting of manganeous ions, calcium ions, magnesium ions, and mixtures thereof.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: September 19, 1978
    Assignee: Colgate Palmolive Company
    Inventors: James David Vidra, Julius Harvey Nachtigal
  • Patent number: 4110429
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride are typical examples of antibacterial agents. The antistain additive is a water soluble oligomer of the formula ##STR1## wherein M is a water soluble orally acceptable cation;R.sub.1, r.sub.2, r.sub.3 and R.sub.4 are independently H, methyl or ethyl;Y is at least one hydrophilic member of the group consisting of --COOM.sub.1, --CONH.sub.2, and --CH.sub.2 OH;X is at least one hydrophobic member of the group consisting of --CN, --COOR, --COOR.sub.5 OR, --CONHR, --COONHR.sub.5 COR, and --OOCR;M.sub.1 is H or M;R is C.sub.1-8 alkyl;R.sub.5 is C.sub.1-4 alkylene;a is 0-7; anda+b is about 4-15.
    Type: Grant
    Filed: December 30, 1976
    Date of Patent: August 29, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Stuart D. Friedman
  • Patent number: 4108980
    Abstract: A process of supplying fluoride to teeth comprising applying to the teeth a source of fluoride ions and an orthophosphoric acid solution having a pH of about 3-4, then neutralizing the pH to about 7 with an aqueous neutralizing solution containing calcium ions and phosphate ions, wherein there is present about a stoichiometric amount of the phosphate ions relative to the calcium ions, the neutralizing solution having a pH of about 7.
    Type: Grant
    Filed: March 4, 1977
    Date of Patent: August 22, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Edward John Duff
  • Patent number: 4105758
    Abstract: Oral compositions containing an anticalculus agent selected from the group consisting of compounds having the following structural formulas: ##STR1## wherein X, X', Y, and Y' are selected from the group consisting of H, OH, SO.sub.3 Na, and CH.sub.2 N(CH.sub.2 COOH).sub.2 and additionally wherein at least two of the substituents X, X', Y, and Y' must be hydroxyls, and at least one of the further of said substituents must be OH, SO.sub.3 Na, or CH.sub.2 N (CH.sub.2 COOH).sub.2. The preferred anthraquinoid derivatives are Alizarin red S monohydrate, Alizarin complexone dihydrate, purpurin, and purpurin sulfonate.
    Type: Grant
    Filed: December 27, 1976
    Date of Patent: August 8, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Ronald S. Schreiber
  • Patent number: 4105759
    Abstract: Novel bis long chain (C.sub.8 - C.sub.18) amine monofluorophosphates, particularly useful as substantive, slow release fluoride agents for anti-caries prophylaxis; the process of preparing said amine monofluorophosphates; and compositions containing an effective amount of said fluoride agent admixed with a pharmaceutical carrier, more particularly an oral composition.
    Type: Grant
    Filed: March 28, 1977
    Date of Patent: August 8, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Ronald S. Schreiber, Edward J. Duff
  • Patent number: 4102993
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis-(phosphonomethylene) amine acid and salts thereof.
    Type: Grant
    Filed: April 25, 1977
    Date of Patent: July 25, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 4102994
    Abstract: Novel quaternary ammonium compounds containing two large aliphatic or alicyclic groups, one of which is separated from the quaternary nitrogen by an amide linkage.
    Type: Grant
    Filed: May 31, 1977
    Date of Patent: July 25, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Robert Andrew Bauman
  • Patent number: 4100270
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis-(phosphonomethylene) amine acid and salts thereof.
    Type: Grant
    Filed: April 25, 1977
    Date of Patent: July 11, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 4098880
    Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis(phosphonomethylene) amine acid and salts thereof.
    Type: Grant
    Filed: April 25, 1977
    Date of Patent: July 4, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 4098435
    Abstract: A stabilized and extrudable paste or gel dentifrice comprises two dentifrice portions, each of which includes a component which is chemically reactive with the other such component in the other portion, with the portions being maintained separate from each other in a dispensing container from which they are dispensable together through a closable opening therein in response to pressure. One of the reactive components is an alkali metal fluorine-containing salt such as sodium fluoride or sodium monofluorophosphate, used for its effect in hardening tooth enamel, and the other is a water insoluble calcium salt, such as dicalcium phosphate, tricalcium phosphate or calcium carbonate, used as a polishing agent. The dentifrice portions are preferably separated by an extrudable material, such as a polyhydric alcohol-water gel of a gum, such as sodium carboxymethyl cellulose. Also within the invention is a method for the manufacture of the mentioned dentifrice.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: July 4, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Hendrik Frans Weyn
  • Patent number: 4098878
    Abstract: Dentifrices containing milled alpha-alumina trihydrate which has been surface-treated with a higher fatty acid.
    Type: Grant
    Filed: October 23, 1975
    Date of Patent: July 4, 1978
    Assignee: Colgate-Palmolive Company
    Inventors: Eric Baines, Peter Platt, Kenneth Tomlinson
  • Patent number: 4097600
    Abstract: Quaternary ammonium carbamate, thiocarbamate, dithiocarbamate and carbamide compounds. Typical examples are?C.sub.4 H.sub.9 NHCOO(CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.2 C.sub.12 H.sub.25 !Br.sup.-?C.sub.4 H.sub.9 NHCSO(CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.2 C.sub.12 H.sub.25 !Br.sup.-?CH.sub.3 NHCSS(CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.2 C.sub.12 H.sub.25 !Br.sup.-?C.sub.2 H.sub.5 NHCONH(CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.2 C.sub.12 H.sub.25 !Br.sup.
    Type: Grant
    Filed: November 12, 1976
    Date of Patent: June 27, 1978
    Assignee: Colgate Palmolive Company
    Inventor: Robert Andrew Bauman
  • Patent number: 4082756
    Abstract: Quaternary ammonium carbamate, thiocarbamate, dithiocarbamate and carbamide compounds. Typical examples are[C.sub.4 H.sub.9 NHCOO(CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.2 C.sub.12 H.sub.25 ]Br.sup.-[C.sub.4 H.sub.9 NHCSO(CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.2 C.sub.12 H.sub.25 ]Br.sup.-[CH.sub.3 NHCSS(CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.2 C.sub.12 H.sub.25 ]Br.sup.-[C.sub.2 H.sub.5 NHCONH(CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.2 C.sub.12 H.sub.25 ]Br.sup.
    Type: Grant
    Filed: February 20, 1976
    Date of Patent: April 4, 1978
    Assignee: Colgate-Palmolive Company
    Inventor: Robert Andrew Bauman