Abstract: Dental cream suitable for use in an unlined aluminum container comprising between about 35% and 60% of abrasive containing alumina as the major abrasive component and as agents to render the dental cream compatible with an unlined aluminum container, calcium carbonate present as minor abrasive component in amount of at least about 1% of the dental cream and a dissolved or dispersed silicate present in amount of about 0.05%-0.25%. The composition also desirably contains a water-soluble monofluorophosphate salt in amount which provides 0.01-1% fluoride in the dental cream and when the dental cream contains the monofluorophosphate salt and more than about 5% calcium carbonate, an alkali metal tripolyphosphate in an amount up to about 1.5% is also present.
Type:
Grant
Filed:
August 15, 1977
Date of Patent:
October 24, 1978
Assignee:
Colgate-Palmolive Company
Inventors:
Robert Lee Mitchell, William John Chung
Abstract: A dentifrice which is stable in an unlined aluminum tube comprising alpha-alumina trihydrate polishing agent and which has a pH of about 6.5-8.0, which dentifrice contains an acidifying agent consisting essentially of saccharin acid.
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces straining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a phosphono polycarboxylic acid compound, such as 1-phosphonoethane-1,2-dicarboxylic acid and salts thereof.
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a quaternary aminoalkylene phosphonic acid, such as N-methyl aminotri(methylene phosphonic acid) and salts thereof.
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is phosphonoacetic acid or salts thereof.
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is an N-methylene phosphonate compound, such as iminodiacetic N-methylene phosphonic acid and salts thereof.
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a diphosphono pyrrolidone compound, such as pyrrolidone-5,5-diphosphonic acid, or salts thereof.
Abstract: Oral compositions containing dextranase and a stabilizer/activator selected from the group consisting of manganeous ions, calcium ions, magnesium ions, and mixtures thereof.
Type:
Grant
Filed:
August 16, 1976
Date of Patent:
September 19, 1978
Assignee:
Colgate Palmolive Company
Inventors:
James David Vidra, Julius Harvey Nachtigal
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride are typical examples of antibacterial agents. The antistain additive is a water soluble oligomer of the formula ##STR1## wherein M is a water soluble orally acceptable cation;R.sub.1, r.sub.2, r.sub.3 and R.sub.4 are independently H, methyl or ethyl;Y is at least one hydrophilic member of the group consisting of --COOM.sub.1, --CONH.sub.2, and --CH.sub.2 OH;X is at least one hydrophobic member of the group consisting of --CN, --COOR, --COOR.sub.5 OR, --CONHR, --COONHR.sub.5 COR, and --OOCR;M.sub.1 is H or M;R is C.sub.1-8 alkyl;R.sub.5 is C.sub.1-4 alkylene;a is 0-7; anda+b is about 4-15.
Abstract: A process of supplying fluoride to teeth comprising applying to the teeth a source of fluoride ions and an orthophosphoric acid solution having a pH of about 3-4, then neutralizing the pH to about 7 with an aqueous neutralizing solution containing calcium ions and phosphate ions, wherein there is present about a stoichiometric amount of the phosphate ions relative to the calcium ions, the neutralizing solution having a pH of about 7.
Abstract: Oral compositions containing an anticalculus agent selected from the group consisting of compounds having the following structural formulas: ##STR1## wherein X, X', Y, and Y' are selected from the group consisting of H, OH, SO.sub.3 Na, and CH.sub.2 N(CH.sub.2 COOH).sub.2 and additionally wherein at least two of the substituents X, X', Y, and Y' must be hydroxyls, and at least one of the further of said substituents must be OH, SO.sub.3 Na, or CH.sub.2 N (CH.sub.2 COOH).sub.2. The preferred anthraquinoid derivatives are Alizarin red S monohydrate, Alizarin complexone dihydrate, purpurin, and purpurin sulfonate.
Abstract: Novel bis long chain (C.sub.8 - C.sub.18) amine monofluorophosphates, particularly useful as substantive, slow release fluoride agents for anti-caries prophylaxis; the process of preparing said amine monofluorophosphates; and compositions containing an effective amount of said fluoride agent admixed with a pharmaceutical carrier, more particularly an oral composition.
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis-(phosphonomethylene) amine acid and salts thereof.
Abstract: Novel quaternary ammonium compounds containing two large aliphatic or alicyclic groups, one of which is separated from the quaternary nitrogen by an amide linkage.
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis-(phosphonomethylene) amine acid and salts thereof.
Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis(phosphonomethylene) amine acid and salts thereof.
Abstract: A stabilized and extrudable paste or gel dentifrice comprises two dentifrice portions, each of which includes a component which is chemically reactive with the other such component in the other portion, with the portions being maintained separate from each other in a dispensing container from which they are dispensable together through a closable opening therein in response to pressure. One of the reactive components is an alkali metal fluorine-containing salt such as sodium fluoride or sodium monofluorophosphate, used for its effect in hardening tooth enamel, and the other is a water insoluble calcium salt, such as dicalcium phosphate, tricalcium phosphate or calcium carbonate, used as a polishing agent. The dentifrice portions are preferably separated by an extrudable material, such as a polyhydric alcohol-water gel of a gum, such as sodium carboxymethyl cellulose. Also within the invention is a method for the manufacture of the mentioned dentifrice.