Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a bis(o-carboxyphenyl)ester of a C.sub.2-8 aliphatic dicarboxylic acid such as bis(o-carboxyphenyl)succinate.

Abstract: Dental cream suitable for use in an unlined aluminum container comprising between about 35 and 60% of abrasive containing alumina as the major abrasive component and as agents to render the dental cream compatible with an unlined aluminum container, calcium carbonate present as minor abrasive component in amount of at least about 1% of the dental cream and a dissolved or dispersed silicate present in amount of about 0.05-0.25%. The composition also desirably contains a water-soluble monofluorophosphate salt in amount which provides 0.01-1% fluoride in the dental cream and when the dental cream contains the monofluorophosphate salt and more than about 5% calcium carbonate, an alkali metal tripolyphosphate in an amount up to about 1.5% is also present.

Abstract: Dentifrices containing flat flakes of alpha-alumina.

Abstract: A method for manufacturing a visually clear dentifrice from a substantially water-insoluble polishing agent having a refractive index of about 1.44 to 1.48, such as a colloidal silica, an amorphous silicic anhydride or an amorphous complex aluminosilicate, a synthetic inorganic complex silicate clay gelling agent of the formula[Si.sub.8 Mg.sub.5.1 Li.sub.0.6 H.sub.7.6 O.sub.24 ].sup.0.6.spsp.- Na .sup.+.sub.0.6 ,and a vehicle which includes water, sorbitol and glycerine, which method requires initial mixing of the gelling agent with a sorbitol solution in water to produce a clear gel, followed by admixing glycerine with said clear gel. The described manufacturing method results in quicker production of clear gels of the present formulations than do corresponding methods in which the gelling agent is initially mixed with glycerine or glycerine-containing mixtures.

Abstract: Dentifrice speckles of substantially uniform shape and size are made by agitating the material of such speckles (binder plus dentifrice component) in a liquid dispersing medium at a temperature at which the binder is liquid but undissolved and unemulsified in the dispersing medium, and cooling the dispersion to a temperature below the solidification point of the speckling material so as to solidify it into speckles of desired size. Such speckles may be separated from the dispersing medium or may remain in it and be utilized with it. Preferably the speckles are incorporated in dentifrices and contain dentifrice components desirably maintained separate from the rest of the dentifrice. Also included within the invention described are the speckles and dentifrices containing them.

Abstract: Dentifrice speckles of substantially uniform shape and size are made by agitating the material of such speckles (binder plus dentifrice component) in a liquid dispersing medium at temperature at which the binder is liquid but undissolved and unemulsified in the dispersing medium, and cooling the dispersion to a temperature below the solidification point of the speckling material so as to solidify it into speckles of desired size. Such speckles may be separated from the dispersing medium or may remain in it and be utilized with it. Preferably the speckles are incorporated in dentifrices and contain dentifrice components desirably maintained separate from the rest of the dentifrice. Also included within the invention described are the speckles and dentifrices containing them.

Abstract: Extrudible visually clear gel dentifrice containing distributed therein visible bubbles of gas, said dentifrice having a vehicle of viscosity sufficient to maintain the bubbles suspended therein.

Abstract: Dentifrices containing ground crystals of alpha-alumina having a mean ultimate particle size of about 1 to 2 microns. Typically, the size is that essentially 100% are below 10 microns; about 95% are below 5 microns; about 85% are below 3 microns; about 75% are below 2 microns; about 25% are below 1 micron; and about 5% are below 0.5 microns.

Abstract: Novel dibiguanides containing an ester substituent on the terminal phenyl radical and free of the presence of, or the tendency to form, toxic substances; the process of preparing said dibiguanides, and compositions containing an effective antimicrobial amount of said dibiguanides admixed with a pharmaceutical carrier.

Abstract: Preparation of a dentifrice composition containing an insolubilized salt of 1,6-di-(p-chlorophenyl biguanido) hexane antimicrobial agent such as the disarcosinate monomeric salt or monofluorophosphate polymeric salt. The insolubilized salt may be pre-formed or formed in situ in the dentifrice composition. The insolubilized material is antimicrobially effective and provides desirable cosmetic effect.

Abstract: Dental preparations containing materials having calcium and phosphate components are described. Such materials are typically fluorapatite, fluorohydroxyapatite, hydroxyapatite prepared by alternately changing the pH from about 7 to about 4 to about 7 several times, including such materials which have incorporated therein ions such as monofluorophosphate and carbonate or divalent ions such as zinc or fluoranions of a metal such as zinc, e.g. ZnF.sub.4.sup.-2.

Abstract: Novel quaternary ammonium compounds containing two large aliphatic or alicyclic groups, one of which is separated from the quaternary nitrogen by an amide linkage.

Abstract: Dental cream comprising between about 35 and 60% by weight of abrasive consisting essentially of calcium carbonate and alumina, with the alumina at least about 0.05% by weight of the dental cream and in an amount not greater than the calcium carbonate. The dental cream also contains a water-soluble monofluorophosphate salt in an amount which provides about 0.01-1% by weight fluoride in said dental cream and about 0.1-1.5% by weight of an alkali metal tripolyphosphate as an agent to improve the ability of the dental cream to retain monofluorophosphate as fluoride. The dental cream may also contain 0.025-0.25% by weight of a dissolved or dispersed silicate.

Abstract: An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis-(phosphonomethylene) amine acid and salts thereof.

Abstract: Dentifrice possessing enhanced cleaning and polishing characteristics containing as the essential cleaning and polishing agent calcium meta silicate.

Abstract: Quaternary ammonium carbamate, thiocarbamate, dithiocarbamate and carbamide compounds. Typical examples are[C.sub.4 H.sub.9 NHCOO(CH.sub.2).sub.2 N.sup.+(CH.sub.3).sub.2 C.sub.12 H.sub.25 ]Br.sup.-[C.sub.4 H.sub.9 NHCSO(CH.sub.2).sub.2 N.sup.+(CH.sub.3).sub.2 C.sub.12 H.sub.25 ]Br.sup.-[CH.sub.3 NHCSS(CH.sub.2).sub.2 N.sup.+(CH.sub.3).sub.2 C.sub.12 H.sub.25 ]Br.sup.-[C.sub.2 H.sub.5 NHCONH(CH.sub.2).sub.2 N.sup.+(CH.sub.3).sub.2 C.sub.12 H.sub.25 ]Br.sup.

Abstract: An oral preparation comprising a dentally acceptable oral vehicle and dispersed therein a cationic antibacterial agent in amount of about 0.01-5% by weight based on the cationic portion thereof and about 0.05-5% by weight of an anionic phosphate ester surface active agent comprising a mixture of monoester of the formula ##STR1## wherein R is an alkyl group of 10-20 carbon atoms, n an integer from 1-6 and M is selected from the group consisting of hydrogen, alkali metal and ammonium, said oral preparation having a pH of at least 6.

Abstract: Visually clear dentifrice comprising a water-insoluble aluminosilicate sodium salt complex in which the proportion of alumina is up to 3.3% by weight and in which the mole ratio of silica to alumina is at least about 45:1, as a polishing agent having a refractive index of about 1.44-1.47 and a gel vehicle for said polishing agent having about the same refractive index as said polishing agent, said polishing agent being substantially invisible in said gel vehicle.