Patents Assigned to Advanced Cardiovascular Systems
  • Stent mandrel fixture and method for reducing coating defects
    Patent number: 7776381
    Abstract: A stent mandrel fixture for supporting a stent during the application of a coating substance is provided.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: August 17, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Fuh-Wei Tang, Syed F A Hossainy, Dorie M. Happ, Ty Hu
  • Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
    Patent number: 7776991
    Abstract: The disclosure contains a medical article comprising a polymer containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid.
    Type: Grant
    Filed: June 19, 2009
    Date of Patent: August 17, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Yiwen Tang
  • Biocompatible coating for implantable medical devices
    Patent number: 7776926
    Abstract: A random or a block copolymer which includes at least one biologically compatible structural moiety and at least one biologically active moiety is disclosed. The random or block copolymer can be used for fabricating a coating for an implantable medical device such as a stent.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: August 17, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Charles D. Claude, Syed F. A. Hossainy, Eugene T. Michal
  • Coating abluminal surfaces of stents and other implantable medical devices
    Patent number: 7770536
    Abstract: A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces.
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: August 10, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yung Ming Chen, Jeff H. Smith, Celenia Gutierrez
  • Balloon catheter having a flexible distal end
    Patent number: 7771449
    Abstract: A catheter having an elongated shaft with a proximal end, a distal end, and at least one lumen, and a distal portion of the shaft being at least in part within an outer sheath having a wedge-shaped distal end. In one embodiment, the outer sheath around the distal end of the shaft is the distal skirt section of the balloon. In an alternative embodiment, the outer sheath is a sleeve member having at least a portion located distal to the distal end of the balloon.
    Type: Grant
    Filed: October 24, 2006
    Date of Patent: August 10, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jacky G. Duchamp, Misty Lynn Gervais, Teresita Baerga
  • Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
    Patent number: 7772359
    Abstract: This disclosure provides a method device and a method of forming the medical device. The medical device comprises a coating comprising a polymer. The polymer comprises at least two different blocks, at least one L1 block with the formula and at least one L2 block with the formula Medical devices comprising these polymers, mixtures of these polymers with therapeutic agents, and methods of making these polymers and mixtures are within the scope of this disclosure.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: August 10, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen D. Pacetti
  • Apparatus and process for electrolytic removal of material from a medical device
    Patent number: 7771581
    Abstract: An apparatus and process is disclosed for the electrolytic removal of metal from a device, such as a medical device. More particularly, the apparatus of the invention includes a mandrel having slots or openings therein to expose portions of a metallic device, such as a stent, to an electrolytic solution to remove metal from the exposed portion.
    Type: Grant
    Filed: May 17, 2005
    Date of Patent: August 10, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Joseph R. Callol, Karim Said Osman, Napoleon L. Caliguiran, Rommel C. Lumauig
  • COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME
    Publication number: 20100198343
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME
    Publication number: 20100198342
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • Coating for Implantable Devices and a Method of Forming the Same
    Publication number: 20100198340
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME
    Publication number: 20100198341
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • Coating for Implantable Devices and a Method of Forming the Same
    Publication number: 20100198339
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: August 5, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • Polymers of fluorinated monomers and hydrophilic monomers
    Patent number: 7766884
    Abstract: A polymer blend that contains a polymer of fluorinated monomers and another biocompatible polymer. The polymer blend can form a coating on a medical device. The medical device can be used for treat, prevent or ameliorate a medical condition.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: August 3, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen Dirk Pacetti
  • Method of regulating temperature of a composition for coating implantable medical devices
    Patent number: 7763308
    Abstract: An applicator for applying a coating substance to an implantable medical device, such as a stent, is provided. The applicator comprises a nozzle and a temperature controller in communication with the nozzle for adjusting the temperature of the coating substance. A method of using the applicator is also provided.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: July 27, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yung-Ming Chen, Charles R. Bobson, John F. LoPrete
  • Method of crimping a polymeric stent
    Patent number: 7761968
    Abstract: A method of crimping a stent to a support element is disclosed, the method comprising: positioning a polymeric stent around a support element; heating the stent, wherein the heated stent is above ambient temperature; and allowing the heated stent to radially contract onto the support element, wherein the heated stent radially contracts at least partially due to heating the stent.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: July 27, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, Patrick Wu
  • Stent Coating Method And Apparatus
    Publication number: 20100183799
    Abstract: An apparatus includes a mandrel for supporting a stent during a composition deposition process. The mandrel includes an elongated body for insertion into a longitudinal bore of a stent. The body comprises carbide.
    Type: Application
    Filed: March 26, 2010
    Publication date: July 22, 2010
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Jason Van Sciver, Greg Teaby, Phil Foreman, Manish Gada
  • Biocompatible polyacrylate compositions for medical applications
    Patent number: 7758880
    Abstract: A composition is disclosed comprising a structural component comprising linear acrylic homopolymers or linear acrylic copolymers and a biobeneficial component comprising copolymers having an acrylate moiety and a biobeneficial moiety.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: July 20, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Syed F. A. Hossainy
  • Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
    Patent number: 7758881
    Abstract: Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-inflammatory agent such as clobetasol are provided.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: July 20, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen Dugan
  • Radio frequency identification monitoring of stents
    Patent number: 7757543
    Abstract: A method and system of monitoring environmental exposure of stents using radiofrequency identification is disclosed.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: July 20, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Abigail Freeman, David C. Gale, Bin Huang, Daniel Castro
  • Stent and catheter assembly and method for treating bifurcations
    Patent number: 7753950
    Abstract: An apparatus and method is provided for stenting bifurcated vessels. A proximal angled stent is configured for implanting in a side-branch vessel wherein the proximal angled stent has an angulated portion that corresponds to the angle formed by the intersection of the side-branch vessel and the main vessel so that all portions of the side-branch vessel at the bifurcation are covered by the proximal angled stent. A main-vessel stent is provided for implanting in the main vessel, wherein the main-vessel stent has an aperture or stent cell that aligns with the opening to the side-branch vessel to permit unobstructed blood flow between the main vessel and the side-branch vessel. Side-branch and main-vessel catheter assemblies are advanced over a pair of guide wires for delivering, appropriately orienting, and implanting the proximal angled stent and the apertured stent.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: July 13, 2010
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: W. Stan Wilson, Kevin M. Mauch