Patents Assigned to Advanced Cardiovascular Systems
  • Intravascular stent
    Patent number: 7534258
    Abstract: The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since the peaks that are adjacent the curved portion of the undulating link are shorter than other peaks in the same cylindrical ring to prevent overlap yet still achieve a very low profile, tightly crimped stent onto a catheter.
    Type: Grant
    Filed: August 31, 2005
    Date of Patent: May 19, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Andreina P. Gomez, Diem Uyen Ta
  • Apparatus and method for coating and drying multiple stents
    Patent number: 7534464
    Abstract: A coating and drying apparatus for the application of a coating substance to a stent and drying the stent is provided.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: May 19, 2009
    Assignee: Advanced Cardiovascular Systems Inc.
    Inventors: Arkady Kokish, Yung-Ming Chen, Jason Van Sciver, Roberto Listek
  • Guidewire with optical fiber
    Patent number: 7532920
    Abstract: Apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment of this invention, the apparatus includes a therapeutic guidewire and at least one optical fiber disposed through the therapeutic guidewire, the optical fiber capable of providing diagnostic information before, during, and after the therapeutic treatment. In an embodiment, diagnostic information includes vessel and blood characteristics such as hemodynamic characteristics, hematological parameters related to blood and blood components, and thermal parameters of the vasculature.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: May 12, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Robert D. Ainsworth, Deborah Kilpatrick, Jeong S. Lee, Bridget A. Hurley, Jeffrey T. Ellis, Marc Jalisi, Florencia Lim, Chi Long
  • Nozzle and method for use in coating a stent
    Patent number: 7531202
    Abstract: A nozzle for use in a coating apparatus for the application of a coating substance to a stent is provided.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: May 12, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Mohammed E. Moein
  • Low profile stent with flexible link
    Patent number: 7520892
    Abstract: The invention provides an improved stent design for repairing vasculature, the stent having rings including struts defining first peaks and second peaks, selected second peaks of adjacent rings being connected by links. The stent design incorporates non-linear links with undulating portions extending generally perpendicular to or circumferentially with respect to a longitudinal axis of the stent and adjacent first peaks with different longitudinal lengths such that stent flexibility is increased without sacrificing stent compression for delivery.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: April 21, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Ainsworth, Andreina P. Gomez
  • Blends of poly(ester amide) polymers
    Patent number: 7520891
    Abstract: Provided herein is a poly(ester amide) (PEA) polymer blend and a polymeric coating containing the PEA polymer blend. The PEA polymer blend has a Tg above the Tg of poly(ester amide benzyl ester) (PEA-Bz) or the Tg of poly(ester amide TEMPO). The PEA polymer blend can form a coating on an implantable device, one example of which is a stent. The coating can optionally include a biobeneficial material and/or optionally with a bioactive agent. The implantable device can be used to treat or prevent a disorder such as one of atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: April 21, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jessica R. DesNoyer, Stephen Dirk Pacetti, Lothar W. Kleiner
  • Expandable stents and method for making same
    Patent number: 7513907
    Abstract: The invention is directed to an expandable stent for implantation in a body lumen, such as an artery, and a method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common axis and interconnected by one or more interconnective elements. The individual radially expandable cylindrical elements consist of ribbon-like material disposed in an undulating pattern. Portions of the expanded stent project outwardly into engagement with the vessel wall to more securely attach the stent.
    Type: Grant
    Filed: April 22, 2005
    Date of Patent: April 7, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Lilip Lau, William M. Hartigan, John J. Frantzen
  • Method and apparatus for spray processing of porous medical devices
    Patent number: 7514122
    Abstract: Thermal spray processing and cold spray processing are utilized to manufacture porous starting materials (such as tube stock, wire and substrate sheets) from biocompatible metals, metal alloys, ceramics and polymers that may be further processed into porous medical devices, such as stents. The spray processes are also used to form porous coatings on consolidated biocompatible medical devices. The porous substrates and coatings may be used as a reservoir to hold a drug or therapeutic agent for elution in the body. The spray-formed porous substrates and coatings may be functionally graded to allow direct control of drug elution without an additional polymer topcoat. The spray processes are also used to apply the drug or agent to the porous substrate or coating when drug or agent is robust enough to withstand the temperatures and velocities of the spray process with minimal degradation.
    Type: Grant
    Filed: October 17, 2006
    Date of Patent: April 7, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Pamela A. Kramer
  • Poly(ester amide) block copolymers
    Patent number: 7511103
    Abstract: Provided herein is a copolymer that includes a soft block (A) and a hard block (B) comprising a tyrosine di-peptide. The copolymer can be any of AB, ABA or BAB type block copolymers. The soft block can include a PEA polymer.
    Type: Grant
    Filed: August 5, 2008
    Date of Patent: March 31, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Syed Faiyaz Ahmed Hossainy
  • Guide wire and method of making same
    Patent number: 7507211
    Abstract: An improved intracorporeal device such as a guide wire or other guiding member for use within a patient's body that is at least in part visible under magnetic resonance imaging (MRI) but is not detrimentally affected by the imaging is disclosed. The intracorporeal device has a non-conductive proximal core section, an essentially non-magnetic metallic distal core section that is preferably more flexible than the proximal core section, and that has an MRI visible member or coil in the distal section.
    Type: Grant
    Filed: November 17, 2004
    Date of Patent: March 24, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Douglas H. Gesswein, Emmanuel C. Biagtan
  • Blends of poly(ester amide) polymers
    Patent number: 7507251
    Abstract: Provided herein is a bioabsorbable implantable device comprising a bioactive agent and a poly(ester amide) (PEA) polymer blend.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: March 24, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jessica R. DesNoyer, Stephen Dirk Pacetti, Lothar W. Kleiner
  • System and method for coating implantable devices
    Patent number: 7504125
    Abstract: A method and system of coating an implantable device, such as a stent, are provided.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: March 17, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Wouter E. Roorda, Ni Ding
  • Stent Mandrel Fixture And Method For Reducing Coating Defects
    Publication number: 20090053393
    Abstract: A stent mandrel fixture for supporting a stent during the application of a coating substance is provided.
    Type: Application
    Filed: October 6, 2008
    Publication date: February 26, 2009
    Applicant: Advanced Cardiovascular Systems Inc.
    Inventors: Fuh-Wei Tang, Syed F. A. Hossainy, Dorie M. Happ, Ty Hu
  • Polymer coated guidewire
    Patent number: 7494474
    Abstract: A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under fluoroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: February 24, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Mark T. Richardson, David M. Anderson, Emmanuel C. Biagtan, Lawrence E. Brennan, David H. Burkett, Wayne E. Cornish, Robert C. Esselstein, James Jacobs, Marc M. Jalisi, Daryush P. Mirzaee, Olin J. Palmer, John Schreiner, Kent C. Stalker
  • Polymers containing siloxane monomers
    Patent number: 7494665
    Abstract: A polymer of siloxanes as flexibility monomers and strength monomers is provided. It is also provided a polymer blend that contains a polymer formed of siloxane monomers and strength monomers and another biocompatible polymer. The biocompatible polymer or polymer blend described herein and optionally a bioactive agent can form a coating on an implantable device such as a drug-delivery stent. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: February 24, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Ni Ding, Stephen D. Pacetti
  • Purified polymers for coatings of implantable medical devices
    Patent number: 7491233
    Abstract: A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a purified polymer such as a polyacrylate.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: February 17, 2009
    Assignee: Advanced Cardiovascular Systems Inc.
    Inventors: Ni Ding, Wouter E Roorda
  • Radiopaque catheter tip for enhanced delivery precision of a stent using a guidewire
    Patent number: 7491224
    Abstract: The invention is directed to a self-expanding stent for implantation into a body lumen, such as an artery. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by a plurality of interconnecting members placed on the stent in a collinear arrangement such as to create at least one continuous spine which extends along the length of the stent. The invention is also directed to a stent delivery system for implantation of a stent in a vessel which includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: February 17, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Daniel L. Cox, Matthew J. Fitz, William James Harrison, Michael D. Schultz, Joseph A. Ventura
  • Rapid exchange delivery system for self-expanding stent
    Patent number: 7488342
    Abstract: A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member has a wall defining an opening such as a longitudinal slot; an expanding member such as a leaf spring is connected to the inner member, the leaf spring being adapted to engage with the longitudinal slot so as to maintain rotational alignment between inner member and outer member.
    Type: Grant
    Filed: October 1, 2003
    Date of Patent: February 10, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Winnette S. McIntosh, Christopher J. Tarapata
  • Method of using a stent mounting device to coat a stent
    Patent number: 7485333
    Abstract: A method of coating a stent using a mounting device is provided.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: February 3, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Plaridel K. Villareal
  • Stent mounting device and a method of using the same to coat a stent
    Patent number: 7485335
    Abstract: A stent mounting device and a method of coating a stent using the device are provided.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: February 3, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Plaridel K. Villareal