Patents Assigned to Arkray
  • Chip for plasma generation, plasma generator, and plasma spectrometry method
    Patent number: 9623511
    Abstract: A chip for plasma generation, a plasma generator, and a plasma spectrometry method, having high reproducibility of plasma light emission are described, wherein the chip for plasma generation contains a channel, wherein the channel has a first region, a narrow portion, and a second region, wherein the narrow portion is in communication with the first region and the second region and has a cross-sectional area smaller than the first region and the second region, and the chip further includes an air bubble movement prevention unit that prevents air bubbles generated in the narrow portion from moving from the narrow portion toward the upstream side of the narrow portion.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: April 18, 2017
    Assignee: ARKRAY, Inc.
    Inventors: Takashige Tanaka, Yasunori Shiraki
  • Sample analysis method and solution to be used therein
    Patent number: 9618478
    Abstract: Provided are a sample analysis method using capillary electrophoresis capable of enhancing analysis accuracy, a solution for capillary electrophoresis, and a sample analysis kit. The sample analysis method includes separating and/or detecting a substance to be analyzed in a sample through capillary electrophoresis, in which the substance to be analyzed is separated and/or detected in the presence of a pH buffer substance and a non-surfactant-type zwitterionic substance. Further, the solution for capillary electrophoresis contains a pH buffer substance, a non-surfactant-type zwitterionic substance, and water.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: April 11, 2017
    Assignee: ARKRAY, Inc.
    Inventor: Naotsugu Onuma
  • Enzyme electrode
    Patent number: 9617576
    Abstract: The present invention provides an enzyme electrode composed of a carbon particle on which glucose dehydrogenase (GDH) with flavine adenine dinucleotide (FAD) as a coenzyme is supported and an electrode layer contacting the carbon particle, wherein the carbon particle and/or the electrode layer are/is composed of the carbon particles with a particle diameter of not more than 100 nm and a specific surface area of at least 200 m2/g.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: April 11, 2017
    Assignees: BIOENGINEERING LABORATORIES, LLC, ARKRAY, INC., ULTIZYME INTERNATIONAL LTD.
    Inventors: Wakako Tsugawa, Koji Sode
  • Method for evaluating urine sample, analyzer, and analysis system
    Patent number: 9618519
    Abstract: A method for obtaining information about proteinuria and/or nephropathy from urine samples is provided for evaluating a urine sample that includes detecting proteins in the urine sample with two types of detection reagents that differ in reactivity to at least one urinary protein; and based on an indicator calculated using the results of the detection with the two types of detection reagents.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: April 11, 2017
    Assignee: ARKRAY, Inc.
    Inventors: Ryuichiro Nagamatsu, Shinya Nakajima, Hideko Kosaka
  • Method for measuring color change of oxidation-reduction indicator
    Patent number: 9598715
    Abstract: Provided is a method for measuring a color change of an oxidation-reduction indicator, which method is applicable to measurement of the cariogenic bacterial count and the like. A color change of an oxidation-reduction indicator is measured by a method for measuring a color change of an oxidation-reduction indicator, the method comprising reacting a test reagent with a test sample and measuring a color change, wherein the test reagent contains an oxidation-reduction indicator, an oxidation-reduction promoter, and a halogen salt.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: March 21, 2017
    Assignee: ARKRAY, Inc.
    Inventors: Eiji Nishinaga, Naho Suzuki, Takashi Hama, Isao Fukuta
  • Sensor element, method for manufacturing sensor element, and sensor cartridge
    Patent number: 9597681
    Abstract: A sensor element comprising a tape-shaped mount film; and a plurality of film-shaped sensors bonded on one surface of the mount film, wherein the front and rear film-shaped sensors are spaced at a predetermined distance in a lengthwise direction of the mount film, and a crosswise length of each film-shaped sensor is shorter by a predetermined quantity than a crosswise length of the mount film.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: March 21, 2017
    Assignee: ARKRAY, Inc.
    Inventors: Yuji Kurata, Hisashi Kaneda
  • Method for Isolating or Detecting Rare Cell
    Publication number: 20170072396
    Abstract: A method for treating a blood specimen with which capturing rates for both a small rare cell and a rare cell having a high deformability can be improved in the case where rare cells are contained in a blood specimen. The method for isolating or detecting a rare cell includes treating a blood specimen using a filter to isolate or detect a rare cell in the blood specimen.
    Type: Application
    Filed: March 23, 2016
    Publication date: March 16, 2017
    Applicant: ARKRAY, Inc.
    Inventor: Hidenori Takagi
  • Analysis apparatus, analysis method and analysis system
    Patent number: 9588210
    Abstract: Provided is an analysis apparatus capable of acquiring a measurement result with high reliability that includes: a signal detection unit; a measuring unit; a first temperature detection unit; a second temperature detection unit; and a calculation unit.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: March 7, 2017
    Assignee: ARKRAY, Inc.
    Inventors: Masashi Tsukada, Yasuhide Kusaka
  • Peroxisome proliferator-activated receptor (PPAR) activator, and drugs, supplements, functional foods and food additives using the same
    Patent number: 9573919
    Abstract: The present invention provides a peroxisome proliferator-activated receptor (PPAR) activator, which is free from the problem of side effects, can be taken over a long term and has no characteristics taste. Nobiletin is employed as a PPAR activator. Nobiletin has an excellent PPAR activity and has an excellent adiponectin secretion-promoting effect, and is contained in a large amount in citrus fruits, in particular, in Shiikuwasha (Citrus depressa HAYATA) indigenous to Okinawa (Japan). Since citrus fruits have been consumed for many years, the safety of nobiletin has been proven and besides, nobiletin has a low calorie content. Therefore, it can be taken over a long term. Moreover, because of being tasteless and odorless, nobiletin would not damage the unique taste of a food when added thereto. Therefore, it can be added to foods and taken.
    Type: Grant
    Filed: May 7, 2007
    Date of Patent: February 21, 2017
    Assignee: ARKRAY, Inc.
    Inventor: Takao Sasaki
  • MEASURING METHOD OF SENSOR USING INTERDIGITATED ARRAY ELECTRODE, MEASURING APPARATUS AND COMPUTER READABLE MEDIUM STORING MEASURING PROGRAM
    Publication number: 20170045469
    Abstract: A measuring method of measuring a concentration of a target ingredient in a sample by using a sensor including an interdigitated array electrode that includes a first electrode and a second electrode, and a reagent layer on the interdigitated array electrode, the measuring method includes: applying a voltage to between the first electrode and the second electrode; measuring a first current value of an electric current flowing between the first electrode and the second electrode; measuring a second current value of the current flowing between the first electrode and the second electrode; calculating the concentration of the target ingredient in the sample, based on a third current value; calculating a correction value, based on the first current value and the second current value; and a step of correcting the concentration of the target ingredient in the sample, based on the correction value.
    Type: Application
    Filed: August 9, 2016
    Publication date: February 16, 2017
    Applicants: ARKRAY, Inc., Ultizyme International Ltd., TANAKA KIKINZOKU KOGYO K.K.
    Inventors: Hisashi KANEDA, Yasuhide KUSAKA, Koji SODE
  • Sensor used for measuring biological information on user
    Patent number: 9562909
    Abstract: A sensor includes a substrate that includes an upper substrate and a lower substrate, and an electrode that is provided on the lower substrate, and the upper substrate, the lower substrate, and the electrode are formed by an optically transparent member.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: February 7, 2017
    Assignee: ARKRAY, Inc.
    Inventors: Kazuo Fukuda, Hisashi Kaneda
  • Sensor element, method for manufacturing sensor element, and sensor cartridge
    Patent number: 9561503
    Abstract: A sensor element comprising a tape-shaped mount film; and a plurality of film-shaped sensors bonded on one surface of the mount film, wherein the front and rear film-shaped sensors are spaced at a predetermined distance in a lengthwise direction of the mount film, and a crosswise length of each film-shaped sensor is shorter by a predetermined quantity than a crosswise length of the mount film.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: February 7, 2017
    Assignee: ARKRAY, Inc.
    Inventors: Yuji Kurata, Hisashi Kaneda
  • Measuring apparatus, detection method, electrochemical sensor and measuring system
    Patent number: 9562875
    Abstract: A measuring apparatus for measuring a substrate concentration by using a sensor including an enzyme reagent layer includes a state detecting unit that applies a first voltage and a second voltage different from the first voltage to the sensor to detect a state of the enzyme reagent layer based on a difference between a first response current value obtained under application of the first voltage and a second response current value obtained under application of the second voltage.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: February 7, 2017
    Assignee: ARKRAY, Inc.
    Inventor: Yosuke Murase
  • Liquid reagent of thyroid hormone-immobilized carrier and use thereof
    Patent number: 9551723
    Abstract: A liquid reagent of a stabilized thyroid hormone-immobilized carrier, by which a thyroid hormone can be measured easily in a short time and at low cost, is provided. The liquid reagent of a thyroid hormone-immobilized carrier according to the present invention includes: a thyroid hormone-immobilized carrier; and a solvent, and a pH of the solvent containing the thyroid hormone-immobilized carrier is in a range from 8.7 to 11.5. The detection of a thyroid hormone using the liquid reagent of the present invention can be carried out by competitively binding a thyroid hormone in a sample and the thyroid hormone-immobilized carrier in the liquid reagent with an anti-thyroid hormone antibody and detecting a composite of the thyroid hormone-immobilized carrier and the anti-thyroid hormone antibody.
    Type: Grant
    Filed: February 2, 2012
    Date of Patent: January 24, 2017
    Assignee: ARKRAY, Inc.
    Inventor: Naotsugu Onuma
  • Reducing power analysis method and reducing power analysis reagent
    Patent number: 9546951
    Abstract: A reducing power analysis method for minimizing peak wavelength shift in a sample, comprising a reduction step of reducing a dye reagent containing a ferric compound and a cyanide at pH conditions of 2.4 or lower in the presence of a sample; and an optical measurement step of optically measuring a peak wavelength of a reduced form of the dye reagent obtained in the reduction step.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: January 17, 2017
    Assignee: ARKRAY, Inc.
    Inventor: Kazuhiro Ohmiya
  • Nuclear Medicine Diagnostic Imaging Agent
    Publication number: 20170000912
    Abstract: Provided is a radioactive labeled compound capable of detecting a secondary mutation of an epidermal growth factor receptor, where the compound is represented by Formula (1) or a pharmaceutically acceptable salt thereof, where Y, L1, R1 and R2 are as defined.
    Type: Application
    Filed: April 28, 2016
    Publication date: January 5, 2017
    Applicants: Kyoto University, ARKRAY, Inc.
    Inventors: Hideo Saji, Hiroyuki Kimura, Hirokazu Matsuda, Shuichi Nakanishi
  • Nuclear Medicine Diagnostic Imaging Agent
    Publication number: 20170000913
    Abstract: Provided is a radioactive labeled compound capable of detecting a secondary mutation of an epidermal growth factor receptor, where the compound is represented by Formula (1) or a pharmaceutically acceptable salt thereof, where R1, R2, and Y are as defined.
    Type: Application
    Filed: July 1, 2016
    Publication date: January 5, 2017
    Applicants: Kyoto University, ARKRAY, Inc.
    Inventors: Hideo Saji, Hiroyuki Kimura, Anna Miyazaki, Hirokazu Matsuda, Shuichi Nakanishi
  • Buffer composition
    Patent number: 9528963
    Abstract: Provided is a buffer composition capable of suppressing temperature dependency of the pH of a buffer solution, and a specimen analysis method and a specimen analysis system using the buffer composition, wherein the buffer composition contains a buffer substance A showing a positive correlation between temperature and pH and a buffer substance B showing a negative correlation between temperature and pH.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: December 27, 2016
    Assignee: ARKRAY, Inc.
    Inventors: Naotsugu Onuma, Miho Fukuda
  • Protein concentration assay method including pH measurement
    Patent number: 9523643
    Abstract: Provided is a protein concentration assay method that uses a protein indicating reagent and that enables highly accurate assay. The protein concentration assay method includes: optically analyzing a color exhibited after a sample to be assayed and a protein indicating reagent are brought into contact with each other; measuring pH of the sample to be assayed; and assaying a concentration of protein in the sample based on the result of the optical analysis, the measured value of pH, and data for protein concentration assay, wherein the protein indicating reagent is a protein indicating reagent whose color varies with pH and a concentration of protein, and the data for protein concentration assay include information indicating a way to assay the result of the optical analysis corresponding to the measured value of pH.
    Type: Grant
    Filed: October 15, 2012
    Date of Patent: December 20, 2016
    Assignee: ARKRAY, INC.
    Inventors: Satoshi Majima, Shinya Nakajima
  • Biosensor and biosensor manufacturing method
    Patent number: 9506889
    Abstract: A biosensor manufacturing method including a sheet material forming process and a dicing process. In the sheet material forming process a sheet material with plural biosensor forming sections is formed. Each of the biosensor forming sections includes a first base plate, a second base plate stacked on the first base plate and forming a capillary between the second base plate and the leading end portion of the first base plate for sucking in sample liquid, and a hydrophilic layer formed on the second base plate at least in a region facing the capillary. In the dicing process plural biosensors are obtained by dicing the sheet material with a blade from the first base plate side at the leading end of each of the biosensor forming sections, such that the leading end of the capillary opens onto the leading end face of the first base plate and the second base plate.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: November 29, 2016
    Assignee: ARKRAY, INC.
    Inventors: Yoshimitsu Matsuura, Shuzo Kanda