Abstract: When light beams of two different wavelengths applied from an excitation light source are made incident on a nonlinear optical crystal having a unique nonlinear coefficient, the nonlinear optical crystal generates THz waves resulting from difference frequency generation according to the nonlinear coefficient that the crystal itself has and SHG waves in which the light beams of two different wavelengths have been wavelength converted in accordance with the nonlinear coefficient. The generated THz waves pass through or are reflected from a sample and are detected by a THz detector. The SHG waves are detected by a SHG detector. A control unit acquires THz measurement values T from the THz detector, acquires SHG measurement values S from the SHG detector, and uses baseline THz measurement values TB and baseline SHG measurement values SB acquired without the sample to perform baseline correction using (T/S)/(TB/SB).

Abstract: A probe for detecting a polymorphism in ab1 gene, comprising at least one fluorescence-labeled oligonucleotide.

Abstract: A precursor of a molecular probe for imaging of pancreatic islets is provided.

Abstract: A sample analyzer which transports and analyzes samples, includes: a first measurement apparatus which measures samples; a second measurement apparatus which is arranged downstream, in a transport direction, from the first measurement apparatus, and which measures samples; a transporting apparatus which transports samples to a first supply position for supplying a sample to the first measurement apparatus, and to a second supply position for supplying a sample to the second measurement apparatus; and a controller which controls transportation of a sample present at the first supply position, in accordance with a processing status of a sample present at the second supply position.

Abstract: A transport apparatus for transporting a sample as an analysis objective in a state of being accommodated in a sample container comprises a judging unit which judges whether or not the sample container is positioned at each of first and second collection positions for collecting the sample from the sample container in order to perform each of first and second analysis processes and which outputs each of judgment results thereof as first and second collection position data; and a sample container identification unit which performs individual identification of the sample container in a transport route for the sample container and which outputs an identification result thereof as individual identification data.

Abstract: The present invention provides a sensor insertion and removing device which is user-friendly and which does not cause infection. The sensor insertion and removing device has a sensor; a puncture blade member; a housing which houses the sensor and the puncture blade member; a guide part which is provided within the housing and which glidably supports the puncture blade member; a puncture blade operating part which inserts the sensor under the skin by causing the puncture blade member to glide along the guide part integrally with the sensor, upon delivering the puncture blade member outside the housing to puncture the skin, and which causes the puncture blade member to glide along the guide part in a state of being separated from the sensor, upon removing the puncture blade member from under the skin into the housing, and a sensor operating part which pulls out the sensor from under the skin and removes it from under the skin into the housing.

Abstract: This aims to provide an analyzing tool including a substrate, a first electrode formed on the substrate and having an action pole, a second electrode formed on the substrate and having an opposed pole, and a first regulating element for regulating such a contact area in the action pole as to contact a specimen. The analyzing tool further comprises second regulating elements for regulating the effective area for electron transfers in at least one of the action pole and the opposed pole.

Abstract: A specimen measurement system simplifies the function of a measurement device and facilitates measurement under an appropriate condition. Use is made of a specimen measurement device suitable for the system. The specimen measurement device includes a measurement unit, a measurement condition decision unit, and a communication unit. The measurement unit measures a specific component contained in the specimen. The measurement condition decision unit decides suitability of measurement conditions necessary for the measurement, and generates measurement condition data including decision result about the suitability of the measurement conditions. The communication unit transmits the measurement condition data through wireless communication.

Abstract: The disclosure relates to probes for detecting a polymorphism in the IL28B gene and in the ITPA gene, and methods of use thereof.

Abstract: Provided in the present disclosure is a probe for detecting polymorphism that enables a simple detection of polymorphism in the CYP3A gene with high sensitivity.

Abstract: Disclosed is a method of amplifying a polynucleotide, comprising: (a) mixing primers for amplifying the polynucleotide, a polymerase, nucleotide substrates and a template polynucleotide, and (b) amplifying the polynucleotide by polymerase reaction, wherein the polymerase has an amino acid sequence consisting of SEQ ID NO:1 or an amino acid sequence with at least 85% sequence identity to SEQ ID NO:1, and an amino acid residue corresponding to, or at position 651 of the amino acid sequence has been replaced with glutamic acid.

Abstract: An analysis device is disclosed which includes an electron detection medium to obtain information needed for analyzing an analyte in correlation with an electron transfer level, and a reagent part which is disposed on the electron detection medium and includes an electron transporting substance to transport electrons between the analyte and the electron detection medium, the electron transporting substance including a water-soluble aromatic heterocycle compound, and being free of a metal complex. An analysis method using the analysis device is also disclosed.

Abstract: The present invention provides a device that decreases deformation during manufacturing of the device, provides a firm joint without use of an adhesive, and allows chemical modification of a channel during manufacturing of the device. The device includes two joined substrates, and a concavity is formed on at least one of the opposing surfaces of the two substrates so as to make a channel, where the two substrates are joined together by a covalent bond via a crosslinking agent (A), and the crosslinking agent (A) is exposed on an inner wall surface of the channel.

Abstract: A sensor cartridge for supplying a sensor is used. The sensor cartridge includes a casing within which the plurality of sensors can be arranged, and that allows a sample to be introduced to a sensor located at a preset location, and a connection structure. The connection structure electrically connects an external device and a sensor electrode of the sensor located at the preset location. The casing is formed so as to be held by the external device when the external device and the sensor electrode of the sensor are electrically connected via the connection structure.

Abstract: An apparatus and a method that can detect a defective analytical device due to the scattering of a reagent are provided. In particular, a blood glucose level meter (measuring apparatus) 1 is configured to measure a target component of a biological sample using a reagent. The apparatus includes a second measuring unit (measuring unit) 31b configured to measure an electrical response to a detection signal applied to a pair of hematocrit electrodes (test electrode pair), and a control unit 33 configured to determine the presence or absence of the reagent on the pair of hematocrit electrodes based on the measured electrical response.

Abstract: The present invention provides a code reading device capable of associating various kinds of information with obtained data with ease simply by connecting the code reading device to a data holding device. A code reading device (1) includes a code reader (15) for reading code information, a memory (31), and a data processing control portion (32). The data processing control portion (32) stores code information read by the code reader in a code information storage area (311) of the memory (31), reads data from a data holding device when the data holding device is connected to the code reading device and stores the data in a data storage area (312) of the memory (31), and sends to a personal computer the data in the data storage area (312) in a state of being associated with the code information in the code information storage area (311) when the personal computer is connected to the code reading device.

Abstract: Detection probes are provided that are capable of detecting a sequence to be detected containing a mutation even when a sequence not to be detected containing no mutation coexists with the sequence to be detected containing a mutation, which are different only in a single base from each other. At least one oligonucleotide selected from the group consisting of SEQ ID NOs: 2˜16 is used as a probe. Even in a sample containing an abl gene in which a mutation has occurred and an abl gene in which no mutation has occurred, the use of such probes in, for example, Tm analysis allows the mutation to be detected.

Abstract: Provided is a dry reagent that allows measuring with good precision, in accordance with a transmission method that utilizes light of the ultraviolet region, increases or decreases of a nicotinamide coenzyme, in order to quantify a component contained in a liquid sample. A dry reagent 4 for performing a quantitative analysis of a specific component in a liquid sample S contains a nicotinamide coenzyme and a leveling agent for smoothing the dry reagent 4. Increases or decreases of the nicotinamide coenzyme are measured in accordance with a transmission method that utilizes light of the ultraviolet region. The leveling agent is a combination of an alkali and at least one type selected from among a saccharide and a surfactant.

Abstract: The present invention provides a method of pretreating a sample containing a glycated amine as an analyte, thereby enabling highly reliable measurement of a glycated amine. A glycated amino acid in the sample is degraded by causing a fructosyl amino acid oxidase (FAOD) to act thereon, and thereafter, a FAOD further is caused to act on the glycated amine as the analyte in the sample to cause a redox reaction. The amount of the glycated amine is determined by measuring the redox reaction. The substrate specificity of the FAOD caused to act on the glycated amino acid may be either the same as or different from that of the FAOD caused to act on the glycated amine. When using the same FAOD, a FAOD is caused to act on the glycated amino acid to degrade it, and thereafter, the sample is treated with a protease to inactivate the FAOD and also to degrade the glycated amine.