Patents Assigned to Corixa
  • Co-encapsulated WT1 polypeptide and immunostimulant microsphere formulations and methods thereof
    Publication number: 20050260217
    Abstract: Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 WT1 polypeptides in combination with one or more immunostimulants, either independently or co-encapsulated with biodegradable polymeric microspheres. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases.
    Type: Application
    Filed: March 3, 2005
    Publication date: November 24, 2005
    Applicant: Corixa Corporation
    Inventors: Mark Johnson, Afsaneh Mozaffarian, Sally Mossman, Charlie Meert
  • Compositions and methods for the therapy and diagnosis of lung cancer
    Publication number: 20050261166
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
    Type: Application
    Filed: July 17, 2003
    Publication date: November 24, 2005
    Applicant: Corixa Corporation
    Inventors: Tongtong Wang, David Peckham, Marc Retter, Gary Fanger
  • Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
    Publication number: 20050260177
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as colon cancer, are disclosed. Compositions may comprise one or more colon tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a colon tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as colon cancer. Diagnostic methods based on detecting a colon tumor protein, or mRNA encoding such a protein, in a sample are also provided.
    Type: Application
    Filed: April 15, 2005
    Publication date: November 24, 2005
    Applicant: Corixa Corporation
    Inventors: Jiangchun Xu, Michael Lodes, Heather Secrist, Darin Benson, Madeleine Meagher, John Stolk, Tongtong Wang, Yuqiu Jiang, Carole Smith, Gordon King, Aijun Wang, Jonathan Clapper, Yasir Skeiky, Gary Fanger, Thomas Vedvick, Darrick Carter
  • Compositions and methods for the therapy and diagnosis of ovarian cancer
    Patent number: 6962980
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.
    Type: Grant
    Filed: April 4, 2001
    Date of Patent: November 8, 2005
    Assignee: Corixa Corporation
    Inventors: Jennifer L. Mitcham, Gordon E. King, Paul A. Algate
  • Compounds and methods for immunotherapy and diagnosis of tuberculosis
    Patent number: 6962710
    Abstract: Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
    Type: Grant
    Filed: February 25, 2002
    Date of Patent: November 8, 2005
    Assignee: Corixa Corporation
    Inventors: Steven G. Reed, Yasir A. W. Skeiky, Davin C. Dillon, Antonio Campos-Neto, Raymond Houghton, Thomas S. Vedvick, Daniel R. Twardzik, Michael J. Lodes, Ronald C. Hendrickson
  • Compositions and methods for the therapy and diagnosis of lung cancer
    Patent number: 6960570
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: November 1, 2005
    Assignee: Corixa Corporation
    Inventors: Tongtong Wang, Robert A. Henderson, Teresa M. Foy
  • Compositions and methods for the therapy and diagnosis of breast cancer
    Patent number: 6958361
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: October 25, 2005
    Assignee: Corixa Corporation
    Inventors: Raymond L. Houghton, Paul R. Sleath, David H. Persing
  • Compounds and methods for treatment and diagnosis of chlamydial infection
    Publication number: 20050232941
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: April 19, 2005
    Publication date: October 20, 2005
    Applicant: Corixa Corporation
    Inventors: Ajay Bhatia, Jeff Guderian, Yasir Skeiky, Jean-Francois Maisonneuve
  • Certain aminoalkyl glucosaminide phosphate compounds and their use
    Publication number: 20050227943
    Abstract: Compounds that are adjuvants and immunoeffectors are described and claimed. The compounds augment antibody production in immunized animals as well as stimulate cytokine production and activate macrophages. Compositions and methods for using the compounds as adjuvants and immunoeffectors are also disclosed.
    Type: Application
    Filed: July 8, 2004
    Publication date: October 13, 2005
    Applicant: Corixa Corporation
    Inventors: David Johnson, David Persing
  • Compounds and methods for diagnosis of tuberculosis
    Patent number: 6949246
    Abstract: Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: September 27, 2005
    Assignee: Corixa Corporation
    Inventors: Steven G. Reed, Yasir A. W. Skeiky, Davin C. Dillon, Antonio Campos-Neto, Raymond Houghton, Thomas S. Vedvick, Daniel R. Twardzik, Michael J. Lodes, Ronald C. Hendrickson
  • Compositions and methods for the therapy and diagnosis of prostate cancer
    Patent number: 6943236
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: September 13, 2005
    Assignee: Corixa Corporation
    Inventors: Jiangchun Xu, Davin C. Dillon, Jennifer L. Mitcham, Susan L. Harlocker, Yuqiu Jiang, Michael D. Kalos, Gary R. Fanger, Marc W. Retter, John A. Stolk, Craig H. Day, Thomas S. Vedvick, Darrick Carter, Samuel X. Li, Aijun Wang, Yasir A. W. Skeiky, William T. Hepler, Robert A. Henderson, John Hural, Patricia D. McNeill, Raymond L. Houghton, Carlota Vinals y de Bassols, Teresa M. Foy, Yoshihiro Watanabe, Madeleine Joy Meagher
  • Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
    Publication number: 20050192250
    Abstract: Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for selectively stimulating immune responses in animals and plants.
    Type: Application
    Filed: April 14, 2005
    Publication date: September 1, 2005
    Applicant: Corixa Corporation
    Inventors: Jory Baldridge, David Johnson, Christopher Cluff
  • Compositions and methods for therapy and diagnosis of lung cancer
    Patent number: 6933363
    Abstract: Compositions for the therapy and diagnosis of cancer, such as lung cancer, are disclosed. Compositions may comprise cancer-associated L552S polypeptides, for example, as set forth illustratively in SEQ ID NO:786, or portions or variants thereof. Such compositions may be used, for example, in the diagnosis, prevention, and treatment of diseases such as lung cancer.
    Type: Grant
    Filed: March 6, 2000
    Date of Patent: August 23, 2005
    Assignee: Corixa Corporation
    Inventors: Tongtong Wang, Chaitanya S. Bangur
  • Compounds and methods for diagnosis of tuberculosis
    Publication number: 20050181419
    Abstract: Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.
    Type: Application
    Filed: March 15, 2005
    Publication date: August 18, 2005
    Applicant: Corixa Corporation
    Inventors: Steven Reed, Yasir Skeiky, Davin Dillon, Antonio Campos-Neto, Raymond Houghton, Thomas Vedvick, Daniel Twardzik, Michael Lodes, Ronald Hendrickson
  • Compounds and methods for treatment and diagnosis of chlamydial infection
    Patent number: 6919187
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: July 19, 2005
    Assignee: Corixa Corporation
    Inventors: Ajay Bhatia, Jeff Guderian, Yasir A. W. Skeiky, Jean-Francois L. Maisonneuve
  • Compositions and methods for the therapy and diagnosis of colon cancer
    Publication number: 20050147615
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly colon cancer, are disclosed. Illustrative compositions comprise one or more colon tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly colon cancer.
    Type: Application
    Filed: October 7, 2004
    Publication date: July 7, 2005
    Applicant: Corixa Corporation
    Inventors: Gordon King, Madeleine Meagher, Jiangchun Xu, Heather Secrist
  • Compositions and methods for the therapy and diagnosis of lung cancer
    Patent number: 6914132
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as lung cancer, are disclosed. Compositions comprise one or more polynucleotides that encode a lung tumor protein, or a fragment or variant thereof. The compositions may be used to detect an mRNA encoding a lung tumor protein in a sample.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: July 5, 2005
    Assignee: Corixa Corporation
    Inventors: Tongtong Wang, Liqun Fan
  • Compositions and methods for the therapy and diagnosis of lung cancer
    Publication number: 20050142620
    Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
    Type: Application
    Filed: August 19, 2004
    Publication date: June 30, 2005
    Applicant: Corixa Corporation
    Inventors: Chaitanya Bangur, Barbara Zehentner-Wilkinson
  • Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
    Patent number: 6911434
    Abstract: Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ cyclic AGPs for selectively stimulating immune responses in animals and plants.
    Type: Grant
    Filed: February 4, 2002
    Date of Patent: June 28, 2005
    Assignee: Corixa Corporation
    Inventors: Jory R. Baldridge, David A. Johnson, Christopher W. Cluff
  • Compounds and methods for immunotherapy and diagnosis of tuberculosis
    Publication number: 20050136069
    Abstract: Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
    Type: Application
    Filed: January 3, 2005
    Publication date: June 23, 2005
    Applicant: CORIXA CORPORATION
    Inventors: Steven Reed, Yasir Skeiky, Davin Dillon, Antonio Campos-Neto, Raymond Houghton, Thomas Vedvick, Daniel Twardzik, Michael Lodes, Ronald Hendrickson