Abstract: The present invention refers to a composition comprising uric acid for its use in the treatment of brain stroke in a patient treated by means of mechanical thrombectomy.

Abstract: The invention relates to a separation matrix comprising at least 11 mg/ml Fc-binding ligands covalently coupled to a porous support, wherein: a) the ligands comprise multimers of alkali-stabilized Protein A domains, and b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50,v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.

Abstract: The present invention consists in a subassembly (1) of a linkage (2) of a wiper mechanism comprising: a bearing (3), a crank (5) articulated on the bearing (3) having a first end (51) connected to the bearing (3) and a second end (53) including a ball joint (7), and a link (9) one end of which is connected by the ball joint (7) to the crank (5), characterized in that at least the crank (5) includes a first through-opening and in that the subassembly (1) comprises a locking element (11) intended to be positioned in the first through-opening and configured to block relative movement between the link (9) and the crank (5).

Abstract: Example embodiments relate to systems and methods for heart rate detection with motion artifact reduction. One embodiment includes an electronic system for heart rate detection. The electronic system includes a random sampling sensor module. The random sampling sensor module includes a first sensor circuit configured to provide nonuniform random samples below a Nyquist rate of a photoplethysmographic signal. The random sample sensor module also includes a second sensor circuit configured to provided nonuniform random samples below a Nyquist rate of a motion signal. The motion signal and the photoplethysmographic signals are sampled with an equivalent pattern. The electronic system also includes a heart rate detection module. The heart rate detection module is configured to calculate a heart rave value based on frequencies corresponding to peak powers of calculated power spectral density value sets corresponding to the photoplethysmographic signals in a frequency range of interest.

Abstract: The present disclosure provides a support for household appliance and a household appliance. The support for household appliance comprises a hydraulic plate; a sheath, which is fixedly connected with the hydraulic plate; a regulating element, which is arranged in the sheath and is axially movable relative to the sheath; an accommodation chamber, which is formed by the hydraulic plate, the sheath and the regulating element; a hydraulic medium, which is arranged in the accommodation chamber and is compressed/expands depending on pressure changes to drive the regulating element to axially move in the sheath for leveling; at least two supports for household appliance communicate with each other to allow the hydraulic medium to flow between the supports; and the hydraulic plate is provided with a one-way flow stop mechanism for conducting the hydraulic medium in one direction.

Abstract: A method of manufacturing a cover element for a motor vehicle comprises placing, in a mold, a stack formed at least of a covering material made of textile, of leather, of skin, or of a synthetic material, and of a foam layer at the rear surface of the covering material, the foam layer integrating reinforcing elements.

Abstract: A gaming apparatus having electronic input controls therein includes: a player input panel; a video display system; and a gaming processor. The player input panel may have a first input control specific to providing a command to the gaming processor and the player input panel. The command enables a second player input control on the player input panel. This second player input control is specific to alteration of game play so that physical activity at the player panel will enter commands to the gaming controller to execute gaming play without placing any economic value at risk during a demonstration period. The gaming processor allows the demonstration period to continue for only a predetermined time limit or event occurrence that does not result in resolution of a wager.

Abstract: A baggage management system for a vehicle that includes a storage bin that defines a bin interior, a baggage monitoring system associated with the storage bin, and a display member associated with the storage bin. The baggage monitoring system is configured to monitor the positioning of baggage within the bin interior and the display member is configured to provide baggage positioning information to passengers.

Abstract: Provided herein are novel solid forms of N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4?-(morpholinomethyl)-[1,1?-biphenyl]-3-carboxamide hydrochloride, and related compositions and methods.

Abstract: The invention provides compounds of formula (I): or a pharmaceutically-acceptable salt thereof, wherein the variables are defined in the specification, that are inhibitors of JAK kinases, particularly JAK3. The invention also provides crystalline forms, pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.

Abstract: A washing machine includes a box body, an inner tub in the box body, a device for driving the inner tub to rotate, and a water collecting device at the bottom of the inner tub. The inner tub is a water containing tub during washing/rinsing. The outer wall of the inner tub is provided with a dewatering channel communicating with the inner tub for draining water discharged from the inner tub. The water collecting device includes a water collecting cavity with an upper opening, the bottom wall of the water collecting cavity is provided with a recessed portion, and a water outlet end of the dewatering channel downwardly extends into the recessed portion. The outlet end of the dewatering channel is inserted into the recessed portion on the bottom wall of the water collecting cavity, so that water collection and drainage are facilitated.

Abstract: The present invention provides a modified nucleic acid monomer compound having a specific backbone such as 2-ethylglycerol or methoxymethyl-1,3-propanediol backbone instead of a ribose or deoxyribose backbone of a nucleoside, and an oligonucleic acid analogue containing the monomer compound as at least one of building blocks. The oligonucleic acid analogue containing the nucleic acid monomer compound of the present invention allows provision of an oligonucleic acid analogue having excellent biological stability and/or target gene silencing activity.

Abstract: A dart game apparatus 100 is provided with: a dart board in which a dart can stick and a plurality of segments are demarcated; a first detecting part 100 that detects a position of a point where the dart stuck in the dart board; a second detecting part 102 that detects a segment of the point where the dart stuck from the plurality of segments; a correcting part 104 that corrects the position detected by the first detecting part 100 based on the segment detected by the second detecting part 102 if a segment corresponding to the position detected by the first detecting part 100 is different from the segment detected by the second detecting part 102; and an outputting part 106 that output the position detecting by the first detecting part 100 or position corrected by the correcting part 104.

Abstract: The invention provides compounds of formula (I): which contain a 4-membered heterocyclic amide, where the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat respiratory diseases, and processes and intermediates useful for preparing such compounds.

Abstract: The present invention relates generally to proteasome inhibiting ?-lactam compounds useful for the treatment of cancer and neurodegenerative disorders. The invention also provides pharmaceutical compositions and extended release formulations of said compounds, and medical uses of said compounds and/or pharmaceutical compositions to treat cancer and neurodegenerative disorders.

Abstract: The present invention relates to an expandable infusion packet (1, 5), wherein the infusion packet is in a permanently compressed state in the absence of water and converts to an expanded state in the presence of water.

Abstract: An injection station of an injection blow molding machine. The injection station comprises a lower die plate and an upper die plate, with lower and upper die plates being shiftable relative to one another between an open position and a closed position. The injection station additionally includes one or more lower mold halves rigidly secured to the lower die plate. The injection station additionally includes one or more upper mold halves floatingly secured to the upper die plate such that positions of the upper mold halves are configured to be adjusted with respect to the upper die plate. Each of the lower mold halves corresponds with an upper mold half to present one or more mold cavities when the lower and upper die plates are in the closed position.

Abstract: A thermal desalination system, comprising a multi-effect evaporator comprising a plurality of effects, configured to produce product water and brine and a fluidized bed crystallizer, configured to remove dissolved minerals and/or solids from the water, wherein the fluidized bed crystallizer is disposed between at least two effects of the multi-effect evaporator.

Abstract: The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.

Abstract: An automatic leveling washing machine includes a shell and a barrel assembly. A bottom plate of the shell has leveling bottom feet with hydraulic medium therein and hydraulic medium flows between leveling bottom feet to execute automatic leveling washing machine. The bottom plate of the shell has mounting grooves for fixing and mounting leveling bottom feet. Hydraulic medium and some gas flows inside each leveling bottom foot or between leveling bottom feet. The amount of compression of the leveling bottom foot which is under bigger pressure is big, and the amount of compression of the leveling bottom foot which is under smaller pressure can still stretch, thereby automatically realizing the leveling of the height. The mounting groove effectively and quickly positions the leveling bottom feet. A circumferential surface of the mounting groove protects the leveling bottom feet and allows high reliability of operation.