Abstract: Compounds of formula (I): wherein Het, R3, R4, R5, R7, R8, R9, T, p, p?, q, and q? are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.

Abstract: Compounds of formula (I): wherein A1, A2, Ra, Rb, Rc, Rd, R3, R4, R5 and T are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.

Abstract: Methods and systems for solving various computational problems with quantum processors are provided. Such quantum processors comprise a plurality of quantum devices together with a plurality of coupling devices. The quantum processor is initialized by setting states of the quantum devices and coupling devices and allowed to evolve to a final state which approximates a natural ground state of the computational problem. The final state can include values of nodes arranged in a lattice in the quantum processor and can represent a solution to the computational processor. The computational problem can have complexity P, NP, NP-Hard, or NP-Complete and may be mapped to a quantum processor with nearest-neighbor and next-nearest-neighbor couplings. The solution to the computational problem can be read out from the quantum processor and transmitted as a data signal embodied in a carrier wave.

Abstract: The present invention relates to a method and facility for breeding insects. According to the invention, the insect breeding facility comprises a spawning area comprising spawning containers which are adapted to receive adult insects and insect food, wherein at least one spawn structure is provided in each spawning container, in which spawn structures the mother insects will spawn their eggs. The plurality of spawning containers are stacked in one or more stacks of containers. Furthermore a hatch area is provided in which the eggs will hatch and which allows periodical harvesting of baby larvae from the hatch area.

Abstract: Yoke (14a?) for drive arm (14?) of a wiper (12) of a windscreen wiper system (10?) of a vehicle, in particular a motor vehicle, said yoke including: a connecting part (30?) of elongate general shape and including an interior longitudinal end (30a?) intended to be connected to a drive means of the arm and an exterior longitudinal end (30b?), a terminal part (28?) of the arm forming a yoke for fixing it to said wiper, said terminal part having an elongate general shape and including an exterior longitudinal end (28b?) and an interior longitudinal end (28a?) that is intended to be situated on the side of said drive means, characterized in that the exterior longitudinal end (30b?) of said connecting part (30?) is connected to said terminal part (28?) in a zone (C) that is longitudinally spaced from said interior longitudinal end (28a?) of the terminal part (28?).

Abstract: Systems and methods disclosed provided a virtual reality experience, including: a set of motorized pads for coupling to feet of a user; a means of communication between the set of motorized pads and a computing environment operating a virtual reality headset; such that the set of motorized pads are configured to provide pressure on a user's feet as an avatar within a virtual environment traverses the environment. Systems and methods disclosed further provide a multiuser virtual reality experience. Systems and methods disclosed further provide a multiuser experience including generation of a common environment viewable in the virtual reality headsets; and recording a tour including audio data as the first user describes the common environment.

Abstract: A safety device with fall arrest and descending modes includes a housing, a drum, a lifeline, first and second brake assemblies, and a control. The drum is rotatably operatively connected to the housing. The lifeline has an intermediate portion interconnecting a first end and a second end. The first end is operatively connected to the drum. The first and second assemblies are operatively connected to the drum. The control is operatively connected to the first and second brake assemblies and has a first position and a second position. The first position selectively engages the first brake assembly in a descending mode and the second position selectively engages the second brake assembly in a fall arrest mode.

Abstract: A wooden drum shell that is treated by direct heating by exposure to a flame to alter the state of fibers in an outer layer of the drum shell relative to the untreated drum shell or inner fibers below the outermost layer. A method of manufacturing a treated drum shell includes selecting a wooden starting material, forming an untreated drum shell from the starting material, and exposing the drum untreated drum shell directly to a flame.

Abstract: The present disclosure relates to circuits, systems, and methods of operation for a memory device. In an example, a memory device includes a plurality of memory cells, each memory cell having a variable impedance that varies in accordance with a respective data value stored therein; and a read circuit configured to read the data value stored within a selected memory cell based upon a variable time delay determination of a signal node voltage change corresponding to the variable impedance of the selected memory cell.

Abstract: The present invention relates to process for the preparation of 5-(4-cyano phenoxy)- 1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole represented by the following structural formula-1 and polymorphs thereof. The present invention also relates to salts of 5-(4-cyano phenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and process for their preparation and their use in the preparation of pure compound of the formula-1.

Abstract: A supporting and leveling device for a household appliance and a household appliance are provided, wherein the supporting and leveling device is provided with leveling bottom legs. Each of the leveling bottom legs includes a hydraulic connection piece, a connection sleeve, a flexible deformation membrane, an adjustment leg, and a hydraulic medium. An edge of the flexible deformation membrane is hermetically mounted at a joint of the hydraulic connection piece and the connection sleeve to form an accommodating chamber together with the hydraulic connection piece. The hydraulic medium is arranged in the accommodating chamber. When the leveling bottom leg is arranged on an uneven supporting surface, the adjustment leg axially moves along the connection sleeve to squeeze the flexible deformation membrane to deform, so as to change a volume of the accommodating chamber, and the hydraulic medium is stressed to act on the adjustment leg for leveling.

Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.

Abstract: Provided are methods and compositions conditioning a patient for an allogeneic transplantation, wherein the patient's hematopoietic stem cells (HSCs) are depleted with an HSC-depleting composition and the patient is then administered allogeneic cells selected from bone marrow cells, umbilical cord blood cells, hematopoietic stem and progenitor cells (HSPCs), peripheral blood CD34+ cells, and peripheral blood CD34+ and CD90+ cells; optionally the patient is also administered a medicament selected from the group consisting of a T-cell depleting or inhibiting antibody or antibody fragment, NK-cell depleting or inhibiting antibody or antibody fragment, immunosuppressive drug, and any combination thereof. The HSC-depleting composition comprises a compound selected from the group consisting of: an antibody or antibody fragment with specific binding affinity to a protein displayed at the HSC surface, a conjugate comprising an HSC-recognition molecule and a toxin, and any combination thereof.

Abstract: A system and method of conducting a drone race or game in a contained area is disclosed herein. The system may also include cameras attached to the drones and the video feed from the camera is transmitted to a computing device used to control the drone and to display the video feed. The system may also use computing devices and monitors to display the video feeds from the cameras attached to the drones. The system may also be configured as a game with information points.

Abstract: Embodiments of the present invention may be used to perform measurement of surfaces, such as external and internal surfaces of the human body, in full-field and in 3-D. Embodiments of the present invention may include an electromagnetic radiation source, which may be configured to project electromagnetic radiation onto a surface. The electromagnetic radiation source may be configured to project the electromagnetic radiation in a pattern corresponding to a spatial signal modulation algorithm. The electromagnetic radiation source may also be configured to project the electromagnetic radiation at a frequency suitable for transmission through the media in which the radiation is projected. An image sensor may be configured to capture image data representing the projected pattern.

Abstract: An aerosol dispenser (1) comprising a pressurised aerosol can (2) and a closure (3) comprising an aerosol valve (4) held within a retention chassis (5), said retention chassis (5) being associated with a flexible sealing collar (6) designed to radially surround the retention chassis (5) and to seal against the edge of an opening (7) in the aerosol can (2), wherein the retention chassis (5) is axially moveable relative to the sealing collar (6) and wherein the sealing collar (6) is of outer 7A diameter greater than the inner diameter of the opening (7) in the aerosol can (2) and is sufficiently flexible to flex through the opening (7) in the aerosol can (2) when the retention chassis (5) is in a first axial position relative to the sealing collar (6) and wherein the sealing collar (6) is firmly held 2 against the edge (7) of the opening (8) in the aerosol can (2) when the retention chassis (5) is in a second axial position relative to the sealing collar (6).

Abstract: The invention pertains to a method for manufacture and use of pesticides or agricultural spray adjuvants that counteracts the effects of hard water cat ions on anionic pesticides when applied in water spray solutions. The disclosed agricultural spray adjuvants include glyphosate compositions comprising a strong mineral acid, such as sulfuric acid, and a polyamine surfactant, such as tallow amine or coco amine.

Abstract: A load bearing panel member having a first portion, a second portion, and an appearance surface portion is formed by injection molding such that the first portion includes a plurality of ribs forming a grid pattern on the first portion and another plurality of ribs extending toward the periphery of the first portion which may be non-orthogonal to each other and to the ribs forming the grid pattern. An appearance surface portion attached to the first portion and second portion of the panel member forms an integral hinge between the first and second portions of the panel member. The panel member may be configured as a floor panel of a vehicle.

Abstract: The embodiments described and claimed herein are rapid-release anchors and fittings for securing equipment to a surface of a vehicle. The embodiments described and claimed herein utilize a surface-mountable anchor capable of releasably engaging with a fitting. The anchor has channel with an open top end and an open bottom end that allow the anchor to be received and removed in both directions, up and down. The anchor includes a locking mechanism that is configured to permit single-handed insertion of the fitting into the anchor. Also disclosed herein are systems comprising multiple anchors and fittings that serve as brackets for the securement of larger devices, cabinets, handles and other pieces of equipment within a vehicle.