Abstract: Methods of synthesizing intermediates useful for the synthesis of halichondrin B analogs are described.

Abstract: The invention relates to an end piece (11) of a windshield wiper comprising at least one wiper blade (1). Said end piece (11) has a first part (12) and a second part (13) which are connected to each other by a removable attachment means, and a blocking means (28) for preventing the wiper blade (1) from moving relative to the end piece (11), said blocking means (28) comprising a securing device (33) and an actuating element (51). The securing device (33) is designed to pinch the wiper blade (1) and is subject to a force exerted by the actuating element (51). The end piece is for use in motor vehicles.

Abstract: Method of supplying an optical lens adapted to a wearer, includes: a) receiving, directly or indirectly via a manufacturing side, from a first networked computer entity located at a lens ordering side, a first set of data including at least wearer's prescription data, b) sending a second set of data including at least an optical lens design information and the wearer's prescription data to a second networked computer entity located at a lens designing side, and receiving from the second networked computer entity a third set of data including at least optical lens data calculated from the second set, and c) sending at least to a third networked computer entity, at a lens manufacturing side, a fourth set of data including at least part of the optical lens data, the at least optical lens data of the fourth set of data being at least partially modified by a masking function.

Abstract: A method for determining at least one optical conception parameter for a progressive ophthalmic lens intended to equip a frame of a wearer, depending on the visual behavior of the latter. The method comprises the following steps: a) collecting a plurality of behavioral measurements relating to a plurality of gaze directions and/or positions of the wearer during a visual task; b) statistically processing said plurality of behavioral measurements in order to determine a zone of use of the area of an eyeglass fitted in said frame, said zone of use being representative of a statistical spatial distribution of said plurality of behavioral measurements; and c) determining at least one optical conception parameter for said progressive ophthalmic lens depending on a spatial extent and/or position of the zone of use.

Abstract: The present invention pertains to a method for producing a colloidal suspension of zirconia particles, comprising the following successive steps: a) subjecting a mixture of zirconium oxychloride and an alkali metal halide in an aqueous solvent to hydrothermal treatment at a temperature above 150° C., so as to obtain a suspension in the form of a two-phase mixture comprising a slurry and a supernatant, b) without first peptizing it, desalting said suspension so as to form a colloidal suspension of zirconia.

Abstract: A method of preparing an aluminum alloy resin composite comprises: providing an aluminum alloy substrate having an oxide layer on a surface thereof, wherein the oxide layer has one or more nanopores; forming one or more corrosion pores on an outer surface of the oxide layer by using a corrosion agent, wherein the corrosion agent is at least one selected from a group of ammonia, ammonium salt, hydrazine, hydrazine derivative, and water-soluble amine compound; and injection molding a resin composition to the surface of the aluminum alloy substrate.

Abstract: A method and a system for controlling vehicle electric power, and a vehicle comprising the same, are provided. The method includes converting a first voltage supplied by at least one of a startup generator and a storage battery of the vehicle into a second voltage, and controlling the at least one of the startup generator and the storage battery to supply power to a first device with the first voltage, and to supply power to a second device with the second voltage. The system includes a startup generator and a storage battery, configured to supply a first voltage, and a converter configured to convert the first voltage into a second voltage. At least one of the startup generator and the storage battery is configured to supply power to a first device with the first voltage, and to supply power to a second device with the second voltage.

Abstract: A system includes a positioning and centering pin (4) configured to be attached to an ophthalmic lens, an attachment member (5) configured to be positioned on and attached to the pin and to be attached to the lens, a tool (20) for positioning the attachment member on the pin, and which includes a body (42) provided with at least one receiving recess configured to at least partially receive at least one of the attachment members and the pin, at least one centering member (48, 56) and at least one guide member (48, 57), which are configured such that, when the attachment member and the pin are mounted on the tool, the attachment member is centered relative to the body and the pin is guided relative to the body, whereby the attachment member is positioned in a predetermined position on the pin.

Abstract: A modular laboratory-style computer-controlled system for multistep chemical processing for use in laboratory automation or chemical production is disclosed. The system comprised a plurality of interconnectable electrically-powered controllable chemical process modules having chemical input and output ports and at least one communications interface. Interconnection among the chemical process modules include both chemical flow interconnections for the transport of chemical materials and network interconnections for the transport of communications signals. In some implementations chemical flow interconnections are software controllable.

Abstract: A window assembly includes a substrate with an electrically conductive transparent layer that defines an area having a periphery. An outer region devoid of the transparent layer is defined adjacent to and along the periphery. An elongated antenna element is disposed in the outer region. A feeding element couples to the antenna element for energizing the antenna element. The area of the transparent layer defines at least two protrusions being spaced apart from one another and extending integrally from the area and into the outer region. The antenna element abuts and is in direct electrical contact with the at least two protrusions. The feeding element couples to the antenna element at a location between the at least two protrusions or at one of the at least two protrusions.

Abstract: The invention relates to the technical field of measuring electric and magnetic properties, and specifically relates to a sample holder (1) to be connected to a device (2) for supporting a sample holder in order to measure the dielectric and/or magnetic properties of a sample (3), said supporting device (2) comprising: first and second connectors (4, 5) suitable for allowing an electromagnetic wave to pass therethrough, and for being connected to a means (6) for transmitting the electromagnetic wave and to a means (7) for circulating the electromagnetic wave after passing through the supporting device (2) and the sample holder (1), respectively, which is suitable for transmitting all or part of the electromagnetic wave from the first connector (4) to the second connector (5) according to a reference axis (x) and for being removably arranged therebetween, the sample holder (1) comprising an outer tubular body (11) that is coaxial to said reference axis (x), and a cavity (8) in which the sample (3) is to be hou

Abstract: According to detection results of a plurality of original document detectors, an image reading apparatus determines whether or not correcting skew of an original document is possible, controls a pair of a plurality of transport rollers in a case where it is determined that correcting the skew of the original document is possible, and corrects the skew of the original document by making transporting speeds of the pair of the plurality of transport rollers different from each other.

Abstract: A mirrored storage cabinet is disclosed, including: a cabinet body formed by a bottom plate and an upper frame, a lower frame, a left frame and a right frame installed at four sides of the bottom plate; and a cabinet door installed at an opening of the cabinet body, wherein a first separating plate and a second separating plate are provided on the bottom plate close to the left frame and the right frame, side mirrors are provided respectively above the left frame and the first separating plate and above the right frame and the second separating plate, LED light strips are installed below the side mirrors via supports on the bottom plate, a division plate is provided between the first separating plate and the second separating plate, and the cabinet door is movably installed at the side edge of the first separating plate.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat inflammatory bowel diseases, and processes and intermediates useful for preparing such compounds.

Abstract: The positioning signals broadcast by GNSS constellations are affected by significant errors, notably due to the crossing of the ionospheric layer or of the tropospheric layer. Several unwieldy means have been deployed to provide professional users with corrections of said errors. These means, however, all require the knowledge of at least one precise reference point at a given distance. According to the invention, positioning receivers that are not very precise, such as smartphones, present in a geographical zone, of unknown precise position, can contribute to the production of precise atmospheric error corrections if said receivers are sufficiently numerous.

Abstract: A facility management assistance device includes an image extractor that extracts an image of a target area from an image of the interior of the facility, an image presenter that presents the image of the target area to a first user, an individual evaluation information acquirer that acquires individual evaluation information on an evaluation result of the target area, in response to an input by the first user, an evaluation aggregation information generator that aggregates the individual evaluation information in a designated period, and generates evaluation aggregation information for listing an evaluation result for the designated period, an evaluation aggregation information presenter that presents the evaluation aggregation information to a second user, an improvement implementation information acquirer that acquires improvement implementation information on the implementation situation of an improvement measure, in response to an input by a second user, and an improvement implementation information pres

Abstract: The invention relates to a connector (6) for assembling a motor vehicle actuating arm with a wiper blade (2), said connector comprising; a transverse pin (8) intended to be linked to an actuating arm, said transverse pin (8) being located transversely between a first and a second lateral wall (10a, 10b) of the connector (6), a lateral connection interface (11) supported by one of the two lateral walls (10a, 10b), characterized in that the connector (6) moreover comprises at least one latching tab (19a, 19b) projecting from the lateral wall (10b) supporting the lateral connection interface (11), said latching tab (19a, 19b) being configured to cooperate with a lateral edge (20) of the connection platform (7). The present invention also relates to a connection device (3) and a wiper device (1).

Abstract: The invention provides a hair shaping composition suitable for topical application to hair, the composition comprising from 1 to 25 wt % of one or more C2-4 monoaldehydes and from 1 to 25 wt % of one or more urea compounds; dissolved or dispersed in an aqueous carrier.

Abstract: Provided is a self-cleaning method for a filter assembly of a washing machine, the method comprising: receiving a user operation instruction for starting a self-cleaning process; executing the self-cleaning process, so as to clean the filter assembly of the washing machine, and before the self-cleaning process is completed, only receiving user operation instructions for turning off the washing machine, pausing the self-cleaning process and unpausing the self-cleaning process, and prohibiting receipt of or ignoring the user operation instructions other than user operation instructions for turning off the washing machine, pausing the self-cleaning process and unpausing the self-cleaning process. According to the present invention, the filter assembly of the washing machine is thoroughly cleaned, prolonging the service life of the filter assembly in the washing machine and ensuring that the filter assembly always has a high filtration flux.