Abstract: Aminopeptidase inhibitory activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.1 and R.sub.2 are each independently hydrogen, alkyl, carboxyalkyl, halo-substituted alkyl, hydroxyalkyl, aminoalkyl, mercaptoalkyl, alkylthioalkyl, (cycloalkyl)alkyl, (heteroaryl)alkyl, arylalkyl, carbamoylalkyl, guanidinylalkyl or heteroaryl;R.sub.3 is hydrogen, alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl, (heteroaryl)alkyl, ##STR2## R.sub.4 and R.sub.5 are each independently hydrogen, alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl, or (heteroaryl)alkyl;A is glycyl, alanyl, leucyl, phenylalanyl, arginyl, sarcosyl, seryl, asparagyl, lysyl, glutamyl, histidyl, tryptophyl, cysteinyl, methionyl, threonyl, tyrosyl, valyl, aspartyl, prolyl, norleucyl, or norvalyl; andn is an integer of 1 to 6.

Abstract: A hydroxy functional epoxy-polyester graft copolymer and solvent-based thermosetting coating composition comprising said copolymer and polyfunctional, hydroxy-reactive crosslinking agent. The coating composition may be formulated as hot sprayable, high solids coating composition suitable for use as chip resistant automotive vehicle primer suitable for use on body panel areas subject to chipping by stones, gravel and other road debris. The composition also may be formulated as a high solids composition sprayable with conventional spraying equipment. The hydroxy functional epoxy-polyester graft copolymer is the product of polymerization of lactone monomers in presence of hydroxy functional epoxy ester resin precursor. The precursor resin is the product of modified diepoxide and hydroxy functional secondary amine, the modified diepoxide being the product of the polymerization of lactone monomers in the presence of diepoxide which has been chain extended with dicarboxylic acid.

Abstract: Hydrocyanation of butadiene using a mixed ligand zerovalent nickel catalyst wherein the mixture of phosphite ligands there is 10 to 65 mol percent phenyl, and a complemental amount of meta- and para-tolyl.

Abstract: Analogs of arachidonic acid are provided having the structure ##STR1## wherein R is CH.sub.2 OH or CO.sub.2 H and m is 1 or 2. These compounds are useful as inhibitors of leukotriene and prostaglandin biosynthesis and as such are useful an antiallergy and antiinflammatory agents.

Abstract: An industrial exhaust ventilation system enabling access to exhaust generating processes while containing and controlling the resultant exhausted gases is provided. A cover assembly is attached to the structure generating the exhaust gases and is provided with a reciprocating cover having an open and closed position. The exhaust generating process is accessible only when the cover is open. A conventional exhaust system is also provided to maintain the low level of air circulation necessary to convey the generated exhaust to a treatment facility. The ventilation system is optionally provided with a workload enclosure that travels to selected process structures and forms a fume containment region by interengaging with the cover assembly located thereon.

Abstract: Technetium-99m labeled dioxime complexes are useful for imaging the myocardium, brain and hepatobiliary system, in humans and other mammalian species.

Abstract: This invention relates to a process for preparing melt-processible tetrafluoroethylene perfluoro(alkyl vinyl ether) (TFE/PAVE) copolymer granules having good particle flow characteristics and thermal stability, and to the product of the process.

Abstract: A dispensing apparatus for dispensing two strip materials, each carried on a separate spool, includes a hub having a slot therein which exposes a portion of one but not the other of the spools. A friction producing member is extensible through the slot and into friction generating engagement with the selected one of the spools to exert a drag force on one of the spools to the exclusion of the other. The friction producing member is received in a groove formed in a spindle so that torque imposed on the member by rotation of the spool is transmitted to the spindle.

Abstract: An advancing, reinforced, thermoplastic tape is pressed on a partially built, composite structure as the mating surfaces are heated to the melting point by a beam of high temperature, radiant energy. The center of the beam is directed at the structure, in advance of the nip between the tape and structure.

Abstract: A deep trench is excavated into a sea bottom. The trench is filled with a slurry, e.g. clay and water, to maintain trench integrity for a period of time. A pipeline is subsequently lowered to the trench bottom by either gravity settlement, jet down using water jets, or vibration.

Abstract: In emulsion blend explosives, the replacement of coarse salt particles, e.g., prills, by fines, i.e., particles which pass a No. 50 U.S. sieve, increases the water resistance of the explosive without deleteriously affecting its shelf life provided that the explosive, prior to such replacement, is storage-stable as determined by the Salt Extraction and lead compression tests described herein. Products containing a combination of whole and crushed ammonium nitrate prills, and emulsions made with an anionic emulsifying agent such as a fatty acid salt, are preferred. Depending on the fines content and chemical composition, other properties such as sensitivity to initiation and detonation velocity also may be improved.

Abstract: A wide area paging system is disclosed in which paging messages input to the system in one local area can be broadcast to a receiver in any other local area without necessarily broadcasting the message in all areas. A local area clearinghouse in each area stores resident subscriber data including current location and receiver serial number. This data is used to transfer messages over a data network to the correct clearinghouse. The system uses a TDM data protocol. The data is encoded and transmitted at a very high rate (e.g., 19,000 baud) in short packets (256 bits/13 milliseconds) via stereo FM sidebands. Receivers are assigned to receive sequentially numbered time slots matching a portion of their address. The addresses of intended receivers are included in the data packets. Battery-powered receivers are deactivated between packets and reactivated in accordance with the sequential time slot number scheme to receive an incoming packet.

Abstract: A connector unit is provided which includes a housing having connection terminals in its opening, and a movable member adapted to be inserted into the opening of the housing. The movable member has cam projections each extending from one end, where the movable member is inserted into the housing, toward the other end, over a proper length. When the movable member is partially inserted into the opening of the housing, an elastic contact portion of the connection terminal is pressed by the cam projection to provide such a clearance as to allow the conductor to be inserted there.

Abstract: Glycoside-containing polyester products having improved color characteristics are provided by a polyester preparation process in which a polyol reactant containing at least a minor proportion of a glycoside reactant is reacted with a lower alkyl ester of a polybasic acid. The color characteristics of such products are notably improved relative to that which is obtained when said reaction is instead conducted using the corresponding polybasic acid or anhydride in place of the indicated lower alkyl ester thereof.The color improvement benefits of the present invention are particularly pronounced and dramatic when the polybasic acid component of the desired polyester product comprises an aromatic polybasic acid and when a lower alkyl ester of said aromatic polybasic acid is employed in the reaction in place of the aromatic acid itself.

Abstract: Water-dispersible synthetic fiber of cruciform cross-section to promote dispersibility, and so better uniformity, more opacity, good permeability and an attractive flannel-like hand to the resulting wet-laid fabrics.

Abstract: A process for curing a coating composition with a vaporous amine catalyst, wherein the composition has as the binder A. an acrylic polymer containing hydroxyl groups and amine containing groups and has a weight average molecular weight of about 2,000-50,000 andB. an aliphatic polyisocyanate.

Abstract: An apparatus for radially quenching melt spun filaments features a quenching chamber having a foraminous distribution cylinder between the filaments and the gas supply chamber with areas of decreasing porosity from a location immediately below the spinneret toward the exit of the quench chamber.

Abstract: A thermosetting coating composition with excellent weatherability adapted for use as an automotive topcoat which upon curing forms a hard, glossy, durable coating. The coating composition, which reacts in situ during curing, is characterized by comprising a mixture of:(A) polyol having a number average molecular weight (MHD n) of between about 130-5000;(B) dicarboxylic acid anhydride comprising at least about 50 weight percent of alkyl hexahydrophthalic anhydride;(C) epoxy having one or more epoxide groups per molecule and a number average molecular weight (M.sub.n) of between about 130-1500; and(D) an amine-aldehyde crosslinking agent.

Abstract: A composition and method for preparing it is disclosed. The composition in a blend of a cured fluoroelastomer which except for the cure sites is a perfluorocarbon and a thermoplastic copolymer of tetrafluoroethylene which is present as generally spherical particles having a particle size of less than 10 microns. The composition is prepared by blending the fluoroelastomer and thermoplastic copolymer at a temperature above the melting point of the thermoplastic copolymer followed by curing the fluoroelastomer.

Abstract: A co-spray method for preparing homogeneous hybrid powders suitable for preparing tablets is provided. The tablets are useful as reagent carriers for diagnostic assays.